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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:acetophenone
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Accession:CHEBI:27632 term browser browse the term
Definition:A methyl ketone that is acetone in which one of the methyl groups has been replaced by a phenyl group.
Synonyms:related_synonym: 1-Phenylethan-1-one;   1-Phenylethanone;   Acetylbenzene;   Formula=C8H8O;   InChI=1S/C8H8O/c1-7(9)8-5-3-2-4-6-8/h2-6H,1H3;   InChIKey=KWOLFJPFCHCOCG-UHFFFAOYSA-N;   Methyl phenyl ketone;   SMILES=CC(=O)c1ccccc1;   benzoyl methide
 alt_id: CHEBI:22186;   CHEBI:2403;   CHEBI:40490
 xref: CAS:98-86-2;   DrugBank:DB04619;   HMDB:HMDB0033910;   KEGG:C07113;   KNApSAcK:C00002685
 xref_mesh: MESH:C038699
 xref: PMID:10397882;   PMID:24634568;   UM-BBD_compID:c0117;   Wikipedia:Acetophenone


show annotations for term's descendants           Sort by:
acetophenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions ISO acetophenone inhibits the reaction [4-dimethylaminocinnamaldehyde binds to ALDH2 protein] CTD PMID:10609638 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Alpp alkaline phosphatase, placental increases chemical synthesis ISO ALPP protein results in increased chemical synthesis of acetophenone CTD PMID:1495895 NCBI chr 9:87,765,846...87,768,606
Ensembl chr 9:87,765,860...87,768,606 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO acetophenone binds to and results in decreased activity of ESR2 protein CTD PMID:27633901 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Or8a1b olfactory receptor family 8 subfamily A member 1B multiple interactions
increases activity		 ISO acetophenone binds to and results in increased activity of OR8A1 protein
acetophenone results in increased activity of OR8A1 protein		 CTD PMID:11943806 PMID:19052201 NCBI chr 8:37,434,903...37,435,832
Ensembl chr 8:37,434,551...37,439,746 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO acetophenone binds to and results in decreased activity of PPARG protein CTD PMID:27633901 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity ISO acetophenone results in increased activity of TRPA1 protein CTD PMID:27545873 NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19831
    role 19807
      biological role 19805
        xenobiotic 18720
          acetophenone 6
            2-methoxyacetophenone 0
            2-phenoxyacetophenone 0
            3,4,5-trimethoxyacetophenone 0
            4-acetoxy acetophenone 0
            4-hydroxy-3-methylacetophenone 0
            N-acetyl-S-phenacyl-L-cysteine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19831
    subatomic particle 19829
      composite particle 19829
        hadron 19829
          baryon 19829
            nucleon 19829
              atomic nucleus 19829
                atom 19829
                  main group element atom 19779
                    p-block element atom 19779
                      carbon group element atom 19728
                        carbon atom 19724
                          organic molecular entity 19724
                            heteroorganic entity 19477
                              organochalcogen compound 19240
                                organooxygen compound 19155
                                  carbonyl compound 18874
                                    ketone 17181
                                      methyl ketone 817
                                        acetophenones 161
                                          acetophenone 6
                                            2-methoxyacetophenone 0
                                            2-phenoxyacetophenone 0
                                            3,4,5-trimethoxyacetophenone 0
                                            4-acetoxy acetophenone 0
                                            4-hydroxy-3-methylacetophenone 0
                                            N-acetyl-S-phenacyl-L-cysteine 0
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