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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:acetophenone
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Accession:CHEBI:27632 term browser browse the term
Definition:A methyl ketone that is acetone in which one of the methyl groups has been replaced by a phenyl group.
Synonyms:related_synonym: 1-Phenylethan-1-one;   1-Phenylethanone;   Acetylbenzene;   Formula=C8H8O;   InChI=1S/C8H8O/c1-7(9)8-5-3-2-4-6-8/h2-6H,1H3;   InChIKey=KWOLFJPFCHCOCG-UHFFFAOYSA-N;   Methyl phenyl ketone;   SMILES=CC(=O)c1ccccc1;   benzoyl methide
 alt_id: CHEBI:22186;   CHEBI:2403;   CHEBI:40490
 xref: CAS:98-86-2;   DrugBank:DB04619;   HMDB:HMDB0033910;   KEGG:C07113;   KNApSAcK:C00002685
 xref_mesh: MESH:C038699
 xref: PMID:10397882;   PMID:24634568;   UM-BBD_compID:c0117;   Wikipedia:Acetophenone


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acetophenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions ISO acetophenone inhibits the reaction [4-dimethylaminocinnamaldehyde binds to ALDH2 protein] CTD PMID:10609638 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Alpp alkaline phosphatase, placental increases chemical synthesis ISO ALPP protein results in increased chemical synthesis of acetophenone CTD PMID:1495895 NCBI chr 9:94,189,961...94,193,054
Ensembl chr 9:94,190,067...94,192,813
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO acetophenone binds to and results in decreased activity of ESR2 protein CTD PMID:27633901 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO acetophenone binds to and results in decreased activity of PPARG protein CTD PMID:27633901 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity ISO acetophenone results in increased activity of TRPA1 protein CTD PMID:27545873 NCBI chr 5:3,783,247...3,836,485
Ensembl chr 5:3,783,247...3,836,485
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19720
      biological role 19720
        xenobiotic 18393
          acetophenone 5
            2-methoxyacetophenone 0
            2-phenoxyacetophenone 0
            3,4,5-trimethoxyacetophenone 0
            4-acetoxy acetophenone 0
            N-acetyl-S-phenacyl-L-cysteine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19580
                        carbon atom 19571
                          organic molecular entity 19571
                            organic group 18602
                              organic divalent group 18593
                                organodiyl group 18593
                                  carbonyl group 18506
                                    carbonyl compound 18506
                                      ketone 16825
                                        methyl ketone 745
                                          acetophenones 147
                                            acetophenone 5
                                              2-methoxyacetophenone 0
                                              2-phenoxyacetophenone 0
                                              3,4,5-trimethoxyacetophenone 0
                                              4-acetoxy acetophenone 0
                                              N-acetyl-S-phenacyl-L-cysteine 0
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