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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:deisopropylatrazine
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Accession:CHEBI:27399 term browser browse the term
Definition:A diamino-1,3,5-triazine that is N-ethyl-1,3,5-triazine-2,4-diamine substituted by a chloro group at position 6.
Synonyms:exact_synonym: 6-chloro-N-ethyl-1,3,5-triazine-2,4-diamine
 related_synonym: 2-amino-4-chloro-6-ethylamino-s-triazine;   6-deisopropylatrazine;   Formula=C5H8ClN5;   InChI=1S/C5H8ClN5/c1-2-8-5-10-3(6)9-4(7)11-5/h2H2,1H3,(H3,7,8,9,10,11);   InChIKey=IVENSCMCQBJAKW-UHFFFAOYSA-N;   SMILES=CCNc1nc(N)nc(Cl)n1;   amino-2-chloro-6-ethylamino-s-triazine
 alt_id: CHEBI:23597;   CHEBI:4374
 xref: Beilstein:8150;   CAS:1007-28-9;   KEGG:C06556
 xref_mesh: MESH:C027880
 xref: MetaCyc:CPD-805;   PMID:14759146;   PMID:9920461;   Reaxys:8150;   UM-BBD_compID:c0166


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deisopropylatrazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 affects binding
multiple interactions
ISO 6-deisopropylatrazine binds to ESR1 protein
6-deisopropylatrazine inhibits the reaction [Estradiol binds to and results in increased activity of ESR1 protein]
CTD PMID:8858116 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Pde4a phosphodiesterase 4A decreases activity ISO 6-deisopropylatrazine results in decreased activity of PDE4A protein CTD PMID:21251949 NCBI chr 8:22,189,533...22,234,036
Ensembl chr 8:22,189,600...22,233,748
JBrowse link
G Pde5a phosphodiesterase 5A affects activity ISO 6-deisopropylatrazine affects the activity of PDE5 protein CTD PMID:21251949 NCBI chr 2:226,899,604...227,044,916
Ensembl chr 2:226,900,619...227,041,576
JBrowse link
G Pomc proopiomelanocortin increases secretion EXP 6-deisopropylatrazine results in increased secretion of POMC protein modified form CTD PMID:19690231 PMID:19710361 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19773
    role 19723
      biological role 19723
        biochemical role 19311
          metabolite 19293
            xenobiotic metabolite 14242
              bacterial xenobiotic metabolite 3615
                deisopropylatrazine 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19771
      composite particle 19771
        hadron 19771
          baryon 19771
            nucleon 19771
              atomic nucleus 19771
                atom 19771
                  main group element atom 19665
                    main group molecular entity 19665
                      s-block molecular entity 19430
                        hydrogen molecular entity 19424
                          hydrides 18758
                            inorganic hydride 17457
                              pnictogen hydride 17432
                                nitrogen hydride 17277
                                  azane 17009
                                    ammonia 17008
                                      organic amino compound 17007
                                        polyamine 8261
                                          diamine 8188
                                            diamino-1,3,5-triazine 3823
                                              1,3,5-triazine-2,4-diamine 3803
                                                6-chloro-1,3,5-triazine-2,4-diamine 3803
                                                  deisopropylatrazine 4
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