Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:arsenic atom
go back to main search page
Accession:CHEBI:27563 term browser browse the term
Definition:A pnictogen that has formula As.
Synonyms:related_synonym: 33As;   Arsen;   Arsenic;   As;   Formula=As;   InChI=1S/As;   InChIKey=RQNWIZPPADIBDY-UHFFFAOYSA-N;   SMILES=[As];   arsenico;   arsenicum
 alt_id: CHEBI:22630;   CHEBI:2845
 xref: CAS:7440-38-2;   KEGG:C06269
 xref_mesh: MESH:D001151
 xref: WebElements:As


show annotations for term's descendants           Sort by:
 
arsenous acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP3 caspase 3 increases expression EXP Arsenic Trioxide results in increased expression of CASP3 CTD PMID:13129816 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,749...45,763,773
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit increases activity
increases expression
EXP Arsenic Trioxide results in increased activity of GCLC protein
Arsenic Trioxide results in increased expression of GCLC mRNA
CTD PMID:18801422 NCBI chr 7:27,209,565...27,253,535
Ensembl chr 7:27,209,564...27,253,535
JBrowse link
G GGT1 gamma-glutamyltransferase 1 increases activity
increases expression
EXP Arsenic Trioxide results in increased activity of GGT1 protein
Arsenic Trioxide results in increased expression of GGT1 mRNA
CTD PMID:18801422 NCBI chr14:49,618,737...49,638,054 JBrowse link
G TP53 tumor protein p53 increases expression EXP Arsenic Trioxide results in increased expression of TP53 CTD PMID:13129816 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,643...52,953,819
JBrowse link
diarsenic trioxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP3 caspase 3 increases expression EXP Arsenic Trioxide results in increased expression of CASP3 CTD PMID:13129816 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,749...45,763,773
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit increases activity
increases expression
EXP Arsenic Trioxide results in increased activity of GCLC protein
Arsenic Trioxide results in increased expression of GCLC mRNA
CTD PMID:18801422 NCBI chr 7:27,209,565...27,253,535
Ensembl chr 7:27,209,564...27,253,535
JBrowse link
G GGT1 gamma-glutamyltransferase 1 increases expression
increases activity
EXP Arsenic Trioxide results in increased expression of GGT1 mRNA
Arsenic Trioxide results in increased activity of GGT1 protein
CTD PMID:18801422 NCBI chr14:49,618,737...49,638,054 JBrowse link
G TP53 tumor protein p53 increases expression EXP Arsenic Trioxide results in increased expression of TP53 CTD PMID:13129816 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,643...52,953,819
JBrowse link
phenylarsine oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUOX2 dual oxidase 2 affects folding EXP oxophenylarsine affects the folding of DUOX2 protein CTD PMID:10601291 NCBI chr 1:126,620,468...126,641,406
Ensembl chr 1:126,620,477...126,641,419
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha increases expression EXP oxophenylarsine results in increased expression of HIF1A protein CTD PMID:11514583 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,181...190,674,850
JBrowse link
G INS insulin multiple interactions EXP Dimercaprol inhibits the reaction [oxophenylarsine inhibits the reaction [INS protein results in increased uptake of 2-(methylamino)isobutyric acid]]; oxophenylarsine inhibits the reaction [INS protein results in increased transport of Glucose]; oxophenylarsine inhibits the reaction [INS protein results in increased uptake of 2-(methylamino)isobutyric acid] CTD PMID:1928324, PMID:8048502 NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841
JBrowse link
G NOS3 nitric oxide synthase 3 decreases phosphorylation
affects localization
EXP oxophenylarsine results in decreased phosphorylation of NOS3 protein
oxophenylarsine affects the localization of NOS3 protein
CTD PMID:9546377 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,156...6,228,938
JBrowse link
sodium arsenite term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 increases degradation
multiple interactions
decreases expression
EXP sodium arsenite results in increased degradation of AKT1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in increased degradation of AKT1 protein]; sodium arsenite results in decreased expression of and results in increased phosphorylation of AKT1 protein; Wortmannin inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein]
sodium arsenite results in decreased expression of AKT1 protein
CTD PMID:12760830, PMID:16239170
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression
EXP bisindolylmaleimide I inhibits the reaction [sodium arsenite results in increased expression of HIF1A mRNA]; Go 6976 inhibits the reaction [sodium arsenite results in increased expression of HIF1A mRNA]
sodium arsenite results in increased expression of HIF1A mRNA; sodium arsenite results in increased expression of HIF1A protein
CTD PMID:15089098 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,181...190,674,850
JBrowse link
G MAPK6 mitogen-activated protein kinase 6 increases expression EXP sodium arsenite results in increased expression of MAPK6 protein CTD PMID:12760830 NCBI chr 1:119,725,026...119,770,988
Ensembl chr 1:119,725,029...119,771,312
JBrowse link
G NOS3 nitric oxide synthase 3 multiple interactions
increases degradation
decreases expression
EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sodium arsenite results in increased phosphorylation of NOS3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in increased degradation of NOS3 protein]; sodium arsenite results in increased phosphorylation of and results in decreased activity of NOS3 protein; Wortmannin inhibits the reaction [sodium arsenite results in increased phosphorylation of NOS3 protein]
sodium arsenite results in decreased expression of NOS3 protein
CTD PMID:16239170 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,156...6,228,938
JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha decreases expression EXP sodium arsenite results in decreased expression of PRKACA protein CTD PMID:12760830 NCBI chr 2:65,074,876...65,095,564
Ensembl chr 2:65,074,870...65,095,553
JBrowse link
G PRKCD protein kinase C delta increases phosphorylation EXP sodium arsenite results in increased phosphorylation of PRKCD protein CTD PMID:15089098 NCBI chr13:35,290,835...35,323,245
Ensembl chr13:35,290,264...35,323,356
JBrowse link
G RPS6KA1 ribosomal protein S6 kinase A1 decreases expression EXP sodium arsenite results in decreased expression of RPS6KA1 protein CTD PMID:12760830 NCBI chr 6:83,905,124...83,947,189
Ensembl chr 6:83,905,076...83,950,984
JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions
increases activity
EXP [sodium arsenite results in increased activity of SOD1 protein] which results in increased abundance of Hydrogen Peroxide CTD PMID:12530527 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,749
JBrowse link
G TP53 tumor protein p53 increases expression EXP sodium arsenite results in increased expression of TP53 CTD PMID:13129816 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,643...52,953,819
JBrowse link
G VEGFA vascular endothelial growth factor A increases expression
multiple interactions
EXP sodium arsenite results in increased expression of VEGFA mRNA
bisindolylmaleimide I inhibits the reaction [sodium arsenite results in increased expression of VEGFA mRNA]; R 59949 promotes the reaction [sodium arsenite results in increased expression of VEGFA mRNA]; sodium arsenite results in increased expression of and results in increased secretion of VEGFA protein
CTD PMID:15089098 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,038
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 880
    chemical entity 880
      atom 865
        metalloid atom 16
          arsenic atom 15
            arsenic molecular entity + 15
Path 2
Term Annotations click to browse term
  CHEBI ontology 880
    subatomic particle 865
      composite particle 865
        hadron 865
          baryon 865
            nucleon 865
              atomic nucleus 865
                atom 865
                  main group element atom 855
                    p-block element atom 852
                      pnictogen 346
                        arsenic atom 15
                          arsenic molecular entity + 15
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.