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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cycloheximide
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Accession:CHEBI:27641 term browser browse the term
Definition:A dicarboximide that is 4-(2-hydroxyethyl)piperidine-2,6-dione in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 3,5-dimethyl-2-oxocyclohexyl group. It is an antibiotic produced by the bacterium Streptomyces griseus.
Synonyms:exact_synonym: 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione
 related_synonym: 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide;   Cycloheximid;   Formula=C15H23NO4;   InChI=1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1;   InChIKey=YPHMISFOHDHNIV-FSZOTQKASA-N;   SMILES=[H][C@]1(C[C@@H](C)C[C@H](C)C1=O)[C@H](O)CC1CC(=O)NC(=O)C1;   Zykloheximid;   cicloheximida;   cicloheximide;   cicloheximidum;   naramycin;   naramycin A
 alt_id: CHEBI:23484;   CHEBI:4015
 xref: Beilstein:88868;   CAS:66-81-9;   KEGG:C06685;   KEGG:D03625;   KNApSAcK:C00047211;   LINCS:LSM-2791
 xref_mesh: MESH:D003513
 xref: PDBeChem:3HE;   PMID:11972861;   PMID:16659174;   PMID:25209664;   PMID:26715760;   PMID:27192630;   PMID:27665925;   PMID:30154175;   PMID:30916348;   PMID:32299921;   PMID:33101237;   PPDB:1680;   Reaxys:88868;   Wikipedia:Cycloheximide


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cycloheximide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
multiple interactions
ISO
EXP
Cycloheximide results in increased expression of ABCB1 mRNA
Cycloheximide inhibits the reaction [[Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]; Cycloheximide inhibits the reaction [[Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]; Cycloheximide inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]; Cycloheximide inhibits the reaction [tetrabromobisphenol A results in increased expression of and results in increased activity of ABCB1A protein]; Cycloheximide inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]
Cycloheximide promotes the reaction [Reserpine results in increased expression of ABCB1 mRNA]
CTD PMID:7476894 PMID:18474546 PMID:30830211 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 multiple interactions ISO Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ABCB4 mRNA] CTD PMID:11331069 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions
increases expression
ISO [Cycloheximide co-treated with Estradiol] results in increased expression of ABCC3 mRNA
Cycloheximide results in increased expression of ABCC3 mRNA
CTD PMID:15072547 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 multiple interactions
decreases expression
ISO [Cycloheximide co-treated with Estradiol] results in decreased expression of ABCC5 mRNA
Cycloheximide results in decreased expression of ABCC5 mRNA
CTD PMID:15072547 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] affects the expression of ACSL3 mRNA CTD PMID:19684285 NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 multiple interactions EXP Cycloheximide inhibits the reaction [4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid results in increased expression of ACSL6 mRNA] CTD PMID:10585473 NCBI chr10:38,439,914...38,501,182
Ensembl chr10:38,440,080...38,498,757
JBrowse link
G Adam9 ADAM metallopeptidase domain 9 multiple interactions ISO Cycloheximide inhibits the reaction [Hydrogen Peroxide results in increased expression of ADAM9 protein] CTD PMID:17018608 NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917
JBrowse link
G Adm adrenomedullin multiple interactions
increases expression
ISO Cycloheximide promotes the reaction [Oxygen deficiency results in increased expression of ADM mRNA]
Cycloheximide results in increased expression of ADM mRNA
CTD PMID:11032871 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Adora2b adenosine A2B receptor multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ADORA2B mRNA CTD PMID:19684285 NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772
JBrowse link
G Adrb2 adrenoceptor beta 2 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of ADRB2 mRNA; Cycloheximide results in increased expression of ADRB2 protein
[Cycloheximide co-treated with EDN1 protein] results in increased expression of ADRB2 mRNA; Cycloheximide inhibits the reaction [olodaterol affects the expression of ADRB2 mRNA]; Dactinomycin inhibits the reaction [Cycloheximide results in increased expression of ADRB2 protein]; Formoterol Fumarate promotes the reaction [Cycloheximide results in increased expression of ADRB2 mRNA]; N(6)-benzoyl-cyclic AMP promotes the reaction [Cycloheximide results in increased expression of ADRB2 mRNA]
CTD PMID:22483689 PMID:24705868 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Ago3 argonaute RISC catalytic component 3 multiple interactions ISO Cycloheximide inhibits the reaction [Thapsigargin affects the localization of AGO3 mRNA] CTD PMID:29576526 NCBI chr 5:138,632,367...138,714,230
Ensembl chr 5:138,639,569...138,714,230
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases localization
decreases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of AHR protein]; Cycloheximide inhibits the reaction [TGFB1 protein results in decreased expression of AHR mRNA]; Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in increased degradation of and results in decreased expression of AHR protein]
[Cycloheximide results in increased activity of [AHR protein binds to ARNT protein]] which results in increased expression of CYP1A1 mRNA; [Tretinoin co-treated with Cycloheximide] results in increased expression of AHR mRNA; AHR protein promotes the reaction [Cycloheximide results in increased expression of TIPARP mRNA]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of AHR protein]; Cycloheximide promotes the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 enhancer]]; Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin affects the localization of AHR protein]; Cycloheximide results in increased activity of [AHR protein binds to ARNT protein]
Cycloheximide results in increased localization of AHR protein
CTD PMID:9145908 PMID:10777561 PMID:12002481 PMID:12147270 PMID:15385644 More... NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akap5 A-kinase anchoring protein 5 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of AKAP5 mRNA] CTD PMID:11007951 NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578
JBrowse link
G Akap6 A-kinase anchoring protein 6 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of AKAP6 mRNA] CTD PMID:11007951 NCBI chr 6:70,184,101...70,624,369
Ensembl chr 6:70,184,175...70,619,738
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 multiple interactions ISO Cycloheximide inhibits the reaction [cadmium acetate results in increased expression of AKR1C3 protein] CTD PMID:21787718 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation
EXP
ISO
Cycloheximide inhibits the reaction [[Hydrogen Peroxide co-treated with sodium arsenite] results in increased phosphorylation of AKT1 protein]
Cycloheximide results in increased phosphorylation of AKT1 protein
CTD PMID:12472888 PMID:28634229 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ALDH1A3 mRNA CTD PMID:19684285 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 multiple interactions EXP Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of ALDH3A1 mRNA] CTD PMID:1953764 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681
JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ALDH3A2 mRNA CTD PMID:19684285 NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ALOX5AP mRNA] CTD PMID:11007951 NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986
JBrowse link
G Alpi alkaline phosphatase, intestinal decreases activity
multiple interactions
ISO
EXP
Cycloheximide results in decreased activity of ALPI protein
Cycloheximide inhibits the reaction [Fish Oils results in increased activity of ALPI protein]
CTD PMID:15599000 PMID:20362602 NCBI chr 9:87,773,411...87,776,877
Ensembl chr 9:87,773,411...87,776,877
JBrowse link
G Amhr2 anti-Mullerian hormone receptor type 2 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of AMHR2 mRNA] CTD PMID:11007951 NCBI chr 7:133,579,152...133,588,874
Ensembl chr 7:133,579,393...133,588,258
JBrowse link
G Ank2 ankyrin 2 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ANK2 mRNA] CTD PMID:11007951 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923
JBrowse link
G Ankrd27 ankyrin repeat domain 27 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ANKRD27 mRNA CTD PMID:19684285 NCBI chr 1:88,251,216...88,303,615
Ensembl chr 1:88,251,226...88,303,615
JBrowse link
G Aoc1 amine oxidase, copper containing 1 multiple interactions EXP Cycloheximide inhibits the reaction [Epinephrine results in increased activity of AOC1 protein]; Cycloheximide inhibits the reaction [Isoproterenol results in increased activity of AOC1 protein]; Cycloheximide inhibits the reaction [Terbutaline results in increased activity of AOC1 protein] CTD PMID:2860926 PMID:6218830 NCBI chr 4:77,812,260...77,831,846
Ensembl chr 4:77,812,260...77,831,840
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of APAF1 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of APAF1 mRNA
CTD PMID:19684285 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Aqp1 aquaporin 1 multiple interactions ISO Cycloheximide inhibits the reaction [cobaltous chloride results in increased expression of AQP1 mRNA] CTD PMID:22415096 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
JBrowse link
G Aqp4 aquaporin 4 multiple interactions EXP [Lactic Acid co-treated with Cycloheximide] results in increased expression of AQP4 protein CTD PMID:18406487 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
JBrowse link
G Areg amphiregulin multiple interactions
increases expression
ISO [Cycloheximide co-treated with Estradiol] results in increased expression of AREG mRNA
Cycloheximide results in increased expression of AREG mRNA
CTD PMID:15072547 PMID:15228094 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Armc5 armadillo repeat containing 5 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ARMC5 mRNA CTD PMID:19684285 NCBI chr 1:182,820,141...182,826,913
Ensembl chr 1:182,820,141...182,826,907
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO [Cycloheximide results in increased activity of [AHR protein binds to ARNT protein]] which results in increased expression of CYP1A1 mRNA; Cycloheximide promotes the reaction [Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1A1 enhancer]]; Cycloheximide results in increased activity of [AHR protein binds to ARNT protein] CTD PMID:12002481 PMID:20570689 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
JBrowse link
G Asb1 ankyrin repeat and SOCS box-containing 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ASB1 mRNA CTD PMID:19684285 NCBI chr 9:92,120,332...92,140,790
Ensembl chr 9:92,120,306...92,136,376
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions ISO Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF3 protein] CTD PMID:23593480 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO Cycloheximide inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in increased expression of ATF4]]; Cycloheximide inhibits the reaction [Capsaicin results in increased expression of ATF4 protein]
Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF4 protein]
CTD PMID:18533110 PMID:23593480 PMID:24057571 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atg13 autophagy related 13 decreases expression ISO Cycloheximide results in decreased expression of ATG13 protein CTD PMID:27629431 NCBI chr 3:77,647,069...77,681,028
Ensembl chr 3:77,645,790...77,681,043
JBrowse link
G Atp7a ATPase copper transporting alpha multiple interactions
decreases expression
EXP cupric chloride inhibits the reaction [Cycloheximide results in decreased expression of ATP7A protein] CTD PMID:23174565 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Avpr1a arginine vasopressin receptor 1A multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of AVPR1A mRNA] CTD PMID:11007951 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215
JBrowse link
G Bach1 BTB domain and CNC homolog 1 decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of BACH1 protein
tetrachlorobenzoquinone promotes the reaction [Cycloheximide results in decreased expression of BACH1 protein]
CTD PMID:27393035 NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP Cycloheximide inhibits the reaction [TGFB1 protein results in increased expression of BAX protein] CTD PMID:9790906 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of BBOX1 mRNA] CTD PMID:11007951 NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO BCL2 protein inhibits the reaction [[Cycloheximide co-treated with TNFSF10 protein] results in increased activity of CASP3 protein]; Cycloheximide inhibits the reaction [Paclitaxel results in increased phosphorylation of BCL2 protein] CTD PMID:11726273 PMID:22343715 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of BCL2L1 protein alternative form
Dexamethasone inhibits the reaction [Cycloheximide results in increased expression of BCL2L1 protein]
CTD PMID:9326359 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l14 BCL2 like 14 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of BCL2L14 mRNA CTD PMID:19684285 NCBI chr 4:167,217,561...167,258,723
Ensembl chr 4:167,219,871...167,258,086
JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of BDH1 mRNA] CTD PMID:11007951 NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671
JBrowse link
G Becn1 beclin 1 multiple interactions ISO Cycloheximide inhibits the reaction [arsenic trioxide results in increased expression of BECN1 protein] CTD PMID:16882451 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO Cycloheximide inhibits the reaction [[Genistein co-treated with Zinc Sulfate] results in increased expression of BGLAP mRNA]; Cycloheximide inhibits the reaction [[Genistein co-treated with Zinc] results in increased expression of BGLAP mRNA] CTD PMID:17203194 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO [Cycloheximide co-treated with TNF] results in increased cleavage of BID protein; Cycloheximide inhibits the reaction [vorinostat results in increased cleavage of BID protein]; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of BID protein]; ITPK1 mutant form promotes the reaction [[Cycloheximide co-treated with TNF protein] results in increased cleavage of BID protein] CTD PMID:11535817 PMID:12925536 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bnip3 BCL2 interacting protein 3 multiple interactions ISO Cycloheximide inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein] CTD PMID:19442826 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Brca1 BRCA1, DNA repair associated multiple interactions ISO Cycloheximide inhibits the reaction [Nitrogen Mustard Compounds results in decreased expression of BRCA1 mRNA]
Cycloheximide inhibits the reaction [Thapsigargin affects the localization of BRCA1 mRNA]
CTD PMID:10344722 PMID:29576526 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brca2 BRCA2, DNA repair associated multiple interactions ISO Cycloheximide inhibits the reaction [Nitrogen Mustard Compounds results in decreased expression of BRCA2 mRNA] CTD PMID:10344722 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Calb1 calbindin 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CALB1 mRNA] CTD PMID:11007951 NCBI chr 5:29,375,624...29,402,532
Ensembl chr 5:29,375,642...29,402,431
JBrowse link
G Camlg calcium modulating ligand multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CAMLG mRNA] CTD PMID:11007951 NCBI chr17:8,992,697...9,003,576
Ensembl chr17:8,992,696...9,003,552
JBrowse link
G Casp1 caspase 1 multiple interactions ISO Cycloheximide inhibits the reaction [tetrachlorobenzoquinone results in increased expression of CASP1 protein]; Cycloheximide inhibits the reaction [tetrachlorobenzoquinone results in increased secretion of CASP1 protein modified form]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CASP1 mRNA] CTD PMID:11007951 PMID:26901245 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO
EXP
[Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP3 protein; [Cycloheximide co-treated with TNFSF10 protein] results in increased activity of CASP3 protein; BCL2 protein inhibits the reaction [[Cycloheximide co-treated with TNFSF10 protein] results in increased activity of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP3 protein]; Cycloheximide promotes the reaction [FAS protein results in increased activity of CASP3 protein]; IFI6 protein inhibits the reaction [Cycloheximide results in increased activity of CASP3 protein]; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP3 protein]
Cycloheximide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Cryptoxanthins] promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] promotes the reaction [Cryptoxanthins results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [aluminum maltolate results in increased activity of CASP3 protein]; Cycloheximide inhibits the reaction [Cryptoxanthins promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [Genistein promotes the reaction [[Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [Genistein promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [Zinc Sulfate promotes the reaction [Cryptoxanthins results in increased expression of CASP3 mRNA]]
obeticholic acid promotes the reaction [Cycloheximide results in increased activity of CASP3 protein]
CTD PMID:12760867 PMID:12925536 PMID:14502240 PMID:15537749 PMID:15685448 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CASP4 mRNA] CTD PMID:11007951 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp7 caspase 7 multiple interactions ISO Cycloheximide inhibits the reaction [Tretinoin results in increased expression of CASP7 mRNA]; Cycloheximide promotes the reaction [FAS protein results in increased activity of CASP7 protein] CTD PMID:12760867 PMID:16166294 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 multiple interactions
increases activity
ISO [Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP8 protein; [Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP8 protein; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP8 protein]; Cycloheximide promotes the reaction [FAS protein results in increased activity of CASP8 protein]; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP8 protein]
Cycloheximide results in increased activity of CASP8 protein
CTD PMID:12760867 PMID:12925536 PMID:15924153 PMID:18222423 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
ISO [Cycloheximide co-treated with TNF] results in increased activity of CASP9 protein; [Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP9 protein; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased activity of CASP9 protein]
Cycloheximide results in increased activity of CASP9 protein
CTD PMID:12925536 PMID:14502240 PMID:18222423 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions EXP Cycloheximide inhibits the reaction [Clofibrate results in increased expression of CAT protein]; Cycloheximide inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of CAT protein] CTD PMID:6845354 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Catsper4 cation channel, sperm associated 4 affects response to substance ISO CATSPER4 gene SNP affects the susceptibility to Cycloheximide CTD PMID:25622337 NCBI chr 5:146,427,682...146,447,346
