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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:steroid alkaloid
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Accession:CHEBI:26767 term browser browse the term
Synonyms:related_synonym: steroidal alkaloids


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solasodine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO solasodine results in decreased phosphorylation of AKT1 protein CTD PMID:28283413 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Bche butyrylcholinesterase decreases activity ISO solasodine results in decreased activity of BCHE protein CTD PMID:31152736 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bsg basigin (Ok blood group) decreases expression ISO solasodine results in decreased expression of BSG mRNA CTD PMID:28283413 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP solasodine inhibits the reaction [Ovalbumin results in increased secretion of IL1B protein] CTD PMID:36084726 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il4 interleukin 4 multiple interactions EXP solasodine inhibits the reaction [Ovalbumin results in increased secretion of IL4 protein] CTD PMID:36084726 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il5 interleukin 5 multiple interactions EXP solasodine inhibits the reaction [Ovalbumin results in increased secretion of IL5 protein] CTD PMID:36084726 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Mir21 microRNA 21 decreases expression ISO solasodine results in decreased expression of MIR21 mRNA CTD PMID:28283413 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO solasodine results in decreased expression of MMP2 mRNA CTD PMID:28283413 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression ISO solasodine results in decreased expression of MMP9 mRNA CTD PMID:28283413 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs increases expression ISO solasodine results in increased expression of RECK mRNA CTD PMID:28283413 NCBI chr 5:58,102,961...58,169,516
Ensembl chr 5:58,102,981...58,169,502 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO solasodine results in increased expression of TIMP1 mRNA CTD PMID:28283413 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression ISO solasodine results in increased expression of TIMP2 mRNA CTD PMID:28283413 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP solasodine inhibits the reaction [Ovalbumin results in increased secretion of TNF protein] CTD PMID:36084726 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19921
    role 19896
      biological role 19894
        biochemical role 19584
          metabolite 19568
            alkaloid 7809
              steroid alkaloid 13
                (+)-buxaminol C 0
                (3S,10R,13S,17R)-3-Hydroxy-10,13-dimethyl-17-[1-(3-methyl-2,3,4,5-tetrahydropyridin-6-yl)ethyl]-1,2,3,4,5,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-6-one 0
                22-iso-teinemine 0
                25-iso-etioline 0
                31-demethylbuxaminol 0
                5,6-dehydrotomatine 0
                Buxalongifolamidine 0
                Buxamine A 0
                Buxamine E 0
                Conessine dihydrobromide 0
                Cyclobuxine D 0
                Cyclobuxophylline K 0
                Cycloprotobuxine C 0
                Cyclovirobuxine C 0
                Etioline 0
                LSM-6454 0
                Samandenone 0
                Solacapine 0
                Solacongestidine 0
                Solanocapsine 0
                Teinemine 0
                buxaminol A 0
                conessine 0
                cortistatins + 0
                cyclonataminol 0
                esculeoside A 0
                hookerianamide H 0
                hookerianamide I 0
                hookerianamide J 0
                hookerianamide K 0
                solasodine + 13
                tomatine + 0
                wrightiamine A 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19921
    subatomic particle 19919
      composite particle 19919
        hadron 19919
          baryon 19919
            nucleon 19919
              atomic nucleus 19919
                atom 19919
                  main group element atom 19867
                    p-block element atom 19867
                      carbon group element atom 19812
                        carbon atom 19807
                          organic molecular entity 19807
                            organic molecule 19764
                              organic cyclic compound 19572
                                organic polycyclic compound 17264
                                  steroid 14701
                                    steroid alkaloid 13
                                      (+)-buxaminol C 0
                                      (3S,10R,13S,17R)-3-Hydroxy-10,13-dimethyl-17-[1-(3-methyl-2,3,4,5-tetrahydropyridin-6-yl)ethyl]-1,2,3,4,5,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-6-one 0
                                      22-iso-teinemine 0
                                      25-iso-etioline 0
                                      31-demethylbuxaminol 0
                                      5,6-dehydrotomatine 0
                                      Buxalongifolamidine 0
                                      Buxamine A 0
                                      Buxamine E 0
                                      Conessine dihydrobromide 0
                                      Cyclobuxine D 0
                                      Cyclobuxophylline K 0
                                      Cycloprotobuxine C 0
                                      Cyclovirobuxine C 0
                                      Etioline 0
                                      LSM-6454 0
                                      Samandenone 0
                                      Solacapine 0
                                      Solacongestidine 0
                                      Solanocapsine 0
                                      Teinemine 0
                                      buxaminol A 0
                                      conessine 0
                                      cortistatins + 0
                                      cyclonataminol 0
                                      esculeoside A 0
                                      hookerianamide H 0
                                      hookerianamide I 0
                                      hookerianamide J 0
                                      hookerianamide K 0
                                      solasodine + 13
                                      tomatine + 0
                                      wrightiamine A 0
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