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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:synthetic auxin
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Accession:CHEBI:26841 term browser browse the term
Definition:A synthetic compound exhibiting auxin activity.
Synonyms:related_synonym: synthetic auxins


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(2,4,5-trichlorophenoxy)acetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ABCA7 mRNA CTD PMID:18579281 NCBI chr 7:9,691,452...9,711,466
Ensembl chr 7:9,691,449...9,711,425
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ABCB4 mRNA CTD PMID:9210621 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression
multiple interactions
ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ABCC2 mRNA; 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ABCC2 protein
Alpha-Amanitin inhibits the reaction [2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ABCC2 mRNA]
CTD PMID:10377250 PMID:16426233 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Acap3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of ACAP3 mRNA CTD PMID:18579281 NCBI chr 5:166,500,781...166,515,477
Ensembl chr 5:166,500,781...166,515,481
JBrowse link
G Acer2 alkaline ceramidase 2 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of ACER2 mRNA CTD PMID:18579281 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614
JBrowse link
G Adgrb2 adhesion G protein-coupled receptor B2 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ADGRB2 mRNA CTD PMID:18579281 NCBI chr 5:142,299,190...142,362,540
Ensembl chr 5:142,331,329...142,362,540
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ADH4 mRNA CTD PMID:18579281 NCBI chr 2:226,948,717...226,966,747 JBrowse link
G Alpi alkaline phosphatase, intestinal decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of ALPI mRNA CTD PMID:18579281 NCBI chr 9:87,773,411...87,776,877
Ensembl chr 9:87,773,411...87,776,877
JBrowse link
G Ar androgen receptor affects binding EXP 2,4,5-Trichlorophenoxyacetic Acid binds to AR protein CTD PMID:14565775 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arhgap32 Rho GTPase activating protein 32 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ARHGAP32 mRNA CTD PMID:18579281 NCBI chr 8:30,421,269...30,681,653
Ensembl chr 8:30,421,515...30,678,454
JBrowse link
G Arsg arylsulfatase G increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ARSG mRNA CTD PMID:18579281 NCBI chr10:94,412,261...94,551,224
Ensembl chr10:94,447,399...94,542,941
JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of BASP1 mRNA CTD PMID:18579281 NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043
JBrowse link
G C1qtnf4 C1q and TNF related 4 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of C1QTNF4 mRNA CTD PMID:18579281 NCBI chr 3:76,854,368...76,872,991
Ensembl chr 3:76,857,735...76,874,139
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of CACNB3 mRNA CTD PMID:18579281 NCBI chr 7:129,784,799...129,797,074
Ensembl chr 7:129,783,674...129,797,074
JBrowse link
G Camk1d calcium/calmodulin-dependent protein kinase ID increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of CAMK1D mRNA CTD PMID:18579281 NCBI chr17:72,581,899...72,982,704
Ensembl chr17:72,581,979...72,980,556
JBrowse link
G Capn6 calpain 6 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of CAPN6 mRNA CTD PMID:18579281 NCBI chr  X:107,380,774...107,405,489
Ensembl chr  X:107,380,774...107,405,489
JBrowse link
G Cdh1 cadherin 1 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of CDH1 mRNA CTD PMID:18579281 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cirbp cold inducible RNA binding protein increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of CIRBP mRNA CTD PMID:18579281 NCBI chr 7:9,533,857...9,538,899 JBrowse link
G Ckm creatine kinase, M-type increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of CKM mRNA CTD PMID:18579281 NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720
JBrowse link
G Col15a1 collagen type XV alpha 1 chain increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of COL15A1 mRNA CTD PMID:18579281 NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of CYP7B1 mRNA CTD PMID:18579281 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
JBrowse link
G Ddc dopa decarboxylase increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of DDC mRNA CTD PMID:18579281 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
JBrowse link
G Eepd1 endonuclease/exonuclease/phosphatase family domain containing 1 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of EEPD1 mRNA CTD PMID:18579281 NCBI chr 8:23,957,258...24,064,343
Ensembl chr 8:23,957,255...24,064,340
JBrowse link
G Ephx1 epoxide hydrolase 1 increases activity ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased activity of EPHX1 protein CTD PMID:3032197 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Ephx2 epoxide hydrolase 2 multiple interactions ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of and results in increased activity of EPHX2 protein CTD PMID:3032197 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO 2,4,5-Trichlorophenoxyacetic Acid binds to and results in decreased activity of ESR1 protein CTD PMID:16626760 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Far1 fatty acyl CoA reductase 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of FAR1 mRNA CTD PMID:18579281 NCBI chr 1:167,644,622...167,705,868
