CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: vanadium atom
Accession: CHEBI:27698
browse the term
Definition: A vanadium group element atom that has formula V.
Synonyms: related_synonym: 23V; Formula=V; InChI=1S/V; InChIKey=LEONUFNNVUYDNQ-UHFFFAOYSA-N; SMILES=[V]; V; vanadio; vanadium
alt_id: CHEBI:27274; CHEBI:9930
xref: CAS:7440-62-2; KEGG:C06267
xref_mesh: MESH:D014639
xref: WebElements:V
G
Abl1
ABL proto-oncogene 1, non-receptor tyrosine kinase
increases expression
ISO
Vanadium results in increased expression of ABL1 mRNA
CTD
PMID:19000753
NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
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Aco1
aconitase 1
increases activity
ISO
Vanadium results in increased activity of ACO1 protein
CTD
PMID:16386771
NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
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Adam17
ADAM metallopeptidase domain 17
increases expression
ISO
Vanadium results in increased expression of ADAM17 mRNA
CTD
PMID:19000753
NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
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Adamts4
ADAM metallopeptidase with thrombospondin type 1 motif, 4
decreases expression
ISO
Vanadium results in decreased expression of ADAMTS4 mRNA
CTD
PMID:19000753
NCBI chr13:83,670,556...83,680,045
Ensembl chr13:83,670,183...83,680,065
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Adipoq
adiponectin, C1Q and collagen domain containing
multiple interactions
ISO
NL-71-101 inhibits the reaction [Vanadium results in increased expression of ADIPOQ protein]; Vanadium results in increased expression of and results in increased secretion of ADIPOQ protein
CTD
PMID:16524741
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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Ahr
aryl hydrocarbon receptor
multiple interactions
ISO
Vanadium inhibits the reaction [[AHR protein binds to ARNT protein] which binds to CYP1A1 promoter] Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]
CTD
PMID:18541696 PMID:23423713
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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Akt1
AKT serine/threonine kinase 1
multiple interactions
ISO
PRKCA protein affects the reaction [Vanadium results in increased phosphorylation of and results in increased activity of AKT1 protein]; PRKCI protein mutant form inhibits the reaction [Vanadium results in increased phosphorylation of and results in increased activity of AKT1 protein]; Vanadium results in increased phosphorylation of and results in increased activity of AKT1 protein
CTD
PMID:14971662
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Alk
ALK receptor tyrosine kinase
decreases expression
ISO
Vanadium results in decreased expression of ALK mRNA
CTD
PMID:19000753
NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034
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Aoc3
amine oxidase, copper containing 3
decreases expression
ISO
Vanadium results in decreased expression of AOC3 mRNA
CTD
PMID:19000753
NCBI chr10:86,272,757...86,280,702
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Arnt
aryl hydrocarbon receptor nuclear translocator
multiple interactions
ISO
Vanadium inhibits the reaction [[AHR protein binds to ARNT protein] which binds to CYP1A1 promoter]
CTD
PMID:18541696
NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
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Atp1b4
ATPase Na+/K+ transporting family member beta 4
decreases expression
ISO
Vanadium results in decreased expression of ATP1B4 mRNA
CTD
PMID:19000753
NCBI chr X:117,087,284...117,108,023
Ensembl chr X:117,057,423...117,108,020
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Atp2a3
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
increases expression
ISO
Vanadium results in increased expression of ATP2A3 mRNA
CTD
PMID:19000753
NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748
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Atp2b1
ATPase plasma membrane Ca2+ transporting 1
increases expression
ISO
Vanadium results in increased expression of ATP2B1 mRNA
CTD
PMID:19000753
NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295
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Atp2b2
ATPase plasma membrane Ca2+ transporting 2
increases expression
ISO
Vanadium results in increased expression of ATP2B2 mRNA
CTD
PMID:19000753
NCBI chr 4:146,894,602...147,208,060
Ensembl chr 4:146,896,332...147,140,665
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Atp5f1b
ATP synthase F1 subunit beta
increases expression
ISO
Vanadium results in increased expression of ATP5F1B mRNA
CTD
PMID:19000753
NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
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Atp5mf
ATP synthase membrane subunit f
increases expression
ISO
Vanadium results in increased expression of ATP5MF mRNA
CTD
PMID:19000753
NCBI chr12:9,421,665...9,428,236
Ensembl chr12:9,421,579...9,428,236
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Atp5mg
ATP synthase membrane subunit G
increases expression
ISO
Vanadium results in increased expression of ATP5MG mRNA
CTD
PMID:19000753
NCBI chr 8:45,225,680...45,233,630
Ensembl chr 8:45,225,686...45,233,559
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Atp5po
ATP synthase peripheral stalk subunit OSCP
increases expression
ISO
Vanadium results in increased expression of ATP5PO mRNA
CTD
PMID:19000753
NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592
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Atp6ap1
ATPase H+ transporting accessory protein 1
decreases expression
ISO
Vanadium results in decreased expression of ATP6AP1 mRNA
CTD
PMID:19000753
NCBI chr X:152,079,954...152,087,034
Ensembl chr X:152,079,865...152,087,034
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Atp6ap2
ATPase H+ transporting accessory protein 2
increases expression
ISO
Vanadium results in increased expression of ATP6AP2 mRNA
CTD
PMID:19000753
NCBI chr X:10,183,983...10,210,948
Ensembl chr X:10,183,068...10,210,918
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Atp6v0b
ATPase H+ transporting V0 subunit B
decreases expression
ISO
Vanadium results in decreased expression of ATP6V0B mRNA
CTD
PMID:19000753
NCBI chr 5:131,423,384...131,424,900
Ensembl chr 5:131,423,387...131,426,401
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Atp6v0c
ATPase H+ transporting V0 subunit C
decreases expression
ISO
Vanadium results in decreased expression of ATP6V0C mRNA
CTD
PMID:19000753
NCBI chr10:13,196,204...13,202,580
Ensembl chr10:13,196,204...13,201,500
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Atp6v1a
ATPase H+ transporting V1 subunit A
increases expression
ISO
Vanadium results in increased expression of ATP6V1A mRNA
CTD
PMID:19000753
NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
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Bmx
BMX non-receptor tyrosine kinase
decreases expression
ISO
Vanadium results in decreased expression of BMX mRNA
CTD
PMID:19000753
NCBI chr X:30,227,251...30,290,015
Ensembl chr X:30,227,251...30,289,993
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Braf
B-Raf proto-oncogene, serine/threonine kinase
decreases expression
ISO
Vanadium results in decreased expression of BRAF mRNA
CTD
PMID:19000753
NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
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Cacna1f
calcium voltage-gated channel subunit alpha1 F
increases expression
ISO
Vanadium results in increased expression of CACNA1F mRNA
CTD
PMID:19000753
NCBI chr X:14,868,096...14,896,413
Ensembl chr X:14,868,024...14,896,413
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Cacna2d2
calcium voltage-gated channel auxiliary subunit alpha2delta 2
increases expression
ISO
Vanadium results in increased expression of CACNA2D2 mRNA
CTD
PMID:19000753
NCBI chr 8:108,072,208...108,203,516
Ensembl chr 8:108,072,454...108,203,173
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Cacnb1
calcium voltage-gated channel auxiliary subunit beta 1
decreases expression
ISO
Vanadium results in decreased expression of CACNB1 mRNA
CTD
PMID:19000753
NCBI chr10:82,998,182...83,018,838
Ensembl chr10:82,998,182...83,018,694
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Cacng4
calcium voltage-gated channel auxiliary subunit gamma 4
decreases expression
ISO
Vanadium results in decreased expression of CACNG4 mRNA
CTD
PMID:19000753
NCBI chr10:92,683,778...92,745,842
Ensembl chr10:92,683,761...92,746,126
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Camkk2
calcium/calmodulin-dependent protein kinase kinase 2
decreases expression
ISO
Vanadium results in decreased expression of CAMKK2 mRNA
CTD
PMID:19000753
NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279
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Cat
catalase
decreases activity multiple interactions
EXP
Vanadium results in decreased activity of CAT protein Testosterone Propionate inhibits the reaction [Vanadium results in decreased activity of CAT protein]
CTD
PMID:20521886
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Ccn1
cellular communication network factor 1
decreases expression
ISO
Vanadium results in decreased expression of CCN1 mRNA
CTD
PMID:19000753
NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
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Cd36
CD36 molecule
decreases expression
ISO
Vanadium results in decreased expression of CD36 mRNA
CTD
PMID:19000753
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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Cdk16
cyclin-dependent kinase 16
decreases expression
ISO
Vanadium results in decreased expression of CDK16 mRNA
CTD
PMID:19000753
NCBI chr X:1,492,814...1,504,309
Ensembl chr X:1,492,814...1,504,148
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Cdk17
cyclin-dependent kinase 17
decreases expression
ISO
Vanadium results in decreased expression of CDK17 mRNA
CTD
PMID:19000753
NCBI chr 7:27,683,890...27,765,814
Ensembl chr 7:27,683,890...27,764,910
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Cdk6
cyclin-dependent kinase 6
increases expression
ISO
Vanadium results in increased expression of CDK6 mRNA
CTD
PMID:19000753
NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
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Cdk8
cyclin-dependent kinase 8
decreases expression
ISO
Vanadium results in decreased expression of CDK8 mRNA
CTD
PMID:19000753
NCBI chr12:8,737,198...8,805,026
Ensembl chr12:8,737,262...8,804,177
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Chat
choline O-acetyltransferase
decreases expression multiple interactions
EXP
Vanadium results in decreased expression of CHAT protein Nicotine inhibits the reaction [Vanadium results in decreased expression of CHAT protein]
CTD
PMID:22119111
NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
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Clu
clusterin
increases expression
ISO
Vanadium results in increased expression of CLU mRNA
CTD
PMID:19000753
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
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Col1a1
collagen type I alpha 1 chain
decreases expression
ISO
Vanadium results in decreased expression of COL1A1 mRNA
CTD
PMID:19000753
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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Col4a6
collagen type IV alpha 6 chain
decreases expression
ISO
Vanadium results in decreased expression of COL4A6 mRNA
CTD
PMID:19000753
NCBI chr X:104,766,463...105,117,499
Ensembl chr X:104,766,957...105,117,500
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Col5a1
collagen type V alpha 1 chain
decreases expression
ISO
Vanadium results in decreased expression of COL5A1 mRNA
CTD
PMID:19000753
NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588
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Csk
C-terminal Src kinase
decreases expression
ISO
Vanadium results in decreased expression of CSK mRNA
CTD
PMID:19000753
NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292
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Csnk1a1
casein kinase 1, alpha 1
decreases expression
ISO
Vanadium results in decreased expression of CSNK1A1 mRNA
CTD
PMID:19000753
NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271
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Csnk2a2
casein kinase 2 alpha 2
decreases expression
ISO
Vanadium results in decreased expression of CSNK2A2 mRNA
CTD
PMID:19000753
NCBI chr19:9,556,443...9,596,080
Ensembl chr19:9,556,260...9,596,080
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Cux1
cut-like homeobox 1
increases activity
ISO
Vanadium results in increased activity of CUX1 protein
CTD
PMID:19000753
NCBI chr12:20,107,062...20,425,868
Ensembl chr12:20,107,311...20,425,866
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Cxcl2
C-X-C motif chemokine ligand 2
increases expression
EXP
Vanadium results in increased expression of CXCL2 mRNA
CTD
PMID:11708899
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
multiple interactions decreases expression
ISO
Vanadium inhibits the reaction [[AHR protein binds to ARNT protein] which binds to CYP1A1 promoter]; Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A1 protein]; Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A1 protein]; Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Vanadium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A1 protein]; Vanadium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] Vanadium results in decreased expression of CYP1A1 mRNA
CTD
PMID:18541696 PMID:20221682 PMID:23423713
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
multiple interactions
ISO
Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein]; Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Vanadium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein]; Vanadium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]
CTD
PMID:23423713
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
multiple interactions
ISO
Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1B1 protein]; Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]; Vanadium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1B1 protein]; Vanadium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
CTD
PMID:23423713
NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
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Dgkb
diacylglycerol kinase, beta
increases expression
ISO
Vanadium results in increased expression of DGKB mRNA
CTD
PMID:19000753
NCBI chr 6:54,640,948...55,397,210
Ensembl chr 6:54,641,614...55,397,043
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Dgkg
diacylglycerol kinase, gamma
decreases expression
ISO
Vanadium results in decreased expression of DGKG mRNA
CTD
PMID:19000753
NCBI chr11:78,384,212...78,579,158
Ensembl chr11:78,384,458...78,577,212
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Dgki
diacylglycerol kinase, iota
increases expression
ISO
Vanadium results in increased expression of DGKI mRNA
CTD
PMID:19000753
NCBI chr 4:65,410,878...65,872,733
Ensembl chr 4:65,420,108...65,872,733
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Dgkq
diacylglycerol kinase, theta
decreases expression
ISO
Vanadium results in decreased expression of DGKQ mRNA
CTD
PMID:19000753
NCBI chr14:1,059,125...1,073,131
Ensembl chr14:1,059,170...1,073,131
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Etv4
ETS variant transcription factor 4
increases activity
ISO
Vanadium results in increased activity of ETV4 protein
CTD
PMID:19000753
NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974
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Fgf17
fibroblast growth factor 17
decreases expression
ISO
Vanadium results in decreased expression of FGF17 mRNA
CTD
PMID:19000753
NCBI chr15:45,711,498...45,717,622
Ensembl chr15:45,711,998...45,717,063
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Fgfbp1
fibroblast growth factor binding protein 1
decreases expression
ISO
Vanadium results in decreased expression of FGFBP1 mRNA
CTD
PMID:19000753
NCBI chr14:67,103,686...67,107,492
Ensembl chr14:67,104,545...67,107,496
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Fshb
follicle stimulating hormone subunit beta
decreases expression
EXP
Vanadium results in decreased expression of FSHB protein
CTD
PMID:20521886
NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
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Gja1
gap junction protein, alpha 1
increases expression
EXP
Vanadium results in increased expression of GJA1 mRNA
CTD
PMID:15159208
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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Gp1bb
glycoprotein Ib platelet subunit beta
decreases expression
ISO
Vanadium results in decreased expression of GP1BB mRNA
CTD
PMID:19000753
NCBI chr11:82,378,216...82,379,393
Ensembl chr11:82,378,199...82,379,392
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Hgf
hepatocyte growth factor
decreases expression
ISO
Vanadium results in decreased expression of HGF mRNA
CTD
PMID:19000753
NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
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Hif1a
hypoxia inducible factor 1 subunit alpha
multiple interactions
ISO
Vanadium results in increased expression of and results in increased activity of HIF1A protein
CTD
PMID:16386771
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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Hspa1a
heat shock protein family A (Hsp70) member 1A
increases expression
EXP
Vanadium results in increased expression of HSPA1A mRNA
CTD
PMID:15159208
NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
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Icam1
intercellular adhesion molecule 1
multiple interactions
ISO
[Particulate Matter results in increased abundance of Vanadium] which results in increased expression of ICAM1 protein
CTD
PMID:26732377
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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Icam4
intercellular adhesion molecule 4, Landsteiner-Wiener blood group
decreases expression
ISO
Vanadium results in decreased expression of ICAM4 mRNA
CTD
PMID:19000753
NCBI chr 8:19,566,075...19,567,171
Ensembl chr 8:19,566,075...19,567,171
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Ifng
interferon gamma
multiple interactions
ISO
[Air Pollutants results in increased abundance of Vanadium] which results in decreased methylation of IFNG promoter
CTD
PMID:28424066
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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Igfbp4
insulin-like growth factor binding protein 4
decreases expression
ISO
Vanadium results in decreased expression of IGFBP4 mRNA
CTD
PMID:19000753
NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
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Igfbp5
insulin-like growth factor binding protein 5
increases expression
ISO
Vanadium results in increased expression of IGFBP5 mRNA
CTD
PMID:19000753
NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
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Il10
interleukin 10
multiple interactions
EXP
[Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] inhibits the reaction [Streptozocin results in decreased expression of IL10 protein]
CTD
PMID:15862027
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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Il1a
interleukin 1 alpha
increases expression
EXP
Vanadium results in increased expression of IL1A mRNA
CTD
PMID:15159208
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
G
Il4
interleukin 4
multiple interactions
EXP ISO
[Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] results in increased expression of IL4 protein [Air Pollutants results in increased abundance of Vanadium] which results in decreased methylation of IL4 promoter
CTD
PMID:15862027 PMID:28424066
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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Il6
interleukin 6
increases expression
ISO EXP
Vanadium results in increased expression of IL6 mRNA; Vanadium results in increased expression of IL6 protein
CTD
PMID:9344885 PMID:15159208
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Ins1
insulin 1
multiple interactions
ISO
[Selenium co-treated with Vitamin E co-treated with Vanadium co-treated with Chromium] results in increased expression of INS1 mRNA; [Selenium co-treated with Vitamin E co-treated with Vanadium co-treated with Chromium] results in increased expression of INS1 protein
CTD
PMID:20108212
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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Insig1
insulin induced gene 1
decreases expression
ISO
Vanadium results in decreased expression of INSIG1 mRNA
CTD
PMID:19000753
NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
G
Insl5
