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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:beta-aminopropionitrile
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Accession:CHEBI:27413 term browser browse the term
Definition:An aminopropionitrile carrying an amino group at the beta-position.
Synonyms:exact_synonym: 3-aminopropanenitrile
 related_synonym: 2-cyanoethylamine;   3-Aminopropiononitrile;   3-aminopropionitrile;   BAPN;   Formula=C3H6N2;   H2NCH2CH2CN;   InChI=1S/C3H6N2/c4-2-1-3-5/h1-2,4H2;   InChIKey=AGSPXMVUFBBBMO-UHFFFAOYSA-N;   SMILES=NCCC#N;   aminopropionitrile;   beta-alaninenitrile;   beta-aminoethyl cyanide;   beta-cyanoethylamine
 alt_id: CHEBI:10351;   CHEBI:22831
 xref: CAS:151-18-8;   Gmelin:600476;   HMDB:HMDB0004101;   KEGG:C05670
 xref_mesh: MESH:D000629
 xref: MetaCyc:BETA-AMINOPROPIONITRILE;   PMID:22434522;   PMID:24391667;   PMID:6842692;   PMID:7544946;   Reaxys:1698848;   Wikipedia:Aminopropionitrile
 cyclic_relationship: is_conjugate_base_of CHEBI:91086


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beta-aminopropionitrile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Aminopropionitrile results in decreased expression of BCL2 protein CTD PMID:24614111 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Eln elastin multiple interactions
decreases expression		 EXP Aminopropionitrile results in increased expression of and results in increased degradation of ELN protein modified form
Aminopropionitrile results in decreased expression of ELN mRNA		 CTD PMID:1680324 NCBI chr12:27,604,983...27,648,413
Ensembl chr12:21,968,544...22,011,928 		JBrowse link
G Lox lysyl oxidase decreases activity
multiple interactions		 EXP
ISO		 Aminopropionitrile results in decreased activity of LOX protein
Aminopropionitrile inhibits the reaction [cupric chloride results in increased activity of LOX protein]		 CTD PMID:16023247 PMID:19524603 PMID:22367676 PMID:25044713 NCBI chr18:48,162,889...48,175,640
Ensembl chr18:45,967,343...46,041,477 		JBrowse link
G Mmp14 matrix metallopeptidase 14 decreases activity ISO Aminopropionitrile results in decreased activity of MMP14 protein CTD PMID:24014025 NCBI chr15:31,857,824...31,867,049
Ensembl chr15:27,887,727...27,899,864 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression		 EXP Propylthiouracil inhibits the reaction [Aminopropionitrile results in increased expression of MMP2 protein] CTD PMID:33462684 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression		 EXP Propylthiouracil inhibits the reaction [Aminopropionitrile results in increased expression of MMP9 protein] CTD PMID:33462684 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO Aminopropionitrile results in decreased expression of PCNA protein CTD PMID:24614111 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Smad2 SMAD family member 2 increases phosphorylation
multiple interactions		 EXP Aminopropionitrile results in increased phosphorylation of SMAD2 protein
Propylthiouracil inhibits the reaction [Aminopropionitrile results in increased phosphorylation of SMAD2 protein]		 CTD PMID:33462684 NCBI chr18:72,124,792...72,193,345
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19887
    role 19858
      biological role 19856
        inhibitor 18945
          collagen cross-linking inhibitor 8
            beta-aminopropionitrile 8
              gamma-glutamyl-beta-aminopropiononitrile 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19887
    subatomic particle 19885
      composite particle 19885
        hadron 19885
          baryon 19885
            nucleon 19885
              atomic nucleus 19885
                atom 19885
                  main group element atom 19824
                    p-block element atom 19824
                      carbon group element atom 19763
                        carbon atom 19760
                          organic molecular entity 19760
                            one-carbon compound 17865
                              hydrogen cyanide 4837
                                cyanides 4822
                                  nitrile 4624
                                    aliphatic nitrile 2205
                                      aminopropionitrile 8
                                        beta-aminopropionitrile 8
                                          gamma-glutamyl-beta-aminopropiononitrile 0
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