Ensembl chr 5:146,427,683...146,446,942
JBrowse link
G Cav1 caveolin 1 multiple interactions ISO Cycloheximide inhibits the reaction [rosiglitazone results in increased expression of CAV1 mRNA] CTD PMID:15314095 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cbx1 chromobox 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CBX1 mRNA CTD PMID:19684285 NCBI chr10:81,770,307...81,789,981
Ensembl chr10:81,770,342...81,791,096
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
ISO Cycloheximide inhibits the reaction [TNF protein results in increased expression of CCL2 protein]; Cycloheximide inhibits the reaction [tofacitinib inhibits the reaction [TNF protein results in increased expression of CCL2 protein]]; TNF protein promotes the reaction [Cycloheximide results in increased expression of CCL2 mRNA]; Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of CCL2 mRNA]] CTD PMID:21146893 PMID:22121136 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of CCL5 mRNA
Cycloheximide inhibits the reaction [TNF protein results in increased expression of CCL5 protein]; Cycloheximide inhibits the reaction [tofacitinib inhibits the reaction [TNF protein results in increased expression of CCL5 protein]]; TNF protein promotes the reaction [Cycloheximide results in increased expression of CCL5 mRNA]; Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of CCL5 mRNA]]
CTD PMID:21146893 PMID:22121136 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions ISO Cycloheximide inhibits the reaction [Acetylcysteine results in increased expression of CCN1 protein] CTD PMID:21055460 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of CCN2 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of CCN2 mRNA
CTD PMID:19684285 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccn3 cellular communication network factor 3 multiple interactions
increases expression
ISO [Cycloheximide co-treated with Estradiol] results in decreased expression of CCN3 mRNA
Cycloheximide results in increased expression of CCN3 mRNA
CTD PMID:15072547 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019
JBrowse link
G Ccn4 cellular communication network factor 4 multiple interactions ISO Cycloheximide inhibits the reaction [2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CCN4 mRNA] CTD PMID:19238344 NCBI chr 7:98,645,238...98,677,253
Ensembl chr 7:98,645,182...98,677,248
JBrowse link
G Ccna2 cyclin A2 multiple interactions
decreases expression
ISO [Cycloheximide co-treated with Estradiol] results in increased expression of CCNA2 mRNA
Cycloheximide results in decreased expression of CCNA2 mRNA
CTD PMID:15072547 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO [gingerol co-treated with Cycloheximide] results in increased degradation of CCND1 protein; Cycloheximide inhibits the reaction [CXCL8 protein results in increased expression of CCND1 protein]; Cycloheximide inhibits the reaction [EIF4E protein modified form inhibits the reaction [sodium arsenite results in decreased expression of CCND1 protein]] CTD PMID:17606477 PMID:18058799 PMID:25923732 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd3 cyclin D3 affects expression
multiple interactions
ISO Cycloheximide affects the expression of CCND3 mRNA
Cycloheximide affects the reaction [Estradiol affects the expression of CCND3 mRNA]
CTD PMID:9094091 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of CCT5 mRNA CTD PMID:19684285 NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
JBrowse link
G Cd38 CD38 molecule multiple interactions ISO Cycloheximide affects the reaction [Tretinoin results in increased expression of CD38 mRNA] CTD PMID:21393419 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986
JBrowse link
G Cd3e CD3e molecule multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CD3E mRNA] CTD PMID:11007951 NCBI chr 8:45,303,848...45,315,297
Ensembl chr 8:45,303,852...45,315,022
JBrowse link
G Cd44 CD44 molecule (Indian blood group) multiple interactions ISO Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of CD44 protein] CTD PMID:9929743 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd47 Cd47 molecule multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CD47 mRNA] CTD PMID:11007951 NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425
JBrowse link
G Cd63 Cd63 molecule multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CD63 mRNA] CTD PMID:11007951 NCBI chr 7:1,325,108...1,340,447
Ensembl chr 7:1,325,103...1,399,178
JBrowse link
G Cd8a CD8a molecule multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CD8A mRNA CTD PMID:19684285 NCBI chr 4:103,365,804...103,370,041
Ensembl chr 4:103,365,804...103,370,040
JBrowse link
G Cdc42se2 CDC42 small effector 2 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of CDC42SE2 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] affects the expression of CDC42SE2 mRNA
CTD PMID:19684285 NCBI chr10:38,836,549...38,905,056
Ensembl chr10:38,836,555...38,905,059
JBrowse link
G Cdca5 cell division cycle associated 5 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of CDCA5 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CDCA5 mRNA
CTD PMID:19684285 NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023
JBrowse link
G Cdca7l cell division cycle associated 7 like multiple interactions ISO Cycloheximide inhibits the reaction [MLN7243 results in increased sumoylation of CDCA7L protein] CTD PMID:31285264 NCBI chr 6:138,793,953...138,839,889
Ensembl chr 6:138,794,228...138,839,888
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO Cycloheximide inhibits the reaction [Dexamethasone results in decreased expression of CDK2 mRNA] CTD PMID:12800980 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
decreases expression
ISO
EXP
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Cycloheximide results in decreased expression of CDKN1A protein]; Cycloheximide inhibits the reaction [Resveratrol results in increased expression of CDKN1A mRNA]; Cycloheximide inhibits the reaction [Troglitazone results in increased expression of CDKN1A protein]; Furazolidone promotes the reaction [Cycloheximide results in decreased expression of CDKN1A protein]; IGF1 protein inhibits the reaction [Cycloheximide results in decreased expression of CDKN1A protein]; PSME3 protein affects the reaction [Cycloheximide results in decreased expression of CDKN1A protein]
Cycloheximide promotes the reaction [Dexamethasone results in decreased expression of CDKN1A protein]; Cycloheximide promotes the reaction [Semaxinib results in increased expression of CDKN1A mRNA]
Cycloheximide inhibits the reaction [manganese chloride results in increased expression of CDKN1A protein]
Cycloheximide results in decreased expression of CDKN1A mRNA; Cycloheximide results in decreased expression of CDKN1A protein
CTD PMID:10441511 PMID:12690110 PMID:22542671 PMID:24211769 PMID:26687534 More... NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression ISO Cycloheximide results in increased expression of CDKN2A mRNA CTD PMID:17257637 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of CFLAR protein; Cycloheximide results in decreased expression of CFLAR protein alternative form; Cycloheximide results in decreased expression of CFLAR protein modified form
shogaol promotes the reaction [Cycloheximide results in decreased expression of CFLAR protein modified form]
CTD PMID:12663669 PMID:15924153 PMID:16077199 PMID:16951203 PMID:25619640 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Cftr CF transmembrane conductance regulator affects expression EXP Cycloheximide affects the expression of CFTR mRNA CTD PMID:17290305 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 multiple interactions ISO Cycloheximide inhibits the reaction [Dihydrotestosterone results in decreased expression of CHRM1 mRNA] CTD PMID:17624924 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356
JBrowse link
G Cish cytokine inducible SH2-containing protein increases expression ISO Cycloheximide results in increased expression of CISH mRNA CTD PMID:23237828 NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] affects the expression of CITED2 mRNA CTD PMID:19684285 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
JBrowse link
G Ckb creatine kinase B multiple interactions EXP Cycloheximide inhibits the reaction [Estradiol results in increased expression of CKB protein]; Cycloheximide inhibits the reaction [Methoxychlor results in increased expression of CKB protein] CTD PMID:7839363 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Clcn3 chloride voltage-gated channel 3 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CLCN3 mRNA CTD PMID:19684285 NCBI chr16:29,127,419...29,200,133
Ensembl chr16:29,127,419...29,200,119
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions ISO Cycloheximide inhibits the reaction [Dronabinol results in increased expression of CNR1 mRNA]; Cycloheximide inhibits the reaction [Morphine inhibits the reaction [TNF protein results in increased expression of CNR1 mRNA]]
Cycloheximide results in decreased expression of and affects the localization of CNR1 protein
CTD PMID:17041005 PMID:22258905 PMID:27513693 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Col10a1 collagen type X alpha 1 chain multiple interactions ISO Cycloheximide inhibits the reaction [Tretinoin results in increased expression of COL10A1 mRNA] CTD PMID:16350840 NCBI chr20:38,183,103...38,189,488
Ensembl chr20:38,182,494...38,189,494
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO Cycloheximide inhibits the reaction [[Genistein co-treated with Zinc Sulfate] results in increased expression of COL1A1 mRNA]; Cycloheximide inhibits the reaction [[Genistein co-treated with Zinc] results in increased expression of COL1A1 mRNA]; Cycloheximide inhibits the reaction [Cryptoxanthins results in increased expression of COL1A1 mRNA] CTD PMID:15962303 PMID:17203194 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO Cycloheximide inhibits the reaction [Thapsigargin affects the localization of CREB1 mRNA] CTD PMID:29576526 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crppa CDP-L-ribitol pyrophosphorylase A affects response to substance ISO CRPPA gene SNP affects the susceptibility to Cycloheximide CTD PMID:25622337 NCBI chr 6:53,120,264...53,397,030
Ensembl chr 6:53,121,438...53,397,028
JBrowse link
G Cryl1 crystallin, lambda 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CRYL1 mRNA CTD PMID:19684285 NCBI chr15:31,427,011...31,545,997
Ensembl chr15:31,427,054...31,545,997
JBrowse link
G Csf1 colony stimulating factor 1 multiple interactions ISO Cycloheximide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Cryptoxanthins] promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] promotes the reaction [Cryptoxanthins results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [Genistein promotes the reaction [[Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [Zinc results in increased expression of CSF1 mRNA] CTD PMID:12112025 PMID:17295206 PMID:18636177 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO Cycloheximide inhibits the reaction [IL1B results in increased secretion of CSF2 protein]; Cycloheximide inhibits the reaction [Particulate Matter results in increased secretion of CSF2 protein]; Cycloheximide inhibits the reaction [Vehicle Emissions results in increased secretion of CSF2 protein] CTD PMID:9606035 PMID:10645887 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Csnk1d casein kinase 1, delta multiple interactions ISO Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of CSNK1D mRNA] CTD PMID:11007951 NCBI chr10:106,221,992...106,256,620
Ensembl chr10:106,221,992...106,256,614
JBrowse link
G Ctnnb1 catenin beta 1 decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of CTNNB1 protein
Phenobarbital affects the reaction [Cycloheximide results in decreased expression of CTNNB1 protein]
CTD PMID:27693619 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctsb cathepsin B multiple interactions EXP Cycloheximide inhibits the reaction [Azithromycin results in increased activity of CTSB protein] CTD PMID:8830663 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Cul2 cullin 2 multiple interactions ISO CUL2 protein affects the reaction [Cycloheximide results in increased degradation of MAF1 protein] CTD PMID:31645432 NCBI chr17:54,169,086...54,210,197
Ensembl chr17:54,169,086...54,209,968
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO Cycloheximide inhibits the reaction [TNF protein results in increased expression of CXCL10 protein]; Cycloheximide inhibits the reaction [tofacitinib inhibits the reaction [TNF protein results in increased expression of CXCL10 protein]] CTD PMID:22121136 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CYCS mRNA] CTD PMID:11007951 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression EXP Cycloheximide results in decreased expression of CYP11A1 protein CTD PMID:21126571 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity
decreases expression
ISO
EXP
Cycloheximide results in decreased activity of CYP19A1 protein
Cycloheximide results in decreased expression of CYP19A1 protein
CTD PMID:16480277 PMID:21126571 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 affects expression
multiple interactions
increases expression
EXP
ISO
Cycloheximide affects the expression of CYP1A1 mRNA
[Cycloheximide results in increased activity of [AHR protein binds to ARNT protein]] which results in increased expression of CYP1A1 mRNA; [Piperonyl Butoxide co-treated with Cycloheximide] results in increased expression of CYP1A1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA]; Cycloheximide affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [6-(4-diethylamino)phenyl-7-chloro-5,8-quinolinedione results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [Cadmium Chloride results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [Copper results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [Lead results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [Mercury results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 enhancer]]; Cycloheximide promotes the reaction [Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1A1 enhancer]]; Cycloheximide promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [Semaxinib results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [sodium arsenite results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Dactinomycin promotes the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA]
3'-methoxy-4'-nitroflavone inhibits the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA]; [Cycloheximide co-treated with Harmaline] results in decreased expression of CYP1A1 protein; [Cycloheximide co-treated with harmalol] results in decreased expression of CYP1A1 protein; [Cycloheximide co-treated with Tetrachlorodibenzodioxin] results in increased expression of CYP1A1 mRNA; [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CYP1A1 mRNA; alpha-naphthoflavone inhibits the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA]; Benzimidazoles promotes the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Cycloheximide co-treated with Harmaline] results in decreased expression of CYP1A1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Cycloheximide co-treated with harmalol] results in decreased expression of CYP1A1 protein]; beta-Naphthoflavone promotes the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Cycloheximide inhibits the reaction [TGFB1 protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]]; Cycloheximide promotes the reaction [[Benzo(a)pyrene co-treated with Calcitriol] results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [Skatole results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
CTD PMID:1321828 PMID:1849469 PMID:1934297 PMID:2985607 PMID:8647108 More... NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO Cycloheximide affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA] CTD PMID:1849469 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression
multiple interactions
ISO
EXP
Cycloheximide results in increased expression of CYP1B1 mRNA
Cycloheximide inhibits the reaction [Vehicle Emissions results in increased expression of CYP1B1 protein]
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CYP1B1 mRNA; Cycloheximide inhibits the reaction [TGFB1 protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]]
CTD PMID:9145908 PMID:19684285 PMID:21867498 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Cycloheximide promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]]; Cycloheximide inhibits the reaction [Calcitriol results in increased expression of CYP24A1 mRNA] CTD PMID:19244278 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 increases expression ISO Cycloheximide results in increased expression of CYP2A5 mRNA CTD PMID:9007836 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases degradation
ISO
EXP
(4-amidinophenyl)methanesulfonyl fluoride inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; acetonitrile inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; Biotin inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; Carbon Tetrachloride promotes the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; Cycloheximide inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]; Cycloheximide promotes the reaction [Carbon Tetrachloride results in increased degradation of CYP2E1 protein]; Dimethyl Sulfoxide inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; Edetic Acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; Egtazic Acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; Ethanol inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; fomepizole inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; Glycerol inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; leupeptin inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Cycloheximide inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]; Tosyllysine Chloromethyl Ketone inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]
Cycloheximide inhibits the reaction [pyridine results in increased activity of CYP2E1 protein]; Cycloheximide inhibits the reaction [pyridine results in increased expression of CYP2E1 protein]
CTD PMID:1968335 PMID:8531136 PMID:9143349 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 multiple interactions ISO Cycloheximide inhibits the reaction [Skatole results in increased expression of CYP2F1 mRNA] CTD PMID:20187624 NCBI chr 1:82,416,108...82,429,897
Ensembl chr 1:82,416,130...82,429,896
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
decreases expression
EXP
ISO
Cycloheximide inhibits the reaction [pyridine results in increased expression of CYP3A2 mRNA]
Cycloheximide results in decreased expression of CYP3A4 mRNA
CTD PMID:11181506 PMID:21466820 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 multiple interactions EXP Cycloheximide inhibits the reaction [pyridine results in increased expression of CYP3A23-3A1 mRNA] CTD PMID:11181506 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Dag1 dystroglycan 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of DAG1 mRNA] CTD PMID:11007951 NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325
