CHEBI ONTOLOGY - ANNOTATIONS |
|
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
|
Term: | vinca alkaloid |
|
Accession: | CHEBI:27288
|
browse the term
|
Definition: | A group of indole-indoline dimers which are alkaloids obtained from the Vinca genus of plants, together with semi-synthetic and fully synthetic analogues. |
Synonyms: | related_synonym: | vinca alkaloids; vincaleukoblastines |
| xref: | Wikipedia:Vinca_alkaloid |
|
|
|
G |
Abca2 |
ATP binding cassette subfamily A member 2 |
decreases response to substance increases expression |
ISO |
ABCA2 mRNA results in decreased susceptibility to Vinblastine Vinblastine results in increased expression of ABCA2 mRNA |
CTD |
PMID:16928819 |
|
NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809
|
|
G |
Abca3 |
ATP binding cassette subfamily A member 3 |
decreases response to substance increases expression |
ISO |
ABCA3 mRNA results in decreased susceptibility to Vinblastine Vinblastine results in increased expression of ABCA3 mRNA |
CTD |
PMID:16928819 |
|
NCBI chr10:13,723,365...13,780,558
Ensembl chr10:13,723,405...13,779,963
|
|
G |
Abcb11 |
ATP binding cassette subfamily B member 11 |
decreases uptake decreases activity multiple interactions increases export |
ISO |
ABCB11 protein results in decreased uptake of Vinblastine Vinblastine results in decreased activity of ABCB11 protein Vinblastine inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid] ABCB11 protein results in increased export of Vinblastine |
CTD |
PMID:10617675 PMID:24014644 |
|
NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
|
|
G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
decreases response to substance increases secretion increases activity increases expression affects binding multiple interactions affects uptake increases transport |
ISO EXP |
ABCB1 protein results in decreased susceptibility to Vinblastine ABCB1A protein results in increased secretion of Vinblastine Vinblastine results in increased activity of ABCB1 protein mutant form Vinblastine results in increased expression of ABCB1 protein Vinblastine binds to ABCB1 protein [Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]] which results in decreased susceptibility to Vinblastine; [Elacridar binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Vinblastine; [sodium arsenite results in increased expression of ABCB1 protein] which results in decreased susceptibility to Vinblastine; [Vinblastine results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; Amiodarone inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]; Clotrimazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; cnidiadin inhibits the reaction [ABCB1 protein results in increased export of Vinblastine]; Curcumin analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]; Curcumin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]; Cyclosporine inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Diazinon affects the reaction [ABCB1 protein results in increased transport of Vinblastine]; Erythromycin inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Ketoconazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Miconazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; NR1I2 protein promotes the reaction [Vinblastine results in increased expression of ABCB1 protein]; Reserpine inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Sesquiterpenes analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]; Troleandomycin inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Verapamil inhibits the reaction [ABCB1 protein affects the uptake of Vinblastine]; Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]; Vinblastine inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form] |
CTD |
PMID:1967174 PMID:8917702 PMID:9148857 PMID:11355955 PMID:11455017 PMID:12235267 PMID:12708479 PMID:12711602 PMID:15466210 PMID:15640379 PMID:15725475 PMID:15824923 PMID:16221533 PMID:17284363 PMID:20041327 PMID:23976943 PMID:26689174 |
|
NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
|
|
G |
Abcb1b |
ATP-binding cassette, subfamily B (MDR/TAP), member 1B |
increases secretion |
EXP |
ABCB1B protein results in increased secretion of Vinblastine |
CTD |
PMID:12235267 |
|
NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
|
|
G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
affects response to substance decreases response to substance |
ISO EXP |
ABCC1 protein affects the susceptibility to Vinblastine ABCC1 protein results in decreased susceptibility to Vinblastine |
CTD |
PMID:9334814 PMID:11455017 PMID:16156793 |
|
NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
|
|
G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
affects transport decreases response to substance multiple interactions |
ISO EXP |
ABCC2 protein affects the transport of Vinblastine ABCC2 protein results in decreased susceptibility to Vinblastine [isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate results in decreased activity of ABCC2 protein] which results in increased uptake of Vinblastine; [verlukast results in decreased activity of ABCC2 protein] which results in increased uptake of Vinblastine; Probenecid promotes the reaction [ABCC2 protein affects the transport of Vinblastine] |
CTD |
PMID:9525973 PMID:11455017 PMID:15849751 PMID:25844889 |
|
NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
|
|
G |
Ablim1 |
actin-binding LIM protein 1 |
affects response to substance |
ISO |
ABLIM1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 1:277,853,877...278,043,096
|
|
G |
Acat2 |
acetyl-CoA acetyltransferase 2 |
affects response to substance |
ISO |
ACAT2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653
|
|
G |
Acot13 |
acyl-CoA thioesterase 13 |
affects response to substance |
ISO |
ACOT13 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr17:42,241,141...42,253,611
Ensembl chr17:42,241,159...42,253,649
|
|
G |
Acp1 |
acid phosphatase 1 |
affects response to substance |
ISO |
ACP1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 6:49,836,064...49,851,714
Ensembl chr 6:49,836,075...49,851,714
|
|
G |
Add3 |
adducin 3 |
affects response to substance |
ISO |
ADD3 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 1:273,854,195...273,961,982
Ensembl chr 1:273,854,248...273,961,982
|
|
G |
Aif1 |
allograft inflammatory factor 1 |
decreases expression |
EXP |
Vinblastine results in decreased expression of AIF1 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
|
|
G |
Ak1 |
adenylate kinase 1 |
decreases expression |
EXP |
Vinblastine results in decreased expression of AK1 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 3:11,652,143...11,659,135
|
|
G |
Aox1 |
aldehyde oxidase 1 |
affects response to substance |
ISO |
AOX1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 9:64,929,682...65,007,872
Ensembl chr 9:64,929,721...65,007,870
|
|
G |
Apln |
apelin |
decreases expression |
EXP |
Vinblastine results in decreased expression of APLN mRNA |
CTD |
PMID:20624997 |
|
NCBI chr X:134,856,719...134,866,210
Ensembl chr X:134,856,726...134,866,210
|
|
G |
Atp5me |
ATP synthase membrane subunit e |
affects response to substance |
ISO |
ATP5ME protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr14:2,325,308...2,326,436
Ensembl chr14:2,325,308...2,326,436
|
|
G |
Atp5mf |
ATP synthase membrane subunit f |
affects response to substance |
ISO |
ATP5MF protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr12:11,191,799...11,198,369
Ensembl chr12:11,191,812...11,198,369
|
|
G |
Aurkb |
aurora kinase B |
affects response to substance |
ISO |
AURKB protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
|
|
G |
Axl |
Axl receptor tyrosine kinase |
affects response to substance |
ISO |
AXL protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761
|
|
G |
Birc2 |
baculoviral IAP repeat-containing 2 |
affects response to substance |
ISO |
BIRC2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
|
|
G |
Birc3 |
baculoviral IAP repeat-containing 3 |
affects response to substance |
ISO |
BIRC3 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
|
|
G |
Birc7 |
baculoviral IAP repeat-containing 7 |
decreases response to substance |
ISO |
BIRC7 protein results in decreased susceptibility to Vinblastine |
CTD |
PMID:17437058 |
|
NCBI chr 3:176,438,335...176,443,864
Ensembl chr 3:176,439,199...176,443,195
|
|
G |
Bub1 |
BUB1 mitotic checkpoint serine/threonine kinase |
affects response to substance |
ISO |
BUB1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910
|
|
G |
Casp3 |
caspase 3 |
increases cleavage multiple interactions |
EXP ISO |
Vinblastine results in increased cleavage of CASP3 protein CD40LG protein inhibits the reaction [Vinblastine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]; Vinblastine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein] |
CTD |
PMID:16545138 PMID:20624997 |
|
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
|
|
G |
Cat |
catalase |
affects response to substance |
ISO |
CAT protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
|
|
G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases expression |
EXP |
Vinblastine results in increased expression of CCL2 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
|
|
G |
Ccn2 |
cellular communication network factor 2 |
affects response to substance |
ISO |
CCN2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
|
|
G |
Ccnb1 |
cyclin B1 |
affects response to substance increases response to substance |
ISO |
CCNB1 protein affects the susceptibility to Vinblastine CCNB1 protein results in increased susceptibility to Vinblastine |
CTD |
PMID:16217747 PMID:16849574 |
|
NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
|
|
G |
Ccnb2 |
cyclin B2 |
affects response to substance |
ISO |
CCNB2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 8:76,847,972...76,861,165
|
|
G |
Cd14 |
CD14 molecule |
increases expression |
EXP |
Vinblastine results in increased expression of CD14 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
|
|
G |
Cd40lg |
CD40 ligand |
decreases response to substance multiple interactions |
ISO |
CD40LG protein results in decreased susceptibility to Vinblastine CD40LG protein inhibits the reaction [Vinblastine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]] |
CTD |
PMID:16545138 |
|
NCBI chr X:159,703,703...159,714,886
Ensembl chr X:159,703,578...159,716,562
|
|
G |
Cd44 |
CD44 molecule (Indian blood group) |
increases expression |
EXP |
Vinblastine results in increased expression of CD44 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
|
|
G |
Cdca8 |
cell division cycle associated 8 |
affects response to substance |
ISO |
CDCA8 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 5:142,911,310...142,933,536
Ensembl chr 5:142,911,305...142,933,526
|
|
G |
Cdk1 |
cyclin-dependent kinase 1 |
affects response to substance |
ISO |
CDK1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
|
|
G |
Cdk2 |
cyclin dependent kinase 2 |
affects response to substance |
ISO |
CDK2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
|
|
G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression |
EXP |
Vinblastine results in increased expression of CDKN1A mRNA |
CTD |
PMID:20624997 |
|
NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
|
|
G |
Cdkn2c |
cyclin-dependent kinase inhibitor 2C |
affects response to substance |
ISO |
CDKN2C protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 5:129,347,731...129,352,886
Ensembl chr 5:129,347,732...129,352,886
|
|
G |
Cdkn3 |
cyclin-dependent kinase inhibitor 3 |
decreases expression |
EXP |
Vinblastine results in decreased expression of CDKN3 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr15:23,553,171...23,564,538
Ensembl chr15:23,553,128...23,564,535
|
|
G |
Cenpa |
centromere protein A |
affects response to substance |
ISO |
CENPA protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 6:27,072,259...27,080,863
Ensembl chr 6:27,072,166...27,080,856
|
|
G |
Ckap2 |
cytoskeleton associated protein 2 |
affects response to substance |
ISO |
CKAP2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr16:74,752,655...74,779,184
Ensembl chr16:74,752,655...74,779,184
|
|
G |
Cox17 |
cytochrome c oxidase copper chaperone COX17 |
affects response to substance |
ISO |
COX17 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr11:64,962,663...64,968,437
Ensembl chr11:64,962,666...64,968,437
|
|
G |
Cox5a |
cytochrome c oxidase subunit 5A |
affects response to substance |
ISO |
COX5A protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 8:62,298,358...62,309,765
Ensembl chr 8:62,298,358...62,309,765
|
|
G |
Cox6b1 |
cytochrome c oxidase subunit 6B1 |
affects response to substance |
ISO |
COX6B1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 1:89,075,987...89,084,834
Ensembl chr 1:89,075,975...89,084,859 Ensembl chr 2:89,075,975...89,084,859
|
|
G |
Cp |
ceruloplasmin |
increases expression |
EXP |
Vinblastine results in increased expression of CP mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
|
|
G |
Creg1 |
cellular repressor of E1A-stimulated genes 1 |
affects response to substance |
ISO |
CREG1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr13:83,972,186...83,984,675
Ensembl chr13:83,972,212...83,984,675
|
|
G |
Cript |
CXXC repeat containing interactor of PDZ3 domain |
affects response to substance |
ISO |
CRIPT protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 6:10,594,147...10,602,103
Ensembl chr 6:10,594,122...10,602,085
|
|
G |
Ctss |
cathepsin S |
increases expression |
EXP |
Vinblastine results in increased expression of CTSS mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 2:197,655,780...197,679,768
Ensembl chr 2:197,655,786...197,679,458
|
|
G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
Vinblastine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] |
CTD |
PMID:11602686 |
|
NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
|
|
G |
Dcps |
decapping enzyme, scavenger |
affects response to substance |
ISO |
DCPS protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 8:36,321,992...36,374,665
Ensembl chr 8:36,321,993...36,374,673
|
|
G |
Ddx23 |
DEAD-box helicase 23 |
affects response to substance |
ISO |
DDX23 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 7:140,325,453...140,342,730
Ensembl chr 7:140,325,431...140,342,727
|
|
G |
Dera |
deoxyribose-phosphate aldolase |
affects response to substance |
ISO |
DERA protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 4:171,748,254...171,826,414
Ensembl chr 4:171,748,273...171,826,409
|
|
G |
Dffb |
DNA fragmentation factor subunit beta |
affects response to substance |
ISO |
DFFB protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 5:171,250,559...171,261,875
Ensembl chr 5:171,249,633...171,262,119
|
|
G |
Dipk1a |
divergent protein kinase domain 1A |
affects response to substance |
ISO |
DIPK1A protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr14:2,789,699...2,860,354
Ensembl chr14:2,789,650...2,860,333
|
|
G |
Dkk1 |
dickkopf WNT signaling pathway inhibitor 1 |
affects response to substance |
ISO |
DKK1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
|
|
G |
Dkk3 |
dickkopf WNT signaling pathway inhibitor 3 |
affects response to substance |
ISO |
DKK3 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 1:176,940,424...176,983,076
Ensembl chr 1:176,940,693...176,983,045
|
|
G |
Donson |
DNA replication fork stabilization factor DONSON |
affects response to substance |
ISO |
DONSON protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr11:31,834,608...31,847,751
Ensembl chr11:31,837,839...31,847,490
|
|
G |
Dscc1 |
DNA replication and sister chromatid cohesion 1 |
affects response to substance |
ISO |
DSCC1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 7:94,759,076...94,774,787
Ensembl chr 7:94,758,800...94,774,569
|
|
G |
E2f1 |
E2F transcription factor 1 |
increases response to substance |
ISO |
E2F1 protein results in increased susceptibility to Vinblastine |
CTD |
PMID:16849574 |
|
NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
|
|
G |
Ednrb |
endothelin receptor type B |
increases expression |
EXP |
Vinblastine results in increased expression of EDNRB mRNA |
CTD |
PMID:20624997 |
|
NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
|
|
G |
Efcab7 |
EF-hand calcium binding domain 7 |
affects response to substance |
ISO |
EFCAB7 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 5:118,673,835...118,724,581
Ensembl chr 5:118,541,979...118,724,581
|
|
G |
Emp2 |
epithelial membrane protein 2 |
affects response to substance |
ISO |
EMP2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr10:5,433,248...5,467,840
Ensembl chr10:5,433,248...5,467,839
|
|
G |
Epcam |
epithelial cell adhesion molecule |
affects response to substance |
ISO |
EPCAM protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 6:11,282,194...11,308,870
Ensembl chr 6:11,281,964...11,298,216
|
|
G |
Eprs |
glutamyl-prolyl-tRNA synthetase |
increases expression |
EXP |
Vinblastine results in increased expression of EPRS mRNA |
CTD |
PMID:20624997 |
|
NCBI chr13:103,300,911...103,371,651
Ensembl chr13:103,300,932...103,371,577
|
|
G |
Erbb2 |
erb-b2 receptor tyrosine kinase 2 |
affects response to substance |
ISO |
ERBB2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:10327070 |
|
NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
|
|
G |
Ereg |
epiregulin |
affects response to substance |
ISO |
EREG protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
|
|
G |
Esm1 |
endothelial cell-specific molecule 1 |
decreases expression |
EXP |
Vinblastine results in decreased expression of ESM1 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 2:45,104,392...45,113,130
Ensembl chr 2:45,104,305...45,113,131
|
|
G |
Etfb |
electron transfer flavoprotein subunit beta |
affects response to substance |
ISO |
ETFB protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 1:98,472,776...98,486,940
Ensembl chr 1:98,472,745...98,486,976
|
|
G |
Exosc9 |
exosome component 9 |
affects response to substance |
ISO |
EXOSC9 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 2:123,264,679...123,275,623
Ensembl chr 2:123,264,694...123,294,880
|
|
G |
F3 |
coagulation factor III, tissue factor |
increases expression |
EXP |
Vinblastine results in increased expression of F3 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
|
|
G |
Fam3c |
FAM3 metabolism regulating signaling molecule C |
affects response to substance |
ISO |
FAM3C protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 4:49,388,962...49,439,892
Ensembl chr 4:49,387,989...49,439,867
|
|
G |
Fancl |
FA complementation group L |
affects response to substance |
ISO |
FANCL protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr14:110,675,306...110,740,880
Ensembl chr14:110,676,090...110,740,317
|
|
G |
Faslg |
Fas ligand |
increases expression |
ISO |
Vinblastine results in increased expression of FASLG protein |
CTD |
PMID:11716366 |
|
NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
|
|
G |
Fcgr2b |
Fc fragment of IgG receptor IIb |
increases expression |
EXP |
Vinblastine results in increased expression of FCGR2B mRNA |
CTD |
PMID:20624997 |
|
NCBI chr13:89,329,298...89,343,916
Ensembl chr13:89,327,794...89,433,815
|
|
G |
Fen1 |
flap structure-specific endonuclease 1 |
affects response to substance |
ISO |
FEN1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 1:226,251,516...226,256,160
Ensembl chr 1:226,251,518...226,255,886
|
|
G |
Fkbp1a |
FKBP prolyl isomerase 1A |
affects response to substance |
ISO |
FKBP1A protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 3:147,042,944...147,062,725
Ensembl chr 3:147,042,944...147,062,724
|
|
G |
Fli1 |
Fli-1 proto-oncogene, ETS transcription factor |
affects response to substance |
ISO |
FLI1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 8:33,541,932...33,661,111
Ensembl chr 8:33,543,258...33,661,049
|
|
G |
Fn1 |
fibronectin 1 |
affects response to substance |
ISO |
FN1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
|
|
G |
Fosl1 |
FOS like 1, AP-1 transcription factor subunit |
affects response to substance |
ISO |
FOSL1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
|
|
G |
G0s2 |
G0/G1switch 2 |
affects response to substance |
ISO |
G0S2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr13:112,004,140...112,005,052
Ensembl chr13:112,004,140...112,005,052
|
|
G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
increases expression |
EXP |
Vinblastine results in increased expression of GADD45A mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
|
|
G |
Gadd45b |
growth arrest and DNA-damage-inducible, beta |
increases expression |
EXP |
Vinblastine results in increased expression of GADD45B mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322
|
|
G |
Gadd45g |
growth arrest and DNA-damage-inducible, gamma |
increases expression |
EXP |
Vinblastine results in increased expression of GADD45G mRNA |
CTD |
PMID:20624997 |
|
NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243
|
|
G |
Gas7 |
growth arrest specific 7 |
decreases expression |
EXP |
Vinblastine results in decreased expression of GAS7 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr10:54,010,723...54,240,805
Ensembl chr10:54,126,486...54,236,476
|
|
G |
Ggct |
gamma-glutamyl cyclotransferase |
affects response to substance |
ISO |
GGCT protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 4:85,186,644...85,192,857
Ensembl chr 4:85,186,644...85,192,834
|
|
G |
Ggcx |
gamma-glutamyl carboxylase |
affects response to substance |
ISO |
GGCX protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 4:100,277,345...100,293,097
Ensembl chr 4:100,277,391...100,293,250
|
|
G |
Gmnn |