Ensembl chr 1:167,644,677...167,705,730
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of FKBP5 mRNA CTD PMID:18579281 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of FMO2 mRNA CTD PMID:18579281 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
JBrowse link
G G0s2 G0/G1switch 2 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of G0S2 mRNA CTD PMID:18579281 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
JBrowse link
G Gbf1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of GBF1 mRNA CTD PMID:18579281 NCBI chr 1:245,018,535...245,147,052
Ensembl chr 1:245,018,568...245,147,042
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of GCLC mRNA
2,4,5-Trichlorophenoxyacetic Acid results in increased expression of GCLC; 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of GCLC mRNA
CTD PMID:10377250 PMID:16426233 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gde1 glycerophosphodiester phosphodiesterase 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of GDE1 mRNA CTD PMID:18579281 NCBI chr 1:173,016,984...173,032,396
Ensembl chr 1:172,954,394...173,032,429
JBrowse link
G Gfra1 GDNF family receptor alpha 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of GFRA1 mRNA CTD PMID:18579281 NCBI chr 1:257,315,682...257,552,004 JBrowse link
G Git2 GIT ArfGAP 2 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of GIT2 mRNA CTD PMID:18579281 NCBI chr12:41,829,717...41,872,621
Ensembl chr12:41,829,730...41,871,097
JBrowse link
G Gmppb GDP-mannose pyrophosphorylase B increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of GMPPB mRNA CTD PMID:18579281 NCBI chr 8:108,737,429...108,767,286
Ensembl chr 8:108,693,060...108,767,286
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of GOT1 mRNA CTD PMID:18579281 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpm6a glycoprotein m6a decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of GPM6A mRNA CTD PMID:18579281 NCBI chr16:36,641,282...36,973,477
Ensembl chr16:36,641,284...36,973,475
JBrowse link
G Gpr12 G protein-coupled receptor 12 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of GPR12 mRNA CTD PMID:18579281 NCBI chr12:8,522,709...8,525,875
Ensembl chr12:8,522,953...8,527,973
JBrowse link
G Gpr85 G protein-coupled receptor 85 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of GPR85 mRNA CTD PMID:18579281 NCBI chr 4:42,100,138...42,109,584
Ensembl chr 4:42,102,941...42,109,566
JBrowse link
G Hapln1 hyaluronan and proteoglycan link protein 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of HAPLN1 mRNA CTD PMID:18579281 NCBI chr 2:20,631,640...20,696,388
Ensembl chr 2:20,631,640...20,693,777
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of HMOX1 mRNA CTD PMID:18579281 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of HSPA8 mRNA CTD PMID:18579281 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of HSPB1 mRNA CTD PMID:18579281 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of HSPH1 mRNA CTD PMID:18579281 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of IDO2 mRNA CTD PMID:18579281 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324
JBrowse link
G Ihh Indian hedgehog signaling molecule increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of IHH mRNA CTD PMID:18579281 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of IKBKE mRNA CTD PMID:18579281 NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143
JBrowse link
G Il1r1 interleukin 1 receptor type 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of IL1R1 mRNA CTD PMID:18579281 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
JBrowse link
G Insc INSC, spindle orientation adaptor protein increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of INSC mRNA CTD PMID:18579281 NCBI chr 1:168,993,032...169,100,438
Ensembl chr 1:168,993,032...169,100,433
JBrowse link
G Klf5 Kruppel-like factor 5 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of KLF5 mRNA CTD PMID:18579281 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
JBrowse link
G Limch1 LIM and calponin homology domains 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of LIMCH1 mRNA CTD PMID:18579281 NCBI chr14:41,112,579...41,425,185
Ensembl chr14:41,114,803...41,425,191
JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of LMCD1 mRNA CTD PMID:18579281 NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046
JBrowse link
G LOC103690086 uncharacterized LOC103690086 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of GBP9 mRNA CTD PMID:18579281
G Lpar4 lysophosphatidic acid receptor 4 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of LPAR4 mRNA CTD PMID:18579281 NCBI chr  X:72,033,486...72,046,978
Ensembl chr  X:72,033,486...72,046,977
JBrowse link
G Lpin1 lipin 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of LPIN1 mRNA CTD PMID:18579281 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
G Lrtm1 leucine-rich repeats and transmembrane domains 1 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of LRTM1 mRNA CTD PMID:18579281 NCBI chr16:4,210,343...4,217,843 JBrowse link
