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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:zinc ion
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Accession:CHEBI:27365 term browser browse the term
Synonyms:related_synonym: zinc ions


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zinc ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmbs hydroxymethylbilane synthase decreases activity EXP Zinc ion decreases activity of purified Hmbs protein RGD PMID:6732900 RGD:25394584 NCBI chr 8:48,667,278...48,674,673
Ensembl chr 8:48,667,275...48,674,748
JBrowse link
zinc sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions ISO Zinc Sulfate inhibits the reaction [Copper Sulfate inhibits the reaction [Chenodeoxycholic Acid results in increased expression of ABCB11 mRNA]] CTD PMID:26241054 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcc10 ATP binding cassette subfamily C member 10 increases expression ISO Zinc Sulfate results in increased expression of ABCC10 mRNA CTD PMID:12756304 NCBI chr 9:17,041,351...17,061,263
Ensembl chr 9:17,041,389...17,063,780
JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 decreases expression ISO Zinc Sulfate results in decreased expression of ABCC9 mRNA CTD PMID:12756304 NCBI chr 4:176,806,098...176,928,540
Ensembl chr 4:176,805,431...176,922,424
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 increases expression EXP Zinc Sulfate results in increased expression of ABCG1 mRNA CTD PMID:17074742 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489
JBrowse link
G Abhd5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase decreases expression ISO Zinc Sulfate results in decreased expression of ABHD5 mRNA CTD PMID:16330358 NCBI chr 8:130,973,222...131,001,448
Ensembl chr 8:130,973,201...131,001,458
JBrowse link
G Acacb acetyl-CoA carboxylase beta increases expression EXP Zinc Sulfate results in increased expression of ACACB mRNA CTD PMID:17074742 NCBI chr12:48,127,149...48,238,969
Ensembl chr12:48,127,149...48,238,887
JBrowse link
G Acads acyl-CoA dehydrogenase short chain increases expression ISO Zinc Sulfate results in increased expression of ACADS mRNA CTD PMID:15226459 NCBI chr12:47,254,503...47,263,747
Ensembl chr12:47,254,484...47,263,747
JBrowse link
G Acadsb acyl-CoA dehydrogenase, short/branched chain increases expression EXP Zinc Sulfate results in increased expression of ACADSB mRNA CTD PMID:17074742 NCBI chr 1:201,981,362...202,022,771
Ensembl chr 1:201,981,357...202,021,008
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain increases expression EXP Zinc Sulfate results in increased expression of ACADVL mRNA CTD PMID:17074742 NCBI chr10:56,619,321...56,624,468
Ensembl chr10:56,619,303...56,624,526
JBrowse link
G Ace angiotensin I converting enzyme multiple interactions ISO Zinc Sulfate inhibits the reaction [Edetic Acid results in decreased activity of ACE protein] CTD PMID:28544013 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions ISO [Cryptoxanthins co-treated with Zinc Sulfate] results in decreased expression of ACP5 mRNA; [CSF1 protein co-treated with TNFSF11 protein co-treated with Cryptoxanthins co-treated with Zinc Sulfate] results in decreased expression of ACP5 mRNA; [Zinc Sulfate co-treated with Genistein co-treated with CSF1 protein co-treated with TNFSF11 protein] results in decreased expression of ACP5 mRNA CTD PMID:17295206, PMID:18636177 NCBI chr 8:23,142,733...23,149,067
Ensembl chr 8:23,142,734...23,148,396
JBrowse link
G Actb actin, beta affects expression ISO Zinc Sulfate affects the expression of ACTB protein CTD PMID:25162517 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 decreases expression EXP Zinc Sulfate results in decreased expression of ACTC1 mRNA CTD PMID:17074742 NCBI chr 3:105,507,403...105,512,939
Ensembl chr 3:105,507,403...105,512,939
JBrowse link
G Actg1 actin, gamma 1 affects expression ISO Zinc Sulfate affects the expression of ACTG1 protein CTD PMID:25162517 NCBI chr10:109,518,429...109,521,288
Ensembl chr 3:75,643,054...75,644,954
Ensembl chr10:75,643,054...75,644,954
JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) multiple interactions ISO [Ethanol co-treated with Zinc Sulfate] results in increased activity of ADH1 protein; [Ethanol co-treated with Zinc Sulfate] results in increased expression of ADH1 protein CTD PMID:15920153 NCBI chr 2:243,550,655...243,562,243
Ensembl chr 2:243,550,627...243,687,857
JBrowse link
G Adm adrenomedullin increases expression ISO Zinc Sulfate results in increased expression of ADM mRNA CTD PMID:16330358 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Afdn afadin, adherens junction formation factor increases expression ISO Zinc Sulfate results in increased expression of AFDN mRNA CTD PMID:16330358 NCBI chr 1:53,713,873...53,861,918
Ensembl chr 1:53,715,693...53,802,658
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions ISO [Zinc Sulfate co-treated with prolinedithiocarbamate] affects the localization of AIFM1 protein; Acetylcysteine inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] affects the localization of AIFM1 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] affects the localization of AIFM1 protein] CTD PMID:18951928 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Zinc Sulfate results in increased expression of AKR1C2 mRNA CTD PMID:16330358 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation
ISO
EXP
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Zinc Sulfate results in increased phosphorylation of and results in increased activity of AKT1 protein]; IGF1R mutant form inhibits the reaction [Zinc Sulfate results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [Zinc Sulfate results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [Zinc Sulfate results in increased phosphorylation of and results in increased activity of AKT1 protein]; Zinc Sulfate results in increased phosphorylation of and results in increased activity of AKT1 protein
wortmannin inhibits the reaction [Zinc Sulfate results in increased phosphorylation of AKT1 protein]
RTKI cpd inhibits the reaction [Zinc Sulfate results in increased phosphorylation of AKT1 protein]; tyrphostin AG 1024 inhibits the reaction [Zinc Sulfate results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [Zinc Sulfate results in increased phosphorylation of AKT1 protein]
CTD PMID:15355987, PMID:16224792, PMID:16973122, PMID:19946718, PMID:20100827 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alad aminolevulinate dehydratase multiple interactions
increases activity
EXP Acetylcysteine promotes the reaction [Zinc Sulfate inhibits the reaction [sodium arsenite results in decreased activity of ALAD protein]]; indium trichloride inhibits the reaction [Zinc Sulfate results in increased activity of ALAD protein]; Zinc Sulfate inhibits the reaction [indium trichloride results in decreased activity of ALAD protein]; Zinc Sulfate inhibits the reaction [Lithium Carbonate results in decreased activity of ALAD protein]; Zinc Sulfate inhibits the reaction [sodium arsenite results in decreased activity of ALAD protein] CTD PMID:7084431, PMID:16959597, PMID:19083387 NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346
JBrowse link
G Alb albumin decreases expression EXP Zinc Sulfate results in decreased expression of ALB mRNA CTD PMID:9685221 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions ISO [Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate co-treated with Ethanol] results in increased expression of ALDH2 protein CTD PMID:20118189 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 multiple interactions ISO [Ethanol co-treated with Zinc Sulfate] results in increased activity of ALDH3A1 protein CTD PMID:15920153 NCBI chr10:47,490,168...47,499,855
Ensembl chr10:47,490,153...47,499,876
JBrowse link
G Aldob aldolase, fructose-bisphosphate B decreases expression ISO Zinc Sulfate results in decreased expression of ALDOB mRNA CTD PMID:12756304 NCBI chr 5:64,805,772...64,818,813
Ensembl chr 5:64,805,773...64,818,824
JBrowse link
G Angpt4 angiopoietin 4 increases expression ISO Zinc Sulfate results in increased expression of ANGPT4 mRNA CTD PMID:16330358 NCBI chr 3:147,421,724...147,455,670
Ensembl chr 3:147,422,095...147,455,670
JBrowse link
G Anxa2 annexin A2 decreases expression
affects expression
EXP
ISO
Zinc Sulfate results in decreased expression of ANXA2 mRNA
Zinc Sulfate affects the expression of ANXA2 protein
CTD PMID:17074742, PMID:25162517 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
JBrowse link
G Ap2b1 adaptor related protein complex 2 subunit beta 1 decreases expression ISO Zinc Sulfate results in decreased expression of AP2B1 mRNA CTD PMID:12756304 NCBI chr10:70,516,462...70,621,973
Ensembl chr10:70,520,206...70,621,977
JBrowse link
G Apbb1 amyloid beta precursor protein binding family B member 1 decreases expression ISO Zinc Sulfate results in decreased expression of APBB1 mRNA CTD PMID:12756304 NCBI chr 1:170,387,625...170,411,263
Ensembl chr 1:170,387,609...170,404,056
JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 decreases expression ISO Zinc Sulfate results in decreased expression of APC2 mRNA CTD PMID:12756304 NCBI chr 7:12,258,468...12,280,459
Ensembl chr 7:12,258,468...12,275,609
JBrowse link
G Apoe apolipoprotein E increases expression ISO Zinc Sulfate results in increased expression of APOE mRNA; Zinc Sulfate results in increased expression of APOE protein CTD PMID:1883846 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Aprt adenine phosphoribosyl transferase decreases expression ISO Zinc Sulfate results in decreased expression of APRT mRNA CTD PMID:12756304 NCBI chr19:55,387,288...55,389,256
Ensembl chr19:55,387,288...55,389,256
JBrowse link
G Aqp1 aquaporin 1 increases expression EXP Zinc Sulfate results in increased expression of AQP1 mRNA CTD PMID:17074742 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Arhgef18 Rho/Rac guanine nucleotide exchange factor 18 increases expression ISO Zinc Sulfate results in increased expression of ARHGEF18 mRNA CTD PMID:12756304 NCBI chr12:1,889,252...1,998,128
Ensembl chr12:1,889,331...1,998,127
JBrowse link
G Arhgef3 Rho guanine nucleotide exchange factor 3 decreases expression ISO Zinc Sulfate results in decreased expression of ARHGEF3 mRNA CTD PMID:12756304 NCBI chr16:2,743,714...3,026,768
Ensembl chr16:2,743,823...3,026,760
JBrowse link
G Art1 ADP-ribosyltransferase 1 decreases expression EXP Zinc Sulfate results in decreased expression of ART1 mRNA CTD PMID:17074742 NCBI chr 1:167,202,064...167,206,615
Ensembl chr 1:167,197,549...167,206,614
JBrowse link
G Art3 ADP-ribosyltransferase 3 increases expression EXP Zinc Sulfate results in increased expression of ART3 mRNA CTD PMID:17074742 NCBI chr14:17,143,037...17,225,389
Ensembl chr14:17,143,040...17,225,389
JBrowse link
G Atf2 activating transcription factor 2 increases phosphorylation ISO Zinc Sulfate results in increased phosphorylation of ATF2 protein CTD PMID:9728050 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Atp2c1 ATPase secretory pathway Ca2+ transporting 1 increases expression EXP Zinc Sulfate results in increased expression of ATP2C1 mRNA CTD PMID:17074742 NCBI chr 8:113,953,959...114,039,965
Ensembl chr 8:113,955,647...114,013,623
JBrowse link
G Atp7b ATPase copper transporting beta multiple interactions ISO [Zinc Sulfate co-treated with ATP7B gene mutant form] results in decreased activity of CAT protein; Zinc Sulfate inhibits the reaction [ATP7B gene mutant form results in decreased abundance of Copper]; Zinc Sulfate inhibits the reaction [ATP7B gene mutant form results in decreased abundance of Glutathione]; Zinc Sulfate inhibits the reaction [ATP7B gene mutant form results in decreased expression of CP protein] CTD PMID:24368744 NCBI chr16:74,865,516...74,944,935
Ensembl chr16:74,865,516...74,945,286
JBrowse link
G Bag1 BAG cochaperone 1 decreases expression ISO Zinc Sulfate results in decreased expression of BAG1 mRNA CTD PMID:15226459 NCBI chr 5:57,254,421...57,267,002
Ensembl chr 5:57,254,421...57,267,002
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Zinc Sulfate binds to azilsartan] which results in increased expression of BAX protein CTD PMID:29408668 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B increases expression ISO Zinc Sulfate results in increased expression of BAZ1B mRNA CTD PMID:16330358 NCBI chr12:24,478,882...24,536,851
Ensembl chr12:24,478,898...24,537,313
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO Zinc Sulfate results in increased expression of BBC3 mRNA CTD PMID:12756304 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bbs9 Bardet-Biedl syndrome 9 decreases expression ISO Zinc Sulfate results in decreased expression of BBS9 mRNA CTD PMID:12756304 NCBI chr 8:23,491,929...24,074,524
Ensembl chr 8:23,492,621...24,074,536
Ensembl chr 8:23,492,621...24,074,536
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
EXP
ISO
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Zinc Sulfate results in increased expression of BCL2 protein]; Metipranolol inhibits the reaction [Zinc Sulfate results in increased expression of BCL2 protein]
Zinc Sulfate inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein]
CTD PMID:16799065, PMID:20096349 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
multiple interactions
EXP
ISO
Zinc Sulfate results in increased expression of BCL2L1 mRNA
[Zinc Sulfate binds to azilsartan] which results in decreased expression of BCL2L1 protein
CTD PMID:17074742, PMID:29408668 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression ISO Zinc Sulfate results in increased expression of BDNF mRNA CTD PMID:16330358 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO [Genistein co-treated with Zinc Sulfate] results in increased expression of BGLAP mRNA; Cycloheximide inhibits the reaction [[Genistein co-treated with Zinc Sulfate] results in increased expression of BGLAP mRNA] CTD PMID:17203194 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Blk BLK proto-oncogene, Src family tyrosine kinase increases expression ISO Zinc Sulfate results in increased expression of BLK mRNA CTD PMID:15226459 NCBI chr15:46,555,552...46,593,778
Ensembl chr15:46,555,188...46,593,653
JBrowse link
G Brd1 bromodomain containing 1 increases expression ISO Zinc Sulfate results in increased expression of BRD1 mRNA CTD PMID:12756304 NCBI chr 7:129,676,119...129,724,303
Ensembl chr 7:129,676,120...129,724,303
JBrowse link
G Brd8 bromodomain containing 8 increases expression ISO Zinc Sulfate results in increased expression of BRD8 mRNA CTD PMID:12756304 NCBI chr18:27,375,645...27,423,989
Ensembl chr18:27,398,688...27,424,090
JBrowse link
G C3 complement C3 multiple interactions ISO [Zinc Sulfate co-treated with CR1L protein] results in increased expression of C3 protein CTD PMID:15086380 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Cabp4 calcium binding protein 4 increases expression ISO Zinc Sulfate results in increased expression of CABP4 mRNA CTD PMID:16330358 NCBI chr 1:219,383,452...219,388,009
Ensembl chr 1:219,383,452...219,388,009
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C increases expression EXP Zinc Sulfate results in increased expression of CACNA1C mRNA CTD PMID:17074742 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Cadm1 cell adhesion molecule 1 decreases expression ISO Zinc Sulfate results in decreased expression of CADM1 mRNA CTD PMID:16330358 NCBI chr 8:51,858,906...52,200,591
Ensembl chr 8:52,127,399...52,189,722
JBrowse link
G Cadps calcium dependent secretion activator increases expression EXP Zinc Sulfate results in increased expression of CADPS mRNA CTD PMID:17074742 NCBI chr15:15,275,489...15,690,575
Ensembl chr15:15,275,541...15,667,778
JBrowse link
G Calm1 calmodulin 1 decreases expression EXP Zinc Sulfate results in decreased expression of CALM1 mRNA CTD PMID:17074742 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
JBrowse link
G Calm3 calmodulin 3 decreases expression EXP Zinc Sulfate results in decreased expression of CALM3 mRNA CTD PMID:17074742 NCBI chr 1:78,844,520...78,851,628
Ensembl chr 1:78,843,080...78,851,719
JBrowse link
G Capn10 calpain 10 decreases expression ISO Zinc Sulfate results in decreased expression of CAPN10 mRNA CTD PMID:16330358 NCBI chr 9:100,104,000...100,112,833
Ensembl chr 9:100,104,000...100,112,832
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases cleavage
ISO
EXP
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Zinc Sulfate results in increased cleavage of CASP3 protein]; gluconic acid promotes the reaction [Zinc Sulfate inhibits the reaction [Aflatoxin B1 results in increased expression of CASP3 mRNA]]; Metipranolol inhibits the reaction [Zinc Sulfate results in increased cleavage of CASP3 protein]; Zinc Sulfate inhibits the reaction [Aflatoxin B1 results in increased expression of CASP3 mRNA]; Zinc Sulfate inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]
Zinc Sulfate results in increased expression of CASP3 mRNA
[CSF1 protein co-treated with TNFSF11 protein co-treated with Cryptoxanthins] promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]; [CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] promotes the reaction [Cryptoxanthins results in increased expression of CASP3 mRNA]; [Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 mRNA; Cryptoxanthins promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]; Cycloheximide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Cryptoxanthins] promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] promotes the reaction [Cryptoxanthins results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [Cryptoxanthins promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [Genistein promotes the reaction [[Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [Genistein promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [Zinc Sulfate promotes the reaction [Cryptoxanthins results in increased expression of CASP3 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Cryptoxanthins] promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] promotes the reaction [Cryptoxanthins results in increased expression of CASP3 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Cryptoxanthins promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Genistein promotes the reaction [[Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Genistein promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Zinc Sulfate promotes the reaction [Cryptoxanthins results in increased expression of CASP3 mRNA]]; Genistein promotes the reaction [[Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 mRNA]; Genistein promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]; Zinc Sulfate promotes the reaction [Cryptoxanthins results in increased expression of CASP3 mRNA]; Zinc Sulfate promotes the reaction [Genistein results in increased expression of CASP3 mRNA]