geminin, DNA replication inhibitor |
affects response to substance |
ISO |
GMNN protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr17:42,302,523...42,310,783
Ensembl chr17:42,302,540...42,310,783
|
|
G |
Gnptab |
N-acetylglucosamine-1-phosphate transferase subunits alpha and beta |
affects response to substance |
ISO |
GNPTAB protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 7:28,956,363...29,023,232
Ensembl chr 7:28,956,512...29,022,868
|
|
G |
Gpr176 |
G protein-coupled receptor 176 |
affects response to substance |
ISO |
GPR176 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 3:110,042,853...110,140,756
Ensembl chr 3:110,042,853...110,140,756
|
|
G |
Gpsm2 |
G-protein signaling modulator 2 |
affects response to substance |
ISO |
GPSM2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 2:211,480,120...211,528,096
Ensembl chr 2:211,480,400...211,527,919
|
|
G |
Gstp1 |
glutathione S-transferase pi 1 |
decreases response to substance |
EXP |
GSTP1 protein results in decreased susceptibility to Vinblastine |
CTD |
PMID:11455017 |
|
NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
|
|
G |
Gtf2i |
general transcription factor II I |
affects response to substance |
ISO |
GTF2I protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr12:25,410,804...25,487,970
Ensembl chr12:25,411,207...25,488,156
|
|
G |
Gtf3a |
general transcription factor III A |
affects response to substance |
ISO |
GTF3A protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr12:9,856,841...9,864,791
Ensembl chr12:9,856,842...9,864,791
|
|
G |
Gtse1 |
G-2 and S-phase expressed 1 |
affects response to substance |
ISO |
GTSE1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 7:126,736,416...126,753,221
Ensembl chr 7:126,736,732...126,753,220
|
|
G |
Gusb |
glucuronidase, beta |
affects response to substance |
ISO |
GUSB protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr12:30,202,066...30,215,583
Ensembl chr12:30,198,822...30,227,771
|
|
G |
H1f2 |
H1.2 linker histone, cluster member |
affects response to substance |
ISO |
H1-2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr17:43,638,938...43,640,445
Ensembl chr17:43,639,749...43,640,387
|
|
G |
Hadh |
hydroxyacyl-CoA dehydrogenase |
affects response to substance |
ISO |
HADH protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 2:236,353,445...236,395,067
Ensembl chr 2:236,353,445...236,395,067
|
|
G |
Hcls1 |
hematopoietic cell specific Lyn substrate 1 |
affects response to substance |
ISO |
HCLS1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr11:66,736,966...66,759,402
Ensembl chr11:66,736,966...66,759,402
|
|
G |
Hmgb1 |
high mobility group box 1 |
affects response to substance |
ISO |
HMGB1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
|
|
G |
Hmgb2 |
high mobility group box 2 |
affects response to substance |
ISO |
HMGB2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr16:36,077,615...36,080,191
Ensembl chr16:36,077,617...36,080,191 Ensembl chr11:36,077,617...36,080,191
|
|
G |
Hmgn3 |
high mobility group nucleosomal binding domain 3 |
affects response to substance |
ISO |
HMGN3 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 8:90,628,203...90,665,055
Ensembl chr 8:90,628,209...90,664,554
|
|
G |
Hmmr |
hyaluronan-mediated motility receptor |
affects response to substance |
ISO |
HMMR protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr10:25,861,490...25,890,639
Ensembl chr10:25,861,490...25,890,639
|
|
G |
Hmox1 |
heme oxygenase 1 |
increases expression |
EXP |
Vinblastine results in increased expression of HMOX1 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
|
|
G |
Homer1 |
homer scaffold protein 1 |
affects response to substance |
ISO |
HOMER1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 2:22,909,550...23,012,303
Ensembl chr 2:22,909,569...23,009,678
|
|
G |
Icam1 |
intercellular adhesion molecule 1 |
increases expression decreases expression |
EXP ISO |
Vinblastine results in increased expression of ICAM1 mRNA Vinblastine results in decreased expression of ICAM1 mRNA; Vinblastine results in decreased expression of ICAM1 protein |
CTD |
PMID:12649748 PMID:20624997 |
|
NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
|
|
G |
Id2 |
inhibitor of DNA binding 2 |
affects response to substance |
ISO |
ID2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915
|
|
G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
affects response to substance |
ISO |
IDH2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
|
|
G |
Igf2bp3 |
insulin-like growth factor 2 mRNA binding protein 3 |
affects response to substance |
ISO |
IGF2BP3 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 4:78,744,683...78,879,457
Ensembl chr 4:78,746,547...78,879,294
|
|
G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
increases phosphorylation multiple interactions |
ISO |
Vinblastine results in increased phosphorylation of IKBKB protein Vinblastine results in decreased localization of [IKBKB protein binds to NFKBIA protein] |
CTD |
PMID:17029595 |
|
NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
|
|
G |
Il13ra2 |
interleukin 13 receptor subunit alpha 2 |
affects response to substance |
ISO |
IL13RA2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr X:118,443,955...118,514,716
Ensembl chr X:118,443,823...118,513,061
|
|
G |
Il1b |
interleukin 1 beta |
affects response to substance increases expression |
ISO EXP |
IL1B protein affects the susceptibility to Vinblastine Vinblastine results in increased expression of IL1B mRNA |
CTD |
PMID:16217747 PMID:20624997 |
|
NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
|
|
G |
Il6 |
interleukin 6 |
decreases chemical synthesis increases stability |
ISO |
Vinblastine results in decreased chemical synthesis of IL6 protein Vinblastine results in increased stability of IL6 mRNA |
CTD |
PMID:16499908 |
|
NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
|
|
G |
Inha |
inhibin subunit alpha |
decreases expression |
EXP |
Vinblastine results in decreased expression of INHA mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 9:82,700,482...82,703,383
Ensembl chr 9:82,700,468...82,703,400
|
|
G |
Inhba |
inhibin subunit beta A |
affects response to substance |
ISO |
INHBA protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr17:51,894,869...51,919,998
Ensembl chr17:51,898,217...51,912,496
|
|
G |
Itgal |
integrin subunit alpha L |
decreases expression |
ISO |
Vinblastine results in decreased expression of ITGAL mRNA; Vinblastine results in decreased expression of ITGAL protein |
CTD |
PMID:12649748 |
|
NCBI chr 1:198,744,053...198,781,745
Ensembl chr 1:198,744,050...198,781,750
|
|
G |
Itgb1bp1 |
integrin subunit beta 1 binding protein 1 |
affects response to substance |
ISO |
ITGB1BP1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 6:43,348,927...43,363,633
Ensembl chr 6:43,348,958...43,363,335
|
|
G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases phosphorylation |
ISO |
TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of JUN protein] |
CTD |
PMID:12221076 |
|
NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
|
|
G |
Kank1 |
KN motif and ankyrin repeat domains 1 |
affects response to substance |
ISO |
KANK1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 1:243,201,073...243,398,531
Ensembl chr 1:243,276,403...243,398,536
|
|
G |
Kazn |
kazrin, periplakin interacting protein |
affects response to substance |
ISO |
KAZN protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 5:160,637,235...161,730,513
Ensembl chr 5:160,639,578...160,742,479
|
|
G |
Kif11 |
kinesin family member 11 |
affects response to substance |
ISO |
KIF11 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 1:256,035,866...256,088,299
Ensembl chr 1:256,035,866...256,088,299
|
|
G |
Kif15 |
kinesin family member 15 |
affects response to substance |
ISO |
KIF15 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 8:132,033,117...132,103,528
Ensembl chr 8:132,032,944...132,103,927
|
|
G |
Kif1b |
kinesin family member 1B |
affects response to substance |
ISO |
KIF1B protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 5:165,994,803...166,133,497
Ensembl chr 5:165,938,576...166,133,491
|
|
G |
Kif20a |
kinesin family member 20A |
affects response to substance |
ISO |
KIF20A protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr18:27,424,328...27,432,814
Ensembl chr18:27,424,328...27,432,814
|
|
G |
Kif23 |
kinesin family member 23 |
affects response to substance |
ISO |
KIF23 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 8:66,866,043...66,893,241
Ensembl chr 8:66,866,082...66,893,196
|
|
G |
Kif4a |
kinesin family member 4A |
affects response to substance |
ISO |
KIF4A protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr X:70,461,700...70,561,084
Ensembl chr X:70,461,718...70,561,189
|
|
G |
Kpna2 |
karyopherin subunit alpha 2 |
affects response to substance |
ISO |
KPNA2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr10:95,200,029...95,212,111
Ensembl chr10:95,200,030...95,212,111
|
|
G |
Lmnb1 |
lamin B1 |
affects response to substance |
ISO |
LMNB1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr18:51,785,111...51,822,264
Ensembl chr18:51,785,111...51,822,264
|
|
G |
Lpar1 |
lysophosphatidic acid receptor 1 |
affects response to substance |
ISO |
LPAR1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 5:75,557,038...75,678,067
Ensembl chr 5:75,557,042...75,676,584
|
|
G |
Lrrc1 |
leucine rich repeat containing 1 |
affects response to substance |
ISO |
LRRC1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 8:84,721,621...84,835,074
Ensembl chr 8:84,720,551...84,835,060
|
|
G |
Lsm7 |
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated |
affects response to substance |
ISO |
LSM7 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 7:11,724,932...11,732,020
Ensembl chr 7:11,724,962...11,727,388
|
|
G |
Ltbp2 |
latent transforming growth factor beta binding protein 2 |
affects response to substance |
ISO |
LTBP2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 6:108,500,114...108,596,653
Ensembl chr 6:108,500,112...108,596,569
|
|
G |
Mad2l1 |
mitotic arrest deficient 2 like 1 |
affects response to substance |
ISO |
MAD2L1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 4:97,530,993...97,543,179
Ensembl chr 4:97,531,083...97,537,086
|
|
G |
Mapk8 |
mitogen-activated protein kinase 8 |
increases phosphorylation multiple interactions |
ISO |
Vinblastine results in increased phosphorylation of MAPK8 protein TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of MAPK8 protein] |
CTD |
PMID:12221076 |
|
NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
|
|
G |
Mapk9 |
mitogen-activated protein kinase 9 |
multiple interactions increases phosphorylation |
ISO |
TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of MAPK9 protein] |
CTD |
PMID:12221076 |
|
NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
|
|
G |
Mapkapk5 |
MAPK activated protein kinase 5 |
affects response to substance |
ISO |
MAPKAPK5 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr12:40,510,378...40,529,332
Ensembl chr12:40,510,378...40,529,338
|
|
G |
Melk |
maternal embryonic leucine zipper kinase |
affects response to substance |
ISO |
MELK protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 5:59,783,835...59,844,356
Ensembl chr 5:59,783,890...59,844,356
|
|
G |
Mme |
membrane metallo-endopeptidase |
affects response to substance |
ISO |
MME protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 2:153,799,203...153,880,910
Ensembl chr 2:153,803,349...153,880,738
|
|
G |
Mmp1 |
matrix metallopeptidase 1 |
affects response to substance |
ISO |
MMP1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
|
|
G |
Mok |
MOK protein kinase |
affects response to substance |
ISO |
MOK protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 6:135,228,755...135,259,645
Ensembl chr 6:135,228,803...135,259,603
|
|
G |
Mrpl57 |
mitochondrial ribosomal protein L57 |
affects response to substance |
ISO |
MRPL57 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr15:38,096,994...38,097,856
Ensembl chr15:38,095,803...38,097,835
|
|
G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
affects response to substance increases expression |
ISO EXP |
MYC protein affects the susceptibility to Vinblastine Vinblastine results in increased expression of MYC mRNA |
CTD |
PMID:18802399 PMID:20624997 |
|
NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
|
|
G |
Mycbp |
Myc binding protein |
affects response to substance |
ISO |
MYCBP protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 5:141,560,192...141,567,399
Ensembl chr 5:141,560,192...141,567,399
|
|
G |
Nbn |
nibrin |
increases expression |
EXP |
Vinblastine results in increased expression of NBN mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 5:29,622,347...29,656,877
Ensembl chr 5:29,622,281...29,656,864
|
|
G |
Ncapg |
non-SMC condensin I complex, subunit G |
affects response to substance |
ISO |
NCAPG protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr14:69,898,268...69,927,885
Ensembl chr14:69,899,128...69,927,938
|
|
G |
Ncaph |
non-SMC condensin I complex, subunit H |
affects response to substance |
ISO |
NCAPH protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 3:119,583,798...119,611,148
Ensembl chr 3:119,583,648...119,611,136
|
|
G |
Ndc80 |
NDC80 kinetochore complex component |
affects response to substance |
ISO |
NDC80 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 9:119,837,857...119,871,435
Ensembl chr 9:119,839,016...119,871,382
|
|
G |
Ndufa1 |
NADH:ubiquinone oxidoreductase subunit A1 |
affects response to substance |
ISO |
NDUFA1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr X:123,803,109...123,806,760
Ensembl chr X:124,513,269...124,516,705 Ensembl chr X:124,513,269...124,516,705
|
|
G |
Ndufa13 |
NADH:ubiquinone oxidoreductase subunit A13 |
affects response to substance |
ISO |
NDUFA13 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr16:21,275,311...21,282,246
Ensembl chr16:21,275,311...21,282,246
|
|
G |
Ndufa3 |
NADH:ubiquinone oxidoreductase subunit A3 |
affects response to substance |
ISO |
NDUFA3 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 1:64,172,462...64,175,174
Ensembl chr 1:64,172,540...64,175,099
|
|
G |
Ndufa7 |
NADH:ubiquinone oxidoreductase subunit A7 |
affects response to substance |
ISO |
NDUFA7 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 7:18,683,553...18,696,332
Ensembl chr 7:18,683,553...18,696,330
|
|
G |
Ndufb2 |
NADH:ubiquinone oxidoreductase subunit B2 |
affects response to substance |
ISO |
NDUFB2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 4:67,378,188...67,385,267
Ensembl chr 4:67,378,188...67,385,266
|
|
G |
Ndufc1 |
NADH:ubiquinone oxidoreductase subunit C1 |
affects response to substance |
ISO |
NDUFC1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 2:140,460,749...140,464,588
Ensembl chr 2:140,462,900...140,464,607
|
|
G |
Ndufc2 |
NADH:ubiquinone oxidoreductase subunit C2 |
affects response to substance |
ISO |
NDUFC2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 1:162,369,801...162,376,024
Ensembl chr 1:162,369,801...162,376,023
|
|
G |
Ndufs6 |
NADH:ubiquinone oxidoreductase subunit S6 |
affects response to substance |
ISO |
NDUFS6 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 2:26,471,173...26,471,587
Ensembl chr 2:26,471,173...26,471,584
|
|
G |
Ndufv2 |
NADH:ubiquinone oxidoreductase core subunit V2 |
affects response to substance |
ISO |
NDUFV2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 9:113,875,718...113,900,169
Ensembl chr 9:113,875,703...113,900,190
|
|
G |
Nfatc4 |
nuclear factor of activated T-cells 4 |
decreases localization |
ISO |
Vinblastine results in decreased localization of NFATC4 protein |
CTD |
PMID:17044076 |
|
NCBI chr15:34,493,163...34,502,238
Ensembl chr15:34,493,138...34,504,326
|
|
G |
Nfkbia |
NFKB inhibitor alpha |
increases phosphorylation multiple interactions |
ISO |
Vinblastine results in increased phosphorylation of NFKBIA protein Vinblastine results in decreased localization of [IKBKB protein binds to NFKBIA protein] |
CTD |
PMID:17029595 |
|
NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
|
|
G |
Ngf |
nerve growth factor |
decreases response to substance |
EXP |
Vinblastine results in decreased susceptibility to NGF protein |
CTD |
PMID:9524088 |
|
NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
|
|
G |
Npy |
neuropeptide Y |
decreases expression |
EXP |
Vinblastine results in decreased expression of NPY mRNA |
CTD |
PMID:1671012 |
|
NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
|
|
G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
multiple interactions |
ISO |
Vinblastine inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] |
CTD |
PMID:25257666 |
|
NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
|
|
G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
multiple interactions increases activity |
ISO |
[Vinblastine results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; NR1I2 protein promotes the reaction [Vinblastine results in increased expression of ABCB1 protein] |
CTD |
PMID:20041327 |
|
NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
|
|
G |
Nsmaf |
neutral sphingomyelinase activation associated factor |
affects response to substance |
ISO |
NSMAF protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 5:19,499,111...19,560,308
Ensembl chr 5:19,499,480...19,559,393
|
|
G |
Nudt15 |
nudix hydrolase 15 |
affects response to substance |
ISO |
NUDT15 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr15:55,417,774...55,456,698
Ensembl chr15:55,419,502...55,456,698
|
|
G |
Nudt4 |
nudix hydrolase 4 |
affects response to substance |
ISO |
NUDT4 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 7:36,643,916...36,660,334
Ensembl chr 7:36,643,916...36,660,141
|
|
G |
Nusap1 |
nucleolar and spindle associated protein 1 |
affects response to substance |
ISO |
NUSAP1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 3:111,422,267...111,452,600
Ensembl chr 3:111,422,267...111,452,971
|
|
G |
Oaz1 |
ornithine decarboxylase antizyme 1 |
affects response to substance |
ISO |
OAZ1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 7:11,752,127...11,754,587
Ensembl chr 7:11,752,412...11,754,508
|
|
G |
Odc1 |
ornithine decarboxylase 1 |
multiple interactions |
ISO |
Vinblastine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein] |
CTD |
PMID:9270009 |
|
NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
|
|
G |
Oip5 |
Opa interacting protein 5 |
affects response to substance |
ISO |
OIP5 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 3:111,413,662...111,422,320
Ensembl chr 3:111,416,536...111,422,203
|
|
G |
Olr1087 |
olfactory receptor 1087 |
affects response to substance |
ISO |
OR1I1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 7:13,996,966...13,997,907
Ensembl chr 7:13,996,966...13,997,907
|
|
G |
Orc6 |
origin recognition complex, subunit 6 |
affects response to substance |
ISO |
ORC6 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr19:27,457,541...27,464,804
Ensembl chr19:27,457,474...27,464,805
|
|
G |
Osbpl10 |
oxysterol binding protein-like 10 |
affects response to substance |
ISO |
OSBPL10 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 8:123,029,722...123,303,553
Ensembl chr 8:123,126,667...123,293,562
|
|
G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions |
ISO |
CD40LG protein inhibits the reaction [Vinblastine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]; Vinblastine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein] |
CTD |
PMID:16545138 |
|
NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
|
|
G |
Pdhb |
pyruvate dehydrogenase E1 subunit beta |
affects response to substance |
ISO |
PDHB protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr15:18,540,826...18,546,855
Ensembl chr15:18,539,210...18,546,854
|
|
G |
Pelo |
pelota mRNA surveillance and ribosome rescue factor |
affects response to substance |
ISO |
PELO protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 2:47,266,758...47,268,526
Ensembl chr 2:47,266,738...47,268,625
|
|
G |
Pgrmc1 |
progesterone receptor membrane component 1 |
affects response to substance |
ISO |
PGRMC1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr X:123,205,869...123,213,880
Ensembl chr X:123,205,869...123,213,882
|
|
G |
Pir |
pirin |
affects response to substance |
ISO |
PIR protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr X:31,852,322...31,968,152
Ensembl chr X:31,852,323...31,968,152
|
|
G |
Plagl1 |
PLAG1 like zinc finger 1 |
increases expression |
EXP |
Vinblastine results in increased expression of PLAGL1 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 1:7,219,587...7,270,169
Ensembl chr 1:7,252,349...7,259,035
|
|
G |
Plat |
plasminogen activator, tissue type |
increases expression |
EXP |
Vinblastine results in increased expression of PLAT mRNA |
CTD |
PMID:20624997 |
|
NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
|
|
G |
Plau |
plasminogen activator, urokinase |
affects response to substance |
ISO |
PLAU protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
|
|
G |
Plaur |
plasminogen activator, urokinase receptor |
increases expression |
EXP |
Vinblastine results in increased expression of PLAUR mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 1:81,328,171...81,344,954
Ensembl chr 1:81,328,183...81,344,708
|
|
G |
Ppp1r15a |
protein phosphatase 1, regulatory subunit 15A |
increases expression |
EXP |
Vinblastine results in increased expression of PPP1R15A mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
|
|
G |
Prc1 |
protein regulator of cytokinesis 1 |
affects response to substance |
ISO |