G Matk megakaryocyte-associated tyrosine kinase increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of MATK mRNA CTD PMID:18579281 NCBI chr 7:8,456,990...8,465,947
Ensembl chr 7:8,456,998...8,462,022
JBrowse link
G Mpdz multiple PDZ domain crumbs cell polarity complex component increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of MPDZ mRNA CTD PMID:18579281 NCBI chr 5:95,766,112...95,920,531
Ensembl chr 5:95,766,118...95,920,499
JBrowse link
G Mt1 metallothionein 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of MT1 mRNA CTD PMID:18579281 NCBI chr19:10,826,032...10,827,048 JBrowse link
G Mt4 metallothionein 4 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of MT4 mRNA CTD PMID:18579281 NCBI chr19:10,863,813...10,865,909
Ensembl chr19:10,863,813...10,865,909
JBrowse link
G Mvd mevalonate diphosphate decarboxylase increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of MVD mRNA CTD PMID:18579281 NCBI chr19:50,496,366...50,506,389
Ensembl chr19:50,496,367...50,507,971
JBrowse link
G Mybph myosin binding protein H increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of MYBPH mRNA CTD PMID:18579281 NCBI chr13:45,653,156...45,660,893
Ensembl chr13:45,653,234...45,660,893
JBrowse link
G Ndrg4 NDRG family member 4 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of NDRG4 mRNA CTD PMID:18579281 NCBI chr19:9,351,408...9,387,398
Ensembl chr19:9,351,404...9,386,914
JBrowse link
G Nip7 nucleolar pre-rRNA processing protein NIP7 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of NIP7 mRNA CTD PMID:18579281 NCBI chr19:34,962,557...34,964,700
Ensembl chr19:34,962,557...34,964,711
JBrowse link
G Nrg4 neuregulin 4 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of NRG4 mRNA CTD PMID:18579281 NCBI chr 8:55,586,253...55,677,829
Ensembl chr 8:55,592,893...55,677,483
JBrowse link
G Ogn osteoglycin decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of OGN mRNA CTD PMID:18579281 NCBI chr17:15,032,069...15,052,626
Ensembl chr17:15,032,069...15,052,739
JBrowse link
G Olr346 olfactory receptor 346 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of OLFR1451 mRNA CTD PMID:18579281 NCBI chr 1:210,136,841...210,137,767
Ensembl chr 1:210,132,946...210,138,365
JBrowse link
G Pdzd3 PDZ domain containing 3 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of PDZD3 mRNA CTD PMID:18579281 NCBI chr 8:44,584,390...44,588,838
Ensembl chr 8:44,584,390...44,588,860
JBrowse link
G Pfkp phosphofructokinase, platelet decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of PFKP mRNA CTD PMID:18579281 NCBI chr17:63,729,743...63,794,021
Ensembl chr17:63,729,780...63,794,018
JBrowse link
G Plin4 perilipin 4 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of PLIN4 mRNA CTD PMID:18579281 NCBI chr 9:929,168...938,062
Ensembl chr 9:929,176...938,056
JBrowse link
G Por cytochrome p450 oxidoreductase decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of POR mRNA CTD PMID:18579281 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Ppfibp1 PPFIA binding protein 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of PPFIBP1 mRNA CTD PMID:18579281 NCBI chr 4:179,807,579...179,951,428
Ensembl chr 4:179,808,794...179,951,428
JBrowse link
G Ppp1r3a protein phosphatase 1, regulatory subunit 3A decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of PPP1R3A mRNA CTD PMID:18579281 NCBI chr 4:42,937,353...42,980,195
Ensembl chr 4:42,939,599...42,980,638
JBrowse link
G Ppp1r3g protein phosphatase 1, regulatory subunit 3G decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of PPP1R3G mRNA CTD PMID:18579281 NCBI chr17:28,874,956...28,878,288
Ensembl chr17:28,876,482...28,877,525
JBrowse link
G Prok1 prokineticin 1 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of PROK1 mRNA CTD PMID:18579281 NCBI chr 2:194,853,991...194,859,250
Ensembl chr 2:194,853,991...194,859,250
JBrowse link
G Prr9 proline rich 9 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of PRR9 mRNA CTD PMID:18579281 NCBI chr 2:177,599,483...177,600,849
Ensembl chr 2:177,599,483...177,600,849
JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4A1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of PTP4A1 mRNA CTD PMID:18579281 NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:33,214,208...33,221,964
JBrowse link
G Retreg1 reticulophagy regulator 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of RETREG1 mRNA CTD PMID:18579281 NCBI chr 2:76,335,609...76,474,817 JBrowse link
G Rprd1a regulation of nuclear pre-mRNA domain containing 1A decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of RPRD1A mRNA CTD PMID:18579281 NCBI chr18:15,791,418...15,839,338
Ensembl chr18:15,791,418...15,839,338
JBrowse link
G Selenop selenoprotein P decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of SELENOP mRNA CTD PMID:18579281 NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852
JBrowse link
G Sema3c semaphorin 3C decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of SEMA3C mRNA CTD PMID:18579281 NCBI chr 4:17,583,212...17,747,234
Ensembl chr 4:17,583,212...17,746,534
JBrowse link
G Sgk2 serum/glucocorticoid regulated kinase 2 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of SGK2 mRNA CTD PMID:18579281 NCBI chr 3:151,644,102...151,669,480
