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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cobalt atom
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Accession:CHEBI:27638 term browser browse the term
Definition:A cobalt group element atom that has atomic number 27.
Synonyms:related_synonym: 27Co;   Co;   Formula=Co;   InChI=1S/Co;   InChIKey=GUTLYIVDDKVIGB-UHFFFAOYSA-N;   Kobalt;   SMILES=[Co];   cobalt;   cobalto;   cobaltum
 alt_id: CHEBI:23335;   CHEBI:3788
 xref: CAS:7440-48-4;   KEGG:C00175;   KEGG:C19171
 xref_mesh: MESH:D003035
 xref: PDBeChem:3CO;   WebElements:Co



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cobalt atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GNRH1 gonadotropin releasing hormone 1 multiple interactions
affects binding
EXP [Cobalt binds to GNRH1 protein] which results in increased abundance of Cyclic AMP; [Cobalt binds to GNRH1 protein] which results in increased secretion of LHB protein CTD PMID:15833593 NCBI chr14:9,442,971...9,447,521
Ensembl chr14:9,442,971...9,453,035
JBrowse link
G LHB luteinizing hormone subunit beta multiple interactions EXP [Cobalt binds to GNRH1 protein] which results in increased secretion of LHB protein CTD PMID:15833593 NCBI chr 6:54,263,574...54,269,286 JBrowse link
G LTA4H leukotriene A4 hydrolase increases activity EXP Cobalt results in increased activity of LTA4H protein CTD PMID:21670530 NCBI chr 5:87,486,552...87,518,520
Ensembl chr 5:87,486,512...87,518,515
JBrowse link
cobalt dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AOC1 amine oxidase copper containing 1 affects binding EXP cobaltous chloride binds to AOC1 protein CTD PMID:16842785 NCBI chr18:6,309,583...6,321,016
Ensembl chr18:6,309,594...6,320,974
JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 increases expression EXP cobaltous chloride results in increased expression of HSP90B1 mRNA CTD PMID:17464326 NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,506...80,530,991
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression EXP cobaltous chloride results in increased expression of HSPA5 mRNA CTD PMID:17464326 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894
JBrowse link
cyanocob(III)alamin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAT catalase multiple interactions EXP [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] promotes the reaction [bisphenol A results in decreased expression of CAT protein]; [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of CAT mRNA; [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of CAT protein CTD PMID:29129240 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
JBrowse link
G DNMT1 DNA methyltransferase 1 multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of DNMT1 mRNA CTD PMID:28445388 NCBI chr 2:68,981,564...69,040,364
Ensembl chr 2:68,981,566...69,029,844
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of DNMT3A mRNA]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of DNMT3A mRNA CTD PMID:28445388 NCBI chr 3:113,501,972...113,609,148
Ensembl chr 3:113,528,926...113,603,087
JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions EXP [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of GPX1 mRNA; [bisphenol A co-treated with [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12]] results in increased expression of GPX1 mRNA CTD PMID:29129240 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
JBrowse link
G MTHFR methylenetetrahydrofolate reductase multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of MTHFR mRNA CTD PMID:28445388 NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,637...71,881,820
JBrowse link
G SI sucrase-isomaltase multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SI mRNA CTD PMID:28445388 NCBI chr13:104,296,281...104,379,558
Ensembl chr13:104,296,283...104,379,478
JBrowse link
G SLC15A1 solute carrier family 15 member 1 multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of SLC15A1 mRNA]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased methylation of SLC15A1 promoter]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SLC15A1 mRNA CTD PMID:28445388 NCBI chr11:67,652,808...67,690,457
Ensembl chr11:67,652,193...67,710,933
JBrowse link
G SLC5A1 solute carrier family 5 member 1 multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid co-treated with bisphenol A] results in increased expression of SLC5A1 mRNA; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SLC5A1 mRNA CTD PMID:28445388 NCBI chr14:48,566,400...48,704,145
Ensembl chr14:48,628,224...48,705,841
JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions EXP [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of SOD1 mRNA CTD PMID:29129240 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 1193
    chemical entity 1203
      atom 1180
        metal atom 233
          metal allergen 26
            cobalt atom 15
              cobalt molecular entity + 12
              cobalt-59 atom 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 1193
    subatomic particle 1180
      composite particle 1190
        hadron 1180
          baryon 1180
            nucleon 1180
              atomic nucleus 1180
                atom 1180
                  metal atom 233
                    transition element atom 197
                      d-block element atom 197
                        cobalt group element atom 15
                          cobalt atom 15
                            cobalt molecular entity + 12
                            cobalt-59 atom 0
paths to the root