PRC1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 1:142,087,181...142,108,746
Ensembl chr 1:142,087,208...142,108,746
|
|
G |
Prkcd |
protein kinase C, delta |
affects localization |
ISO |
Vinblastine affects the localization of PRKCD protein |
CTD |
PMID:9852137 |
|
NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
|
|
G |
Psmb1 |
proteasome 20S subunit beta 1 |
affects response to substance |
ISO |
PSMB1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 1:57,470,878...57,491,359
Ensembl chr 1:57,470,632...57,489,727
|
|
G |
Psme4 |
proteasome activator subunit 4 |
affects response to substance |
ISO |
PSME4 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr14:115,166,165...115,269,041
Ensembl chr14:115,166,416...115,269,056
|
|
G |
Ptges3 |
prostaglandin E synthase 3 |
affects response to substance |
ISO |
PTGES3 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 7:2,479,267...2,497,024
Ensembl chr 7:2,479,311...2,497,013
|
|
G |
Pttg1 |
PTTG1 regulator of sister chromatid separation, securin |
affects response to substance |
ISO |
PTTG1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr10:29,014,332...29,026,088
Ensembl chr10:29,020,049...29,026,002
|
|
G |
Ptx3 |
pentraxin 3 |
affects response to substance |
ISO |
PTX3 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 2:158,097,843...158,103,653
Ensembl chr 2:158,097,843...158,103,653
|
|
G |
Qrich1 |
glutamine-rich 1 |
increases phosphorylation |
ISO |
Vinblastine results in increased phosphorylation of QRICH1 protein |
CTD |
PMID:17510977 |
|
NCBI chr 8:117,305,803...117,346,738
Ensembl chr 8:117,307,339...117,346,736
|
|
G |
Rab11fip1 |
RAB11 family interacting protein 1 |
affects response to substance |
ISO |
RAB11FIP1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr16:69,048,739...69,079,332
Ensembl chr16:69,046,514...69,079,332
|
|
G |
Racgap1 |
Rac GTPase-activating protein 1 |
affects response to substance |
ISO |
RACGAP1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 7:141,277,303...141,308,849
Ensembl chr 7:141,277,312...141,307,233
|
|
G |
Ranbp1 |
RAN binding protein 1 |
affects response to substance |
ISO |
RANBP1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr11:86,890,585...86,898,818
Ensembl chr11:86,890,585...86,898,818
|
|
G |
Rassf1 |
Ras association domain family member 1 |
increases expression |
EXP |
Vinblastine results in increased expression of RASSF1 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 8:116,307,149...116,318,289
Ensembl chr 8:116,307,141...116,318,289
|
|
G |
Rev3l |
REV3 like, DNA directed polymerase zeta catalytic subunit |
affects response to substance |
ISO |
REV3L protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr20:44,803,664...44,961,362
Ensembl chr20:44,803,666...44,961,382
|
|
G |
Rfc5 |
replication factor C subunit 5 |
affects response to substance |
ISO |
RFC5 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr12:44,931,494...44,941,051
Ensembl chr12:44,931,494...44,941,324
|
|
G |
RGD1310352 |
similar to HTGN29 protein; keratinocytes associated transmembrane protein 2 |
affects response to substance |
ISO |
C5ORF15 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr10:37,757,131...37,769,781
Ensembl chr10:37,757,146...37,769,776
|
|
G |
Rpa3 |
replication protein A3 |
affects response to substance |
ISO |
RPA3 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 4:34,279,320...34,282,351
Ensembl chr 4:34,279,320...34,282,351
|
|
G |
Rrm2 |
ribonucleotide reductase regulatory subunit M2 |
affects response to substance |
ISO |
RRM2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 6:43,884,627...43,890,818
Ensembl chr 6:43,884,678...43,889,515
|
|
G |
S100a8 |
S100 calcium binding protein A8 |
increases expression |
EXP |
Vinblastine results in increased expression of S100A8 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
|
|
G |
S100a9 |
S100 calcium binding protein A9 |
increases expression |
EXP |
Vinblastine results in increased expression of S100A9 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276
|
|
G |
Sele |
selectin E |
increases expression |
EXP |
Vinblastine results in increased expression of SELE mRNA |
CTD |
PMID:20624997 |
|
NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
|
|
G |
Serpinb2 |
serpin family B member 2 |
affects response to substance |
ISO |
SERPINB2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr13:27,449,907...27,463,015
Ensembl chr13:27,449,934...27,463,010
|
|
G |
Serpine1 |
serpin family E member 1 |
increases expression affects response to substance |
EXP ISO |
Vinblastine results in increased expression of SERPINE1 mRNA SERPINE1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 PMID:20624997 |
|
NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
|
|
G |
Sfxn1 |
sideroflexin 1 |
affects response to substance |
ISO |
SFXN1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr17:11,046,588...11,082,219
Ensembl chr17:11,045,761...11,082,047
|
|
G |
Shtn1 |
shootin 1 |
affects response to substance |
ISO |
SHTN1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 1:280,129,228...280,233,873
Ensembl chr 1:280,130,504...280,233,929
|
|
G |
Skp2 |
S-phase kinase associated protein 2 |
affects response to substance |
ISO |
SKP2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 2:58,506,146...58,534,211
Ensembl chr 2:58,506,151...58,534,211
|
|
G |
Slc22a3 |
solute carrier family 22 member 3 |
affects response to substance |
ISO |
SLC22A3 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 1:48,433,079...48,521,261
Ensembl chr 1:48,433,079...48,521,256
|
|
G |
Snrnp25 |
small nuclear ribonucleoprotein U11/U12 subunit 25 |
affects response to substance |
ISO |
SNRNP25 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr10:15,685,999...15,689,338
Ensembl chr10:15,686,008...15,689,325
|
|
G |
Snx10 |
sorting nexin 10 |
affects response to substance |
ISO |
SNX10 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 4:81,311,490...81,375,248
Ensembl chr 4:81,311,490...81,374,158
|
|
G |
Sod1 |
superoxide dismutase 1 |
affects response to substance |
ISO |
SOD1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
|
|
G |
Sod2 |
superoxide dismutase 2 |
multiple interactions increases expression |
ISO |
bisindolylmaleimide I inhibits the reaction [Vinblastine results in increased expression of SOD2 mRNA]; calphostin C inhibits the reaction [Vinblastine results in increased expression of SOD2 mRNA]; Cycloheximide promotes the reaction [Vinblastine results in increased expression of SOD2 mRNA]; Dactinomycin inhibits the reaction [Vinblastine results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Vinblastine results in increased expression of SOD2 mRNA] |
CTD |
PMID:9852137 |
|
NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
|
|
G |
Sort1 |
sortilin 1 |
affects response to substance |
ISO |
SORT1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 2:211,078,092...211,156,312
Ensembl chr 2:211,078,334...211,156,312
|
|
G |
Spon1 |
spondin 1 |
increases expression |
EXP |
Vinblastine results in increased expression of SPON1 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 1:178,568,777...178,935,715
Ensembl chr 1:178,636,544...178,935,051
|
|
G |
Srd5a1 |
steroid 5 alpha-reductase 1 |
affects response to substance |
ISO |
SRD5A1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 1:36,320,504...36,354,694
Ensembl chr 1:36,320,461...36,354,756
|
|
G |
Srgn |
serglycin |
affects response to substance |
ISO |
SRGN protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr20:32,120,317...32,158,071
Ensembl chr20:32,120,320...32,139,789
|
|
G |
Stat1 |
signal transducer and activator of transcription 1 |
multiple interactions |
ISO |
Vinblastine deficiency results in decreased activity of and affects the localization of STAT1 protein |
CTD |
PMID:28086195 |
|
NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
|
|
G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions |
ISO |
Vinblastine deficiency results in decreased activity of and affects the localization of STAT3 protein |
CTD |
PMID:28086195 |
|
NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
|
|
G |
Stc2 |
stanniocalcin 2 |
affects response to substance |
ISO |
STC2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr10:16,542,909...16,552,675
Ensembl chr10:16,542,882...16,553,295
|
|
G |
Stk26 |
serine/threonine kinase 26 |
affects response to substance |
ISO |
STK26 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr X:138,032,356...138,096,632
Ensembl chr X:138,046,494...138,096,669
|
|
G |
Strn |
striatin |
affects response to substance |
ISO |
STRN protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 6:1,232,729...1,319,603
Ensembl chr 6:1,237,758...1,319,541
|
|
G |
Sucla2 |
succinate-CoA ligase ADP-forming subunit beta |
affects response to substance |
ISO |
SUCLA2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr15:55,461,695...55,516,954
Ensembl chr15:55,461,695...55,516,952
|
|
G |
Suclg1 |
succinate-CoA ligase GDP/ADP-forming subunit alpha |
affects response to substance |
ISO |
SUCLG1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 4:101,181,315...101,210,692
Ensembl chr 4:101,180,404...101,210,746
|
|
G |
Sult1a1 |
sulfotransferase family 1A member 1 |
affects response to substance |
ISO |
SULT1A1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
|
|
G |
Syde1 |
synapse defective Rho GTPase homolog 1 |
affects response to substance |
ISO |
SYDE1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 7:14,037,646...14,043,632
Ensembl chr 7:14,037,620...14,043,779
|
|
G |
Tbc1d4 |
TBC1 domain family, member 4 |
affects response to substance |
ISO |
TBC1D4 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr15:85,927,978...86,105,829
Ensembl chr15:85,930,044...86,105,273
|
|
G |
Tdg |
thymine-DNA glycosylase |
affects response to substance |
ISO |
TDG protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 7:27,194,000...27,213,676
Ensembl chr 7:27,193,998...27,214,236
|
|
G |
Tfpi2 |
tissue factor pathway inhibitor 2 |
affects response to substance increases expression |
ISO EXP |
TFPI2 protein affects the susceptibility to Vinblastine Vinblastine results in increased expression of TFPI2 mRNA |
CTD |
PMID:16217747 PMID:20624997 |
|
NCBI chr 4:28,947,951...28,953,261
Ensembl chr 4:28,947,965...28,953,067
|
|
G |
Thbd |
thrombomodulin |
increases expression |
EXP |
Vinblastine results in increased expression of THBD mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
|
|
G |
Thbs1 |
thrombospondin 1 |
increases expression |
EXP |
Vinblastine results in increased expression of THBS1 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
|
|
G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
increases expression |
EXP |
Vinblastine results in increased expression of TIMP1 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr X:1,364,771...1,369,451
Ensembl chr X:1,364,786...1,369,384
|
|
G |
Tmem134 |
transmembrane protein 134 |
affects response to substance |
ISO |
TMEM134 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 1:219,374,005...219,383,365
Ensembl chr 1:219,374,060...219,379,557
|
|
G |
Tmem14a |
transmembrane protein 14A |
affects response to substance |
ISO |
TMEM14A protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 9:27,333,956...27,345,612 NCBI chr 9:27,334,103...27,351,302
Ensembl chr 9:27,343,853...27,345,070 Ensembl chr 9:27,343,853...27,345,070
|
|
G |
Tmem156 |
transmembrane protein 156 |
affects response to substance |
ISO |
TMEM156 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr14:44,888,902...44,918,377
Ensembl chr14:44,889,287...44,918,373
|
|
G |
Tmem97 |
transmembrane protein 97 |
affects response to substance |
ISO |
TMEM97 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr10:65,811,455...65,820,538
Ensembl chr10:65,811,456...65,820,538
|
|
G |
Tmpo |
thymopoietin |
affects response to substance |
ISO |
TMPO protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 7:31,847,412...31,872,416
Ensembl chr 7:31,847,410...31,872,423
|
|
G |
Top2a |
DNA topoisomerase II alpha |
affects response to substance |
ISO |
TOP2A protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
|
|
G |
Tp53 |
tumor protein p53 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of JUN protein]; TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of MAPK8 protein]; TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of MAPK9 protein] |
CTD |
PMID:12221076 |
|
NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
|
|
G |
Tpd52l1 |
TPD52 like 1 |
increases expression affects response to substance |
EXP ISO |
Vinblastine results in increased expression of TPD52L1 mRNA TPD52L1 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 PMID:20624997 |
|
NCBI chr 1:28,454,949...28,578,736
Ensembl chr 1:28,454,966...28,576,553
|
|
G |
Trim2 |
tripartite motif-containing 2 |
affects response to substance |
ISO |
TRIM2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 2:183,145,096...183,223,819
Ensembl chr 2:183,145,089...183,213,228
|
|
G |
Trmt5 |
tRNA methyltransferase 5 |
affects response to substance |
ISO |
TRMT5 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 6:96,164,579...96,171,680
Ensembl chr 6:96,153,014...96,171,779
|
|
G |
Tspan13 |
tetraspanin 13 |
affects response to substance |
ISO |
TSPAN13 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 6:55,497,659...55,524,415
Ensembl chr 6:55,497,658...55,524,436
|
|
G |
Ttf2 |
transcription termination factor 2 |
affects response to substance |
ISO |
TTF2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 2:203,317,673...203,350,752
Ensembl chr 2:203,318,855...203,350,736
|
|
G |
Ttk |
Ttk protein kinase |
affects response to substance |
ISO |
TTK protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 8:91,368,065...91,405,995
Ensembl chr 8:91,368,111...91,405,993
|
|
G |
Tuba1b |
tubulin, alpha 1B |
decreases expression |
EXP |
Vinblastine results in decreased expression of TUBA1B mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 7:140,614,746...140,617,721
Ensembl chr 7:140,614,752...140,617,721
|
|
G |
Tuba4a |
tubulin, alpha 4A |
decreases expression |
EXP |
Vinblastine results in decreased expression of TUBA4A mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 9:82,415,599...82,419,918
Ensembl chr 9:82,415,605...82,419,288
|
|
G |
Tubb4b |
tubulin, beta 4B class IVb |
decreases expression |
EXP |
Vinblastine results in decreased expression of TUBB4B mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 3:2,441,585...2,444,369
Ensembl chr 3:2,441,733...2,444,281
|
|
G |
Tubb5 |
tubulin, beta 5 class I |
decreases expression |
EXP |
Vinblastine results in decreased expression of TUBB5 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr20:3,422,448...3,426,420
Ensembl chr20:3,422,461...3,426,371
|
|
G |
Tubg1 |
tubulin, gamma 1 |
decreases expression |
EXP |
Vinblastine results in decreased expression of TUBG1 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr10:89,030,865...89,037,455
Ensembl chr10:89,030,865...89,037,455
|
|
G |
Uqcr10 |
ubiquinol-cytochrome c reductase, complex III subunit X |
affects response to substance |
ISO |
UQCR10 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr14:84,935,480...84,937,741
Ensembl chr14:84,935,486...84,937,725
|
|
G |
Vcam1 |
vascular cell adhesion molecule 1 |
increases expression |
EXP |
Vinblastine results in increased expression of VCAM1 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
|
|
G |
Vegfa |
vascular endothelial growth factor A |
decreases expression |
EXP |
Vinblastine results in decreased expression of VEGFA mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
|
|
G |
Vegfc |
vascular endothelial growth factor C |
affects response to substance |
ISO |
VEGFC protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr16:40,440,371...40,555,178
Ensembl chr16:40,440,207...40,555,576
|
|
G |
Vwf |
von Willebrand factor |
increases expression |
EXP |
Vinblastine results in increased expression of VWF mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523
|
|
G |
Wdr61 |
WD repeat domain 61 |
affects response to substance |
ISO |
WDR61 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 8:59,296,339...59,313,663
Ensembl chr 8:59,296,346...59,313,574
|
|
G |
Wsb2 |
WD repeat and SOCS box-containing 2 |
affects response to substance |
ISO |
WSB2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr12:44,941,655...44,962,679
Ensembl chr12:44,942,443...44,962,656
|
|
G |
Ywhaq |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta |
affects response to substance |
ISO |
YWHAQ protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 6:43,463,294...43,493,816
Ensembl chr 6:43,463,294...43,493,816
|
|
G |
Zdhhc11 |
zinc finger, DHHC-type containing 11 |
affects response to substance |
ISO |
ZDHHC11 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 1:31,906,049...31,936,603
Ensembl chr 1:31,906,064...31,936,537
|
|
G |
Zfp36l2 |
zinc finger protein 36, C3H type-like 2 |
affects response to substance |
ISO |
ZFP36L2 protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr 6:7,417,416...7,423,447
Ensembl chr 6:7,417,425...7,421,456
|
|
G |
Zwint |
ZW10 interacting kinetochore protein |
affects response to substance |
ISO |
ZWINT protein affects the susceptibility to Vinblastine |
CTD |
PMID:16217747 |
|
NCBI chr20:17,075,781...17,091,715
Ensembl chr20:17,075,771...17,091,766
|
|
|
G |
Kcnh2 |
potassium voltage-gated channel subfamily H member 2 |
decreases activity |
ISO |
Vincamine results in decreased activity of KCNH2 protein |
CTD |
PMID:28551711 |
|
NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
|
|
|
G |
Aamdc |
adipogenesis associated, Mth938 domain containing |
increases expression |
ISO |
Vincristine results in increased expression of AAMDC mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:162,519,513...162,549,211
Ensembl chr 1:162,519,521...162,533,893
|
|
G |
Abca1 |
ATP binding cassette subfamily A member 1 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCA1 mRNA |
CTD |
PMID:19944135 |
|
NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
|
|
G |
Abca12 |
ATP binding cassette subfamily A member 12 |
increases expression multiple interactions |
ISO |
Vincristine results in increased expression of ABCA12 mRNA [Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCA12 mRNA |
CTD |
PMID:19944135 PMID:23649840 |
|
NCBI chr 9:78,521,477...78,693,421
Ensembl chr 9:78,522,464...78,693,028
|
|
G |
Abca4 |
ATP binding cassette subfamily A member 4 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCA4 mRNA |
CTD |
PMID:19944135 |
|
NCBI chr 2:225,645,539...225,783,288
Ensembl chr 2:225,645,568...225,783,287
|
|
G |
Abca5 |
ATP binding cassette subfamily A member 5 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCA5 mRNA |
CTD |
PMID:19944135 |
|
NCBI chr10:98,573,226...98,645,028
Ensembl chr10:98,576,039...98,644,938
|
|
G |
Abca8 |
ATP binding cassette subfamily A member 8 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCA8 mRNA |
CTD |
PMID:19944135 |
|
NCBI chr10:98,236,919...98,308,288
Ensembl chr10:98,237,141...98,294,522
|
|
G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
affects response to substance increases expression multiple interactions increases transport decreases uptake decreases response to substance affects uptake |
ISO EXP |
ABCB1 protein affects the susceptibility to Vincristine Vincristine results in increased expression of ABCB1A mRNA Vincristine results in increased expression of ABCB1 protein [Estradiol results in decreased expression of ABCB1 protein] which results in increased uptake of and results in increased susceptibility to Vincristine; [MGMT protein co-treated with ABCB1 protein] results in decreased susceptibility to Vincristine; [Paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to Vincristine; [Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCB1 mRNA; [Vincristine results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; CEP 33779 inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]; Cyclosporine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]; Fenofibrate inhibits the reaction [ABCB1 protein results in increased transport of Vincristine]; Flupenthixol analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]; NR1I2 protein promotes the reaction [Vincristine results in increased expression of ABCB1 protein]; Verapamil inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]; zosuquidar trihydrochloride inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine] ABCB1 protein results in decreased uptake of Vincristine ABCB1 protein affects the uptake of Vincristine |
CTD |
PMID:7905786 PMID:10617675 PMID:11792417 PMID:11934808 PMID:15239124 PMID:15645438 PMID:16038730 PMID:16221289 PMID:16316932 PMID:16925584 PMID:19944135 PMID:20041327 PMID:21344920 PMID:21833476 PMID:25058526 |
|
NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
|
|
G |
Abcb1b |
ATP-binding cassette, subfamily B (MDR/TAP), member 1B |
affects uptake |
EXP |
ABCB1B protein affects the uptake of Vincristine |
CTD |
PMID:11934808 |
|
NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
|
|
G |
Abcb4 |
ATP binding cassette subfamily B member 4 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCB4 mRNA |
CTD |
PMID:19944135 |
|
NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
|
|
G |
Abcb6 |
ATP binding cassette subfamily B member 6 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCB6 mRNA |
CTD |
PMID:19944135 |
|
NCBI chr 9:82,373,950...82,382,228
Ensembl chr 9:82,373,946...82,382,272
|
|
G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
increases response to substance increases expression multiple interactions decreases response to substance affects transport affects response to substance affects export |