Ensembl chr 3:151,644,102...151,669,480
JBrowse link
G Slc24a2 solute carrier family 24 member 2 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of SLC24A2 mRNA CTD PMID:18579281 NCBI chr 5:101,499,536...101,739,337
Ensembl chr 5:101,502,278...101,739,337
JBrowse link
G Slc25a32 solute carrier family 25 member 32 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of SLC25A32 mRNA CTD PMID:18579281 NCBI chr 7:70,142,958...70,160,726
Ensembl chr 7:70,142,964...70,160,770
JBrowse link
G Slc66a1 solute carrier family 66 member 1 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of SLC66A1 mRNA CTD PMID:18579281 NCBI chr 5:151,537,870...151,552,338
Ensembl chr 5:151,542,376...151,552,259
JBrowse link
G Slc6a15 solute carrier family 6 member 15 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of SLC6A15 mRNA CTD PMID:18579281 NCBI chr 7:38,553,055...38,607,239
Ensembl chr 7:38,553,196...38,607,239
JBrowse link
G Snx7 sorting nexin 7 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of SNX7 mRNA CTD PMID:18579281 NCBI chr 2:205,843,164...205,927,737
Ensembl chr 2:205,842,837...205,927,763
JBrowse link
G Spon2 spondin 2 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of SPON2 mRNA CTD PMID:18579281 NCBI chr14:77,505,695...77,518,001
Ensembl chr14:77,511,901...77,517,996
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of SREBF1 mRNA CTD PMID:18579281 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Svil supervillin increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of SVIL mRNA CTD PMID:18579281 NCBI chr17:52,648,502...52,844,114
Ensembl chr17:52,648,502...52,793,404
JBrowse link
G Tacc2 transforming, acidic coiled-coil containing protein 2 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of TACC2 mRNA CTD PMID:18579281 NCBI chr 1:185,139,223...185,327,881
Ensembl chr 1:185,116,111...185,327,881
JBrowse link
G Tbc1d8 TBC1 domain family, member 8 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of TBC1D8 mRNA CTD PMID:18579281 NCBI chr 9:41,651,394...41,761,432
Ensembl chr 9:41,651,395...41,761,409
JBrowse link
G Tcea2 transcription elongation factor A2 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of TCEA2 mRNA CTD PMID:18579281 NCBI chr 3:168,796,244...168,804,125
Ensembl chr 3:168,796,331...168,804,116
JBrowse link
G Thra thyroid hormone receptor alpha increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of THRA mRNA CTD PMID:18579281 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link
G Thrb thyroid hormone receptor beta affects binding ISO 2,4,5-Trichlorophenoxyacetic Acid binds to THRB protein CTD PMID:27410513 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link
G Tom1l2 target of myb1 like 2 membrane trafficking protein decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of TOM1L2 mRNA CTD PMID:18579281 NCBI chr10:45,036,034...45,158,168
Ensembl chr10:45,036,035...45,158,032
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of TRIB3 mRNA CTD PMID:18579281 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
JBrowse link
G Tril TLR4 interactor with leucine-rich repeats decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of TRIL mRNA CTD PMID:18579281 NCBI chr 4:82,922,327...82,927,172
Ensembl chr 4:82,922,328...82,927,172
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of TSC22D1 mRNA CTD PMID:18579281 NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958
JBrowse link
G Ugt2a3 UDP glucuronosyltransferase family 2 member A3 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of UGT2A3 mRNA CTD PMID:18579281 NCBI chr14:20,572,825...20,590,295
Ensembl chr14:20,572,808...20,590,729
JBrowse link
G Usp2 ubiquitin specific peptidase 2 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of USP2 mRNA CTD PMID:18579281 NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of VCAM1 mRNA CTD PMID:18579281 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Veph1 ventricular zone expressed PH domain-containing 1 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of VEPH1 mRNA CTD PMID:18579281 NCBI chr 2:150,291,379...150,537,491
Ensembl chr 2:150,296,573...150,537,266
JBrowse link
G Wars2 tryptophanyl tRNA synthetase 2 (mitochondrial) increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of WARS2 mRNA CTD PMID:18579281 NCBI chr 2:186,459,744...186,543,581
Ensembl chr 2:186,459,444...186,543,571
JBrowse link
(4-chloro-2-methylphenoxy)acetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcnka chloride voltage-gated channel Ka decreases activity EXP 2-Methyl-4-chlorophenoxyacetic Acid analog results in decreased activity of CLCNKA protein CTD PMID:15167890 NCBI chr 5:153,691,208...153,706,295
Ensembl chr 5:153,691,209...153,706,148
JBrowse link
G Clcnkb chloride voltage-gated channel Kb decreases activity EXP 2-Methyl-4-chlorophenoxyacetic Acid analog results in decreased activity of CLCNKB protein CTD PMID:15167890 NCBI chr 5:153,710,086...153,733,162
Ensembl chr 5:153,710,094...153,732,153
JBrowse link
G Slc1a2 solute carrier family 1 member 2 affects expression EXP 2-Methyl-4-chlorophenoxyacetic Acid affects the expression of SLC1A2 protein CTD PMID:16019039 NCBI chr 3:89,005,129...89,126,498
Ensembl chr 3:89,005,129...89,126,498
JBrowse link