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Zinc Sulfate results in increased cleavage of CASP3 protein]; Metipranolol inhibits the reaction [Zinc Sulfate results in increased cleavage of CASP3 protein]; Zinc Sulfate inhibits the reaction [Carmustine results in increased activity of CASP3 protein]
CTD PMID:16799065, PMID:17295206, PMID:18636177, PMID:20046642, PMID:20096349, PMID:27017951 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [gluconic acid co-treated with Zinc Sulfate] inhibits the reaction [Aflatoxin B1 results in increased expression of CASP8 mRNA]; Zinc Sulfate inhibits the reaction [Aflatoxin B1 results in increased expression of CASP8 mRNA] CTD PMID:27017951 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions ISO [Zinc Sulfate binds to azilsartan] which results in increased expression of CASP9 protein CTD PMID:29408668 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions
decreases activity
ISO
EXP
[Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate co-treated with Ethanol] results in increased activity of CAT protein
[Zinc Sulfate co-treated with ATP7B gene mutant form] results in decreased activity of CAT protein; Zinc Sulfate inhibits the reaction [Disulfiram results in decreased expression of CAT mRNA]
Zinc Sulfate results in decreased activity of CAT protein
Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of CAT protein]; Zinc Sulfate inhibits the reaction [Aluminum Chloride results in decreased activity of CAT protein]; Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of CAT protein]
CTD PMID:20118189, PMID:20553223, PMID:22422511, PMID:24368744, PMID:32712770 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccdc130 coiled-coil domain containing 130 increases expression ISO Zinc Sulfate results in increased expression of CCDC130 mRNA CTD PMID:12756304 NCBI chr19:25,367,552...25,378,993
Ensembl chr19:25,367,543...25,378,974
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO [Zinc Sulfate co-treated with Disulfiram] inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein] CTD PMID:32712770 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP
ISO
Zinc Sulfate results in decreased expression of CCND1 mRNA CTD PMID:12756304, PMID:17074742 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 decreases expression EXP Zinc Sulfate results in decreased expression of CCND2 mRNA CTD PMID:17074742 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression ISO Zinc Sulfate results in increased expression of CCR2 mRNA CTD PMID:12756304, PMID:32712770
G Cct4 chaperonin containing TCP1 subunit 4 affects expression ISO Zinc Sulfate affects the expression of CCT4 protein CTD PMID:25162517 NCBI chr14:107,767,392...107,780,270
Ensembl chr14:107,767,392...107,780,270
JBrowse link
G Cd163 CD163 molecule multiple interactions ISO [Zinc Sulfate co-treated with Disulfiram] results in decreased expression of CD163 mRNA CTD PMID:32712770 NCBI chr 4:156,752,063...156,785,467
Ensembl chr 4:156,752,082...156,785,467
JBrowse link
G Cd209 CD209 molecule increases expression ISO Zinc Sulfate results in increased expression of CD209 mRNA CTD PMID:32712770 NCBI chr12:2,406,879...2,413,324
Ensembl chr12:2,406,879...2,413,324
JBrowse link
G Cd22 CD22 molecule increases expression ISO Zinc Sulfate results in increased expression of CD22 mRNA CTD PMID:15226459 NCBI chr 1:89,313,475...89,329,902
Ensembl chr 1:89,314,558...89,329,418
JBrowse link
G Cd36 CD36 molecule increases expression
multiple interactions
EXP
ISO
Zinc Sulfate results in increased expression of CD36 mRNA
[Zinc Sulfate co-treated with Disulfiram] results in decreased expression of CD36 mRNA
CTD PMID:17074742, PMID:32712770 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd8b CD8b molecule increases expression ISO Zinc Sulfate results in increased expression of CD8B1 mRNA CTD PMID:16330358 NCBI chr 4:99,185,960...99,201,887
Ensembl chr 4:99,185,885...99,202,023
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP
ISO
Zinc Sulfate results in increased expression of CDKN1A mRNA
Zinc Sulfate results in increased expression of CDKN1A protein
CTD PMID:15001399, PMID:17074742 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression EXP Zinc Sulfate results in increased expression of CEBPB mRNA CTD PMID:17074742 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression EXP
ISO
Zinc Sulfate results in increased expression of CEBPD mRNA CTD PMID:12756304, PMID:17074742 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 decreases expression ISO Zinc Sulfate results in decreased expression of CHRM3 mRNA CTD PMID:16330358 NCBI chr17:63,990,599...64,463,222
Ensembl chr17:63,990,599...63,994,169
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO Zinc Sulfate inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein] CTD PMID:10820281 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Cib3 calcium and integrin binding family member 3 decreases expression ISO Zinc Sulfate results in decreased expression of CIB3 mRNA CTD PMID:16330358 NCBI chr16:19,323,516...19,332,830
Ensembl chr16:19,323,516...19,332,830
JBrowse link
G Clcn7 chloride voltage-gated channel 7 increases expression ISO Zinc Sulfate results in increased expression of CLCN7 mRNA CTD PMID:12756304 NCBI chr10:14,492,844...14,518,167
Ensembl chr10:14,492,844...14,516,894
JBrowse link
G Clcnkb chloride voltage-gated channel Kb decreases expression ISO Zinc Sulfate results in decreased expression of CLCNKB mRNA CTD PMID:12756304 NCBI chr 5:159,950,384...159,973,576
Ensembl chr 5:159,950,392...159,962,676
JBrowse link
G Cnbp CCHC-type zinc finger, nucleic acid binding protein increases expression ISO Zinc Sulfate results in increased expression of CNBP mRNA CTD PMID:15226459 NCBI chr 4:119,747,890...119,756,787
Ensembl chr 4:119,747,911...119,756,765
JBrowse link
G Cnn3 calponin 3 decreases expression EXP Zinc Sulfate results in decreased expression of CNN3 mRNA CTD PMID:17074742 NCBI chr 2:225,005,069...225,036,179
Ensembl chr 2:225,005,019...225,036,188
JBrowse link
G Cntf ciliary neurotrophic factor multiple interactions ISO Zinc Sulfate inhibits the reaction [CNTF protein results in increased phosphorylation of STAT1 protein]; Zinc Sulfate inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein] CTD PMID:16896058 NCBI chr 1:229,599,009...229,601,032
Ensembl chr 1:229,599,009...229,601,032
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO [Genistein co-treated with Zinc Sulfate] results in increased expression of COL1A1 mRNA; Cycloheximide inhibits the reaction [[Genistein co-treated with Zinc Sulfate] results in increased expression of COL1A1 mRNA] CTD PMID:17203194 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Commd10 COMM domain containing 10 decreases expression ISO Zinc Sulfate results in decreased expression of COMMD10 mRNA CTD PMID:16330358 NCBI chr18:41,022,487...41,158,374
Ensembl chr18:41,022,552...41,154,932
JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 decreases expression EXP Zinc Sulfate results in decreased expression of COX17 mRNA CTD PMID:17074742 NCBI chr11:64,962,663...64,968,437
Ensembl chr11:64,962,666...64,968,437
JBrowse link
G Cox8a cytochrome c oxidase subunit 8A decreases expression EXP Zinc Sulfate results in decreased expression of COX8A mRNA CTD PMID:17074742 NCBI chr 1:222,466,575...222,468,896
Ensembl chr 1:222,466,575...222,468,896
JBrowse link
G Cp ceruloplasmin multiple interactions ISO Zinc Sulfate inhibits the reaction [ATP7B gene mutant form results in decreased expression of CP protein] CTD PMID:24368744 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression EXP Zinc Sulfate results in increased expression of CPT1A mRNA CTD PMID:17074742 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Cr1l complement C3b/C4b receptor 1 like multiple interactions
increases expression
ISO [Zinc Sulfate co-treated with CR1L protein] results in increased expression of C3 protein
Zinc Sulfate results in increased expression of CR1L protein
CTD PMID:15086380 NCBI chr13:113,824,886...113,872,097
Ensembl chr13:113,824,892...113,872,097
JBrowse link
G Creb1 cAMP responsive element binding protein 1 affects expression
multiple interactions
increases phosphorylation
ISO Zinc Sulfate affects the expression of CREB1 mRNA
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Zinc Sulfate results in increased phosphorylation of CREB1 protein]
CTD PMID:20385217, PMID:21333516 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crlf3 cytokine receptor-like factor 3 decreases expression ISO Zinc Sulfate results in decreased expression of CRLF3 mRNA CTD PMID:12756304 NCBI chr10:67,383,664...67,401,836
Ensembl chr10:67,383,900...67,401,836
JBrowse link
G Cs citrate synthase increases expression EXP Zinc Sulfate results in increased expression of CS mRNA CTD PMID:17074742 NCBI chr 7:2,752,680...2,778,963
Ensembl chr 7:2,752,680...2,778,963
JBrowse link
G Csf1 colony stimulating factor 1 multiple interactions ISO [CSF1 protein co-treated with TNFSF11 protein co-treated with Cryptoxanthins co-treated with Zinc Sulfate] results in decreased expression of ACP5 mRNA; [CSF1 protein co-treated with TNFSF11 protein co-treated with Cryptoxanthins] promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]; [CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] promotes the reaction [Cryptoxanthins results in increased expression of CASP3 mRNA]; [CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] results in decreased expression of CTSK mRNA; [CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] results in decreased expression of NFATC1 mRNA; [Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in decreased expression of CTSK mRNA; [Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in decreased expression of NFATC1 mRNA; [Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 mRNA; [Zinc Sulfate co-treated with Genistein co-treated with CSF1 protein co-treated with TNFSF11 protein] results in decreased expression of ACP5 mRNA; Cryptoxanthins promotes the reaction [[Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in decreased expression of CTSK mRNA]; Cryptoxanthins promotes the reaction [[Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in decreased expression of NFATC1 mRNA]; Cycloheximide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Cryptoxanthins] promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] promotes the reaction [Cryptoxanthins results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [Genistein promotes the reaction [[Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Cryptoxanthins] promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] promotes the reaction [Cryptoxanthins results in increased expression of CASP3 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Genistein promotes the reaction [[Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 mRNA]]; Genistein promotes the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] results in decreased expression of CTSK mRNA]; Genistein promotes the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] results in decreased expression of NFATC1 mRNA]; Genistein promotes the reaction [[Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 mRNA]; Zinc Sulfate promotes the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Genistein] results in decreased expression of CTSK mRNA] CTD PMID:17295206, PMID:18636177 NCBI chr 2:210,522,370...210,550,546
Ensembl chr 2:210,522,375...210,550,560
JBrowse link
G Ctsk cathepsin K multiple interactions
decreases expression
ISO [CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] results in decreased expression of CTSK mRNA; [Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in decreased expression of CTSK mRNA; Cryptoxanthins promotes the reaction [[Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in decreased expression of CTSK mRNA]; Cryptoxanthins promotes the reaction [Zinc Sulfate results in decreased expression of CTSK mRNA]; Genistein promotes the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] results in decreased expression of CTSK mRNA]; Zinc Sulfate promotes the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Genistein] results in decreased expression of CTSK mRNA]; Zinc Sulfate promotes the reaction [Genistein results in decreased expression of CTSK mRNA] CTD PMID:17295206, PMID:18636177 NCBI chr 2:196,655,469...196,666,447
Ensembl chr 2:196,655,469...196,666,446
JBrowse link
G Ctsl cathepsin L increases expression EXP Zinc Sulfate results in increased expression of CTSL mRNA CTD PMID:17074742 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 decreases expression
increases expression
ISO
EXP
Zinc Sulfate results in decreased expression of CXCL2 mRNA
Zinc Sulfate results in increased expression of CXCL2 mRNA
CTD PMID:11708899, PMID:19013360 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases expression
ISO
EXP
[Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate] inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]; Zinc Sulfate inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein]; Zinc Sulfate inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]
Zinc Sulfate results in increased expression of CYP2E1 mRNA
Paraquat promotes the reaction [Zinc Sulfate results in increased expression of CYP2E1 mRNA]; Zinc Sulfate promotes the reaction [Paraquat results in increased expression of CYP2E1 mRNA]
CYP2E1 results in increased susceptibility to [Arachidonic Acid co-treated with Zinc Sulfate]; Zinc Sulfate inhibits the reaction [CYP2E1 results in increased susceptibility to Arachidonic Acid]; Zinc Sulfate inhibits the reaction [CYP2E1 results in increased susceptibility to Buthionine Sulfoximine]
CTD PMID:12566070, PMID:15920153, PMID:20118189, PMID:20553223 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 increases expression EXP Zinc Sulfate results in increased expression of CYP4B1 mRNA CTD PMID:17074742 NCBI chr 5:134,508,728...134,526,103
Ensembl chr 5:134,508,730...134,526,089
JBrowse link
G Dcaf8 DDB1 and CUL4 associated factor 8 decreases expression ISO Zinc Sulfate results in decreased expression of DCAF8 mRNA CTD PMID:16330358 NCBI chr13:90,532,153...90,587,542
Ensembl chr13:90,532,326...90,591,796
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression EXP Zinc Sulfate results in increased expression of DDIT4 mRNA CTD PMID:17074742 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Ddx23 DEAD-box helicase 23 increases expression ISO Zinc Sulfate results in increased expression of DDX23 mRNA CTD PMID:12756304 NCBI chr 7:140,325,453...140,342,730
Ensembl chr 7:140,325,431...140,342,727
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 increases expression EXP Zinc Sulfate results in increased expression of DGAT1 mRNA CTD PMID:17074742 NCBI chr 7:117,566,363...117,576,735
Ensembl chr 7:117,566,368...117,576,737
JBrowse link
G Dhx58 DEXH-box helicase 58 decreases expression ISO Zinc Sulfate results in decreased expression of DHX58 mRNA CTD PMID:12756304 NCBI chr10:88,599,722...88,611,562
Ensembl chr10:88,599,680...88,611,105
JBrowse link
G Dicer1 dicer 1 ribonuclease III increases expression ISO Zinc Sulfate results in increased expression of DICER1 mRNA CTD PMID:12756304 NCBI chr 6:128,388,084...128,453,234
Ensembl chr 6:128,388,053...128,434,183
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions EXP Zinc Sulfate inhibits the reaction [SCH 23390 binds to DRD1 protein] CTD PMID:9109525 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions EXP Zinc Sulfate inhibits the reaction [3-N-methylspiperone binds to DRD2 protein] CTD PMID:9109525 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Dstn destrin, actin depolymerizing factor decreases expression ISO Zinc Sulfate results in decreased expression of DSTN mRNA CTD PMID:12756304 NCBI chr 3:138,024,508...138,051,304
Ensembl chr 3:138,024,508...138,051,298
JBrowse link
G Dtx3 deltex E3 ubiquitin ligase 3 increases expression ISO Zinc Sulfate results in increased expression of DTX3 mRNA CTD PMID:16330358 NCBI chr 7:70,476,737...70,482,852
Ensembl chr 7:70,476,729...70,481,796
JBrowse link
G Dusp5 dual specificity phosphatase 5 decreases expression EXP Zinc Sulfate results in decreased expression of DUSP5 mRNA CTD PMID:17074742 NCBI chr 1:274,245,184...274,258,595
Ensembl chr 1:274,245,184...274,258,595
JBrowse link
G Dync1h1 dynein cytoplasmic 1 heavy chain 1 decreases expression ISO Zinc Sulfate results in decreased expression of DYNC1H1 mRNA CTD PMID:15226459 NCBI chr 6:134,958,854...135,085,769
Ensembl chr 6:134,958,854...135,085,769
JBrowse link
G Dync1li2 dynein, cytoplasmic 1 light intermediate chain 2 increases expression ISO Zinc Sulfate results in increased expression of DYNC1LI2 mRNA CTD PMID:12756304 NCBI chr19:740,007...762,897
Ensembl chr19:740,028...762,897
JBrowse link
G Eda ectodysplasin-A decreases expression ISO Zinc Sulfate results in decreased expression of EDA mRNA CTD PMID:12756304 NCBI chr  X:69,730,123...70,222,693
Ensembl chr  X:69,730,242...70,220,329
JBrowse link
G Ednrb endothelin receptor type B decreases expression EXP Zinc Sulfate results in decreased expression of EDNRB mRNA CTD PMID:17074742 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 affects expression ISO Zinc Sulfate affects the expression of EEF1A1 protein CTD PMID:25162517 NCBI chr 8:85,838,594...85,841,816
Ensembl chr 8:85,838,869...85,840,818
JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase increases expression EXP Zinc Sulfate results in increased expression of EEF2K mRNA CTD PMID:17074742 NCBI chr 1:190,780,211...190,839,926
Ensembl chr 1:190,780,236...190,842,324
JBrowse link
G Efna1 ephrin A1 increases expression ISO Zinc Sulfate results in increased expression of EFNA1 mRNA CTD PMID:16330358 NCBI chr 2:188,588,808...188,596,156
Ensembl chr 2:188,588,796...188,596,222
JBrowse link
G Egf epidermal growth factor multiple interactions EXP [Zinc Sulfate co-treated with EGF protein] results in increased expression of MT1A mRNA CTD PMID:7705776 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfl7 EGF-like-domain, multiple 7 decreases expression ISO Zinc Sulfate results in decreased expression of EGFL7 mRNA CTD PMID:12756304 NCBI chr 3:4,034,759...4,044,280
Ensembl chr 3:4,034,921...4,043,936
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases phosphorylation
ISO
EXP
4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [Zinc Sulfate results in increased phosphorylation of EGFR protein]; Zinc Sulfate results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:10564177, PMID:11943669, PMID:16410015, PMID:19946718 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 increases expression ISO Zinc Sulfate results in increased expression of EGLN1 mRNA CTD PMID:16330358 NCBI chr19:57,660,194...57,701,158