ISO EXP |
ABCC1 gene SNP results in increased susceptibility to Vincristine Vincristine results in increased expression of ABCC1 mRNA [Genistein results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine; [Indomethacin results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine; [Probenecid results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine; [Sulfinpyrazone results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine; [verlukast results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine ABCC1 protein results in decreased susceptibility to Vincristine; ABCC1 results in decreased susceptibility to Vincristine [MYCN protein affects the expression of ABCC1 mRNA] which affects the susceptibility to Vincristine; [Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCC1 mRNA; ABCC1 protein affects the export of and results in decreased susceptibility to Vincristine; Buthionine Sulfoximine inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; Cyclosporine inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; Doxorubicin inhibits the reaction [ABCC1 protein affects the transport of Vincristine]; GSTP1 protein promotes the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; myricetin inhibits the reaction [ABCC1 protein affects the export of and results in decreased susceptibility to Vincristine]; myricetin inhibits the reaction [ABCC1 protein affects the export of Vincristine]; myricetin inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; Quercetin promotes the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; Verapamil inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; verlukast inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; Vincristine inhibits the reaction [ABCC1 protein affects the transport of fluorexon]; Vincristine inhibits the reaction [Glutathione promotes the reaction [ABCC1 results in increased transport of methylarsine analog]]; zafirlukast inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine] ABCC1 protein affects the transport of Vincristine; ABCC1 protein mutant form affects the transport of Vincristine ABCC1 protein affects the susceptibility to Vincristine |
CTD |
PMID:7954421 PMID:8649356 PMID:8968083 PMID:10348353 PMID:10685512 PMID:10900222 PMID:11278867 PMID:11306701 PMID:11778547 PMID:12067707 PMID:12731862 PMID:12893836 PMID:15044619 PMID:15180633 PMID:15581632 PMID:15896345 PMID:16042792 PMID:16221289 PMID:19232821 PMID:19944135 PMID:20864405 PMID:21918036 PMID:22095822 |
|
NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
|
|
G |
Abcc10 |
ATP binding cassette subfamily C member 10 |
multiple interactions decreases response to substance |
ISO |
4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide inhibits the reaction [ABCC10 protein results in decreased susceptibility to Vincristine]; Imatinib Mesylate inhibits the reaction [ABCC10 protein results in decreased susceptibility to Vincristine] |
CTD |
PMID:19841739 |
|
NCBI chr 9:17,041,351...17,061,263
Ensembl chr 9:17,041,389...17,063,780
|
|
G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
affects export multiple interactions decreases response to substance |
ISO |
ABCC2 protein affects the export of Vincristine [Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCC2 mRNA; ABCC2 protein affects the export of and results in decreased susceptibility to Vincristine; myricetin inhibits the reaction [ABCC2 protein affects the export of and results in decreased susceptibility to Vincristine]; myricetin inhibits the reaction [ABCC2 protein affects the export of Vincristine]; myricetin inhibits the reaction [ABCC2 protein results in decreased susceptibility to Vincristine] |
CTD |
PMID:15896345 PMID:19944135 PMID:22095822 |
|
NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
|
|
G |
Abcc3 |
ATP binding cassette subfamily C member 3 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCC3 mRNA |
CTD |
PMID:19944135 |
|
NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
|
|
G |
Abcc4 |
ATP binding cassette subfamily C member 4 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which results in decreased expression of ABCC4 mRNA |
CTD |
PMID:19944135 |
|
NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
|
|
G |
Abcc5 |
ATP binding cassette subfamily C member 5 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCC5 mRNA |
CTD |
PMID:19944135 |
|
NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
|
|
G |
Abcc6 |
ATP binding cassette subfamily C member 6 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which results in decreased expression of ABCC6 mRNA |
CTD |
PMID:19944135 |
|
NCBI chr 1:101,954,786...102,013,252
Ensembl chr 1:101,959,540...102,013,243
|
|
G |
Abcd3 |
ATP binding cassette subfamily D member 3 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which results in decreased expression of ABCD3 mRNA |
CTD |
PMID:19944135 |
|
NCBI chr 2:225,335,708...225,389,120
Ensembl chr 2:225,335,718...225,389,120
|
|
G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which results in decreased expression of ABCG1 mRNA |
CTD |
PMID:19944135 |
|
NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489
|
|
G |
Abcg2 |
ATP binding cassette subfamily G member 2 |
multiple interactions |
ISO |
[Paclitaxel results in decreased expression of ABCG2] which results in decreased susceptibility to Vincristine; [Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCG2 mRNA |
CTD |
PMID:19944135 PMID:21833476 |
|
NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
|
|
G |
Abcg4 |
ATP binding cassette subfamily G member 4 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which results in decreased expression of ABCG4 mRNA |
CTD |
PMID:19944135 |
|
NCBI chr 8:48,604,915...48,626,219
Ensembl chr 8:48,606,403...48,619,592
|
|
G |
Abhd11 |
abhydrolase domain containing 11 |
decreases expression |
ISO |
Vincristine results in decreased expression of ABHD11 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr12:24,722,277...24,725,760
Ensembl chr12:24,722,283...24,724,997
|
|
G |
Abtb2 |
ankyrin repeat and BTB domain containing 2 |
increases expression |
ISO |
Vincristine results in increased expression of ABTB2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:93,494,706...93,648,750
Ensembl chr 3:93,495,106...93,647,721
|
|
G |
Acad9 |
acyl-CoA dehydrogenase family, member 9 |
decreases expression |
ISO |
Vincristine results in decreased expression of ACAD9 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:122,782,051...122,806,166
Ensembl chr 2:122,782,060...122,805,768
|
|
G |
Ache |
acetylcholinesterase |
decreases expression multiple interactions |
EXP |
Vincristine results in decreased expression of ACHE protein xaliproden inhibits the reaction [Vincristine results in decreased expression of ACHE protein] |
CTD |
PMID:8413926 |
|
NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
|
|
G |
Ackr3 |
atypical chemokine receptor 3 |
increases expression |
ISO |
Vincristine results in increased expression of ACKR3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:97,355,881...97,367,455
Ensembl chr 9:97,355,924...97,367,445
|
|
G |
Actr2 |
actin related protein 2 |
increases expression |
ISO |
Vincristine results in increased expression of ACTR2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:104,338,486...104,375,840
Ensembl chr14:104,340,434...104,375,649
|
|
G |
Adat2 |
adenosine deaminase, tRNA-specific 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of ADAT2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:7,726,447...7,743,112
Ensembl chr 1:7,726,529...7,742,484
|
|
G |
Adgrf4 |
adhesion G protein-coupled receptor F4 |
increases expression |
ISO |
Vincristine results in increased expression of ADGRF4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:20,951,249...20,982,493
Ensembl chr 9:20,951,260...20,982,487
|
|
G |
Adrb1 |
adrenoceptor beta 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of ADRB1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
|
|
G |
Adrb2 |
adrenoceptor beta 2 |
increases response to substance |
ISO |
ADRB2 gene SNP results in increased susceptibility to Vincristine |
CTD |
PMID:21245421 |
|
NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
|
|
G |
Agbl3 |
AGBL carboxypeptidase 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of AGBL3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:62,293,158...62,377,740
Ensembl chr 4:62,299,044...62,376,533
|
|
G |
Ahsa2 |
activator of HSP90 ATPase homolog 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of AHSA2P mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:108,262,795...108,274,000
Ensembl chr14:108,265,207...108,273,938
|
|
G |
Aim2 |
absent in melanoma 2 |
increases expression |
ISO |
Vincristine results in increased expression of AIM2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:91,919,834...91,963,080
Ensembl chr13:91,954,138...91,962,588
|
|
G |
Ak1 |
adenylate kinase 1 |
decreases expression |
EXP |
Vincristine results in decreased expression of AK1 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 3:11,652,143...11,659,135
|
|
G |
Ak3 |
adenylate kinase 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of AK3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:247,144,486...247,169,690
Ensembl chr 1:247,144,491...247,169,693
|
|
G |
Akap10 |
A-kinase anchoring protein 10 |
increases expression |
ISO |
Vincristine results in increased expression of AKAP10 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:48,150,902...48,210,074
Ensembl chr10:48,150,902...48,210,074
|
|
G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
ISO |
Vincristine inhibits the reaction [Doxorubicin results in decreased phosphorylation of AKT1 protein] Vincristine promotes the reaction [NVP ADW742 inhibits the reaction [IGF1 protein results in increased phosphorylation of AKT1 protein]] |
CTD |
PMID:16740780 PMID:18590705 |
|
NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
|
|
G |
Aldoc |
aldolase, fructose-bisphosphate C |
decreases expression |
ISO |
Vincristine results in decreased expression of ALDOC mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
|
|
G |
Alms1 |
ALMS1, centrosome and basal body associated protein |
decreases expression |
ISO |
Vincristine results in decreased expression of ALMS1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:117,371,544...117,472,310
Ensembl chr 4:117,371,659...117,472,198
|
|
G |
Alpk2 |
alpha-kinase 2 |
increases expression |
ISO |
Vincristine results in increased expression of ALPK2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr18:60,960,009...61,072,116
Ensembl chr18:60,960,662...61,057,365
|
|
G |
Amh |
anti-Mullerian hormone |
decreases secretion |
ISO |
Vincristine results in decreased secretion of AMH protein |
CTD |
PMID:30657998 |
|
NCBI chr 7:11,775,155...11,777,503
Ensembl chr 7:11,775,155...11,777,503
|
|
G |
Anapc5 |
anaphase-promoting complex subunit 5 |
increases expression |
ISO |
Vincristine results in increased expression of ANAPC5 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr12:39,209,134...39,242,696
Ensembl chr12:39,209,129...39,242,690
|
|
G |
Ankdd1a |
ankyrin repeat and death domain containing 1A |
decreases expression |
ISO |
Vincristine results in decreased expression of ANKDD1A mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:71,034,630...71,057,265
Ensembl chr 8:71,035,309...71,055,969
|
|
G |
Ankhd1 |
ankyrin repeat and KH domain containing 1 |
increases expression |
ISO |
Vincristine results in increased expression of ANKHD1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr18:29,386,906...29,485,611
Ensembl chr18:29,386,809...29,492,718
|
|
G |
Ankra2 |
ankyrin repeat family A member 2 |
increases expression |
ISO |
Vincristine results in increased expression of ANKRA2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:82,407,601...82,418,229
Ensembl chr X:82,407,598...82,418,425
|
|
G |
Ankrd13c |
ankyrin repeat domain 13C |
decreases expression |
ISO |
Vincristine results in decreased expression of ANKRD13C mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:264,785,379...264,833,283
Ensembl chr 2:264,786,242...264,833,283
|
|
G |
Ankrd33b |
ankyrin repeat domain 33B |
increases expression |
ISO |
Vincristine results in increased expression of ANKRD33B mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:84,361,061...84,436,912
Ensembl chr 2:84,361,061...84,437,084
|
|
G |
Ankrd37 |
ankyrin repeat domain 37 |
decreases expression |
ISO |
Vincristine results in decreased expression of ANKRD37 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr16:49,463,016...49,465,905
Ensembl chr16:49,462,889...49,465,888
|
|
G |
Anp32e |
acidic nuclear phosphoprotein 32 family member E |
decreases expression |
ISO |
Vincristine results in decreased expression of ANP32E mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:198,040,573...198,057,005
Ensembl chr 2:198,040,536...198,057,003
|
|
G |
Anxa1 |
annexin A1 |
increases expression |
ISO |
Vincristine results in increased expression of ANXA1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
|
|
G |
Anxa2 |
annexin A2 |
increases expression |
ISO |
Vincristine results in increased expression of ANXA2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
|
|
G |
Ap1s2 |
adaptor related protein complex 1 subunit sigma 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of AP1S2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:32,329,883...32,376,301
Ensembl chr X:32,329,598...32,355,307
|
|
G |
Apex2 |
apurinic/apyrimidinic endodeoxyribonuclease 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of APEX2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:23,146,085...23,166,676
Ensembl chr X:23,146,085...23,166,675
|
|
G |
Apln |
apelin |
decreases expression |
EXP |
Vincristine results in decreased expression of APLN mRNA |
CTD |
PMID:20624997 |
|
NCBI chr X:134,856,719...134,866,210
Ensembl chr X:134,856,726...134,866,210
|
|
G |
Apod |
apolipoprotein D |
increases expression |
ISO |
Vincristine results in increased expression of APOD mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:72,705,204...72,726,263
Ensembl chr11:72,705,129...72,726,301
|
|
G |
Apold1 |
apolipoprotein L domain containing 1 |
increases expression |
ISO |
Vincristine results in increased expression of APOLD1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:168,752,142...168,755,024
Ensembl chr 4:168,752,133...168,755,023
|
|
G |
Aqp9 |
aquaporin 9 |
increases expression |
ISO |
Vincristine results in increased expression of AQP9 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:77,559,621...77,599,781
Ensembl chr 8:77,559,624...77,599,781
|
|
G |
Arap2 |
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of ARAP2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:48,726,033...48,922,809
Ensembl chr14:48,726,045...48,922,983
|
|
G |
Arf1 |
ADP-ribosylation factor 1 |
increases expression |
ISO |
Vincristine results in increased expression of ARF1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:45,562,700...45,579,214
Ensembl chr10:45,563,547...45,579,029
|
|
G |
Arhgap15 |
Rho GTPase activating protein 15 |
increases expression |
ISO |
Vincristine results in increased expression of ARHGAP15 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:28,626,987...29,236,225
Ensembl chr 3:28,627,084...29,236,219
|
|
G |
Arhgap18 |
Rho GTPase activating protein 18 |
decreases expression |
ISO |
Vincristine results in decreased expression of ARHGAP18 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:19,227,115...19,463,139
Ensembl chr 1:19,227,121...19,376,301
|
|
G |
Arhgap5 |
Rho GTPase activating protein 5 |
decreases expression |
ISO |
Vincristine results in decreased expression of ARHGAP5 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:73,345,129...73,408,304
Ensembl chr 6:73,345,392...73,405,880
|
|
G |
Arhgef6 |
Rac/Cdc42 guanine nucleotide exchange factor 6 |
increases expression |
ISO |
Vincristine results in increased expression of ARHGEF6 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:159,722,031...159,841,344
Ensembl chr X:159,723,866...159,841,072
|
|
G |
Arhgef7 |
Rho guanine nucleotide exchange factor 7 |
increases expression |
ISO |
Vincristine results in increased expression of ARHGEF7 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr16:83,006,732...83,117,065
Ensembl chr16:83,006,718...83,132,785
|
|
G |
Arid2 |
AT-rich interaction domain 2 |
increases expression |
ISO |
Vincristine results in increased expression of ARID2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:137,680,564...137,798,329
Ensembl chr 7:137,680,530...137,795,655
|
|
G |
Arid4b |
AT-rich interaction domain 4B |
increases expression |
ISO |
Vincristine results in increased expression of ARID4B mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:53,831,353...53,955,897
Ensembl chr17:53,833,023...53,915,076
|
|
G |
Arl5a |
ADP-ribosylation factor like GTPase 5A |
decreases expression |
ISO |
Vincristine results in decreased expression of ARL5A mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:37,922,544...37,947,434
Ensembl chr 3:37,924,793...37,947,283
|
|
G |
Arl5b |
ADP-ribosylation factor like GTPase 5B |
increases expression |
ISO |
Vincristine results in increased expression of ARL5B mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:82,065,893...82,092,693
Ensembl chr17:82,065,937...82,091,362
|
|
G |
Arl6ip1 |
ADP-ribosylation factor like GTPase 6 interacting protein 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of ARL6IP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:187,770,160...187,779,675
Ensembl chr 1:187,770,160...187,779,675
|
|
G |
Armc8 |
armadillo repeat containing 8 |
decreases expression |
ISO |
Vincristine results in decreased expression of ARMC8 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:107,723,359...107,819,208
Ensembl chr 8:107,723,359...107,819,050
|
|
G |
Aspm |
assembly factor for spindle microtubules |
increases expression |
ISO |
Vincristine results in increased expression of ASPM mRNA |
CTD |
PMID:17374387 |
|
NCBI chr13:56,546,021...56,591,793
Ensembl chr13:56,546,021...56,591,793
|
|
G |
Asxl1 |
ASXL transcriptional regulator 1 |
increases expression |
ISO |
Vincristine results in increased expression of ASXL1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:148,832,231...148,902,356
Ensembl chr 3:148,837,814...148,900,452
|
|
G |
Atad2 |
ATPase family, AAA domain containing 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of ATAD2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:97,984,754...98,027,379
Ensembl chr 7:97,984,862...98,026,052
|
|
G |
Atf3 |
activating transcription factor 3 |
increases expression |
ISO |
Vincristine results in increased expression of ATF3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
|
|
G |
Atf5 |
activating transcription factor 5 |
increases expression |
ISO |
Vincristine results in increased expression of ATF5 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:100,807,821...100,812,410
Ensembl chr 1:100,808,241...100,810,522
|
|
G |
Atp2b4 |
ATPase plasma membrane Ca2+ transporting 4 |
increases expression |
ISO |
Vincristine results in increased expression of ATP2B4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823
|
|
G |
Atp5f1c |
ATP synthase F1 subunit gamma |
decreases expression |
ISO |
Vincristine results in decreased expression of ATP5F1C mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:72,209,321...72,231,562
Ensembl chr17:72,209,373...72,394,271
|
|
G |
Atp6v0e1 |
ATPase H+ transporting V0 subunit e1 |
increases expression |
ISO |
Vincristine results in increased expression of ATP6V0E1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:16,769,857...16,792,930
Ensembl chr10:16,769,666...16,792,909
|
|
G |
Atp7a |
ATPase copper transporting alpha |
decreases response to substance |
ISO |
ATP7A protein results in decreased susceptibility to Vincristine |
CTD |
PMID:17510416 |
|
NCBI chr X:77,076,085...77,193,644
Ensembl chr X:77,076,106...77,193,644
|
|
G |
Atp8a1 |
ATPase phospholipid transporting 8A1 |
decreases expression |
ISO |
Vincristine results in decreased expression of ATP8A1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:41,972,398...42,210,555
Ensembl chr14:42,015,347...42,206,311
|
|
G |
Aurka |
aurora kinase A |
increases response to substance increases expression |
ISO |
AURKA gene SNP results in increased susceptibility to Vincristine Vincristine results in increased expression of AURKA mRNA |
CTD |
PMID:17374387 PMID:20864405 |
|
NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210
|
|
G |
Aurkb |
aurora kinase B |
decreases expression |
ISO |
Vincristine results in decreased expression of AURKB mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
|
|
G |
Avp |
arginine vasopressin |
increases expression |
ISO |
Vincristine results in increased expression of AVP protein |
CTD |
PMID:4356234 |
|
NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
|
|
G |
B3galt6 |
Beta-1,3-galactosyltransferase 6 |
decreases expression |
ISO |
Vincristine results in decreased expression of B3GALT6 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:173,423,475...173,425,611
Ensembl chr 5:173,423,475...173,425,611
|
|
G |
B3gnt5 |
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 |
increases expression |
ISO |
Vincristine results in increased expression of B3GNT5 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:84,919,055...84,931,160
Ensembl chr11:84,919,066...84,931,160
|
|
G |
Bak1 |
BCL2-antagonist/killer 1 |
affects response to substance |
ISO |
BAK1 protein affects the susceptibility to Vincristine |
CTD |
PMID:22178383 |
|
NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
