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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:phenoxymethylpenicillin
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Accession:CHEBI:27446 term browser browse the term
Definition:A penicillin compound having a 6beta-(phenoxyacetyl)amino side-chain.
Synonyms:exact_synonym: 2,2-dimethyl-6beta-[(phenoxyacetyl)amino]penam-3alpha-carboxylic acid;   3,3-dimethyl-6beta-[(phenoxyacetyl)amino]penam-2alpha-carboxylic acid (PIN)
 related_synonym: (2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1- AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID;   (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;   6-phenoxyacetamidopenicillanic acid;   Fenospen;   Formula=C16H18N2O5S;   InChI=1S/C16H18N2O5S/c1-16(2)12(15(21)22)18-13(20)11(14(18)24-16)17-10(19)8-23-9-6-4-3-5-7-9/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22)/t11-,12+,14-/m1/s1;   InChIKey=BPLBGHOLXOTWMN-MBNYWOFBSA-N;   Oracillin;   PV;   Penicillin V;   SMILES=[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)COc1ccccc1)C(O)=O;   V-Cillin;   fenoximetilpenicilina;   penicillin phenoxymethyl;   phenoxomethylpenicillin;   phenoxymethylenepenicillinic acid;   phenoxymethylpenicilline;   phenoxymethylpenicillinum
 alt_id: CHEBI:25868;   CHEBI:44947;   CHEBI:7966
 xref: Beilstein:96259;   CAS:87-08-1;   DrugBank:DB00417;   Drug_Central:2083;   KEGG:C08126;   KEGG:D05411
 xref_mesh: MESH:D010404
 xref: PDBeChem:PNV;   PMID:10930630;   PMID:12569987;   PMID:13377278;   PMID:14687482;   PMID:16033609;   PMID:19357666;   PMID:19496253;   PMID:21148688;   PMID:22763423;   PMID:23732051;   PMID:26986755;   PMID:27731424;   PMID:8566082;   Reaxys:96259;   Wikipedia:Phenoxymethylpenicillin
 cyclic_relationship: is_conjugate_acid_of CHEBI:51355


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phenoxymethylpenicillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ces1d carboxylesterase 1D increases expression ISO Penicillin V results in increased expression of CES1 mRNA CTD PMID:22609641 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Penicillin V results in increased expression of GCLM mRNA CTD PMID:22609641 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Mir185 microRNA 185 decreases expression EXP Penicillin V results in decreased expression of MIR185 mRNA CTD PMID:22112502 NCBI chr11:86,812,702...86,812,781
Ensembl chr11:86,812,702...86,812,781
JBrowse link
G Mir296 microRNA 296 decreases expression EXP Penicillin V results in decreased expression of MIR296 mRNA CTD PMID:22112502 NCBI chr 3:172,357,490...172,357,567
Ensembl chr 3:172,357,490...172,357,567
JBrowse link
G Mir330 microRNA 330 decreases expression EXP Penicillin V results in decreased expression of MIR330 mRNA CTD PMID:22112502 NCBI chr 1:80,092,681...80,092,777
Ensembl chr 1:80,092,681...80,092,777
JBrowse link
G Mir34c microRNA 34c decreases expression EXP Penicillin V results in decreased expression of MIR34C mRNA CTD PMID:22112502 NCBI chr 8:55,492,024...55,492,100
Ensembl chr 8:55,492,024...55,492,100
JBrowse link
G Mir433 microRNA 433 decreases expression EXP Penicillin V results in decreased expression of MIR433 mRNA CTD PMID:22112502 NCBI chr 6:133,712,334...133,712,426
Ensembl chr 6:133,712,334...133,712,426
JBrowse link
G Mir484 microRNA 484 decreases expression EXP Penicillin V results in decreased expression of MIR484 mRNA CTD PMID:22112502 NCBI chr10:27,845...27,921
Ensembl chr10:27,845...27,921
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Penicillin V results in increased expression of NQO1 mRNA CTD PMID:22609641 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Pir pirin increases expression ISO Penicillin V results in increased expression of PIR mRNA CTD PMID:22609641 NCBI chr  X:31,852,322...31,968,152
Ensembl chr  X:31,852,323...31,968,152
JBrowse link
G Trim16 tripartite motif-containing 16 increases expression ISO Penicillin V results in increased expression of TRIM16 mRNA CTD PMID:22609641 NCBI chr10:49,231,660...49,254,653
Ensembl chr10:49,231,730...49,254,621
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19781
    role 19726
      biological role 19726
        aetiopathogenetic role 18980
          allergen 17260
            penicillin 262
              phenoxymethylpenicillin 11
                phenoxymethylpenicillanyl group 0
                phenoxymethylpenicilloyl group 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19781
    subatomic particle 19779
      composite particle 19779
        hadron 19779
          baryon 19779
            nucleon 19779
              atomic nucleus 19779
                atom 19779
                  main group element atom 19669
                    p-block element atom 19669
                      carbon group element atom 19588
                        carbon atom 19578
                          organic molecular entity 19578
                            organic group 18620
                              organic divalent group 18611
                                organodiyl group 18611
                                  carbonyl group 18526
                                    carbonyl compound 18526
                                      carboxylic acid 18202
                                        carboacyl group 17418
                                          univalent carboacyl group 17418
                                            carbamoyl group 17216
                                              carboxamide 17216
                                                lactam 8048
                                                  beta-lactam 793
                                                    beta-lactam antibiotic 778
                                                      penams 262
                                                        penicillanic acids 262
                                                          penicillanic acid 262
                                                            6-aminopenicillanic acid 262
                                                              penicillin 262
                                                                penicillin allergen 259
                                                                  phenoxymethylpenicillin 11
                                                                    phenoxymethylpenicillanyl group 0
                                                                    phenoxymethylpenicilloyl group 0
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