G Tnf tumor necrosis factor increases expression ISO 2-Methyl-4-chlorophenoxyacetic Acid results in increased expression of TNF protein CTD PMID:10883730 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
1-naphthaleneacetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ces2c carboxylesterase 2C increases hydrolysis ISO CES2C protein results in increased hydrolysis of 1-naphthaleneacetic acid CTD PMID:22513142 NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790
JBrowse link
G Ifng interferon gamma increases expression ISO 1-naphthaleneacetic acid results in increased expression of IFNG CTD PMID:20728597 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il2 interleukin 2 increases expression ISO 1-naphthaleneacetic acid results in increased expression of IL2 CTD PMID:20728597 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha increases expression ISO 1-naphthaleneacetic acid results in increased expression of IL2RA CTD PMID:20728597 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
JBrowse link
G Tnf tumor necrosis factor increases expression ISO 1-naphthaleneacetic acid results in increased expression of TNF CTD PMID:20728597 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 increases glucuronidation EXP UGT2B1 protein results in increased glucuronidation of 1-naphthaleneacetic acid CTD PMID:8302279 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
2,4-D term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of ABCB4 mRNA CTD PMID:9210621 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Alb albumin affects binding ISO 2,4-Dichlorophenoxyacetic Acid binds to ALB protein CTD PMID:9877224 PMID:11451446 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 multiple interactions
decreases expression
ISO [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of APAF1 mRNA; [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of APAF1 protein
2,4-Dichlorophenoxyacetic Acid results in decreased expression of APAF1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in decreased expression of APAF1 protein
CTD PMID:33865415 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Ar androgen receptor multiple interactions ISO 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [Androgens binds to AR protein]; 2,4-Dichlorophenoxyacetic Acid promotes the reaction [Dihydrotestosterone results in increased localization of and results in increased activity of AR protein] CTD PMID:16107550 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Ccdc120 coiled-coil domain containing 120 decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of CCDC120 mRNA CTD PMID:15878651 NCBI chr  X:14,753,594...14,772,745
Ensembl chr  X:14,753,696...14,772,743
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of CCL11 protein CTD PMID:19467290 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of CCL2 protein CTD PMID:19467290 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of CCL4 protein CTD PMID:19467290 NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Cdk6 cyclin-dependent kinase 6 increases expression
multiple interactions
ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of CDK6 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of CDK6 protein
[Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CDK6 mRNA; [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CDK6 protein
CTD PMID:33865415 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Cldn1 claudin 1 decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of CLDN1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in decreased expression of CLDN1 protein CTD PMID:28699141 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
JBrowse link
G Clk1 CDC-like kinase 1 decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of CLK1 mRNA CTD PMID:15878651 NCBI chr 9:59,947,774...59,959,002
Ensembl chr 9:59,947,764...59,957,000
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of CNP protein CTD PMID:18460445 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720
JBrowse link
G Crat carnitine O-acetyltransferase increases activity ISO 2,4-Dichlorophenoxyacetic Acid results in increased activity of CRAT protein CTD PMID:1755024 NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression
multiple interactions
ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of CREB1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of CREB1 protein
PPARB protein affects the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CREB1 mRNA]
CTD PMID:29633193 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 affects expression ISO 2,4-Dichlorophenoxyacetic Acid affects the expression of CYP17A1 mRNA CTD PMID:26838045 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of CYP1A1 mRNA CTD PMID:10910964 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of CYP1A2 mRNA CTD PMID:10910964 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of CYP1B1 mRNA CTD PMID:10910964 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Dbh dopamine beta-hydroxylase decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of DBH protein CTD PMID:16931444 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
JBrowse link
G Dclre1c DNA cross-link repair 1C increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of DCLRE1C mRNA CTD PMID:15878651 NCBI chr17:74,775,828...74,810,089