|
|
G |
Bambi |
BMP and activin membrane-bound inhibitor |
increases expression |
ISO |
Vincristine results in increased expression of BAMBI mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:56,905,419...56,909,675
Ensembl chr17:56,905,112...56,909,992
|
|
G |
Bard1 |
BRCA1 associated RING domain 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of BARD1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:78,297,723...78,368,777
Ensembl chr 9:78,294,834...78,369,031
|
|
G |
Basp1 |
brain abundant, membrane attached signal protein 1 |
increases expression |
ISO |
Vincristine results in increased expression of BASP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:77,586,424...77,632,626
Ensembl chr 2:77,586,424...77,632,628
|
|
G |
Batf |
basic leucine zipper ATF-like transcription factor |
increases expression |
ISO |
Vincristine results in increased expression of BATF mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:109,562,415...109,584,541
Ensembl chr 6:109,562,587...109,584,545
|
|
G |
Bax |
BCL2 associated X, apoptosis regulator |
decreases expression affects response to substance multiple interactions |
ISO |
Vincristine results in decreased expression of BAX mRNA BAX protein affects the susceptibility to Vincristine [Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of BAX protein; Vincristine results in increased cleavage of and results in increased expression of BAX protein |
CTD |
PMID:9815696 PMID:15131059 PMID:16001973 PMID:22178383 |
|
NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
|
|
G |
Bcat1 |
branched chain amino acid transaminase 1 |
increases expression |
ISO |
Vincristine results in increased expression of BCAT1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:179,259,305...179,340,021
Ensembl chr 4:179,259,308...179,339,795
|
|
G |
Bcl2 |
BCL2, apoptosis regulator |
decreases response to substance increases phosphorylation multiple interactions |
ISO |
BCL2 protein results in decreased susceptibility to Vincristine Vincristine results in increased phosphorylation of BCL2 protein [Doxorubicin co-treated with Dexamethasone co-treated with Vincristine co-treated with Cytarabine co-treated with Mercaptopurine co-treated with Methotrexate co-treated with Cyclophosphamide co-treated with Enzymes and Coenzymes] results in increased expression of BCL2 protein; [Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of BCL2 protein; [MIR497 results in decreased expression of BCL2 protein] which results in increased susceptibility to Vincristine; TYMP inhibits the reaction [Vincristine results in increased phosphorylation of BCL2 protein] |
CTD |
PMID:9815696 PMID:15907805 PMID:20162574 PMID:21182165 PMID:21258880 |
|
NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
|
|
G |
Bcl2a1 |
BCL2-related protein A1 |
increases expression |
ISO |
Vincristine results in increased expression of BCL2A1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
|
|
G |
Bcl2l1 |
Bcl2-like 1 |
increases expression affects response to substance |
ISO |
Vincristine results in increased expression of BCL2L1 mRNA BCL2L1 protein affects the susceptibility to Vincristine |
CTD |
PMID:22178383 PMID:23649840 |
|
NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
|
|
G |
Bclaf1 |
BCL2-associated transcription factor 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of BCLAF1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:15,799,753...15,828,838
Ensembl chr 1:15,782,477...15,860,624
|
|
G |
Bcor |
BCL6 co-repressor |
increases expression |
ISO |
Vincristine results in increased expression of BCOR mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:11,570,155...11,692,022
Ensembl chr X:11,648,989...11,691,099
|
|
G |
Bdkrb1 |
bradykinin receptor B1 |
multiple interactions |
EXP |
[HOE 140, desArg(10)- binds to and results in decreased activity of BDKRB1 protein] which results in decreased susceptibility to Vincristine |
CTD |
PMID:17989505 |
|
NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
|
|
G |
Bdkrb2 |
bradykinin receptor B2 |
multiple interactions |
EXP |
[icatibant binds to and results in decreased activity of BDKRB2 protein] which results in decreased susceptibility to Vincristine |
CTD |
PMID:17989505 |
|
NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
|
|
G |
Birc2 |
baculoviral IAP repeat-containing 2 |
increases expression |
ISO |
Vincristine results in increased expression of BIRC2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
|
|
G |
Birc3 |
baculoviral IAP repeat-containing 3 |
increases expression |
ISO |
Vincristine results in increased expression of BIRC3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
|
|
G |
Blm |
BLM RecQ like helicase |
decreases expression |
ISO |
Vincristine results in decreased expression of BLM mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:142,246,773...142,332,616
Ensembl chr 1:142,246,790...142,332,588
|
|
G |
Bmp2 |
bone morphogenetic protein 2 |
increases expression |
ISO |
Vincristine results in increased expression of BMP2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
|
|
G |
Bnip3 |
BCL2 interacting protein 3 |
decreases expression multiple interactions |
ISO |
Vincristine results in decreased expression of BNIP3 mRNA Vincristine affects the reaction [Valproic Acid affects the localization of BNIP3 protein] |
CTD |
PMID:23649840 PMID:25446377 |
|
NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
|
|
G |
Bnip3l |
BCL2 interacting protein 3 like |
decreases expression |
ISO |
Vincristine results in decreased expression of BNIP3L mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029
|
|
G |
Borcs7 |
BLOC-1 related complex subunit 7 |
increases expression |
ISO |
Vincristine results in increased expression of BORCS7 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:266,451,021...266,464,903
Ensembl chr 1:266,451,021...266,464,903
|
|
G |
Brip1 |
BRCA1 interacting protein C-terminal helicase 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of BRIP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:73,507,009...73,632,742
Ensembl chr10:73,507,100...73,629,581
|
|
G |
Brwd1 |
bromodomain and WD repeat domain containing 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of BRWD1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:36,338,080...36,430,473
Ensembl chr11:36,337,635...36,430,413
|
|
G |
Btg1 |
BTG anti-proliferation factor 1 |
increases expression |
ISO |
Vincristine results in increased expression of BTG1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:37,812,831...37,815,088
Ensembl chr 7:37,812,831...37,815,088
|
|
G |
Btg2 |
BTG anti-proliferation factor 2 |
increases expression |
ISO |
Vincristine results in increased expression of BTG2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
|
|
G |
Btg4 |
BTG anti-proliferation factor 4 |
increases expression |
ISO |
Vincristine results in increased expression of BTG4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:55,408,917...55,508,100
Ensembl chr 8:55,504,359...55,508,259
|
|
G |
Bub3 |
BUB3 mitotic checkpoint protein |
decreases expression |
ISO |
Vincristine results in decreased expression of BUB3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:203,526,853...203,537,459
Ensembl chr 1:203,524,426...203,557,337
|
|
G |
C1galt1 |
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of C1GALT1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:33,890,353...33,943,219
Ensembl chr 4:33,890,349...33,943,211
|
|
G |
Cables2 |
Cdk5 and Abl enzyme substrate 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of CABLES2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:175,630,266...175,644,994
Ensembl chr 3:175,631,881...175,644,988
|
|
G |
Cacnb2 |
calcium voltage-gated channel auxiliary subunit beta 2 |
increases expression |
ISO |
Vincristine results in increased expression of CACNB2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:81,673,862...82,019,219
Ensembl chr17:81,798,756...82,017,682
|
|
G |
Cald1 |
caldesmon 1 |
increases expression |
ISO |
Vincristine results in increased expression of CALD1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:62,103,948...62,291,375
Ensembl chr 4:62,220,736...62,291,489
|
|
G |
Calm2 |
calmodulin 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of CALM2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968
|
|
G |
Calu |
calumenin |
increases expression |
ISO |
Vincristine results in increased expression of CALU mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:56,625,611...56,653,112
Ensembl chr 4:56,625,561...56,653,111
|
|
G |
Camk2d |
calcium/calmodulin-dependent protein kinase II delta |
decreases expression |
ISO |
Vincristine results in decreased expression of CAMK2D mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:230,900,907...231,132,207
Ensembl chr 2:230,901,126...231,132,039
|
|
G |
Camkk1 |
calcium/calmodulin-dependent protein kinase kinase 1 |
increases response to substance |
ISO |
CAMKK1 gene SNP results in increased susceptibility to Vincristine |
CTD |
PMID:21245421 |
|
NCBI chr10:59,585,023...59,608,180
Ensembl chr10:59,585,072...59,608,165
|
|
G |
Capg |
capping actin protein, gelsolin like |
increases expression |
ISO |
Vincristine results in increased expression of CAPG mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:100,395,693...100,419,447
Ensembl chr 4:100,407,658...100,419,446
|
|
G |
Carhsp1 |
calcium regulated heat stable protein 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of CARHSP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:7,041,510...7,055,107
Ensembl chr10:7,041,510...7,055,101
|
|
G |
Casp1 |
caspase 1 |
increases expression |
ISO |
Vincristine results in increased expression of CASP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
|
|
G |
Casp3 |
caspase 3 |
increases cleavage multiple interactions increases expression |
EXP |
Vincristine results in increased cleavage of CASP3 protein Sumatriptan inhibits the reaction [Vincristine results in increased expression of CASP3 mRNA]; Sumatriptan inhibits the reaction [Vincristine results in increased expression of CASP3 protein] Vincristine results in increased expression of CASP3 mRNA; Vincristine results in increased expression of CASP3 protein |
CTD |
PMID:20624997 PMID:29958920 |
|
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
|
|
G |
Casp6 |
caspase 6 |
increases expression |
ISO |
Vincristine results in increased expression of CASP6 mRNA |
CTD |
PMID:16001973 |
|
NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967 Ensembl chr 2:235,341,365...235,353,967
|
|
G |
Casp8 |
caspase 8 |
increases expression increases response to substance multiple interactions |
ISO |
Vincristine results in increased expression of CASP8 mRNA CASP8 protein results in increased susceptibility to Vincristine Vincristine results in increased expression of and results in increased cleavage of CASP8 protein |
CTD |
PMID:16001973 PMID:22010212 |
|
NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
|
|
G |
Cat |
catalase |
affects response to substance decreases expression multiple interactions |
ISO EXP |
CAT protein affects the susceptibility to Vincristine Vincristine results in decreased expression of CAT protein tetrahydrocurcumin inhibits the reaction [Vincristine results in decreased expression of CAT protein]; Vincristine inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Vincristine inhibits the reaction [Isoproterenol results in decreased expression of CAT protein] |
CTD |
PMID:11178967 PMID:24201307 PMID:25537132 PMID:26102012 |
|
NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
|
|
G |
Cbx3 |
chromobox 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of CBX3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:81,243,809...81,257,898
Ensembl chr 4:81,244,469...81,257,897
|
|
G |
Cbx5 |
chromobox 5 |
decreases expression |
ISO |
Vincristine results in decreased expression of CBX5 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:144,819,673...144,865,014
Ensembl chr 7:144,819,420...144,837,583
|
|
G |
Ccar1 |
cell division cycle and apoptosis regulator 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of CCAR1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr20:32,373,443...32,416,044
Ensembl chr20:32,373,443...32,416,044
|
|
G |
Ccdc12 |
coiled-coil domain containing 12 |
decreases expression |
ISO |
Vincristine results in decreased expression of CCDC12 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:118,925,682...118,977,038
Ensembl chr 8:118,926,478...118,977,051
|
|
G |
Ccdc186 |
coiled-coil domain containing 186 |
decreases expression |
ISO |
Vincristine results in decreased expression of CCDC186 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:277,603,601...277,635,379
Ensembl chr 1:277,606,995...277,629,196
|
|
G |
Ccdc198 |
coiled-coil domain containing 198 |
decreases expression |
ISO |
Vincristine results in decreased expression of CCDC198 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:26,090,458...26,106,523
|
|
G |
Ccdc32 |
coiled-coil domain containing 32 |
decreases expression |
ISO |
Vincristine results in decreased expression of CCDC32 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:110,816,327...110,828,824
Ensembl chr 3:110,816,337...110,828,879
|
|
G |
Ccdc82 |
coiled-coil domain containing 82 |
increases expression |
ISO |
Vincristine results in increased expression of CCDC82 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:11,888,460...11,927,920
Ensembl chr 8:11,888,591...11,927,919
|
|
G |
Cchcr1 |
coiled-coil alpha-helical rod protein 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of CCHCR1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr20:3,730,968...3,745,721
Ensembl chr20:3,730,955...3,740,009
|
|
G |
Ccl1 |
C-C motif chemokine ligand 1 |
increases expression |
ISO |
Vincristine results in increased expression of CCL1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:69,534,976...69,537,836
Ensembl chr10:69,534,933...69,537,882
|
|
G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases expression |
ISO EXP |
Vincristine results in increased expression of CCL2 mRNA |
CTD |
PMID:20624997 PMID:23649840 |
|
NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
|
|
G |
Ccl20 |
C-C motif chemokine ligand 20 |
increases expression |
ISO |
Vincristine results in increased expression of CCL20 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
|
|
G |
Ccl22 |
C-C motif chemokine ligand 22 |
increases expression |
ISO |
Vincristine results in increased expression of CCL22 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr19:10,674,189...10,681,145
Ensembl chr19:10,674,189...10,681,145
|
|
G |
Ccl4 |
C-C motif chemokine ligand 4 |
increases expression |
ISO |
Vincristine results in increased expression of CCL4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
|
|
G |
Ccl5 |
C-C motif chemokine ligand 5 |
increases expression |
ISO |
Vincristine results in increased expression of CCL5 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
|
|
G |
Ccn2 |
cellular communication network factor 2 |
decreases response to substance |
ISO |
CCN2 mRNA results in decreased susceptibility to Vincristine |
CTD |
PMID:24154679 |
|
NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
|
|
G |
Ccnb1 |
cyclin B1 |
affects response to substance increases expression |
ISO |
CCNB1 protein affects the susceptibility to Vincristine Vincristine results in increased expression of CCNB1 mRNA |
CTD |
PMID:22178383 PMID:23649840 |
|
NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
|
|
G |
Ccnb2 |
cyclin B2 |
increases expression |
ISO |
Vincristine results in increased expression of CCNB2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:76,847,972...76,861,165
|
|
G |
Ccne1 |
cyclin E1 |
decreases expression |
ISO |
Vincristine results in decreased expression of CCNE1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
|
|
G |
Ccne2 |
cyclin E2 |
decreases expression |
ISO |
Vincristine results in decreased expression of CCNE2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
|
|
G |
Ccnl1 |
cyclin L1 |
decreases expression |
ISO |
Vincristine results in decreased expression of CCNL1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:157,747,295...157,759,838
Ensembl chr 2:157,747,542...157,759,838
|
|
G |
Cd109 |
CD109 molecule |
increases expression |
ISO |
Vincristine results in increased expression of CD109 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:85,951,420...86,065,411
Ensembl chr 8:85,951,191...86,065,409
|
|
G |
Cd14 |
CD14 molecule |
increases expression |
EXP |
Vincristine results in increased expression of CD14 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
|
|
G |
Cd200 |
Cd200 molecule |
increases expression |
ISO |
Vincristine results in increased expression of CD200 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:60,371,617...60,398,450
Ensembl chr11:60,371,684...60,403,196
|
|
G |
Cd274 |
CD274 molecule |
increases expression |
ISO |
Vincristine results in increased expression of CD274 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:247,519,890...247,539,659
Ensembl chr 1:247,519,939...247,537,943
|
|
G |
Cd36 |
CD36 molecule |
increases expression |
EXP |
Vincristine results in increased expression of CD36 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
|
|
G |
Cd40 |
CD40 molecule |
increases expression |
ISO |
Vincristine results in increased expression of CD40 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
|
|
G |
Cd44 |
CD44 molecule (Indian blood group) |
increases expression |
ISO |
Vincristine results in increased expression of CD44 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
|
|
G |
Cd48 |
Cd48 molecule |
increases expression |
ISO |
Vincristine results in increased expression of CD48 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:90,116,601...90,140,371
Ensembl chr13:90,116,843...90,140,371
|
|
G |
Cd55 |
CD55 molecule (Cromer blood group) |
increases expression |
ISO |
Vincristine results in increased expression of CD55 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:47,125,156...47,153,557
Ensembl chr13:47,126,741...47,154,292
|
|
G |
Cd69 |
Cd69 molecule |
increases expression |
ISO |
Vincristine results in increased expression of CD69 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:163,041,147...163,049,065
Ensembl chr 4:163,041,141...163,049,084
|
|
G |
Cd80 |
Cd80 molecule |
increases expression |
ISO |
Vincristine results in increased expression of CD80 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:64,815,201...64,855,293
Ensembl chr11:64,827,635...64,855,353
|
|
G |
Cd83 |
CD83 molecule |
increases expression |
ISO |
Vincristine results in increased expression of CD83 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:24,416,651...24,435,790
Ensembl chr17:24,416,651...24,435,790
|
|
G |
Cd86 |
CD86 molecule |
increases expression |
ISO |
Vincristine results in increased expression of CD86 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
|
|
G |
Cdc42ep3 |
CDC42 effector protein 3 |
increases expression |
ISO |
Vincristine results in increased expression of CDC42EP3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:1,922,500...1,942,972
Ensembl chr 6:1,922,500...1,942,972
|
|
G |
Cdc42ep4 |
CDC42 effector protein 4 |
increases expression |
ISO |
Vincristine results in increased expression of CDC42EP4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:102,244,680...102,269,272
Ensembl chr10:102,244,681...102,269,272
|
|
G |
Cdc42se1 |
CDC42 small effector 1 |
increases expression |
ISO |
Vincristine results in increased expression of CDC42SE1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:196,402,837...196,410,664
Ensembl chr 2:196,402,837...196,410,659
|
|
G |
Cdc6 |
cell division cycle 6 |
decreases expression |
ISO |
Vincristine results in decreased expression of CDC6 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:86,819,477...86,833,301
Ensembl chr10:86,819,472...86,833,402
|
|
G |
Cdca3 |
cell division cycle associated 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of CDCA3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:157,347,876...157,351,889
Ensembl chr 4:157,348,020...157,351,604
|
|
G |
Cdca7 |
cell division cycle associated 7 |
decreases expression |
ISO |
Vincristine results in decreased expression of CDCA7 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:59,153,281...59,163,916
Ensembl chr 3:59,153,280...59,163,913
|
|
G |
Cdh1 |
cadherin 1 |
increases expression |
ISO |
Vincristine results in increased expression of CDH1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
|
|
G |
Cdk1 |
cyclin-dependent kinase 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of CDK1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
|
|
G |
Cdk10 |
cyclin-dependent kinase 10 |
decreases expression |
ISO |
Vincristine results in decreased expression of CDK10 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr19:56,024,903...56,032,610
Ensembl chr19:56,024,903...56,032,605
|
|
G |
Cdk19 |
cyclin-dependent kinase 19 |
decreases expression |
ISO |
Vincristine results in decreased expression of CDK19 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr20:45,458,499...45,598,799
Ensembl chr20:45,458,558...45,598,798
|
|
G |
Cdk2 |
cyclin dependent kinase 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of CDK2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
|
|
G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression multiple interactions |
EXP ISO |
Vincristine results in increased expression of CDKN1A mRNA resveratrol inhibits the reaction [Vincristine results in increased expression of CDKN1A mRNA] |
CTD |
PMID:20624997 PMID:23649840 PMID:26055805 |
|
NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