insulin like 5
increases expression
ISO
Vanadium results in increased expression of INSL5 mRNA
CTD
PMID:19000753
NCBI chr 5:117,773,104...117,777,376
G
Irf1
interferon regulatory factor 1
increases activity
ISO
Vanadium results in increased activity of IRF1 protein
CTD
PMID:19000753
NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
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Itga10
integrin subunit alpha 10
decreases expression
ISO
Vanadium results in decreased expression of ITGA10 mRNA
CTD
PMID:19000753
NCBI chr 2:184,182,869...184,202,172
Ensembl chr 2:184,182,869...184,202,172
G
Itga3
integrin subunit alpha 3
decreases expression
ISO
Vanadium results in decreased expression of ITGA3 mRNA
CTD
PMID:19000753
NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118
G
Itgax
integrin subunit alpha X
decreases expression
ISO
Vanadium results in decreased expression of ITGAX mRNA
CTD
PMID:19000753
NCBI chr 1:182,709,653...182,740,709
Ensembl chr 1:182,719,609...182,740,698
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Itgb7
integrin subunit beta 7
increases expression
ISO
Vanadium results in increased expression of ITGB7 mRNA
CTD
PMID:19000753
NCBI chr 7:133,347,927...133,364,955
Ensembl chr 7:133,347,960...133,364,876
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Jak3
Janus kinase 3
decreases expression
ISO
Vanadium results in decreased expression of JAK3 mRNA
CTD
PMID:19000753
NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536
G
Kcna3
potassium voltage-gated channel subfamily A member 3
decreases expression
ISO
Vanadium results in decreased expression of KCNA3 mRNA
CTD
PMID:19000753
NCBI chr 2:194,632,106...194,634,059
Ensembl chr 2:194,632,196...194,650,138
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Kcnc1
potassium voltage-gated channel subfamily C member 1
decreases expression
ISO
Vanadium results in decreased expression of KCNC1 mRNA
CTD
PMID:19000753
NCBI chr 1:96,902,953...96,944,744
Ensembl chr 1:96,902,953...96,944,744
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Kcnq1
potassium voltage-gated channel subfamily Q member 1
increases expression
EXP
Vanadium results in increased expression of KCNQ1 mRNA
CTD
PMID:15159208
NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
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Kcnq3
potassium voltage-gated channel subfamily Q member 3
increases expression
ISO
Vanadium results in increased expression of KCNQ3 mRNA
CTD
PMID:19000753
NCBI chr 7:97,730,219...98,025,652
Ensembl chr 7:97,730,465...98,025,653
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Kcnq4
potassium voltage-gated channel subfamily Q member 4
decreases expression
ISO
Vanadium results in decreased expression of KCNQ4 mRNA
CTD
PMID:19000753
NCBI chr 5:134,275,145...134,326,992
Ensembl chr 5:134,275,934...134,326,932
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Klf11
KLF transcription factor 11
decreases expression
ISO
Vanadium results in decreased expression of KLF11 mRNA
CTD
PMID:19000753
NCBI chr 6:41,285,699...41,297,548
Ensembl chr 6:41,285,842...41,297,550
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Lep
leptin
multiple interactions
EXP
Vanadium promotes the reaction [LEP protein results in increased expression of UCP1 protein]; Vanadium promotes the reaction [LEP protein results in increased phosphorylation of STAT3 protein]
CTD
PMID:16195403
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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Lhb
luteinizing hormone subunit beta
decreases expression multiple interactions
EXP
Vanadium results in decreased expression of LHB protein Vanadium inhibits the reaction [Vanadium results in decreased expression of LHB protein]
CTD
PMID:20521886
NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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Litaf
lipopolysaccharide-induced TNF factor
multiple interactions
ISO
[Titanium co-treated with Vanadium co-treated with Aluminum] results in increased expression of LITAF mRNA
CTD
PMID:17408380
NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763
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Map2k6
mitogen-activated protein kinase kinase 6
increases expression
ISO
Vanadium results in increased expression of MAP2K6 mRNA
CTD
PMID:19000753
NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
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Map3k14
mitogen-activated protein kinase kinase kinase 14
decreases expression
ISO
Vanadium results in decreased expression of MAP3K14 mRNA
CTD
PMID:19000753
NCBI chr10:88,165,349...88,215,558
Ensembl chr10:88,165,351...88,215,523
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Map3k2
mitogen activated protein kinase kinase kinase 2
increases expression
ISO
Vanadium results in increased expression of MAP3K2 mRNA
CTD
PMID:19000753
NCBI chr18:23,807,218...23,879,722
Ensembl chr18:23,807,218...23,871,433
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Map3k4
mitogen activated protein kinase kinase kinase 4
decreases expression
ISO
Vanadium results in decreased expression of MAP3K4 mRNA
CTD
PMID:19000753
NCBI chr 1:48,431,801...48,519,358
Ensembl chr 1:48,431,830...48,519,358
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Map4k4
mitogen-activated protein kinase kinase kinase kinase 4
decreases expression
ISO
Vanadium results in decreased expression of MAP4K4 mRNA
CTD
PMID:19000753
NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698
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Mapk1
mitogen activated protein kinase 1
multiple interactions increases phosphorylation
EXP ISO
[Vanadium co-treated with Iron] results in increased phosphorylation of MAPK1 protein; Vanadium results in increased phosphorylation of and results in increased activity of MAPK1 protein Vanadium results in increased phosphorylation of MAPK1 protein
CTD
PMID:14622970 PMID:16079071 PMID:16728372
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk3
mitogen activated protein kinase 3
multiple interactions increases phosphorylation
EXP ISO
[Vanadium co-treated with Iron] results in increased phosphorylation of MAPK3 protein; Vanadium results in increased phosphorylation of and results in increased activity of MAPK3 protein Vanadium results in increased phosphorylation of MAPK3 protein
CTD
PMID:14622970 PMID:16079071 PMID:16728372
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mapkapk3
MAPK activated protein kinase 3
increases expression
ISO
Vanadium results in increased expression of MAPKAPK3 mRNA
CTD
PMID:19000753
NCBI chr 8:107,929,754...107,963,638
Ensembl chr 8:107,929,762...107,963,568
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Megf8
multiple EGF-like-domains 8
increases expression
ISO
Vanadium results in increased expression of MEGF8 mRNA
CTD
PMID:19000753
NCBI chr 1:80,902,236...80,951,614
Ensembl chr 1:80,902,574...80,951,613
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Mfap2
microfibril associated protein 2
increases expression
ISO
Vanadium results in increased expression of MFAP2 mRNA
CTD
PMID:19000753
NCBI chr 5:153,312,068...153,320,266
Ensembl chr 5:153,314,711...153,320,259
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Mki67
marker of proliferation Ki-67
multiple interactions
EXP
Vanadium inhibits the reaction [2-Acetylaminofluorene results in increased expression of MKI67 protein]
CTD
PMID:15565650
NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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Mmp1
matrix metallopeptidase 1
decreases expression
ISO
Vanadium results in decreased expression of MMP1 mRNA
CTD
PMID:19000753
NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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Mmp14
matrix metallopeptidase 14
increases expression
ISO
Vanadium results in increased expression of MMP14 mRNA
CTD
PMID:19000753
NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
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Mst1r
macrophage stimulating 1 receptor
decreases expression
ISO
Vanadium results in decreased expression of MST1R mRNA
CTD
PMID:19000753
NCBI chr 8:108,596,100...108,611,441
Ensembl chr 8:108,597,299...108,612,455
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Mt1
metallothionein 1
multiple interactions
EXP
Vanadium inhibits the reaction [2-Acetylaminofluorene results in increased expression of MT1A protein]
CTD
PMID:15565650
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049
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Muc5ac
mucin 5AC, oligomeric mucus/gel-forming
increases expression
ISO
Vanadium results in increased expression of MUC5AC mRNA
CTD
PMID:10637131
NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475
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Myo18a
myosin XVIIIa
decreases expression
ISO
Vanadium results in decreased expression of MYO18A mRNA
CTD
PMID:19000753
NCBI chr10:62,654,218...62,755,465
Ensembl chr10:62,654,281...62,755,468
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Ndrg1
N-myc downstream regulated 1
increases expression
ISO
Vanadium results in increased expression of NDRG1 protein
CTD
PMID:16386771
NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
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Nedd9
neural precursor cell expressed, developmentally down-regulated 9
increases activity
ISO
Vanadium results in increased activity of NEDD9 protein
CTD
PMID:19000753
NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019
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Nos2
nitric oxide synthase 2
multiple interactions
EXP ISO
Vanadium inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of NOS2 mRNA] [Air Pollutants results in increased abundance of Vanadium] which results in decreased methylation of NOS2 promoter
CTD
PMID:18155637 PMID:28424066
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Nos3
nitric oxide synthase 3
increases expression
ISO
Vanadium results in increased expression of NOS3 mRNA
CTD
PMID:19000753
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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Npy
neuropeptide Y
increases expression
ISO
Vanadium results in increased expression of NPY mRNA
CTD
PMID:19000753
NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
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Nqo1
NAD(P)H quinone dehydrogenase 1
multiple interactions decreases expression increases stability
ISO
Vanadium inhibits the reaction [sulforaphane affects the localization of NQO1 protein]; Vanadium inhibits the reaction [sulforaphane results in increased activity of NQO1 protein]; Vanadium inhibits the reaction [sulforaphane results in increased expression of NQO1 mRNA]; Vanadium inhibits the reaction [sulforaphane results in increased expression of NQO1 protein]; Vanadium inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of NQO1 protein]; Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]; Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 protein] Vanadium results in decreased expression of NQO1 mRNA Vanadium results in increased stability of NQO1 protein
CTD
PMID:19367690
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Nrcam
neuronal cell adhesion molecule
decreases expression
ISO
Vanadium results in decreased expression of NRCAM mRNA
CTD
PMID:19000753
NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992
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P4hb
prolyl 4-hydroxylase subunit beta
decreases expression
ISO
Vanadium results in decreased expression of P4HB mRNA
CTD
PMID:19000753
NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
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Pcna
proliferating cell nuclear antigen
multiple interactions
EXP
Vanadium inhibits the reaction [2-Acetylaminofluorene results in increased expression of PCNA protein]; Vanadium inhibits the reaction [Diethylnitrosamine results in increased expression of PCNA protein]
CTD
PMID:16352317 PMID:16878318
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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Pecam1
platelet and endothelial cell adhesion molecule 1
decreases expression
ISO
Vanadium results in decreased expression of PECAM1 mRNA
CTD
PMID:19000753
NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
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Pfkp
phosphofructokinase, platelet
decreases expression
ISO
Vanadium results in decreased expression of PFKP mRNA
CTD
PMID:19000753
NCBI chr17:63,729,743...63,794,026
Ensembl chr17:63,729,780...63,794,018
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Pick1
protein interacting with PRKCA 1
decreases expression
ISO
Vanadium results in decreased expression of PICK1 mRNA
CTD
PMID:19000753
NCBI chr 7:110,796,623...110,816,850
Ensembl chr 7:110,797,117...110,816,848
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Pik3r3
phosphoinositide-3-kinase regulatory subunit 3
increases expression
ISO
Vanadium results in increased expression of PIK3R3 mRNA
CTD
PMID:19000753
NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583
G
Pkn1
protein kinase N1
decreases expression
ISO
Vanadium results in decreased expression of PKN1 mRNA
CTD
PMID:19000753
NCBI chr19:24,442,130...24,470,107
Ensembl chr19:24,442,122...24,470,107
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Pla2g2a
phospholipase A2 group IIA
increases expression
ISO
Vanadium results in increased expression of PLA2G2A mRNA
CTD
PMID:19000753
NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
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Plau
plasminogen activator, urokinase
increases expression
ISO
Vanadium results in increased expression of PLAU mRNA
CTD
PMID:19000753
NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
G
Prkaca
protein kinase cAMP-activated catalytic subunit alpha
decreases expression
ISO
Vanadium results in decreased expression of PRKACA mRNA
CTD
PMID:19000753
NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
G
Prkca
protein kinase C, alpha
multiple interactions
ISO
PRKCA protein affects the reaction [Vanadium results in increased phosphorylation of and results in increased activity of AKT1 protein]; PRKCA protein affects the reaction [Vanadium results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]
CTD
PMID:14971662
NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
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Prkcb
protein kinase C, beta
decreases expression
ISO
Vanadium results in decreased expression of PRKCB mRNA
CTD
PMID:19000753
NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
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Prkcd
protein kinase C, delta
increases expression
ISO
Vanadium results in increased expression of PRKCD mRNA
CTD
PMID:19000753
NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
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Prkci
protein kinase C, iota
affects localization increases expression multiple interactions
ISO
Vanadium affects the localization of PRKCI protein Vanadium results in increased expression of PRKCI mRNA PRKCI protein mutant form inhibits the reaction [Vanadium results in increased phosphorylation of and results in increased activity of AKT1 protein]
CTD
PMID:14971662 PMID:19000753
NCBI chr 2:112,321,919...112,382,305
Ensembl chr 2:112,321,929...112,382,352
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Prkcq
protein kinase C, theta
decreases expression
ISO
Vanadium results in decreased expression of PRKCQ mRNA
CTD
PMID:19000753
NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704
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Prkcz
protein kinase C, zeta
affects localization
ISO
Vanadium affects the localization of PRKCZ protein
CTD
PMID:14971662
NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
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Prkd1
protein kinase D1
decreases expression
ISO
Vanadium results in decreased expression of PRKD1 mRNA
CTD
PMID:19000753
NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042
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Prkg1
protein kinase cGMP-dependent 1
decreases expression
ISO
Vanadium results in decreased expression of PRKG1 mRNA
CTD
PMID:19000753
NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080
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Prkg2
protein kinase cGMP-dependent 2
decreases expression
ISO
Vanadium results in decreased expression of PRKG2 mRNA
CTD
PMID:19000753
NCBI chr14:10,559,882...10,668,479
Ensembl chr14:10,559,882...10,666,888
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Ptgs1
prostaglandin-endoperoxide synthase 1
multiple interactions
ISO
[Vanadates results in increased abundance of Vanadium] which results in decreased expression of PTGS1 protein
CTD
PMID:25398544
NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
G
Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
ISO
[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide co-treated with [Vanadates results in increased abundance of Vanadium]] results in increased expression of PTGS2 protein
CTD
PMID:25398544
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Ptk2b
protein tyrosine kinase 2 beta
decreases expression
ISO
Vanadium results in decreased expression of PTK2B mRNA
CTD
PMID:19000753
NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
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Ptk6
protein tyrosine kinase 6
decreases expression
ISO
Vanadium results in decreased expression of PTK6 mRNA
CTD
PMID:19000753
NCBI chr 3:168,307,073...168,315,664
Ensembl chr 3:168,307,073...168,315,664
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Rps6kb1
ribosomal protein S6 kinase B1
multiple interactions
ISO
PRKCA protein affects the reaction [Vanadium results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]; Vanadium results in increased phosphorylation of and results in increased activity of RPS6KB1 protein
CTD
PMID:14971662
NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
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S1pr4
sphingosine-1-phosphate receptor 4
increases expression
ISO
Vanadium results in increased expression of S1PR4 mRNA
CTD
PMID:19000753
NCBI chr 7:8,207,767...8,210,043
Ensembl chr 7:8,208,098...8,211,893
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Scn10a
sodium voltage-gated channel alpha subunit 10
increases expression
ISO
Vanadium results in increased expression of SCN10A mRNA
CTD
PMID:19000753
NCBI chr 8:119,350,723...119,462,882
Ensembl chr 8:119,350,724...119,462,614
G
Slc11a2
solute carrier family 11 member 2
decreases expression multiple interactions
EXP
Vanadium results in decreased expression of SLC11A2 mRNA; Vanadium results in decreased expression of SLC11A2 protein Metals inhibits the reaction [SLC11A2 protein results in increased transport of Vanadium]
CTD
PMID:15908475
NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
G
Slc12a2
solute carrier family 12 member 2
increases expression
ISO
Vanadium results in increased expression of SLC12A2 mRNA
CTD
PMID:19000753
NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440
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Slc12a7
solute carrier family 12 member 7
decreases expression
ISO
Vanadium results in decreased expression of SLC12A7 mRNA
CTD
PMID:19000753
NCBI chr 1:29,472,692...29,554,246
Ensembl chr 1:29,472,692...29,554,302
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Slc13a2
solute carrier family 13 member 2
decreases expression
ISO
Vanadium results in decreased expression of SLC13A2 mRNA
CTD
PMID:19000753
NCBI chr10:63,291,813...63,319,127
Ensembl chr10:63,291,815...63,319,127
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Slc14a2
solute carrier family 14 member 2
increases expression
ISO
Vanadium results in increased expression of SLC14A2 mRNA
CTD
PMID:19000753
NCBI chr18:71,612,460...72,039,462
Ensembl chr18:71,612,460...71,792,968
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Slc15a1
solute carrier family 15 member 1
decreases expression
ISO
Vanadium results in decreased expression of SLC15A1 mRNA
CTD
PMID:19000753
NCBI chr15:98,537,641...98,582,544
Ensembl chr15:98,537,641...98,582,545
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Slc16a5
solute carrier family 16 member 5
increases expression
ISO
Vanadium results in increased expression of SLC16A5 mRNA
CTD
PMID:19000753
NCBI chr10:100,707,434...100,721,338
Ensembl chr10:100,707,434...100,721,338
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Slc17a5
solute carrier family 17 member 5
increases expression
ISO
Vanadium results in increased expression of SLC17A5 mRNA
CTD
PMID:19000753
NCBI chr 8:79,394,416...79,429,387
G
Slc18a3
solute carrier family 18 member A3
multiple interactions decreases expression
EXP
Nicotine inhibits the reaction [Vanadium results in decreased expression of SLC18A3 protein]
CTD
PMID:22119111
NCBI chr16:7,713,630...7,716,491
G
Slc1a1
solute carrier family 1 member 1
