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Term:Ile(5)-angiotensin II
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Accession:CHEBI:2719 term browser browse the term
Definition:An angiotensin II that acts on the central nervous system (PDB entry: 1N9V).
Synonyms:exact_synonym: L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine
 related_synonym: 5-L-isoleucineangiotensin II;   5-isoleucine-angiotensin II;   Angiotensin;   Angiotonin;   Asp-Arg-Val-Tyr-Ile-His-Pro-Phe;   Formula=C50H71N13O12;   Hypertensin;   InChI=1S/C50H71N13O12/c1-5-28(4)41(47(72)59-36(23-31-25-54-26-56-31)48(73)63-20-10-14-38(63)45(70)60-37(49(74)75)22-29-11-7-6-8-12-29)62-44(69)35(21-30-15-17-32(64)18-16-30)58-46(71)40(27(2)3)61-43(68)34(13-9-19-55-50(52)53)57-42(67)33(51)24-39(65)66/h6-8,11-12,15-18,25-28,33-38,40-41,64H,5,9-10,13-14,19-24,51H2,1-4H3,(H,54,56)(H,57,67)(H,58,71)(H,59,72)(H,60,70)(H,61,68)(H,62,69)(H,65,66)(H,74,75)(H4,52,53,55)/t28-,33-,34-,35-,36-,37-,38-,40-,41-/m0/s1;   InChIKey=CZGUSIXMZVURDU-JZXHSEFVSA-N;   N-(1-(N-(N-(N-(N-(N(2)-L-alpha-aspartyl-L-arginyl)-L-valyl)-L-tyrosyl)-L-isoleucyl)-L-histidyl)-L-prolyl)-L-phenylalanine;   SMILES=CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O;   angiotensin II;   angiotensin II (mouse);   human angiotensin II
 xref: Beilstein:4289487 "Beilstein";   CAS:11128-99-7 "KEGG COMPOUND";   CAS:4474-91-3 "ChemIDplus";   KEGG:C02135
 xref_mesh: MESH:D000804
 xref: PMID:16672146 "Europe PMC";   Reaxys:4289487 "Reaxys"
 cyclic_relationship: is_tautomer_of CHEBI:58506

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Ile(5)-angiotensin II term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agtr2 angiotensin II receptor, type 2 JBrowse link X 119,389,480 119,393,845 RGD:6480464
G Ednrb endothelin receptor type B JBrowse link 15 88,004,775 88,036,354 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19679
    role 19623
      biological role 19621
        molecular messenger 17950
          hormone 17754
            peptide hormone 92
              angiotensin 2
                angiotensin II 2
                  Ile(5)-angiotensin II 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    p-block element atom 19555
                      carbon group element atom 19438
                        carbon atom 19430
                          organic molecular entity 19430
                            organic group 18351
                              organic divalent group 18340
                                organodiyl group 18340
                                  carbonyl group 18225
                                    carbonyl compound 18225
                                      carboxylic acid 17930
                                        carboacyl group 16948
                                          univalent carboacyl group 16948
                                            carbamoyl group 16627
                                              carboxamide 16627
                                                peptide 9297
                                                  peptide hormone 92
                                                    angiotensin 2
                                                      angiotensin II 2
                                                        Ile(5)-angiotensin II 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.