JBrowse link
G Dcn decorin multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of DCN mRNA] CTD PMID:11007951 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO Cycloheximide inhibits the reaction [plumbagin results in increased expression of DDIT3 protein] CTD PMID:31276663 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression
multiple interactions
EXP Cycloheximide results in increased expression of DDIT4 protein
[EGF protein co-treated with Cycloheximide] results in increased expression of DDIT4 protein
CTD PMID:22689575 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Deaf1 DEAF1 transcription factor multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of DEAF1 mRNA CTD PMID:19684285 NCBI chr 1:196,401,857...196,435,541
Ensembl chr 1:196,401,857...196,435,541
JBrowse link
G Degs1 delta(4)-desaturase, sphingolipid 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of DEGS1 mRNA] CTD PMID:11007951 NCBI chr13:93,946,154...93,953,677
Ensembl chr13:93,946,157...93,953,664
JBrowse link
G Dio2 iodothyronine deiodinase 2 multiple interactions
decreases activity
ISO [Cycloheximide co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] inhibits the reaction [2,2',4,4',5-brominated diphenyl ether metabolite results in decreased activity of DIO2 protein]; [Cycloheximide co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased activity of DIO2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased activity of DIO2 protein]; Cycloheximide promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [2,2',4,4',5-brominated diphenyl ether results in decreased activity of DIO2 protein]]; Cycloheximide promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Triiodothyronine, Reverse results in decreased activity of DIO2 protein]]; lactacystin inhibits the reaction [Cycloheximide results in decreased activity of DIO2 protein] CTD PMID:11425850 PMID:26004626 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
JBrowse link
G Dio3 iodothyronine deiodinase 3 multiple interactions EXP Cycloheximide inhibits the reaction [Hydrogen Peroxide results in increased activity of DIO3 protein] CTD PMID:18420745 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
JBrowse link
G Dnajb5 DnaJ heat shock protein family (Hsp40) member B5 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of DNAJB5 mRNA] CTD PMID:11007951 NCBI chr 5:57,176,840...57,185,492
Ensembl chr 5:57,176,845...57,185,490
JBrowse link
G Dnase1l3 deoxyribonuclease 1-like 3 increases expression ISO Cycloheximide results in increased expression of DNASE1L3 protein CTD PMID:15118903 NCBI chr15:16,922,335...16,948,322
Ensembl chr15:16,922,335...16,948,317
JBrowse link
G Dnm1l dynamin 1-like increases expression
multiple interactions
ISO Cycloheximide results in increased expression of DNM1L mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of DNM1L mRNA
CTD PMID:19684285 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions EXP [Cycloheximide co-treated with FASLG protein] results in decreased expression of DNMT3A mRNA; [Cycloheximide co-treated with FASLG protein] results in decreased expression of DNMT3A protein CTD PMID:19833194 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO [Cycloheximide co-treated with EDN1 protein] results in increased expression of ADRB2 mRNA CTD PMID:22483689 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ednra endothelin receptor type A multiple interactions EXP [Dimethyl Sulfoxide co-treated with Cycloheximide] results in decreased expression of EDNRA mRNA; [Dimethyl Sulfoxide co-treated with Cycloheximide] results in decreased expression of EDNRA protein; Cycloheximide inhibits the reaction [Particulate Matter results in increased expression of EDNRA mRNA]; Cycloheximide inhibits the reaction [Particulate Matter results in increased expression of EDNRA protein] CTD PMID:20561571 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Ednrb endothelin receptor type B multiple interactions EXP Cycloheximide inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; Cycloheximide inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; Cycloheximide inhibits the reaction [Particulate Matter results in increased expression of EDNRB mRNA]; Cycloheximide inhibits the reaction [Particulate Matter results in increased expression of EDNRB protein]; Cycloheximide inhibits the reaction [Smoke analog results in increased expression of EDNRB protein] CTD PMID:20561571 PMID:20716444 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
JBrowse link
G Egf epidermal growth factor multiple interactions EXP [EGF protein co-treated with Cycloheximide] results in increased expression of DDIT4 protein; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Arginine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Asparagine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Isoleucine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Leucine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Lysine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Methionine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Ornithine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Phenylalanine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Tyrosine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Valine]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein]]; Cycloheximide promotes the reaction [[EGF protein co-treated with Estradiol] results in increased expression of FOS mRNA] CTD PMID:12632255 PMID:22689575 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfr epidermal growth factor receptor increases expression
multiple interactions
ISO
EXP
Cycloheximide results in increased expression of EGFR mRNA
Cycloheximide promotes the reaction [Arsenic Trioxide results in decreased expression of EGFR protein]
Cycloheximide inhibits the reaction [Asbestos, Crocidolite results in increased expression of EGFR protein]
CTD PMID:15228094 PMID:26368632 PMID:30237564 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO Cycloheximide inhibits the reaction [resveratrol results in increased expression of EGR1 mRNA] CTD PMID:12690110 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Egr2 early growth response 2 increases expression ISO Cycloheximide results in increased expression of EGR2 mRNA CTD PMID:19350554 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A multiple interactions ISO Cycloheximide inhibits the reaction [orlistat results in increased phosphorylation of EIF2A protein] CTD PMID:17283163 NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions EXP Cycloheximide inhibits the reaction [dimethylarsinous acid results in increased phosphorylation of EIF2AK3 protein] CTD PMID:22425709 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases expression
increases phosphorylation
multiple interactions
ISO Cycloheximide results in increased expression of EIF2S1 mRNA
Cycloheximide results in increased phosphorylation of EIF2S1 protein
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of EIF2S1 mRNA
CTD PMID:19684285 PMID:24315374 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E multiple interactions ISO
EXP
Cycloheximide inhibits the reaction [EIF4E protein modified form inhibits the reaction [sodium arsenite results in decreased expression of CCND1 protein]]; Cycloheximide inhibits the reaction [EIF4E protein modified form inhibits the reaction [sodium arsenite results in decreased expression of ELAVL1 protein]]; Cycloheximide inhibits the reaction [EIF4E protein modified form inhibits the reaction [sodium arsenite results in decreased expression of MCL1 protein]]
Cycloheximide inhibits the reaction [EIF4EBP1 protein binds to EIF4E protein]
CTD PMID:22689575 PMID:25923732 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions EXP Cycloheximide inhibits the reaction [EIF4EBP1 protein binds to EIF4E protein]; Cycloheximide promotes the reaction [EIF4EBP1 protein binds to EIF4G1 protein] CTD PMID:22689575 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma, 1 multiple interactions EXP Cycloheximide promotes the reaction [EIF4EBP1 protein binds to EIF4G1 protein] CTD PMID:22689575 NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941
JBrowse link
G Eif4g3 eukaryotic translation initiation factor 4 gamma, 3 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of EIF4G3 mRNA] CTD PMID:11007951 NCBI chr 5:150,197,410...150,418,363
Ensembl chr 5:150,195,226...150,418,363
JBrowse link
G Eif5 eukaryotic translation initiation factor 5 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of EIF5 mRNA CTD PMID:19684285
G Elavl1 ELAV like RNA binding protein 1 multiple interactions ISO Cycloheximide inhibits the reaction [EIF4E protein modified form inhibits the reaction [sodium arsenite results in decreased expression of ELAVL1 protein]] CTD PMID:25923732 NCBI chr12:2,640,936...2,684,787
Ensembl chr12:2,645,061...2,684,784
JBrowse link
G Elf4 E74 like ETS transcription factor 4 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ELF4 mRNA] CTD PMID:11007951 NCBI chr  X:127,587,401...127,639,063
Ensembl chr  X:127,590,650...127,630,200
JBrowse link
G Elk1 ETS transcription factor ELK1 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of ELK1 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ELK1 mRNA
CTD PMID:19684285 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713
JBrowse link
G Eln elastin multiple interactions EXP Cycloheximide inhibits the reaction [Okadaic Acid results in decreased expression of ELN mRNA] CTD PMID:8997264 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928
JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of ELOVL3 mRNA
Cycloheximide inhibits the reaction [rosiglitazone results in increased expression of ELOVL3 mRNA]
CTD PMID:17726147 NCBI chr 1:244,997,287...245,001,115
Ensembl chr 1:244,997,287...245,001,115
JBrowse link
G Enc1 ectodermal-neural cortex 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of ENC1 mRNA CTD PMID:19684285 NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
JBrowse link
G Endog endonuclease G multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ENDOG mRNA] CTD PMID:11007951 NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932
JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions ISO Cycloheximide inhibits the reaction [cobaltous chloride results in increased expression of EPAS1 protein]; Cycloheximide inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:23958427 NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Epo erythropoietin multiple interactions ISO Cycloheximide inhibits the reaction [Oxygen deficiency results in increased expression of EPO mRNA] CTD PMID:10756076 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Epyc epiphycan multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of EPYC mRNA] CTD PMID:11007951 NCBI chr 7:32,436,620...32,474,326
Ensembl chr 7:32,436,620...32,474,135
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions
increases degradation
decreases expression
ISO [Cycloheximide co-treated with Estradiol] results in decreased expression of ERBB2 mRNA; Curcumin analog promotes the reaction [Cycloheximide results in increased degradation of ERBB2 protein]; PA2G4 protein promotes the reaction [Cycloheximide results in decreased expression of ERBB2 protein]
Cycloheximide results in decreased expression of ERBB2 mRNA; Cycloheximide results in decreased expression of ERBB2 protein
CTD PMID:15072547 PMID:15228094 PMID:20379846 PMID:25866362 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 decreases expression ISO Cycloheximide results in decreased expression of ERBB3 mRNA CTD PMID:15228094 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
JBrowse link
G Ereg epiregulin increases expression ISO Cycloheximide results in increased expression of EREG mRNA CTD PMID:15228094 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO Cycloheximide inhibits the reaction [Butyric Acid results in increased expression of ERN1 protein] CTD PMID:26784903 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
decreases expression
ISO bisphenol A promotes the reaction [Cycloheximide results in decreased expression of ESR1 protein]; Estradiol promotes the reaction [Cycloheximide results in decreased expression of ESR1 protein]; naringenin inhibits the reaction [Cycloheximide results in decreased expression of ESR1 protein] CTD PMID:24586459 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO Cycloheximide promotes the reaction [Estradiol results in increased expression of ESR2 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [Cycloheximide promotes the reaction [Estradiol results in increased expression of ESR2 mRNA]] CTD PMID:15207704 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Ext2 exostosin glycosyltransferase 2 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of EXT2 mRNA] CTD PMID:11007951 NCBI chr 3:79,665,415...79,798,077
Ensembl chr 3:79,665,415...79,798,059
JBrowse link
G F12 coagulation factor XII multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of F12 mRNA] CTD PMID:11007951 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530
JBrowse link
G F2 coagulation factor II multiple interactions ISO Cycloheximide inhibits the reaction [Simvastatin results in decreased activity of F2 protein] CTD PMID:14630613 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO Cycloheximide inhibits the reaction [Tretinoin results in decreased expression of F3 mRNA] CTD PMID:11876987 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Fas Fas cell surface death receptor multiple interactions
increases response to substance
ISO Cycloheximide promotes the reaction [FAS protein results in increased activity of CASP3 protein]; Cycloheximide promotes the reaction [FAS protein results in increased activity of CASP7 protein]; Cycloheximide promotes the reaction [FAS protein results in increased activity of CASP8 protein]
Cycloheximide results in increased susceptibility to FAS protein
CTD PMID:8932996 PMID:12760867 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand multiple interactions ISO
EXP
Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of FASLG mRNA]
[Cycloheximide co-treated with FASLG protein] results in decreased expression of DNMT3A mRNA; [Cycloheximide co-treated with FASLG protein] results in decreased expression of DNMT3A protein
CTD PMID:11007951 PMID:19833194 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO Cycloheximide inhibits the reaction [Calcitriol results in decreased expression of FASN mRNA] CTD PMID:12798352 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbl fibrillarin multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of FBL mRNA CTD PMID:19684285 NCBI chr 1:83,469,832...83,478,932
Ensembl chr 1:83,469,832...83,478,932
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 multiple interactions ISO Cycloheximide promotes the reaction [FBXW7 protein binds to and results in decreased expression of RICTOR protein] CTD PMID:25897075 NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941
JBrowse link
G Fga fibrinogen alpha chain decreases expression EXP Cycloheximide results in decreased expression of FGA protein CTD PMID:444225 NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528
JBrowse link
G Fgb fibrinogen beta chain decreases expression EXP Cycloheximide results in decreased expression of FGB protein CTD PMID:444225 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions EXP Cycloheximide inhibits the reaction [Dinoprost affects the localization of FGF2 protein]; Cycloheximide promotes the reaction [FGF2 protein results in increased expression of SERPINE1 mRNA] CTD PMID:9798919 PMID:15654655 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 multiple interactions EXP Cycloheximide inhibits the reaction [Triiodothyronine results in increased expression of FGFR1 mRNA] CTD PMID:12805413 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Fgl2 fibrinogen-like 2 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of FGL2 mRNA] CTD PMID:11007951 NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of FHIT mRNA CTD PMID:19684285 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
JBrowse link
G Fhl1 four and a half LIM domains 1 multiple interactions EXP Cycloheximide promotes the reaction [25-hydroxycholesterol results in increased expression of FHL1 mRNA] CTD PMID:17161435 NCBI chr  X:134,555,399...134,614,930
Ensembl chr  X:134,555,479...134,614,928
JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 increases expression ISO Cycloheximide results in increased expression of FMO3 mRNA CTD PMID:20570689 NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028
JBrowse link
G Fmr1 FMRP translational regulator 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of FMR1 mRNA CTD PMID:19684285 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO
EXP
Cycloheximide inhibits the reaction [Estradiol results in increased expression of FOS protein]; Cycloheximide inhibits the reaction [Genistein results in increased expression of FOS protein]; Cycloheximide inhibits the reaction [Quercetin results in increased expression of FOS protein]; Cycloheximide promotes the reaction [Cadmium Chloride results in increased expression of FOS mRNA]
Cycloheximide results in increased expression of FOS mRNA
Cycloheximide inhibits the reaction [NGF protein results in increased expression of FOS protein]
[Cycloheximide co-treated with Cadmium] results in increased expression of FOS mRNA; Cadmium Chloride promotes the reaction [Cycloheximide results in increased expression of FOS mRNA]; Cycloheximide inhibits the reaction [Hydrogen Peroxide results in increased expression of FOS protein]; Cycloheximide promotes the reaction [[EGF protein co-treated with Estradiol] results in increased expression of FOS mRNA]; Cycloheximide promotes the reaction [Cadmium Chloride results in increased expression of FOS mRNA]; Dactinomycin inhibits the reaction [[Cycloheximide co-treated with Cadmium] results in increased expression of FOS mRNA]
CTD PMID:1696944 PMID:9094091 PMID:9417049 PMID:9650640 PMID:12632255 More... NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Frk fyn-related Src family tyrosine kinase multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of FRK mRNA] CTD PMID:11007951 NCBI chr20:38,265,416...38,371,038
Ensembl chr20:38,265,280...38,371,114
JBrowse link
G Fst follistatin multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of FST mRNA] CTD PMID:11007951 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
JBrowse link
G Fut4 fucosyltransferase 4 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of FUT4 mRNA] CTD PMID:11007951 NCBI chr 8:11,586,721...11,590,682
Ensembl chr 8:11,586,721...11,590,682
JBrowse link
G Fzd7 frizzled class receptor 7 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of FZD7 mRNA] CTD PMID:11007951 NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions EXP Cycloheximide inhibits the reaction [Isoproterenol results in increased activity of G6PD protein] CTD PMID:1978808 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Galnt1 polypeptide N-acetylgalactosaminyltransferase 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of GALNT1 mRNA CTD PMID:19684285 NCBI chr18:15,489,015...15,568,849
Ensembl chr18:15,489,020...15,568,245
JBrowse link