|
|
G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
increases response to substance |
ISO |
CDKN2A protein results in increased susceptibility to Vincristine |
CTD |
PMID:16786135 |
|
NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
|
|
G |
Cdkn2c |
cyclin-dependent kinase inhibitor 2C |
decreases expression |
ISO |
Vincristine results in decreased expression of CDKN2C mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:129,347,731...129,352,886
Ensembl chr 5:129,347,732...129,352,886
|
|
G |
Ceacam1 |
CEA cell adhesion molecule 1 |
increases expression |
ISO |
Vincristine results in increased expression of CEACAM1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
|
|
G |
Cebpb |
CCAAT/enhancer binding protein beta |
increases expression |
ISO |
Vincristine results in increased expression of CEBPB mRNA |
CTD |
PMID:16001973 |
|
NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
|
|
G |
Celf1 |
CUGBP, Elav-like family member 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of CELF1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:79,768,900...79,844,548
Ensembl chr 3:79,823,945...79,842,082
|
|
G |
Cenpc |
centromere protein C |
decreases expression |
ISO |
Vincristine results in decreased expression of CENPC1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:23,611,909...23,670,314
Ensembl chr14:23,611,735...23,670,475
|
|
G |
Cenpf |
centromere protein F |
decreases expression |
ISO |
Vincristine results in decreased expression of CENPF mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:108,132,499...108,178,609
Ensembl chr13:108,132,499...108,178,609
|
|
G |
Cenpi |
centromere protein I |
decreases expression |
ISO |
Vincristine results in decreased expression of CENPI mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:105,147,045...105,198,798
Ensembl chr X:105,147,153...105,198,797
|
|
G |
Cenpu |
centromere protein U |
decreases expression |
ISO |
Vincristine results in decreased expression of CENPU mRNA |
CTD |
PMID:23649840 |
|
NCBI chr16:48,898,032...48,921,248
Ensembl chr16:48,897,982...48,921,242
|
|
G |
Cep135 |
centrosomal protein 135 |
increases expression |
ISO |
Vincristine results in increased expression of CEP135 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:34,052,168...34,115,763
Ensembl chr14:34,051,003...34,115,273
|
|
G |
Ces5a |
carboxylesterase 5A |
increases expression |
ISO |
Vincristine results in increased expression of CES5A mRNA |
CTD |
PMID:23649840 |
|
NCBI chr19:12,097,529...12,136,579
Ensembl chr19:12,097,632...12,136,240
|
|
G |
Cflar |
CASP8 and FADD-like apoptosis regulator |
increases expression |
ISO |
Vincristine results in increased expression of CFLAR mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
|
|
G |
Chd1l |
chromodomain helicase DNA binding protein 1-like |
increases expression |
ISO |
Vincristine results in increased expression of CHD1L mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:199,714,044...199,792,270
Ensembl chr 2:199,716,713...199,771,896
|
|
G |
Chek2 |
checkpoint kinase 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of CHEK2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
|
|
G |
Chm |
CHM Rab escort protein |
increases expression |
ISO |
Vincristine results in increased expression of CHM mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:84,666,900...84,821,775
Ensembl chr X:84,666,900...84,821,775
|
|
G |
Chml |
CHM like Rab escort protein |
decreases expression |
ISO |
Vincristine results in decreased expression of CHML mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:93,740,759...93,742,624
|
|
G |
Chtf18 |
chromosome transmission fidelity factor 18 |
decreases expression |
ISO |
Vincristine results in decreased expression of CHTF18 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:15,090,762...15,098,825
Ensembl chr10:15,090,316...15,098,791
|
|
G |
Ciapin1 |
cytokine induced apoptosis inhibitor 1 |
decreases response to substance |
ISO |
CIAPIN1 protein results in decreased susceptibility to Vincristine |
CTD |
PMID:18389626 |
|
NCBI chr19:10,596,923...10,612,414
Ensembl chr19:10,596,960...10,610,049
|
|
G |
Cirbp |
cold inducible RNA binding protein |
decreases expression |
ISO |
Vincristine results in decreased expression of CIRBP mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:12,400,066...12,405,054
Ensembl chr 7:12,401,207...12,405,022
|
|
G |
Clasp2 |
cytoplasmic linker associated protein 2 |
increases expression |
ISO |
Vincristine results in increased expression of CLASP2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:122,003,719...122,185,495
Ensembl chr 8:122,003,916...122,185,495
|
|
G |
Clec2d |
C-type lectin domain family 2, member D |
decreases expression |
ISO |
Vincristine results in decreased expression of CLEC2D mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:162,278,252...162,302,881
Ensembl chr 4:162,292,305...162,302,156
|
|
G |
Clic2 |
chloride intracellular channel 2 |
increases expression |
ISO |
Vincristine results in increased expression of CLIC2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr20:295,338...310,363
Ensembl chr20:295,250...310,380
|
|
G |
Clspn |
claspin |
decreases expression |
ISO |
Vincristine results in decreased expression of CLSPN mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:144,577,670...144,617,507
Ensembl chr 5:144,581,427...144,616,335
|
|
G |
Cnksr2 |
connector enhancer of kinase suppressor of Ras 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of CNKSR2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:39,711,001...39,953,860
Ensembl chr X:39,711,201...39,951,847
|
|
G |
Cnot3 |
CCR4-NOT transcription complex, subunit 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of CNOT3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:64,130,823...64,147,066
Ensembl chr 1:64,130,908...64,147,251
|
|
G |
Cnot6l |
CCR4-NOT transcription complex, subunit 6-like |
decreases expression |
ISO |
Vincristine results in decreased expression of CNOT6L mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:15,059,101...15,148,255
Ensembl chr14:15,059,387...15,146,586
|
|
G |
Cntln |
centlein |
decreases expression |
ISO |
Vincristine results in decreased expression of CNTLN mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:103,251,986...103,367,088
Ensembl chr 5:103,251,986...103,366,264
|
|
G |
Col15a1 |
collagen type XV alpha 1 chain |
decreases response to substance |
ISO |
COL15A1 mRNA results in decreased susceptibility to Vincristine |
CTD |
PMID:25199881 |
|
NCBI chr 5:62,840,360...62,950,240
|
|
G |
Col1a2 |
collagen type I alpha 2 chain |
increases response to substance |
ISO |
COL1A2 mRNA results in increased susceptibility to Vincristine |
CTD |
PMID:25199881 |
|
NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
|
|
G |
Col3a1 |
collagen type III alpha 1 chain |
decreases response to substance |
ISO |
COL3A1 mRNA results in decreased susceptibility to Vincristine |
CTD |
PMID:25199881 |
|
NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
|
|
G |
Col5a2 |
collagen type V alpha 2 chain |
decreases response to substance |
ISO |
COL5A2 mRNA results in decreased susceptibility to Vincristine |
CTD |
PMID:25199881 |
|
NCBI chr 9:52,091,088...52,238,735
Ensembl chr 9:52,092,511...52,238,564
|
|
G |
Comtd1 |
catechol-O-methyltransferase domain containing 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of COMTD1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:2,631,529...2,634,640
Ensembl chr15:2,631,529...2,634,640
|
|
G |
Cp |
ceruloplasmin |
increases expression |
EXP |
Vincristine results in increased expression of CP mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
|
|
G |
Cpeb2 |
cytoplasmic polyadenylation element binding protein 2 |
increases expression |
ISO |
Vincristine results in increased expression of CPEB2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:72,327,929...72,382,519
Ensembl chr14:72,331,705...72,380,330
|
|
G |
Cpne3 |
copine 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of CPNE3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:33,525,307...33,574,610
Ensembl chr 5:33,528,154...33,574,596
|
|
G |
Cpsf6 |
cleavage and polyadenylation specific factor 6 |
decreases expression |
ISO |
Vincristine results in decreased expression of CPSF6 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:60,385,688...60,417,661
Ensembl chr 7:60,385,688...60,416,925
|
|
G |
Crebbp |
CREB binding protein |
increases expression |
ISO |
Vincristine results in increased expression of CREBBP mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:11,590,994...11,721,039
Ensembl chr10:11,595,044...11,721,039
|
|
G |
Crebrf |
CREB3 regulatory factor |
increases expression |
ISO |
Vincristine results in increased expression of CREBRF mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:16,693,846...16,753,162
Ensembl chr10:16,694,792...16,752,205
|
|
G |
Crebzf |
CREB/ATF bZIP transcription factor |
decreases expression |
ISO |
Vincristine results in decreased expression of CREBZF mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:156,290,215...156,296,891
Ensembl chr 1:156,294,519...156,296,161
|
|
G |
Crtap |
cartilage associated protein |
decreases expression |
ISO |
Vincristine results in decreased expression of CRTAP mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:122,382,613...122,402,209
|
|
G |
Crtc3 |
CREB regulated transcription coactivator 3 |
increases expression |
ISO |
Vincristine results in increased expression of CRTC3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:142,398,248...142,500,562
Ensembl chr 1:142,393,207...142,500,383
|
|
G |
Csad |
cysteine sulfinic acid decarboxylase |
decreases expression |
ISO |
Vincristine results in decreased expression of CSAD mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:143,781,520...143,810,880
Ensembl chr 7:143,781,702...143,793,970
|
|
G |
Csf2 |
colony stimulating factor 2 |
increases expression |
ISO |
Vincristine results in increased expression of CSF2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
|
|
G |
Csnk1a1 |
casein kinase 1, alpha 1 |
increases expression |
ISO |
Vincristine results in increased expression of CSNK1A1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr18:56,887,722...56,910,610
Ensembl chr18:56,887,354...56,918,345
|
|
G |
Csnk1g1 |
casein kinase 1, gamma 1 |
increases expression |
ISO |
Vincristine results in increased expression of CSNK1G1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:71,533,372...71,688,483
Ensembl chr 8:71,547,468...71,679,666
|
|
G |
Csta |
cystatin A |
increases expression |
ISO |
Vincristine results in increased expression of CSTA mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:67,555,792...67,566,980
Ensembl chr11:67,555,658...67,566,972
|
|
G |
Cstf1 |
cleavage stimulation factor subunit 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of CSTF1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:170,380,413...170,392,162
Ensembl chr 3:170,380,719...170,392,160
|
|
G |
Ctc1 |
CST telomere replication complex component 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of CTC1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:55,596,172...55,616,873
Ensembl chr10:55,596,148...55,616,889
|
|
G |
Cth |
cystathionine gamma-lyase |
increases expression |
ISO |
Vincristine results in increased expression of CTH mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
|
|
G |
Ctnnal1 |
catenin alpha-like 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of CTNNAL1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:73,561,249...73,621,070
Ensembl chr 5:73,561,450...73,621,070
|
|
G |
Ctnnb1 |
catenin beta 1 |
increases expression decreases response to substance |
ISO |
Vincristine results in increased expression of CTNNB1 mRNA CTNNB1 results in decreased susceptibility to Vincristine |
CTD |
PMID:22000491 PMID:23649840 |
|
NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
|
|
G |
Cul4a |
cullin 4A |
increases expression |
ISO |
Vincristine results in increased expression of CUL4A mRNA |
CTD |
PMID:23649840 |
|
NCBI chr16:81,718,784...81,756,653
Ensembl chr16:81,719,028...81,756,654
|
|
G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
increases expression |
ISO |
Vincristine results in increased expression of CXCL10 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
|
|
G |
Cxcl11 |
C-X-C motif chemokine ligand 11 |
increases expression |
ISO |
Vincristine results in increased expression of CXCL11 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:17,195,395...17,198,170
Ensembl chr14:17,195,014...17,198,291
|
|
G |
Cxcl9 |
C-X-C motif chemokine ligand 9 |
increases expression |
ISO |
Vincristine results in increased expression of CXCL9 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
|
|
G |
Cyld |
CYLD lysine 63 deubiquitinase |
increases expression |
ISO |
Vincristine results in increased expression of CYLD mRNA |
CTD |
PMID:23649840 |
|
NCBI chr19:19,264,984...19,323,817
Ensembl chr19:19,265,164...19,315,357
|
|
G |
Cyp2c79 |
cytochrome P450, family 2, subfamily c, polypeptide 79 |
increases response to substance |
ISO |
CYP2C8 gene SNP results in increased susceptibility to Vincristine |
CTD |
PMID:21245421 |
|
NCBI chr 1:147,236,480...147,307,988
|
|
G |
Cyp3a62 |
cytochrome P450, family 3, subfamily a, polypeptide 62 |
increases metabolic processing |
ISO |
CYP3A4 protein results in increased metabolism of Vincristine |
CTD |
PMID:19346885 |
|
NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
|
|
G |
Cyp3a9 |
cytochrome P450, family 3, subfamily a, polypeptide 9 |
multiple interactions increases metabolic processing |
ISO |
[CYP3A5 gene polymorphism results in increased activity of CYP3A5 protein] which results in increased metabolism of Vincristine CYP3A5 protein results in increased metabolism of Vincristine |
CTD |
PMID:21225912 |
|
NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
|
|
G |
Cyp4f18 |
cytochrome P450, family 4, subfamily f, polypeptide 18 |
increases expression |
ISO |
Vincristine results in increased expression of CYP4F3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr16:19,501,680...19,528,935
Ensembl chr16:19,410,810...19,528,999
|
|
G |
Cyp4v3 |
cytochrome P450, family 4, subfamily v, polypeptide 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of CYP4V2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr16:50,111,803...50,136,741
Ensembl chr16:50,111,306...50,136,727
|
|
G |
Cysltr1 |
cysteinyl leukotriene receptor 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of CYSLTR1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:77,671,028...77,700,491
Ensembl chr X:77,674,150...77,700,269
|
|
G |
Daam1 |
dishevelled associated activator of morphogenesis 1 |
increases expression |
ISO |
Vincristine results in increased expression of DAAM1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:94,606,675...94,739,026
Ensembl chr 6:94,636,222...94,739,026
|
|
G |
Dcaf8 |
DDB1 and CUL4 associated factor 8 |
increases expression |
ISO |
Vincristine results in increased expression of DCAF8 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:90,532,153...90,587,542
Ensembl chr13:90,532,326...90,591,796
|
|
G |
Dcn |
decorin |
decreases response to substance |
ISO |
DCN mRNA results in decreased susceptibility to Vincristine |
CTD |
PMID:25199881 |
|
NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
|
|
G |
Dcun1d1 |
defective in cullin neddylation 1 domain containing 1 |
increases expression |
ISO |
Vincristine results in increased expression of DCUN1D1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:122,476,173...122,527,153
Ensembl chr 2:122,476,173...122,646,445
|
|
G |
Dcun1d4 |
defective in cullin neddylation 1 domain containing 4 |
decreases expression |
ISO |
Vincristine results in decreased expression of DCUN1D4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:37,210,721...37,294,517
Ensembl chr14:37,210,721...37,294,472
|
|
G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression |
ISO |
Vincristine results in increased expression of DDIT3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
|
|
G |
Ddx50 |
DExD-box helicase 50 |
increases expression |
ISO |
Vincristine results in increased expression of DDX50 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr20:32,239,736...32,269,522
Ensembl chr20:32,239,748...32,269,145
|
|
G |
Ddx52 |
DExD-box helicase 52 |
increases expression |
ISO |
Vincristine results in increased expression of DDX52 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:71,253,667...71,276,397
Ensembl chr10:71,253,598...71,277,277
|
|
G |
Dennd5a |
DENN domain containing 5A |
increases expression |
ISO |
Vincristine results in increased expression of DENND5A mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:174,524,047...174,588,553
Ensembl chr 1:174,524,047...174,588,529
|
|
G |
Dgcr8 |
DGCR8 microprocessor complex subunit |
decreases expression |
ISO |
Vincristine results in decreased expression of DGCR8 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:86,852,682...86,885,233
Ensembl chr11:86,852,711...86,885,224
|
|
G |
Dhfr |
dihydrofolate reductase |
decreases expression |
ISO |
Vincristine results in decreased expression of DHFR mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453
|
|
G |
Dhrs11 |
dehydrogenase/reductase 11 |
decreases expression |
ISO |
Vincristine results in decreased expression of DHRS11 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:72,144,042...72,153,496
Ensembl chr10:72,144,042...72,153,375
|
|
G |
Dhrs2 |
dehydrogenase/reductase 2 |
increases expression |
ISO |
Vincristine results in increased expression of DHRS2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:33,876,701...33,891,559
Ensembl chr15:33,885,106...33,891,539
|
|
G |
Dhrs7 |
dehydrogenase/reductase 7 |
increases expression |
ISO |
Vincristine results in increased expression of DHRS7 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:95,522,577...95,541,393
Ensembl chr 6:95,522,577...95,541,393
|
|
G |
Diablo |
diablo, IAP-binding mitochondrial protein |
decreases expression |
ISO |
Vincristine results in decreased expression of DIABLO mRNA |
CTD |
PMID:23649840 |
|
NCBI chr12:38,490,230...38,503,344
Ensembl chr12:38,490,230...38,503,330
|
|
G |
Dido1 |
death inducer-obliterator 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of DIDO1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:176,162,886...176,216,868
Ensembl chr 3:176,162,886...176,197,753
|
|
G |
Dip2a |
disco-interacting protein 2 homolog A |
increases expression |
ISO |
Vincristine results in increased expression of DIP2A mRNA |
CTD |
PMID:23649840 |
|
NCBI chr20:13,044,056...13,127,971
Ensembl chr20:13,044,104...13,127,487
|
|
G |
Dmd |
dystrophin |
increases expression |
ISO |
Vincristine results in increased expression of DMD mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:51,149,358...53,519,271
Ensembl chr X:51,286,737...53,519,259
|
|
G |
Dna2 |
DNA replication helicase/nuclease 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of DNA2 mRNA |
CTD |
PMID:23649840 |
|
|
|
G |
Dnajb1 |
DnaJ heat shock protein family (Hsp40) member B1 |
decreases expression |
ISO |
Vincristine results in decreased expression of DNAJB1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919
|
|
G |
Dnajc7 |
DnaJ heat shock protein family (Hsp40) member C7 |
increases expression |
ISO |
Vincristine results in increased expression of DNAJC7 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:88,498,271...88,533,730
Ensembl chr10:88,498,238...88,533,829
|
|
G |
Dnase1l3 |
deoxyribonuclease 1-like 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of DNASE1L3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:18,710,492...18,736,476
Ensembl chr15:18,710,492...18,736,473
|
|
G |
Dnmbp |
dynamin binding protein |
decreases expression |
ISO |
Vincristine results in decreased expression of DNMBP mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:263,625,503...263,718,784
Ensembl chr 1:263,625,501...263,718,745
|
|
G |
Dock4 |
dedicator of cytokinesis 4 |
increases expression |
ISO |
Vincristine results in increased expression of DOCK4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:60,374,839...60,782,648
Ensembl chr 6:60,566,196...60,782,556
|
|
G |
Dock8 |
dedicator of cytokinesis 8 |
decreases expression |
ISO |
Vincristine results in decreased expression of DOCK8 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:242,934,685...243,153,472
Ensembl chr 1:242,959,488...243,153,465
|
|
G |
Dok4 |
docking protein 4 |
increases expression |
ISO |
Vincristine results in increased expression of DOK4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr19:10,563,423...10,574,094
Ensembl chr19:10,563,423...10,574,093
|
|
G |
Donson |
DNA replication fork stabilization factor DONSON |
decreases expression |
ISO |
Vincristine results in decreased expression of DONSON mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:31,834,608...31,847,751
Ensembl chr11:31,837,839...31,847,490
|
|
G |
Dpp4 |
dipeptidylpeptidase 4 |
decreases expression |
ISO |
Vincristine results in decreased expression of DPP4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:48,291,055...48,372,672
Ensembl chr 3:48,291,055...48,372,672
|
|
G |
Dpyd |
dihydropyrimidine dehydrogenase |
increases response to substance |
ISO |
DPYD gene SNP results in increased susceptibility to Vincristine |
CTD |
PMID:20864405 |
|
NCBI chr 2:221,823,692...222,694,627
Ensembl chr 2:221,823,687...222,694,627
|
|
G |
Dram1 |
DNA-damage regulated autophagy modulator 1 |
increases expression |
ISO |
Vincristine results in increased expression of DRAM1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:28,898,647...28,932,641
Ensembl chr 7:28,898,649...28,932,641
