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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:herbacetin
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Accession:CHEBI:27673 term browser browse the term
Definition:A pentahydroxyflavone that is kaempferol substituted by a hydroxy group at position 8. It is a natural flavonoid from flaxseed which exerts antioxidant, anti-inflammatory and anticancer activities.
Synonyms:exact_synonym: 3,5,7,8-tetrahydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
 related_synonym: 3,4',5,7,8-pentahydroxyflavone;   3,5,7,8-tetrahydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;   8-hydroxykaempferol;   Formula=C15H10O7;   InChI=1S/C15H10O7/c16-7-3-1-6(2-4-7)14-13(21)12(20)10-8(17)5-9(18)11(19)15(10)22-14/h1-5,16-19,21H;   InChIKey=ZDOTZEDNGNPOEW-UHFFFAOYSA-N;   SMILES=OC1=CC=C(C=C1)C1=C(O)C(=O)C2=C(O1)C(O)=C(O)C=C2O
 alt_id: CHEBI:20809;   CHEBI:2322
 xref: CAS:527-95-7;   KEGG:C02806;   KNApSAcK:C00001048;   LIPID_MAPS_instance:LMPK12113149
 xref_mesh: MESH:C581534
 xref: MetaCyc:CPD-14867;   PMID:23063593;   PMID:24081687;   PMID:26297979;   PMID:26676750;   PMID:26923730;   PMID:29029040;   PMID:29653099;   PMID:30899386;   PMID:31075281;   PMID:31356124;   PMID:31436895;   PMID:31724441;   PMID:32746637;   Wikipedia:Herbacetin



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herbacetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fasn fatty acid synthase multiple interactions ISO herbacetin inhibits the reaction [Dietary Fats results in increased activity of FASN protein] CTD PMID:29653099 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions ISO herbacetin inhibits the reaction [Dietary Fats results in increased activity of G6PD protein] CTD PMID:29653099 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO herbacetin inhibits the reaction [Dietary Fats results in increased activity of GPT protein] CTD PMID:29653099 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO herbacetin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:29653099 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions ISO herbacetin inhibits the reaction [Dietary Fats results in increased expression of SREBF2 mRNA] CTD PMID:29653099 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link

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Path 1
Term Annotations click to browse term
  CHEBI ontology 19860
    role 19832
      application 19675
        anti-inflammatory agent 16628
          herbacetin 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19860
    subatomic particle 19858
      composite particle 19858
        hadron 19858
          baryon 19858
            nucleon 19858
              atomic nucleus 19858
                atom 19858
                  main group element atom 19804
                    p-block element atom 19804
                      carbon group element atom 19745
                        carbon atom 19741
                          organic molecular entity 19741
                            organic molecule 19692
                              organic cyclic compound 19503
                                organic heterocyclic compound 18875
                                  oxacycle 17892
                                    benzopyran 11975
                                      1-benzopyran 11728
                                        flavonoid 7209
                                          anthoxanthin 4547
                                            flavones 4547
                                              hydroxyflavone 4525
                                                flavonols 4413
                                                  7-hydroxyflavonol 4390
                                                    kaempferol 199
                                                      herbacetin 5
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