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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:chlortetracycline
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Accession:CHEBI:27644 term browser browse the term
Definition:A member of the class of tetracyclines with formula C22H23ClN2O8 isolated from Streptomyces aureofaciens.
Synonyms:exact_synonym: (4S,4aS,5aS,6S,12aS)-7-chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
 related_synonym: 7-Chlorotetracycline;   Aueromycin;   Formula=C22H23ClN2O8;   InChI=1S/C22H23ClN2O8/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21/h4-5,7-8,15,26,28-29,32-33H,6H2,1-3H3,(H2,24,31)/t7-,8-,15-,21-,22-/m0/s1;   InChIKey=CYDMQBQPVICBEU-XRNKAMNCSA-N;   SMILES=CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c1c(O)ccc(Cl)c1[C@@]3(C)O;   chlortetracyclinum;   clortetraciclina
 alt_id: CHEBI:23164;   CHEBI:3653
 xref: CAS:57-62-5;   Drug_Central:624;   HMDB:HMDB0014401;   KEGG:C06571;   KEGG:D07689;   LIPID_MAPS_instance:LMPK07000004
 xref_mesh: MESH:D002751
 xref: PDBeChem:CTC;   PMID:23530364;   PMID:24845506;   PMID:25131164;   PMID:25602656;   PMID:7150561;   PMID:7390959;   PMID:7988792;   Patent:US2482055
 cyclic_relationship: is_conjugate_acid_of CHEBI:133598


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chlortetracycline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase decreases activity ISO Chlortetracycline results in decreased activity of CAT protein CTD PMID:30768968 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Chlortetracycline inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
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Term Annotations click to browse term
  CHEBI ontology 19911
    role 19854
      application 19722
        probe 514
          fluorescent probe 442
            chlortetracycline 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    main group molecular entity 19849
                      s-block molecular entity 19681
                        hydrogen molecular entity 19662
                          hydrides 19167
                            organic hydride 18711
                              organic fundamental parent 18711
                                hydrocarbon 18454
                                  cyclic hydrocarbon 17239
                                    arene 17220
                                      polycyclic arene 17045
                                        ortho-fused polycyclic arene 9848
                                          acene 7798
                                            tetracene 7795
                                              tetracyclines 526
                                                chlortetracycline 2
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