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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:streptidine
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Accession:CHEBI:27405 term browser browse the term
Definition:An amino cyclitol that is scyllo-inositol in which the hydroxy groups at positions 1 and 3 are replaced by guanidino groups.
Synonyms:exact_synonym: 1,1'-[(1R,2s,3S,4R,5r,6S)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diguanidine;   N,N'''-[(1R,2s,3S,4R,5r,6S)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diguanidine
 related_synonym: 1,1'-(2,4,5,6-Tetrahydroxy-1,3-cyclohexylene)diguanidine;   1,3-diguanidino-2,4,5,6-cyclohexanetetrol;   Formula=C8H18N6O4;   InChI=1S/C8H18N6O4/c9-7(10)13-1-3(15)2(14-8(11)12)5(17)6(18)4(1)16/h1-6,15-18H,(H4,9,10,13)(H4,11,12,14)/t1-,2+,3-,4+,5-,6-;   InChIKey=MSXMXWJPFIDEMT-FAEUDGQSSA-N;   N,N'-bis(aminoiminomethyl)streptamine;   N,N'-diamidinostreptamine;   SMILES=NC(=N)N[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](NC(N)=N)[C@@H]1O
 alt_id: CHEBI:26781;   CHEBI:9280
 xref: CAS:85-17-6;   KEGG:C00837;   MetaCyc:CPD-10148;   PMID:11642734;   PMID:15736038;   PMID:16956741;   PMID:17011831;   PMID:17609790;   PMID:6076630;   Reaxys:2816623

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streptomycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoxb9 homeo box B9 multiple interactions ISO [Penicillins co-treated with Streptomycin] results in increased expression of HOXB9 mRNA CTD PMID:31711903 NCBI chr10:84,119,772...84,124,963
Ensembl chr10:84,119,884...84,123,390 		JBrowse link
G Pax3 paired box 3 multiple interactions ISO [Penicillins co-treated with Streptomycin] results in increased expression of PAX3 mRNA CTD PMID:31711903 NCBI chr 9:84,004,004...84,101,226
Ensembl chr 9:84,005,183...84,101,172 		JBrowse link
G Tcf15 transcription factor 15 multiple interactions ISO [Penicillins co-treated with Streptomycin] results in increased expression of TCF15 mRNA CTD PMID:31711903 NCBI chr 3:147,643,250...147,649,511
Ensembl chr 3:147,643,250...147,649,504 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Streptomycin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:17699551 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Uncx UNC homeobox multiple interactions ISO [Penicillins co-treated with Streptomycin] results in increased expression of UNCX mRNA CTD PMID:31711903 NCBI chr12:17,182,158...17,186,679
Ensembl chr12:17,182,163...17,186,679 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19840
    role 19790
      biological role 19790
        biochemical role 19328
          metabolite 19309
            streptidine 5
              2-deoxystreptidine 0
              O-(1->4)-alpha-L-dihydrostreptosylstreptidine 6-phosphate 0
              streptidine 6-phosphate 0
              streptomycin + 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19840
    subatomic particle 19838
      composite particle 19838
        hadron 19838
          baryon 19838
            nucleon 19838
              atomic nucleus 19838
                atom 19838
                  main group element atom 19730
                    p-block element atom 19730
                      chalcogen 19424
                        oxygen atom 19386
                          oxygen molecular entity 19386
                            hydroxides 19111
                              organic hydroxy compound 18671
                                polyol 7818
                                  cyclitol 2453
                                    inositol 41
                                      scyllo-inositol 8
                                        streptidine 5
                                          2-deoxystreptidine 0
                                          O-(1->4)-alpha-L-dihydrostreptosylstreptidine 6-phosphate 0
                                          streptidine 6-phosphate 0
                                          streptomycin + 5
paths to the root