decreases expression
ISO
Vanadium results in decreased expression of SLC1A1 mRNA
CTD
PMID:19000753
NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402
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Slc1a4
solute carrier family 1 member 4
decreases expression
ISO
Vanadium results in decreased expression of SLC1A4 mRNA
CTD
PMID:19000753
NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418
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Slc22a14
solute carrier family 22, member 14
increases expression
ISO
Vanadium results in increased expression of SLC22A14 mRNA
CTD
PMID:19000753
NCBI chr 8:118,894,537...118,916,416
Ensembl chr 8:118,895,259...118,908,255
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Slc23a1
solute carrier family 23 member 1
increases expression
ISO
Vanadium results in increased expression of SLC23A1 mRNA
CTD
PMID:19000753
NCBI chr18:27,214,940...27,230,564
Ensembl chr18:27,216,281...27,230,697
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Slc2a4
solute carrier family 2 member 4
decreases expression
ISO
Vanadium results in decreased expression of SLC2A4 mRNA
CTD
PMID:19000753
NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
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Slc30a3
solute carrier family 30 member 3
decreases expression
ISO
Vanadium results in decreased expression of SLC30A3 mRNA
CTD
PMID:19000753
NCBI chr 6:25,264,310...25,284,720
Ensembl chr 6:25,275,528...25,284,720
G
Slc30a4
solute carrier family 30 member 4
decreases expression
ISO
Vanadium results in decreased expression of SLC30A4 mRNA
CTD
PMID:19000753
NCBI chr 3:109,753,270...109,775,306
Ensembl chr 3:109,753,273...109,775,306
G
Slc31a1
solute carrier family 31 member 1
decreases expression
ISO
Vanadium results in decreased expression of SLC31A1 mRNA
CTD
PMID:19000753
NCBI chr 5:75,814,744...75,844,241
Ensembl chr 5:75,814,743...75,844,228
G
Slc39a1
solute carrier family 39 member 1
decreases expression
ISO
Vanadium results in decreased expression of SLC39A1 mRNA
CTD
PMID:19000753
NCBI chr 2:175,703,413...175,709,063
Ensembl chr 2:175,703,441...175,709,058
G
Slc6a9
solute carrier family 6 member 9
decreases expression
ISO
Vanadium results in decreased expression of SLC6A9 mRNA
CTD
PMID:19000753
NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728
G
Slco2b1
solute carrier organic anion transporter family, member 2b1
increases expression
ISO
Vanadium results in increased expression of SLCO2B1 mRNA
CTD
PMID:19000753
NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353
G
Slco4a1
solute carrier organic anion transporter family, member 4a1
decreases expression
ISO
Vanadium results in decreased expression of SLCO4A1 mRNA
CTD
PMID:19000753
NCBI chr 3:167,559,177...167,578,307
Ensembl chr 3:167,559,316...167,578,305
G
Smarcd1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
decreases expression
ISO
Vanadium results in decreased expression of SMARCD1 mRNA
CTD
PMID:19000753
NCBI chr 7:130,829,783...130,840,323
Ensembl chr 7:130,829,768...130,840,323
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Stat3
signal transducer and activator of transcription 3
multiple interactions
EXP
Vanadium promotes the reaction [LEP protein results in increased phosphorylation of STAT3 protein]
CTD
PMID:16195403
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
G
Stk38
serine/threonine kinase 38
increases expression
ISO
Vanadium results in increased expression of STK38 mRNA
CTD
PMID:19000753
NCBI chr20:7,034,245...7,067,803
Ensembl chr20:7,034,242...7,068,198
G
Tap2
transporter 2, ATP binding cassette subfamily B member
increases expression
ISO
Vanadium results in increased expression of TAP2 mRNA
CTD
PMID:19000753
NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407
G
Tbxas1
thromboxane A synthase 1
decreases expression
ISO
Vanadium results in decreased expression of TBXAS1 mRNA
CTD
PMID:19000753
NCBI chr 4:67,664,963...67,837,096
Ensembl chr 4:67,665,007...67,837,096
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Timp1
TIMP metallopeptidase inhibitor 1
decreases expression
ISO
Vanadium results in decreased expression of TIMP1 mRNA
CTD
PMID:19000753
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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Tnf
tumor necrosis factor
multiple interactions
ISO EXP
[Titanium co-treated with Vanadium co-treated with Aluminum] results in increased expression of TNF mRNA [Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] inhibits the reaction [Streptozocin results in increased expression of TNF protein]
CTD
PMID:15862027 PMID:17408380
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tp53
tumor protein p53
multiple interactions increases activity
EXP ISO
Vanadium inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of TP53 protein]; Vanadium promotes the reaction [2-Acetylaminofluorene results in increased expression of TP53 protein] Vanadium results in increased activity of TP53 protein
CTD
PMID:15565650 PMID:18155637 PMID:19000753
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Troap
trophinin associated protein
increases expression
ISO
Vanadium results in increased expression of TROAP mRNA
CTD
PMID:19000753
NCBI chr 7:130,233,534...130,242,369
Ensembl chr 7:130,234,544...130,242,365
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Ucp1
uncoupling protein 1
multiple interactions
EXP
Vanadium promotes the reaction [LEP protein results in increased expression of UCP1 protein]
CTD
PMID:16195403
NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852
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Usf1
upstream transcription factor 1
increases activity
ISO
Vanadium results in increased activity of USF1 protein
CTD
PMID:19000753
NCBI chr13:83,845,230...83,854,875
Ensembl chr13:83,822,035...83,854,885
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Vcam1
vascular cell adhesion molecule 1
multiple interactions
ISO
[Particulate Matter results in increased abundance of Vanadium] which results in increased expression of VCAM1 protein
CTD
PMID:26732377
NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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Vdac2
voltage-dependent anion channel 2
increases expression
ISO
Vanadium results in increased expression of VDAC2 mRNA
CTD
PMID:19000753
NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553
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Vegfd
vascular endothelial growth factor D
increases expression
ISO
Vanadium results in increased expression of VEGFD mRNA
CTD
PMID:19000753
NCBI chr X:30,073,122...30,108,413
Ensembl chr X:30,074,163...30,108,295
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Zap70
zeta chain of T cell receptor associated protein kinase 70
decreases expression
ISO
Vanadium results in decreased expression of ZAP70 mRNA
CTD
PMID:19000753
NCBI chr 9:38,989,750...39,011,701
Ensembl chr 9:38,989,750...39,011,700
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Abcc5
ATP binding cassette subfamily C member 5
affects expression
ISO
vanadium pentoxide affects the expression of ABCC5 mRNA
CTD
PMID:26210822
NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
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Adcy2
adenylate cyclase 2
affects expression
ISO
vanadium pentoxide affects the expression of ADCY2 mRNA
CTD
PMID:26210822
NCBI chr 1:34,375,639...34,822,252
Ensembl chr 1:34,375,895...34,822,236
G
Adcy3
adenylate cyclase 3
affects expression
ISO
vanadium pentoxide affects the expression of ADCY3 mRNA
CTD
PMID:26210822
NCBI chr 6:27,100,089...27,203,686
Ensembl chr 6:27,124,828...27,203,686
G
Adcy4
adenylate cyclase 4
affects expression
ISO
vanadium pentoxide affects the expression of ADCY4 mRNA
CTD
PMID:26210822
NCBI chr15:29,266,280...29,282,153
Ensembl chr15:29,266,287...29,282,108
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Adcy7
adenylate cyclase 7
affects expression
ISO
vanadium pentoxide affects the expression of ADCY7 mRNA
CTD
PMID:26210822
NCBI chr19:18,740,875...18,798,924
Ensembl chr19:18,740,875...18,776,311
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Adcy8
adenylate cyclase 8
affects expression
ISO
vanadium pentoxide affects the expression of ADCY8 mRNA
CTD
PMID:26210822
NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911
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Arsj
arylsulfatase family, member J
affects expression
ISO
vanadium pentoxide affects the expression of ARSJ mRNA
CTD
PMID:26210822
NCBI chr 2:214,774,631...214,854,614
Ensembl chr 2:214,774,654...214,854,612
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Bmp2
bone morphogenetic protein 2
affects expression
ISO
vanadium pentoxide affects the expression of BMP2 mRNA
CTD
PMID:17459161
NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
G
Btg1
BTG anti-proliferation factor 1
decreases expression
ISO
vanadium pentoxide results in decreased expression of BTG1 mRNA
CTD
PMID:17459161
NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649
G
Btg2
BTG anti-proliferation factor 2
decreases expression
ISO
vanadium pentoxide results in decreased expression of BTG2 mRNA
CTD
PMID:17459161
NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
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Casp3
caspase 3
multiple interactions increases activity
EXP
PRKCD mutant form inhibits the reaction [vanadium pentoxide results in increased activity of CASP3 protein]
CTD
PMID:19646462
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp9
caspase 9
increases activity
EXP
vanadium pentoxide results in increased activity of CASP9 protein
CTD
PMID:19646462
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Ccn2
cellular communication network factor 2
decreases expression
ISO
vanadium pentoxide results in decreased expression of CCN2 mRNA
CTD
PMID:17459161
NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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Ccng2
cyclin G2
decreases expression
ISO
vanadium pentoxide results in decreased expression of CCNG2 mRNA
CTD
PMID:17459161
NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
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Ccnt2
cyclin T2
affects expression
ISO
vanadium pentoxide affects the expression of CCNT2 mRNA
CTD
PMID:17459161
NCBI chr13:39,251,573...39,293,172
Ensembl chr13:39,251,573...39,292,019
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Cd44
CD44 molecule
affects expression
ISO
vanadium pentoxide affects the expression of CD44 mRNA
CTD
PMID:17459161 PMID:26210822
NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
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Cdc25c
cell division cycle 25C
increases expression
ISO
vanadium pentoxide results in increased expression of CDC25C protein
CTD
PMID:33913241
NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
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Cdh1
cadherin 1
decreases expression
ISO
vanadium pentoxide results in decreased expression of CDH1 protein
CTD
PMID:38479551
NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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Cdk7
cyclin-dependent kinase 7
decreases expression
ISO
vanadium pentoxide results in decreased expression of CDK7 mRNA
CTD
PMID:17459161
NCBI chr 2:31,840,558...31,865,422
Ensembl chr 2:31,840,558...31,865,383
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Cdk9
cyclin-dependent kinase 9
decreases expression
ISO
vanadium pentoxide results in decreased expression of CDK9 mRNA
CTD
PMID:17459161
NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
decreases expression
ISO
vanadium pentoxide results in decreased expression of CDKN1A protein
CTD
PMID:33913241
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Cdkn1b
cyclin-dependent kinase inhibitor 1B
decreases expression
ISO
vanadium pentoxide results in decreased expression of CDKN1B mRNA
CTD
PMID:17459161
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
G
Cdkn1c
cyclin-dependent kinase inhibitor 1C
decreases expression
ISO
vanadium pentoxide results in decreased expression of CDKN1C mRNA
CTD
PMID:17459161
NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
G
Cdkn2c
cyclin-dependent kinase inhibitor 2C
decreases expression
ISO
vanadium pentoxide results in decreased expression of CDKN2C mRNA
CTD
PMID:17459161
NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
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Col1a1
collagen type I alpha 1 chain
decreases expression
ISO
vanadium pentoxide results in decreased expression of COL1A1 mRNA
CTD
PMID:17459161
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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Col1a2
collagen type I alpha 2 chain
decreases expression
ISO
vanadium pentoxide results in decreased expression of COL1A2 mRNA
CTD
PMID:17459161
NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
G
Col3a1
collagen type III alpha 1 chain
decreases expression
ISO
vanadium pentoxide results in decreased expression of COL3A1 mRNA
CTD
PMID:17459161
NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
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Ctsa
cathepsin A
affects expression
ISO
vanadium pentoxide affects the expression of CTSA mRNA
CTD
PMID:26210822
NCBI chr 3:153,569,106...153,574,983
Ensembl chr 3:153,568,381...153,576,215
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Cx3cr1
C-X3-C motif chemokine receptor 1
increases expression
ISO
vanadium pentoxide results in increased expression of CX3CR1 mRNA
CTD
PMID:17459161
NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
G
Cxcl1
C-X-C motif chemokine ligand 1
increases expression
EXP
vanadium pentoxide results in increased expression of CXCL1 protein
CTD
PMID:9707512
NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
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Cxcl10
C-X-C motif chemokine ligand 10
multiple interactions increases expression
ISO
acetovanillone inhibits the reaction [vanadium pentoxide results in increased expression of CXCL10 mRNA]; Allopurinol inhibits the reaction [vanadium pentoxide results in increased expression of CXCL10 mRNA]
CTD
PMID:17459161 PMID:18322232
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
G
Cxcl2
C-X-C motif chemokine ligand 2
increases expression
ISO
vanadium pentoxide results in increased expression of CXCL2 protein
CTD
PMID:9707512
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
G
Cxcl9
C-X-C motif chemokine ligand 9
increases expression
ISO
vanadium pentoxide results in increased expression of CXCL9 mRNA
CTD
PMID:17459161
NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
G
Dusp6
dual specificity phosphatase 6
affects expression
ISO
vanadium pentoxide affects the expression of DUSP6 mRNA
CTD
PMID:17459161
NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
G
Egr1
early growth response 1
affects expression
ISO
vanadium pentoxide affects the expression of EGR1 mRNA
CTD
PMID:17459161
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
G
Egr3
early growth response 3
affects expression
ISO
vanadium pentoxide affects the expression of EGR3 mRNA
CTD
PMID:17459161
NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627
G
Fabp4
fatty acid binding protein 4
decreases expression
ISO
vanadium pentoxide results in decreased expression of FABP4 mRNA
CTD
PMID:26210822
NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
G
Fgf2
fibroblast growth factor 2
decreases expression
ISO
vanadium pentoxide results in decreased expression of FGF2 mRNA
CTD
PMID:17459161
NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
G
Fgf9
fibroblast growth factor 9
decreases expression
ISO
vanadium pentoxide results in decreased expression of FGF9 mRNA
CTD
PMID:17459161
NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309
G
Galc
galactosylceramidase
affects expression
ISO
vanadium pentoxide affects the expression of GALC mRNA
CTD
PMID:26210822
NCBI chr 6:117,452,888...117,522,281
Ensembl chr 6:117,452,895...117,515,830
G
Gas1
growth arrest-specific 1
decreases expression
ISO
vanadium pentoxide results in decreased expression of GAS1 mRNA
CTD
PMID:17459161
NCBI chr17:4,482,168...4,485,153
G
Gata6
GATA binding protein 6
affects expression
ISO
vanadium pentoxide affects the expression of GATA6 mRNA
CTD
PMID:17459161
NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532
G
Gbp1
guanylate binding protein 1
affects expression
ISO
vanadium pentoxide affects the expression of GBP1 mRNA
CTD
PMID:17459161
NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131 Ensembl chr 2:231,398,163...231,432,131
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Gdf15
growth differentiation factor 15
increases expression
ISO
vanadium pentoxide results in increased expression of GDF15 mRNA
CTD
PMID:17459161
NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
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Gusb
glucuronidase, beta
affects expression
ISO
vanadium pentoxide affects the expression of GUSB mRNA
CTD
PMID:26210822
NCBI chr12:26,701,188...26,714,718
Ensembl chr12:26,697,951...26,726,905
G
Hbegf
heparin-binding EGF-like growth factor
multiple interactions increases expression
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [vanadium pentoxide results in increased expression of HBEGF mRNA]; Acetylcysteine inhibits the reaction [vanadium pentoxide results in increased expression of HBEGF mRNA]; RTKI cpd inhibits the reaction [vanadium pentoxide results in increased expression of HBEGF mRNA]; SB 203580 inhibits the reaction [vanadium pentoxide results in increased expression of HBEGF mRNA] vanadium pentoxide results in increased expression of HBEGF mRNA; vanadium pentoxide results in increased expression of HBEGF protein
CTD
PMID:11159045 PMID:12676768 PMID:17459161
NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
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Hexa
hexosaminidase subunit alpha
affects expression
ISO
vanadium pentoxide affects the expression of HEXA mRNA
CTD
PMID:26210822
NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013
G
Hgf
hepatocyte growth factor
increases expression
ISO
vanadium pentoxide results in increased expression of HGF mRNA
CTD
PMID:17459161
NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
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Hyal2
hyaluronidase 2
affects expression
ISO
vanadium pentoxide affects the expression of HYAL2 mRNA
CTD
PMID:26210822
NCBI chr 8:108,241,895...108,246,853
Ensembl chr 8:108,243,133...108,246,850
G
Ifnb1
interferon beta 1
multiple interactions increases expression
ISO
acetovanillone inhibits the reaction [vanadium pentoxide results in increased expression of IFNB1 mRNA]; Allopurinol inhibits the reaction [vanadium pentoxide results in increased expression of IFNB1 mRNA]; IFNB1 protein affects the reaction [vanadium pentoxide results in increased activity of STAT1 protein]
CTD
PMID:18322232
NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523
G
Ifngr1
interferon gamma receptor 1
decreases expression
ISO
vanadium pentoxide results in decreased expression of IFNGR1 mRNA
CTD
PMID:17459161
NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785
G
Il15
interleukin 15
decreases expression
ISO
vanadium pentoxide results in decreased expression of IL15 mRNA
CTD
PMID:17459161
NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820
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Il6
interleukin 6
increases expression
ISO
vanadium pentoxide results in increased expression of IL6 mRNA
CTD
PMID:17459161
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Irf1
interferon regulatory factor 1
affects expression
ISO
vanadium pentoxide affects the expression of IRF1 mRNA
CTD
PMID:17459161
NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
G
Jak1
Janus kinase 1
multiple interactions
ISO
JAK1 protein affects the reaction [vanadium pentoxide results in increased activity of STAT1 protein]
CTD
PMID:18322232
NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
G
Jak2
Janus kinase 2
decreases expression
ISO
vanadium pentoxide results in decreased expression of JAK2 mRNA
CTD
PMID:17459161
NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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Jun
Jun proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
vanadium pentoxide results in increased expression of JUN mRNA
CTD
PMID:17459161
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
G
Keap1
Kelch-like ECH-associated protein 1
decreases expression
ISO
vanadium pentoxide results in decreased expression of KEAP1 mRNA
CTD
PMID:17459161
NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
G
Klf7
KLF transcription factor 7
increases expression
ISO
vanadium pentoxide results in increased expression of KLF7 mRNA
CTD
PMID:17459161
NCBI chr 9:65,433,683...65,526,372
Ensembl chr 9:65,437,167...65,526,261
G
Lyst
lysosomal trafficking regulator
affects expression
ISO
vanadium pentoxide affects the expression of LYST mRNA
CTD
PMID:17459161
NCBI chr17:86,241,384...86,443,501
