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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:oxolane
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Accession:CHEBI:26911 term browser browse the term
Definition:A cyclic ether that is butane in which one hydrogen from each methyl group is substituted by an oxygen.
Synonyms:related_synonym: 1,4-epoxybutane;   Formula=C4H8O;   InChI=1S/C4H8O/c1-2-4-5-3-1/h1-4H2;   InChIKey=WYURNTSHIVDZCO-UHFFFAOYSA-N;   SMILES=C1CCOC1;   THF;   butane alpha,delta-oxide;   butylene oxide;   furanidine;   tetrahydrofuran;   tetramethylene oxide
 xref: Beilstein:102391;   CAS:109-99-9;   Gmelin:1767;   HMDB:HMDB0000246
 xref_mesh: MESH:C018674
 xref: PMID:12571688;   PMID:1811956;   PMID:1911404;   PMID:19716170;   PMID:21316415;   PMID:21842397;   PMID:2675957;   Reaxys:102391;   UM-BBD_compID:c0019;   Wikipedia:THF



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oxolane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression
ISO NR1I2 protein affects the reaction [tetrahydrofuran results in increased expression of CYP1A2 mRNA]; NR1I3 protein affects the reaction [tetrahydrofuran results in increased expression of CYP1A2 mRNA] CTD PMID:28495613 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases activity
multiple interactions
increases expression
ISO tetrahydrofuran results in increased activity of CYP2B10 protein
NR1I2 protein affects the reaction [tetrahydrofuran results in increased expression of CYP2B10 mRNA]; NR1I3 protein affects the reaction [tetrahydrofuran results in increased expression of CYP2B10 mRNA]
CTD PMID:28495613 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO NR1I2 protein affects the reaction [tetrahydrofuran results in increased expression of CYP1A2 mRNA]; NR1I2 protein affects the reaction [tetrahydrofuran results in increased expression of CYP2B10 mRNA] CTD PMID:28495613 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO NR1I3 protein affects the reaction [tetrahydrofuran results in increased expression of CYP1A2 mRNA]; NR1I3 protein affects the reaction [tetrahydrofuran results in increased expression of CYP2B10 mRNA] CTD PMID:28495613 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19823
    role 19773
      application 19486
        solvent 16640
          polar solvent 15454
            polar aprotic solvent 586
              oxolane 4
                2-(dichloromethyl)tetrahydrofuran 0
                tanegool 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19823
    subatomic particle 19821
      composite particle 19821
        hadron 19821
          baryon 19821
            nucleon 19821
              atomic nucleus 19821
                atom 19821
                  main group element atom 19720
                    p-block element atom 19720
                      carbon group element atom 19643
                        carbon atom 19633
                          organic molecular entity 19633
                            organic molecule 19572
                              organic cyclic compound 19366
                                organic heterocyclic compound 18604
                                  organic heteromonocyclic compound 17116
                                    oxolanes 5475
                                      oxolane 4
                                        2-(dichloromethyl)tetrahydrofuran 0
                                        tanegool 0
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