G Gas1 growth arrest-specific 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of GAS1 mRNA] CTD PMID:11007951 NCBI chr17:4,482,014...4,485,155 JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO
EXP
Cycloheximide inhibits the reaction [arsenite results in increased activity of [GCLC protein binds to GCLM protein]]; Cycloheximide inhibits the reaction [arsenite results in increased expression of [GCLC protein binds to GCLM protein]]; Cycloheximide inhibits the reaction [arsenite results in increased expression of GCLC mRNA]; Cycloheximide inhibits the reaction [diphenylarsinic acid results in increased expression of GCLC protein]
Cycloheximide inhibits the reaction [notoginsenoside R1 results in increased expression of GCLC protein]
CTD PMID:17628625 PMID:19328227 PMID:24437944 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions ISO Cycloheximide inhibits the reaction [arsenite results in increased activity of [GCLC protein binds to GCLM protein]]; Cycloheximide inhibits the reaction [arsenite results in increased expression of [GCLC protein binds to GCLM protein]]; Cycloheximide inhibits the reaction [arsenite results in increased expression of GCLM mRNA] CTD PMID:19328227 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions ISO Cycloheximide inhibits the reaction [trichostatin A affects the expression of GDF15 mRNA]; Cycloheximide inhibits the reaction [trichostatin A affects the expression of GDF15 protein]; Cycloheximide inhibits the reaction [troglitazone results in increased expression of GDF15 mRNA] CTD PMID:14662774 PMID:18801729 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gpaa1 glycosylphosphatidylinositol anchor attachment 1 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of GPAA1 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of GPAA1 mRNA
CTD PMID:19684285 NCBI chr 7:108,051,896...108,055,479
Ensembl chr 7:108,051,861...108,055,484
JBrowse link
G Gpr37 G protein-coupled receptor 37 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of GPR37 mRNA] CTD PMID:11007951 NCBI chr 4:54,138,860...54,160,927
Ensembl chr 4:54,138,870...54,161,001
JBrowse link
G Grm5 glutamate metabotropic receptor 5 multiple interactions EXP Cycloheximide inhibits the reaction [Dextroamphetamine results in increased expression of GRM5 mRNA]; Cycloheximide inhibits the reaction [Dextroamphetamine results in increased expression of GRM5 protein] CTD PMID:11665859 NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274
JBrowse link
G Grn granulin precursor multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of GRN mRNA CTD PMID:19684285 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of GSK3B mRNA] CTD PMID:11007951 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 multiple interactions
decreases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Lead results in increased expression of GSTA1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Mercury results in increased expression of GSTA1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of GSTA1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide promotes the reaction [Copper results in decreased expression of GSTA1 mRNA]]; Cycloheximide inhibits the reaction [Lead results in increased expression of GSTA1 mRNA]; Cycloheximide inhibits the reaction [Mercury results in increased expression of GSTA1 mRNA]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of GSTA1 mRNA]; Cycloheximide promotes the reaction [Copper results in decreased expression of GSTA1 mRNA]
Cycloheximide results in decreased expression of GSTA1 mRNA
CTD PMID:16243960 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Gsta6 glutathione S-transferase alpha 6 decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of GSTA1 mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Lead results in increased expression of GSTA1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Mercury results in increased expression of GSTA1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of GSTA1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide promotes the reaction [Copper results in decreased expression of GSTA1 mRNA]]; Cycloheximide inhibits the reaction [Lead results in increased expression of GSTA1 mRNA]; Cycloheximide inhibits the reaction [Mercury results in increased expression of GSTA1 mRNA]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of GSTA1 mRNA]; Cycloheximide promotes the reaction [Copper results in decreased expression of GSTA1 mRNA]
CTD PMID:16243960 NCBI chr 9:23,743,262...23,806,260
Ensembl chr 9:23,744,288...23,801,131
JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO Cycloheximide results in increased expression of HBEGF mRNA CTD PMID:15228094 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases degradation
decreases expression
multiple interactions
ISO
EXP
Cycloheximide results in increased degradation of HIF1A protein
Cycloheximide results in decreased expression of HIF1A protein
Cycloheximide promotes the reaction [methylmercuric chloride results in decreased expression of HIF1A protein]
[Cycloheximide co-treated with cobaltous chloride] results in decreased expression of HIF1A protein; [Cycloheximide co-treated with INS protein] results in decreased expression of HIF1A protein; [Oxygen deficiency co-treated with Cycloheximide] affects the expression of HIF1A protein; Cycloheximide inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]; Cycloheximide inhibits the reaction [MLN7243 results in increased sumoylation of HIF1A protein]; Cycloheximide inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; Cycloheximide inhibits the reaction [Quercetin results in increased expression of HIF1A protein]; Cycloheximide inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]; Cycloheximide inhibits the reaction [sodium arsenite results in increased stability of HIF1A protein]; Cycloheximide inhibits the reaction [zinc chloride results in increased expression of HIF1A protein alternative form]; Cycloheximide promotes the reaction [Cobalt results in increased expression of HIF1A protein]; Cycloheximide promotes the reaction [nickel chloride results in increased expression of HIF1A protein]; genipin affects the reaction [[Oxygen deficiency co-treated with Cycloheximide] affects the expression of HIF1A protein]; L-4F peptide promotes the reaction [[Cycloheximide co-treated with cobaltous chloride] results in decreased expression of HIF1A protein]; L-4F peptide promotes the reaction [[Cycloheximide co-treated with INS protein] results in decreased expression of HIF1A protein]; scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose co-treated with Cycloheximide] results in decreased expression of HIF1A protein]; scutellarin promotes the reaction [Cycloheximide inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]
Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein]
CTD PMID:11641398 PMID:11739637 PMID:19958256 PMID:20524035 PMID:22537771 More... NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
decreases expression
ISO
EXP
Cycloheximide inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; Cycloheximide inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 mRNA]; Cycloheximide inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 protein]; Cycloheximide inhibits the reaction [Oxygen results in increased expression of HMOX1 mRNA]; Cycloheximide inhibits the reaction [Plant Extracts results in increased expression of HMOX1 protein]; Cycloheximide inhibits the reaction [resveratrol results in increased expression of HMOX1 mRNA]; Cycloheximide inhibits the reaction [resveratrol results in increased expression of HMOX1 protein]; Cycloheximide inhibits the reaction [tricarbonyldichlororuthenium (II) dimer results in increased expression of HMOX1 protein]; Cycloheximide results in decreased susceptibility to [surfactin peptide results in increased expression of HMOX1 protein]
Cycloheximide inhibits the reaction [cobaltous chloride results in increased expression of HMOX1 mRNA]; Cycloheximide inhibits the reaction [notoginsenoside R1 results in increased expression of HMOX1 protein]; Cycloheximide inhibits the reaction [Quercetin results in increased expression of HMOX1 protein]; Cycloheximide inhibits the reaction [resveratrol results in increased expression of HMOX1 protein]; Cycloheximide inhibits the reaction [sodium arsenite results in increased expression of HMOX1 protein]
Cycloheximide results in decreased expression of HMOX1 protein
Cycloheximide inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]; Cycloheximide inhibits the reaction [fisetin results in increased expression of HMOX1 protein]; Cycloheximide inhibits the reaction [puerarin results in increased expression of HMOX1 protein]; Cycloheximide inhibits the reaction [Quercetin results in increased expression of HMOX1 protein]; Cycloheximide inhibits the reaction [Triterpenes analog results in increased expression of HMOX1 protein]
CTD PMID:9747510 PMID:12441344 PMID:12472888 PMID:15118350 PMID:15588712 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnrnph2 heterogeneous nuclear ribonucleoprotein H2 increases expression ISO Cycloheximide results in increased expression of HNRNPH2 mRNA CTD PMID:19684285 NCBI chr  X:97,780,890...97,786,846
Ensembl chr  X:97,780,785...97,787,041
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K multiple interactions EXP Cycloheximide inhibits the reaction [Glycine results in increased expression of HNRNPK protein] CTD PMID:24990929 NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 multiple interactions ISO Cycloheximide promotes the reaction [Bexarotene results in increased expression of HSD11B2 mRNA]; Cycloheximide promotes the reaction [tributyltin results in increased expression of HSD11B2 mRNA]; Cycloheximide promotes the reaction [triphenyltin chloride results in increased expression of HSD11B2 mRNA] CTD PMID:31927052 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP
ISO
Cycloheximide inhibits the reaction [GIF 0010 results in increased expression of HSPA5 mRNA]; Cycloheximide inhibits the reaction [lead acetate results in increased expression of HSPA5 protein]; Cycloheximide inhibits the reaction [Mercuric Chloride results in increased expression of HSPA5 protein]
Cycloheximide inhibits the reaction [Butyric Acid results in increased expression of HSPA5 protein]; Cycloheximide inhibits the reaction [plumbagin results in increased expression of HSPA5 protein]
CTD PMID:9742210 PMID:17915553 PMID:26784903 PMID:31276663 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of HTATIP2 mRNA] CTD PMID:11007951 NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
decreases expression
ISO Cycloheximide inhibits the reaction [IFNG protein results in increased expression of ICAM1 protein]
Cycloheximide results in decreased expression of ICAM1 protein
CTD PMID:16087364 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ier3 immediate early response 3 multiple interactions ISO [afimoxifene co-treated with Cycloheximide] results in increased expression of IER3 mRNA CTD PMID:16849584 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Cycloheximide co-treated with IFNG protein] results in increased expression of PLAUR mRNA; Cycloheximide inhibits the reaction [IFNG protein results in increased expression of ICAM1 protein]; Cycloheximide inhibits the reaction [IFNG protein results in increased expression of TJP1 protein] CTD PMID:12070711 PMID:16087364 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ift27 intraflagellar transport 27 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of IFT27 mRNA] CTD PMID:11007951 NCBI chr 7:109,738,622...109,754,416
Ensembl chr 7:109,738,622...109,754,416
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO Cycloheximide inhibits the reaction [IGF1 protein affects the metabolism of 1,2-diacylglycerol]
IGF1 protein inhibits the reaction [Cycloheximide results in decreased expression of CDKN1A protein]
CTD PMID:2120207 PMID:26687534 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of IGFBP4 mRNA
[Cycloheximide co-treated with Estradiol] results in increased expression of IGFBP4 mRNA
CTD PMID:15072547 NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
JBrowse link
G Il10 interleukin 10 multiple interactions
decreases response to substance
increases expression
ISO
EXP
Cycloheximide inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA]
IL10 protein results in decreased susceptibility to Cycloheximide
Cycloheximide results in increased expression of IL10 mRNA
CTD PMID:19395591 PMID:22183712 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il17a interleukin 17A multiple interactions ISO Cycloheximide inhibits the reaction [Glucose results in increased secretion of IL17A protein] CTD PMID:18310510 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il18 interleukin 18 multiple interactions EXP Cycloheximide inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:18660453 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases expression
ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of IL1A mRNA
Cycloheximide results in increased expression of IL1A mRNA
CTD PMID:19684285 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
ISO
EXP
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of IL1B mRNA; Cycloheximide inhibits the reaction [CXCL8 protein affects the secretion of IL1B protein]; Cycloheximide inhibits the reaction [Dinoprostone promotes the reaction [IL1B protein results in increased expression of PTGS2 protein]]; Cycloheximide inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; Cycloheximide inhibits the reaction [IL1B results in increased secretion of CSF2 protein]; Cycloheximide inhibits the reaction [tetrachlorobenzoquinone results in increased expression of IL1B protein]; Cycloheximide inhibits the reaction [tetrachlorobenzoquinone results in increased secretion of IL1B protein modified form]
Cycloheximide promotes the reaction [IL1B protein results in increased expression of PTGS2 mRNA]
Cycloheximide results in increased expression of IL1B mRNA
CTD PMID:8071060 PMID:9606035 PMID:11112151 PMID:11286988 PMID:19684285 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il5 interleukin 5 decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of IL5 protein
TO-901317 inhibits the reaction [Cycloheximide results in decreased expression of IL5 protein]
CTD PMID:23150660 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
decreases secretion
increases secretion
ISO Cycloheximide inhibits the reaction [CXCL8 protein affects the secretion of IL6 protein]; TNF protein promotes the reaction [Cycloheximide results in increased expression of IL6 mRNA]; TNF protein promotes the reaction [Cycloheximide results in increased secretion of IL6 protein]; Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of IL6 mRNA]]; Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased secretion of IL6 protein]]
Cycloheximide results in decreased secretion of IL6 protein
CTD PMID:8071060 PMID:11216681 PMID:12185005 PMID:21146893 PMID:24771768 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6st interleukin 6 cytokine family signal transducer multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IL6ST mRNA] CTD PMID:11007951 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936
JBrowse link
G Ins2 insulin 2 multiple interactions ISO [Cycloheximide co-treated with INS protein] results in decreased expression of HIF1A protein; L-4F peptide promotes the reaction [[Cycloheximide co-treated with INS protein] results in decreased expression of HIF1A protein] CTD PMID:22537771 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IQGAP1 mRNA] CTD PMID:11007951 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
JBrowse link
G Irs1 insulin receptor substrate 1 decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of IRS1 mRNA
[Cycloheximide co-treated with Estradiol] results in increased expression of IRS1 mRNA
CTD PMID:15072547 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Itgb3 integrin subunit beta 3 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ITGB3 mRNA] CTD PMID:11007951 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Itgb6 integrin subunit beta 6 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ITGB6 mRNA]; Cycloheximide inhibits the reaction [TGFB1 protein results in increased expression of ITGB6 mRNA] CTD PMID:11007951 PMID:21303922 NCBI chr 3:45,046,295...45,170,532
Ensembl chr 3:45,048,044...45,121,671
JBrowse link
G Itpk1 inositol-tetrakisphosphate 1-kinase multiple interactions ISO ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased activity of CASP9 protein]; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP3 protein]; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP8 protein]; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of BID protein]; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of PARP1 protein]; ITPK1 mutant form promotes the reaction [[Cycloheximide co-treated with TNF protein] results in increased cleavage of BID protein]; ITPK1 mutant form promotes the reaction [[Cycloheximide co-treated with TNF protein] results in increased cleavage of PARP1 protein]; ITPK1 mutant form results in increased susceptibility to [Cycloheximide co-treated with TNF protein] CTD PMID:12925536 NCBI chr 6:121,710,750...121,844,501
Ensembl chr 6:121,710,755...121,844,107
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 multiple interactions ISO Cycloheximide inhibits the reaction [Ethanol results in increased expression of ITPR1 mRNA]; Cycloheximide inhibits the reaction [linsidomine results in increased expression of ITPR1 mRNA]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ITPR1 mRNA] CTD PMID:11007951 PMID:17241155 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
JBrowse link
G Ivns1abp influenza virus NS1A binding protein multiple interactions ISO Cycloheximide inhibits the reaction [Doxorubicin results in decreased expression of IVNS1ABP mRNA] CTD PMID:17016628 NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases stability
increases phosphorylation
multiple interactions
EXP
ISO
Cycloheximide results in increased stability of JUN protein
Cycloheximide results in increased phosphorylation of JUN protein
Cycloheximide promotes the reaction [Cadmium results in increased expression of JUN mRNA]
Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of JUN protein]
CTD PMID:1696944 PMID:9751194 PMID:12169099 PMID:23593480 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kank1 KN motif and ankyrin repeat domains 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of KANK1 mRNA CTD PMID:19684285 NCBI chr 1:222,877,962...223,074,514
Ensembl chr 1:222,877,622...223,074,514
JBrowse link
G Kng2 kininogen 2 multiple interactions EXP Cycloheximide inhibits the reaction [KNG1 protein results in increased phosphorylation of MAPK1 protein]; Cycloheximide inhibits the reaction [KNG1 protein results in increased phosphorylation of MAPK3 protein]; Cycloheximide inhibits the reaction [KNG1 protein results in increased phosphorylation of PTGS2 protein]; Cycloheximide inhibits the reaction [KNG1 protein results in increased secretion of TAC1 protein] CTD PMID:16696851 NCBI chr11:77,913,876...77,936,247 JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of KRAS mRNA] CTD PMID:11007951 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Kremen1 kringle containing transmembrane protein 1 affects response to substance ISO KREMEN1 gene SNP affects the susceptibility to Cycloheximide CTD PMID:25622337 NCBI chr14:80,081,870...80,147,489