Ensembl chr19:57,662,278...57,699,113
JBrowse link
G Ehd1 EH-domain containing 1 increases expression ISO Zinc Sulfate results in increased expression of EHD1 mRNA CTD PMID:12756304 NCBI chr 1:221,644,867...221,667,242
Ensembl chr 1:221,644,867...221,667,239
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 affects expression ISO Zinc Sulfate affects the expression of EIF4A2 protein CTD PMID:25162517 NCBI chr11:81,373,047...81,379,680
Ensembl chr11:81,373,048...81,379,871
JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions
increases activity
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Zinc Sulfate results in increased activity of ELK1 protein] CTD PMID:10564177 NCBI chr  X:1,287,875...1,304,822
Ensembl chr  X:1,297,099...1,304,822
JBrowse link
G Emid1 EMI domain containing 1 increases expression ISO Zinc Sulfate results in increased expression of EMID1 mRNA CTD PMID:15226459 NCBI chr14:85,357,221...85,400,396
Ensembl chr14:85,357,222...85,398,532
JBrowse link
G Eno3 enolase 3 affects expression ISO Zinc Sulfate affects the expression of ENO3 protein CTD PMID:25162517 NCBI chr10:57,278,271...57,283,661
Ensembl chr10:57,278,307...57,283,653
JBrowse link
G Epha7 Eph receptor A7 increases expression ISO Zinc Sulfate results in increased expression of EPHA7 mRNA CTD PMID:16330358 NCBI chr 5:43,602,744...43,761,198
Ensembl chr 5:43,603,043...43,757,549
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP Zinc Sulfate results in increased expression of EPHX1 mRNA CTD PMID:17074742 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit increases expression ISO Zinc Sulfate results in increased expression of ERCC1 mRNA CTD PMID:15226459 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Ergic3 ERGIC and golgi 3 decreases expression ISO Zinc Sulfate results in decreased expression of ERGIC3 mRNA CTD PMID:16330358 NCBI chr 3:151,553,567...151,563,318
Ensembl chr 3:151,553,578...151,563,364
JBrowse link
G Esd esterase D decreases expression ISO Zinc Sulfate results in decreased expression of ESD mRNA CTD PMID:12756304 NCBI chr15:56,756,848...56,776,348
Ensembl chr15:56,756,661...56,776,348
JBrowse link
G Exosc7 exosome component 7 decreases expression ISO Zinc Sulfate results in decreased expression of EXOSC7 mRNA CTD PMID:12756304 NCBI chr 8:132,204,628...132,229,968
Ensembl chr 8:132,204,604...132,229,969
JBrowse link
G Fabp5 fatty acid binding protein 5 decreases expression ISO Zinc Sulfate results in decreased expression of FABP5 mRNA CTD PMID:15226459 NCBI chr 2:93,981,662...93,985,322
Ensembl chr 2:93,981,656...93,985,378
JBrowse link
G Fads1 fatty acid desaturase 1 decreases expression ISO Zinc Sulfate results in decreased expression of FADS1 mRNA CTD PMID:15226459 NCBI chr 1:226,234,034...226,249,118
Ensembl chr 1:226,234,074...226,249,138
JBrowse link
G Fam13a family with sequence similarity 13, member A decreases expression ISO Zinc Sulfate results in decreased expression of FAM13A mRNA CTD PMID:12756304 NCBI chr 4:89,183,180...89,281,282
Ensembl chr 4:89,183,768...89,281,222
JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia multiple interactions ISO Zinc Sulfate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein affects the localization of RELA protein]] CTD PMID:16818790 NCBI chr13:91,727,253...91,737,106
Ensembl chr13:91,730,925...91,737,053
JBrowse link
G Fez1 fasciculation and elongation protein zeta 1 decreases expression ISO Zinc Sulfate results in decreased expression of FEZ1 mRNA CTD PMID:12756304 NCBI chr 8:39,305,128...39,350,270
Ensembl chr 8:39,305,128...39,350,270
JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression EXP Zinc Sulfate results in increased expression of FGF1 mRNA CTD PMID:17074742 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 increases expression EXP Zinc Sulfate results in increased expression of FLT1 mRNA CTD PMID:17074742 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO Zinc Sulfate results in increased expression of FOS mRNA CTD PMID:10362023 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxn4 forkhead box N4 increases expression ISO Zinc Sulfate results in increased expression of FOXN4 mRNA CTD PMID:16330358 NCBI chr12:48,101,012...48,121,281
Ensembl chr12:48,101,673...48,121,270
JBrowse link
G Foxo1 forkhead box O1 multiple interactions
affects localization
increases phosphorylation
ISO wortmannin inhibits the reaction [Zinc Sulfate affects the localization of FOXO1 protein]; wortmannin inhibits the reaction [Zinc Sulfate results in increased phosphorylation of FOXO1 protein] CTD PMID:16973122 NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016
JBrowse link
G Foxo3 forkhead box O3 increases expression ISO Zinc Sulfate results in increased expression of FOXO3 mRNA CTD PMID:12756304 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Foxo4 forkhead box O4 multiple interactions
increases phosphorylation
ISO wortmannin inhibits the reaction [Zinc Sulfate results in increased phosphorylation of FOXO4 protein] CTD PMID:16973122 NCBI chr  X:71,155,284...71,162,158
Ensembl chr  X:71,155,601...71,162,158
JBrowse link
G Fscn1 fascin actin-bundling protein 1 affects expression ISO Zinc Sulfate affects the expression of FSCN1 protein CTD PMID:25162517 NCBI chr12:13,655,459...13,668,595
Ensembl chr12:13,656,554...13,668,515
JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 increases expression ISO Zinc Sulfate results in increased expression of FZR1 mRNA CTD PMID:12756304 NCBI chr 7:11,201,690...11,213,614
Ensembl chr 7:11,201,690...11,213,613
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions
increases expression
ISO Zinc Sulfate promotes the reaction [Nitroprusside results in increased expression of G6PD mRNA]
Zinc Sulfate results in increased expression of G6PD mRNA
CTD PMID:17018880 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases expression ISO Zinc Sulfate results in decreased expression of GADD45A mRNA CTD PMID:15226459 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gata4 GATA binding protein 4 decreases expression EXP Zinc Sulfate results in decreased expression of GATA4 mRNA CTD PMID:17074742 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965
JBrowse link
G Gata6 GATA binding protein 6 increases expression EXP Zinc Sulfate results in increased expression of GATA6 mRNA CTD PMID:17074742 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338
JBrowse link
G Gcnt1 glucosaminyl (N-acetyl) transferase 1 increases expression EXP Zinc Sulfate results in increased expression of GCNT1 mRNA CTD PMID:17074742 NCBI chr 1:236,547,729...236,585,037
Ensembl chr 1:236,580,034...236,585,035
JBrowse link
G Gdnf glial cell derived neurotrophic factor decreases expression ISO Zinc Sulfate results in decreased expression of GDNF mRNA CTD PMID:12756304 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Gh1 growth hormone 1 multiple interactions EXP Zinc Sulfate affects the reaction [GH protein results in increased expression of IGF1 mRNA] CTD PMID:9685221 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Ghr growth hormone receptor decreases expression EXP Zinc Sulfate results in decreased expression of GHR mRNA CTD PMID:9685221 NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression EXP Zinc Sulfate results in decreased expression of GJA1 mRNA CTD PMID:17074742 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Glul glutamate-ammonia ligase increases expression EXP Zinc Sulfate results in increased expression of GLUL mRNA CTD PMID:17074742 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Gnas GNAS complex locus decreases activity EXP Zinc Sulfate results in decreased activity of GNAS protein CTD PMID:15546818 NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483
Ensembl chr 3:172,374,957...172,428,483
JBrowse link
G Gng11 G protein subunit gamma 11 decreases expression ISO Zinc Sulfate results in decreased expression of GNG11 mRNA CTD PMID:12756304 NCBI chr 4:28,989,170...28,994,610
Ensembl chr 4:28,989,115...28,993,621
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO Zinc Sulfate inhibits the reaction [Carbon Tetrachloride results in increased expression of GPT protein] CTD PMID:26763393 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO Zinc Sulfate inhibits the reaction [Ethanol results in decreased expression of GPX1 protein] CTD PMID:15920153 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Grk1 G protein-coupled receptor kinase 1 multiple interactions
decreases expression
EXP 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Zinc Sulfate results in decreased expression of GRK1 protein]; Metipranolol inhibits the reaction [Zinc Sulfate results in decreased expression of GRK1 protein] CTD PMID:16799065 NCBI chr16:81,153,489...81,165,442
Ensembl chr16:81,153,489...81,165,442
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
ISO
EXP
[Ethanol co-treated with Zinc Sulfate] results in increased expression of GSR protein
Zinc Sulfate results in decreased activity of GSR protein
Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]]; Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]]; Acetylcysteine inhibits the reaction [Zinc Sulfate results in decreased activity of GSR protein]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in decreased activity of GSR protein]]; Acetylcysteine promotes the reaction [Zinc Sulfate inhibits the reaction [EUK-134 results in decreased activity of GSR protein]]; EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]]; EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]]; EUK-134 inhibits the reaction [Zinc Sulfate results in decreased activity of GSR protein]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in decreased activity of GSR protein]]; Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]; Zinc Sulfate inhibits the reaction [Carmustine results in decreased activity of GSR protein]; Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]
CTD PMID:15920153, PMID:20046642, PMID:20553223, PMID:25724285 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 multiple interactions
increases expression
increases activity
EXP [Acetylcysteine co-treated with EUK-134] promotes the reaction [[Zinc Sulfate co-treated with Paraquat] results in increased activity of GSTA4 protein]; [EUK-134 co-treated with Acetylcysteine] promotes the reaction [Zinc Sulfate results in increased activity of GSTA4 protein]; [Zinc Sulfate co-treated with Paraquat] results in increased activity of GSTA4 protein; Paraquat promotes the reaction [Zinc Sulfate results in increased expression of GSTA4 mRNA]; Zinc Sulfate promotes the reaction [Paraquat results in increased expression of GSTA4 mRNA] CTD PMID:20553223, PMID:25724285 NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879
JBrowse link
G H2az2 H2A.Z variant histone 2 decreases expression ISO Zinc Sulfate results in decreased expression of H2AZ2 mRNA CTD PMID:12756304 NCBI chr14:86,687,782...86,706,639
Ensembl chr14:86,687,782...86,706,626
JBrowse link
G H2bc12 H2B clustered histone 12 decreases expression ISO Zinc Sulfate results in decreased expression of H2BC12 mRNA CTD PMID:19013360 NCBI chr17:44,527,421...44,527,801
Ensembl chr17:44,527,421...44,527,801
JBrowse link
G Hgf hepatocyte growth factor multiple interactions ISO [Zinc Sulfate co-treated with HGF protein] results in increased phosphorylation of MAPK1 protein; [Zinc Sulfate co-treated with HGF protein] results in increased phosphorylation of MAPK3 protein; [Zinc Sulfate co-treated with HGF protein] results in increased phosphorylation of MET protein CTD PMID:22374166 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated increases expression ISO Zinc Sulfate results in increased expression of HILPDA mRNA CTD PMID:16330358 NCBI chr 4:56,547,600...56,550,584
Ensembl chr 4:56,549,739...56,549,993
JBrowse link
G Hk1 hexokinase 1 decreases expression EXP Zinc Sulfate results in decreased expression of HK1 mRNA CTD PMID:17074742 NCBI chr20:31,911,460...31,979,780
Ensembl chr20:31,912,262...31,956,649
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression EXP Zinc Sulfate results in decreased expression of HMGCR mRNA CTD PMID:17074742 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 increases expression ISO Zinc Sulfate results in increased expression of HMGCS2 mRNA CTD PMID:16330358 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO
EXP
[Disulfiram co-treated with Zinc Sulfate] results in increased expression of HMOX1 mRNA; Zinc Sulfate promotes the reaction [HSF1 protein binds to HMOX1 promoter]
Zinc Sulfate results in increased expression of HMOX1 mRNA
CTD PMID:16330358, PMID:17074742, PMID:17244614, PMID:23085594, PMID:32712770 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 affects expression ISO Zinc Sulfate affects the expression of HNRNPA1 protein CTD PMID:25162517 NCBI chr 7:144,865,302...144,871,592
Ensembl chr 7:144,865,608...144,871,585
JBrowse link
G Hoxd1 homeo box D1 decreases expression ISO Zinc Sulfate results in decreased expression of HOXD1 mRNA CTD PMID:12756304 NCBI chr 3:61,685,619...61,687,758
Ensembl chr 3:61,685,619...61,687,758
JBrowse link
G Hrh4 histamine receptor H4 decreases expression ISO Zinc Sulfate results in decreased expression of HRH4 mRNA CTD PMID:12756304 NCBI chr18:4,365,429...4,382,599
Ensembl chr18:4,365,429...4,382,599
JBrowse link
G Hs2st1 heparan sulfate 2-O-sulfotransferase 1 decreases expression ISO Zinc Sulfate results in decreased expression of HS2ST1 mRNA CTD PMID:12756304 NCBI chr 2:250,467,428...250,600,517
Ensembl chr 2:250,467,429...250,600,517
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases expression ISO Zinc Sulfate results in decreased expression of HSD11B1 mRNA CTD PMID:12756304 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
JBrowse link
G Hsf1 heat shock transcription factor 1 multiple interactions
increases activity
ISO Zinc Sulfate promotes the reaction [HSF1 protein binds to HMOX1 promoter]; Zinc Sulfate promotes the reaction [HSF1 protein binds to HSPA1A enhancer]; Zinc Sulfate promotes the reaction [HSF1 protein binds to HSPA1A promoter]; Zinc Sulfate promotes the reaction [MTF1 protein binds to HSF1 protein]
Zinc Sulfate results in increased activity of HSF1 protein
CTD PMID:16460681, PMID:17244614 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 decreases expression
affects expression
EXP
ISO
Zinc Sulfate results in decreased expression of HSP90AA1 mRNA
Zinc Sulfate affects the expression of HSP90AA1 protein
CTD PMID:17074742, PMID:25162517 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A affects localization
increases expression
multiple interactions
ISO
EXP
Zinc Sulfate affects the localization of HSPA1A protein
Zinc Sulfate results in increased expression of HSPA1A protein
Zinc Sulfate inhibits the reaction [Famotidine results in decreased expression of HSPA1A protein]; Zinc Sulfate inhibits the reaction [Omeprazole results in decreased expression of HSPA1A protein]
Zinc Sulfate results in increased expression of HSPA1A mRNA; Zinc Sulfate results in increased expression of HSPA1A protein
Zinc Sulfate promotes the reaction [HSF1 protein binds to HSPA1A enhancer]; Zinc Sulfate promotes the reaction [HSF1 protein binds to HSPA1A promoter]
CTD PMID:16239242, PMID:16460681, PMID:16945336, PMID:16949620, PMID:17244614 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression EXP
ISO
Zinc Sulfate results in increased expression of HSPA1B protein
Zinc Sulfate results in increased expression of HSPA1B mRNA
CTD PMID:16984587, PMID:23274768 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like increases expression ISO Zinc Sulfate results in increased expression of HSPA1L mRNA CTD PMID:16330358 NCBI chr20:4,879,998...4,965,191
Ensembl chr20:4,959,294...4,964,963
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 decreases expression ISO Zinc Sulfate results in decreased expression of HSPA4 mRNA CTD PMID:12756304 NCBI chr10:38,601,624...38,642,397
Ensembl chr10:38,601,624...38,642,397
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 affects localization ISO Zinc Sulfate affects the localization of HSPA8 protein CTD PMID:16239242 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Zinc Sulfate inhibits the reaction [TNF protein results in increased secretion of ICAM1 protein] CTD PMID:16606632 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 increases expression EXP Zinc Sulfate results in increased expression of IDH1 mRNA CTD PMID:17074742 NCBI chr 9:71,882,108...71,911,645
Ensembl chr 9:71,882,105...71,900,044
JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 decreases expression ISO Zinc Sulfate results in decreased expression of IFI27 mRNA CTD PMID:12756304 NCBI chr 6:127,327,959...127,334,430
Ensembl chr 6:127,327,959...127,334,428
JBrowse link
G Ifng interferon gamma multiple interactions
increases expression
ISO 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Zinc Sulfate results in increased expression of IFNG mRNA]; Zinc Sulfate inhibits the reaction [IFNG protein results in increased secretion of TNF protein]; Zinc Sulfate inhibits the reaction [nickel sulfate results in increased secretion of IFNG protein] CTD PMID:7747530, PMID:14650623, PMID:21333516 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ifngr1 interferon gamma receptor 1 increases expression ISO Zinc Sulfate results in increased expression of IFNGR1 mRNA CTD PMID:19013360 NCBI chr 1:15,062,380...15,080,815
Ensembl chr 1:15,062,432...15,080,907
JBrowse link
G Ift57 intraflagellar transport 57 increases expression ISO Zinc Sulfate results in increased expression of IFT57 mRNA CTD PMID:16330358 NCBI chr11:53,664,638...53,731,779
Ensembl chr11:53,664,638...53,731,779
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions
decreases expression
EXP Pentetic Acid inhibits the reaction [Zinc Sulfate results in decreased expression of IGF1 mRNA]; Zinc Sulfate affects the reaction [GH protein results in increased expression of IGF1 mRNA] CTD PMID:9685221 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf1r insulin-like growth factor 1 receptor multiple interactions ISO IGF1R mutant form inhibits the reaction [Zinc Sulfate results in increased phosphorylation of AKT1 protein]; IGF1R mutant form inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK1 protein]; IGF1R mutant form inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK3 protein] CTD PMID:19946718 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Il1a interleukin 1 alpha multiple interactions
decreases expression
