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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:folic acid
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Accession:CHEBI:27470 term browser browse the term
Definition:An N-acyl-amino acid that is a form of the water-soluble vitamin B9. Its biologically active forms (tetrahydrofolate and others) are essential for nucleotide biosynthesis and homocysteine remethylation.
Synonyms:related_synonym: (2S)-2-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzamido)pentanedioic acid;   Acfol;   Folate;   Folicet;   Folsaeure;   Formula=C19H19N7O6;   InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1;   InChIKey=OVBPIULPVIDEAO-LBPRGKRZSA-N;   N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid;   N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid;   N-pteroyl-L-glutamic acid;   PGA;   PteGlu;   Pteroylglutamic acid;   SMILES=Nc1nc2ncc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)nc2c(=O)[nH]1;   acide folique;   acido folico;   acidum folicum;   pteroyl-L-glutamic acid;   pteroyl-L-monoglutamic acid;   pteroylmonoglutamic acid;   vitamin B11;   vitamin B9;   vitamin Bc;   vitamin Be;   vitamin M
 alt_id: CHEBI:24075;   CHEBI:42610;   CHEBI:5140;   CHEBI:569217
 xref: AGR:IND606960789;   Beilstein:100781;   CAS:59-30-3;   Chemspider:5815;   DrugBank:DB00158;   Drug_Central:1231;   FooDB:FDB014504;   HMDB:HMDB0000121;   KEGG:C00504;   KEGG:D00070;   KNApSAcK:C00001539;   LINCS:LSM-5355
 xref_mesh: MESH:D005492
 xref: MetaCyc:CPD-12826;   PDBeChem:FOL;   PMID:10138938;   PMID:10897644;   PMID:10958818;   PMID:11261364;   PMID:11451208;   PMID:11959400;   PMID:14387833;   PMID:15321809;   PMID:15523939;   PMID:15754725;   PMID:15797531;   PMID:15797685;   PMID:15831910;   PMID:15990733;   PMID:16093404;   PMID:16277678;   PMID:16380297;   PMID:16871332;   PMID:17784727;   PMID:18788725;   PMID:19121630;   PMID:19335717;   PMID:19355913;   PMID:24650098;   PMID:33624660;   PMID:33965562;   PMID:33968971;   PMID:34207319;   PMID:34219855;   PMID:7738698;   PMID:8235383;   PMID:9040515;   PMID:9420019;   PMID:9565830;   PMID:9683174;   PMID:9781393;   PMID:9808640;   PMID:9808641;   Reaxys:100781;   Wikipedia:Folic_Acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:62501

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    Path 1
    Term Annotations click to browse term
      CHEBI ontology 19765
        role 19738
          biological role 19736
            physiological role 19734
              food component 19734
                nutrient 19730
                  folic acid 9355
                    4-aminofolic acid 1
                    vitamin B complex 0
    Path 2
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      CHEBI ontology 19765
        subatomic particle 19763
          composite particle 19763
            hadron 19763
              baryon 19763
                nucleon 19763
                  atomic nucleus 19763
                    atom 19763
                      main group element atom 19712
                        p-block element atom 19712
                          carbon group element atom 19658
                            carbon atom 19654
                              organic molecular entity 19654
                                organic group 18856
                                  organic divalent group 18842
                                    organodiyl group 18842
                                      carbonyl group 18807
                                        carbonyl compound 18807
                                          carboxylic acid 18523
                                            amino acid 15508
                                              alpha-amino acid 13639
                                                L-alpha-amino acid 12570
                                                  glutamine family amino acid 10278
                                                    L-glutamic acid 10220
                                                      L-glutamic acid derivative 9374
                                                        folic acids 9374
                                                          folic acid 9355
                                                            4-aminofolic acid 1
                                                            vitamin B complex 0
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