Ensembl chr17:86,241,384...86,443,480
G
Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
affects expression
ISO
vanadium pentoxide affects the expression of LYVE1 mRNA
CTD
PMID:26210822
NCBI chr 1:164,962,872...164,976,309
Ensembl chr 1:164,962,872...164,976,309
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Mapk1
mitogen activated protein kinase 1
increases phosphorylation increases activity
ISO
vanadium pentoxide results in increased phosphorylation of MAPK1 protein vanadium pentoxide results in increased activity of MAPK1 protein
CTD
PMID:12376484 PMID:12676768
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
G
Mapk3
mitogen activated protein kinase 3
increases phosphorylation increases activity
ISO
vanadium pentoxide results in increased phosphorylation of MAPK3 protein vanadium pentoxide results in increased activity of MAPK3 protein
CTD
PMID:12376484 PMID:12676768
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Marcks
myristoylated alanine rich protein kinase C substrate
decreases expression
ISO
vanadium pentoxide results in decreased expression of MARCKS mRNA
CTD
PMID:17459161
NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
G
Mmp2
matrix metallopeptidase 2
increases expression
ISO
vanadium pentoxide results in increased expression of MMP2 protein
CTD
PMID:18059072
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
G
Mmp9
matrix metallopeptidase 9
increases expression
ISO
vanadium pentoxide results in increased expression of MMP9 protein
CTD
PMID:18059072
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
G
Mtch1
mitochondrial carrier 1
affects expression
ISO
vanadium pentoxide affects the expression of MTCH1 mRNA
CTD
PMID:26210822
NCBI chr20:7,389,942...7,413,426
Ensembl chr20:7,389,949...7,413,426
G
Nampt
nicotinamide phosphoribosyltransferase
increases expression
ISO
vanadium pentoxide results in increased expression of NAMPT mRNA
CTD
PMID:17459161
NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
G
Nedd9
neural precursor cell expressed, developmentally down-regulated 9
affects expression
ISO
vanadium pentoxide affects the expression of NEDD9 mRNA
CTD
PMID:17459161
NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019
G
Neurl1
neuralized E3 ubiquitin protein ligase 1
affects expression
ISO
vanadium pentoxide affects the expression of NEURL1A mRNA
CTD
PMID:26210822
NCBI chr 1:246,066,830...246,152,890
Ensembl chr 1:246,067,100...246,152,903
G
Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression
ISO
vanadium pentoxide results in increased expression of NQO1 mRNA
CTD
PMID:17459161
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
G
Oxr1
oxidation resistance 1
decreases expression
ISO
vanadium pentoxide results in decreased expression of OXR1 mRNA
CTD
PMID:17459161
NCBI chr 7:72,528,750...72,965,666
Ensembl chr 7:72,528,786...72,965,666
G
Oxsr1
oxidative stress responsive kinase 1
decreases expression
ISO
vanadium pentoxide results in decreased expression of OXSR1 mRNA
CTD
PMID:17459161
NCBI chr 8:118,972,754...119,062,102
Ensembl chr 8:118,972,754...119,062,027
G
Pdgfa
platelet derived growth factor subunit A
increases expression
EXP
vanadium pentoxide results in increased expression of PDGFA mRNA
CTD
PMID:17134509
NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
G
Pdgfb
platelet derived growth factor subunit B
increases expression
EXP
vanadium pentoxide results in increased expression of PDGFB mRNA
CTD
PMID:17134509
NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
G
Pdgfc
platelet derived growth factor C
increases expression
EXP
vanadium pentoxide results in increased expression of PDGFC mRNA
CTD
PMID:17134509
NCBI chr 2:166,316,870...166,493,449
Ensembl chr 2:166,316,803...166,493,433
G
Pdgfra
platelet derived growth factor receptor alpha
increases expression
EXP
vanadium pentoxide results in increased expression of PDGFRA mRNA
CTD
PMID:17134509
NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
G
Pipox
pipecolic acid and sarcosine oxidase
increases expression
ISO
vanadium pentoxide results in increased expression of PIPOX mRNA
CTD
PMID:17459161
NCBI chr10:62,769,874...62,783,484
Ensembl chr10:62,769,900...62,782,370
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Plpp1
phospholipid phosphatase 1
affects expression
ISO
vanadium pentoxide affects the expression of PPAP2A mRNA
CTD
PMID:26210822
NCBI chr 2:44,439,002...44,500,430
Ensembl chr 2:44,438,994...44,501,268
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Plpp3
phospholipid phosphatase 3
affects expression
ISO
vanadium pentoxide affects the expression of PLPP3 mRNA
CTD
PMID:26210822
NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205
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Prkcd
protein kinase C, delta
multiple interactions increases expression
EXP ISO
PRKCD mutant form inhibits the reaction [vanadium pentoxide results in increased activity of CASP3 protein]; vanadium pentoxide results in increased cleavage of and results in increased activity of PRKCD protein vanadium pentoxide results in increased expression of PRKCD mRNA
CTD
PMID:19646462 PMID:26210822
NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
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Prkce
protein kinase C, epsilon
affects expression
ISO
vanadium pentoxide affects the expression of PRKCE mRNA
CTD
PMID:26210822
NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
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Sgpl1
sphingosine-1-phosphate lyase 1
affects expression
ISO
vanadium pentoxide affects the expression of SGPL1 mRNA
CTD
PMID:26210822
NCBI chr20:29,047,793...29,094,209
Ensembl chr20:29,047,796...29,094,084
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Slc11a2
solute carrier family 11 member 2
increases expression
EXP
vanadium pentoxide results in increased expression of SLC11A2 protein
CTD
PMID:19646462
NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
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Slc2a3
solute carrier family 2 member 3
affects expression
ISO
vanadium pentoxide affects the expression of SLC2A3 mRNA
CTD
PMID:17459161
NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472
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Slc2a4
solute carrier family 2 member 4
decreases expression
ISO
vanadium pentoxide results in decreased expression of SLC2A4 mRNA
CTD
PMID:26210822
NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
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Smad1
SMAD family member 1
decreases expression
ISO
vanadium pentoxide results in decreased expression of SMAD1 mRNA
CTD
PMID:17459161
NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651
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Smurf1
SMAD specific E3 ubiquitin protein ligase 1
decreases expression
ISO
vanadium pentoxide results in decreased expression of SMURF1 mRNA
CTD
PMID:17459161
NCBI chr12:9,635,009...9,726,520
Ensembl chr12:9,635,025...9,726,519
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Socs1
suppressor of cytokine signaling 1
decreases expression
ISO
vanadium pentoxide results in decreased expression of SOCS1 mRNA
CTD
PMID:17459161
NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
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Socs3
suppressor of cytokine signaling 3
increases expression
ISO
vanadium pentoxide results in increased expression of SOCS3 mRNA
CTD
PMID:17459161
NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
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Sod2
superoxide dismutase 2
increases expression
ISO
vanadium pentoxide results in increased expression of SOD2 mRNA
CTD
PMID:17459161
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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Sphk1
sphingosine kinase 1
affects expression
ISO
vanadium pentoxide affects the expression of SPHK1 mRNA
CTD
PMID:26210822
NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240
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Spp1
secreted phosphoprotein 1
increases expression
EXP
vanadium pentoxide results in increased expression of SPP1 mRNA
CTD
PMID:17134509
NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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Spred2
sprouty-related, EVH1 domain containing 2
affects expression
ISO
vanadium pentoxide affects the expression of SPRED2 mRNA
CTD
PMID:17459161
NCBI chr14:94,149,210...94,250,787
Ensembl chr14:94,148,837...94,249,162
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Sptlc2
serine palmitoyltransferase, long chain base subunit 2
affects expression
ISO
vanadium pentoxide affects the expression of SPTLC2 mRNA
CTD
PMID:26210822
NCBI chr 6:106,948,682...107,031,532
Ensembl chr 6:106,950,949...107,031,542
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Stat1
signal transducer and activator of transcription 1
multiple interactions decreases expression
ISO
acetovanillone inhibits the reaction [vanadium pentoxide results in increased phosphorylation of STAT1 protein]; Allopurinol inhibits the reaction [vanadium pentoxide results in increased phosphorylation of STAT1 protein]; Hydrogen Peroxide affects the reaction [vanadium pentoxide results in increased phosphorylation of and results in increased activity of STAT1 protein]; IFNB1 protein affects the reaction [vanadium pentoxide results in increased activity of STAT1 protein]; JAK1 protein affects the reaction [vanadium pentoxide results in increased activity of STAT1 protein]; vanadium pentoxide results in increased activity of and results in increased phosphorylation of STAT1 protein vanadium pentoxide results in decreased expression of STAT1 mRNA
CTD
PMID:17459161 PMID:18322232
NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
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Stc1
stanniocalcin 1
increases expression
ISO
vanadium pentoxide results in increased expression of STC1 mRNA
CTD
PMID:17459161
NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264
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Tf
transferrin
increases expression
EXP
vanadium pentoxide results in increased expression of TF protein
CTD
PMID:19646462
NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
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Tgfb2
transforming growth factor, beta 2
decreases expression
ISO
vanadium pentoxide results in decreased expression of TGFB2 mRNA
CTD
PMID:17459161
NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
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Tnf
tumor necrosis factor
increases expression
ISO
vanadium pentoxide results in increased expression of TNF protein
CTD
PMID:9707512
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Traf4
Tnf receptor associated factor 4
decreases expression
ISO
vanadium pentoxide results in decreased expression of TRAF4 mRNA
CTD
PMID:17459161
NCBI chr10:63,054,169...63,060,284
Ensembl chr10:63,054,181...63,060,284
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Ucp1
uncoupling protein 1
decreases expression
ISO
vanadium pentoxide results in decreased expression of UCP1 mRNA
CTD
PMID:26210822
NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852
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Vcam1
vascular cell adhesion molecule 1
decreases expression
ISO
vanadium pentoxide results in decreased expression of VCAM1 mRNA
CTD
PMID:17459161
NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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Vegfa
vascular endothelial growth factor A
increases expression
ISO
vanadium pentoxide results in increased expression of VEGFA mRNA
CTD
PMID:17459161
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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Slc6a4
solute carrier family 6 member 4
increases activity
EXP
sodium vanadate increases activity of Slc6a4 protein in synaptosomes trisodium vanadate increases activity of Slc6a4 protein in cultured neurons
RGD
PMID:12590935 PMID:11859926
RGD:38549585 , RGD:38549589
NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
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Cdc25c
cell division cycle 25C
increases expression
ISO
vanadium dioxide results in increased expression of CDC25C protein
CTD
PMID:33913241
NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
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Slc11a2
solute carrier family 11 member 2
increases transport
ISO
SLC11A2 protein results in increased transport of vanadium dioxide
CTD
PMID:22736759
NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
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Tp53
tumor protein p53
increases expression
ISO
vanadium dioxide results in increased expression of TP53 protein
CTD
PMID:33913241
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Abl1
ABL proto-oncogene 1, non-receptor tyrosine kinase
increases expression
ISO
Vanadium results in increased expression of ABL1 mRNA
CTD
PMID:19000753
NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
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Aco1
aconitase 1
increases activity
ISO
Vanadium results in increased activity of ACO1 protein
CTD
PMID:16386771
NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
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Adam17
ADAM metallopeptidase domain 17
increases expression
ISO
Vanadium results in increased expression of ADAM17 mRNA
CTD
PMID:19000753
NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
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Adamts4
ADAM metallopeptidase with thrombospondin type 1 motif, 4
decreases expression
ISO
Vanadium results in decreased expression of ADAMTS4 mRNA
CTD
PMID:19000753
NCBI chr13:83,670,556...83,680,045
Ensembl chr13:83,670,183...83,680,065
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Adipoq
adiponectin, C1Q and collagen domain containing
multiple interactions
ISO
NL-71-101 inhibits the reaction [Vanadium results in increased expression of ADIPOQ protein]; Vanadium results in increased expression of and results in increased secretion of ADIPOQ protein
CTD
PMID:16524741
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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Ahr
aryl hydrocarbon receptor
multiple interactions
ISO
Vanadium inhibits the reaction [[AHR protein binds to ARNT protein] which binds to CYP1A1 promoter] Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]
CTD
PMID:18541696 PMID:23423713
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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Akt1
AKT serine/threonine kinase 1
multiple interactions
ISO
PRKCA protein affects the reaction [Vanadium results in increased phosphorylation of and results in increased activity of AKT1 protein]; PRKCI protein mutant form inhibits the reaction [Vanadium results in increased phosphorylation of and results in increased activity of AKT1 protein]; Vanadium results in increased phosphorylation of and results in increased activity of AKT1 protein
CTD
PMID:14971662
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Alk
ALK receptor tyrosine kinase
decreases expression
ISO
Vanadium results in decreased expression of ALK mRNA
CTD
PMID:19000753
NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034
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Aoc3
amine oxidase, copper containing 3
decreases expression
ISO
Vanadium results in decreased expression of AOC3 mRNA
CTD
PMID:19000753
NCBI chr10:86,272,757...86,280,702
G
Arnt
aryl hydrocarbon receptor nuclear translocator
multiple interactions
ISO
Vanadium inhibits the reaction [[AHR protein binds to ARNT protein] which binds to CYP1A1 promoter]
CTD
PMID:18541696
NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
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Atp1b4
ATPase Na+/K+ transporting family member beta 4
decreases expression
ISO
Vanadium results in decreased expression of ATP1B4 mRNA
CTD
PMID:19000753
NCBI chr X:117,087,284...117,108,023
Ensembl chr X:117,057,423...117,108,020
G
Atp2a3
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
increases expression
ISO
Vanadium results in increased expression of ATP2A3 mRNA
CTD
PMID:19000753
NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748
G
Atp2b1
ATPase plasma membrane Ca2+ transporting 1
increases expression
ISO
Vanadium results in increased expression of ATP2B1 mRNA
CTD
PMID:19000753
NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295
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Atp2b2
ATPase plasma membrane Ca2+ transporting 2
increases expression
ISO
Vanadium results in increased expression of ATP2B2 mRNA
CTD
PMID:19000753
NCBI chr 4:146,894,602...147,208,060
Ensembl chr 4:146,896,332...147,140,665
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Atp5f1b
ATP synthase F1 subunit beta
increases expression
ISO
Vanadium results in increased expression of ATP5F1B mRNA
CTD
PMID:19000753
NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
G
Atp5mf
ATP synthase membrane subunit f
increases expression
ISO
Vanadium results in increased expression of ATP5MF mRNA
CTD
PMID:19000753
NCBI chr12:9,421,665...9,428,236
Ensembl chr12:9,421,579...9,428,236
G
Atp5mg
ATP synthase membrane subunit G
increases expression
ISO
Vanadium results in increased expression of ATP5MG mRNA
CTD
PMID:19000753
NCBI chr 8:45,225,680...45,233,630
Ensembl chr 8:45,225,686...45,233,559
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Atp5po
ATP synthase peripheral stalk subunit OSCP
increases expression
ISO
Vanadium results in increased expression of ATP5PO mRNA
CTD
PMID:19000753
NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592
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Atp6ap1
ATPase H+ transporting accessory protein 1
decreases expression
ISO
Vanadium results in decreased expression of ATP6AP1 mRNA
CTD
PMID:19000753
NCBI chr X:152,079,954...152,087,034
Ensembl chr X:152,079,865...152,087,034
G
Atp6ap2
ATPase H+ transporting accessory protein 2
increases expression
ISO
Vanadium results in increased expression of ATP6AP2 mRNA
CTD
PMID:19000753
NCBI chr X:10,183,983...10,210,948
Ensembl chr X:10,183,068...10,210,918
G
Atp6v0b
ATPase H+ transporting V0 subunit B
decreases expression
ISO
Vanadium results in decreased expression of ATP6V0B mRNA
CTD
PMID:19000753
NCBI chr 5:131,423,384...131,424,900
Ensembl chr 5:131,423,387...131,426,401
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Atp6v0c
ATPase H+ transporting V0 subunit C
decreases expression
ISO
Vanadium results in decreased expression of ATP6V0C mRNA
CTD
PMID:19000753
NCBI chr10:13,196,204...13,202,580
Ensembl chr10:13,196,204...13,201,500
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Atp6v1a
ATPase H+ transporting V1 subunit A
increases expression
ISO
Vanadium results in increased expression of ATP6V1A mRNA
CTD
PMID:19000753
NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
G
Bmx
BMX non-receptor tyrosine kinase
decreases expression
ISO
Vanadium results in decreased expression of BMX mRNA
CTD
PMID:19000753
NCBI chr X:30,227,251...30,290,015
Ensembl chr X:30,227,251...30,289,993
G
Braf
B-Raf proto-oncogene, serine/threonine kinase
decreases expression
ISO
Vanadium results in decreased expression of BRAF mRNA
CTD
PMID:19000753
NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
G
Cacna1f
calcium voltage-gated channel subunit alpha1 F
increases expression
ISO
Vanadium results in increased expression of CACNA1F mRNA
CTD
PMID:19000753
NCBI chr X:14,868,096...14,896,413
Ensembl chr X:14,868,024...14,896,413
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Cacna2d2
calcium voltage-gated channel auxiliary subunit alpha2delta 2
increases expression
ISO
Vanadium results in increased expression of CACNA2D2 mRNA
CTD
PMID:19000753
NCBI chr 8:108,072,208...108,203,516
Ensembl chr 8:108,072,454...108,203,173
G
Cacnb1
calcium voltage-gated channel auxiliary subunit beta 1
decreases expression
ISO
Vanadium results in decreased expression of CACNB1 mRNA
CTD
PMID:19000753
NCBI chr10:82,998,182...83,018,838
Ensembl chr10:82,998,182...83,018,694
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Cacng4
calcium voltage-gated channel auxiliary subunit gamma 4
decreases expression
ISO
Vanadium results in decreased expression of CACNG4 mRNA
CTD
PMID:19000753
NCBI chr10:92,683,778...92,745,842
Ensembl chr10:92,683,761...92,746,126
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Camkk2
calcium/calmodulin-dependent protein kinase kinase 2
decreases expression
ISO
Vanadium results in decreased expression of CAMKK2 mRNA
CTD
PMID:19000753
NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279
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Cat
catalase
decreases activity multiple interactions
EXP
Vanadium results in decreased activity of CAT protein Testosterone Propionate inhibits the reaction [Vanadium results in decreased activity of CAT protein]
CTD
PMID:20521886
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Ccn1