ISO IL1A protein promotes the reaction [Zinc Sulfate results in increased expression of MT1G mRNA]; Zinc Sulfate inhibits the reaction [TNF protein results in increased expression of IL1A mRNA]; Zinc Sulfate promotes the reaction [IL1A protein results in increased expression of CXCL8 mRNA]
Zinc Sulfate results in decreased expression of IL1A mRNA
CTD PMID:22722935 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta increases secretion
decreases expression
multiple interactions
ISO Zinc Sulfate results in increased secretion of IL1B protein
Zinc Sulfate results in decreased expression of IL1B mRNA
[Disulfiram co-treated with Zinc Sulfate] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Zinc Sulfate inhibits the reaction [nickel sulfate results in increased secretion of IL1B protein]; Zinc Sulfate inhibits the reaction [TNF protein results in increased expression of IL1B mRNA]
CTD PMID:14650623, PMID:22722935, PMID:32712770 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 multiple interactions
increases expression
ISO 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Zinc Sulfate results in increased expression of IL2 mRNA]; Tacrolimus inhibits the reaction [Zinc Sulfate inhibits the reaction [Mitogens results in increased expression of IL2 mRNA]]; Zinc Sulfate inhibits the reaction [Ionomycin results in increased expression of IL2 mRNA]; Zinc Sulfate inhibits the reaction [Mitogens results in increased expression of IL2 mRNA]; Zinc Sulfate inhibits the reaction [Mitogens results in increased secretion of IL2 protein]; Zinc Sulfate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA] CTD PMID:16055081, PMID:21333516 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il23r interleukin 23 receptor decreases expression ISO Zinc Sulfate results in decreased expression of IL23R mRNA CTD PMID:16330358 NCBI chr 4:98,203,788...98,306,729
Ensembl chr 4:98,203,958...98,305,173
JBrowse link
G Il24 interleukin 24 decreases expression ISO Zinc Sulfate results in decreased expression of IL24 mRNA CTD PMID:16330358 NCBI chr13:47,618,451...47,623,849
Ensembl chr13:47,618,452...47,623,849
JBrowse link
G Il4r interleukin 4 receptor increases expression ISO Zinc Sulfate results in increased expression of IL4R mRNA CTD PMID:12756304 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
ISO [Disulfiram co-treated with Zinc Sulfate] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Zinc Sulfate inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; Zinc Sulfate inhibits the reaction [TNF protein results in increased secretion of IL6 protein]
Zinc Sulfate results in decreased expression of IL6 mRNA
CTD PMID:16606632, PMID:22722935, PMID:32712770 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6st interleukin 6 signal transducer multiple interactions
decreases expression
ISO Zinc Sulfate inhibits the reaction [TNF protein results in increased secretion of IL6ST protein]
Zinc Sulfate results in decreased expression of IL6ST mRNA
CTD PMID:16330358, PMID:16606632 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944
JBrowse link
G Ints6 integrator complex subunit 6 increases expression ISO Zinc Sulfate results in increased expression of INTS6 mRNA CTD PMID:12756304 NCBI chr15:45,844,050...45,929,996
Ensembl chr15:45,858,608...45,947,030
JBrowse link
G Iqgap2 IQ motif containing GTPase activating protein 2 increases expression ISO Zinc Sulfate results in increased expression of IQGAP2 mRNA CTD PMID:19013360 NCBI chr 2:26,161,628...26,439,067
Ensembl chr 2:26,167,199...26,438,790
JBrowse link
G Itgam integrin subunit alpha M increases expression ISO Zinc Sulfate results in increased expression of ITGAM mRNA CTD PMID:32712770 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Jph3 junctophilin 3 increases expression ISO Zinc Sulfate results in increased expression of JPH3 mRNA CTD PMID:16330358 NCBI chr19:54,553,419...54,613,477
Ensembl chr19:54,553,419...54,613,477
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases phosphorylation
increases activity
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc Sulfate results in increased activity of JUN protein]
Zinc Sulfate results in increased phosphorylation of JUN protein
CTD PMID:9728050, PMID:16606632 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kat8 lysine acetyltransferase 8 increases expression ISO Zinc Sulfate results in increased expression of KAT8 mRNA CTD PMID:15226459 NCBI chr 1:199,360,645...199,372,925
Ensembl chr 1:199,360,645...199,372,923
JBrowse link
G Kazn kazrin, periplakin interacting protein increases expression ISO Zinc Sulfate results in increased expression of KAZN mRNA CTD PMID:12756304 NCBI chr 5:160,637,235...161,730,513
Ensembl chr 5:160,639,578...160,742,479
JBrowse link
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 increases expression EXP Zinc Sulfate results in increased expression of KCNJ5 mRNA CTD PMID:17074742 NCBI chr 8:33,435,493...33,463,410
Ensembl chr 8:33,433,905...33,463,467
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 increases expression EXP Zinc Sulfate results in increased expression of KCNJ8 mRNA CTD PMID:17074742 NCBI chr 4:176,783,287...176,789,143
Ensembl chr 4:176,782,498...176,789,304
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 increases expression EXP Zinc Sulfate results in increased expression of KCNQ1 mRNA CTD PMID:17074742 NCBI chr 1:216,293,087...216,630,339
Ensembl chr 1:216,293,087...216,630,339
JBrowse link
G Kdr kinase insert domain receptor decreases expression EXP Zinc Sulfate results in decreased expression of KDR mRNA CTD PMID:17074742 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Klf15 Kruppel-like factor 15 increases expression EXP Zinc Sulfate results in increased expression of KLF15 mRNA CTD PMID:17074742 NCBI chr 4:122,364,688...122,377,690
Ensembl chr 4:122,365,093...122,377,659
JBrowse link
G Klf9 Kruppel-like factor 9 increases expression EXP Zinc Sulfate results in increased expression of KLF9 mRNA CTD PMID:17074742 NCBI chr 1:240,908,483...240,933,198
Ensembl chr 1:240,908,483...240,933,198
JBrowse link
G Klk8 kallikrein related-peptidase 8 decreases activity ISO Zinc Sulfate results in decreased activity of KLK8 protein CTD PMID:16800733 NCBI chr 1:99,735,168...99,742,011
Ensembl chr 1:99,734,993...99,742,009
JBrowse link
G Klrc3 killer cell lectin like receptor C3 decreases expression ISO Zinc Sulfate results in decreased expression of KLRC3 mRNA CTD PMID:16330358 NCBI chr 4:163,416,373...163,427,331
Ensembl chr 4:163,416,351...163,445,302
JBrowse link
G Lama4 laminin subunit alpha 4 decreases expression ISO Zinc Sulfate results in decreased expression of LAMA4 mRNA CTD PMID:12756304 NCBI chr20:44,060,715...44,201,966
Ensembl chr20:44,060,731...44,209,614
JBrowse link
G Lep leptin decreases expression
multiple interactions
EXP Zinc Sulfate deficiency results in decreased expression of LEP mRNA
Zinc Sulfate deficiency results in decreased expression of and results in decreased secretion of LEP protein
CTD PMID:11568307 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lilra5 leukocyte immunoglobulin like receptor A5 decreases expression ISO Zinc Sulfate results in decreased expression of LILRA5 mRNA CTD PMID:19013360 NCBI chr 1:73,655,767...73,682,232
Ensembl chr 1:73,656,028...73,682,247
JBrowse link
G Lpin2 lipin 2 decreases expression ISO Zinc Sulfate results in decreased expression of LPIN2 mRNA CTD PMID:16330358 NCBI chr 9:119,517,101...119,591,533
Ensembl chr 9:119,517,101...119,591,533
JBrowse link
G Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 increases expression ISO Zinc Sulfate results in increased expression of MAGI1 mRNA CTD PMID:16330358 NCBI chr 4:125,684,816...126,300,013
Ensembl chr 4:125,687,307...125,958,112
JBrowse link
G Mal mal, T-cell differentiation protein increases expression ISO Zinc Sulfate results in increased expression of MAL mRNA CTD PMID:15226459 NCBI chr 3:120,209,647...120,233,655
Ensembl chr 3:120,209,647...120,233,655
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions
increases phosphorylation
ISO 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAP2K1 protein]; MRAS mutant form inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAP2K1 protein]; Zinc Sulfate results in increased phosphorylation of and results in increased activity of MAP2K1 protein CTD PMID:10564177, PMID:11943669 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 multiple interactions
increases phosphorylation
ISO 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAP2K2 protein]; MRAS mutant form inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAP2K2 protein]; Zinc Sulfate results in increased phosphorylation of and results in increased activity of MAP2K2 protein CTD PMID:10564177, PMID:11943669 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 decreases expression EXP Zinc Sulfate results in decreased expression of MAP3K1 mRNA CTD PMID:17074742 NCBI chr 2:43,329,516...43,393,203
Ensembl chr 2:43,329,516...43,393,207
JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 decreases expression ISO Zinc Sulfate results in decreased expression of MAP3K13 mRNA CTD PMID:16330358 NCBI chr11:82,744,391...82,938,357
Ensembl chr11:82,745,735...82,938,357
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO
EXP
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK1 protein]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK1 protein]; IGF1R mutant form inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK1 protein]; KN 62 inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK1 protein]; KN 93 inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK1 protein]; KN 93 promotes the reaction [wortmannin inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK1 protein]]; MRAS mutant form inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK1 protein]; wortmannin inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK1 protein]; wortmannin promotes the reaction [KN 93 inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK1 protein]]; Zinc Sulfate results in increased phosphorylation of and results in increased activity of MAPK1 protein
RTKI cpd inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK1 protein]; tyrphostin AG 1024 inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK1 protein]
[Zinc Sulfate co-treated with HGF protein] results in increased phosphorylation of MAPK1 protein
CTD PMID:9728050, PMID:10564177, PMID:11943669, PMID:15355987, PMID:16606632, PMID:19946718, PMID:22374166 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO
EXP
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK3 protein]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK3 protein]; IGF1R mutant form inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK3 protein]; KN 62 inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK3 protein]; KN 93 inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK3 protein]; KN 93 promotes the reaction [wortmannin inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK3 protein]]; MRAS mutant form inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK3 protein]; wortmannin inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK3 protein]; wortmannin promotes the reaction [KN 93 inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK3 protein]]; Zinc Sulfate results in increased phosphorylation of and results in increased activity of MAPK3 protein
[Zinc Sulfate co-treated with HGF protein] results in increased phosphorylation of MAPK3 protein
RTKI cpd inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK3 protein]; tyrphostin AG 1024 inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK3 protein]
CTD PMID:10564177, PMID:11943669, PMID:15355987, PMID:16606632, PMID:19946718, PMID:22374166 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 increases expression ISO Zinc Sulfate results in increased expression of MAPK7 mRNA CTD PMID:16330358 NCBI chr10:47,768,592...47,775,130
Ensembl chr10:47,766,680...47,775,055
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO Zinc Sulfate results in increased phosphorylation of MAPK8 protein CTD PMID:16606632 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mbnl2 muscleblind-like splicing regulator 2 decreases expression ISO Zinc Sulfate results in decreased expression of MBNL2 mRNA CTD PMID:12756304 NCBI chr15:105,640,097...105,797,933
Ensembl chr15:105,640,097...105,797,932
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase multiple interactions ISO [Zinc Sulfate co-treated with HGF protein] results in increased phosphorylation of MET protein CTD PMID:22374166 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO Zinc Sulfate inhibits the reaction [TNF protein results in increased secretion of MMP9 protein] CTD PMID:16606632 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mog myelin oligodendrocyte glycoprotein decreases expression ISO Zinc Sulfate results in decreased expression of MOG mRNA CTD PMID:16330358 NCBI chr20:2,003,871...2,014,284
Ensembl chr20:2,004,052...2,014,286
JBrowse link
G Mphosph6 M phase phosphoprotein 6 decreases expression ISO Zinc Sulfate results in decreased expression of MPHOSPH6 mRNA CTD PMID:16330358 NCBI chr19:50,357,314...50,367,137
Ensembl chr19:50,357,338...50,367,187
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity
EXP Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased activity of MPO protein]]; Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased activity of MPO protein]]; Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased activity of MPO protein]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased activity of MPO protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased activity of MPO protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in increased activity of MPO protein]]; EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased activity of MPO protein]]; EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased activity of MPO protein]]; EUK-134 inhibits the reaction [Zinc Sulfate results in increased activity of MPO protein]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased activity of MPO protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased activity of MPO protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased activity of MPO protein]]; Paraquat promotes the reaction [Zinc Sulfate results in increased activity of MPO protein]; Zinc Sulfate promotes the reaction [Paraquat results in increased activity of MPO protein] CTD PMID:25724285 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mpst mercaptopyruvate sulfurtransferase decreases expression EXP Zinc Sulfate results in decreased expression of MPST mRNA CTD PMID:17074742 NCBI chr 7:119,626,636...119,631,317
Ensembl chr 7:119,626,637...119,631,425
JBrowse link
G Mras muscle RAS oncogene homolog multiple interactions
increases activity
ISO 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [Zinc Sulfate results in increased activity of MRAS protein]; MRAS mutant form inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAP2K1 protein]; MRAS mutant form inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAP2K2 protein]; MRAS mutant form inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK1 protein]; MRAS mutant form inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK3 protein] CTD PMID:11943669 NCBI chr 8:107,629,028...107,656,851
Ensembl chr 8:107,629,028...107,681,512
JBrowse link
G Mrc1 mannose receptor, C type 1 increases expression ISO Zinc Sulfate results in increased expression of MRC1 mRNA CTD PMID:32712770 NCBI chr17:81,352,700...81,433,743
Ensembl chr17:81,352,700...81,433,743
JBrowse link
G Mrpl12 mitochondrial ribosomal protein L12 increases expression ISO Zinc Sulfate results in increased expression of MRPL12 mRNA CTD PMID:19013360 NCBI chr10:109,658,032...109,662,535
Ensembl chr10:109,658,032...109,662,535
JBrowse link
G Mst1 macrophage stimulating 1 decreases expression ISO Zinc Sulfate results in decreased expression of MST1 mRNA CTD PMID:16330358 NCBI chr 8:116,857,716...116,862,286
Ensembl chr 8:116,857,684...116,862,423
JBrowse link
G Mt1 metallothionein 1 multiple interactions
increases expression
decreases expression
ISO
EXP
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Zinc Sulfate results in increased expression of MT1 mRNA]; [Ethanol co-treated with Zinc Sulfate] results in increased expression of MT1 protein; bisindolylmaleimide I inhibits the reaction [Zinc Sulfate results in increased expression of MT1 mRNA]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Zinc Sulfate results in increased expression of MT1 mRNA]; Dicumarol inhibits the reaction [Zinc Sulfate results in increased expression of MT1 mRNA]; Staurosporine inhibits the reaction [Zinc Sulfate results in increased expression of MT1 mRNA]
Zinc Sulfate results in increased expression of MT1A mRNA
gluconic acid inhibits the reaction [Zinc Sulfate promotes the reaction [Aflatoxin B1 results in increased expression of MT1A mRNA]]; Zinc Sulfate promotes the reaction [Aflatoxin B1 results in increased expression of MT1A mRNA]; Zinc Sulfate promotes the reaction [Nitroprusside results in increased expression of MT1A mRNA]
Zinc Sulfate results in increased expression of MT1A mRNA; Zinc Sulfate results in increased expression of MT1A protein
Zinc Sulfate deficiency results in decreased expression of MT1A mRNA
[Zinc Sulfate co-treated with Cadmium Chloride] results in increased expression of MT1A mRNA; [Zinc Sulfate co-treated with EGF protein] results in increased expression of MT1A mRNA; [Zinc Sulfate co-treated with ferrous sulfate] results in increased expression of and affects the localization of MT1A protein; Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]]; Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A protein]]; Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A mRNA]]; Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A protein]]; Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]; Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT1A protein]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A mRNA]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in increased expression of MT1A protein]]; EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]]; EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A protein]]; EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A mRNA]]; EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A protein]]; EUK-134 inhibits the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]; EUK-134 inhibits the reaction [Zinc Sulfate results in increased expression of MT1A protein]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A mRNA]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT1A protein]]; Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]; Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A protein]; Zinc Sulfate inhibits the reaction [Zinc deficiency results in decreased expression of MT1A mRNA]; Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A mRNA]; Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A protein]; Zinc Sulfate results in increased expression of and affects the localization of MT1A protein