Ensembl chr17:74,776,935...74,809,186
JBrowse link
G Ddb2 damage specific DNA binding protein 2 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of DDB2 mRNA CTD PMID:15878651 NCBI chr 3:77,185,114...77,207,650
Ensembl chr 3:77,185,109...77,207,631
JBrowse link
G Ephx1 epoxide hydrolase 1 increases activity ISO 2,4-Dichlorophenoxyacetic Acid results in increased activity of EPHX1 protein CTD PMID:3032197 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Ephx2 epoxide hydrolase 2 increases activity ISO 2,4-Dichlorophenoxyacetic Acid results in increased activity of EPHX2 protein CTD PMID:1755024 PMID:3032197 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Foxo1 forkhead box O1 multiple interactions
increases expression
ISO PPARB protein affects the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of FOXO1 mRNA]
2,4-Dichlorophenoxyacetic Acid results in increased expression of FOXO1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of FOXO1 protein
CTD PMID:29633193 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of FTH1 mRNA CTD PMID:15878651 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of FTL mRNA CTD PMID:15878651 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725
JBrowse link
G Gfap glial fibrillary acidic protein increases expression EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of GFAP mRNA CTD PMID:22954530 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of HMGCR CTD PMID:26838045 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of HMGCS1 CTD PMID:26838045 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Ifng interferon gamma increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of IFNG CTD PMID:20728597 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of IL1RL1 mRNA CTD PMID:15878651 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256
JBrowse link
G Il2 interleukin 2 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of IL2 CTD PMID:20728597 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of IL2RA CTD PMID:20728597 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
JBrowse link
G Il4 interleukin 4 increases expression
increases secretion
ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of IL4 protein
2,4-Dichlorophenoxyacetic Acid results in increased secretion of IL4 protein
CTD PMID:19467290 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il5 interleukin 5 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of IL5 protein CTD PMID:19467290 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Il6 interleukin 6 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of IL6 protein CTD PMID:19467290 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Itgb1 integrin subunit beta 1 increases expression
multiple interactions
ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of ITGB1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of ITGB1 protein
[Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of ITGB1 mRNA; [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of ITGB1 protein
CTD PMID:33865415 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Ldha lactate dehydrogenase A decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of LDHA mRNA; 2,4-Dichlorophenoxyacetic Acid results in decreased expression of LDHA protein CTD PMID:23538319 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
JBrowse link
G Mbp myelin basic protein decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of MBP protein CTD PMID:18460445 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases methylation ISO 2,4-Dichlorophenoxyacetic Acid results in decreased methylation of MYC promoter CTD PMID:11857776 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
increases expression
ISO [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of NFKB1 mRNA; [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of NFKB1 protein
2,4-Dichlorophenoxyacetic Acid results in increased expression of NFKB1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of NFKB1 protein
CTD PMID:33865415 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO 2,4-Dichlorophenoxyacetic Acid binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Ocln occludin decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of OCLN mRNA CTD PMID:28699141 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide decreases secretion EXP 2,4-Dichlorophenoxyacetic Acid results in decreased secretion of OXT protein CTD PMID:20122984 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of PCNA mRNA CTD PMID:15878651 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pfkm phosphofructokinase, muscle decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of PFKM mRNA; 2,4-Dichlorophenoxyacetic Acid results in decreased expression of PFKM protein CTD PMID:23538319 NCBI chr 7:129,221,679...129,259,192
Ensembl chr 7:129,221,653...129,259,192
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases response to substance ISO PPARA protein results in increased susceptibility to 2,4-Dichlorophenoxyacetic Acid CTD PMID:26838045 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta multiple interactions
increases expression