|
|
G |
Dtl |
denticleless E3 ubiquitin protein ligase homolog |
decreases expression |
ISO |
Vincristine results in decreased expression of DTL mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:110,219,276...110,257,345
Ensembl chr13:110,220,283...110,257,367
|
|
G |
Dusp1 |
dual specificity phosphatase 1 |
increases expression |
ISO |
Vincristine results in increased expression of DUSP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
|
|
G |
Dusp10 |
dual specificity phosphatase 10 |
increases expression |
ISO |
Vincristine results in increased expression of DUSP10 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:104,284,660...104,321,455
Ensembl chr13:104,284,660...104,321,455
|
|
G |
Dusp16 |
dual specificity phosphatase 16 |
increases expression |
ISO |
Vincristine results in increased expression of DUSP16 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:168,470,141...168,551,346
Ensembl chr 4:168,472,412...168,517,177
|
|
G |
Dusp2 |
dual specificity phosphatase 2 |
increases expression |
ISO |
Vincristine results in increased expression of DUSP2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:119,776,925...119,779,110
Ensembl chr 3:119,776,925...119,779,099
|
|
G |
Dusp4 |
dual specificity phosphatase 4 |
increases expression |
ISO |
Vincristine results in increased expression of DUSP4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr16:61,080,767...61,090,973
Ensembl chr16:61,078,175...61,091,169
|
|
G |
Dynlt2 |
dynein light chain Tctex-type 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of DYNLT2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:56,970,673...56,982,657
Ensembl chr 1:56,970,654...56,982,642
|
|
G |
E2f8 |
E2F transcription factor 8 |
decreases expression |
ISO |
Vincristine results in decreased expression of E2F8 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:104,185,436...104,203,683
Ensembl chr 1:104,187,100...104,202,591
|
|
G |
Ebf1 |
EBF transcription factor 1 |
increases expression |
ISO |
Vincristine results in increased expression of EBF1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:23,654,849...24,051,627
Ensembl chr10:23,661,013...24,050,209
|
|
G |
Ednrb |
endothelin receptor type B |
increases expression |
EXP |
Vincristine results in increased expression of EDNRB mRNA |
CTD |
PMID:20624997 |
|
NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
|
|
G |
Efna4 |
ephrin A4 |
decreases expression |
ISO |
Vincristine results in decreased expression of EFNA4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:188,655,920...188,660,179
Ensembl chr 2:188,655,912...188,660,179
|
|
G |
Egfl6 |
EGF-like-domain, multiple 6 |
decreases response to substance |
ISO |
EGFL6 mRNA results in decreased susceptibility to Vincristine |
CTD |
PMID:25199881 |
|
NCBI chr X:29,430,789...29,488,737
Ensembl chr X:29,430,831...29,488,739
|
|
G |
Egr1 |
early growth response 1 |
increases expression |
ISO |
Vincristine results in increased expression of EGR1 mRNA |
CTD |
PMID:12706485 PMID:23649840 |
|
NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
|
|
G |
Egr3 |
early growth response 3 |
increases expression |
ISO |
Vincristine results in increased expression of EGR3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:51,756,683...51,762,080
Ensembl chr15:51,756,736...51,760,722
|
|
G |
Ehbp1l1 |
EH domain binding protein 1-like 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of EHBP1L1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:221,061,878...221,084,423
Ensembl chr 1:221,062,147...221,084,129
|
|
G |
Eif1 |
eukaryotic translation initiation factor 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of EIF1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:88,227,455...88,229,546
Ensembl chr10:88,227,360...88,229,765
|
|
G |
Eif1ad |
eukaryotic translation initiation factor 1A domain containing |
decreases expression |
ISO |
Vincristine results in decreased expression of EIF1AD mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:220,746,387...220,751,687
Ensembl chr 1:220,746,387...220,751,684
|
|
G |
Eif3b |
eukaryotic translation initiation factor 3, subunit B |
decreases expression |
ISO |
Vincristine results in decreased expression of EIF3B mRNA |
CTD |
PMID:23649840 |
|
NCBI chr12:16,285,730...16,310,190
Ensembl chr12:16,285,733...16,310,190
|
|
G |
Eif3m |
eukaryotic translation initiation factor 3, subunit M |
increases expression |
ISO |
Vincristine results in increased expression of EIF3M mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:94,990,086...95,007,690
Ensembl chr 3:94,990,068...95,007,712
|
|
G |
Eif4a1 |
eukaryotic translation initiation factor 4A1 |
increases expression |
ISO |
Vincristine results in increased expression of EIF4A1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:56,271,257...56,276,764
Ensembl chr10:56,271,257...56,276,764
|
|
G |
Eif4a2 |
eukaryotic translation initiation factor 4A2 |
decreases expression |
ISO |
Vincristine results in decreased expression of EIF4A2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:81,373,047...81,379,680
Ensembl chr11:81,373,048...81,379,871
|
|
G |
Elf3 |
E74 like ETS transcription factor 3 |
increases expression |
ISO |
Vincristine results in increased expression of ELF3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:52,083,873...52,088,798
Ensembl chr13:52,083,859...52,088,780
|
|
G |
Elk3 |
ETS transcription factor ELK3 |
increases expression |
ISO |
Vincristine results in increased expression of ELK3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:34,086,213...34,149,601
Ensembl chr 7:34,086,220...34,121,694
|
|
G |
Eme2 |
essential meiotic structure-specific endonuclease subunit 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of EME2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:14,253,552...14,257,017
Ensembl chr10:14,254,252...14,256,930
|
|
G |
Eml6 |
EMAP like 6 |
decreases expression |
ISO |
Vincristine results in decreased expression of EML6 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:114,174,282...114,484,663
Ensembl chr14:114,176,051...114,484,127
|
|
G |
Enox1 |
ecto-NOX disulfide-thiol exchanger 1 |
increases expression |
ISO |
Vincristine results in increased expression of ENOX1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:59,331,134...59,884,512
Ensembl chr15:59,678,165...59,884,511
|
|
G |
Enpp2 |
ectonucleotide pyrophosphatase/phosphodiesterase 2 |
increases expression |
ISO |
Vincristine results in increased expression of ENPP2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
|
|
G |
Ensa |
endosulfine alpha |
decreases expression |
ISO |
Vincristine results in decreased expression of ENSA mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:197,752,544...197,759,882
Ensembl chr 2:197,752,544...197,759,882
|
|
G |
Entpd2 |
ectonucleoside triphosphate diphosphohydrolase 2 |
increases expression |
ISO |
Vincristine results in increased expression of ENTPD2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:2,617,795...2,623,818
Ensembl chr 3:2,617,805...2,623,445
|
|
G |
Eomes |
eomesodermin |
decreases expression |
ISO |
Vincristine results in decreased expression of EOMES mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:127,144,367...127,152,618
Ensembl chr 8:127,144,903...127,151,493
|
|
G |
Epg5 |
ectopic P-granules autophagy protein 5 homolog |
increases expression |
ISO |
Vincristine results in increased expression of EPG5 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr18:74,299,965...74,397,115
Ensembl chr18:74,299,931...74,395,547
|
|
G |
Ephb1 |
Eph receptor B1 |
decreases expression |
ISO |
Vincristine results in decreased expression of EPHB1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:110,376,954...110,813,193
Ensembl chr 8:110,376,954...110,813,000
|
|
G |
Ephx1 |
epoxide hydrolase 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of EPHX1 mRNA |
CTD |
PMID:21382384 |
|
NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
|
|
G |
Epm2aip1 |
EPM2A interacting protein 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of EPM2AIP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:119,524,039...119,531,387
Ensembl chr 8:119,524,039...119,531,387
|
|
G |
Epor |
erythropoietin receptor |
decreases expression |
ISO |
Vincristine results in decreased expression of EPOR mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:22,969,737...22,974,468
Ensembl chr 8:22,969,745...22,974,321
|
|
G |
Eprs |
glutamyl-prolyl-tRNA synthetase |
increases expression |
EXP |
Vincristine results in increased expression of EPRS mRNA |
CTD |
PMID:20624997 |
|
NCBI chr13:103,300,911...103,371,651
Ensembl chr13:103,300,932...103,371,577
|
|
G |
Epsti1 |
epithelial stromal interaction 1 |
increases expression |
ISO |
Vincristine results in increased expression of EPSTI1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:60,084,966...60,190,360
Ensembl chr15:60,084,918...60,190,363
|
|
G |
Erich3 |
glutamate-rich 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of ERICH3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:260,947,970...261,049,973
Ensembl chr 2:260,997,497...261,032,821
|
|
G |
Esco2 |
establishment of sister chromatid cohesion N-acetyltransferase 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of ESCO2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:42,500,929...42,519,019
Ensembl chr15:42,500,929...42,518,855
|
|
G |
Esd |
esterase D |
decreases expression |
ISO |
Vincristine results in decreased expression of ESD mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:56,756,848...56,776,348
Ensembl chr15:56,756,661...56,776,348
|
|
G |
Esm1 |
endothelial cell-specific molecule 1 |
decreases expression |
EXP |
Vincristine results in decreased expression of ESM1 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 2:45,104,392...45,113,130
Ensembl chr 2:45,104,305...45,113,131
|
|
G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
Vincristine binds to and results in decreased activity of ESR1 protein |
CTD |
PMID:25752796 |
|
NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
|
|
G |
Evc |
EvC ciliary complex subunit 1 |
increases expression |
ISO |
Vincristine results in increased expression of EVC mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:78,213,601...78,253,266
Ensembl chr14:78,213,635...78,253,266
|
|
G |
Exo1 |
exonuclease 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of EXO1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:93,936,989...93,962,749
Ensembl chr13:93,939,022...93,960,342
|
|
G |
Exog |
exo/endonuclease G |
decreases expression |
ISO |
Vincristine results in decreased expression of EXOG mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:128,133,398...128,153,110
Ensembl chr 8:128,133,431...128,153,110
|
|
G |
Ext1 |
exostosin glycosyltransferase 1 |
increases expression |
ISO |
Vincristine results in increased expression of EXT1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:92,605,008...92,881,392
Ensembl chr 7:92,605,728...92,882,068
|
|
G |
F2 |
coagulation factor II |
affects expression |
ISO |
Vincristine affects the expression of F2 protein |
CTD |
PMID:12542493 |
|
NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
|
|
G |
F3 |
coagulation factor III, tissue factor |
increases expression |
ISO EXP |
Vincristine results in increased expression of F3 mRNA; Vincristine results in increased expression of F3 protein |
CTD |
PMID:12542493 PMID:20624997 |
|
NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
|
|
G |
Fam13b |
family with sequence similarity 13, member B |
increases expression |
ISO |
Vincristine results in increased expression of FAM13B mRNA |
CTD |
PMID:23649840 |
|
NCBI chr18:27,223,345...27,304,462
Ensembl chr18:27,223,345...27,289,876
|
|
G |
Fam13c |
family with sequence similarity 13, member C |
increases expression |
ISO |
Vincristine results in increased expression of FAM13C mRNA |
CTD |
PMID:23649840 |
|
NCBI chr20:19,358,869...19,470,212
Ensembl chr20:19,360,230...19,479,325
|
|
G |
Fam171b |
family with sequence similarity 171, member B |
decreases expression |
ISO |
Vincristine results in decreased expression of FAM171B mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:71,210,048...71,265,419
Ensembl chr 3:71,210,301...71,262,615
|
|
G |
Fam174a |
family with sequence similarity 174, member A |
increases expression |
ISO |
Vincristine results in increased expression of FAM174A mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:102,862,761...102,881,046
Ensembl chr 9:102,862,890...102,881,038
|
|
G |
Fam71f1 |
family with sequence similarity 71, member F1 |
increases expression |
ISO |
Vincristine results in increased expression of FAM71F1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:56,591,719...56,615,157
Ensembl chr 4:56,591,715...56,615,158
|
|
G |
Fam76b |
family with sequence similarity 76, member B |
decreases expression |
ISO |
Vincristine results in decreased expression of FAM76B mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:12,355,767...12,378,040
Ensembl chr 8:12,355,767...12,374,689
|
|
G |
Fam81a |
family with sequence similarity 81, member A |
decreases expression |
ISO |
Vincristine results in decreased expression of FAM81A mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:76,521,662...76,579,387
Ensembl chr 8:76,521,657...76,579,387
|
|
G |
Fam83d |
family with sequence similarity 83, member D |
decreases expression |
ISO |
Vincristine results in decreased expression of FAM83D mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:155,269,344...155,288,612
Ensembl chr 3:155,269,347...155,288,533
|
|
G |
Fancf |
FA complementation group F |
decreases expression |
ISO |
Vincristine results in decreased expression of FANCF mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:107,229,516...107,232,321
Ensembl chr 1:107,231,292...107,232,305
|
|
G |
Fancg |
FA complementation group G |
decreases expression |
ISO |
Vincristine results in decreased expression of FANCG mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:58,448,060...58,456,416
Ensembl chr 5:58,448,822...58,455,819
|
|
G |
Fas |
Fas cell surface death receptor |
increases expression |
ISO |
Vincristine results in increased expression of FAS mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
|
|
G |
Faslg |
Fas ligand |
increases expression |
ISO |
Vincristine results in increased expression of FASLG protein |
CTD |
PMID:11716366 |
|
NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
|
|
G |
Fastkd2 |
FAST kinase domains 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of FASTKD2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:70,448,386...70,471,420
Ensembl chr 9:70,450,444...70,470,550
|
|
G |
Fbxl20 |
F-box and leucine-rich repeat protein 20 |
decreases expression |
ISO |
Vincristine results in decreased expression of FBXL20 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:86,036,745...86,099,699
Ensembl chr10:86,043,235...86,098,694
|
|
G |
Fbxl4 |
F-box and leucine-rich repeat protein 4 |
decreases expression |
ISO |
Vincristine results in decreased expression of FBXL4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:36,555,061...36,628,920
Ensembl chr 5:36,555,109...36,629,689
|
|
G |
Fbxo33 |
F-box protein 33 |
decreases expression |
ISO |
Vincristine results in decreased expression of FBXO33 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:80,302,291...80,334,536
Ensembl chr 6:80,302,303...80,334,522
|
|
G |
Fbxo5 |
F-box protein 5 |
decreases expression |
ISO |
Vincristine results in decreased expression of FBXO5 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:42,461,277...42,467,646
Ensembl chr 1:42,461,291...42,467,586
|
|
G |
Fbxo9 |
f-box protein 9 |
decreases expression |
ISO |
Vincristine results in decreased expression of FBXO9 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:85,388,331...85,413,896
Ensembl chr 8:85,388,333...85,413,484
|
|
G |
Fcgr2b |
Fc fragment of IgG receptor IIb |
increases expression |
EXP |
Vincristine results in increased expression of FCGR2B mRNA |
CTD |
PMID:20624997 |
|
NCBI chr13:89,329,298...89,343,916
Ensembl chr13:89,327,794...89,433,815
|
|
G |
Fdft1 |
farnesyl diphosphate farnesyl transferase 1 |
increases expression |
ISO |
Vincristine results in increased expression of FDFT1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
|
|
G |
Fermt2 |
FERM domain containing kindlin 2 |
increases expression |
ISO |
Vincristine results in increased expression of FERMT2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:19,807,806...19,876,557
Ensembl chr15:19,807,808...19,876,408
|
|
G |
Ffar2 |
free fatty acid receptor 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of FFAR2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:89,268,197...89,271,942
Ensembl chr 1:89,268,938...89,269,930
|
|
G |
Fgr |
FGR proto-oncogene, Src family tyrosine kinase |
decreases expression |
ISO |
Vincristine results in decreased expression of FGR mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:151,172,189...151,199,746
Ensembl chr 5:151,172,206...151,199,745
|
|
G |
Flot2 |
flotillin 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of FLOT2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:65,304,901...65,329,332
Ensembl chr10:65,304,902...65,329,312
|
|
G |
Flt1 |
Fms related receptor tyrosine kinase 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of FLT1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
|
|
G |
Fmnl3 |
formin-like 3 |
increases expression |
ISO |
Vincristine results in increased expression of FMNL3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:140,981,801...141,033,318
Ensembl chr 7:140,983,342...141,001,993
|
|
G |
Fnbp1 |
formin binding protein 1 |
increases expression |
ISO |
Vincristine results in increased expression of FNBP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:9,865,657...9,936,333
Ensembl chr 3:9,861,237...9,936,405
|
|
G |
Fnbp4 |
formin binding protein 4 |
increases expression |
ISO |
Vincristine results in increased expression of FNBP4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:79,570,610...79,610,122
Ensembl chr 3:79,570,625...79,610,454
|
|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression |
EXP |
Vincristine results in increased expression of FOS protein |
CTD |
PMID:18930597 |
|
NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
|
|
G |
Fosl2 |
FOS like 2, AP-1 transcription factor subunit |
increases expression |
ISO |
Vincristine results in increased expression of FOSL2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:25,598,936...25,616,995
Ensembl chr 6:25,598,936...25,616,995
|
|
G |
Foxk2 |
forkhead box K2 |
decreases expression |
ISO |
Vincristine results in decreased expression of FOXK2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:110,468,905...110,518,854
Ensembl chr10:110,469,290...110,518,848
|
|
G |
Foxp1 |
forkhead box P1 |
increases expression |
ISO |
Vincristine results in increased expression of FOXP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:131,362,178...131,963,466
Ensembl chr 4:131,366,744...131,694,755
|
|
G |
Fry |
FRY microtubule binding protein |
decreases expression |
ISO |
Vincristine results in decreased expression of FRY mRNA |
CTD |
PMID:23649840 |
|
NCBI chr12:5,573,729...5,822,874
Ensembl chr12:5,573,729...5,822,874
|
|
G |
Fscn1 |
fascin actin-bundling protein 1 |
increases expression |
ISO |
Vincristine results in increased expression of FSCN1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr12:13,655,459...13,668,595
Ensembl chr12:13,656,554...13,668,515
|
|
G |
Fsd1l |
fibronectin type III and SPRY domain containing 1-like |
increases expression |
ISO |
Vincristine results in increased expression of FSD1L mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:70,441,075...70,517,131
Ensembl chr 5:70,441,123...70,511,659
|
|
G |
Fubp1 |
far upstream element binding protein 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of FUBP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:257,425,676...257,452,745
Ensembl chr 2:257,425,679...257,449,568
|
|
G |
Fut11 |
fucosyltransferase 11 |
decreases expression |
ISO |
Vincristine results in decreased expression of FUT11 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:4,031,504...4,035,064
Ensembl chr15:4,031,504...4,035,064
|
|
G |
G3bp1 |
G3BP stress granule assembly factor 1 |
increases expression |
ISO |
Vincristine results in increased expression of G3BP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:40,812,858...40,846,252
Ensembl chr10:40,812,858...40,846,252
|
|
G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
increases expression |
EXP ISO |
Vincristine results in increased expression of GADD45A mRNA |
CTD |
PMID:20624997 PMID:23649840 |
|
NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
|
|
G |
Gadd45b |
growth arrest and DNA-damage-inducible, beta |
increases expression |
EXP |
Vincristine results in increased expression of GADD45B mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322
|
|
G |
Gadd45g |
growth arrest and DNA-damage-inducible, gamma |
increases expression |
EXP |
Vincristine results in increased expression of GADD45G mRNA |
CTD |
PMID:20624997 |
|
NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243
|
|
G |
Gart |
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase |
decreases expression |
ISO |
Vincristine results in decreased expression of GART mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:31,780,477...31,805,728
Ensembl chr11:31,780,487...31,805,728
|
|
G |
Gas7 |
growth arrest specific 7 |
decreases expression |
EXP |
Vincristine results in decreased expression of GAS7 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr10:54,010,723...54,240,805
Ensembl chr10:54,126,486...54,236,476
|
|
G |
Gbp1 |