Zinc Sulfate deficiency results in decreased expression of MT1 mRNA
CTD PMID:2219126, PMID:3609024, PMID:7705776, PMID:10952993, PMID:11208937, PMID:15142038, PMID:15884113, PMID:15920153, PMID:17018880, PMID:17074742, PMID:17241390, PMID:19083439, PMID:19679144, PMID:20553223, PMID:23085594, PMID:25724285, PMID:25895165, PMID:26763393, PMID:27017951 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A multiple interactions
increases expression
ISO
EXP
Arachidonic Acid promotes the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]; gluconic acid inhibits the reaction [Zinc Sulfate promotes the reaction [Aflatoxin B1 results in increased expression of MT2A mRNA]]; PTEN promotes the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]; Zinc Sulfate promotes the reaction [Aflatoxin B1 results in increased expression of MT2A mRNA]; Zinc Sulfate promotes the reaction [MTF1 protein binds to MT2A enhancer]; Zinc Sulfate promotes the reaction [Nitroprusside results in increased expression of MT2A mRNA]
Zinc Sulfate results in increased expression of MT2 mRNA
Zinc Sulfate results in increased expression of MT2A mRNA; Zinc Sulfate results in increased expression of MT2A protein
[Zinc Sulfate co-treated with ferrous sulfate] results in increased expression of and affects the localization of MT2A protein; Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]]; Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A protein]]; Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A mRNA]]; Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A protein]]; Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]; Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT2A protein]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A mRNA]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in increased expression of MT2A protein]]; EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]]; EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A protein]]; EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A mRNA]]; EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A protein]]; EUK-134 inhibits the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]; EUK-134 inhibits the reaction [Zinc Sulfate results in increased expression of MT2A protein]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A mRNA]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT2A protein]]; Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]; Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A protein]; Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A mRNA]; Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A protein]; Zinc Sulfate results in increased expression of and affects the localization of MT2A protein
CTD PMID:10362023, PMID:12566070, PMID:15226459, PMID:16460681, PMID:17018880, PMID:17241390, PMID:17409708, PMID:20553223, PMID:21883094, PMID:25724285, PMID:26763393, PMID:27017951 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mtf1 metal-regulatory transcription factor 1 multiple interactions
increases expression
increases activity
ISO MTF1 mutant form inhibits the reaction [Zinc Sulfate results in increased expression of SLC30A1 mRNA]; Nitroprusside promotes the reaction [Zinc Sulfate results in increased expression of MTF1 mRNA]; Zinc Sulfate affects the phosphorylation of and affects the localization of MTF1 protein; Zinc Sulfate promotes the reaction [MTF1 protein binds to HSF1 protein]; Zinc Sulfate promotes the reaction [MTF1 protein binds to MT2A enhancer]
Zinc Sulfate results in increased expression of MTF1 protein
Zinc Sulfate results in increased expression of MTF1 mRNA; Zinc Sulfate results in increased expression of MTF1 protein
Zinc Sulfate results in increased activity of MTF1 protein
CTD PMID:11213479, PMID:16460681, PMID:17018880, PMID:21883094, PMID:24962574, PMID:25162517 NCBI chr 5:142,797,340...142,843,896
Ensembl chr 5:142,797,366...142,842,122
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 decreases expression ISO Zinc Sulfate results in decreased expression of MTHFD1 mRNA CTD PMID:12756304 NCBI chr 6:99,282,850...99,350,367
Ensembl chr 6:99,282,850...99,350,340
JBrowse link
G Mtus1 microtubule associated scaffold protein 1 increases expression EXP Zinc Sulfate results in increased expression of MTUS1 mRNA CTD PMID:17074742 NCBI chr16:54,240,892...54,386,131
Ensembl chr16:54,291,251...54,386,129
JBrowse link
G Myef2 myelin expression factor 2 increases expression ISO Zinc Sulfate results in increased expression of MYEF2 mRNA CTD PMID:16330358 NCBI chr 3:117,353,490...117,389,582
Ensembl chr 3:117,354,382...117,389,561
JBrowse link
G Myh7 myosin heavy chain 7 increases expression EXP Zinc Sulfate results in increased expression of MYH7 mRNA CTD PMID:17074742 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089
JBrowse link
G Nab2 Ngfi-A binding protein 2 increases expression ISO Zinc Sulfate results in increased expression of NAB2 mRNA CTD PMID:12756304 NCBI chr 7:70,963,580...70,971,471
Ensembl chr 7:70,961,575...70,969,905
JBrowse link
G Ncln nicalin increases expression ISO Zinc Sulfate results in increased expression of NCLN mRNA CTD PMID:12756304 NCBI chr 7:11,081,544...11,091,583
Ensembl chr 7:11,081,536...11,091,584
JBrowse link
G Ncr2 natural cytotoxicity triggering receptor 2 increases expression ISO Zinc Sulfate results in increased expression of NCR2 mRNA CTD PMID:16330358 NCBI chr 9:14,779,496...14,787,872 JBrowse link
G Necab2 N-terminal EF-hand calcium binding protein 2 increases expression ISO Zinc Sulfate results in increased expression of NECAB2 mRNA CTD PMID:19013360 NCBI chr19:52,086,325...52,112,633
Ensembl chr19:52,086,325...52,112,629
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase increases expression
multiple interactions
ISO
EXP
Zinc Sulfate results in increased expression of NEDD4 protein
Zinc Sulfate results in increased expression of NEDD4 mRNA; Zinc Sulfate results in increased expression of NEDD4 protein
Wortmannin inhibits the reaction [Zinc Sulfate promotes the reaction [PTEN protein binds to NEDD4 protein]]; Zinc Sulfate promotes the reaction [PTEN protein binds to NEDD4 protein]
CTD PMID:20100827 NCBI chr 8:79,323,408...79,408,842
Ensembl chr 8:79,323,408...79,408,833
JBrowse link
G Nefm neurofilament medium increases expression ISO Zinc Sulfate results in increased expression of NEFM mRNA CTD PMID:19013360 NCBI chr15:44,855,307...44,860,604
Ensembl chr15:44,855,310...44,860,604
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions ISO [Cryptoxanthins co-treated with Zinc Sulfate] results in decreased expression of NFATC1 mRNA; [CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] results in decreased expression of NFATC1 mRNA; [Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in decreased expression of NFATC1 mRNA; Cryptoxanthins promotes the reaction [[Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in decreased expression of NFATC1 mRNA]; Genistein promotes the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] results in decreased expression of NFATC1 mRNA] CTD PMID:17295206, PMID:18636177 NCBI chr18:77,203,517...77,322,690
Ensembl chr18:77,203,525...77,322,690
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 affects expression ISO Zinc Sulfate affects the expression of NFKB1 mRNA CTD PMID:20385217 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO Zinc Sulfate inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein] CTD PMID:16606632 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nfkbib NFKB inhibitor beta decreases expression ISO Zinc Sulfate results in decreased expression of NFKBIB mRNA CTD PMID:12756304 NCBI chr 1:86,941,073...86,948,845
Ensembl chr 1:86,941,074...86,948,845
JBrowse link
G Nkx3-2 NK3 homeobox 2 increases expression ISO Zinc Sulfate results in increased expression of NKX3-2 mRNA CTD PMID:12756304 NCBI chr14:73,813,531...73,818,489
Ensembl chr14:73,813,528...73,815,757
JBrowse link
G Npas2 neuronal PAS domain protein 2 decreases expression ISO Zinc Sulfate results in decreased expression of NPAS2 mRNA CTD PMID:12756304 NCBI chr 9:45,901,262...46,081,880
Ensembl chr 9:45,901,741...46,081,880
JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 increases expression EXP Zinc Sulfate results in increased expression of NR1D2 mRNA CTD PMID:17074742 NCBI chr15:8,730,871...8,757,165
Ensembl chr15:8,730,871...8,757,165
JBrowse link
G Nrg1 neuregulin 1 multiple interactions EXP Zinc Sulfate affects the expression of and affects the splicing of NRG1 mRNA CTD PMID:10878590 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Nsmaf neutral sphingomyelinase activation associated factor increases expression ISO Zinc Sulfate results in increased expression of NSMAF mRNA CTD PMID:16330358 NCBI chr 5:19,499,111...19,560,308
Ensembl chr 5:19,499,480...19,559,393
JBrowse link
G Ocln occludin multiple interactions ISO Zinc Sulfate inhibits the reaction [Patulin results in increased degradation of OCLN protein] CTD PMID:19013514 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase increases expression ISO Zinc Sulfate results in increased expression of OGT mRNA CTD PMID:12756304 NCBI chr  X:71,540,870...71,585,906
Ensembl chr  X:71,528,988...71,585,908
JBrowse link
G Pa2g4 proliferation-associated 2G4 affects expression ISO Zinc Sulfate affects the expression of PA2G4 protein CTD PMID:25162517 NCBI chr 7:2,979,587...2,987,055
Ensembl chr 7:2,979,588...2,987,055
JBrowse link
G Pabpn1 poly(A) binding protein, nuclear 1 multiple interactions ISO Zinc Sulfate inhibits the reaction [PABPN1 protein mutant form binds to PABPN1 protein mutant form] CTD PMID:16239242 NCBI chr15:33,555,640...33,560,251
Ensembl chr15:33,555,640...33,560,242
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
decreases expression
multiple interactions
ISO
EXP
Zinc Sulfate results in increased cleavage of PARP1 protein
Zinc Sulfate results in decreased expression of PARP1 protein
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Zinc Sulfate results in decreased expression of PARP1 protein]; Metipranolol inhibits the reaction [Zinc Sulfate results in decreased expression of PARP1 protein]
CTD PMID:16799065 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pcdhb20 protocadherin beta 20 increases expression ISO Zinc Sulfate results in increased expression of PCDHB14 mRNA CTD PMID:16330358 NCBI chr18:30,581,530...30,584,905
Ensembl chr18:30,581,530...30,584,905
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP [Ethanol co-treated with Zinc Sulfate] results in increased expression of PCNA protein CTD PMID:16865776 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pde8a phosphodiesterase 8A decreases expression ISO Zinc Sulfate results in decreased expression of PDE8A mRNA CTD PMID:12756304 NCBI chr 1:143,036,083...143,160,395
Ensembl chr 1:143,036,218...143,159,433
JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 decreases expression EXP Zinc Sulfate results in decreased expression of PDIA6 mRNA CTD PMID:17074742 NCBI chr 6:42,568,269...42,585,654
Ensembl chr 6:42,568,220...42,585,652
JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 increases expression EXP Zinc Sulfate results in increased expression of PDK2 mRNA CTD PMID:17074742 NCBI chr10:82,838,270...82,852,758
Ensembl chr10:82,839,153...82,852,660
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression EXP Zinc Sulfate results in increased expression of PDK4 mRNA CTD PMID:17074742 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Pdlim7 PDZ and LIM domain 7 decreases expression ISO Zinc Sulfate results in decreased expression of PDLIM7 mRNA CTD PMID:16330358 NCBI chr17:9,653,510...9,668,715
Ensembl chr17:9,653,561...9,668,712
JBrowse link
G Pdp1 pyruvate dehyrogenase phosphatase catalytic subunit 1 increases expression EXP Zinc Sulfate results in increased expression of PDP1 mRNA CTD PMID:17074742 NCBI chr 5:25,577,593...25,584,325
Ensembl chr 5:25,577,451...25,584,288
JBrowse link
G Pdp2 pyruvate dehyrogenase phosphatase catalytic subunit 2 decreases expression EXP Zinc Sulfate results in decreased expression of PDP2 mRNA CTD PMID:17074742 NCBI chr19:597,427...601,556
Ensembl chr19:597,427...601,469
JBrowse link
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 decreases expression EXP Zinc Sulfate results in decreased expression of PFKFB2 mRNA CTD PMID:17074742 NCBI chr13:47,413,453...47,440,682
Ensembl chr13:47,413,458...47,440,682
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 increases expression ISO Zinc Sulfate results in increased expression of PFKFB3 mRNA CTD PMID:16330358 NCBI chr17:70,632,778...70,713,736
Ensembl chr17:70,684,134...70,713,726
JBrowse link
G Pfkl phosphofructokinase, liver type decreases expression EXP Zinc Sulfate results in decreased expression of PFKL mRNA CTD PMID:17074742 NCBI chr20:11,393,860...11,415,889
Ensembl chr20:11,393,877...11,415,882
JBrowse link
G Pfkm phosphofructokinase, muscle decreases expression ISO Zinc Sulfate results in decreased expression of PFKM mRNA CTD PMID:12756304 NCBI chr 7:139,702,066...139,722,132
Ensembl chr 7:139,685,573...139,722,132
JBrowse link
G Pgap2 post-GPI attachment to proteins 2 decreases expression ISO Zinc Sulfate results in decreased expression of PGAP2 mRNA CTD PMID:12756304 NCBI chr 1:167,309,021...167,335,550
Ensembl chr 1:167,309,051...167,334,741
JBrowse link
G Pgk1 phosphoglycerate kinase 1 increases expression ISO Zinc Sulfate results in increased expression of PGK1 mRNA CTD PMID:15226459 NCBI chr  X:77,263,399...77,279,373
Ensembl chr  X:77,263,359...77,279,367
JBrowse link
G Phf7 PHD finger protein 7 decreases expression ISO Zinc Sulfate results in decreased expression of PHF7 mRNA CTD PMID:12756304 NCBI chr16:7,323,527...7,336,609
Ensembl chr16:7,323,520...7,336,335
JBrowse link
G Pim3 Pim-3 proto-oncogene, serine/threonine kinase increases expression EXP Zinc Sulfate results in increased expression of PIM3 mRNA CTD PMID:17074742 NCBI chr 7:129,856,467...129,863,441
Ensembl chr 7:129,860,114...129,863,441
JBrowse link
G Pkia cAMP-dependent protein kinase inhibitor alpha increases expression EXP Zinc Sulfate results in increased expression of PKIA mRNA CTD PMID:17074742 NCBI chr 2:96,593,185...96,668,222
Ensembl chr 2:96,595,088...96,668,222
JBrowse link
G Pla2g4a phospholipase A2 group IVA increases expression EXP Zinc Sulfate results in increased expression of PLA2G4A mRNA CTD PMID:17074742 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Plcb4 phospholipase C, beta 4 increases expression EXP Zinc Sulfate results in increased expression of PLCB4 mRNA CTD PMID:17074742 NCBI chr 3:128,601,163...128,971,720
Ensembl chr 3:128,756,799...128,971,746
JBrowse link
G Plch1 phospholipase C, eta 1 decreases expression ISO Zinc Sulfate results in decreased expression of PLCH1 mRNA CTD PMID:12756304 NCBI chr 2:154,256,382...154,468,166
Ensembl chr 2:154,256,380...154,418,920
JBrowse link
G Plppr1 phospholipid phosphatase related 1 decreases expression ISO Zinc Sulfate results in decreased expression of PLPPR1 mRNA CTD PMID:16330358 NCBI chr 5:67,852,817...67,985,310
Ensembl chr 5:67,852,180...68,139,199
JBrowse link
G Pnma2 PNMA family member 2 decreases expression ISO Zinc Sulfate results in decreased expression of PNMA2 mRNA CTD PMID:12756304 NCBI chr15:43,581,874...43,589,680
Ensembl chr15:43,582,020...43,589,680
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP Zinc Sulfate results in increased expression of POR mRNA CTD PMID:17074742 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Pou4f2 POU class 4 homeobox 2 decreases expression ISO Zinc Sulfate results in decreased expression of POU4F2 mRNA CTD PMID:12756304 NCBI chr19:33,160,180...33,163,821
Ensembl chr19:33,160,180...33,163,821
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate co-treated with Ethanol] results in increased expression of PPARA protein CTD PMID:20118189 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B decreases expression EXP Zinc Sulfate results in decreased expression of PPM1B mRNA CTD PMID:17074742 NCBI chr 6:8,219,385...8,280,127
Ensembl chr 6:8,218,696...8,280,124
JBrowse link
G Ppp1r3c protein phosphatase 1, regulatory subunit 3C increases expression ISO Zinc Sulfate results in increased expression of PPP1R3C mRNA CTD PMID:16330358 NCBI chr 1:255,371,830...255,376,833
Ensembl chr 1:255,371,810...255,376,833
JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha decreases response to substance ISO PPP2R1A protein results in decreased susceptibility to Zinc Sulfate CTD PMID:24962574 NCBI chr 1:60,717,386...60,736,629
Ensembl chr 1:60,717,386...60,736,609
JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta affects expression ISO Zinc Sulfate affects the expression of PPP2R1B protein CTD PMID:25162517 NCBI chr 8:55,279,278...55,311,768
Ensembl chr 8:55,279,373...55,301,320
JBrowse link
G Ppp2r2d protein phosphatase 2, regulatory subunit B, delta increases expression ISO Zinc Sulfate results in increased expression of PPP2R2D mRNA CTD PMID:12756304 NCBI chr 1:211,205,903...211,240,216
Ensembl chr 1:211,205,903...211,239,888
JBrowse link
G Ppp2r5b protein phosphatase 2, regulatory subunit B', beta decreases response to substance ISO PPP2R5B protein results in decreased susceptibility to Zinc Sulfate CTD PMID:24962574 NCBI chr 1:221,597,294...221,605,467
Ensembl chr 1:221,597,296...221,605,400
JBrowse link
G Prpsap2 phosphoribosyl pyrophosphate synthetase-associated protein 2 increases expression EXP Zinc Sulfate results in increased expression of PRPSAP2 mRNA CTD PMID:17074742 NCBI chr10:48,008,799...48,044,435
Ensembl chr10:48,008,802...48,044,344
JBrowse link
G Prr3 proline rich 3 increases expression ISO Zinc Sulfate results in increased expression of PRR3 mRNA CTD PMID:16330358 NCBI chr20:3,300,247...3,307,262
Ensembl chr20:3,299,730...3,307,673
JBrowse link
G Psmb2 proteasome 20S subunit beta 2 decreases expression ISO Zinc Sulfate results in decreased expression of PSMB2 mRNA CTD PMID:12756304 NCBI chr 5:144,702,004...144,734,220
Ensembl chr 5:144,701,949...144,734,257
JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 decreases expression ISO Zinc Sulfate results in decreased expression of PSMC5 mRNA CTD PMID:12756304 NCBI chr10:94,445,877...94,451,811
Ensembl chr10:94,445,877...94,451,811
JBrowse link
G Ptcra pre T-cell antigen receptor alpha decreases expression ISO Zinc Sulfate results in decreased expression of PTCRA mRNA CTD PMID:19013360 NCBI chr 9:16,528,970...16,539,383
