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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:sterigmatocystins
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Accession:CHEBI:26759 term browser browse the term


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sterigmatocystin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcf1 ATP binding cassette subfamily F member 1 increases expression ISO Sterigmatocystin results in increased expression of ABCF1 mRNA CTD PMID:19818335 NCBI chr20:2,802,519...2,815,433
Ensembl chr20:2,802,488...2,815,433 		JBrowse link
G Aimp1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 increases expression ISO Sterigmatocystin results in increased expression of AIMP1 mRNA CTD PMID:19818335 NCBI chr 2:221,151,907...221,175,458
Ensembl chr 2:221,151,904...221,175,728 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein increases expression EXP Sterigmatocystin results in increased expression of ARC mRNA CTD PMID:34126181 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Atm ATM serine/threonine kinase increases expression
multiple interactions		 ISO Sterigmatocystin results in increased expression of ATM protein modified form
2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Sterigmatocystin results in increased expression of ATM protein modified form]		 CTD PMID:26914363 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atr ATR serine/threonine kinase increases phosphorylation
multiple interactions		 ISO Sterigmatocystin results in increased phosphorylation of ATR protein
ATR protein promotes the reaction [Sterigmatocystin results in increased phosphorylation of CHEK1 protein]		 CTD PMID:26914363 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Sterigmatocystin results in increased expression of BAX mRNA CTD PMID:32553934 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Sterigmatocystin results in decreased expression of BCL2 mRNA CTD PMID:32553934 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression EXP Sterigmatocystin results in increased expression of BDNF mRNA CTD PMID:34126181 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Blvrb biliverdin reductase B increases expression ISO Sterigmatocystin results in increased expression of BLVRB mRNA CTD PMID:21356202 NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375 		JBrowse link
G Calb2 calbindin 2 decreases expression EXP Sterigmatocystin results in decreased expression of CALB2 mRNA CTD PMID:34126181 NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438 		JBrowse link
G Casp1 caspase 1 increases expression ISO Sterigmatocystin results in increased expression of CASP1 mRNA CTD PMID:19818335 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp3 caspase 3 increases expression ISO Sterigmatocystin results in increased expression of CASP3 mRNA CTD PMID:32553934 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase decreases expression EXP Sterigmatocystin results in decreased expression of CAT mRNA CTD PMID:34126181 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl1 C-C motif chemokine ligand 1 increases expression ISO Sterigmatocystin results in increased expression of CCL1 mRNA CTD PMID:19818335 NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 increases expression ISO Sterigmatocystin results in increased expression of CCL19 mRNA CTD PMID:19818335 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 decreases expression ISO Sterigmatocystin results in decreased expression of CCL20 mRNA CTD PMID:19818335 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccl22 C-C motif chemokine ligand 22 increases expression ISO Sterigmatocystin results in increased expression of CCL22 mRNA CTD PMID:19818335 NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400 		JBrowse link
G Ccl25 C-C motif chemokine ligand 25 increases expression ISO Sterigmatocystin results in increased expression of CCL25 mRNA CTD PMID:19818335 NCBI chr12:2,707,398...2,716,571
Ensembl chr12:2,707,398...2,716,554 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 affects expression
increases expression		 ISO Sterigmatocystin affects the expression of CCL3 mRNA
Sterigmatocystin results in increased expression of CCL3 protein		 CTD PMID:21356202 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccnb1 cyclin B1 increases expression
multiple interactions		 ISO Sterigmatocystin results in increased expression of CCNB1 mRNA; Sterigmatocystin results in increased expression of CCNB1 protein
MLH1 protein affects the reaction [Sterigmatocystin results in increased expression of CCNB1 protein]; Sterigmatocystin results in decreased expression of [CCNB1 protein binds to CDK1 protein]		 CTD PMID:23296099 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP Sterigmatocystin results in decreased expression of CCND1 mRNA CTD PMID:34126181 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd2 cyclin D2 increases expression EXP Sterigmatocystin results in increased expression of CCND2 mRNA CTD PMID:34126181 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 increases expression ISO Sterigmatocystin results in increased expression of CCR1 mRNA CTD PMID:19818335 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Ccr10 C-C motif chemokine receptor 10 increases expression ISO Sterigmatocystin results in increased expression of CCR10 mRNA CTD PMID:19818335 NCBI chr10:86,108,551...86,110,988
Ensembl chr10:86,108,551...86,110,988 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression ISO Sterigmatocystin results in increased expression of CCR2 mRNA CTD PMID:19818335 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Ccr4 C-C motif chemokine receptor 4 increases expression ISO Sterigmatocystin results in increased expression of CCR4 mRNA CTD PMID:19818335 NCBI chr 8:114,176,291...114,182,033