ISO PPARB protein affects the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CREB1 mRNA]; PPARB protein affects the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of FOXO1 mRNA]
2,4-Dichlorophenoxyacetic Acid results in increased expression of PPARB mRNA
CTD PMID:29633193 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Prl prolactin decreases secretion EXP 2,4-Dichlorophenoxyacetic Acid results in decreased secretion of PRL protein CTD PMID:20122984 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Ptger3 prostaglandin E receptor 3 decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of PTGER3 mRNA CTD PMID:15878651 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
JBrowse link
G Slc16a3 solute carrier family 16 member 3 decreases expression
increases expression
EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of SLC16A3 mRNA
2,4-Dichlorophenoxyacetic Acid results in increased expression of SLC16A3 mRNA
CTD PMID:23538319 NCBI chr10:106,212,679...106,222,564
Ensembl chr10:106,212,778...106,222,562
JBrowse link
G Slc22a12 solute carrier family 22 member 12 multiple interactions ISO Potassium promotes the reaction [SLC22A12 protein results in increased uptake of 2,4-Dichlorophenoxyacetic Acid] CTD PMID:15284287 NCBI chr 1:203,845,039...203,852,496
Ensembl chr 1:203,845,048...203,853,555
JBrowse link
G Slc22a20 solute carrier family 22 member 20 multiple interactions ISO 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [SLC22A20 protein results in increased uptake of estrone sulfate] CTD PMID:16478971 NCBI chr 1:203,257,374...203,273,848
Ensembl chr 1:203,257,374...203,273,822
JBrowse link
G Slc22a6 solute carrier family 22 member 6 increases uptake
multiple interactions
EXP
ISO
SLC22A6 protein results in increased uptake of 2,4-Dichlorophenoxyacetic Acid
p-Aminohippuric Acid inhibits the reaction [SLC22A6 protein results in increased uptake of 2,4-Dichlorophenoxyacetic Acid]
CTD PMID:16857889 PMID:17255469 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
JBrowse link
G Slc2a3 solute carrier family 2 member 3 decreases expression
increases expression
EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of SLC2A3 mRNA; 2,4-Dichlorophenoxyacetic Acid results in decreased expression of SLC2A3 protein
2,4-Dichlorophenoxyacetic Acid results in increased expression of SLC2A3 mRNA
CTD PMID:23538319 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472
JBrowse link
G Th tyrosine hydroxylase increases expression EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of TH protein CTD PMID:16931444 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Thrb thyroid hormone receptor beta affects binding ISO 2,4-Dichlorophenoxyacetic Acid binds to THRB protein CTD PMID:27410513 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link
G Tjp1 tight junction protein 1 decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of TJP1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in decreased expression of TJP1 protein CTD PMID:28699141 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
JBrowse link
G Tnf tumor necrosis factor increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of TNF CTD PMID:20728597 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
ISO [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of TRP53 mRNA; [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of TRP53 protein
2,4-Dichlorophenoxyacetic Acid results in increased expression of TRP53 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of TRP53 protein
CTD PMID:33865415 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Usp19 ubiquitin specific peptidase 19 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of USP19 mRNA CTD PMID:15878651 NCBI chr 8:109,190,727...109,201,761
Ensembl chr 8:109,190,724...109,201,741
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of VEGFA mRNA CTD PMID:15878651 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
dicamba term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox1 acyl-CoA oxidase 1 increases activity EXP Dicamba results in increased activity of ACOX1 protein CTD PMID:7657066 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO Dicamba inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein] CTD PMID:29782964 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Alb albumin multiple interactions EXP [bentazone co-treated with Dicamba] results in increased secretion of ALB protein CTD PMID:25863332 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Ins2 insulin 2 multiple interactions ISO Dicamba inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein] CTD PMID:29782964 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
picloram term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxo1 forkhead box O1 decreases expression
multiple interactions
ISO Picloram results in decreased expression of FOXO1 mRNA
arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide promotes the reaction [Picloram results in decreased expression of FOXO1 mRNA]
CTD PMID:21318024 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 decreases expression
multiple interactions
ISO Picloram results in decreased expression of GRIN1 mRNA
arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide promotes the reaction [Picloram results in decreased expression of GRIN1 mRNA]