Ensembl chr14:80,084,403...80,147,516
JBrowse link
G Krt13 keratin 13 multiple interactions ISO [afimoxifene co-treated with Cycloheximide] results in increased expression of KRT13 mRNA CTD PMID:16849584 NCBI chr10:85,052,122...85,056,032
Ensembl chr10:85,051,889...85,056,084
JBrowse link
G Krtcap2 keratinocyte associated protein 2 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of KRTCAP2 mRNA CTD PMID:19684285 NCBI chr 2:174,654,409...174,658,405
Ensembl chr 2:174,654,219...174,658,405
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of LCK mRNA] CTD PMID:11007951 NCBI chr 5:141,888,319...141,916,992
Ensembl chr 5:141,888,326...141,903,794
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions
decreases expression
ISO Cycloheximide inhibits the reaction [Quercetin results in increased expression of LDLR protein]
Cycloheximide results in decreased expression of LDLR protein
CTD PMID:22388943 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lep leptin multiple interactions ISO LEP protein inhibits the reaction [Cycloheximide results in decreased expression of LEPR protein] CTD PMID:31199479 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lepr leptin receptor multiple interactions
decreases expression
ISO LEP protein inhibits the reaction [Cycloheximide results in decreased expression of LEPR protein] CTD PMID:31199479 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Lgals3 galectin 3 multiple interactions ISO Cycloheximide inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of LGALS3 protein] CTD PMID:21821001 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions EXP Cycloheximide promotes the reaction [LHB protein results in increased expression of NR4A1 mRNA] CTD PMID:11416027 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Lmo7 LIM domain 7 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of LMO7 mRNA] CTD PMID:11007951 NCBI chr15:78,567,029...78,769,833
Ensembl chr15:78,567,023...78,769,783
JBrowse link
G Lpxn leupaxin multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of LPXN mRNA] CTD PMID:11007951 NCBI chr 1:209,928,297...209,963,085
Ensembl chr 1:209,929,202...209,963,084
JBrowse link
G Maf1 MAF1 homolog, negative regulator of RNA polymerase III increases degradation
multiple interactions
ISO Cycloheximide results in increased degradation of MAF1 protein
Bortezomib inhibits the reaction [Cycloheximide results in increased degradation of MAF1 protein]; CUL2 protein affects the reaction [Cycloheximide results in increased degradation of MAF1 protein]; Cycloheximide inhibits the reaction [Sirolimus results in increased expression of MAF1 protein]; PSMD1 protein affects the reaction [Cycloheximide results in increased degradation of MAF1 protein]
CTD PMID:31645432 NCBI chr 7:108,075,173...108,078,252
Ensembl chr 7:108,075,189...108,078,249
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions
increases activity
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cycloheximide results in increased expression of MAP2K1 mRNA]
Cycloheximide results in increased activity of MAP2K1 protein
CTD PMID:23237828 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO
EXP
Cycloheximide results in increased phosphorylation of MAPK1 protein
Cycloheximide inhibits the reaction [KNG1 protein results in increased phosphorylation of MAPK1 protein]; Cycloheximide promotes the reaction [[sodium arsenite co-treated with Hydrogen Peroxide] results in increased phosphorylation of MAPK1 protein]
Cycloheximide inhibits the reaction [Cyclosporine results in increased phosphorylation of MAPK1 protein]; Pertussis Toxin inhibits the reaction [TAS2R105 protein affects the reaction [Cycloheximide results in increased phosphorylation of MAPK1 protein]]
CTD PMID:12472888 PMID:15087236 PMID:16696851 PMID:22155090 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO Cycloheximide inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of MAPK14 protein] CTD PMID:17507666 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO
EXP
Cycloheximide results in increased phosphorylation of MAPK3 protein
Cycloheximide inhibits the reaction [KNG1 protein results in increased phosphorylation of MAPK3 protein]; Cycloheximide promotes the reaction [sodium arsenite promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]]
Cycloheximide inhibits the reaction [Cyclosporine results in increased phosphorylation of MAPK3 protein]; Pertussis Toxin inhibits the reaction [TAS2R105 protein affects the reaction [Cycloheximide results in increased phosphorylation of MAPK3 protein]]
CTD PMID:12472888 PMID:15087236 PMID:16696851 PMID:22155090 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 multiple interactions
increases expression
ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of MAPK7 mRNA; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MAPK7 mRNA]
Cycloheximide results in increased expression of MAPK7 mRNA
CTD PMID:11007951 PMID:19684285 NCBI chr10:46,170,264...46,176,262
Ensembl chr10:46,170,167...46,176,267
JBrowse link
G Mapkapk3 MAPK activated protein kinase 3 affects response to substance ISO MAPKAPK3 gene SNP affects the susceptibility to Cycloheximide CTD PMID:25622337 NCBI chr 8:107,929,754...107,963,638
Ensembl chr 8:107,929,762...107,963,568
JBrowse link
G Mbp myelin basic protein affects expression EXP Cycloheximide affects the expression of MBP mRNA CTD PMID:22954530 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member multiple interactions
decreases expression
ISO [Cycloheximide co-treated with MCL1] results in increased susceptibility to ABT-737; [resveratrol co-treated with clofarabine co-treated with Cycloheximide] results in decreased expression of MCL1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of MCL1 protein]; Cycloheximide inhibits the reaction [EIF4E protein modified form inhibits the reaction [sodium arsenite results in decreased expression of MCL1 protein]] CTD PMID:14982947 PMID:21880625 PMID:24924397 PMID:25408576 PMID:25923732 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mdk midkine multiple interactions ISO Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of MDK mRNA] CTD PMID:11007951 NCBI chr 3:77,901,156...77,903,997
Ensembl chr 3:77,901,158...77,903,130
JBrowse link
G Mir21 microRNA 21 multiple interactions
increases expression
ISO Cycloheximide inhibits the reaction [Dihydrotestosterone results in increased expression of MIR21 mRNA]; Cycloheximide inhibits the reaction [Estradiol results in decreased expression of MIR21 mRNA]; Cycloheximide inhibits the reaction [fludioxonil results in increased expression of MIR21 mRNA]; Cycloheximide inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of MIR21 mRNA]
Cycloheximide results in increased expression of MIR21 mRNA
CTD PMID:19264808 PMID:23052036 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mitf melanocyte inducing transcription factor multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Cycloheximide co-treated with 4-(1-phenylethyl)-1,3-benzenediol] results in increased degradation of MITF protein]; [Cycloheximide co-treated with 4-(1-phenylethyl)-1,3-benzenediol] results in increased degradation of MITF protein CTD PMID:30849679 NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO Cycloheximide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 protein]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA] CTD PMID:15075337 PMID:19136476 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp13 matrix metallopeptidase 13 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of MMP13 mRNA
Cycloheximide inhibits the reaction [Tretinoin results in increased expression of MMP13 mRNA]
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of MMP13 mRNA
CTD PMID:16350840 PMID:19684285 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO Cycloheximide inhibits the reaction [Vehicle Emissions results in increased expression of MMP2 mRNA] CTD PMID:26621329 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mnx1 motor neuron and pancreas homeobox 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of MNX1 mRNA] CTD PMID:11007951 NCBI chr 4:5,866,506...5,871,465
Ensembl chr 4:5,866,506...5,871,465
JBrowse link
G Mpg N-methylpurine-DNA glycosylase multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MPG mRNA] CTD PMID:11007951 NCBI chr10:15,396,246...15,402,528
Ensembl chr10:15,395,782...15,402,520
JBrowse link
G Mrps7 mitochondrial ribosomal protein S7 decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of MRPS7 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] affects the expression of MRPS7 mRNA
CTD PMID:19684285 NCBI chr10:100,843,691...100,846,838
Ensembl chr10:100,843,356...100,847,129
JBrowse link
G Msh3 mutS homolog 3 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of MSH3 mRNA] CTD PMID:11007951 NCBI chr 2:23,444,326...23,585,777 JBrowse link
G Msr1 macrophage scavenger receptor 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA] CTD PMID:9614211 NCBI chr16:52,717,775...52,802,890
Ensembl chr16:52,717,732...52,799,676
JBrowse link
G Mt1 metallothionein 1 multiple interactions
increases expression
ISO 2-tert-butylhydroquinone promotes the reaction [Cycloheximide results in increased expression of MT1 mRNA]; Cycloheximide promotes the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]; Cycloheximide promotes the reaction [arsenic trichloride results in increased expression of MT1 mRNA]; MTF1 protein affects the reaction [Cycloheximide promotes the reaction [arsenic trichloride results in increased expression of MT1 mRNA]]; MTF1 protein affects the reaction [Cycloheximide results in increased expression of MT1 mRNA] CTD PMID:14998373 PMID:19276070 NCBI chr19:10,826,032...10,827,048 JBrowse link
G Mtch2 mitochondrial carrier 2 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of MTCH2 mRNA CTD PMID:19684285 NCBI chr 3:76,830,549...76,850,189
Ensembl chr 3:76,830,413...76,850,189
JBrowse link
G Mtf1 metal-regulatory transcription factor 1 multiple interactions ISO MTF1 protein affects the reaction [Cycloheximide promotes the reaction [arsenic trichloride results in increased expression of MT1 mRNA]]; MTF1 protein affects the reaction [Cycloheximide results in increased expression of MT1 mRNA] CTD PMID:19276070 NCBI chr 5:137,062,319...137,107,136
Ensembl chr 5:137,062,376...137,107,136
JBrowse link
G Mtmr7 myotubularin related protein 7 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of MTMR7 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of MTMR7 mRNA
CTD PMID:19684285 NCBI chr16:51,641,225...51,732,212
Ensembl chr16:51,641,190...51,732,182
JBrowse link
G Mxd1 max dimerization protein 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MXD1 mRNA] CTD PMID:11007951 NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751
JBrowse link
G Mxd3 Max dimerization protein 3 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of MXD3 mRNA CTD PMID:19684285 NCBI chr17:9,301,430...9,305,156
Ensembl chr17:9,301,399...9,305,157
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO
EXP
Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MYC protein]
Cycloheximide inhibits the reaction [MLN7243 results in increased sumoylation of MYC protein]
Cycloheximide promotes the reaction [Cadmium results in increased expression of MYC mRNA]
CTD PMID:1696944 PMID:23593480 PMID:31285264 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Mylk myosin light chain kinase multiple interactions ISO Cycloheximide inhibits the reaction [TNF protein results in increased expression of MYLK protein] CTD PMID:15701621 NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261
JBrowse link
G Myo1d myosin ID affects response to substance ISO MYO1D gene SNP affects the susceptibility to Cycloheximide CTD PMID:25622337 NCBI chr10:65,489,153...65,765,812
Ensembl chr10:65,489,154...65,766,349
JBrowse link
G Nbr1 NBR1, autophagy cargo receptor increases expression
multiple interactions
ISO Cycloheximide results in increased expression of NBR1 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of NBR1 mRNA
CTD PMID:19684285 NCBI chr10:86,477,775...86,506,418
Ensembl chr10:86,478,290...86,506,412
JBrowse link
G Ndrg1 N-myc downstream regulated 1 multiple interactions
decreases expression
ISO Chloroquine inhibits the reaction [Cycloheximide results in decreased expression of NDRG1 protein] CTD PMID:28906492 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of NEDD4 protein
Melatonin promotes the reaction [Cycloheximide results in decreased expression of NEDD4 protein]
CTD PMID:31325559 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
JBrowse link
G Nefh neurofilament heavy chain decreases expression EXP Cycloheximide results in decreased expression of NEFH mRNA CTD PMID:19146868 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
JBrowse link
G Nefl neurofilament light chain decreases expression EXP Cycloheximide results in decreased expression of NEFL mRNA CTD PMID:19146868 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
JBrowse link
G Nek2 NIMA-related kinase 2 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of NEK2 mRNA] CTD PMID:11007951 NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
decreases expression
ISO [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Cycloheximide] results in increased expression of NFE2L2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Particulate Matter analog results in increased expression of NFE2L2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Vehicle Emissions analog results in increased expression of NFE2L2 protein]]; Cycloheximide inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased activity of NFE2L2 protein]; Cycloheximide inhibits the reaction [Particulate Matter analog results in increased expression of NFE2L2 protein]; Cycloheximide inhibits the reaction [Vehicle Emissions analog results in increased expression of NFE2L2 protein]; exenatide inhibits the reaction [Cycloheximide results in decreased expression of NFE2L2 protein]
[SB 203580 co-treated with Cycloheximide] inhibits the reaction [Quercetin results in decreased expression of NFE2L2 protein]; Cycloheximide inhibits the reaction [[SB 203580 co-treated with Quercetin] results in increased expression of NFE2L2 protein]; Cycloheximide inhibits the reaction [Quercetin results in increased expression of NFE2L2 protein]; Cycloheximide inhibits the reaction [SB 203580 affects the reaction [Quercetin affects the localization of NFE2L2 protein]]; Cycloheximide inhibits the reaction [sulforaphane results in increased expression of NFE2L2 protein]
CTD PMID:12441344 PMID:14510636 PMID:15322212 PMID:22019695 PMID:22197970 More... NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 affects localization
multiple interactions
increases expression
ISO Cycloheximide affects the localization of NFKB1 protein
Cycloheximide results in decreased expression of [NFKB1 protein binds to RELA protein]; TNF protein promotes the reaction [Cycloheximide results in increased expression of NFKB1 mRNA]; Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of NFKB1 mRNA]]
CTD PMID:16637064 PMID:21146893 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
decreases expression
increases degradation
ISO Cycloheximide inhibits the reaction [Morphine results in increased expression of NFKBIA mRNA]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NFKBIA mRNA]; Cycloheximide promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of NFKBIA protein]; Cycloheximide promotes the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; NFKBIA protein affects the reaction [Cycloheximide promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of SAT1 mRNA]]; Tetradecanoylphorbol Acetate promotes the reaction [Cycloheximide results in decreased expression of NFKBIA protein]; Tetradecanoylphorbol Acetate promotes the reaction [Cycloheximide results in increased degradation of NFKBIA protein] CTD PMID:11007951 PMID:15330761 PMID:16637064 PMID:21692457 PMID:22258905 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Ngf nerve growth factor multiple interactions ISO Cycloheximide inhibits the reaction [NGF protein results in increased expression of FOS protein]; Cycloheximide inhibits the reaction [NGF protein results in increased expression of SOD2 protein] CTD PMID:20495008 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO Cycloheximide inhibits the reaction [tetrachlorobenzoquinone results in increased expression of NLRP3 protein] CTD PMID:26901245 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Cycloheximide inhibits the reaction [Cyclosporine results in increased expression of NOS2 protein]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NOS2 mRNA] CTD PMID:10760090 PMID:11007951 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NOS3 mRNA] CTD PMID:11007951 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Npy1r neuropeptide Y receptor Y1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of NPY1R mRNA] CTD PMID:11007951 NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression
multiple interactions
ISO
EXP
Cycloheximide results in decreased expression of NQO1 mRNA
Cycloheximide inhibits the reaction [notoginsenoside R1 results in increased expression of NQO1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Lead results in increased expression of NQO1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide promotes the reaction [Copper results in decreased expression of NQO1 mRNA]]; Cycloheximide inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; Cycloheximide inhibits the reaction [arsenite results in increased expression of NQO1 mRNA]; Cycloheximide inhibits the reaction [Cadmium results in increased expression of NQO1 mRNA]; Cycloheximide inhibits the reaction [Lead results in increased expression of NQO1 mRNA]; Cycloheximide inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Cycloheximide promotes the reaction [Chromium results in increased expression of NQO1 mRNA]; Cycloheximide promotes the reaction [Copper results in decreased expression of NQO1 mRNA]
CTD PMID:14510636 PMID:16243960 PMID:18474416 PMID:24437944 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 multiple interactions ISO Cycloheximide inhibits the reaction [Bucladesine results in decreased expression of NR0B1 mRNA]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of NR0B1 mRNA] CTD PMID:18787026 NCBI chr  X:50,756,886...50,761,014
Ensembl chr  X:50,756,886...50,761,011
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions
increases expression
ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of NR1H3 mRNA
Cycloheximide results in increased expression of NR1H3 mRNA
CTD PMID:19684285 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO
EXP
Cycloheximide inhibits the reaction [Dexamethasone affects the localization of NR3C1 protein]; Cycloheximide inhibits the reaction [Dexamethasone binds to NR3C1 protein]; Cycloheximide inhibits the reaction [Dexamethasone results in increased degradation of NR3C1 protein]
Cycloheximide promotes the reaction [tubacin results in decreased expression of and results in increased degradation of NR3C1 mRNA]