Ensembl chr 8:114,176,974...114,178,056 		JBrowse link
G Ccr6 C-C motif chemokine receptor 6 increases expression ISO Sterigmatocystin results in increased expression of CCR6 mRNA CTD PMID:19818335 NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 increases expression ISO Sterigmatocystin results in increased expression of CCR7 mRNA CTD PMID:19818335 NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309 		JBrowse link
G Ccr8 C-C motif chemokine receptor 8 increases expression ISO Sterigmatocystin results in increased expression of CCR8 mRNA CTD PMID:19818335 NCBI chr 8:119,826,332...119,828,292
Ensembl chr 8:119,826,568...119,827,629 		JBrowse link
G Ccr9 C-C motif chemokine receptor 9 increases expression ISO Sterigmatocystin results in increased expression of CCR9 mRNA CTD PMID:19818335 NCBI chr 8:123,396,157...123,410,199
Ensembl chr 8:123,395,813...123,413,969 		JBrowse link
G Cd40lg CD40 ligand increases expression ISO Sterigmatocystin results in increased expression of CD40LG mRNA CTD PMID:19818335 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Cdc25c cell division cycle 25C multiple interactions
increases expression		 ISO MLH1 protein affects the reaction [Sterigmatocystin results in increased expression of CDC25C protein modified form]; MLH1 protein affects the reaction [Sterigmatocystin results in increased expression of CDC25C protein]
Sterigmatocystin results in increased expression of CDC25C mRNA; Sterigmatocystin results in increased expression of CDC25C protein; Sterigmatocystin results in increased expression of CDC25C protein modified form		 CTD PMID:23296099 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions
increases expression
decreases expression		 ISO
EXP		 MLH1 protein affects the reaction [Sterigmatocystin results in increased expression of CDK1 protein modified form]; MLH1 protein affects the reaction [Sterigmatocystin results in increased expression of CDK1 protein]; Sterigmatocystin results in decreased expression of [CCNB1 protein binds to CDK1 protein]
Sterigmatocystin results in increased expression of CDK1 mRNA; Sterigmatocystin results in increased expression of CDK1 protein; Sterigmatocystin results in increased expression of CDK1 protein modified form
Sterigmatocystin results in decreased expression of CDK1 mRNA		 CTD PMID:23296099 PMID:34126181 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdk2 cyclin dependent kinase 2 affects expression EXP Sterigmatocystin affects the expression of CDK2 mRNA CTD PMID:34126181 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression EXP Sterigmatocystin results in decreased expression of CDKN1A mRNA CTD PMID:34126181 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases expression EXP Sterigmatocystin results in decreased expression of CDKN1B mRNA CTD PMID:34126181 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C affects expression EXP Sterigmatocystin affects the expression of CDKN1C mRNA CTD PMID:34126181 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B affects expression EXP Sterigmatocystin affects the expression of CDKN2B mRNA CTD PMID:34126181 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050 		JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C increases expression EXP Sterigmatocystin results in increased expression of CDKN2C mRNA CTD PMID:34126181 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278 		JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions
increases expression		 ISO ATR protein promotes the reaction [Sterigmatocystin results in increased phosphorylation of CHEK1 protein]; Sterigmatocystin results in increased expression of and results in increased phosphorylation of CHEK1 protein
Sterigmatocystin results in increased expression of CHEK1 protein modified form		 CTD PMID:26914363 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009 		JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions
increases expression		 ISO 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Sterigmatocystin results in increased expression of CHEK2 protein modified form] CTD PMID:26914363 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit increases expression EXP Sterigmatocystin results in increased expression of CHRNA7 mRNA CTD PMID:34126181 NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit decreases expression EXP Sterigmatocystin results in decreased expression of CHRNB2 mRNA CTD PMID:34126181 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Crp C-reactive protein increases expression ISO Sterigmatocystin results in increased expression of CRP mRNA CTD PMID:19818335 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression ISO Sterigmatocystin results in increased expression of CX3CL1 mRNA CTD PMID:19818335 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression
increases expression		 ISO Sterigmatocystin results in decreased expression of CXCL10 mRNA
Sterigmatocystin results in increased expression of CXCL10 protein		 CTD PMID:19818335 PMID:21356202 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 decreases expression ISO Sterigmatocystin results in decreased expression of CXCL11 mRNA CTD PMID:19818335 NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO Sterigmatocystin results in increased expression of CXCL12 mRNA CTD PMID:19818335 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 increases expression ISO Sterigmatocystin results in increased expression of CXCL13 mRNA CTD PMID:19818335 NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO Sterigmatocystin results in increased expression of CXCL2 mRNA CTD PMID:21356202 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 affects expression