cellular communication network factor 1
decreases expression
ISO
Vanadium results in decreased expression of CCN1 mRNA
CTD
PMID:19000753
NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
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Cd36
CD36 molecule
decreases expression
ISO
Vanadium results in decreased expression of CD36 mRNA
CTD
PMID:19000753
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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Cdk16
cyclin-dependent kinase 16
decreases expression
ISO
Vanadium results in decreased expression of CDK16 mRNA
CTD
PMID:19000753
NCBI chr X:1,492,814...1,504,309
Ensembl chr X:1,492,814...1,504,148
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Cdk17
cyclin-dependent kinase 17
decreases expression
ISO
Vanadium results in decreased expression of CDK17 mRNA
CTD
PMID:19000753
NCBI chr 7:27,683,890...27,765,814
Ensembl chr 7:27,683,890...27,764,910
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Cdk6
cyclin-dependent kinase 6
increases expression
ISO
Vanadium results in increased expression of CDK6 mRNA
CTD
PMID:19000753
NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
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Cdk8
cyclin-dependent kinase 8
decreases expression
ISO
Vanadium results in decreased expression of CDK8 mRNA
CTD
PMID:19000753
NCBI chr12:8,737,198...8,805,026
Ensembl chr12:8,737,262...8,804,177
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Chat
choline O-acetyltransferase
decreases expression multiple interactions
EXP
Vanadium results in decreased expression of CHAT protein Nicotine inhibits the reaction [Vanadium results in decreased expression of CHAT protein]
CTD
PMID:22119111
NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
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Clu
clusterin
increases expression
ISO
Vanadium results in increased expression of CLU mRNA
CTD
PMID:19000753
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
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Col1a1
collagen type I alpha 1 chain
decreases expression
ISO
Vanadium results in decreased expression of COL1A1 mRNA
CTD
PMID:19000753
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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Col4a6
collagen type IV alpha 6 chain
decreases expression
ISO
Vanadium results in decreased expression of COL4A6 mRNA
CTD
PMID:19000753
NCBI chr X:104,766,463...105,117,499
Ensembl chr X:104,766,957...105,117,500
G
Col5a1
collagen type V alpha 1 chain
decreases expression
ISO
Vanadium results in decreased expression of COL5A1 mRNA
CTD
PMID:19000753
NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588
G
Csk
C-terminal Src kinase
decreases expression
ISO
Vanadium results in decreased expression of CSK mRNA
CTD
PMID:19000753
NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292
G
Csnk1a1
casein kinase 1, alpha 1
decreases expression
ISO
Vanadium results in decreased expression of CSNK1A1 mRNA
CTD
PMID:19000753
NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271
G
Csnk2a2
casein kinase 2 alpha 2
decreases expression
ISO
Vanadium results in decreased expression of CSNK2A2 mRNA
CTD
PMID:19000753
NCBI chr19:9,556,443...9,596,080
Ensembl chr19:9,556,260...9,596,080
G
Cux1
cut-like homeobox 1
increases activity
ISO
Vanadium results in increased activity of CUX1 protein
CTD
PMID:19000753
NCBI chr12:20,107,062...20,425,868
Ensembl chr12:20,107,311...20,425,866
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Cxcl2
C-X-C motif chemokine ligand 2
increases expression
EXP
Vanadium results in increased expression of CXCL2 mRNA
CTD
PMID:11708899
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
multiple interactions decreases expression
ISO
Vanadium inhibits the reaction [[AHR protein binds to ARNT protein] which binds to CYP1A1 promoter]; Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A1 protein]; Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] Vanadium results in decreased expression of CYP1A1 mRNA Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A1 protein]; Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Vanadium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A1 protein]; Vanadium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
CTD
PMID:18541696 PMID:20221682 PMID:23423713
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
G
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
multiple interactions
ISO
Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein]; Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Vanadium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein]; Vanadium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]
CTD
PMID:23423713
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
G
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
multiple interactions
ISO
Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1B1 protein]; Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]; Vanadium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1B1 protein]; Vanadium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
CTD
PMID:23423713
NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
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Dgkb
diacylglycerol kinase, beta
increases expression
ISO
Vanadium results in increased expression of DGKB mRNA
CTD
PMID:19000753
NCBI chr 6:54,640,948...55,397,210
Ensembl chr 6:54,641,614...55,397,043
G
Dgkg
diacylglycerol kinase, gamma
decreases expression
ISO
Vanadium results in decreased expression of DGKG mRNA
CTD
PMID:19000753
NCBI chr11:78,384,212...78,579,158
Ensembl chr11:78,384,458...78,577,212
G
Dgki
diacylglycerol kinase, iota
increases expression
ISO
Vanadium results in increased expression of DGKI mRNA
CTD
PMID:19000753
NCBI chr 4:65,410,878...65,872,733
Ensembl chr 4:65,420,108...65,872,733
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Dgkq
diacylglycerol kinase, theta
decreases expression
ISO
Vanadium results in decreased expression of DGKQ mRNA
CTD
PMID:19000753
NCBI chr14:1,059,125...1,073,131
Ensembl chr14:1,059,170...1,073,131
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Etv4
ETS variant transcription factor 4
increases activity
ISO
Vanadium results in increased activity of ETV4 protein
CTD
PMID:19000753
NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974
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Fgf17
fibroblast growth factor 17
decreases expression
ISO
Vanadium results in decreased expression of FGF17 mRNA
CTD
PMID:19000753
NCBI chr15:45,711,498...45,717,622
Ensembl chr15:45,711,998...45,717,063
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Fgfbp1
fibroblast growth factor binding protein 1
decreases expression
ISO
Vanadium results in decreased expression of FGFBP1 mRNA
CTD
PMID:19000753
NCBI chr14:67,103,686...67,107,492
Ensembl chr14:67,104,545...67,107,496
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Fshb
follicle stimulating hormone subunit beta
decreases expression
EXP
Vanadium results in decreased expression of FSHB protein
CTD
PMID:20521886
NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
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Gja1
gap junction protein, alpha 1
increases expression
EXP
Vanadium results in increased expression of GJA1 mRNA
CTD
PMID:15159208
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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Gp1bb
glycoprotein Ib platelet subunit beta
decreases expression
ISO
Vanadium results in decreased expression of GP1BB mRNA
CTD
PMID:19000753
NCBI chr11:82,378,216...82,379,393
Ensembl chr11:82,378,199...82,379,392
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Hgf
hepatocyte growth factor
decreases expression
ISO
Vanadium results in decreased expression of HGF mRNA
CTD
PMID:19000753
NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
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Hif1a
hypoxia inducible factor 1 subunit alpha
multiple interactions
ISO
Vanadium results in increased expression of and results in increased activity of HIF1A protein
CTD
PMID:16386771
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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Hspa1a
heat shock protein family A (Hsp70) member 1A
increases expression
EXP
Vanadium results in increased expression of HSPA1A mRNA
CTD
PMID:15159208
NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
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Icam1
intercellular adhesion molecule 1
multiple interactions
ISO
[Particulate Matter results in increased abundance of Vanadium] which results in increased expression of ICAM1 protein
CTD
PMID:26732377
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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Icam4
intercellular adhesion molecule 4, Landsteiner-Wiener blood group
decreases expression
ISO
Vanadium results in decreased expression of ICAM4 mRNA
CTD
PMID:19000753
NCBI chr 8:19,566,075...19,567,171
Ensembl chr 8:19,566,075...19,567,171
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Ifng
interferon gamma
multiple interactions
ISO
[Air Pollutants results in increased abundance of Vanadium] which results in decreased methylation of IFNG promoter
CTD
PMID:28424066
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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Igfbp4
insulin-like growth factor binding protein 4
decreases expression
ISO
Vanadium results in decreased expression of IGFBP4 mRNA
CTD
PMID:19000753
NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
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Igfbp5
insulin-like growth factor binding protein 5
increases expression
ISO
Vanadium results in increased expression of IGFBP5 mRNA
CTD
PMID:19000753
NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
G
Il10
interleukin 10
multiple interactions
EXP
[Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] inhibits the reaction [Streptozocin results in decreased expression of IL10 protein]
CTD
PMID:15862027
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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Il1a
interleukin 1 alpha
increases expression
EXP
Vanadium results in increased expression of IL1A mRNA
CTD
PMID:15159208
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
G
Il4
interleukin 4
multiple interactions
EXP ISO
[Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] results in increased expression of IL4 protein [Air Pollutants results in increased abundance of Vanadium] which results in decreased methylation of IL4 promoter
CTD
PMID:15862027 PMID:28424066
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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Il6
interleukin 6
increases expression
ISO EXP
Vanadium results in increased expression of IL6 mRNA; Vanadium results in increased expression of IL6 protein
CTD
PMID:9344885 PMID:15159208
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Ins1
insulin 1
multiple interactions
ISO
[Selenium co-treated with Vitamin E co-treated with Vanadium co-treated with Chromium] results in increased expression of INS1 mRNA; [Selenium co-treated with Vitamin E co-treated with Vanadium co-treated with Chromium] results in increased expression of INS1 protein
CTD
PMID:20108212
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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Insig1
insulin induced gene 1
decreases expression
ISO
Vanadium results in decreased expression of INSIG1 mRNA
CTD
PMID:19000753
NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
G
Insl5
insulin like 5
increases expression
ISO
Vanadium results in increased expression of INSL5 mRNA
CTD
PMID:19000753
NCBI chr 5:117,773,104...117,777,376
G
Irf1
interferon regulatory factor 1
increases activity
ISO
Vanadium results in increased activity of IRF1 protein
CTD
PMID:19000753
NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
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Itga10
integrin subunit alpha 10
decreases expression
ISO
Vanadium results in decreased expression of ITGA10 mRNA
CTD
PMID:19000753
NCBI chr 2:184,182,869...184,202,172
Ensembl chr 2:184,182,869...184,202,172
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Itga3
integrin subunit alpha 3
decreases expression
ISO
Vanadium results in decreased expression of ITGA3 mRNA
CTD
PMID:19000753
NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118
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Itgax
integrin subunit alpha X
decreases expression
ISO
Vanadium results in decreased expression of ITGAX mRNA
CTD
PMID:19000753
NCBI chr 1:182,709,653...182,740,709
Ensembl chr 1:182,719,609...182,740,698
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Itgb7
integrin subunit beta 7
increases expression
ISO
Vanadium results in increased expression of ITGB7 mRNA
CTD
PMID:19000753
NCBI chr 7:133,347,927...133,364,955
Ensembl chr 7:133,347,960...133,364,876
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Jak3
Janus kinase 3
decreases expression
ISO
Vanadium results in decreased expression of JAK3 mRNA
CTD
PMID:19000753
NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536
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Kcna3
potassium voltage-gated channel subfamily A member 3
decreases expression
ISO
Vanadium results in decreased expression of KCNA3 mRNA
CTD
PMID:19000753
NCBI chr 2:194,632,106...194,634,059
Ensembl chr 2:194,632,196...194,650,138
G
Kcnc1
potassium voltage-gated channel subfamily C member 1
decreases expression
ISO
Vanadium results in decreased expression of KCNC1 mRNA
CTD
PMID:19000753
NCBI chr 1:96,902,953...96,944,744
Ensembl chr 1:96,902,953...96,944,744
G
Kcnq1
potassium voltage-gated channel subfamily Q member 1
increases expression
EXP
Vanadium results in increased expression of KCNQ1 mRNA
CTD
PMID:15159208
NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
G
Kcnq3
potassium voltage-gated channel subfamily Q member 3
increases expression
ISO
Vanadium results in increased expression of KCNQ3 mRNA
CTD
PMID:19000753
NCBI chr 7:97,730,219...98,025,652
Ensembl chr 7:97,730,465...98,025,653
G
Kcnq4
potassium voltage-gated channel subfamily Q member 4
decreases expression
ISO
Vanadium results in decreased expression of KCNQ4 mRNA
CTD
PMID:19000753
NCBI chr 5:134,275,145...134,326,992
Ensembl chr 5:134,275,934...134,326,932
G
Klf11
KLF transcription factor 11
decreases expression
ISO
Vanadium results in decreased expression of KLF11 mRNA
CTD
PMID:19000753
NCBI chr 6:41,285,699...41,297,548
Ensembl chr 6:41,285,842...41,297,550
G
Lep
leptin
multiple interactions
EXP
Vanadium promotes the reaction [LEP protein results in increased expression of UCP1 protein]; Vanadium promotes the reaction [LEP protein results in increased phosphorylation of STAT3 protein]
CTD
PMID:16195403
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
G
Lhb
luteinizing hormone subunit beta
decreases expression multiple interactions
EXP
Vanadium results in decreased expression of LHB protein Vanadium inhibits the reaction [Vanadium results in decreased expression of LHB protein]
CTD
PMID:20521886
NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
G
Litaf
lipopolysaccharide-induced TNF factor
multiple interactions
ISO
[Titanium co-treated with Vanadium co-treated with Aluminum] results in increased expression of LITAF mRNA
CTD
PMID:17408380
NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763
G
Map2k6
mitogen-activated protein kinase kinase 6
increases expression
ISO
Vanadium results in increased expression of MAP2K6 mRNA
CTD
PMID:19000753
NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
G
Map3k14
mitogen-activated protein kinase kinase kinase 14
decreases expression
ISO
Vanadium results in decreased expression of MAP3K14 mRNA
CTD
PMID:19000753
NCBI chr10:88,165,349...88,215,558
Ensembl chr10:88,165,351...88,215,523
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Map3k2
mitogen activated protein kinase kinase kinase 2
increases expression
ISO
Vanadium results in increased expression of MAP3K2 mRNA
CTD
PMID:19000753
NCBI chr18:23,807,218...23,879,722
Ensembl chr18:23,807,218...23,871,433
G
Map3k4
mitogen activated protein kinase kinase kinase 4
decreases expression
ISO
Vanadium results in decreased expression of MAP3K4 mRNA
CTD
PMID:19000753
NCBI chr 1:48,431,801...48,519,358
Ensembl chr 1:48,431,830...48,519,358
G
Map4k4
mitogen-activated protein kinase kinase kinase kinase 4
decreases expression
ISO
Vanadium results in decreased expression of MAP4K4 mRNA
CTD
PMID:19000753
NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698
G
Mapk1
mitogen activated protein kinase 1
multiple interactions increases phosphorylation
EXP ISO
[Vanadium co-treated with Iron] results in increased phosphorylation of MAPK1 protein; Vanadium results in increased phosphorylation of and results in increased activity of MAPK1 protein Vanadium results in increased phosphorylation of MAPK1 protein
CTD
PMID:14622970 PMID:16079071 PMID:16728372
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
G
Mapk3
mitogen activated protein kinase 3
multiple interactions increases phosphorylation
EXP ISO
[Vanadium co-treated with Iron] results in increased phosphorylation of MAPK3 protein; Vanadium results in increased phosphorylation of and results in increased activity of MAPK3 protein Vanadium results in increased phosphorylation of MAPK3 protein
CTD
PMID:14622970 PMID:16079071 PMID:16728372
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
G
Mapkapk3
MAPK activated protein kinase 3
increases expression
ISO
Vanadium results in increased expression of MAPKAPK3 mRNA
CTD
PMID:19000753
NCBI chr 8:107,929,754...107,963,638
Ensembl chr 8:107,929,762...107,963,568
G
Megf8
multiple EGF-like-domains 8
increases expression
ISO
Vanadium results in increased expression of MEGF8 mRNA
CTD
PMID:19000753
NCBI chr 1:80,902,236...80,951,614
Ensembl chr 1:80,902,574...80,951,613
G
Mfap2
microfibril associated protein 2
increases expression
ISO
Vanadium results in increased expression of MFAP2 mRNA
CTD
PMID:19000753
NCBI chr 5:153,312,068...153,320,266
Ensembl chr 5:153,314,711...153,320,259
G
Mki67
marker of proliferation Ki-67
multiple interactions
EXP
Vanadium inhibits the reaction [2-Acetylaminofluorene results in increased expression of MKI67 protein]
CTD
PMID:15565650
NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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Mmp1
matrix metallopeptidase 1
decreases expression
ISO
Vanadium results in decreased expression of MMP1 mRNA
CTD
PMID:19000753
NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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Mmp14
matrix metallopeptidase 14
increases expression
ISO
Vanadium results in increased expression of MMP14 mRNA
CTD
PMID:19000753
NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
G
Mst1r
macrophage stimulating 1 receptor
decreases expression
ISO
Vanadium results in decreased expression of MST1R mRNA
CTD
PMID:19000753
NCBI chr 8:108,596,100...108,611,441
Ensembl chr 8:108,597,299...108,612,455
G
Mt1
metallothionein 1
multiple interactions
EXP
Vanadium inhibits the reaction [2-Acetylaminofluorene results in increased expression of MT1A protein]
CTD
PMID:15565650
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049
G
Muc5ac
mucin 5AC, oligomeric mucus/gel-forming
increases expression
ISO
Vanadium results in increased expression of MUC5AC mRNA
CTD
PMID:10637131
NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475
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Myo18a
myosin XVIIIa
decreases expression
ISO
Vanadium results in decreased expression of MYO18A mRNA
CTD
PMID:19000753
NCBI chr10:62,654,218...62,755,465
Ensembl chr10:62,654,281...62,755,468
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Ndrg1
N-myc downstream regulated 1
increases expression
ISO
Vanadium results in increased expression of NDRG1 protein
CTD
PMID:16386771
NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
G
Nedd9
neural precursor cell expressed, developmentally down-regulated 9
increases activity
ISO
Vanadium results in increased activity of NEDD9 protein
CTD
PMID:19000753
NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019
G
Nos2
nitric oxide synthase 2
multiple interactions
EXP ISO
Vanadium inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of NOS2 mRNA] [Air Pollutants results in increased abundance of Vanadium] which results in decreased methylation of NOS2 promoter
CTD
PMID:18155637 PMID:28424066
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Nos3
nitric oxide synthase 3
increases expression
ISO
Vanadium results in increased expression of NOS3 mRNA
CTD
PMID:19000753
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
G
Npy
neuropeptide Y
increases expression
ISO
Vanadium results in increased expression of NPY mRNA
CTD
PMID:19000753
NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
G
Nqo1
NAD(P)H quinone dehydrogenase 1