CTD PMID:21569845 PMID:31778773 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions EXP Cycloheximide promotes the reaction [LHB protein results in increased expression of NR4A1 mRNA] CTD PMID:11416027 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of NUCKS1 mRNA CTD PMID:19684285 NCBI chr13:43,345,091...43,374,316
Ensembl chr13:43,345,115...43,370,229
JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions ISO Cycloheximide inhibits the reaction [Paraquat results in increased activity of ODC1 protein] CTD PMID:7662713 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions EXP Cycloheximide inhibits the reaction [15-deoxyprostaglandin J2 results in increased expression of OPA1 protein alternative form] CTD PMID:20678484 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Oprk1 opioid receptor, kappa 1 multiple interactions
increases expression
ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of OPRK1 mRNA
Cycloheximide results in increased expression of OPRK1 mRNA
CTD PMID:19684285 NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823
JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions ISO Cycloheximide inhibits the reaction [Dronabinol results in increased expression of OPRM1 mRNA] CTD PMID:16434616 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G Orm1 orosomucoid 1 multiple interactions EXP Cycloheximide inhibits the reaction [Dexamethasone results in increased expression of ORM1 mRNA] CTD PMID:20599767 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154
JBrowse link
G Pa2g4 proliferation-associated 2G4 multiple interactions ISO PA2G4 protein promotes the reaction [Cycloheximide results in decreased expression of ERBB2 protein] CTD PMID:20379846 NCBI chr 7:984,795...992,264
Ensembl chr 7:983,971...992,331
JBrowse link
G Pappa1 pappalysin 1 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of PAPPA mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PAPPA mRNA
CTD PMID:19684285 NCBI chr 5:78,497,660...78,735,873
Ensembl chr 5:78,498,300...78,730,666
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
ISO
EXP
[Cycloheximide co-treated with TNF protein] results in increased cleavage of PARP1 protein; [Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of PARP1 protein]; ITPK1 mutant form promotes the reaction [[Cycloheximide co-treated with TNF protein] results in increased cleavage of PARP1 protein]
Cycloheximide inhibits the reaction [ammonium acetate results in increased expression of PARP1 protein]
Cycloheximide results in increased cleavage of PARP1 protein
CTD PMID:12925536 PMID:15147502 PMID:16051428 PMID:18222423 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pax3 paired box 3 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PAX3 mRNA] CTD PMID:11007951 NCBI chr 9:79,567,455...79,664,042
Ensembl chr 9:79,568,634...79,664,042
JBrowse link
G Pcgf1 polycomb group ring finger 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PCGF1 mRNA CTD PMID:19684285 NCBI chr 4:115,576,165...115,587,019
Ensembl chr 4:115,583,867...115,587,008
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO Cycloheximide inhibits the reaction [Dexamethasone results in decreased expression of PCK1 mRNA] CTD PMID:9518257 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO Cycloheximide inhibits the reaction [Vitamin K 3 results in decreased expression of PCNA protein] CTD PMID:21533478 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pdcd2 programmed cell death 2 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PDCD2 mRNA] CTD PMID:11007951 NCBI chr 1:56,484,947...56,490,437
Ensembl chr 1:56,463,931...56,490,437
JBrowse link
G Pi4ka phosphatidylinositol 4-kinase alpha multiple interactions ISO Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of PI4KA mRNA] CTD PMID:11007951 NCBI chr11:83,609,136...83,726,876
Ensembl chr11:83,609,069...83,724,080
JBrowse link
G Pigh phosphatidylinositol glycan anchor biosynthesis, class H multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PIGH mRNA] CTD PMID:11007951 NCBI chr 6:97,874,903...97,897,188
Ensembl chr 6:97,882,903...97,897,142
JBrowse link
G Pigk phosphatidylinositol glycan anchor biosynthesis, class K multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PIGK mRNA] CTD PMID:11007951 NCBI chr 2:241,630,021...241,715,493
Ensembl chr 2:241,630,053...241,716,134
JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PIK3C3 mRNA] CTD PMID:11007951 NCBI chr18:21,845,282...21,934,387
Ensembl chr18:21,845,295...21,929,048
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PIK3CG mRNA] CTD PMID:11007951 NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043
JBrowse link
G Pilrb paired immunoglobin-like type 2 receptor beta multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PILRB mRNA CTD PMID:19684285 NCBI chr12:18,516,161...18,525,375
Ensembl chr12:18,516,156...18,525,346
JBrowse link
G Pla2g1b phospholipase A2 group IB multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PLA2G1B mRNA] CTD PMID:11007951 NCBI chr12:41,142,193...41,151,967
Ensembl chr12:41,142,200...41,153,226
JBrowse link
G Pla2g4a phospholipase A2 group IVA multiple interactions ISO Cycloheximide inhibits the reaction [Dexamethasone inhibits the reaction [Zymosan results in increased activity of PLA2G4A protein]] CTD PMID:10874129 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Plat plasminogen activator, tissue type multiple interactions EXP Cycloheximide promotes the reaction [Isoproterenol results in increased expression of PLAT mRNA] CTD PMID:2477232 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Plaur plasminogen activator, urokinase receptor multiple interactions
increases expression
ISO [Cycloheximide co-treated with IFNA2 protein] results in increased expression of PLAUR mRNA; [Cycloheximide co-treated with IFNG protein] results in increased expression of PLAUR mRNA
Cycloheximide results in increased expression of PLAUR mRNA
CTD PMID:12070711 NCBI chr 1:80,053,441...80,068,384
Ensembl chr 1:80,050,324...80,068,595
JBrowse link
G Pld3 phospholipase D family, member 3 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of PLD3 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PLD3 mRNA
CTD PMID:19684285 NCBI chr 1:82,821,863...82,844,280
Ensembl chr 1:82,821,875...82,844,072
JBrowse link
G Pln phospholamban multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PLN mRNA] CTD PMID:11007951 NCBI chr20:32,629,537...32,639,559 JBrowse link
G Plp1 proteolipid protein 1 multiple interactions
increases expression
EXP Cycloheximide promotes the reaction [Tretinoin results in increased expression of PLP1 mRNA]
Cycloheximide results in increased expression of PLP1 mRNA
CTD PMID:19450544 NCBI chr  X:100,184,039...100,201,035
Ensembl chr  X:100,185,767...100,201,032
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 multiple interactions ISO Cycloheximide inhibits the reaction [Fenretinide results in increased expression of PMAIP1 protein]; Cycloheximide inhibits the reaction [Thapsigargin results in increased expression of PMAIP1 protein] CTD PMID:17216584 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Pml PML nuclear body scaffold decreases degradation
multiple interactions
ISO Cycloheximide results in decreased degradation of PML protein modified form
Cycloheximide inhibits the reaction [arsenic trioxide results in increased degradation of PML protein]
CTD PMID:20943951 PMID:26049103 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 multiple interactions ISO Cycloheximide inhibits the reaction [rosiglitazone results in increased expression of PNPLA2 protein] CTD PMID:18643838 NCBI chr 1:196,552,723...196,557,805
Ensembl chr 1:196,552,723...196,557,805
JBrowse link
G Pnpla6 patatin-like phospholipase domain containing 6 multiple interactions ISO Cycloheximide inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of PNPLA6 protein]; Cycloheximide inhibits the reaction [Bucladesine results in increased activity of PNPLA6 protein]; Cycloheximide inhibits the reaction [Colforsin results in increased activity of PNPLA6 protein] CTD PMID:20380879 NCBI chr12:1,574,387...1,603,735
Ensembl chr12:1,560,363...1,603,734
JBrowse link
G Pomc proopiomelanocortin multiple interactions EXP Cycloheximide inhibits the reaction [POMC protein modified form results in increased chemical synthesis of Adrenal Cortex Hormones] CTD PMID:2993719 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions
decreases expression
ISO POR protein mutant form promotes the reaction [Cycloheximide results in decreased expression of POR protein] CTD PMID:27496950 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Pou5f1 POU class 5 homeobox 1 multiple interactions ISO Cycloheximide promotes the reaction [Cobalt results in increased expression of POU5F1 protein]; Cycloheximide promotes the reaction [nickel chloride results in increased expression of POU5F1 protein] CTD PMID:24497960 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Ppan peter pan homolog multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PPAN mRNA CTD PMID:19684285 NCBI chr 8:19,423,908...19,427,941
Ensembl chr 8:19,423,961...19,427,938
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of PPP1R15A protein
arsenite inhibits the reaction [Cycloheximide results in decreased expression of PPP1R15A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of PPP1R15A protein]; Cycloheximide affects the reaction [arsenite results in increased expression of PPP1R15A protein]; Cycloheximide inhibits the reaction [Thapsigargin results in increased expression of PPP1R15A protein]
CTD PMID:29109149 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PPP3CB mRNA] CTD PMID:11007951 NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981
JBrowse link
G Ppp4r3b protein phosphatase 4, regulatory subunit 3B multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PPP4R3B mRNA CTD PMID:19684285 NCBI chr14:102,917,043...102,965,210
Ensembl chr14:102,917,443...103,068,192
JBrowse link
G Prdx4 peroxiredoxin 4 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PRDX4 mRNA] CTD PMID:11007951 NCBI chr  X:40,026,762...40,044,066
Ensembl chr  X:40,026,651...40,044,066
JBrowse link
G Prkcb protein kinase C, beta decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of PRKCB mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PRKCB mRNA
CTD PMID:19684285 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
JBrowse link
G Prkcd protein kinase C, delta multiple interactions EXP Cycloheximide inhibits the reaction [Buthionine Sulfoximine results in increased expression of PRKCD protein]; Cycloheximide inhibits the reaction [diethyl maleate results in increased expression of PRKCD protein] CTD PMID:11118818 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Prkce protein kinase C, epsilon multiple interactions EXP Cycloheximide inhibits the reaction [Buthionine Sulfoximine results in increased expression of PRKCE protein]; Cycloheximide inhibits the reaction [diethyl maleate results in increased expression of PRKCE protein] CTD PMID:11118818 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Prkcz protein kinase C, zeta multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PRKCZ mRNA] CTD PMID:11007951 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
JBrowse link
G Psen1 presenilin 1 multiple interactions ISO [PSEN1 protein affects the susceptibility to Ammonium Chloride] affects the reaction [Cycloheximide results in decreased expression of RBPJ protein]; [PSEN1 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the reaction [Cycloheximide results in decreased expression of RBPJ protein]; [PSEN1 protein affects the susceptibility to SB 203580] affects the reaction [Cycloheximide results in decreased expression of RBPJ protein]; Cycloheximide affects the reaction [PSEN1 protein affects the expression of RBPJ protein] CTD PMID:22302987 NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Psen2 presenilin 2 multiple interactions ISO Cycloheximide affects the reaction [PSEN2 protein affects the expression of RBPJ protein]; PSEN2 protein affects the reaction [Cycloheximide results in decreased expression of RBPJ protein] CTD PMID:22302987 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174
JBrowse link
G Psmd1 proteasome 26S subunit, non-ATPase 1 multiple interactions ISO PSMD1 protein affects the reaction [Cycloheximide results in increased degradation of MAF1 protein] CTD PMID:31645432 NCBI chr 9:86,709,714...86,785,213
Ensembl chr 9:86,709,947...86,785,211
JBrowse link
G Psme3 proteasome activator subunit 3 multiple interactions ISO PSME3 protein affects the reaction [Cycloheximide results in decreased expression of CDKN1A protein] CTD PMID:31645432 NCBI chr10:86,257,672...86,265,458 JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO Cycloheximide affects the reaction [sodium arsenite affects the expression of PTEN protein]; Cycloheximide inhibits the reaction [Lovastatin results in increased expression of PTEN protein]; Cycloheximide inhibits the reaction [Rosiglitazone results in increased expression of PTEN protein] CTD PMID:16425225 PMID:33256086 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO
EXP
Cycloheximide inhibits the reaction [Dinoprostone promotes the reaction [IL1B protein results in increased expression of PTGS2 protein]]; Cycloheximide inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; Cycloheximide inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein]; Cycloheximide inhibits the reaction [Tretinoin results in increased expression of PTGS2 protein]
Cycloheximide results in increased expression of PTGS2 mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 protein]]; Cycloheximide inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 protein]; Cycloheximide inhibits the reaction [KNG1 protein results in increased phosphorylation of PTGS2 protein]; Cycloheximide promotes the reaction [IL1B protein results in increased expression of PTGS2 mRNA]
CTD PMID:7575673 PMID:11112151 PMID:11286988 PMID:16696851 PMID:16894348 More... NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptn pleiotrophin increases expression
multiple interactions
ISO Cycloheximide results in increased expression of PTN mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PTN mRNA
CTD PMID:19684285 NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456
JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4A1 multiple interactions ISO Cycloheximide inhibits the reaction [Medroxyprogesterone Acetate inhibits the reaction [Estradiol results in increased expression of PTP4A1 mRNA]]; Cycloheximide promotes the reaction [Estradiol results in increased expression of PTP4A1 mRNA] CTD PMID:19146866 NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:33,214,208...33,221,964
JBrowse link
G Ptp4a3 protein tyrosine phosphatase 4A3 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PTP4A3 mRNA CTD PMID:19684285 NCBI chr 7:105,650,640...105,660,921
Ensembl chr 7:105,628,029...105,660,919
JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 multiple interactions EXP Cycloheximide inhibits the reaction [Isoproterenol results in increased expression of PTPN5 protein] CTD PMID:17623046 NCBI chr 1:97,620,638...97,681,186
Ensembl chr 1:97,620,642...97,679,882
JBrowse link
G Rabepk Rab9 effector protein with kelch motifs affects response to substance ISO RABEPK gene SNP affects the susceptibility to Cycloheximide CTD PMID:25622337 NCBI chr 3:18,061,299...18,083,191
Ensembl chr 3:18,061,574...18,083,191
JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of RAPGEF1 mRNA CTD PMID:19684285 NCBI chr 3:12,898,349...13,016,234
Ensembl chr 3:12,898,266...13,013,984
JBrowse link
G Rarb retinoic acid receptor, beta multiple interactions
increases expression
EXP Cycloheximide promotes the reaction [Tretinoin results in increased expression of RARB mRNA]
Cycloheximide results in increased expression of RARB mRNA
CTD PMID:19450544 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
JBrowse link
G Rarres2 retinoic acid receptor responder 2 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of RARRES2 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of RARRES2 mRNA
CTD PMID:19684285 NCBI chr 4:77,522,549...77,525,733
Ensembl chr 4:77,522,535...77,525,556
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO RB1 protein affects the reaction [palbociclib promotes the reaction [Cycloheximide results in decreased expression of RBL1 protein]] CTD PMID:20100483 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rbl1 RB transcriptional corepressor like 1 multiple interactions
decreases expression
ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of RBL1 mRNA]; palbociclib promotes the reaction [Cycloheximide results in decreased expression of RBL1 protein]; RB1 protein affects the reaction [palbociclib promotes the reaction [Cycloheximide results in decreased expression of RBL1 protein]] CTD PMID:11007951 PMID:20100483 NCBI chr 3:145,806,160...145,869,434
Ensembl chr 3:145,807,095...145,869,330
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of RBPJ protein
[PSEN1 protein affects the susceptibility to Ammonium Chloride] affects the reaction [Cycloheximide results in decreased expression of RBPJ protein]; [PSEN1 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the reaction [Cycloheximide results in decreased expression of RBPJ protein]; [PSEN1 protein affects the susceptibility to SB 203580] affects the reaction [Cycloheximide results in decreased expression of RBPJ protein]; Cycloheximide affects the reaction [PSEN1 protein affects the expression of RBPJ protein]; Cycloheximide affects the reaction [PSEN2 protein affects the expression of RBPJ protein]; Cycloheximide inhibits the reaction [Ammonium Chloride results in increased expression of RBPJ protein]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of RBPJ protein]; N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [Cycloheximide results in decreased expression of RBPJ protein]; PSEN2 protein affects the reaction [Cycloheximide results in decreased expression of RBPJ protein]
CTD PMID:22302987 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
affects localization
ISO [Cycloheximide co-treated with N(1),N(11)-diethylnorspermine] promotes the reaction [RELA protein binds to SAT1 promoter]; Cycloheximide promotes the reaction [RELA protein binds to SAT1 promoter]; Cycloheximide results in decreased expression of [NFKB1 protein binds to RELA protein]
Cycloheximide affects the localization of RELA protein
CTD PMID:16637064 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Ren renin multiple interactions ISO Cycloheximide inhibits the reaction [Dobutamine results in increased secretion of REN protein]; Cycloheximide inhibits the reaction [Terbutaline results in increased secretion of REN protein] CTD PMID:9203624 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Ret ret proto-oncogene decreases expression EXP Cycloheximide results in decreased expression of RET protein CTD PMID:17555550 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
JBrowse link
G RGD1304694 similar to CG9646-PA multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of KIAA0930 mRNA CTD PMID:19684285 NCBI chr 7:116,068,047...116,107,713
Ensembl chr 7:116,071,447...116,107,727
JBrowse link
G Rgn regucalcin multiple interactions ISO Cycloheximide inhibits the reaction [Zinc Sulfate results in increased expression of RGN mRNA] CTD PMID:18327666 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