guanylate binding protein 1 |
increases expression |
ISO |
Vincristine results in increased expression of GBP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:248,343,334...248,423,402
Ensembl chr 2:248,398,917...248,409,570
|
|
G |
Gbp2 |
guanylate binding protein 2 |
increases expression |
ISO |
Vincristine results in increased expression of GBP2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:248,276,795...248,293,784
Ensembl chr 2:248,276,709...248,293,784
|
|
G |
Gbp6 |
guanylate binding protein family member 6 |
decreases expression |
ISO |
Vincristine results in decreased expression of GBP6 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:5,927,568...5,954,923
Ensembl chr14:5,928,737...5,945,321
|
|
G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions |
ISO |
[GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Vincristine |
CTD |
PMID:10900222 |
|
NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
|
|
G |
Gclm |
glutamate cysteine ligase, modifier subunit |
multiple interactions decreases expression |
ISO |
[GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Vincristine Vincristine results in decreased expression of GCLM mRNA |
CTD |
PMID:10900222 PMID:23649840 |
|
NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
|
|
G |
Gdf15 |
growth differentiation factor 15 |
increases expression |
ISO |
Vincristine results in increased expression of GDF15 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
|
|
G |
Gfi1 |
growth factor independent 1 transcriptional repressor |
decreases expression |
ISO |
Vincristine results in decreased expression of GFI1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:3,058,035...3,073,332
Ensembl chr14:3,058,993...3,068,371
|
|
G |
Gfm1 |
G elongation factor, mitochondrial 1 |
increases expression |
ISO |
Vincristine results in increased expression of GFM1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:164,601,575...164,646,478
Ensembl chr 2:164,601,586...164,646,439
|
|
G |
Gjc1 |
gap junction protein, gamma 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of GJC1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:90,781,408...90,912,440
Ensembl chr10:90,781,402...90,912,287
|
|
G |
Gli1 |
GLI family zinc finger 1 |
increases response to substance |
ISO |
GLI1 gene SNP results in increased susceptibility to Vincristine |
CTD |
PMID:20864405 |
|
NCBI chr 7:70,620,794...70,633,171
Ensembl chr 7:70,620,766...70,630,338
|
|
G |
Glipr1 |
GLI pathogenesis-related 1 |
increases expression |
ISO |
Vincristine results in increased expression of GLIPR1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:54,767,828...54,778,823
Ensembl chr 7:54,767,827...54,778,848
|
|
G |
Gmfb |
glia maturation factor, beta |
increases expression |
ISO |
Vincristine results in increased expression of GMFB mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:23,597,846...23,611,541
Ensembl chr15:23,601,368...23,606,634
|
|
G |
Gmppb |
GDP-mannose pyrophosphorylase B |
decreases expression |
ISO |
Vincristine results in decreased expression of GMPPB mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:116,826,251...116,856,159
Ensembl chr 8:116,826,680...116,856,159
|
|
G |
Gna15 |
G protein subunit alpha 15 |
increases expression |
ISO |
Vincristine results in increased expression of GNA15 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:11,054,249...11,075,152
Ensembl chr 7:11,054,333...11,077,251
|
|
G |
Gng2 |
G protein subunit gamma 2 |
increases expression |
ISO |
Vincristine results in increased expression of GNG2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:4,748,242...4,853,555
Ensembl chr15:4,850,122...4,853,555
|
|
G |
Gon4l |
gon-4 like |
increases expression |
ISO |
Vincristine results in increased expression of GON4L mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:188,139,730...188,212,902
Ensembl chr 2:188,139,730...188,215,723
|
|
G |
Gopc |
golgi associated PDZ and coiled-coil motif containing |
decreases expression |
ISO |
Vincristine results in decreased expression of GOPC mRNA |
CTD |
PMID:23649840 |
|
NCBI chr20:33,471,355...33,521,281
Ensembl chr20:33,471,351...33,521,311
|
|
G |
Gpatch11 |
G patch domain containing 11 |
decreases expression |
ISO |
Vincristine results in decreased expression of GPATCH11 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:1,410,461...1,421,506
Ensembl chr 6:1,410,507...1,423,041
|
|
G |
Gpatch2 |
G patch domain containing 2 |
increases expression |
ISO |
Vincristine results in increased expression of GPATCH2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:105,684,300...105,824,405
Ensembl chr13:105,684,420...105,815,606
|
|
G |
Gpatch2l |
G patch domain containing 2-like |
increases expression |
ISO |
Vincristine results in increased expression of GPATCH2L mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:110,093,767...110,228,943
Ensembl chr 6:110,093,819...110,227,475
|
|
G |
Gpbp1l1 |
GC-rich promoter binding protein 1-like 1 |
increases expression |
ISO |
Vincristine results in increased expression of GPBP1L1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:135,398,926...135,439,772
Ensembl chr 5:135,412,256...135,439,577
|
|
G |
Gpc3 |
glypican 3 |
increases response to substance |
ISO |
GPC3 mRNA results in increased susceptibility to Vincristine |
CTD |
PMID:25199881 |
|
NCBI chr X:139,579,268...139,947,093
Ensembl chr X:139,579,268...139,916,883
|
|
G |
Gpd2 |
glycerol-3-phosphate dehydrogenase 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of GPD2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:43,223,892...43,359,069
Ensembl chr 3:43,255,567...43,359,074
|
|
G |
Gpnmb |
glycoprotein nmb |
increases expression |
ISO |
Vincristine results in increased expression of GPNMB mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:78,694,447...78,715,685
Ensembl chr 4:78,694,447...78,715,683
|
|
G |
Gpr132 |
G protein-coupled receptor 132 |
increases expression |
ISO |
Vincristine results in increased expression of GPR132 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:137,652,213...137,671,658
Ensembl chr 6:137,652,213...137,664,133
|
|
G |
Gpr137b |
G protein-coupled receptor 137B |
increases expression |
ISO |
Vincristine results in increased expression of GPR137B mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:90,670,852...90,709,003
Ensembl chr17:90,670,872...90,746,804
|
|
G |
Gpr180 |
G protein-coupled receptor 180 |
decreases expression |
ISO |
Vincristine results in decreased expression of GPR180 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:103,340,387...103,369,633
Ensembl chr15:103,344,476...103,369,630
|
|
G |
Gpr55 |
G protein-coupled receptor 55 |
increases expression |
ISO |
Vincristine results in increased expression of GPR55 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:92,961,431...93,011,157
Ensembl chr 9:92,962,738...92,963,697
|
|
G |
Gpr63 |
G protein-coupled receptor 63 |
decreases expression |
ISO |
Vincristine results in decreased expression of GPR63 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:39,258,438...39,374,187
Ensembl chr 5:39,329,423...39,370,900
|
|
G |
Gpr84 |
G protein-coupled receptor 84 |
increases expression |
ISO |
Vincristine results in increased expression of GPR84 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:144,934,606...144,937,194
Ensembl chr 7:144,934,610...144,936,803
|
|
G |
Gramd2b |
GRAM domain containing 2B |
increases expression |
ISO |
Vincristine results in increased expression of GRAMD2B mRNA |
CTD |
PMID:23649840 |
|
NCBI chr18:51,492,196...51,591,028
Ensembl chr18:51,492,196...51,591,026
|
|
G |
Grap2 |
GRB2-related adaptor protein 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of GRAP2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:121,791,330...121,864,835
Ensembl chr 7:121,841,855...121,864,679
|
|
G |
Gspt1 |
G1 to S phase transition 1 |
increases expression |
ISO |
Vincristine results in increased expression of GSPT1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:4,313,100...4,347,661
Ensembl chr10:4,312,863...4,446,200
|
|
G |
Gstm1 |
glutathione S-transferase mu 1 |
affects response to substance decreases response to substance multiple interactions |
ISO |
GSTM1 gene polymorphism affects the susceptibility to Vincristine GSTM1 protein results in decreased susceptibility to Vincristine Sulfinpyrazone inhibits the reaction [GSTM1 protein results in decreased susceptibility to Vincristine] |
CTD |
PMID:15044619 PMID:15713801 |
|
NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
|
|
G |
Gstp1 |
glutathione S-transferase pi 1 |
decreases response to substance multiple interactions |
ISO |
GSTP1 protein results in decreased susceptibility to Vincristine GSTP1 protein promotes the reaction [ABCC1 protein results in decreased susceptibility to Vincristine] |
CTD |
PMID:10900222 |
|
NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
|
|
G |
Gtf3c3 |
general transcription factor IIIC subunit 3 |
increases expression |
ISO |
Vincristine results in increased expression of GTF3C3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:60,999,159...61,033,612
Ensembl chr 9:60,969,061...61,033,580
|
|
G |
Gtpbp3 |
GTP binding protein 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of GTPBP3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr16:19,897,135...19,902,226
Ensembl chr16:19,896,986...19,902,245
|
|
G |
H2ax |
H2A.X variant histone |
multiple interactions |
ISO |
[CEP 33779 results in increased susceptibility to Vincristine] which results in increased phosphorylation of H2AX protein; [NVP-BSK805 results in increased susceptibility to Vincristine] which results in increased phosphorylation of H2AX protein |
CTD |
PMID:28669723 |
|
NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
|
|
G |
H2bc12 |
H2B clustered histone 12 |
increases expression |
ISO |
Vincristine results in increased expression of H2BC12 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:44,527,421...44,527,801
Ensembl chr17:44,527,421...44,527,801
|
|
G |
H4c3 |
H4 clustered histone 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of H4C3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:170,144,871...170,145,311
Ensembl chr 4:170,144,951...170,145,262
|
|
G |
Hamp |
hepcidin antimicrobial peptide |
decreases expression |
ISO |
Vincristine results in decreased expression of HAMP mRNA |
CTD |
PMID:25633564 |
|
NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
|
|
G |
Hbb |
hemoglobin subunit beta |
decreases expression |
ISO |
Vincristine results in decreased expression of HBB mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
|
|
G |
Hbb-b1 |
hemoglobin, beta adult major chain |
decreases expression |
ISO |
Vincristine results in decreased expression of HBD mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:168,945,531...168,953,023
Ensembl chr 1:168,945,449...168,965,566
|
|
G |
Hdac1 |
histone deacetylase 1 |
decreases expression |
EXP |
Vincristine results in decreased expression of HDAC1 protein |
CTD |
PMID:27474498 |
|
NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
|
|
G |
Hdac4 |
histone deacetylase 4 |
decreases expression |
EXP |
Vincristine results in decreased expression of HDAC4 protein |
CTD |
PMID:27474498 |
|
NCBI chr 9:99,052,945...99,299,715
Ensembl chr 9:99,057,089...99,299,715
|
|
G |
Hdac9 |
histone deacetylase 9 |
decreases expression |
ISO |
Vincristine results in decreased expression of HDAC9 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:53,487,367...54,358,694
Ensembl chr 6:53,488,883...54,059,119
|
|
G |
Hdhd3 |
haloacid dehalogenase-like hydrolase domain containing 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of HDHD3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:78,358,183...78,361,650
Ensembl chr 5:78,358,203...78,361,647
|
|
G |
Hectd4 |
HECT domain E3 ubiquitin protein ligase 4 |
increases expression |
ISO |
Vincristine results in increased expression of HECTD4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr12:40,712,078...40,860,930
Ensembl chr12:40,713,841...40,822,159
|
|
G |
Hells |
helicase, lymphoid specific |
decreases expression |
ISO |
Vincristine results in decreased expression of HELLS mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:257,901,856...257,953,889
Ensembl chr 1:257,766,691...257,949,183 Ensembl chr 1:257,766,691...257,949,183
|
|
G |
Heph |
hephaestin |
increases expression |
ISO |
Vincristine results in increased expression of HEPH mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:65,377,313...65,658,479
Ensembl chr X:65,563,122...65,658,516
|
|
G |
Hhat |
hedgehog acyltransferase |
increases expression |
ISO |
Vincristine results in increased expression of HHAT mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:111,235,325...111,489,075
Ensembl chr13:111,236,466...111,474,411
|
|
G |
Hic1 |
HIC ZBTB transcriptional repressor 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of HIC1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:62,007,150...62,010,774
Ensembl chr10:62,007,150...62,009,582
|
|
G |
Hilpda |
hypoxia inducible lipid droplet-associated |
decreases expression |
ISO |
Vincristine results in decreased expression of HILPDA mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:56,547,600...56,550,584
Ensembl chr 4:56,549,739...56,549,993
|
|
G |
Hint1 |
histidine triad nucleotide binding protein 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of HINT1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:40,208,236...40,211,981
Ensembl chr10:40,208,223...40,211,975
|
|
G |
Hint3 |
histidine triad nucleotide binding protein 3 |
increases expression |
ISO |
Vincristine results in increased expression of HINT3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:29,413,425...29,423,288
Ensembl chr 1:29,413,365...29,423,347
|
|
G |
Hist1h2bd |
histone cluster 1 H2B family member D |
increases expression |
ISO |
Vincristine results in increased expression of H2BC5 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:44,833,924...44,834,305
Ensembl chr17:44,833,924...44,834,305
|
|
G |
Hist1h2bq |
histone cluster 1 H2B family member Q |
increases expression |
ISO |
Vincristine results in increased expression of H2BC7 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:43,679,925...43,689,311
Ensembl chr17:43,679,925...43,689,311
|
|
G |
Hivep3 |
HIVEP zinc finger 3 |
increases expression |
ISO |
Vincristine results in increased expression of HIVEP3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:138,774,501...139,077,403
Ensembl chr 5:139,007,642...139,077,377
|
|
G |
Hlf |
HLF transcription factor, PAR bZIP family member |
increases expression |
ISO |
Vincristine results in increased expression of HLF mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:77,836,352...77,918,656
Ensembl chr10:77,840,568...77,918,191
|
|
G |
Hmcn1 |
hemicentin 1 |
increases response to substance |
ISO |
HMCN1 mRNA results in increased susceptibility to Vincristine |
CTD |
PMID:25199881 |
|
NCBI chr13:67,799,791...68,360,664
Ensembl chr13:67,799,791...68,360,664
|
|
G |
Hmga2 |
high mobility group AT-hook 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of HMGA2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408
|
|
G |
Hmgb1 |
high mobility group box 1 |
decreases expression increases secretion decreases response to substance |
EXP ISO |
Vincristine results in decreased expression of HMGB1 protein Vincristine results in increased secretion of HMGB1 protein HMGB1 protein results in decreased susceptibility to Vincristine |
CTD |
PMID:27474498 PMID:27807322 |
|
NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
|
|
G |
Hmgn5 |
high mobility group nucleosome binding domain 5 |
decreases expression |
ISO |
Vincristine results in decreased expression of HMGN5 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:80,134,557...80,142,902
Ensembl chr X:80,134,557...80,142,902
|
|
G |
Hmox1 |
heme oxygenase 1 |
decreases expression increases expression |
ISO EXP |
Vincristine results in decreased expression of HMOX1 mRNA Vincristine results in increased expression of HMOX1 mRNA |
CTD |
PMID:20624997 PMID:23649840 |
|
NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
|
|
G |
Hnrnpa2b1 |
heterogeneous nuclear ribonucleoprotein A2/B1 |
decreases expression |
ISO |
Vincristine results in decreased expression of HNRNPA2B1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:81,237,496...81,241,281
Ensembl chr 4:81,237,496...81,241,282
|
|
G |
Hnrnpd |
heterogeneous nuclear ribonucleoprotein D |
decreases expression |
ISO |
Vincristine results in decreased expression of HNRNPD mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:11,256,163...11,274,684
Ensembl chr14:11,256,268...11,274,578
|
|
G |
Hnrnpdl |
heterogeneous nuclear ribonucleoprotein D-like |
decreases expression |
ISO |
Vincristine results in decreased expression of HNRNPDL mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:11,199,114...11,204,670
Ensembl chr14:11,198,896...11,202,669
|
|
G |
Hnrnpr |
heterogeneous nuclear ribonucleoprotein R |
decreases expression |
ISO |
Vincristine results in decreased expression of HNRNPR mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:154,668,194...154,699,967
Ensembl chr 5:154,668,179...154,699,966
|
|
G |
Hnrnpu |
heterogeneous nuclear ribonucleoprotein U |
decreases expression |
ISO |
Vincristine results in decreased expression of HNRNPU mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:96,222,093...96,238,845
Ensembl chr13:96,225,912...96,238,572
|
|
G |
Hook1 |
hook microtubule-tethering protein 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of HOOK1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:114,940,053...115,000,691
Ensembl chr 5:114,940,053...115,000,691
|
|
G |
Hook3 |
hook microtubule-tethering protein 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of HOOK3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr16:70,710,347...70,818,789
|
|
G |
Hoxb7 |
homeo box B7 |
decreases expression |
ISO |
Vincristine results in decreased expression of HOXB7 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:84,135,224...84,138,642
Ensembl chr10:84,135,116...84,138,637
|
|
G |
Hpdl |
4-hydroxyphenylpyruvate dioxygenase-like |
decreases expression |
ISO |
Vincristine results in decreased expression of HPDL mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:135,675,826...135,677,432
Ensembl chr 5:135,675,832...135,677,432
|
|
G |
Hras |
HRas proto-oncogene, GTPase |
increases expression |
ISO |
Vincristine results in increased expression of HRAS mRNA |
CTD |
PMID:16001973 |
|
NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
|
|
G |
Hs2st1 |
heparan sulfate 2-O-sulfotransferase 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of HS2ST1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:250,467,428...250,600,517
Ensembl chr 2:250,467,429...250,600,517
|
|
G |
Hspb11 |
heat shock protein family B (small), member 11 |
decreases expression |
ISO |
Vincristine results in decreased expression of HSPB11 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:126,856,128...126,882,913
Ensembl chr 5:126,856,705...126,882,909
|
|
G |
Hspb2 |
heat shock protein family B (small) member 2 |
decreases response to substance |
ISO |
HSPB2 protein results in decreased susceptibility to Vincristine |
CTD |
PMID:17524270 |
|
NCBI chr 8:55,176,648...55,178,227
Ensembl chr 8:55,176,847...55,177,818
|
|
G |
Hspd1 |
heat shock protein family D (Hsp60) member 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of HSPD1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
|
|
G |
Htr2a |
5-hydroxytryptamine receptor 2A |
multiple interactions increases expression |
EXP |
[alpha-phenyl-1-(2-phenylethyl)-4-piperidinemethanol binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Vincristine Vincristine results in increased expression of HTR2A protein |
CTD |
PMID:18930597 |
|
NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
|
|
G |
Hyls1 |
HYLS1, centriolar and ciliogenesis associated |
decreases expression |
ISO |
Vincristine results in decreased expression of HYLS1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:36,763,470...36,772,199
Ensembl chr 8:36,763,481...36,764,422
|
|
G |
Icam1 |
intercellular adhesion molecule 1 |
increases expression |
ISO EXP |
Vincristine results in increased expression of ICAM1 mRNA |
CTD |
PMID:20624997 PMID:23649840 |
|
NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
|
|
G |
Icam4 |
intercellular adhesion molecule 4, Landsteiner-Wiener blood group |
increases expression |
ISO |
Vincristine results in increased expression of ICAM4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:22,047,697...22,048,793
Ensembl chr 8:22,047,697...22,048,793
|
|
G |
Id2 |
inhibitor of DNA binding 2 |
increases expression |
ISO |
Vincristine results in increased expression of ID2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915
|
|
G |
Id3 |
inhibitor of DNA binding 3, HLH protein |
increases response to substance |
ISO |
ID3 gene SNP results in increased susceptibility to Vincristine |
CTD |
PMID:21245421 |
|
NCBI chr 5:154,489,603...154,491,172
Ensembl chr 5:154,489,590...154,491,223
|
|
G |
Ier3 |
immediate early response 3 |
increases expression |
ISO |
Vincristine results in increased expression of IER3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
|
|
G |
Ifi44 |
interferon-induced protein 44 |
increases expression |
ISO |
Vincristine results in increased expression of IFI44 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:256,897,765...256,915,591
Ensembl chr 2:256,897,772...256,915,569
|
|
G |
Ifi44l |
interferon-induced protein 44-like |
increases expression |
ISO |
Vincristine results in increased expression of IFI44L mRNA |
CTD |
PMID:23649840 |
|
NCBI | |