multiple interactions increases stability decreases expression
ISO
Vanadium inhibits the reaction [sulforaphane affects the localization of NQO1 protein]; Vanadium inhibits the reaction [sulforaphane results in increased activity of NQO1 protein]; Vanadium inhibits the reaction [sulforaphane results in increased expression of NQO1 mRNA]; Vanadium inhibits the reaction [sulforaphane results in increased expression of NQO1 protein]; Vanadium inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of NQO1 protein]; Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]; Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 protein] Vanadium results in increased stability of NQO1 protein Vanadium results in decreased expression of NQO1 mRNA
CTD
PMID:19367690
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Nrcam
neuronal cell adhesion molecule
decreases expression
ISO
Vanadium results in decreased expression of NRCAM mRNA
CTD
PMID:19000753
NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992
G
P4hb
prolyl 4-hydroxylase subunit beta
decreases expression
ISO
Vanadium results in decreased expression of P4HB mRNA
CTD
PMID:19000753
NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
G
Pcna
proliferating cell nuclear antigen
multiple interactions
EXP
Vanadium inhibits the reaction [2-Acetylaminofluorene results in increased expression of PCNA protein]; Vanadium inhibits the reaction [Diethylnitrosamine results in increased expression of PCNA protein]
CTD
PMID:16352317 PMID:16878318
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
G
Pecam1
platelet and endothelial cell adhesion molecule 1
decreases expression
ISO
Vanadium results in decreased expression of PECAM1 mRNA
CTD
PMID:19000753
NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
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Pfkp
phosphofructokinase, platelet
decreases expression
ISO
Vanadium results in decreased expression of PFKP mRNA
CTD
PMID:19000753
NCBI chr17:63,729,743...63,794,026
Ensembl chr17:63,729,780...63,794,018
G
Pick1
protein interacting with PRKCA 1
decreases expression
ISO
Vanadium results in decreased expression of PICK1 mRNA
CTD
PMID:19000753
NCBI chr 7:110,796,623...110,816,850
Ensembl chr 7:110,797,117...110,816,848
G
Pik3r3
phosphoinositide-3-kinase regulatory subunit 3
increases expression
ISO
Vanadium results in increased expression of PIK3R3 mRNA
CTD
PMID:19000753
NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583
G
Pkn1
protein kinase N1
decreases expression
ISO
Vanadium results in decreased expression of PKN1 mRNA
CTD
PMID:19000753
NCBI chr19:24,442,130...24,470,107
Ensembl chr19:24,442,122...24,470,107
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Pla2g2a
phospholipase A2 group IIA
increases expression
ISO
Vanadium results in increased expression of PLA2G2A mRNA
CTD
PMID:19000753
NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
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Plau
plasminogen activator, urokinase
increases expression
ISO
Vanadium results in increased expression of PLAU mRNA
CTD
PMID:19000753
NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
G
Prkaca
protein kinase cAMP-activated catalytic subunit alpha
decreases expression
ISO
Vanadium results in decreased expression of PRKACA mRNA
CTD
PMID:19000753
NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
G
Prkca
protein kinase C, alpha
multiple interactions
ISO
PRKCA protein affects the reaction [Vanadium results in increased phosphorylation of and results in increased activity of AKT1 protein]; PRKCA protein affects the reaction [Vanadium results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]
CTD
PMID:14971662
NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
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Prkcb
protein kinase C, beta
decreases expression
ISO
Vanadium results in decreased expression of PRKCB mRNA
CTD
PMID:19000753
NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
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Prkcd
protein kinase C, delta
increases expression
ISO
Vanadium results in increased expression of PRKCD mRNA
CTD
PMID:19000753
NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
G
Prkci
protein kinase C, iota
affects localization increases expression multiple interactions
ISO
Vanadium affects the localization of PRKCI protein Vanadium results in increased expression of PRKCI mRNA PRKCI protein mutant form inhibits the reaction [Vanadium results in increased phosphorylation of and results in increased activity of AKT1 protein]
CTD
PMID:14971662 PMID:19000753
NCBI chr 2:112,321,919...112,382,305
Ensembl chr 2:112,321,929...112,382,352
G
Prkcq
protein kinase C, theta
decreases expression
ISO
Vanadium results in decreased expression of PRKCQ mRNA
CTD
PMID:19000753
NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704
G
Prkcz
protein kinase C, zeta
affects localization
ISO
Vanadium affects the localization of PRKCZ protein
CTD
PMID:14971662
NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
G
Prkd1
protein kinase D1
decreases expression
ISO
Vanadium results in decreased expression of PRKD1 mRNA
CTD
PMID:19000753
NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042
G
Prkg1
protein kinase cGMP-dependent 1
decreases expression
ISO
Vanadium results in decreased expression of PRKG1 mRNA
CTD
PMID:19000753
NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080
G
Prkg2
protein kinase cGMP-dependent 2
decreases expression
ISO
Vanadium results in decreased expression of PRKG2 mRNA
CTD
PMID:19000753
NCBI chr14:10,559,882...10,668,479
Ensembl chr14:10,559,882...10,666,888
G
Ptgs1
prostaglandin-endoperoxide synthase 1
multiple interactions
ISO
[Vanadates results in increased abundance of Vanadium] which results in decreased expression of PTGS1 protein
CTD
PMID:25398544
NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
G
Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
ISO
[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide co-treated with [Vanadates results in increased abundance of Vanadium]] results in increased expression of PTGS2 protein
CTD
PMID:25398544
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
G
Ptk2b
protein tyrosine kinase 2 beta
decreases expression
ISO
Vanadium results in decreased expression of PTK2B mRNA
CTD
PMID:19000753
NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
G
Ptk6
protein tyrosine kinase 6
decreases expression
ISO
Vanadium results in decreased expression of PTK6 mRNA
CTD
PMID:19000753
NCBI chr 3:168,307,073...168,315,664
Ensembl chr 3:168,307,073...168,315,664
G
Rps6kb1
ribosomal protein S6 kinase B1
multiple interactions
ISO
PRKCA protein affects the reaction [Vanadium results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]; Vanadium results in increased phosphorylation of and results in increased activity of RPS6KB1 protein
CTD
PMID:14971662
NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
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S1pr4
sphingosine-1-phosphate receptor 4
increases expression
ISO
Vanadium results in increased expression of S1PR4 mRNA
CTD
PMID:19000753
NCBI chr 7:8,207,767...8,210,043
Ensembl chr 7:8,208,098...8,211,893
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Scn10a
sodium voltage-gated channel alpha subunit 10
increases expression
ISO
Vanadium results in increased expression of SCN10A mRNA
CTD
PMID:19000753
NCBI chr 8:119,350,723...119,462,882
Ensembl chr 8:119,350,724...119,462,614
G
Slc11a2
solute carrier family 11 member 2
decreases expression multiple interactions
EXP
Vanadium results in decreased expression of SLC11A2 mRNA; Vanadium results in decreased expression of SLC11A2 protein Metals inhibits the reaction [SLC11A2 protein results in increased transport of Vanadium]
CTD
PMID:15908475
NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
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Slc12a2
solute carrier family 12 member 2
increases expression
ISO
Vanadium results in increased expression of SLC12A2 mRNA
CTD
PMID:19000753
NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440
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Slc12a7
solute carrier family 12 member 7
decreases expression
ISO
Vanadium results in decreased expression of SLC12A7 mRNA
CTD
PMID:19000753
NCBI chr 1:29,472,692...29,554,246
Ensembl chr 1:29,472,692...29,554,302
G
Slc13a2
solute carrier family 13 member 2
decreases expression
ISO
Vanadium results in decreased expression of SLC13A2 mRNA
CTD
PMID:19000753
NCBI chr10:63,291,813...63,319,127
Ensembl chr10:63,291,815...63,319,127
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Slc14a2
solute carrier family 14 member 2
increases expression
ISO
Vanadium results in increased expression of SLC14A2 mRNA
CTD
PMID:19000753
NCBI chr18:71,612,460...72,039,462
Ensembl chr18:71,612,460...71,792,968
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Slc15a1
solute carrier family 15 member 1
decreases expression
ISO
Vanadium results in decreased expression of SLC15A1 mRNA
CTD
PMID:19000753
NCBI chr15:98,537,641...98,582,544
Ensembl chr15:98,537,641...98,582,545
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Slc16a5
solute carrier family 16 member 5
increases expression
ISO
Vanadium results in increased expression of SLC16A5 mRNA
CTD
PMID:19000753
NCBI chr10:100,707,434...100,721,338
Ensembl chr10:100,707,434...100,721,338
G
Slc17a5
solute carrier family 17 member 5
increases expression
ISO
Vanadium results in increased expression of SLC17A5 mRNA
CTD
PMID:19000753
NCBI chr 8:79,394,416...79,429,387
G
Slc18a3
solute carrier family 18 member A3
multiple interactions decreases expression
EXP
Nicotine inhibits the reaction [Vanadium results in decreased expression of SLC18A3 protein]
CTD
PMID:22119111
NCBI chr16:7,713,630...7,716,491
G
Slc1a1
solute carrier family 1 member 1
decreases expression
ISO
Vanadium results in decreased expression of SLC1A1 mRNA
CTD
PMID:19000753
NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402
G
Slc1a4
solute carrier family 1 member 4
decreases expression
ISO
Vanadium results in decreased expression of SLC1A4 mRNA
CTD
PMID:19000753
NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418
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Slc22a14
solute carrier family 22, member 14
increases expression
ISO
Vanadium results in increased expression of SLC22A14 mRNA
CTD
PMID:19000753
NCBI chr 8:118,894,537...118,916,416
Ensembl chr 8:118,895,259...118,908,255
G
Slc23a1
solute carrier family 23 member 1
increases expression
ISO
Vanadium results in increased expression of SLC23A1 mRNA
CTD
PMID:19000753
NCBI chr18:27,214,940...27,230,564
Ensembl chr18:27,216,281...27,230,697
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Slc2a4
solute carrier family 2 member 4
decreases expression
ISO
Vanadium results in decreased expression of SLC2A4 mRNA
CTD
PMID:19000753
NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
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Slc30a3
solute carrier family 30 member 3
decreases expression
ISO
Vanadium results in decreased expression of SLC30A3 mRNA
CTD
PMID:19000753
NCBI chr 6:25,264,310...25,284,720
Ensembl chr 6:25,275,528...25,284,720
G
Slc30a4
solute carrier family 30 member 4
decreases expression
ISO
Vanadium results in decreased expression of SLC30A4 mRNA
CTD
PMID:19000753
NCBI chr 3:109,753,270...109,775,306
Ensembl chr 3:109,753,273...109,775,306
G
Slc31a1
solute carrier family 31 member 1
decreases expression
ISO
Vanadium results in decreased expression of SLC31A1 mRNA
CTD
PMID:19000753
NCBI chr 5:75,814,744...75,844,241
Ensembl chr 5:75,814,743...75,844,228
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Slc39a1
solute carrier family 39 member 1
decreases expression
ISO
Vanadium results in decreased expression of SLC39A1 mRNA
CTD
PMID:19000753
NCBI chr 2:175,703,413...175,709,063
Ensembl chr 2:175,703,441...175,709,058
G
Slc6a9
solute carrier family 6 member 9
decreases expression
ISO
Vanadium results in decreased expression of SLC6A9 mRNA
CTD
PMID:19000753
NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728
G
Slco2b1
solute carrier organic anion transporter family, member 2b1
increases expression
ISO
Vanadium results in increased expression of SLCO2B1 mRNA
CTD
PMID:19000753
NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353
G
Slco4a1
solute carrier organic anion transporter family, member 4a1
decreases expression
ISO
Vanadium results in decreased expression of SLCO4A1 mRNA
CTD
PMID:19000753
NCBI chr 3:167,559,177...167,578,307
Ensembl chr 3:167,559,316...167,578,305
G
Smarcd1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
decreases expression
ISO
Vanadium results in decreased expression of SMARCD1 mRNA
CTD
PMID:19000753
NCBI chr 7:130,829,783...130,840,323
Ensembl chr 7:130,829,768...130,840,323
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Stat3
signal transducer and activator of transcription 3
multiple interactions
EXP
Vanadium promotes the reaction [LEP protein results in increased phosphorylation of STAT3 protein]
CTD
PMID:16195403
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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Stk38
serine/threonine kinase 38
increases expression
ISO
Vanadium results in increased expression of STK38 mRNA
CTD
PMID:19000753
NCBI chr20:7,034,245...7,067,803
Ensembl chr20:7,034,242...7,068,198
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Tap2
transporter 2, ATP binding cassette subfamily B member
increases expression
ISO
Vanadium results in increased expression of TAP2 mRNA
CTD
PMID:19000753
NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407
G
Tbxas1
thromboxane A synthase 1
decreases expression
ISO
Vanadium results in decreased expression of TBXAS1 mRNA
CTD
PMID:19000753
NCBI chr 4:67,664,963...67,837,096
Ensembl chr 4:67,665,007...67,837,096
G
Timp1
TIMP metallopeptidase inhibitor 1
decreases expression
ISO
Vanadium results in decreased expression of TIMP1 mRNA
CTD
PMID:19000753
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
G
Tnf
tumor necrosis factor
multiple interactions
ISO EXP
[Titanium co-treated with Vanadium co-treated with Aluminum] results in increased expression of TNF mRNA [Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] inhibits the reaction [Streptozocin results in increased expression of TNF protein]
CTD
PMID:15862027 PMID:17408380
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
G
Tp53
tumor protein p53
multiple interactions increases activity
EXP ISO
Vanadium inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of TP53 protein]; Vanadium promotes the reaction [2-Acetylaminofluorene results in increased expression of TP53 protein] Vanadium results in increased activity of TP53 protein
CTD
PMID:15565650 PMID:18155637 PMID:19000753
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Troap
trophinin associated protein
increases expression
ISO
Vanadium results in increased expression of TROAP mRNA
CTD
PMID:19000753
NCBI chr 7:130,233,534...130,242,369
Ensembl chr 7:130,234,544...130,242,365
G
Ucp1
uncoupling protein 1
multiple interactions
EXP
Vanadium promotes the reaction [LEP protein results in increased expression of UCP1 protein]
CTD
PMID:16195403
NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852
G
Usf1
upstream transcription factor 1
increases activity
ISO
Vanadium results in increased activity of USF1 protein
CTD
PMID:19000753
NCBI chr13:83,845,230...83,854,875
Ensembl chr13:83,822,035...83,854,885
G
Vcam1
vascular cell adhesion molecule 1
multiple interactions
ISO
[Particulate Matter results in increased abundance of Vanadium] which results in increased expression of VCAM1 protein
CTD
PMID:26732377
NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
G
Vdac2
voltage-dependent anion channel 2
increases expression
ISO
Vanadium results in increased expression of VDAC2 mRNA
CTD
PMID:19000753
NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553
G
Vegfd
vascular endothelial growth factor D
increases expression
ISO
Vanadium results in increased expression of VEGFD mRNA
CTD
PMID:19000753
NCBI chr X:30,073,122...30,108,413
Ensembl chr X:30,074,163...30,108,295
G
Zap70
zeta chain of T cell receptor associated protein kinase 70
decreases expression
ISO
Vanadium results in decreased expression of ZAP70 mRNA
CTD
PMID:19000753
NCBI chr 9:38,989,750...39,011,701
Ensembl chr 9:38,989,750...39,011,700
G
Acp3
acid phosphatase 3
decreases expression
ISO
vanadyl sulfate results in decreased expression of ACP3 mRNA
CTD
PMID:16330358
NCBI chr 8:104,905,570...104,956,146
Ensembl chr 8:104,905,586...104,954,236
G
Adipoq
adiponectin, C1Q and collagen domain containing
multiple interactions
ISO
NL-71-101 inhibits the reaction [vanadyl sulfate results in increased expression of ADIPOQ protein]; vanadyl sulfate results in increased expression of and results in increased secretion of ADIPOQ protein
CTD
PMID:16524741
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
G
Alas1
5'-aminolevulinate synthase 1
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in decreased expression of ALAS1 mRNA]
CTD
PMID:16684804
NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917
G
Alb
albumin
increases expression
ISO
vanadyl sulfate results in increased expression of ALB mRNA
CTD
PMID:16330358
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
G
Angptl1
angiopoietin-like 1
increases expression
ISO
vanadyl sulfate results in increased expression of ANGPTL1 mRNA
CTD
PMID:16330358
NCBI chr13:68,963,186...68,981,649
Ensembl chr13:68,962,991...68,992,570
G
Ankrd1
ankyrin repeat domain 1
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of ANKRD1 mRNA]
CTD
PMID:16684804
NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
G
Apoe
apolipoprotein E
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of APOE mRNA]
CTD
PMID:16684804
NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
G
Aqp7
aquaporin 7
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of AQP7 mRNA]
CTD
PMID:16684804
NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642
G
Arnt
aryl hydrocarbon receptor nuclear translocator
decreases expression
ISO
vanadyl sulfate results in decreased expression of ARNT mRNA
CTD
PMID:16330358
NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
G
Arrdc3
arrestin domain containing 3
decreases expression
ISO
vanadyl sulfate results in decreased expression of ARRDC3 mRNA
CTD
PMID:16330358
NCBI chr 2:11,137,464...11,149,978
Ensembl chr 2:11,137,460...11,149,978
G
Arrdc4
arrestin domain containing 4
decreases expression
ISO
vanadyl sulfate results in decreased expression of ARRDC4 mRNA
CTD
PMID:16330358
NCBI chr 1:122,369,355...122,383,351
Ensembl chr 1:122,369,360...122,383,290
G
Atf2
activating transcription factor 2
increases phosphorylation
ISO
vanadyl sulfate results in increased phosphorylation of ATF2 protein
CTD
PMID:9728050
NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
G
Bax
BCL2 associated X, apoptosis regulator
decreases expression
ISO
vanadyl sulfate results in decreased expression of BAX protein
CTD
PMID:30407648
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
G
Bcl2
BCL2, apoptosis regulator
decreases expression
ISO
vanadyl sulfate results in decreased expression of BCL2 protein
CTD
PMID:30407648
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
G
Bcl6
BCL6, transcription repressor
decreases expression
ISO
vanadyl sulfate results in decreased expression of BCL6 mRNA
CTD
PMID:16330358
NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
G
Bcor
BCL6 co-repressor
decreases expression
ISO
vanadyl sulfate results in decreased expression of BCOR mRNA
CTD
PMID:16330358
NCBI chr X:10,609,756...10,729,613
Ensembl chr X:10,687,732...10,729,613
G
C1qb
complement C1q B chain
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of C1QB mRNA]
CTD
PMID:16684804
NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407
G
C4b
complement C4B
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of C4B mRNA]
CTD
PMID:16684804
NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681
G
Cacng2
calcium voltage-gated channel auxiliary subunit gamma 2
increases expression
ISO
vanadyl sulfate results in increased expression of CACNG2 mRNA
CTD
PMID:16330358
NCBI chr 7:109,572,838...109,698,516
Ensembl chr 7:109,574,459...109,697,227
G
Calm1
calmodulin 1
decreases expression
ISO
vanadyl sulfate results in decreased expression of CALM1 mRNA
CTD
PMID:16330358
NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
G
Casp1
caspase 1
decreases expression
ISO
vanadyl sulfate results in decreased expression of CASP1 protein
CTD
PMID:30407648
NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
G
Casp3
caspase 3
decreases cleavage
ISO
vanadyl sulfate results in decreased cleavage of CASP3 protein
CTD
PMID:30407648
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp9
caspase 9
decreases expression
ISO
vanadyl sulfate results in decreased expression of CASP9 protein
CTD
PMID:30407648
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