G Rhob ras homolog family member B multiple interactions ISO Cycloheximide inhibits the reaction [cytotoxic necrotizing factor type 1 results in increased expression of RHOB protein] CTD PMID:23732113 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 multiple interactions ISO Cycloheximide promotes the reaction [FBXW7 protein binds to and results in decreased expression of RICTOR protein]
Cycloheximide inhibits the reaction [Thapsigargin affects the localization of RICTOR mRNA]
CTD PMID:25897075 PMID:29576526 NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426
JBrowse link
G Rnf4 ring finger protein 4 decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of RNF4 protein
Cycloheximide inhibits the reaction [MLN7243 affects the localization of RNF4 protein]
CTD PMID:20943951 PMID:31285264 NCBI chr14:76,401,292...76,423,270
Ensembl chr14:76,401,299...76,422,566
JBrowse link
G Rps27l ribosomal protein S27-like multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of RPS27L mRNA CTD PMID:19684285 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions EXP Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein]] CTD PMID:22689575 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 multiple interactions ISO Cycloheximide inhibits the reaction [Progesterone results in increased expression of RRM2 mRNA] CTD PMID:22403396 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO Cycloheximide inhibits the reaction [Cryptoxanthins results in increased expression of RUNX2 mRNA]; Cycloheximide inhibits the reaction [Zinc Sulfate results in increased expression of RUNX2 mRNA] CTD PMID:15962303 PMID:18327666 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G S100a4 S100 calcium-binding protein A4 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of S100A4 mRNA] CTD PMID:11007951 NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254
JBrowse link
G S100b S100 calcium binding protein B decreases expression EXP Cycloheximide results in decreased expression of S100B mRNA CTD PMID:19146868 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 multiple interactions ISO [Cycloheximide co-treated with N(1),N(11)-diethylnorspermine] promotes the reaction [RELA protein binds to SAT1 promoter]; Cycloheximide promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of SAT1 mRNA]; Cycloheximide promotes the reaction [RELA protein binds to SAT1 promoter]; NFKBIA protein affects the reaction [Cycloheximide promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of SAT1 mRNA]] CTD PMID:16637064 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO Cycloheximide inhibits the reaction [Clofibrate results in increased expression of SCD1 mRNA] CTD PMID:8790349 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Sec11c SEC11 homolog C, signal peptidase complex subunit multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] affects the expression of SEC11C mRNA CTD PMID:19684285 NCBI chr18:59,320,932...59,337,272
Ensembl chr18:59,320,884...59,337,364
JBrowse link
G Serpinb9 serpin family B member 9 multiple interactions ISO Cycloheximide promotes the reaction [moxestrol results in increased expression of SERPINB9 mRNA] CTD PMID:10681578 NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO
EXP
Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINE1 mRNA]
Cycloheximide inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; Cycloheximide promotes the reaction [FGF2 protein results in increased expression of SERPINE1 mRNA]
Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINE1 mRNA]
CTD PMID:9798919 PMID:11007951 PMID:12111005 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Serpine2 serpin family E member 2 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of SERPINE2 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SERPINE2 mRNA
CTD PMID:19684285 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
JBrowse link
G Sertad2 SERTA domain containing 2 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of SERTAD2 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SERTAD2 mRNA
CTD PMID:19684285 NCBI chr14:94,733,637...94,838,200
Ensembl chr14:94,733,579...94,838,313
JBrowse link
G Sesn2 sestrin 2 multiple interactions
decreases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of SESN2 protein]; Cycloheximide inhibits the reaction [Lipopolysaccharides results in increased expression of SESN2 protein] CTD PMID:25637945 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 multiple interactions ISO Cycloheximide inhibits the reaction [Cadmium Chloride results in increased expression of SGK1 protein] CTD PMID:25128767 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
JBrowse link
G Sirpa signal-regulatory protein alpha multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of SIRPA mRNA] CTD PMID:11007951 NCBI chr 3:116,819,730...116,858,099
Ensembl chr 3:116,819,726...116,858,098
JBrowse link
G Sirt1 sirtuin 1 multiple interactions
decreases expression
ISO Cycloheximide promotes the reaction [antimony trichloride results in decreased expression of SIRT1 protein]; pyrazolanthrone inhibits the reaction [Silicon Dioxide promotes the reaction [Cycloheximide results in decreased expression of SIRT1 protein]]; Silicon Dioxide promotes the reaction [Cycloheximide results in decreased expression of SIRT1 protein] CTD PMID:30055241 PMID:31082419 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Sla src-like adaptor multiple interactions ISO Cycloheximide inhibits the reaction [Tretinoin results in increased expression of SLA mRNA] CTD PMID:9020066 NCBI chr 7:98,534,431...98,584,810
Ensembl chr 7:98,535,368...98,584,648
JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SLC16A1 mRNA CTD PMID:19684285 NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611
JBrowse link
G Slc1a1 solute carrier family 1 member 1 multiple interactions EXP Cycloheximide inhibits the reaction [Tretinoin results in increased expression of SLC1A1 mRNA] CTD PMID:19450544 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402
JBrowse link
G Slc22a4 solute carrier family 22 member 4 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of SLC22A4 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SLC22A4 mRNA
CTD PMID:19684285 NCBI chr10:38,133,333...38,179,932 JBrowse link
G Slc25a27 solute carrier family 25, member 27 increases expression ISO Cycloheximide results in increased expression of SLC25A27 mRNA CTD PMID:20385226 NCBI chr 9:17,306,898...17,333,942
Ensembl chr 9:17,307,023...17,332,731
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SLC2A1 mRNA CTD PMID:19684285 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Slc2a5 solute carrier family 2 member 5 multiple interactions EXP Cycloheximide inhibits the reaction [Fructose promotes the reaction [SLC2A5 protein results in increased uptake of Fructose]] CTD PMID:11123204 NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106
JBrowse link
G Slc39a4 solute carrier family 39 member 4 multiple interactions ISO Cycloheximide inhibits the reaction [Zinc deficiency results in increased expression of SLC39A4 mRNA]; Cycloheximide inhibits the reaction [Zinc results in decreased expression of SLC39A4 mRNA] CTD PMID:18020946 NCBI chr 7:108,333,380...108,337,553
Ensembl chr 7:108,333,381...108,337,553
JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression ISO Cycloheximide results in increased expression of SLC3A2 mRNA CTD PMID:26621329 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
JBrowse link
G Slc5a5 solute carrier family 5 member 5 increases expression ISO Cycloheximide results in increased expression of SLC5A5 mRNA CTD PMID:17164311 NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697
JBrowse link
G Slc7a5 solute carrier family 7 member 5 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SLC7A5 mRNA CTD PMID:19684285 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
JBrowse link
G Smn1 survival of motor neuron 1, telomeric multiple interactions ISO Cycloheximide inhibits the reaction [Paraquat results in increased expression of SMN1 mRNA alternative form] CTD PMID:17064354 NCBI chr 2:31,490,018...31,501,065
Ensembl chr 2:31,490,015...31,501,060
JBrowse link
G Snw1 SNW domain containing 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SNW1 mRNA CTD PMID:19684285 NCBI chr 6:107,095,450...107,119,536
Ensembl chr 6:107,095,457...107,119,536
JBrowse link
G Socs1 suppressor of cytokine signaling 1 multiple interactions
increases expression
ISO [afimoxifene co-treated with Cycloheximide] results in increased expression of SOCS1 mRNA
Cycloheximide results in increased expression of SOCS1 mRNA
CTD PMID:16849584 PMID:23237828 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
JBrowse link
G Socs2 suppressor of cytokine signaling 2 multiple interactions
increases expression
ISO Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of SOCS2 mRNA]
Cycloheximide results in increased expression of SOCS2 mRNA
CTD PMID:15371557 PMID:23237828 NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548
JBrowse link
G Socs3 suppressor of cytokine signaling 3 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of SOCS3 mRNA
Dactinomycin inhibits the reaction [Cycloheximide results in increased expression of SOCS3 mRNA]; U 0126 inhibits the reaction [Cycloheximide results in increased expression of SOCS3 mRNA]
CTD PMID:23237828 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Socs4 suppressor of cytokine signaling 4 increases expression ISO Cycloheximide results in increased expression of SOCS4 mRNA CTD PMID:23237828 NCBI chr15:20,523,406...20,537,889
Ensembl chr15:20,523,183...20,542,494
JBrowse link
G Socs5 suppressor of cytokine signaling 5 increases expression ISO Cycloheximide results in increased expression of SOCS5 mRNA CTD PMID:23237828 NCBI chr 6:7,481,039...7,512,644
Ensembl chr 6:7,481,095...7,514,834
JBrowse link
G Socs6 suppressor of cytokine signaling 6 increases expression ISO Cycloheximide results in increased expression of SOCS6 mRNA CTD PMID:23237828 NCBI chr18:82,111,866...82,139,193
Ensembl chr18:82,111,827...82,139,219
JBrowse link
G Socs7 suppressor of cytokine signaling 7 increases expression ISO Cycloheximide results in increased expression of SOCS7 mRNA CTD PMID:23237828 NCBI chr10:82,352,159...82,388,829
Ensembl chr10:82,351,680...82,388,830
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
ISO Cycloheximide inhibits the reaction [NGF protein results in increased expression of SOD2 protein]; Cycloheximide inhibits the reaction [polysaccharide-K results in increased expression of SOD2]
Cycloheximide results in increased expression of SOD2 mRNA
Cycloheximide promotes the reaction [Paclitaxel results in increased expression of SOD2 mRNA]; Cycloheximide promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; Cycloheximide promotes the reaction [TNF protein results in increased expression of SOD2 mRNA]; Cycloheximide promotes the reaction [Vinblastine results in increased expression of SOD2 mRNA]; Cycloheximide promotes the reaction [Vincristine results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Cycloheximide results in increased expression of SOD2 mRNA]
CTD PMID:8037686 PMID:9852137 PMID:11154046 PMID:15330761 PMID:20495008 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sort1 sortilin 1 multiple interactions
increases degradation
EXP
ISO
SORT1 mutant form inhibits the reaction [Pentanoic Acids results in decreased susceptibility to [TNF protein co-treated with Cycloheximide]]; SORT1 mutant form inhibits the reaction [sodium arsenite results in decreased susceptibility to [TNF protein co-treated with Cycloheximide]]
Cycloheximide results in increased degradation of SORT1 protein mutant form
Cycloheximide promotes the reaction [Palmitic Acid results in increased degradation of SORT1 protein]; Docosahexaenoic Acids inhibits the reaction [Cycloheximide promotes the reaction [Palmitic Acid results in increased degradation of SORT1 protein]]
CTD PMID:22555848 PMID:24986865 PMID:25805502 NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354
JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SOS1 mRNA] CTD PMID:11007951 NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107
JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 multiple interactions ISO [TNF co-treated with Cycloheximide] results in increased cleavage of SPTAN1 protein; VASP mutant form promotes the reaction [[TNF co-treated with Cycloheximide] results in increased cleavage of SPTAN1 protein] CTD PMID:18182247 NCBI chr 3:13,241,164...13,306,047
Ensembl chr 3:13,241,217...13,306,046
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
decreases expression
ISO [sodium arsenite results in increased abundance of arsenite] inhibits the reaction [Cycloheximide results in decreased expression of SQSTM1 protein] CTD PMID:31781319 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase increases localization EXP Cycloheximide results in increased localization of SRC protein CTD PMID:10401681 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Srr serine racemase multiple interactions ISO
EXP
Cycloheximide inhibits the reaction [methyllycaconitine results in increased expression of SRR protein] CTD PMID:24012499 NCBI chr10:59,769,563...59,786,688
Ensembl chr10:59,769,571...59,787,011
JBrowse link
G Ssbp1 single stranded DNA binding protein 1 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of SSBP1 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SSBP1 mRNA
CTD PMID:19684285 NCBI chr 4:69,266,024...69,276,135
Ensembl chr 4:69,266,102...69,276,135
JBrowse link
G St18 ST18 C2H2C-type zinc finger transcription factor increases expression ISO Cycloheximide results in increased expression of ST18 mRNA CTD PMID:23236509 NCBI chr 5:12,582,493...12,914,221
Ensembl chr 5:12,584,110...12,671,790
JBrowse link
G St8sia1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 multiple interactions
increases expression
ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ST8SIA1 mRNA
Cycloheximide results in increased expression of ST8SIA1 mRNA
CTD PMID:19684285 NCBI chr 4:175,782,989...175,921,338
Ensembl chr 4:175,789,947...175,920,708
JBrowse link
G Stk3 serine/threonine kinase 3 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of STK3 mRNA] CTD PMID:11007951 NCBI chr 7:66,053,209...66,323,292
Ensembl chr 7:66,052,345...66,323,233
JBrowse link
G Stx2 syntaxin 2 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of STX2 mRNA] CTD PMID:11007951 NCBI chr12:27,678,744...27,714,751
Ensembl chr12:27,689,819...27,714,751
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions ISO Cycloheximide inhibits the reaction [Gallic Acid results in increased expression of SULT1A1 mRNA] CTD PMID:16308312 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Sult2b1 sulfotransferase family 2B member 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SULT2B1 mRNA] CTD PMID:11007951 NCBI chr 1:96,200,155...96,261,295
Ensembl chr 1:96,200,156...96,261,295
JBrowse link
G Supt4h1 SPT4 homolog, DSIF elongation factor subunit multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of SUPT4H1 mRNA] CTD PMID:11007951 NCBI chr10:72,539,323...72,545,582
Ensembl chr10:72,539,382...72,545,831
JBrowse link
G Synpo synaptopodin multiple interactions
increases expression
ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SYNPO mRNA
Cycloheximide results in increased expression of SYNPO mRNA
CTD PMID:19684285 NCBI chr18:54,048,299...54,106,388
Ensembl chr18:54,026,152...54,102,126
JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP Cycloheximide inhibits the reaction [KNG1 protein results in increased secretion of TAC1 protein] CTD PMID:16696851 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
JBrowse link
G Tacc1 transforming, acidic coiled-coil containing protein 1 multiple interactions
increases expression
ISO [Cycloheximide co-treated with Estradiol] results in decreased expression of TACC1 mRNA
Cycloheximide results in increased expression of TACC1 mRNA
CTD PMID:15072547 NCBI chr16:66,812,232...66,895,736
Ensembl chr16:66,812,295...66,895,733
JBrowse link
G Tardbp TAR DNA binding protein multiple interactions
decreases expression
ISO Cycloheximide results in decreased expression of and results in decreased stability of TARDBP protein mutant form; epoxomicin inhibits the reaction [Cycloheximide results in decreased expression of and results in decreased stability of TARDBP protein mutant form]; epoxomicin inhibits the reaction [Cycloheximide results in decreased expression of TARDBP protein] CTD PMID:24477737 NCBI chr 5:159,050,518...159,062,218
Ensembl chr 5:159,051,799...159,062,055
JBrowse link
G Tas2r106 taste receptor, type 2, member 106 multiple interactions ISO TAS2R105 protein affects the reaction [Cycloheximide results in increased phosphorylation of MAPK1 protein]; TAS2R105 protein affects the reaction [Cycloheximide results in increased phosphorylation of MAPK3 protein] CTD PMID:15087236 NCBI chr 4:165,313,210...165,314,133
Ensembl chr 4:165,313,210...165,314,133
JBrowse link
G Testin testin gene multiple interactions
decreases secretion
decreases expression
EXP Cycloheximide inhibits the reaction [lonidamine results in increased expression of TESTIN mRNA]; Cycloheximide inhibits the reaction [lonidamine results in increased secretion of TESTIN protein]
Cycloheximide results in decreased secretion of TESTIN protein
Cycloheximide results in decreased expression of TESTIN mRNA
CTD PMID:11090432 NCBI chr17:3,824,222...3,859,385
Ensembl chr17:3,846,899...3,859,385
JBrowse link
G Tff1 trefoil factor 1 multiple interactions
increases expression
ISO [Cycloheximide co-treated with Estradiol] results in increased expression of TFF1 mRNA; Cycloheximide inhibits the reaction [bisphenol A results in increased expression of TFF1 mRNA]
Cycloheximide results in increased expression of TFF1 mRNA
CTD PMID:15072547 PMID:20875696 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
JBrowse link
G Tgfa transforming growth factor alpha increases expression ISO Cycloheximide results in increased expression of TGFA mRNA CTD PMID:15228094 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
decreases activity
EXP
ISO
Cycloheximide inhibits the reaction [TGFB1 protein results in increased expression of BAX protein]; Cycloheximide inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; Cycloheximide inhibits the reaction [TGFB1 protein results in increased expression of TP53 protein]
Cycloheximide results in decreased activity of TGFB1 protein
Cycloheximide inhibits the reaction [TGFB1 protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]]; Cycloheximide inhibits the reaction [TGFB1 protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]]; Cycloheximide inhibits the reaction [TGFB1 protein results in decreased expression of AHR mRNA]; Cycloheximide inhibits the reaction [TGFB1 protein results in increased expression of ITGB6 mRNA]
CTD PMID:9145908 PMID:9790906 PMID:9798919 PMID:21303922 PMID:31652400 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 multiple interactions ISO Cycloheximide inhibits the reaction [tolfenamic acid results in decreased expression of TGFBR2 protein] CTD PMID:31381904 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Thbd thrombomodulin multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of THBD mRNA] CTD PMID:11007951 NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193
