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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:acetophenone
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Accession:CHEBI:27632 term browser browse the term
Definition:A methyl ketone that is acetone in which one of the methyl groups has been replaced by a phenyl group.
Synonyms:related_synonym: 1-Phenylethan-1-one;   1-Phenylethanone;   Acetylbenzene;   Formula=C8H8O;   InChI=1S/C8H8O/c1-7(9)8-5-3-2-4-6-8/h2-6H,1H3;   InChIKey=KWOLFJPFCHCOCG-UHFFFAOYSA-N;   Methyl phenyl ketone;   SMILES=CC(=O)c1ccccc1;   benzoyl methide
 alt_id: CHEBI:22186;   CHEBI:2403;   CHEBI:40490
 xref: CAS:98-86-2;   DrugBank:DB04619;   HMDB:HMDB0033910;   KEGG:C07113;   KNApSAcK:C00002685
 xref_mesh: MESH:C038699
 xref: PMID:10397882;   PMID:24634568;   UM-BBD_compID:c0117;   Wikipedia:Acetophenone



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acetophenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions ISO acetophenone inhibits the reaction [4-dimethylaminocinnamaldehyde binds to ALDH2 protein] CTD PMID:10609638 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Alpp alkaline phosphatase, placental increases chemical synthesis ISO ALPP protein results in increased chemical synthesis of acetophenone CTD PMID:1495895 NCBI chr 9:87,765,846...87,768,606
Ensembl chr 9:87,765,860...87,768,606
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO acetophenone binds to and results in decreased activity of ESR2 protein CTD PMID:27633901 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO acetophenone binds to and results in decreased activity of PPARG protein CTD PMID:27633901 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity ISO acetophenone results in increased activity of TRPA1 protein CTD PMID:27545873 NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20072
    role 20024
      biological role 20023
        xenobiotic 18671
          acetophenone 5
            2-methoxyacetophenone 0
            2-phenoxyacetophenone 0
            3,4,5-trimethoxyacetophenone 0
            4-acetoxy acetophenone 0
            N-acetyl-S-phenacyl-L-cysteine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20072
    subatomic particle 20071
      composite particle 20071
        hadron 20071
          baryon 20071
            nucleon 20071
              atomic nucleus 20071
                atom 20071
                  main group element atom 19971
                    p-block element atom 19971
                      carbon group element atom 19894
                        carbon atom 19887
                          organic molecular entity 19887
                            organic group 18965
                              organic divalent group 18951
                                organodiyl group 18951
                                  carbonyl group 18903
                                    carbonyl compound 18903
                                      ketone 17111
                                        methyl ketone 769
                                          acetophenones 152
                                            acetophenone 5
                                              2-methoxyacetophenone 0
                                              2-phenoxyacetophenone 0
                                              3,4,5-trimethoxyacetophenone 0
                                              4-acetoxy acetophenone 0
                                              N-acetyl-S-phenacyl-L-cysteine 0
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