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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:herbacetin
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Accession:CHEBI:27673 term browser browse the term
Definition:A pentahydroxyflavone that is kaempferol substituted by a hydroxy group at position 8. It is a natural flavonoid from flaxseed which exerts antioxidant, anti-inflammatory and anticancer activities.
Synonyms:exact_synonym: 3,5,7,8-tetrahydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
 related_synonym: 3,4',5,7,8-pentahydroxyflavone;   3,5,7,8-tetrahydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;   8-hydroxykaempferol;   Formula=C15H10O7;   InChI=1S/C15H10O7/c16-7-3-1-6(2-4-7)14-13(21)12(20)10-8(17)5-9(18)11(19)15(10)22-14/h1-5,16-19,21H;   InChIKey=ZDOTZEDNGNPOEW-UHFFFAOYSA-N;   SMILES=OC1=CC=C(C=C1)C1=C(O)C(=O)C2=C(O1)C(O)=C(O)C=C2O
 alt_id: CHEBI:20809;   CHEBI:2322
 xref: CAS:527-95-7;   KEGG:C02806;   KNApSAcK:C00001048;   LIPID_MAPS_instance:LMPK12113149
 xref_mesh: MESH:C581534
 xref: MetaCyc:CPD-14867;   PMID:23063593;   PMID:24081687;   PMID:26297979;   PMID:26676750;   PMID:26923730;   PMID:29029040;   PMID:29653099;   PMID:30899386;   PMID:31075281;   PMID:31356124;   PMID:31436895;   PMID:31724441;   PMID:32746637;   Wikipedia:Herbacetin


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herbacetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fasn fatty acid synthase multiple interactions ISO herbacetin inhibits the reaction [Dietary Fats results in increased activity of FASN protein] CTD PMID:29653099 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions ISO herbacetin inhibits the reaction [Dietary Fats results in increased activity of G6PD protein] CTD PMID:29653099 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO herbacetin inhibits the reaction [Dietary Fats results in increased activity of GPT protein] CTD PMID:29653099 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO herbacetin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:29653099 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions ISO herbacetin inhibits the reaction [Dietary Fats results in increased expression of SREBF2 mRNA] CTD PMID:29653099 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19818
    role 19790
      application 19622
        anti-inflammatory agent 16505
          herbacetin 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    p-block element atom 19761
                      carbon group element atom 19703
                        carbon atom 19698
                          organic molecular entity 19698
                            organic molecule 19656
                              organic cyclic compound 19461
                                organic heterocyclic compound 18817
                                  oxacycle 17770
                                    benzopyran 11699
                                      1-benzopyran 11461
                                        flavonoid 6821
                                          anthoxanthin 4506
                                            flavones 4506
                                              hydroxyflavone 4492
                                                flavonols 4393
                                                  7-hydroxyflavonol 4370
                                                    kaempferol 191
                                                      herbacetin 5
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