JBrowse link
G Thbs1 thrombospondin 1 multiple interactions ISO Cycloheximide inhibits the reaction [Testosterone results in decreased expression of THBS1 mRNA] CTD PMID:16723184 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Thy1 Thy-1 cell surface antigen multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of THY1 mRNA] CTD PMID:11007951 NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659
JBrowse link
G Tia1 TIA1 cytotoxic granule-associated RNA binding protein multiple interactions EXP Cycloheximide inhibits the reaction [sodium arsenite affects the localization of TIA1 protein]; TIA1 mutant form inhibits the reaction [Pentanoic Acids results in decreased susceptibility to [TNF protein co-treated with Cycloheximide]]; TIA1 mutant form inhibits the reaction [sodium arsenite results in decreased susceptibility to [TNF protein co-treated with Cycloheximide]] CTD PMID:19171178 PMID:22555848 NCBI chr 4:118,852,765...118,883,252
Ensembl chr 4:118,852,837...118,880,586
JBrowse link
G Timm17a translocase of inner mitochondrial membrane 17A multiple interactions
decreases expression
ISO Cycloheximide results in decreased expression of and results in increased degradation of TIMM17A protein; YME1L1 mutant form inhibits the reaction [Cycloheximide results in increased degradation of TIMM17A protein]
Cycloheximide results in decreased expression of TIMM17A protein
CTD PMID:24315374 NCBI chr13:46,731,117...46,742,604
Ensembl chr13:46,730,660...46,742,655
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 decreases response to substance EXP TIMP1 protein results in decreased susceptibility to Cycloheximide CTD PMID:15860571 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase multiple interactions
increases expression
ISO AHR protein promotes the reaction [Cycloheximide results in increased expression of TIPARP mRNA]; Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of TIPARP mRNA] CTD PMID:12147270 NCBI chr 2:149,753,682...149,780,327
Ensembl chr 2:149,753,682...149,780,327
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions
decreases expression
ISO Cycloheximide inhibits the reaction [IFNG protein results in increased expression of TJP1 protein]
Cycloheximide results in decreased expression of TJP1 protein
CTD PMID:16087364 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
JBrowse link
G Tm7sf3 transmembrane 7 superfamily member 3 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of TM7SF3 mRNA CTD PMID:19684285 NCBI chr 4:179,518,127...179,550,154
Ensembl chr 4:179,518,130...179,550,154
JBrowse link
G Tmem263 transmembrane protein 263 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of TMEM263 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of TMEM263 mRNA
CTD PMID:19684285 NCBI chr 7:18,607,077...18,628,436
Ensembl chr 7:18,610,149...18,628,534
JBrowse link
G Tnf tumor necrosis factor increases response to substance
multiple interactions
ISO
EXP
TNF protein results in increased susceptibility to Cycloheximide
[Cycloheximide co-treated with TNF protein] results in increased cleavage of PARP1 protein; [Cycloheximide co-treated with TNF] results in increased activity of CASP9 protein; [Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP3 protein; [Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP8 protein; [Cycloheximide co-treated with TNF] results in increased cleavage of BID protein; [TNF protein co-treated with Cycloheximide] results in increased expression of TNFAIP3 mRNA; [TNF protein co-treated with Cycloheximide] results in increased secretion of CXCL8 protein; Cycloheximide inhibits the reaction [CXCL8 protein affects the secretion of TNF protein]; Cycloheximide inhibits the reaction [Morphine inhibits the reaction [TNF protein results in increased expression of CNR1 mRNA]]; Cycloheximide inhibits the reaction [Morphine inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]]; Cycloheximide inhibits the reaction [SM 164 results in increased expression of TNF mRNA]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Cycloheximide inhibits the reaction [TNF protein results in increased expression of CCL2 protein]; Cycloheximide inhibits the reaction [TNF protein results in increased expression of CCL5 protein]; Cycloheximide inhibits the reaction [TNF protein results in increased expression of CXCL10 protein]; Cycloheximide inhibits the reaction [TNF protein results in increased expression of MYLK protein]; Cycloheximide inhibits the reaction [tofacitinib inhibits the reaction [TNF protein results in increased expression of CCL2 protein]]; Cycloheximide inhibits the reaction [tofacitinib inhibits the reaction [TNF protein results in increased expression of CCL5 protein]]; Cycloheximide inhibits the reaction [tofacitinib inhibits the reaction [TNF protein results in increased expression of CXCL10 protein]]; Cycloheximide inhibits the reaction [Zinc deficiency promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]]; Cycloheximide promotes the reaction [TNF protein results in increased expression of SOD2 mRNA]; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased activity of CASP9 protein]; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP3 protein]; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP8 protein]; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of BID protein]; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of PARP1 protein]; ITPK1 mutant form promotes the reaction [[Cycloheximide co-treated with TNF protein] results in increased cleavage of BID protein]; ITPK1 mutant form promotes the reaction [[Cycloheximide co-treated with TNF protein] results in increased cleavage of PARP1 protein]; ITPK1 mutant form results in increased susceptibility to [Cycloheximide co-treated with TNF protein]; TNF protein promotes the reaction [Cycloheximide results in increased expression of CCL2 mRNA]; TNF protein promotes the reaction [Cycloheximide results in increased expression of CCL5 mRNA]; TNF protein promotes the reaction [Cycloheximide results in increased expression of CXCL8 mRNA]; TNF protein promotes the reaction [Cycloheximide results in increased expression of IL6 mRNA]; TNF protein promotes the reaction [Cycloheximide results in increased expression of NFKB1 mRNA]; TNF protein promotes the reaction [Cycloheximide results in increased secretion of IL6 protein]; Ursodeoxycholic Acid analog inhibits the reaction [[TNF protein co-treated with Cycloheximide] results in increased secretion of CXCL8 protein]; Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of CCL2 mRNA]]; Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of CCL5 mRNA]]; Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of CXCL8 mRNA]]; Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of IL6 mRNA]]; Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of NFKB1 mRNA]]; Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased secretion of IL6 protein]]; Ursodeoxycholic Acid analog promotes the reaction [[TNF protein co-treated with Cycloheximide] results in increased expression of TNFAIP3 mRNA]
Cycloheximide inhibits the reaction [TNF protein results in decreased export of Potassium]; Pentanoic Acids results in decreased susceptibility to [TNF protein co-treated with Cycloheximide]; sodium arsenite results in decreased susceptibility to [TNF protein co-treated with Cycloheximide]; SORT1 mutant form inhibits the reaction [Pentanoic Acids results in decreased susceptibility to [TNF protein co-treated with Cycloheximide]]; SORT1 mutant form inhibits the reaction [sodium arsenite results in decreased susceptibility to [TNF protein co-treated with Cycloheximide]]; TIA1 mutant form inhibits the reaction [Pentanoic Acids results in decreased susceptibility to [TNF protein co-treated with Cycloheximide]]; TIA1 mutant form inhibits the reaction [sodium arsenite results in decreased susceptibility to [TNF protein co-treated with Cycloheximide]]
[TNF co-treated with Cycloheximide] results in increased cleavage of SPTAN1 protein; Cycloheximide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]; Cycloheximide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; Cycloheximide promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; VASP mutant form promotes the reaction [[TNF co-treated with Cycloheximide] results in increased cleavage of SPTAN1 protein]
CTD PMID:8037686 PMID:8071060 PMID:12185005 PMID:12812920 PMID:12925536 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 multiple interactions ISO [TNF protein co-treated with Cycloheximide] results in increased expression of TNFAIP3 mRNA; Ursodeoxycholic Acid analog promotes the reaction [[TNF protein co-treated with Cycloheximide] results in increased expression of TNFAIP3 mRNA] CTD PMID:21146893 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b multiple interactions ISO Cycloheximide inhibits the reaction [Docetaxel results in increased expression of TNFRSF10A protein]; Cycloheximide inhibits the reaction [Paclitaxel results in increased expression of TNFRSF10A protein] CTD PMID:11212279 NCBI chr15:44,839,818...44,867,582 JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of TNFRSF11B mRNA CTD PMID:19684285 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
JBrowse link
G Tnfrsf26 tumor necrosis factor receptor superfamily, member 26 multiple interactions EXP Cycloheximide inhibits the reaction [tetrachlorobenzoquinone results in increased expression of TNFRSF10B mRNA] CTD PMID:27484784 NCBI chr 1:198,802,513...198,824,049
Ensembl chr 1:198,802,971...198,823,418
JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TNFRSF8 mRNA] CTD PMID:11007951 NCBI chr 5:157,123,183...157,168,421
Ensembl chr 5:157,123,185...157,168,421
JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO [Cycloheximide co-treated with TNFSF10 protein] results in increased activity of CASP3 protein; [Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP8 protein; [Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP9 protein; [Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [sodium arsenite results in increased expression of and results in increased localization of TNFRSF10B protein]] results in increased susceptibility to [TNFSF10 protein co-treated with Cycloheximide]; BCL2 protein inhibits the reaction [[Cycloheximide co-treated with TNFSF10 protein] results in increased activity of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP8 protein]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of TNFSF10 mRNA] CTD PMID:11007951 PMID:18222423 PMID:22343715 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of TNFSF11 mRNA]
Cycloheximide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Cryptoxanthins] promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] promotes the reaction [Cryptoxanthins results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [Genistein promotes the reaction [[Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [Zinc Sulfate results in increased expression of TNFSF11 mRNA]
CTD PMID:11007951 PMID:17295206 PMID:18327666 PMID:18636177 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445
JBrowse link
G Tnnc1 troponin C1, slow skeletal and cardiac type multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TNNC1 mRNA] CTD PMID:11007951 NCBI chr16:6,400,801...6,405,419
Ensembl chr16:6,402,171...6,405,634
JBrowse link
G Tp53 tumor protein p53 increases response to substance
increases degradation
decreases expression
multiple interactions
ISO
EXP
TP53 mutant form results in increased susceptibility to Cycloheximide
Cycloheximide results in increased degradation of TP53 protein
Cycloheximide results in decreased expression of TP53 protein
Cycloheximide inhibits the reaction [Cyclosporine results in increased expression of TRP53 protein]
Cycloheximide inhibits the reaction [TGFB1 protein results in increased expression of TP53 protein]
Cycloheximide inhibits the reaction [Fluorouracil results in increased expression of TP53 protein]; Cycloheximide promotes the reaction [Chlorpyrifos results in decreased expression of TP53 protein]; leptomycin B inhibits the reaction [Cycloheximide results in increased degradation of TP53 protein]
CTD PMID:9790906 PMID:10760090 PMID:15016801 PMID:20943951 PMID:21875941 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp53i11 tumor protein p53 inducible protein 11 multiple interactions
decreases expression
ISO Cycloheximide inhibits the reaction [arsenic trioxide results in increased expression of TP53I11 mRNA]
Cycloheximide results in decreased expression of TP53I11 mRNA
CTD PMID:19333544 NCBI chr 3:79,144,824...79,160,056
Ensembl chr 3:79,144,895...79,160,050
JBrowse link
G Tp63 tumor protein p63 multiple interactions ISO Cycloheximide inhibits the reaction [trichostatin A results in increased expression of TP63 protein alternative form] CTD PMID:20043870 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
JBrowse link
G Tubgcp3 tubulin, gamma complex associated protein 3 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of TUBGCP3 mRNA] CTD PMID:11007951 NCBI chr16:76,851,859...76,912,499
Ensembl chr16:76,851,810...76,912,499
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO Cycloheximide inhibits the reaction [Acrolein results in increased expression of TXNRD1 mRNA]; Cycloheximide inhibits the reaction [sulforaphane results in increased expression of TXNRD1 mRNA] CTD PMID:12663510 PMID:15652504 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Tymp thymidine phosphorylase decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of TYMP protein
salinomycin inhibits the reaction [Cycloheximide results in decreased expression of TYMP protein]; tanespimycin inhibits the reaction [salinomycin inhibits the reaction [Cycloheximide results in decreased expression of TYMP protein]]
CTD PMID:30796972 NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874
Ensembl chr 7:120,438,770...120,443,874
JBrowse link
G Tyms thymidylate synthetase multiple interactions ISO Cycloheximide inhibits the reaction [trichostatin A results in decreased expression of TYMS mRNA] CTD PMID:17172411 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
JBrowse link
G Tyr tyrosinase multiple interactions ISO Cycloheximide inhibits the reaction [Quercetin results in increased activity of TYR protein]
[resorcinol co-treated with Cycloheximide] results in increased expression of TYR protein; SB 203580 inhibits the reaction [[resorcinol co-treated with Cycloheximide] results in increased expression of TYR protein]
CTD PMID:14717847 PMID:29621941 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 multiple interactions EXP Cycloheximide inhibits the reaction [Mevinphos results in increased expression of UCHL1 protein] CTD PMID:15545831 NCBI chr14:41,485,033...41,495,590
Ensembl chr14:41,485,031...41,495,590
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions
decreases expression
ISO [Cycloheximide co-treated with Estradiol] results in decreased expression of UGT1A1 mRNA
Cycloheximide results in decreased expression of UGT1A1 mRNA
CTD PMID:15072547 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 multiple interactions EXP Cycloheximide inhibits the reaction [Paraquat results in increased expression of UGT1A6 mRNA] CTD PMID:22846377 NCBI chr 9:88,747,229...88,808,465 JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of ULK1 protein
Antimycin A inhibits the reaction [Cycloheximide results in decreased expression of ULK1 protein]; Cycloheximide inhibits the reaction [Antimycin A results in increased expression of ULK1 protein]
CTD PMID:27629431 NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966
JBrowse link
G Vasp vasodilator-stimulated phosphoprotein multiple interactions ISO VASP mutant form promotes the reaction [[TNF co-treated with Cycloheximide] results in increased cleavage of SPTAN1 protein] CTD PMID:18182247 NCBI chr 1:78,910,009...78,925,791
Ensembl chr 1:78,910,011...78,925,061
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO Cycloheximide inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 protein] CTD PMID:12892526 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases expression
EXP
ISO
Cycloheximide promotes the reaction [Estradiol results in increased expression of VEGFA mRNA alternative form]
Cycloheximide results in increased expression of VEGFA mRNA
Cycloheximide inhibits the reaction [sodium arsenite results in increased expression of VEGFA mRNA]; Cycloheximide promotes the reaction [cobaltous chloride results in increased expression of VEGFA mRNA]; Cycloheximide promotes the reaction [nickel chloride results in increased expression of VEGFA mRNA]; Cycloheximide promotes the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]
[Cycloheximide co-treated with Norepinephrine] results in increased expression of VEGFA mRNA
CTD PMID:8344219 PMID:8537383 PMID:10788502 PMID:11641398 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vegfd vascular endothelial growth factor D multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of VEGFD mRNA] CTD PMID:11007951 NCBI chr  X:30,073,122...30,108,413
Ensembl chr  X:30,074,163...30,108,295
JBrowse link
G Virma vir like m6A methyltransferase associated affects response to substance ISO VIRMA gene SNP affects the susceptibility to Cycloheximide CTD PMID:25622337 NCBI chr 5:24,961,208...25,024,660
Ensembl chr 5:24,960,778...25,023,341
JBrowse link
G Vldlr very low density lipoprotein receptor multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of VLDLR mRNA] CTD PMID:11007951 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
JBrowse link
G Vsnl1 visinin-like 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of VSNL1 mRNA] CTD PMID:11007951 NCBI chr 6:34,038,641...34,159,479
Ensembl chr 6:34,038,642...34,159,479
JBrowse link
G Wwox WW domain-containing oxidoreductase affects response to substance ISO WWOX gene SNP affects the susceptibility to Cycloheximide CTD PMID:25622337 NCBI chr19:42,432,141...43,360,278 JBrowse link
G Xiap X-linked inhibitor of apoptosis multiple interactions ISO Cycloheximide inhibits the reaction [Thapsigargin affects the localization of XIAP mRNA] CTD PMID:29576526 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link
G Yap1 Yes1 associated transcriptional regulator multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of YAP1 mRNA CTD PMID:19684285 NCBI chr 8:5,095,705...5,166,808
Ensembl chr 8:5,095,722...5,167,010
JBrowse link
G Yme1l1 YME1-like 1 ATPase multiple interactions ISO YME1L1 mutant form inhibits the reaction [Cycloheximide results in increased degradation of TIMM17A protein] CTD PMID:24315374 NCBI chr17:85,287,607...85,326,068
Ensembl chr17:85,287,554...85,326,335
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        inhibitor 18592
          ferroptosis inhibitor 7515
            cycloheximide 460
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic group 18737
                              organic divalent group 18728
                                organodiyl group 18728
                                  carbonyl group 18675
                                    carbonyl compound 18675
                                      ketone 16923
                                        cyclic ketone 15391
                                          cycloheximide 460
paths to the root