Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:amsacrine
go back to main search page
Accession:CHEBI:2687 term browser browse the term
Definition:A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
Synonyms:exact_synonym: N-[4-(acridin-9-ylamino)-3-methoxyphenyl]methanesulfonamide
 related_synonym: 4'-(9-Acridinylamino)-3'-methoxymethanesulfonanilide;   4'-(9-Acridinylamino)methanesulfon-m-anisidide;   4'-(9-Acridinylamino)methanesulfon-meta-anisidide;   4'-(9-Acridinylamino)methanesulphon-m-anisidide;   Formula=C21H19N3O3S;   InChI=1S/C21H19N3O3S/c1-27-20-13-14(24-28(2,25)26)11-12-19(20)23-21-15-7-3-5-9-17(15)22-18-10-6-4-8-16(18)21/h3-13,24H,1-2H3,(H,22,23);   InChIKey=XCPGHVQEEXUHNC-UHFFFAOYSA-N;   SMILES=COc1cc(NS(C)(=O)=O)ccc1Nc1c2ccccc2nc2ccccc12;   amsacrina;   amsacrinum;   mAMSA
 xref: Beilstein:500176 "Beilstein";   CAS:51264-14-3 "ChemIDplus";   CAS:51264-14-3 "KEGG COMPOUND";   DrugBank:DB00276;   Drug_Central:203 "DrugCentral";   HMDB:HMDB0014421;   KEGG:C01553;   KEGG:D02321
 xref_mesh: MESH:D000677
 xref: PMID:17675230 "Europe PMC";   PMID:9625435 "Europe PMC";   Reaxys:500176 "Reaxys";   Wikipedia:Amsacrine


show annotations for term's descendants       view all columns           Sort by:
 
amsacrine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:6480464
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Casp2 caspase 2 JBrowse link 4 71,652,358 71,670,228 RGD:6480464
G Ccna2 cyclin A2 JBrowse link 2 123,274,727 123,282,266 RGD:6480464
G Ccnb1 cyclin B1 JBrowse link 2 30,782,133 30,791,106 RGD:6480464
G Ccne1 cyclin E1 JBrowse link 1 94,485,830 94,495,112 RGD:6480464
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:6480464
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Mapk12 mitogen-activated protein kinase 12 JBrowse link 7 130,109,214 130,120,918 RGD:6480464
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:6480464
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:6480464
G Ncl nucleolin JBrowse link 9 93,369,119 93,377,643 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Prc1 protein regulator of cytokinesis 1 JBrowse link 1 142,087,181 142,108,746 RGD:6480464
G Rad51 RAD51 recombinase JBrowse link 3 110,918,240 110,942,920 RGD:6480464
G Rarb retinoic acid receptor, beta JBrowse link 15 9,915,223 10,262,599 RGD:6480464
G Thra thyroid hormone receptor alpha JBrowse link 10 86,657,285 86,684,935 RGD:6480464
G Tnfrsf11b TNF receptor superfamily member 11B JBrowse link 7 93,798,580 93,826,586 RGD:6480464
G Tnfsf11 TNF superfamily member 11 JBrowse link 15 60,482,527 60,512,704 RGD:6480464
G Top2a DNA topoisomerase II alpha JBrowse link 10 86,901,467 86,930,947 RGD:6480464
G Top2b DNA topoisomerase II beta JBrowse link 15 10,262,972 10,319,741 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
G Tp53i3 tumor protein p53 inducible protein 3 JBrowse link 13 75,101,759 75,145,967 RGD:6480464
G Ube2c ubiquitin-conjugating enzyme E2C JBrowse link 3 161,236,971 161,239,371 RGD:6480464
G Wrn WRN RecQ like helicase JBrowse link 16 62,483,773 62,619,018 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19657
    role 19601
      application 19225
        pharmaceutical 19089
          drug 19089
            antineoplastic agent 16561
              amsacrine 28
Path 2
Term Annotations click to browse term
  CHEBI ontology 19657
    subatomic particle 19653
      composite particle 19653
        hadron 19653
          baryon 19653
            nucleon 19653
              atomic nucleus 19653
                atom 19653
                  main group element atom 19534
                    p-block element atom 19534
                      carbon group element atom 19417
                        carbon atom 19409
                          organic molecular entity 19409
                            organic molecule 19332
                              organic cyclic compound 19083
                                organic heterocyclic compound 18154
                                  organic heteropolycyclic compound 17419
                                    organic heterotricyclic compound 13729
                                      dibenzopyridine 140
                                        acridines 107
                                          amsacrine 28
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.