Ensembl chr 9:16,529,579...16,539,472
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions
increases ubiquitination
increases response to substance
decreases expression
ISO
EXP
PTEN mutant form inhibits the reaction [Zinc Sulfate results in increased expression of SLC30A1 mRNA]; PTEN promotes the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]
Zinc Sulfate results in increased ubiquitination of PTEN protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zinc Sulfate results in decreased stability of PTEN protein]; Wortmannin inhibits the reaction [Zinc Sulfate promotes the reaction [PTEN protein binds to NEDD4 protein]]; Wortmannin inhibits the reaction [Zinc Sulfate results in decreased expression of PTEN protein]; Wortmannin inhibits the reaction [Zinc Sulfate results in increased ubiquitination of PTEN protein]; Zinc Sulfate promotes the reaction [PTEN protein binds to NEDD4 protein]; Zinc Sulfate results in decreased expression of and results in decreased stability of PTEN protein
PTEN protein results in increased susceptibility to Zinc Sulfate
CTD PMID:20100827, PMID:21883094 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptges2 prostaglandin E synthase 2 increases expression ISO Zinc Sulfate results in increased expression of PTGES2 mRNA CTD PMID:15226459 NCBI chr 3:11,424,195...11,431,379
Ensembl chr 3:11,424,099...11,431,402
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 decreases activity ISO Zinc Sulfate results in decreased activity of PTPN1 protein CTD PMID:10460753 NCBI chr 3:164,665,462...164,711,936
Ensembl chr 3:164,665,532...164,711,848
JBrowse link
G Ptprd protein tyrosine phosphatase, receptor type, D increases expression EXP Zinc Sulfate results in increased expression of PTPRD mRNA CTD PMID:17074742 NCBI chr 5:92,862,229...93,514,071
Ensembl chr 5:92,862,267...93,244,202
JBrowse link
G Ptprn protein tyrosine phosphatase, receptor type, N increases expression ISO Zinc Sulfate results in increased expression of PTPRN mRNA CTD PMID:19013360 NCBI chr 9:82,446,626...82,462,314
Ensembl chr 9:82,446,633...82,461,903
JBrowse link
G Pts 6-pyruvoyl-tetrahydropterin synthase decreases expression ISO Zinc Sulfate results in decreased expression of PTS mRNA CTD PMID:15226459 NCBI chr 8:54,954,261...54,961,271
Ensembl chr 8:54,954,226...54,961,265
JBrowse link
G Pxk PX domain containing serine/threonine kinase increases expression EXP Zinc Sulfate results in increased expression of PXK mRNA CTD PMID:17074742 NCBI chr15:18,548,209...18,616,617
Ensembl chr15:18,548,212...18,616,589
JBrowse link
G Rab20 RAB20, member RAS oncogene family increases expression ISO Zinc Sulfate results in increased expression of RAB20 mRNA CTD PMID:16330358 NCBI chr16:83,358,116...83,382,326
Ensembl chr16:83,358,116...83,382,326
JBrowse link
G Rack1 receptor for activated C kinase 1 decreases expression
affects expression
ISO Zinc Sulfate results in decreased expression of RACK1 mRNA
Zinc Sulfate affects the expression of RACK1 protein
CTD PMID:12756304, PMID:25162517 NCBI chr10:34,149,717...34,155,198
Ensembl chr10:34,149,717...34,155,198
Ensembl chr12:34,149,717...34,155,198
JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 decreases expression ISO Zinc Sulfate results in decreased expression of RASGRF1 mRNA CTD PMID:12756304 NCBI chr 8:97,277,250...97,405,095
Ensembl chr 8:97,277,456...97,405,102
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression ISO Zinc Sulfate results in decreased expression of RB1 mRNA CTD PMID:12756304 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases activity
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc Sulfate results in decreased activity of RELA protein]; Zinc Sulfate inhibits the reaction [TNF protein affects the localization of RELA protein]; Zinc Sulfate inhibits the reaction [TNF protein results in increased activity of RELA protein]
Zinc Sulfate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein affects the localization of RELA protein]]
CTD PMID:16606632, PMID:16818790 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Repin1 replication initiator 1 increases expression ISO Zinc Sulfate results in increased expression of REPIN1 mRNA CTD PMID:12756304 NCBI chr 4:78,232,454...78,237,498
Ensembl chr 4:78,233,332...78,236,781
JBrowse link
G RGD1306063 similar to HT021 decreases expression ISO Zinc Sulfate results in decreased expression of C3ORF14 mRNA CTD PMID:15226459 NCBI chr15:12,869,217...12,889,144
Ensembl chr15:12,872,408...12,889,108
JBrowse link
G RGD1560108 similar to RIKEN cDNA 2700081O15 increases expression ISO Zinc Sulfate results in increased expression of C11ORF95 mRNA CTD PMID:12756304 NCBI chr 1:222,669,642...222,677,372
Ensembl chr 1:222,672,501...222,677,372
JBrowse link
G Rgn regucalcin multiple interactions
increases expression
ISO Cycloheximide inhibits the reaction [Zinc Sulfate results in increased expression of RGN mRNA]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Zinc Sulfate results in increased expression of RGN mRNA] CTD PMID:18327666 NCBI chr  X:1,833,484...1,848,904
Ensembl chr  X:1,833,492...1,848,904
JBrowse link
G Rgp1 RGP1 homolog, RAB6A GEF complex partner 1 increases expression ISO Zinc Sulfate results in increased expression of RGP1 mRNA CTD PMID:12756304 NCBI chr 5:59,080,290...59,088,777
Ensembl chr 5:59,080,765...59,088,523
JBrowse link
G Rgs19 regulator of G-protein signaling 19 decreases expression EXP Zinc Sulfate results in decreased expression of RGS19 mRNA CTD PMID:17074742 NCBI chr 3:177,196,276...177,204,767
Ensembl chr 3:177,196,687...177,201,525
JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 decreases expression ISO Zinc Sulfate results in decreased expression of RIMS2 mRNA CTD PMID:12756304 NCBI chr 7:78,091,998...78,594,164
Ensembl chr 7:78,092,037...78,594,138
JBrowse link
G Rnh1 ribonuclease/angiogenin inhibitor 1 affects expression ISO Zinc Sulfate affects the expression of RNH1 protein CTD PMID:25162517 NCBI chr 1:214,151,341...214,163,807
Ensembl chr 1:214,151,338...214,163,808
JBrowse link
G Ro60 Ro60, Y RNA binding protein decreases expression ISO Zinc Sulfate results in decreased expression of RO60 mRNA CTD PMID:15226459 NCBI chr13:60,546,892...60,567,882
Ensembl chr13:60,546,912...60,567,882
JBrowse link
G Ror1 receptor tyrosine kinase-like orphan receptor 1 decreases expression ISO Zinc Sulfate results in decreased expression of ROR1 mRNA CTD PMID:12756304 NCBI chr 5:118,892,874...119,239,528
Ensembl chr 5:119,097,715...119,241,733
JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 increases expression ISO Zinc Sulfate results in increased expression of RPS6KA2 mRNA CTD PMID:19013360 NCBI chr 1:53,219,346...53,499,445
Ensembl chr 1:53,360,157...53,499,445
JBrowse link
G Rps6ka6 ribosomal protein S6 kinase A6 increases expression ISO Zinc Sulfate results in increased expression of RPS6KA6 mRNA CTD PMID:19013360 NCBI chr  X:82,641,679...82,743,771
Ensembl chr  X:82,641,687...82,743,753
JBrowse link
G Rrh retinal pigment epithelium derived rhodopsin homolog increases expression ISO Zinc Sulfate results in increased expression of RRH mRNA CTD PMID:19013360 NCBI chr 2:235,237,422...235,250,474
Ensembl chr 2:235,237,414...235,249,575
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions
increases expression
ISO Cycloheximide inhibits the reaction [Zinc Sulfate results in increased expression of RUNX2 mRNA]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Zinc Sulfate results in increased expression of RUNX2 mRNA] CTD PMID:18327666 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Sag S-antigen visual arrestin decreases expression ISO Zinc Sulfate results in decreased expression of SAG mRNA CTD PMID:16330358 NCBI chr 9:94,926,901...94,972,162
Ensembl chr 9:94,928,489...94,972,027
JBrowse link
G Scg3 secretogranin III increases expression ISO Zinc Sulfate results in increased expression of SCG3 mRNA CTD PMID:19013360 NCBI chr 8:82,582,352...82,641,536
Ensembl chr 8:82,582,352...82,641,536
JBrowse link
G Scn1a sodium voltage-gated channel alpha subunit 1 increases expression EXP Zinc Sulfate results in increased expression of SCN1A mRNA CTD PMID:17074742 NCBI chr 3:52,388,811...52,533,365
Ensembl chr 3:52,381,975...52,510,507
JBrowse link
G Sema6b semaphorin 6B increases expression ISO Zinc Sulfate results in increased expression of SEMA6B mRNA CTD PMID:16330358 NCBI chr 9:10,934,273...10,951,252
Ensembl chr 9:10,941,613...10,951,252
JBrowse link
G Septin11 septin 11 decreases expression ISO Zinc Sulfate results in decreased expression of SEPTIN11 mRNA CTD PMID:12756304 NCBI chr14:16,369,544...16,405,645
Ensembl chr14:16,369,544...16,452,998
JBrowse link
G Septin8 septin 8 decreases expression ISO Zinc Sulfate results in decreased expression of SEPTIN8 mRNA CTD PMID:19013360 NCBI chr10:38,877,422...38,906,480
Ensembl chr10:38,877,422...38,906,482
JBrowse link
G Serinc1 serine incorporator 1 decreases expression ISO Zinc Sulfate results in decreased expression of SERINC1 mRNA CTD PMID:12756304 NCBI chr20:38,966,016...38,985,056
Ensembl chr20:38,967,238...38,985,036
JBrowse link
G Sertad4 SERTA domain containing 4 increases expression ISO Zinc Sulfate results in increased expression of SERTAD4 mRNA CTD PMID:16330358 NCBI chr13:111,574,545...111,585,113
Ensembl chr13:111,574,609...111,581,019
JBrowse link
G Sesn2 sestrin 2 multiple interactions ISO Zinc Sulfate inhibits the reaction [prolinedithiocarbamate results in increased expression of SESN2 mRNA] CTD PMID:18951928 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117
JBrowse link
G Sesn3 sestrin 3 decreases expression ISO Zinc Sulfate results in decreased expression of SESN3 mRNA CTD PMID:16330358 NCBI chr 8:12,823,060...12,878,749
Ensembl chr 8:12,823,155...12,872,705
JBrowse link
G Shfl shiftless antiviral inhibitor of ribosomal frameshifting decreases expression ISO Zinc Sulfate results in decreased expression of SHFL mRNA CTD PMID:12756304 NCBI chr 8:21,890,214...21,896,045
Ensembl chr 8:21,890,319...21,896,031
JBrowse link
G Sidt2 SID1 transmembrane family, member 2 increases expression ISO Zinc Sulfate results in increased expression of SIDT2 mRNA CTD PMID:12756304 NCBI chr 8:50,230,335...50,246,979
Ensembl chr 8:50,230,339...50,246,656
JBrowse link
G Slc11a2 solute carrier family 11 member 2 increases expression
multiple interactions
ISO Zinc Sulfate results in increased expression of SLC11A2 mRNA; Zinc Sulfate results in increased expression of SLC11A2 protein
[Zinc Sulfate results in increased expression of SLC11A2 protein] which results in increased uptake of ferric chloride; Zinc Sulfate inhibits the reaction [[Hydrogen Peroxide results in increased expression of SLC11A2 protein] which results in increased uptake of ferric chloride]; Zinc Sulfate inhibits the reaction [Hydrogen Peroxide results in increased expression of SLC11A2 protein]
CTD PMID:19306086, PMID:20096349 NCBI chr 7:142,025,812...142,062,892
Ensembl chr 7:142,025,815...142,063,212
JBrowse link
G Slc12a9 solute carrier family 12, member 9 increases expression ISO Zinc Sulfate results in increased expression of SLC12A9 mRNA CTD PMID:12756304 NCBI chr12:22,434,845...22,451,265
Ensembl chr12:22,434,814...22,451,263
JBrowse link
G Slc18a2 solute carrier family 18 member A2 multiple interactions
decreases expression
EXP Paraquat promotes the reaction [Zinc Sulfate results in decreased expression of SLC18A2 mRNA]; Paraquat promotes the reaction [Zinc Sulfate results in decreased expression of SLC18A2 protein]; Zinc Sulfate promotes the reaction [Paraquat results in decreased expression of SLC18A2 mRNA]; Zinc Sulfate promotes the reaction [Paraquat results in decreased expression of SLC18A2 protein]
Zinc Sulfate results in decreased expression of SLC18A2 mRNA; Zinc Sulfate results in decreased expression of SLC18A2 protein
CTD PMID:20553223 NCBI chr 1:280,397,831...280,457,968
Ensembl chr 1:280,423,079...280,457,148
JBrowse link
G Slc20a1 solute carrier family 20 member 1 decreases expression EXP Zinc Sulfate results in decreased expression of SLC20A1 mRNA CTD PMID:17074742 NCBI chr 3:121,725,204...121,739,160
Ensembl chr 3:121,725,859...121,739,173
JBrowse link
G Slc30a1 solute carrier family 30 member 1 multiple interactions
increases expression
decreases expression
affects localization
ISO
EXP
MTF1 mutant form inhibits the reaction [Zinc Sulfate results in increased expression of SLC30A1 mRNA]; PTEN mutant form inhibits the reaction [Zinc Sulfate results in increased expression of SLC30A1 mRNA]; Zinc Sulfate promotes the reaction [Nitroprusside results in increased expression of SLC30A1 mRNA]
Zinc Sulfate results in increased expression of SLC30A1 mRNA; Zinc Sulfate results in increased expression of SLC30A1 protein
Zinc Sulfate deficiency results in decreased expression of SLC30A1 mRNA
Zinc Sulfate affects the localization of SLC30A1 protein
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Zinc Sulfate results in increased expression of SLC30A1 mRNA]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Zinc Sulfate results in increased expression of SLC30A1 mRNA]; Dicumarol inhibits the reaction [Zinc Sulfate results in increased expression of SLC30A1 mRNA]; Staurosporine inhibits the reaction [Zinc Sulfate results in increased expression of SLC30A1 mRNA]
CTD PMID:9560190, PMID:10952993, PMID:11208937, PMID:12756304, PMID:14608047, PMID:15142038, PMID:15226459, PMID:16330358, PMID:17018880, PMID:19083439, PMID:19679144, PMID:21883094, PMID:25162517, PMID:25895165 NCBI chr13:110,677,810...110,681,683
Ensembl chr13:110,677,810...110,681,683
JBrowse link
G Slc30a2 solute carrier family 30 member 2 affects localization
increases expression
decreases expression
ISO
EXP
Zinc Sulfate affects the localization of SLC30A2 protein
Zinc Sulfate results in increased expression of SLC30A2 mRNA
Zinc Sulfate deficiency results in decreased expression of SLC30A2 mRNA
CTD PMID:11208937, PMID:14608047, PMID:17074742 NCBI chr 5:152,559,577...152,571,800
Ensembl chr 5:152,559,577...152,571,799
JBrowse link
G Slc30a4 solute carrier family 30 member 4 affects localization
decreases expression
ISO
EXP
Zinc Sulfate affects the localization of SLC30A4 protein
Zinc Sulfate deficiency results in decreased expression of SLC30A4 mRNA
CTD PMID:11208937, PMID:14608047 NCBI chr 3:114,805,919...114,828,154
Ensembl chr 3:114,805,922...114,828,154
JBrowse link
G Slc39a1 solute carrier family 39 member 1 decreases expression
increases expression
ISO Zinc Sulfate results in decreased expression of SLC39A1 mRNA; Zinc Sulfate results in decreased expression of SLC39A1 protein
Zinc Sulfate results in increased expression of SLC39A1 mRNA
CTD PMID:15226459, PMID:25162517 NCBI chr 2:189,609,766...189,615,367
Ensembl chr 2:189,609,800...189,615,366
JBrowse link
G Slc39a10 solute carrier family 39 member 10 decreases expression
increases expression
EXP Zinc Sulfate results in decreased expression of SLC39A10 mRNA; Zinc Sulfate results in decreased expression of SLC39A10 protein
Zinc Sulfate results in increased expression of SLC39A10 mRNA; Zinc Sulfate results in increased expression of SLC39A10 protein
CTD PMID:16804107 NCBI chr 9:59,947,562...60,070,549
Ensembl chr 9:60,021,534...60,070,552
JBrowse link
G Slc39a3 solute carrier family 39 member 3 affects localization
decreases expression
ISO Zinc Sulfate affects the localization of SLC39A3 protein
Zinc Sulfate results in decreased expression of SLC39A3 mRNA
CTD PMID:14608047 NCBI chr 7:11,545,073...11,551,074
Ensembl chr 7:11,545,024...11,553,370
JBrowse link
G Slc6a2 solute carrier family 6 member 2 increases expression ISO Zinc Sulfate results in increased expression of SLC6A2 mRNA CTD PMID:16330358 NCBI chr19:15,391,682...15,431,274
Ensembl chr19:15,391,581...15,431,274
JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions
increases expression
EXP Paraquat promotes the reaction [Zinc Sulfate results in increased expression of SLC6A3 mRNA]; Paraquat promotes the reaction [Zinc Sulfate results in increased expression of SLC6A3 protein]; Zinc Sulfate promotes the reaction [Paraquat results in increased expression of SLC6A3 mRNA]; Zinc Sulfate promotes the reaction [Paraquat results in increased expression of SLC6A3 protein]
Zinc Sulfate results in increased expression of SLC6A3 mRNA; Zinc Sulfate results in increased expression of SLC6A3 protein
CTD PMID:20553223 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983
JBrowse link
G Slc9a6 solute carrier family 9 member A6 increases expression ISO Zinc Sulfate results in increased expression of SLC9A6 mRNA CTD PMID:12756304 NCBI chr  X:158,979,081...159,045,019
Ensembl chr  X:158,978,755...159,045,044
JBrowse link
G Slco1c1 solute carrier organic anion transporter family, member 1c1 increases expression ISO Zinc Sulfate results in increased expression of SLCO1C1 mRNA CTD PMID:19013360 NCBI chr 4:175,729,709...175,776,749
Ensembl chr 4:175,729,726...175,776,808
JBrowse link
G Snrk SNF related kinase decreases expression ISO Zinc Sulfate results in decreased expression of SNRK mRNA CTD PMID:16330358 NCBI chr 8:130,749,806...130,805,225
Ensembl chr 8:130,749,838...130,803,597
JBrowse link
G Snrnp70 small nuclear ribonucleoprotein U1 subunit 70 decreases degradation ISO Zinc Sulfate results in decreased degradation of SNRNP70 protein CTD PMID:10455152 NCBI chr 1:101,367,470...101,388,153
Ensembl chr 1:101,367,471...101,388,129
JBrowse link
G Socs2 suppressor of cytokine signaling 2 increases expression ISO Zinc Sulfate results in increased expression of SOCS2 mRNA CTD PMID:16330358 NCBI chr 7:36,495,496...36,500,878
Ensembl chr 7:36,495,480...36,499,784
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [gluconic acid co-treated with Zinc Sulfate] promotes the reaction [Aflatoxin B1 results in increased expression of SOD1 mRNA]; Zinc Sulfate promotes the reaction [Aflatoxin B1 results in increased expression of SOD1 mRNA] CTD PMID:27017951 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO [Disulfiram co-treated with Zinc Sulfate] results in increased expression of SOD2 mRNA CTD PMID:32712770 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sord sorbitol dehydrogenase decreases expression ISO Zinc Sulfate results in decreased expression of SORD mRNA CTD PMID:19013360 NCBI chr 3:114,176,127...114,207,368
Ensembl chr 3:114,176,309...114,207,366
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions ISO Zinc Sulfate inhibits the reaction [Copper Sulfate results in decreased activity of SP1 protein] CTD PMID:26241054 NCBI chr 7:144,014,173...144,044,635
Ensembl chr 7:144,014,173...144,044,629
JBrowse link
G Sptbn1 spectrin, beta, non-erythrocytic 1 decreases expression ISO Zinc Sulfate results in decreased expression of SPTBN1 mRNA CTD PMID:12756304 NCBI chr14:114,517,839...114,700,199
