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ONTOLOGY REPORT - ANNOTATIONS


Term:anastrozole
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Accession:CHEBI:2704 term browser browse the term
Definition:A 1,2,4-triazole compound having a 3,5-bis(2-cyano-2-propyl)benzyl group at the 1-position.
Synonyms:exact_synonym: 2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]bis(2-methylpropanenitrile)
 related_synonym: Anastrozol;   Formula=C17H19N5;   InChI=1S/C17H19N5/c1-16(2,9-18)14-5-13(8-22-12-20-11-21-22)6-15(7-14)17(3,4)10-19/h5-7,11-12H,8H2,1-4H3;   InChIKey=YBBLVLTVTVSKRW-UHFFFAOYSA-N;   SMILES=CC(C)(C#N)c1cc(Cn2cncn2)cc(c1)C(C)(C)C#N;   alpha,alpha,alpha',alpha'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
 xref: Beilstein:8005958;   CAS:120511-73-1;   DrugBank:DB01217;   Drug_Central:210;   KEGG:C08159;   KEGG:D00960;   LINCS:LSM-5631
 xref_mesh: MESH:C090450
 xref: Patent:EP296749;   Patent:US4935437;   Wikipedia:Anastrozole


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anastrozole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cycs cytochrome c, somatic JBrowse link 4 80,331,226 80,333,326 RGD:6480464
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:6480464
G Fshb follicle stimulating hormone subunit beta JBrowse link 3 98,088,321 98,092,131 RGD:6480464
G Gja1 gap junction protein, alpha 1 JBrowse link 20 37,876,650 37,889,097 RGD:6480464
G Lhb luteinizing hormone subunit beta JBrowse link 1 101,409,992 101,413,725 RGD:6480464
G Mki67 marker of proliferation Ki-67 JBrowse link 1 207,993,895 208,020,454 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19789
    chemical entity 19788
      group 19698
        pseudohalo group 2879
          cyano group 2879
            nitrile 2879
              anastrozole 8
                1-\{[3,5-bis(1-cyano-1-methylethyl)phenyl]methyl\}-4-[(3S,4R,5R,6R)-6-carboxy-3,4,5-trihydroxyoxan-2-yl]-1,2,4lambda5-triazol-4-ylium 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19789
    subatomic particle 19787
      composite particle 19787
        hadron 19787
          baryon 19787
            nucleon 19787
              atomic nucleus 19787
                atom 19787
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19569
                        carbon atom 19558
                          organic molecular entity 19558
                            organic molecule 19480
                              organic cyclic compound 19239
                                organic heterocyclic compound 18352
                                  heteroarene 15850
                                    monocyclic heteroarene 13207
                                      azole 12356
                                        triazoles 3611
                                          anastrozole 8
                                            1-\{[3,5-bis(1-cyano-1-methylethyl)phenyl]methyl\}-4-[(3S,4R,5R,6R)-6-carboxy-3,4,5-trihydroxyoxan-2-yl]-1,2,4lambda5-triazol-4-ylium 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.