G
Cat
catalase
multiple interactions
ISO
CAT protein inhibits the reaction [vanadyl sulfate results in increased activity of RELA protein]; CAT protein inhibits the reaction [vanadyl sulfate results in increased degradation of NFKBIA protein]
CTD
PMID:10873158
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
G
Ccdc85b
coiled-coil domain containing 85B
increases expression
ISO
vanadyl sulfate results in increased expression of CCDC85B mRNA
CTD
PMID:16330358
NCBI chr 1:202,763,645...202,764,660
Ensembl chr 1:202,763,631...202,764,703
G
Ccl2
C-C motif chemokine ligand 2
increases expression multiple interactions
ISO EXP
vanadyl sulfate results in increased expression of CCL2 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]
CTD
PMID:16330358 PMID:16684804
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
G
Ccl5
C-C motif chemokine ligand 5
increases expression
ISO
vanadyl sulfate results in increased expression of CCL5 protein
CTD
PMID:18684396
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
G
Ccnf
cyclin F
decreases expression
ISO
vanadyl sulfate results in decreased expression of CCNF mRNA
CTD
PMID:16330358
NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101
G
Cinp
cyclin-dependent kinase 2-interacting protein
decreases expression
ISO
vanadyl sulfate results in decreased expression of CINP mRNA
CTD
PMID:16330358
NCBI chr 6:129,878,618...129,899,575
Ensembl chr 6:129,885,570...129,899,480
G
Cirbp
cold inducible RNA binding protein
decreases expression
ISO
vanadyl sulfate results in decreased expression of CIRBP mRNA
CTD
PMID:16330358
NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818
G
Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CITED2 mRNA]
CTD
PMID:16684804
NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
G
Ckmt2
creatine kinase, mitochondrial 2
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in decreased expression of CKMT2 mRNA]
CTD
PMID:16684804
NCBI chr 2:23,079,918...23,110,518
Ensembl chr 2:23,079,918...23,110,430
G
Cldn1
claudin 1
increases expression
ISO
vanadyl sulfate results in increased expression of CLDN1 mRNA
CTD
PMID:16330358
NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
G
Cldn4
claudin 4
increases expression
ISO
vanadyl sulfate results in increased expression of CLDN4 mRNA
CTD
PMID:16330358
NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
G
Cpt1a
carnitine palmitoyltransferase 1A
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CPT1A mRNA]
CTD
PMID:16684804
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
G
Cpvl
carboxypeptidase, vitellogenic-like
increases expression
ISO
vanadyl sulfate results in increased expression of CPVL mRNA
CTD
PMID:16330358
NCBI chr 4:82,981,421...83,091,730
Ensembl chr 4:82,981,422...83,085,655
G
Crh
corticotropin releasing hormone
decreases expression
ISO
vanadyl sulfate results in decreased expression of CRH mRNA
CTD
PMID:16330358
NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
G
Csf2
colony stimulating factor 2
increases expression
ISO
vanadyl sulfate results in increased expression of CSF2 protein
CTD
PMID:18684396
NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
G
Csnk1d
casein kinase 1, delta
increases expression
ISO
vanadyl sulfate results in increased expression of CSNK1D mRNA
CTD
PMID:16330358
NCBI chr10:106,221,992...106,256,620
Ensembl chr10:106,221,992...106,256,614
G
Csrp3
cysteine and glycine rich protein 3
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CSRP3 mRNA]
CTD
PMID:16684804
NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653
G
Ctsg
cathepsin G
increases expression
ISO
vanadyl sulfate results in increased expression of CTSG mRNA
CTD
PMID:16330358
NCBI chr15:29,930,988...29,937,353
Ensembl chr15:29,931,003...29,937,353
G
Ctss
cathepsin S
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CTSS mRNA]
CTD
PMID:16684804
NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483
G
Cxcl1
C-X-C motif chemokine ligand 1
increases expression
ISO
vanadyl sulfate results in increased expression of CXCL1 mRNA
CTD
PMID:16330358
NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
G
Cxcl2
C-X-C motif chemokine ligand 2
increases expression
ISO
vanadyl sulfate results in increased expression of CXCL2 protein
CTD
PMID:18684396
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
G
Cxcl3
C-X-C motif chemokine ligand 3
increases expression
ISO
vanadyl sulfate results in increased expression of CXCL1 mRNA
CTD
PMID:16330358
NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
G
Cybb
cytochrome b-245 beta chain
decreases expression
ISO
vanadyl sulfate results in decreased expression of CYBB mRNA
CTD
PMID:16330358
NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586
G
Cyp11a1
cytochrome P450, family 11, subfamily a, polypeptide 1
increases expression
ISO
vanadyl sulfate results in increased expression of CYP11A1 mRNA
CTD
PMID:16330358
NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
G
Ddx39b
DExD-box helicase 39B
decreases expression
ISO
vanadyl sulfate results in decreased expression of DDX39B mRNA
CTD
PMID:16330358
NCBI chr20:3,547,702...3,585,064
Ensembl chr20:3,572,056...3,584,996
G
Decr1
2,4-dienoyl-CoA reductase 1
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of DECR1 mRNA]
CTD
PMID:16684804
NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
G
Denr
density regulated reinitiation and release factor
decreases expression
ISO
vanadyl sulfate results in decreased expression of DENR mRNA
CTD
PMID:16330358
NCBI chr12:32,662,512...32,685,283
Ensembl chr12:32,662,516...32,683,843
G
Drp2
dystrophin related protein 2
increases expression
ISO
vanadyl sulfate results in increased expression of DRP2 mRNA
CTD
PMID:16330358
NCBI chr X:97,607,577...97,658,117
Ensembl chr X:97,607,719...97,655,684
G
Dusp1
dual specificity phosphatase 1
increases expression
ISO
vanadyl sulfate results in increased expression of DUSP1 mRNA
CTD
PMID:16330358
NCBI chr10:16,680,478...16,683,275
G
Dusp21
dual specificity phosphatase 21
increases expression
ISO
vanadyl sulfate results in increased expression of DUSP21 mRNA
CTD
PMID:16330358
NCBI chr X:4,488,021...4,488,877
Ensembl chr X:4,488,021...4,488,877
G
Dusp5
dual specificity phosphatase 5
increases expression
ISO
vanadyl sulfate results in increased expression of DUSP5 mRNA
CTD
PMID:16330358
NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
G
Edn1
endothelin 1
increases expression
ISO
vanadyl sulfate results in increased expression of EDN1 mRNA
CTD
PMID:16330358
NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
G
Egfr
epidermal growth factor receptor
increases phosphorylation
ISO
vanadyl sulfate results in increased phosphorylation of EGFR protein
CTD
PMID:10564177 PMID:11943669
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
G
Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of EIF4EBP1 mRNA]
CTD
PMID:16684804
NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
G
Elk1
ETS transcription factor ELK1
increases activity multiple interactions
ISO
vanadyl sulfate results in increased activity of ELK1 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [vanadyl sulfate results in increased activity of ELK1 protein]
CTD
PMID:10564177
NCBI chr X:1,138,826...1,155,713
Ensembl chr X:1,139,756...1,155,713
G
Errfi1
ERBB receptor feedback inhibitor 1
increases expression
ISO
vanadyl sulfate results in increased expression of ERRFI1 mRNA
CTD
PMID:16330358
NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
G
Faslg
Fas ligand
decreases expression
ISO
vanadyl sulfate results in decreased expression of FASLG protein
CTD
PMID:30407648
NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
G
Fbxo5
F-box protein 5
decreases expression
ISO
vanadyl sulfate results in decreased expression of FBXO5 mRNA
CTD
PMID:16330358
NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
G
Fcgr2a
Fc gamma receptor 2A
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of FCGR3 mRNA]
CTD
PMID:16684804
NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
G
Fgd6
FYVE, RhoGEF and PH domain containing 6
increases expression
ISO
vanadyl sulfate results in increased expression of FGD6 mRNA
CTD
PMID:16330358
NCBI chr 7:28,597,609...28,712,908
Ensembl chr 7:28,597,609...28,712,456
G
Fgfr2
fibroblast growth factor receptor 2
increases expression
ISO
vanadyl sulfate results in increased expression of FGFR2 mRNA
CTD
PMID:16330358
NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
vanadyl sulfate results in increased expression of FOS mRNA
CTD
PMID:16330358
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
G
Fyb1
FYN binding protein 1
decreases expression
ISO
vanadyl sulfate results in decreased expression of FYB1 mRNA
CTD
PMID:16330358
NCBI chr 2:55,621,585...55,781,206
Ensembl chr 2:55,632,698...55,779,629
G
Galt
galactose-1-phosphate uridylyltransferase
decreases expression
ISO
vanadyl sulfate results in decreased expression of GALT mRNA
CTD
PMID:16330358
NCBI chr 5:56,927,039...56,930,284
Ensembl chr 5:56,926,724...56,930,265
G
Gcnt2
glucosaminyl (N-acetyl) transferase 2
increases expression
ISO
vanadyl sulfate results in increased expression of GCNT2 mRNA
CTD
PMID:16330358
NCBI chr17:23,796,859...23,901,625
Ensembl chr17:23,796,859...23,901,611
G
Gpr137b
G protein-coupled receptor 137B
decreases expression
ISO
vanadyl sulfate results in decreased expression of GPR137B mRNA
CTD
PMID:16330358
NCBI chr17:86,003,635...86,041,841
Ensembl chr17:85,966,921...86,041,835
G
Gsta3
glutathione S-transferase alpha 3
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of GSTA3 mRNA]
CTD
PMID:16684804
NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
G
Gstm2
glutathione S-transferase mu 2
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of GSTM2 mRNA]
CTD
PMID:16684804
NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
G
Gstm5l
glutathione S-transferase, mu 5-like
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of GSTM5 mRNA]
CTD
PMID:16684804
NCBI chr 2:195,544,424...195,549,895
Ensembl chr 2:195,544,426...195,628,961
G
Hal
histidine ammonia lyase
increases expression
ISO
vanadyl sulfate results in increased expression of HAL mRNA
CTD
PMID:16330358
NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
G
Hbegf
heparin-binding EGF-like growth factor
increases expression
ISO
vanadyl sulfate results in increased expression of HBEGF mRNA
CTD
PMID:18684396
NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
G
Hmgcs2
3-hydroxy-3-methylglutaryl-CoA synthase 2
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of HMGCS2 mRNA]
CTD
PMID:16684804
NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
G
Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
decreases expression
ISO
vanadyl sulfate results in decreased expression of HNRNPA2B1 mRNA
CTD
PMID:16330358
NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249
G
Hoxd9
homeo box D9
increases expression
ISO
vanadyl sulfate results in increased expression of HOXD9 mRNA
CTD
PMID:16330358
NCBI chr 3:59,600,575...59,602,755
Ensembl chr 3:59,600,575...59,602,754
G
Hs3st1
heparan sulfate-glucosamine 3-sulfotransferase 1
increases expression
ISO
vanadyl sulfate results in increased expression of HS3ST1 mRNA
CTD
PMID:16330358
NCBI chr14:71,185,826...71,223,263
Ensembl chr14:71,185,682...71,223,248
G
Ica1
islet cell autoantigen 1
decreases expression
ISO
vanadyl sulfate results in decreased expression of ICA1 mRNA
CTD
PMID:16330358
NCBI chr 4:36,656,475...36,804,705
Ensembl chr 4:36,656,475...36,804,298
G
Icam2
intercellular adhesion molecule 2
increases expression
ISO
vanadyl sulfate results in increased expression of ICAM2 mRNA
CTD
PMID:16330358
NCBI chr10:91,308,608...91,319,536
Ensembl chr10:91,308,538...91,315,293
G
Id3
inhibitor of DNA binding 3
decreases expression
ISO
vanadyl sulfate results in decreased expression of ID3 mRNA
CTD
PMID:16330358
NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
G
Ifne
interferon, epsilon
increases expression
ISO
vanadyl sulfate results in increased expression of IFNE mRNA
CTD
PMID:16330358
NCBI chr 5:103,571,630...103,572,290
Ensembl chr 5:103,569,675...103,572,256
G
Il1a
interleukin 1 alpha
increases expression
ISO
vanadyl sulfate results in increased expression of IL1A mRNA
CTD
PMID:16330358
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
G
Il1b
interleukin 1 beta
multiple interactions
ISO
vanadyl sulfate affects the reaction [Lipopolysaccharides results in increased expression of IL1B protein]
CTD
PMID:16217019
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Il1r1
interleukin 1 receptor type 1
increases expression
ISO
vanadyl sulfate results in increased expression of IL1R1 mRNA
CTD
PMID:16217019
NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
G
Il1r2
interleukin 1 receptor type 2
increases expression
ISO
vanadyl sulfate results in increased expression of IL1R2 mRNA
CTD
PMID:16217019
NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
G
Il36g
interleukin 36, gamma
increases expression
ISO
vanadyl sulfate results in increased expression of IL36G mRNA
CTD
PMID:16330358
NCBI chr 3:6,948,323...6,954,485
Ensembl chr 3:6,948,297...6,954,480
G
Il6
interleukin 6
increases expression multiple interactions
ISO
vanadyl sulfate results in increased expression of IL6 protein vanadyl sulfate affects the reaction [Lipopolysaccharides results in increased expression of IL6 protein]
CTD
PMID:16217019 PMID:18684396
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Impa2
inositol monophosphatase 2
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of IMPA2 mRNA]
CTD
PMID:16684804
NCBI chr18:60,834,206...60,867,575
Ensembl chr18:60,834,246...60,865,641
G
Itpr3
inositol 1,4,5-trisphosphate receptor, type 3
increases expression
ISO
vanadyl sulfate results in increased expression of ITPR3 mRNA
CTD
PMID:16330358
NCBI chr20:5,136,968...5,202,339
Ensembl chr20:5,136,441...5,202,337
G
Jam2
junctional adhesion molecule 2
increases expression
ISO
vanadyl sulfate results in increased expression of JAM2 mRNA
CTD
PMID:16330358
NCBI chr11:23,830,820...23,880,071
Ensembl chr11:23,831,106...23,880,063
G
Jun
Jun proto-oncogene, AP-1 transcription factor subunit
increases phosphorylation
ISO
vanadyl sulfate results in increased phosphorylation of JUN protein
CTD
PMID:9728050
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
G
Kbtbd6
kelch repeat and BTB domain containing 6
decreases expression
ISO
vanadyl sulfate results in decreased expression of KBTBD6 mRNA
CTD
PMID:16330358
NCBI chr15:54,848,285...54,850,042
Ensembl chr15:54,848,446...54,850,453
G
Kctd6
potassium channel tetramerization domain containing 6
decreases expression
ISO
vanadyl sulfate results in decreased expression of KCTD6 mRNA
CTD
PMID:16330358
NCBI chr15:16,695,297...16,712,460
Ensembl chr15:16,695,297...16,698,699
G
Kdm4d
lysine demethylase 4D
increases expression
ISO
vanadyl sulfate results in increased expression of KDM4D mRNA
CTD
PMID:16330358
NCBI chr 8:11,279,756...11,304,920
Ensembl chr 8:11,268,859...11,305,290
G
Klhl41
kelch-like family member 41
increases expression
ISO
vanadyl sulfate results in increased expression of KLHL41 mRNA
CTD
PMID:16330358
NCBI chr 3:54,434,291...54,447,415
Ensembl chr 3:54,434,234...54,449,222
G
Krt36
keratin 36
increases expression
ISO
vanadyl sulfate results in increased expression of KRT36 mRNA
CTD
PMID:16330358
NCBI chr10:85,036,379...85,040,003
Ensembl chr10:85,036,594...85,039,959
G
Krt86
keratin 86
increases expression
ISO
vanadyl sulfate results in increased expression of KRT86 mRNA
CTD
PMID:16330358
NCBI chr 7:132,591,489...132,598,142
Ensembl chr 7:132,591,545...132,598,021
G
Lgals3
galectin 3
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of LGALS3 mRNA]
CTD
PMID:16684804
NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
G
Lhx9
LIM homeobox 9
decreases expression
ISO
vanadyl sulfate results in decreased expression of LHX9 mRNA
CTD
PMID:16330358
NCBI chr13:50,389,052...50,409,947
Ensembl chr13:50,389,738...50,410,806
G
Lif
LIF, interleukin 6 family cytokine
increases expression
ISO
vanadyl sulfate results in increased expression of LIF mRNA
CTD
PMID:16330358
NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
G
Lins1
lines homolog 1
decreases expression
ISO
vanadyl sulfate results in decreased expression of LINS1 mRNA
CTD
PMID:16330358
NCBI chr 1:120,267,586...120,295,013
Ensembl chr 1:120,267,693...120,293,607
G
Lipe
lipase E, hormone sensitive type
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of LIPE mRNA]
CTD
PMID:16684804
NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
G
Lyz2
lysozyme 2
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of LYZ mRNA]
CTD
PMID:16684804
NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106
G
Map2k1
mitogen activated protein kinase kinase 1
multiple interactions increases phosphorylation
ISO
4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [vanadyl sulfate results in increased phosphorylation of MAP2K1 protein]; MRAS mutant form inhibits the reaction [vanadyl sulfate results in increased phosphorylation of MAP2K1 protein]; vanadyl sulfate results in increased phosphorylation of and results in increased activity of MAP2K1 protein
CTD
PMID:10564177 PMID:11943669
NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
G
Map2k2
mitogen activated protein kinase kinase 2
multiple interactions increases phosphorylation
ISO
4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [vanadyl sulfate results in increased phosphorylation of MAP2K2 protein]; MRAS mutant form inhibits the reaction [vanadyl sulfate results in increased phosphorylation of MAP2K2 protein]; vanadyl sulfate results in increased phosphorylation of and results in increased activity of MAP2K2 protein
CTD
PMID:10564177 PMID:11943669
NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
G
Mapk1
mitogen activated protein kinase 1
multiple interactions increases phosphorylation
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [vanadyl sulfate results in increased phosphorylation of MAPK1 protein]; MRAS mutant form inhibits the reaction [vanadyl sulfate results in increased phosphorylation of MAPK1 protein]; vanadyl sulfate results in increased phosphorylation of and results in increased activity of MAPK1 protein
CTD
PMID:9728050 PMID:10564177 PMID:11943669
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
G
Mapk14
mitogen activated protein kinase 14
decreases expression
ISO
vanadyl sulfate results in decreased expression of MAPK14 mRNA
CTD
PMID:16330358
NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
G
Mapk3
mitogen activated protein kinase 3
multiple interactions increases phosphorylation
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [vanadyl sulfate results in increased phosphorylation of MAPK3 protein]; MRAS mutant form inhibits the reaction [vanadyl sulfate results in increased phosphorylation of MAPK3 protein]; vanadyl sulfate results in increased phosphorylation of and results in increased activity of MAPK3 protein
CTD
PMID:10564177 PMID:11943669
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
G
Mchr1
melanin-concentrating hormone receptor 1
increases expression
ISO
vanadyl sulfate results in increased expression of MCHR1 mRNA
CTD
PMID:16330358
NCBI chr 7:112,761,554...112,764,746
Ensembl chr 7:112,761,554...112,764,032
G
Mmp1
matrix metallopeptidase 1
increases expression
ISO
vanadyl sulfate results in increased expression of MMP1 mRNA; vanadyl sulfate results in increased expression of MMP1 protein
CTD
PMID:18684396
NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
G
Mmp25
matrix metallopeptidase 25
increases expression
ISO
vanadyl sulfate results in increased expression of MMP25 mRNA
CTD
PMID:16330358
NCBI chr10:12,661,297...12,676,119
Ensembl chr10:12,661,208...12,675,871
G
Mras
muscle RAS oncogene homolog
multiple interactions increases activity
ISO
4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [vanadyl sulfate results in increased activity of MRAS protein]; MRAS mutant form inhibits the reaction [vanadyl sulfate results in increased activity of and affects the localization of [RELA protein binds to NFKB1 protein]]; MRAS mutant form inhibits the reaction [vanadyl sulfate results in increased degradation of NFKBIA protein]; MRAS mutant form inhibits the reaction [vanadyl sulfate results in increased phosphorylation of MAP2K1 protein]; MRAS mutant form inhibits the reaction [vanadyl sulfate results in increased phosphorylation of MAP2K2 protein]; MRAS mutant form inhibits the reaction [vanadyl sulfate results in increased phosphorylation of MAPK1 protein]; MRAS mutant form inhibits the reaction [vanadyl sulfate results in increased phosphorylation of MAPK3 protein]
CTD
PMID:11943669
NCBI chr 8:99,944,036...100,006,771
Ensembl chr 8:99,944,036...99,996,408
G
Mt1
metallothionein 1
multiple interactions increases expression
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of MT1A mRNA] vanadyl sulfate results in increased expression of MT1A mRNA
CTD
PMID:16684804 PMID:19679144
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049
G