CTD PMID:21318024 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 multiple interactions
decreases expression
ISO arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide promotes the reaction [Picloram results in decreased expression of ATP6 mRNA] CTD PMID:21318024 Ensembl chr MT:7,919...8,599 JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I decreases expression
multiple interactions
ISO Picloram results in decreased expression of COX1 mRNA
arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide promotes the reaction [Picloram results in decreased expression of COX1 mRNA]
CTD PMID:21318024 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b multiple interactions
decreases expression
ISO arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide promotes the reaction [Picloram results in decreased expression of CYTB mRNA] CTD PMID:21318024 NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
JBrowse link
G Mt-nd1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 multiple interactions
decreases expression
ISO arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of ND1 mRNA] CTD PMID:21318024 NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO Picloram results in increased expression of PPARGC1A mRNA CTD PMID:21318024 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions
decreases expression
ISO arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX1 mRNA] CTD PMID:21318024 NCBI chr 5:130,147,276...130,162,850
Ensembl chr 5:130,147,204...130,162,856
JBrowse link
G Prdx2 peroxiredoxin 2 multiple interactions
decreases expression
ISO arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX2 mRNA] CTD PMID:21318024 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
JBrowse link
G Prdx3 peroxiredoxin 3 multiple interactions
decreases expression
ISO arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX3 mRNA] CTD PMID:21318024 NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
JBrowse link
G Prdx4 peroxiredoxin 4 multiple interactions
decreases expression
ISO arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX4 mRNA] CTD PMID:21318024 NCBI chr  X:40,026,762...40,044,066
Ensembl chr  X:40,026,651...40,044,066
JBrowse link
G Prdx5 peroxiredoxin 5 decreases expression
multiple interactions
ISO Picloram results in decreased expression of PRDX5 mRNA
arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX5 mRNA]
CTD PMID:21318024 NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268
JBrowse link
G Prdx6 peroxiredoxin 6 multiple interactions
decreases expression
ISO arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX6 mRNA] CTD PMID:21318024 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        xenobiotic 18452
          synthetic auxin 182
            (2,4,5-trichlorophenoxy)acetic acid 105
            (4-chloro-2-methylphenoxy)acetic acid 4
            (R)-dichlorprop + 0
            1-naphthaleneacetamide 0
            1-naphthaleneacetic acid 6
            2,3,6-TBA 0
            2,4-D 62
            2,4-D choline 0
            2,4-DB + 0
            4-(2,4-dichlorophenoxy)butanoate 0
            aminocyclopyrachlor + 0
            aminocyclopyrachlor-methyl 0
            benazolin + 0
            benazolin-dimethylammonium 0
            benazolin-ethyl 0
            benazolin-potassium 0
            chlorfenac 0
            chlorfenac(1-) + 0
            chlorfenac-ammonium 0
            chlorfenac-sodium 0
            dicamba 4
            dichlorprop 0
            florpyrauxifen + 0
            florpyrauxifen-benzyl 0
            halauxifen + 0
            halauxifen-methyl 0
            picloram + 13
            quinclorac + 0
            quinclorac-dimethylammonium 0
            quinmerac 0
            tricamba 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        pharmacological role 18847
          agonist 18266
            hormone 18081
              plant hormone 4934
                auxin 1289
                  synthetic auxin 182
                    (2,4,5-trichlorophenoxy)acetic acid 105
                    (4-chloro-2-methylphenoxy)acetic acid 4
                    (R)-dichlorprop + 0
                    1-naphthaleneacetamide 0
                    1-naphthaleneacetic acid 6
                    2,3,6-TBA 0
                    2,4-D 62
                    2,4-D choline 0
                    2,4-DB + 0
                    4-(2,4-dichlorophenoxy)butanoate 0
                    aminocyclopyrachlor + 0
                    aminocyclopyrachlor-methyl 0
                    benazolin + 0
                    benazolin-dimethylammonium 0
                    benazolin-ethyl 0
                    benazolin-potassium 0
                    chlorfenac 0
                    chlorfenac(1-) + 0
                    chlorfenac-ammonium 0
                    chlorfenac-sodium 0
                    dicamba 4
                    dichlorprop 0
                    florpyrauxifen + 0
                    florpyrauxifen-benzyl 0
                    halauxifen + 0
                    halauxifen-methyl 0
                    picloram + 13
                    quinclorac + 0
                    quinclorac-dimethylammonium 0
                    quinmerac 0
                    tricamba 0
paths to the root