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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4-aminosalicylic acid
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Accession:CHEBI:27565 term browser browse the term
Definition:An aminobenzoic acid that is salicylic acid substituted by an amino group at position 4.
Synonyms:exact_synonym: 4-amino-2-hydroxybenzoic acid
 related_synonym: 2-HYDROXY-4-AMINOBENZOIC ACID;   4-Aminosalicylate;   Aminosalicylic acid;   Formula=C7H7NO3;   InChI=1S/C7H7NO3/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3,9H,8H2,(H,10,11);   InChIKey=WUBBRNOQWQTFEX-UHFFFAOYSA-N;   PAS;   Para-amino salicylic acid;   Paser;   SMILES=Nc1ccc(C(O)=O)c(O)c1;   p-aminosalicylic acid
 alt_id: CHEBI:1789;   CHEBI:20320;   CHEBI:41152
 xref: Beilstein:473071;   CAS:65-49-6;   DrugBank:DB00233;   Drug_Central:2050;   Gmelin:306153;   HMDB:HMDB0014378;   KEGG:C02518;   KEGG:D00162;   LINCS:LSM-5862
 xref_mesh: MESH:D010131
 xref: PDBeChem:BHA;   PMID:11621575;   PMID:1650428;   PMID:23118010;   PMID:24663015;   PMID:25050392;   PMID:25421465;   PMID:25605031;   PMID:25963985;   PMID:26004847;   PMID:26033719;   PMID:26277036;   PMID:26596566;   PMID:26848874;   PMID:27021327;   PMID:27491492;   PMID:27617928;   PMID:27671064;   PMID:28011126;   PMID:28223391;   PMID:28394286;   PMID:28408267;   PMID:28567674;   PMID:28651968;   PMID:28717039;   PMID:28812999;   Patent:DE50835;   Patent:US2844625;   Patent:US427564;   Reaxys:473071;   Wikipedia:Aminosalicylic_Acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:137598

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4-aminosalicylic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nat1 N-acetyltransferase 1 increases acetylation ISO NAT1 protein results in increased acetylation of Aminosalicylic Acid CTD PMID:15627487 PMID:16003948 NCBI chr16:23,970,742...23,991,573
Ensembl chr16:23,970,743...23,991,573
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G Nat2 N-acetyltransferase 2 multiple interactions ISO [Peroxynitrous Acid results in decreased activity of NAT2 protein] which results in decreased acetylation of Aminosalicylic Acid CTD PMID:19248797 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      biological role 19758
        antimicrobial agent 17329
          antifungal agent 14912
            salicylic acid 741
              4-aminosalicylic acid 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organic group 18527
                              organic divalent group 18520
                                organodiyl group 18520
                                  carbonyl group 18427
                                    carbonyl compound 18427
                                      carboxylic acid 18108
                                        aromatic carboxylic acid 10901
                                          benzoic acids 10870
                                            benzoic acid 3841
                                              hydroxybenzoic acid 3231
                                                monohydroxybenzoic acid 1266
                                                  salicylic acid 741
                                                    4-aminosalicylic acid 2
paths to the root