Ensembl chr14:114,518,816...114,692,764
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase decreases activity ISO Zinc Sulfate results in decreased activity of SRC protein CTD PMID:16410015 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 decreases expression ISO Zinc Sulfate results in decreased expression of SRSF5 mRNA CTD PMID:12756304 NCBI chr 6:104,611,026...104,640,033
Ensembl chr 6:104,611,026...104,615,302
JBrowse link
G Srsf7 serine and arginine rich splicing factor 7 affects expression ISO Zinc Sulfate affects the expression of SRSF7 protein CTD PMID:25162517 NCBI chr 6:2,879,312...2,886,505
Ensembl chr 6:2,880,518...2,886,465
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions
increases expression
ISO Zinc Sulfate inhibits the reaction [CNTF protein results in increased phosphorylation of STAT1 protein]
Zinc Sulfate results in increased expression of STAT1 mRNA
CTD PMID:16896058, PMID:19013360 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO Zinc Sulfate inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein] CTD PMID:16896058 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Steap4 STEAP4 metalloreductase decreases expression ISO Zinc Sulfate results in decreased expression of STEAP4 mRNA CTD PMID:12756304 NCBI chr 4:23,112,682...23,135,354
Ensembl chr 4:23,090,029...23,135,354
JBrowse link
G Sulf1 sulfatase 1 increases expression EXP Zinc Sulfate results in increased expression of SULF1 mRNA CTD PMID:17074742 NCBI chr 5:5,999,520...6,186,901
Ensembl chr 5:5,999,475...6,186,329
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 increases expression EXP Zinc Sulfate results in increased expression of SULT1A1 mRNA CTD PMID:17074742 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Synrg synergin, gamma increases expression ISO Zinc Sulfate results in increased expression of SYNRG mRNA CTD PMID:12756304 NCBI chr10:71,278,698...71,357,791 JBrowse link
G Tas1r3 taste 1 receptor member 3 affects response to substance ISO TAS1R3 protein affects the susceptibility to Zinc Sulfate CTD PMID:19244541 NCBI chr 5:173,307,325...173,312,950
Ensembl chr 5:173,308,870...173,312,023
JBrowse link
G Tas2r144 taste receptor, type 2, member 144 increases expression ISO Zinc Sulfate results in increased expression of TAS2R40 mRNA CTD PMID:16330358 NCBI chr 4:71,588,974...71,589,933
Ensembl chr 4:71,588,974...71,589,933
JBrowse link
G Tbc1d8 TBC1 domain family, member 8 increases expression ISO Zinc Sulfate results in increased expression of TBC1D8 mRNA CTD PMID:12756304 NCBI chr 9:46,090,613...46,206,672
Ensembl chr 9:46,090,019...46,206,605
JBrowse link
G Tbx3 T-box transcription factor 3 decreases expression ISO Zinc Sulfate results in decreased expression of TBX3 mRNA CTD PMID:16330358 NCBI chr12:42,479,518...42,494,588
Ensembl chr12:42,480,560...42,492,526
JBrowse link
G Tbxa2r thromboxane A2 receptor decreases expression ISO Zinc Sulfate results in decreased expression of TBXA2R mRNA CTD PMID:12756304 NCBI chr 7:11,253,153...11,259,233
Ensembl chr 7:11,253,180...11,257,977
JBrowse link
G Th tyrosine hydroxylase multiple interactions
decreases expression
EXP Paraquat promotes the reaction [Zinc Sulfate results in decreased expression of TH protein]; Zinc Sulfate promotes the reaction [Paraquat results in decreased expression of TH protein] CTD PMID:20553223 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Thbd thrombomodulin decreases expression EXP Zinc Sulfate results in decreased expression of THBD mRNA CTD PMID:17074742 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 increases expression EXP Zinc Sulfate results in increased expression of TIMP3 mRNA CTD PMID:17074742 NCBI chr 7:23,543,125...23,594,170
Ensembl chr 7:23,544,215...23,594,133
JBrowse link
G Tll1 tolloid-like 1 decreases expression ISO Zinc Sulfate results in decreased expression of TLL1 mRNA CTD PMID:16330358 NCBI chr16:27,399,467...27,597,240
Ensembl chr16:27,399,467...27,597,240
JBrowse link
G Tll2 tolloid-like 2 increases expression ISO Zinc Sulfate results in increased expression of TLL2 mRNA CTD PMID:16330358 NCBI chr 1:260,348,905...260,460,791
Ensembl chr 1:260,348,905...260,460,791
JBrowse link
G Tmem184c transmembrane protein 184C decreases expression ISO Zinc Sulfate results in decreased expression of TMEM184C mRNA CTD PMID:12756304 NCBI chr19:34,041,128...34,057,165
Ensembl chr19:34,041,219...34,057,159
JBrowse link
G Tnf tumor necrosis factor multiple interactions
affects expression
ISO
EXP
[Disulfiram co-treated with Zinc Sulfate] inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; TNF protein promotes the reaction [Zinc Sulfate results in increased expression of MT1G mRNA]; Zinc Sulfate inhibits the reaction [IFNG protein results in increased secretion of TNF protein]; Zinc Sulfate inhibits the reaction [Nickel results in increased secretion of TNF protein]; Zinc Sulfate inhibits the reaction [TNF protein affects the localization of RELA protein]; Zinc Sulfate inhibits the reaction [TNF protein results in increased activity of RELA protein]; Zinc Sulfate inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; Zinc Sulfate inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; Zinc Sulfate inhibits the reaction [TNF protein results in increased expression of IL1A mRNA]; Zinc Sulfate inhibits the reaction [TNF protein results in increased expression of IL1B mRNA]; Zinc Sulfate inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; Zinc Sulfate inhibits the reaction [TNF protein results in increased secretion of CXCL8 protein]; Zinc Sulfate inhibits the reaction [TNF protein results in increased secretion of ICAM1 protein]; Zinc Sulfate inhibits the reaction [TNF protein results in increased secretion of IL6 protein]; Zinc Sulfate inhibits the reaction [TNF protein results in increased secretion of IL6ST protein]; Zinc Sulfate inhibits the reaction [TNF protein results in increased secretion of MMP9 protein]; Zinc Sulfate inhibits the reaction [TNF protein results in increased secretion of VEGFA protein]
Zinc Sulfate affects the expression of TNF mRNA
Zinc Sulfate inhibits the reaction [Carmustine results in increased expression of TNF protein]
Zinc Sulfate inhibits the reaction [Ethanol results in increased expression of TNF protein]
CTD PMID:7747530, PMID:15920153, PMID:16606632, PMID:20046642, PMID:20385217, PMID:22722935, PMID:32712770 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions
increases expression
ISO [CSF1 protein co-treated with TNFSF11 protein co-treated with Cryptoxanthins co-treated with Zinc Sulfate] results in decreased expression of ACP5 mRNA; [CSF1 protein co-treated with TNFSF11 protein co-treated with Cryptoxanthins] promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]; [CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] promotes the reaction [Cryptoxanthins results in increased expression of CASP3 mRNA]; [CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] results in decreased expression of CTSK mRNA; [CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] results in decreased expression of NFATC1 mRNA; [Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in decreased expression of CTSK mRNA; [Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in decreased expression of NFATC1 mRNA; [Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 mRNA; [Zinc Sulfate co-treated with Genistein co-treated with CSF1 protein co-treated with TNFSF11 protein] results in decreased expression of ACP5 mRNA; Cryptoxanthins promotes the reaction [[Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in decreased expression of CTSK mRNA]; Cryptoxanthins promotes the reaction [[Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in decreased expression of NFATC1 mRNA]; Cycloheximide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Cryptoxanthins] promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] promotes the reaction [Cryptoxanthins results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [Genistein promotes the reaction [[Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [Zinc Sulfate results in increased expression of TNFSF11 mRNA]; Dichlororibofuranosylbenzimidazole inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Cryptoxanthins] promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] promotes the reaction [Cryptoxanthins results in increased expression of CASP3 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Genistein promotes the reaction [[Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 mRNA]]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Zinc Sulfate results in increased expression of TNFSF11 mRNA]; Genistein promotes the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] results in decreased expression of CTSK mRNA]; Genistein promotes the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] results in decreased expression of NFATC1 mRNA]; Genistein promotes the reaction [[Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 mRNA]; Zinc Sulfate promotes the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Genistein] results in decreased expression of CTSK mRNA] CTD PMID:17295206, PMID:18327666, PMID:18636177 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
JBrowse link
G Tns3 tensin 3 increases expression ISO Zinc Sulfate results in increased expression of TNS3 mRNA CTD PMID:12756304 NCBI chr14:88,673,922...88,907,874
Ensembl chr14:88,673,881...88,886,198
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [Acetylcysteine co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]; [Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein; Acetylcysteine inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]; Zinc Sulfate inhibits the reaction [prolinedithiocarbamate results in increased phosphorylation of TP53 protein]; Zinc Sulfate results in increased phosphorylation of and results in increased expression of TP53 protein CTD PMID:15001399, PMID:18951928 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tpm4 tropomyosin 4 decreases expression EXP Zinc Sulfate results in decreased expression of TPM4 mRNA CTD PMID:17074742 NCBI chr16:19,385,810...19,399,851
Ensembl chr16:19,385,736...19,399,903
JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 decreases expression ISO Zinc Sulfate results in decreased expression of TREM1 mRNA CTD PMID:12756304 NCBI chr 9:14,727,887...14,743,371
Ensembl chr 9:14,727,976...14,809,447
JBrowse link
G Trim31 tripartite motif-containing 31 decreases expression ISO Zinc Sulfate results in decreased expression of TRIM31 mRNA CTD PMID:16330358 NCBI chr20:2,146,245...2,159,875
Ensembl chr20:2,146,257...2,159,631
JBrowse link
G Trpm5 transient receptor potential cation channel, subfamily M, member 5 affects response to substance ISO TRPM5 protein affects the susceptibility to Zinc Sulfate CTD PMID:19244541 NCBI chr 1:216,256,653...216,281,504
Ensembl chr 1:216,257,820...216,274,930
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 increases activity ISO Zinc Sulfate results in increased activity of TRPV1 protein CTD PMID:17567713 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 increases expression ISO Zinc Sulfate results in increased expression of TSC22D1 mRNA CTD PMID:12756304 NCBI chr15:58,554,358...58,658,156
Ensembl chr15:58,554,374...58,658,153
JBrowse link
G Tsr1 TSR1, ribosome maturation factor increases expression ISO Zinc Sulfate results in increased expression of TSR1 mRNA CTD PMID:19013360 NCBI chr10:61,746,070...61,757,518
Ensembl chr10:61,746,059...61,757,518
JBrowse link
G Tubb4a tubulin, beta 4A class IVa affects expression ISO Zinc Sulfate affects the expression of TUBB4A protein CTD PMID:25162517 NCBI chr 9:9,961,020...9,968,420
Ensembl chr 9:9,961,021...9,968,486
JBrowse link
G Txndc12 thioredoxin domain containing 12 decreases expression ISO Zinc Sulfate results in decreased expression of TXNDC12 mRNA CTD PMID:19013360 NCBI chr 5:128,450,830...128,475,858
Ensembl chr 5:128,450,680...128,475,864
JBrowse link
G Ube2g2 ubiquitin-conjugating enzyme E2G 2 decreases expression ISO Zinc Sulfate results in decreased expression of UBE2G2 mRNA CTD PMID:12756304 NCBI chr20:11,700,089...11,721,823
Ensembl chr20:11,700,089...11,721,838
JBrowse link
G Ube2i ubiquitin-conjugating enzyme E2I increases expression ISO Zinc Sulfate results in increased expression of UBE2I mRNA CTD PMID:12756304 NCBI chr10:14,618,615...14,639,274
Ensembl chr10:14,620,531...14,630,151
JBrowse link
G Ucp3 uncoupling protein 3 increases expression EXP Zinc Sulfate results in increased expression of UCP3 mRNA CTD PMID:17074742 NCBI chr 1:165,482,912...165,495,895
Ensembl chr 1:165,482,155...165,496,206
JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase increases expression ISO Zinc Sulfate results in increased expression of UGCG mRNA CTD PMID:12756304 NCBI chr 5:76,376,722...76,419,564
Ensembl chr 5:76,386,836...76,419,560
JBrowse link
G Unc119 unc-119 lipid binding chaperone increases expression ISO Zinc Sulfate results in increased expression of UNC119 mRNA CTD PMID:15226459 NCBI chr10:65,606,919...65,612,324
Ensembl chr10:65,606,898...65,612,324
JBrowse link
G Usp44 ubiquitin specific peptidase 44 decreases expression ISO Zinc Sulfate results in decreased expression of USP44 mRNA CTD PMID:16330358 NCBI chr 7:34,714,293...34,759,352
Ensembl chr 7:34,744,483...34,759,206
JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions EXP Zinc Sulfate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of VDAC1 mRNA]; Zinc Sulfate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of VDAC1 protein] CTD PMID:21605504 NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826
JBrowse link
G Vdac2 voltage-dependent anion channel 2 multiple interactions EXP Zinc Sulfate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of VDAC2 mRNA]; Zinc Sulfate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of VDAC2 protein] CTD PMID:21605504 NCBI chr15:2,634,622...2,648,548
Ensembl chr15:2,634,624...2,648,551
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO Zinc Sulfate inhibits the reaction [TNF protein results in increased secretion of VEGFA protein] CTD PMID:16606632 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vegfc vascular endothelial growth factor C decreases expression EXP Zinc Sulfate results in decreased expression of VEGFC mRNA CTD PMID:17074742 NCBI chr16:40,440,371...40,555,178
Ensembl chr16:40,440,207...40,555,576
JBrowse link
G Vps33b VPS33B, late endosome and lysosome associated increases expression ISO Zinc Sulfate results in increased expression of VPS33B mRNA CTD PMID:12756304 NCBI chr 1:142,060,955...142,083,955
Ensembl chr 1:142,060,955...142,083,953
JBrowse link
G Wdr13 WD repeat domain 13 decreases expression ISO Zinc Sulfate results in decreased expression of WDR13 mRNA CTD PMID:12756304 NCBI chr  X:15,112,663...15,123,825
Ensembl chr  X:15,113,878...15,122,146
JBrowse link
G Wdr46 WD repeat domain 46 decreases expression ISO Zinc Sulfate results in decreased expression of WDR46 mRNA CTD PMID:15226459 NCBI chr20:5,447,860...5,455,632
Ensembl chr20:5,447,860...5,455,632
JBrowse link
G Wipf2 WAS/WASL interacting protein family, member 2 increases expression ISO Zinc Sulfate results in increased expression of WIPF2 mRNA CTD PMID:12756304 NCBI chr10:86,776,367...86,813,046
Ensembl chr10:86,795,787...86,812,325
JBrowse link
G Wnk2 WNK lysine deficient protein kinase 2 decreases expression ISO Zinc Sulfate results in decreased expression of WNK2 mRNA CTD PMID:16330358 NCBI chr17:15,923,508...16,032,271
Ensembl chr17:15,924,048...16,032,420
JBrowse link
G Xdh xanthine dehydrogenase increases expression EXP Zinc Sulfate results in increased expression of XDH mRNA CTD PMID:17074742 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
G Zdhhc14 zinc finger DHHC-type palmitoyltransferase 14 decreases expression ISO Zinc Sulfate results in decreased expression of ZDHHC14 mRNA CTD PMID:12756304 NCBI chr 1:46,378,807...46,658,527
Ensembl chr 1:46,378,807...46,649,292
JBrowse link
G Zfp141 zinc finger protein 141 increases expression ISO Zinc Sulfate results in increased expression of ZNF816 mRNA CTD PMID:12756304 NCBI chr 1:98,168,457...98,201,189 JBrowse link
G Zfp36 zinc finger protein 36 increases expression ISO Zinc Sulfate results in increased expression of ZFP36 mRNA CTD PMID:12756304 NCBI chr 1:85,380,088...85,382,565
Ensembl chr 1:85,380,088...85,382,569
JBrowse link
G Zfp64 zinc finger protein 64 increases expression ISO Zinc Sulfate results in increased expression of ZFP64 mRNA CTD PMID:12756304 NCBI chr 3:165,713,070...165,741,932
Ensembl chr 3:165,713,020...165,741,967
JBrowse link
G Zfp764 zinc finger protein 764 increases expression ISO Zinc Sulfate results in increased expression of ZNF764 mRNA CTD PMID:12756304 NCBI chr 1:198,834,995...198,839,251
Ensembl chr 1:198,834,989...198,839,228
JBrowse link
ziram term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of ABCC2 mRNA CTD PMID:32745781 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of ABCC3 mRNA CTD PMID:32745781 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of ACOX1 mRNA CTD PMID:32736067 NCBI chr10:104,724,534...104,748,003
Ensembl chr10:104,722,958...104,748,050
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation EXP Ziram results in decreased phosphorylation of AKT1 protein CTD PMID:30422632 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Amh anti-Mullerian hormone decreases expression
increases expression
EXP Ziram results in decreased expression of AMH mRNA; Ziram results in decreased expression of AMH protein
Ziram results in increased expression of AMH mRNA
CTD PMID:29627606, PMID:30422632 NCBI chr 7:11,775,155...11,777,503
Ensembl chr 7:11,775,155...11,777,503
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP Ziram results in increased expression of BAX protein CTD PMID:28973382 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP Ziram results in decreased expression of BCL2 protein CTD PMID:28973382 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp1 caspase 1 multiple interactions ISO Acetylcysteine inhibits the reaction [Ziram results in decreased expression of and results in increased degradation of CASP1 protein]; Dithiothreitol inhibits the reaction [Ziram results in decreased expression of and results in increased degradation of CASP1 protein]; Edetic Acid inhibits the reaction [Ziram results in decreased expression of and results in increased degradation of CASP1 protein]; Mercaptoethanol inhibits the reaction [Ziram results in decreased expression of and results in increased degradation of CASP1 protein]; Ziram results in decreased expression of and results in increased degradation of CASP1 protein CTD PMID:25929180 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp3 caspase 3 increases activity ISO Ziram results in increased activity of CASP3 protein CTD PMID:20842346, PMID:22159898 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases activity ISO Ziram results in increased activity of CASP8 protein CTD PMID:22159898 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases activity ISO Ziram results in increased activity of CASP9 protein CTD PMID:22159898 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase increases expression ISO Ziram results in increased expression of CAT mRNA CTD PMID:32712770 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases secretion
