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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:folic acid
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Accession:CHEBI:27470 term browser browse the term
Definition:An N-acyl-amino acid that is a form of the water-soluble vitamin B9. Its biologically active forms (tetrahydrofolate and others) are essential for nucleotide biosynthesis and homocysteine remethylation.
Synonyms:related_synonym: (2S)-2-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzamido)pentanedioic acid;   Acfol;   Folate;   Folicet;   Folsaeure;   Formula=C19H19N7O6;   InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1;   InChIKey=OVBPIULPVIDEAO-LBPRGKRZSA-N;   N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid;   N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid;   N-pteroyl-L-glutamic acid;   PGA;   PteGlu;   Pteroylglutamic acid;   SMILES=Nc1nc2ncc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)nc2c(=O)[nH]1;   acide folique;   acido folico;   acidum folicum;   pteroyl-L-glutamic acid;   pteroyl-L-monoglutamic acid;   pteroylmonoglutamic acid;   vitamin B11;   vitamin B9;   vitamin Bc;   vitamin Be;   vitamin M
 alt_id: CHEBI:24075;   CHEBI:42610;   CHEBI:5140;   CHEBI:569217
 xref: AGR:IND606960789;   Beilstein:100781;   CAS:59-30-3;   Chemspider:5815;   DrugBank:DB00158;   Drug_Central:1231;   FooDB:FDB014504;   HMDB:HMDB0000121;   KEGG:C00504;   KEGG:D00070;   KNApSAcK:C00001539;   LINCS:LSM-5355
 xref_mesh: MESH:D005492
 xref: MetaCyc:CPD-12826;   PDBeChem:FOL;   PMID:10138938;   PMID:10897644;   PMID:10958818;   PMID:11261364;   PMID:11451208;   PMID:11959400;   PMID:14387833;   PMID:15321809;   PMID:15523939;   PMID:15754725;   PMID:15797531;   PMID:15797685;   PMID:15831910;   PMID:15990733;   PMID:16093404;   PMID:16277678;   PMID:16380297;   PMID:16871332;   PMID:17784727;   PMID:18788725;   PMID:19121630;   PMID:19335717;   PMID:19355913;   PMID:24650098;   PMID:33624660;   PMID:33965562;   PMID:33968971;   PMID:34207319;   PMID:34219855;   PMID:7738698;   PMID:8235383;   PMID:9040515;   PMID:9420019;   PMID:9565830;   PMID:9683174;   PMID:9781393;   PMID:9808640;   PMID:9808641;   Reaxys:100781;   Wikipedia:Folic_Acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:62501

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    Path 1
    Term Annotations click to browse term
      CHEBI ontology 19795
        role 19746
          biological role 19746
            physiological role 19744
              food component 19744
                nutrient 19737
                  folic acid 9359
                    4-aminofolic acid 0
                    vitamin B complex 0
    Path 2
    Term Annotations click to browse term
      CHEBI ontology 19795
        subatomic particle 19794
          composite particle 19794
            hadron 19794
              baryon 19794
                nucleon 19794
                  atomic nucleus 19794
                    atom 19794
                      main group element atom 19693
                        p-block element atom 19693
                          carbon group element atom 19614
                            carbon atom 19604
                              organic molecular entity 19604
                                organic group 18713
                                  organic divalent group 18697
                                    organodiyl group 18697
                                      carbonyl group 18646
                                        carbonyl compound 18646
                                          carboxylic acid 18341
                                            amino acid 14869
                                              alpha-amino acid 12863
                                                L-alpha-amino acid 11582
                                                  glutamine family amino acid 10274
                                                    L-glutamic acid 10219
                                                      L-glutamic acid derivative 9377
                                                        folic acids 9377
                                                          folic acid 9359
                                                            4-aminofolic acid 0
                                                            vitamin B complex 0
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