Myh3
myosin heavy chain 3
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of MYH3 mRNA]
CTD
PMID:16684804
NCBI chr10:51,770,177...51,793,994
Ensembl chr10:51,770,177...51,793,992
G
Myo3b
myosin IIIB
decreases expression
ISO
vanadyl sulfate results in decreased expression of MYO3B mRNA
CTD
PMID:16330358
NCBI chr 3:54,820,225...55,228,518
Ensembl chr 3:54,820,251...55,227,373
G
Nfkb1
nuclear factor kappa B subunit 1
multiple interactions
ISO
MRAS mutant form inhibits the reaction [vanadyl sulfate results in increased activity of and affects the localization of [RELA protein binds to NFKB1 protein]]; vanadyl sulfate results in increased activity of and affects the localization of [RELA protein binds to NFKB1 protein]
CTD
PMID:11943669
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
G
Nfkbia
NFKB inhibitor alpha
multiple interactions increases degradation increases phosphorylation
ISO EXP
4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [vanadyl sulfate results in increased degradation of NFKBIA protein]; CAT protein inhibits the reaction [vanadyl sulfate results in increased degradation of NFKBIA protein]; MRAS mutant form inhibits the reaction [vanadyl sulfate results in increased degradation of NFKBIA protein]; NFKBIA protein mutant form inhibits the reaction [vanadyl sulfate affects the localization of RELA protein]; NFKBIA protein mutant form inhibits the reaction [vanadyl sulfate results in increased expression of CXCL8 mRNA] vanadyl sulfate results in increased phosphorylation of NFKBIA protein vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of NFKBIA mRNA]
CTD
PMID:10521501 PMID:10873158 PMID:11943669 PMID:16684804
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
G
Nfkbib
NFKB inhibitor beta
increases degradation
ISO
vanadyl sulfate results in increased degradation of NFKBIB protein
CTD
PMID:10521501
NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
G
Npy
neuropeptide Y
increases expression
EXP
vanadyl sulfate results in increased expression of NPY mRNA
CTD
PMID:11294500
NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
G
P2ry2
purinergic receptor P2Y2
decreases expression
ISO
vanadyl sulfate results in decreased expression of P2RY2 mRNA
CTD
PMID:16330358
NCBI chr 1:155,352,050...155,367,423
Ensembl chr 1:155,351,165...155,367,632
G
Pak6
p21 (RAC1) activated kinase 6
decreases expression
ISO
vanadyl sulfate results in decreased expression of PAK6 mRNA
CTD
PMID:16330358
NCBI chr 3:105,638,248...105,674,399
Ensembl chr 3:105,638,653...105,672,975
G
Pdcd6
programmed cell death 6
increases expression
ISO
vanadyl sulfate results in increased expression of PDCD6 mRNA
CTD
PMID:16330358
NCBI chr 1:28,966,518...28,982,188
Ensembl chr 1:28,966,518...28,982,189
G
Pde4dip
phosphodiesterase 4D interacting protein
increases expression
ISO
vanadyl sulfate results in increased expression of PDE4DIP mRNA
CTD
PMID:16330358
NCBI chr 2:185,293,236...185,490,100
Ensembl chr 2:185,293,214...185,468,379
G
Pdk2
pyruvate dehydrogenase kinase 2
increases expression
ISO
vanadyl sulfate results in increased expression of PDK2 mRNA
CTD
PMID:16330358
NCBI chr10:79,972,550...79,987,074
Ensembl chr10:79,972,556...79,987,085
G
Pdlim3
PDZ and LIM domain 3
increases expression
ISO
vanadyl sulfate results in increased expression of PDLIM3 mRNA
CTD
PMID:16330358
NCBI chr16:46,352,460...46,383,680
Ensembl chr16:46,352,467...46,383,657
G
Pdxp
pyridoxal phosphatase
decreases expression
ISO
vanadyl sulfate results in decreased expression of PDXP mRNA
CTD
PMID:16330358
NCBI chr 7:110,472,515...110,477,963
Ensembl chr 7:110,472,515...110,477,963
G
Pla2g12b
phospholipase A2, group XIIB
increases expression
ISO
vanadyl sulfate results in increased expression of PLA2G12B mRNA
CTD
PMID:16330358
NCBI chr20:27,369,196...27,389,517
Ensembl chr20:27,370,266...27,388,743
G
Pla2g1b
phospholipase A2 group IB
increases expression
ISO
vanadyl sulfate results in increased expression of PLA2G1B mRNA
CTD
PMID:16330358
NCBI chr12:41,142,193...41,151,967
Ensembl chr12:41,142,200...41,153,226
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Plaur
plasminogen activator, urokinase receptor
increases expression
ISO
vanadyl sulfate results in increased expression of PLAUR mRNA
CTD
PMID:16330358
NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595
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Plekhb1
pleckstrin homology domain containing B1
increases expression
ISO
vanadyl sulfate results in increased expression of PLEKHB1 mRNA
CTD
PMID:16330358
NCBI chr 1:154,998,798...155,013,094
Ensembl chr 1:154,998,800...155,016,142
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Pml
PML nuclear body scaffold
decreases expression
ISO
vanadyl sulfate results in decreased expression of PML mRNA
CTD
PMID:16330358
NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
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Polr3g
RNA polymerase III subunit G
increases expression
ISO
vanadyl sulfate results in increased expression of POLR3G mRNA
CTD
PMID:16330358
NCBI chr 2:11,945,215...11,986,125
Ensembl chr 2:11,945,217...11,986,125
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Ppef2
protein phosphatase with EF-hand domain 2
increases expression
ISO
vanadyl sulfate results in increased expression of PPEF2 mRNA
CTD
PMID:16330358
NCBI chr14:15,797,414...15,831,620
Ensembl chr14:15,797,435...15,831,491
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Ppp1r10
protein phosphatase 1, regulatory subunit 10
increases expression
ISO
vanadyl sulfate results in increased expression of PPP1R10 mRNA
CTD
PMID:16330358
NCBI chr20:2,822,995...2,838,125
Ensembl chr20:2,822,995...2,837,611
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Prdm1
PR/SET domain 1
increases expression
ISO
vanadyl sulfate results in increased expression of PRDM1 mRNA
CTD
PMID:16330358
NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488
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Ptgs2
prostaglandin-endoperoxide synthase 2
increases expression
ISO
vanadyl sulfate results in increased expression of PTGS2 mRNA
CTD
PMID:16330358
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Pth
parathyroid hormone
decreases expression
ISO
vanadyl sulfate results in decreased expression of PTH mRNA
CTD
PMID:16330358
NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530
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Ptpn1
protein tyrosine phosphatase, non-receptor type 1
decreases activity
ISO
vanadyl sulfate results in decreased activity of PTPN1 protein
CTD
PMID:10460753
NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504
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Ptpre
protein tyrosine phosphatase, receptor type, E
increases expression
ISO
vanadyl sulfate results in increased expression of PTPRE mRNA
CTD
PMID:16330358
NCBI chr 1:190,344,331...190,494,815
Ensembl chr 1:190,344,401...190,489,534
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Rara
retinoic acid receptor, alpha
decreases expression
ISO
vanadyl sulfate results in decreased expression of RARA mRNA
CTD
PMID:16330358
NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
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Rars2
arginyl-tRNA synthetase 2, mitochondrial
increases expression
ISO
vanadyl sulfate results in increased expression of RARS2 mRNA
CTD
PMID:16330358
NCBI chr 5:49,181,517...49,238,664
Ensembl chr 5:49,181,565...49,233,276
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Rce1
Ras converting CAAX endopeptidase 1
increases expression
ISO
vanadyl sulfate results in increased expression of RCE1 mRNA
CTD
PMID:16330358
NCBI chr 1:201,899,358...201,902,593
Ensembl chr 1:201,899,358...201,902,484
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Rchy1
ring finger and CHY zinc finger domain containing 1
decreases expression
ISO
vanadyl sulfate results in decreased expression of RCHY1 mRNA
CTD
PMID:16330358
NCBI chr14:16,113,263...16,129,017
Ensembl chr14:16,113,224...16,129,167
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Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
ISO
CAT protein inhibits the reaction [vanadyl sulfate results in increased activity of RELA protein]; MRAS mutant form inhibits the reaction [vanadyl sulfate results in increased activity of and affects the localization of [RELA protein binds to NFKB1 protein]]; NFKBIA protein mutant form inhibits the reaction [vanadyl sulfate affects the localization of RELA protein]; SB 203580 inhibits the reaction [vanadyl sulfate results in increased activity of RELA protein]; vanadyl sulfate affects the localization of and results in increased activity of RELA protein; vanadyl sulfate results in increased activity of and affects the localization of [RELA protein binds to NFKB1 protein]; vanadyl sulfate results in increased localization of and results in increased activity of RELA protein
CTD
PMID:10521501 PMID:10873158 PMID:11943669
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Rgs2
regulator of G-protein signaling 2
increases expression
ISO
vanadyl sulfate results in increased expression of RGS2 mRNA
CTD
PMID:16330358
NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
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Rhoj
ras homolog family member J
increases expression
ISO
vanadyl sulfate results in increased expression of RHOJ mRNA
CTD
PMID:16330358
NCBI chr 6:94,035,307...94,117,642
Ensembl chr 6:94,035,483...94,118,275
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Rims3
regulating synaptic membrane exocytosis 3
decreases expression
ISO
vanadyl sulfate results in decreased expression of RIMS3 mRNA
CTD
PMID:16330358
NCBI chr 5:134,429,092...134,468,935
Ensembl chr 5:134,435,829...134,640,489
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Rpl13
ribosomal protein L13
increases expression
ISO
vanadyl sulfate results in increased expression of RPL13 mRNA
CTD
PMID:16330358
NCBI chr19:51,153,990...51,156,541
Ensembl chr19:51,153,924...51,163,014
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Rpl18a
ribosomal protein L18A
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of RPL18A mRNA]
CTD
PMID:16684804
NCBI chr16:18,542,555...18,544,578
Ensembl chr16:18,542,566...18,545,546
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Rps3
ribosomal protein S3
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of RPS3 mRNA]
CTD
PMID:16684804
NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680
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Rrad
RRAD, Ras related glycolysis inhibitor and calcium channel regulator
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of RRAD mRNA]
CTD
PMID:16684804
NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417
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S100a6
S100 calcium binding protein A6
decreases expression
ISO
vanadyl sulfate results in decreased expression of S100A6 mRNA
CTD
PMID:16330358
NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180
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S1pr3
sphingosine-1-phosphate receptor 3
increases expression
ISO
vanadyl sulfate results in increased expression of S1PR3 mRNA
CTD
PMID:16330358
NCBI chr17:13,781,050...13,794,408
Ensembl chr17:13,781,050...13,794,505
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Scarf2
scavenger receptor class F, member 2
decreases expression
ISO
vanadyl sulfate results in decreased expression of SCARF2 mRNA
CTD
PMID:16330358
NCBI chr11:83,175,956...83,187,415
Ensembl chr11:83,175,963...83,187,348
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Sdccag8
SHH signaling and ciliogenesis regulator SDCCAG8
decreases expression
ISO
vanadyl sulfate results in decreased expression of SDCCAG8 mRNA
CTD
PMID:16330358
NCBI chr13:88,754,521...88,979,363
Ensembl chr13:88,754,626...89,097,111
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Serpinb2
serpin family B member 2
increases expression
ISO
vanadyl sulfate results in increased expression of SERPINB2 mRNA
CTD
PMID:16330358
NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408
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Serpini2
serpin family I member 2
increases expression
ISO
vanadyl sulfate results in increased expression of SERPINI2 mRNA
CTD
PMID:16330358
NCBI chr 2:160,014,721...160,044,271
Ensembl chr 2:160,014,721...160,044,280
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Siglec8
sialic acid binding Ig-like lectin 8
increases expression
ISO
vanadyl sulfate results in increased expression of SIGLEC8 mRNA
CTD
PMID:16330358
NCBI chr 1:94,092,737...94,103,134
Ensembl chr 1:94,093,395...94,103,034
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Sipa1l3
signal-induced proliferation-associated 1 like 3
increases expression
ISO
vanadyl sulfate results in increased expression of SIPA1L3 mRNA
CTD
PMID:16330358
NCBI chr 1:84,618,714...84,825,956
Ensembl chr 1:84,618,719...84,703,802
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Six1
SIX homeobox 1
decreases expression
ISO
vanadyl sulfate results in decreased expression of SIX1 mRNA
CTD
PMID:16330358
NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975
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Six2
SIX homeobox 2
decreases expression
ISO
vanadyl sulfate results in decreased expression of SIX2 mRNA
CTD
PMID:16330358
NCBI chr 6:8,974,859...8,981,345
Ensembl chr 6:8,967,157...8,981,193
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Slc13a3
solute carrier family 13 member 3
increases expression
ISO
vanadyl sulfate results in increased expression of SLC13A3 mRNA
CTD
PMID:16330358
NCBI chr 3:154,141,878...154,204,604
Ensembl chr 3:154,141,872...154,204,606
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Slc22a16
solute carrier family 22 member 16
increases expression
ISO
vanadyl sulfate results in increased expression of SLC22A16 mRNA
CTD
PMID:16330358
NCBI chr20:43,972,808...44,068,447
Ensembl chr20:43,972,836...44,065,019
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Slc26a3
solute carrier family 26 member 3
decreases expression
ISO
vanadyl sulfate results in decreased expression of SLC26A3 mRNA
CTD
PMID:16330358
NCBI chr 6:48,023,892...48,064,829
Ensembl chr 6:48,023,892...48,064,772
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Slc27a1
solute carrier family 27 member 1
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of SLC27A1 mRNA]
CTD
PMID:16684804
NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
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Smad4
SMAD family member 4
decreases expression
ISO
vanadyl sulfate results in decreased expression of SMAD4 mRNA
CTD
PMID:16330358
NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
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Sncg
synuclein, gamma
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of SNCG mRNA]
CTD
PMID:16684804
NCBI chr16:9,700,513...9,705,751
Ensembl chr16:9,700,514...9,705,368
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Sox2
SRY-box transcription factor 2
decreases expression
ISO
vanadyl sulfate results in decreased expression of SOX2 mRNA
CTD
PMID:16330358
NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338
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Spp1
secreted phosphoprotein 1
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of SPP1 mRNA]
CTD
PMID:16684804
NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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St3gal5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of ST3GAL5 mRNA]
CTD
PMID:16684804
NCBI chr 4:104,134,613...104,192,558
Ensembl chr 4:104,134,613...104,192,558
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Stat3
signal transducer and activator of transcription 3
increases expression
ISO
vanadyl sulfate results in increased expression of STAT3 mRNA
CTD
PMID:16330358
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
G
Stau2
staufen double-stranded RNA binding protein 2
decreases expression
ISO
vanadyl sulfate results in decreased expression of STAU2 mRNA
CTD
PMID:16330358
NCBI chr 5:2,840,741...3,084,935
Ensembl chr 5:2,840,765...3,084,929
G
Ston1
stonin 1
increases expression
ISO
vanadyl sulfate results in increased expression of STON1 mRNA
CTD
PMID:16330358
NCBI chr 6:5,843,186...5,892,557
Ensembl chr 6:5,843,185...5,892,449
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Stx6
syntaxin 6
increases expression
ISO
vanadyl sulfate results in increased expression of STX6 mRNA
CTD
PMID:16330358
NCBI chr13:67,332,329...67,378,580
Ensembl chr13:67,332,314...67,378,576
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Taf6l
TATA-box binding protein associated factor 6 like
decreases expression
ISO
vanadyl sulfate results in decreased expression of TAF6L mRNA
CTD
PMID:16330358
NCBI chr 1:205,672,147...205,684,721
Ensembl chr 1:205,672,149...205,684,655
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Tbx1
T-box transcription factor 1
decreases expression
ISO
vanadyl sulfate results in decreased expression of TBX1 mRNA
CTD
PMID:16330358
NCBI chr11:82,409,275...82,419,058
Ensembl chr11:82,409,275...82,418,380
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Terf2
telomeric repeat binding factor 2
decreases expression
ISO
vanadyl sulfate results in decreased expression of TERF2 mRNA
CTD
PMID:16330358
NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819
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Thbs4
thrombospondin 4
multiple interactions
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of THBS4 mRNA]
CTD
PMID:16684804
NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313
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Tifa
TRAF-interacting protein with forkhead-associated domain
decreases expression
ISO
vanadyl sulfate results in decreased expression of TIFA mRNA
CTD
PMID:16330358
NCBI chr 2:216,257,926...216,267,635
Ensembl chr 2:216,234,774...216,267,841
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Tnfaip3
TNF alpha induced protein 3
increases expression
ISO
vanadyl sulfate results in increased expression of TNFAIP3 mRNA
CTD
PMID:16330358
NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
G
Tor2a
torsin family 2, member A
decreases expression
ISO
vanadyl sulfate results in decreased expression of TOR2A mRNA
CTD
PMID:16330358
NCBI chr 3:16,048,591...16,053,198
Ensembl chr 3:16,048,549...16,052,634
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Tpm1
tropomyosin 1
decreases expression
ISO
vanadyl sulfate results in decreased expression of TPM1 mRNA
CTD
PMID:16330358
NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
G
Tpp2
tripeptidyl peptidase 2
decreases expression
ISO
vanadyl sulfate results in decreased expression of TPP2 mRNA
CTD
PMID:16330358
NCBI chr 9:46,046,712...46,128,157
Ensembl chr 9:46,046,632...46,128,157
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Trex1
three prime repair exonuclease 1
increases expression
ISO
vanadyl sulfate results in increased expression of TREX1 mRNA
CTD
PMID:16330358
NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796
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Wars2
tryptophanyl tRNA synthetase 2 (mitochondrial)
increases expression
ISO
vanadyl sulfate results in increased expression of WARS2 mRNA
CTD
PMID:16330358
NCBI chr 2:186,459,744...186,543,581
Ensembl chr 2:186,459,444...186,543,571
G
Xaf1
XIAP associated factor 1
decreases expression
ISO
vanadyl sulfate results in decreased expression of XAF1 mRNA
CTD
PMID:16330358
NCBI chr10:56,917,378...56,929,791
Ensembl chr10:56,917,121...56,929,770
G
Zbtb1
zinc finger and BTB domain containing 1
decreases expression
ISO
vanadyl sulfate results in decreased expression of ZBTB1 mRNA
CTD
PMID:16330358
NCBI chr 6:95,096,838...95,125,811
Ensembl chr 6:95,096,387...95,118,996
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Zbtb24
zinc finger and BTB domain containing 24
decreases expression
ISO
vanadyl sulfate results in decreased expression of ZBTB24 mRNA
CTD
PMID:16330358
NCBI chr20:44,943,302...44,965,329
Ensembl chr20:44,947,297...44,963,963
G
Zdhhc21
zinc finger DHHC-type palmitoyltransferase 21
decreases expression
ISO
vanadyl sulfate results in decreased expression of ZDHHC21 mRNA
CTD
PMID:16330358
NCBI chr 5:97,227,621...97,286,866
Ensembl chr 5:97,229,345...97,286,537
G
Zfp46
zinc finger protein 46
decreases expression
ISO
vanadyl sulfate results in decreased expression of ZNF436 mRNA
CTD
PMID:16330358
NCBI chr 5:148,519,398...148,529,903
Ensembl chr 5:148,520,855...148,529,459
G
Zfp503
zinc finger protein 503
decreases expression
ISO
vanadyl sulfate results in decreased expression of ZNF503 mRNA
CTD
PMID:16330358
NCBI chr15:2,313,060...2,316,848
Ensembl chr15:2,313,060...2,316,848
G
Zkscan3
zinc finger with KRAB and SCAN domains 3
increases expression
ISO
vanadyl sulfate results in increased expression of ZKSCAN3 mRNA
CTD
PMID:16330358
NCBI chr17:43,217,168...43,232,828
Ensembl chr17:43,217,222...43,232,827
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