ISO Ziram inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]
Ziram results in decreased secretion of CCL2 protein
CTD PMID:32712770 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccnd3 cyclin D3 decreases expression EXP Ziram results in decreased expression of CCND3 mRNA CTD PMID:28973382 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression
decreases expression
ISO Ziram results in increased expression of CCR2 mRNA
Ziram results in decreased expression of CCR2 protein
CTD PMID:32712770
G Cd163 CD163 molecule decreases expression ISO Ziram results in decreased expression of CD163 mRNA; Ziram results in decreased expression of CD163 protein CTD PMID:32712770 NCBI chr 4:156,752,063...156,785,467
Ensembl chr 4:156,752,082...156,785,467
JBrowse link
G Cd209 CD209 molecule increases expression ISO Ziram results in increased expression of CD209 mRNA; Ziram results in increased expression of CD209 protein CTD PMID:32712770 NCBI chr12:2,406,879...2,413,324
Ensembl chr12:2,406,879...2,413,324
JBrowse link
G Cd36 CD36 molecule multiple interactions
decreases expression
ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CD36 mRNA
Ziram results in decreased expression of CD36 mRNA; Ziram results in decreased expression of CD36 protein
CTD PMID:32712770, PMID:32736067 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Clec7a C-type lectin domain containing 7A decreases expression ISO Ziram results in decreased expression of CLEC7A protein CTD PMID:32712770 NCBI chr 4:163,216,152...163,227,367
Ensembl chr 4:163,216,163...163,227,334
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CPT1A mRNA CTD PMID:32736067 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Cycs cytochrome c, somatic affects localization ISO Ziram affects the localization of CYCS protein CTD PMID:20842346, PMID:22159898 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases activity
affects expression
decreases expression
EXP Ziram results in decreased activity of CYP11A1 protein
Ziram affects the expression of CYP11A1 mRNA; Ziram affects the expression of CYP11A1 protein
Ziram results in decreased expression of CYP11A1 mRNA; Ziram results in decreased expression of CYP11A1 protein
CTD PMID:28973382, PMID:29627606 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression
affects expression
decreases activity
EXP Ziram results in decreased expression of CYP17A1 mRNA; Ziram results in decreased expression of CYP17A1 protein
Ziram affects the expression of CYP17A1 mRNA; Ziram affects the expression of CYP17A1 protein
Ziram results in decreased activity of CYP17A1 protein
CTD PMID:28973382, PMID:29627606, PMID:30422632 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of CYP2B10 mRNA; [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CYP2B10 mRNA CTD PMID:32736067, PMID:32745781 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of CYP2B9 mRNA CTD PMID:32745781 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CYP2C55 mRNA CTD PMID:32736067 NCBI chr 1:258,074,797...258,139,176
Ensembl chr 1:258,074,860...258,139,176
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of CYP2C29 mRNA CTD PMID:32745781 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Dhh desert hedgehog signaling molecule decreases expression EXP Ziram results in decreased expression of DHH mRNA; Ziram results in decreased expression of DHH protein CTD PMID:29627606 NCBI chr 7:140,575,288...140,580,783
Ensembl chr 7:140,575,288...140,580,783
JBrowse link
G Dio1 iodothyronine deiodinase 1 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of DIO1 mRNA CTD PMID:32745781 NCBI chr 5:126,894,837...126,911,532
Ensembl chr 5:126,895,286...126,911,520
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of ECI1 mRNA CTD PMID:32736067 NCBI chr10:13,797,573...13,810,918
Ensembl chr10:13,797,562...13,810,913
JBrowse link
G Fcgr3a Fc fragment of IgG receptor IIIa decreases expression ISO Ziram results in decreased expression of FCGR3A protein CTD PMID:18670896 NCBI chr13:89,385,775...89,396,047
Ensembl chr13:89,385,859...89,396,051
JBrowse link
G Fshb follicle stimulating hormone subunit beta decreases expression EXP Ziram results in decreased expression of FSHB mRNA; Ziram results in decreased expression of FSHB protein CTD PMID:28973382, PMID:30422632 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G Fshr follicle stimulating hormone receptor decreases expression EXP Ziram results in decreased expression of FSHR mRNA; Ziram results in decreased expression of FSHR protein CTD PMID:29627606 NCBI chr 6:12,796,383...12,997,817
Ensembl chr 6:12,796,383...12,997,817
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of GFAP protein CTD PMID:32736067 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Gzma granzyme A decreases expression ISO Ziram results in decreased expression of GZMA protein CTD PMID:22038140 NCBI chr 2:44,968,846...44,981,436
Ensembl chr 2:44,968,765...44,981,458
JBrowse link
G Gzmb granzyme B decreases expression ISO Ziram results in decreased expression of GZMB protein CTD PMID:21859362, PMID:22038140 NCBI chr15:35,413,862...35,417,293
Ensembl chr15:35,413,793...35,417,316
JBrowse link
G Gzmk granzyme K decreases expression ISO Ziram results in decreased expression of GZMK protein CTD PMID:22038140 NCBI chr 2:45,069,136...45,077,154
Ensembl chr 2:45,068,967...45,077,219
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of HMGCS2 mRNA CTD PMID:32745781 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO Trientine inhibits the reaction [Ziram results in increased expression of HMOX1 protein]
Ziram results in increased expression of HMOX1 mRNA; Ziram results in increased expression of HMOX1 protein
CTD PMID:25714994, PMID:32712770 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 multiple interactions
decreases expression
decreases activity
EXP Ziram inhibits the reaction [[HSD11B1 protein results in increased reduction of 11-dehydrocorticosterone] which results in increased chemical synthesis of Corticosterone]; Ziram inhibits the reaction [HSD11B1 protein results in increased oxidation of NADP]; Ziram inhibits the reaction [HSD11B1 protein results in increased reduction of 11-dehydrocorticosterone]
Ziram results in decreased expression of HSD11B1 mRNA; Ziram results in decreased expression of HSD11B1 protein
Ziram results in decreased activity of HSD11B1 protein
CTD PMID:26859423, PMID:28973382 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 multiple interactions
decreases activity
ISO
EXP
Dithiothreitol inhibits the reaction [Ziram results in decreased activity of HSD11B2 protein]; Ziram inhibits the reaction [[HSD11B2 protein results in increased oxidation of Hydrocortisone] which results in increased chemical synthesis of Cortisone]; Ziram inhibits the reaction [HSD11B2 protein results in increased oxidation of Hydrocortisone]; Ziram inhibits the reaction [HSD11B2 protein results in increased reduction of NAD]
Dithiothreitol inhibits the reaction [Ziram results in decreased activity of HSD11B2 protein]; Ziram inhibits the reaction [[HSD11B2 protein results in increased oxidation of Corticosterone] which results in increased chemical synthesis of 11-dehydrocorticosterone]; Ziram inhibits the reaction [HSD11B2 protein results in increased oxidation of Corticosterone]; Ziram inhibits the reaction [HSD11B2 protein results in increased reduction of NAD]
CTD PMID:26859423 NCBI chr19:37,476,083...37,481,326
Ensembl chr19:37,476,095...37,481,307
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 decreases activity
decreases expression
EXP Ziram results in decreased activity of HSD17B3 protein
Ziram results in decreased expression of HSD17B3 mRNA; Ziram results in decreased expression of HSD17B3 protein
CTD PMID:28973382, PMID:29627606, PMID:30422632 NCBI chr17:1,579,319...1,610,745
Ensembl chr17:1,579,319...1,610,745
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases activity
decreases expression
EXP Ziram results in decreased activity of HSD3B1 protein
Ziram results in decreased expression of HSD3B1 mRNA; Ziram results in decreased expression of HSD3B1 protein
CTD PMID:28973382
G Ifnb1 interferon beta 1 multiple interactions ISO Ziram inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA] CTD PMID:18177342 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Ifng interferon gamma increases expression ISO Ziram results in increased expression of IFNG protein CTD PMID:12062936 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Ziram inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]
Ziram inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
CTD PMID:25929180, PMID:32712770 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il4 interleukin 4 increases expression ISO Ziram results in increased expression of IL4 protein CTD PMID:12062936 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Ziram inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:32712770 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Insl3 insulin-like 3 decreases expression EXP Ziram results in decreased expression of INSL3 mRNA; Ziram results in decreased expression of INSL3 protein CTD PMID:29627606 NCBI chr16:20,120,753...20,122,702
Ensembl chr16:20,121,352...20,122,696
JBrowse link
G Itgam integrin subunit alpha M increases expression ISO Ziram results in increased expression of ITGAM mRNA; Ziram results in increased expression of ITGAM protein CTD PMID:32712770 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Lep leptin multiple interactions EXP [2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in increased expression of LEP protein CTD PMID:29321614 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lepr leptin receptor multiple interactions EXP [2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in decreased expression of LEPR mRNA CTD PMID:29321614 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor decreases expression
affects expression
EXP Ziram results in decreased expression of LHCGR mRNA; Ziram results in decreased expression of LHCGR protein
Ziram affects the expression of LHCGR mRNA; Ziram affects the expression of LHCGR protein
CTD PMID:28973382, PMID:29627606, PMID:30422632 NCBI chr 6:12,493,182...12,554,482
Ensembl chr 6:12,493,943...12,554,439
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases activity ISO Ziram results in increased activity of MAPK1 protein CTD PMID:21859362 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases activity ISO Ziram results in increased activity of MAPK3 protein CTD PMID:21859362 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mrc1 mannose receptor, C type 1 decreases expression ISO Ziram results in decreased expression of MRC1 protein CTD PMID:32712770 NCBI chr17:81,352,700...81,433,743
Ensembl chr17:81,352,700...81,433,743
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 affects expression ISO Ziram affects the expression of NFE2L2 mRNA CTD PMID:32712770 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Ziram inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein] CTD PMID:17015962 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 decreases expression ISO Ziram results in decreased expression of NLRP3 protein CTD PMID:25929180 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Nmb neuromedin B multiple interactions EXP [2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in decreased expression of NMB mRNA CTD PMID:29321614 NCBI chr 1:142,721,263...142,724,646
Ensembl chr 1:142,721,002...142,724,511
JBrowse link
G Nmbr neuromedin B receptor multiple interactions EXP [2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in increased expression of NMBR mRNA CTD PMID:29321614 NCBI chr 1:8,933,744...8,945,850
Ensembl chr 1:8,933,831...8,944,987
JBrowse link
G Npy1r neuropeptide Y receptor Y1 multiple interactions EXP [2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in increased expression of NPY1R mRNA CTD PMID:29321614 NCBI chr16:24,779,480...24,789,131
Ensembl chr16:24,779,477...24,788,740
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO NR1I3 protein affects the susceptibility to [2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with Thiophanate co-treated with thiacloprid co-treated with Ziram] CTD PMID:29950287 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 decreases expression
affects expression
EXP Ziram results in decreased expression of NR5A1 mRNA; Ziram results in decreased expression of NR5A1 protein
Ziram affects the expression of NR5A1 mRNA; Ziram affects the expression of NR5A1 protein
CTD PMID:28973382, PMID:29627606 NCBI chr 3:22,998,900...23,020,441
Ensembl chr 3:22,999,616...23,020,441
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of PDGFRB protein CTD PMID:32736067 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects expression ISO Ziram affects the expression of PPARG mRNA CTD PMID:32712770 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha decreases expression EXP Ziram results in decreased expression of PPARGC1A protein CTD PMID:30422632 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Prf1 perforin 1 decreases expression ISO Ziram results in decreased expression of PRF1 protein CTD PMID:21859362, PMID:22038140 NCBI chr20:30,915,294...30,920,804
Ensembl chr20:30,915,213...30,921,382
JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression
affects expression
EXP Ziram results in decreased expression of SCARB1 mRNA; Ziram results in decreased expression of SCARB1 protein
Ziram affects the expression of SCARB1 mRNA; Ziram affects the expression of SCARB1 protein
CTD PMID:28973382, PMID:29627606, PMID:30422632 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SERPINE1 mRNA CTD PMID:32745781 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Sirt1 sirtuin 1 decreases expression EXP Ziram results in decreased expression of SIRT1 protein CTD PMID:30422632 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc16a2 solute carrier family 16 member 2 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SLC16A2 mRNA CTD PMID:32745781 NCBI chr  X:74,578,600...74,706,068
Ensembl chr  X:74,577,131...74,706,214
JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO Ziram inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] CTD PMID:31652400 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Snca synuclein alpha increases expression EXP Ziram results in increased expression of SNCA protein CTD PMID:18818210 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Sod2 superoxide dismutase 2 increases expression ISO Ziram results in increased expression of SOD2 mRNA CTD PMID:32712770 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sox9 SRY-box transcription factor 9 decreases expression EXP Ziram results in decreased expression of SOX9 mRNA; Ziram results in decreased expression of SOX9 protein CTD PMID:29627606 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases expression EXP Ziram results in decreased expression of SRD5A1 mRNA CTD PMID:30422632 NCBI chr 1:36,320,504...36,354,694
Ensembl chr 1:36,320,461...36,354,756
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression
affects expression
EXP Ziram results in decreased expression of STAR mRNA; Ziram results in decreased expression of STAR protein
Ziram affects the expression of STAR mRNA; Ziram affects the expression of STAR protein
CTD PMID:28973382, PMID:29627606, PMID:30422632 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SULT1B1 mRNA CTD PMID:32745781 NCBI chr14:22,142,412...22,155,246
Ensembl chr14:22,142,364...22,155,231
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases activity
multiple interactions
ISO Ziram results in decreased activity of TGFB1 protein
Ziram inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]
CTD PMID:31652400 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Thrsp thyroid hormone responsive multiple interactions ISO [2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of THRSP mRNA; [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in decreased expression of THRSP mRNA; Dietary Fats inhibits the reaction [[2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of THRSP mRNA] CTD PMID:32745781 NCBI chr 1:162,381,251...162,385,575
Ensembl chr 1:162,381,253...162,385,575
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Ziram inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:16112155, PMID:32712770 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tpo thyroid peroxidase decreases activity ISO Ziram results in decreased activity of TPO protein CTD PMID:9248629 NCBI chr 6:49,020,918...49,089,855
Ensembl chr 6:49,021,044...49,089,855
JBrowse link
G Tspo translocator protein decreases expression EXP Ziram results in decreased expression of TSPO mRNA CTD PMID:28973382 NCBI chr 7:124,460,358...124,470,610
Ensembl chr 7:124,460,358...124,470,609
JBrowse link
G Uba1 ubiquitin-like modifier activating enzyme 1 decreases activity
multiple interactions
ISO Ziram results in decreased activity of UBA1 protein
Trientine inhibits the reaction [Ziram results in decreased activity of and results in decreased ubiquitination of UBA1 protein]; Ziram results in decreased activity of and results in decreased ubiquitination of UBA1 protein
CTD PMID:18818210, PMID:25714994 NCBI chr  X:1,723,135...1,745,147
Ensembl chr  X:1,723,174...1,741,701
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    chemical entity 19787
      molecular entity 19784
        ion 15918
          monoatomic ion 15153
            zinc ion 479
              zinc cation + 478
              zincide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  metal atom 17263
                    transition element atom 16711
                      transition element molecular entity 16398
                        d-block molecular entity 16390
                          zinc group molecular entity 9967
                            zinc molecular entity 2695
                              elemental zinc 2392
                                zinc ion 479
                                  zinc cation + 478
                                  zincide 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.