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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4-aminosalicylic acid
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Accession:CHEBI:27565 term browser browse the term
Definition:An aminobenzoic acid that is salicylic acid substituted by an amino group at position 4.
Synonyms:exact_synonym: 4-amino-2-hydroxybenzoic acid
 related_synonym: 2-HYDROXY-4-AMINOBENZOIC ACID;   4-Aminosalicylate;   Aminosalicylic acid;   Formula=C7H7NO3;   InChI=1S/C7H7NO3/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3,9H,8H2,(H,10,11);   InChIKey=WUBBRNOQWQTFEX-UHFFFAOYSA-N;   PAS;   Para-amino salicylic acid;   Paser;   SMILES=Nc1ccc(C(O)=O)c(O)c1;   p-aminosalicylic acid
 alt_id: CHEBI:1789;   CHEBI:20320;   CHEBI:41152
 xref: Beilstein:473071;   CAS:65-49-6;   DrugBank:DB00233;   Drug_Central:2050;   Gmelin:306153;   HMDB:HMDB0014378;   KEGG:C02518;   KEGG:D00162;   LINCS:LSM-5862
 xref_mesh: MESH:D010131
 xref: PDBeChem:BHA;   PMID:11621575;   PMID:1650428;   PMID:23118010;   PMID:24663015;   PMID:25050392;   PMID:25421465;   PMID:25605031;   PMID:25963985;   PMID:26004847;   PMID:26033719;   PMID:26277036;   PMID:26596566;   PMID:26848874;   PMID:27021327;   PMID:27491492;   PMID:27617928;   PMID:27671064;   PMID:28011126;   PMID:28223391;   PMID:28394286;   PMID:28408267;   PMID:28567674;   PMID:28651968;   PMID:28717039;   PMID:28812999;   Patent:DE50835;   Patent:US2844625;   Patent:US427564;   Reaxys:473071;   Wikipedia:Aminosalicylic_Acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:137598

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4-aminosalicylic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nat1 N-acetyltransferase 1 increases acetylation ISO NAT1 protein results in increased acetylation of Aminosalicylic Acid CTD PMID:15627487, PMID:16003948 NCBI chr16:23,970,742...23,991,573
Ensembl chr16:23,970,743...23,991,573
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G Nat2 N-acetyltransferase 2 multiple interactions ISO [Peroxynitrous Acid results in decreased activity of NAT2 protein] which results in decreased acetylation of Aminosalicylic Acid CTD PMID:19248797 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      biological role 19732
        antimicrobial agent 17309
          antifungal agent 14870
            salicylic acid 740
              4-aminosalicylic acid 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18493
                              organic divalent group 18486
                                organodiyl group 18486
                                  carbonyl group 18389
                                    carbonyl compound 18389
                                      carboxylic acid 18060
                                        aromatic carboxylic acid 10889
                                          benzoic acids 10858
                                            benzoic acid 3839
                                              hydroxybenzoic acid 3227
                                                monohydroxybenzoic acid 1264
                                                  salicylic acid 740
                                                    4-aminosalicylic acid 2
paths to the root


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