increases expression		 ISO Sterigmatocystin affects the expression of CXCL1 mRNA
Sterigmatocystin results in increased expression of CXCL1 protein		 CTD PMID:21356202 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression ISO Sterigmatocystin results in increased expression of CXCL9 mRNA CTD PMID:19818335 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 increases expression ISO Sterigmatocystin results in increased expression of CXCR3 mRNA CTD PMID:19818335 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969 		JBrowse link
G Cxcr5 C-X-C motif chemokine receptor 5 increases expression ISO Sterigmatocystin results in increased expression of CXCR5 mRNA CTD PMID:19818335 NCBI chr 8:44,842,098...44,858,425
Ensembl chr 8:44,843,413...44,857,893 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO [CYP1A1 protein results in increased glutathionylation of and results in increased hydroxylation of Sterigmatocystin] which results in increased chemical synthesis of Sterigmatocystin metabolite; CYP1A1 protein results in increased glutathionylation of and results in increased hydroxylation of Sterigmatocystin CTD PMID:20929267 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO [CYP1A2 protein results in increased glutathionylation of and results in increased hydroxylation of Sterigmatocystin] which results in increased chemical synthesis of Sterigmatocystin metabolite; CYP1A2 protein results in increased glutathionylation of and results in increased hydroxylation of Sterigmatocystin CTD PMID:20929267 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects metabolic processing
multiple interactions
increases glutathionylation		 ISO CYP3A4 protein affects the metabolism of Sterigmatocystin
[CYP3A4 protein results in increased glutathionylation of and results in increased hydroxylation of Sterigmatocystin] which results in increased chemical synthesis of Sterigmatocystin metabolite
CYP3A4 protein results in increased glutathionylation of Sterigmatocystin		 CTD PMID:2271712 PMID:2655891 PMID:20929267 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 decreases expression EXP Sterigmatocystin results in decreased expression of DPYSL3 mRNA CTD PMID:34126181 NCBI chr18:35,374,427...35,480,228
Ensembl chr18:35,377,181...35,480,157 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit increases expression EXP Sterigmatocystin results in increased expression of ERCC1 mRNA CTD PMID:34126181 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression EXP Sterigmatocystin results in decreased expression of FOS mRNA CTD PMID:34126181 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Gfap glial fibrillary acidic protein decreases expression EXP Sterigmatocystin results in decreased expression of GFAP mRNA CTD PMID:34126181 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression EXP Sterigmatocystin results in decreased expression of GPX1 mRNA CTD PMID:34126181 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 increases expression EXP Sterigmatocystin results in increased expression of GRIA1 mRNA CTD PMID:34126181 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 increases expression EXP Sterigmatocystin results in increased expression of GRIA2 mRNA CTD PMID:34126181 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 increases expression EXP Sterigmatocystin results in increased expression of GRIA3 mRNA CTD PMID:34126181 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A increases expression EXP Sterigmatocystin results in increased expression of GRIN2A mRNA CTD PMID:34126181 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B increases expression EXP Sterigmatocystin results in increased expression of GRIN2B mRNA CTD PMID:34126181 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D decreases expression EXP Sterigmatocystin results in decreased expression of GRIN2D mRNA CTD PMID:34126181 NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 multiple interactions EXP GSTT1 protein affects the metabolism of and results in decreased activity of Sterigmatocystin metabolite CTD PMID:8951341 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G H2ax H2A.X variant histone increases expression ISO Sterigmatocystin results in increased expression of H2AX protein modified form CTD PMID:26914363 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Hmox1 heme oxygenase 1 decreases expression EXP Sterigmatocystin results in decreased expression of HMOX1 mRNA CTD PMID:34126181 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Ifng interferon gamma increases expression ISO Sterigmatocystin results in increased expression of IFNG mRNA CTD PMID:19818335 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il10 interleukin 10 increases expression ISO
EXP		 Sterigmatocystin results in increased expression of IL10 mRNA CTD PMID:19818335 PMID:34126181 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il10rb interleukin 10 receptor subunit beta increases expression ISO Sterigmatocystin results in increased expression of IL10RB mRNA CTD PMID:19818335 NCBI chr11:30,646,494...30,668,081
Ensembl chr11:30,652,096...30,668,074 		JBrowse link
G Il11 interleukin 11 increases expression ISO Sterigmatocystin results in increased expression of IL11 mRNA CTD PMID:19818335 NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129 		JBrowse link
G Il13 interleukin 13 increases expression ISO Sterigmatocystin results in increased expression of IL13 mRNA CTD PMID:19818335 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il15 interleukin 15 increases expression ISO Sterigmatocystin results in increased expression of IL15 mRNA CTD PMID:19818335 NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820 		JBrowse link
G Il16 interleukin 16 increases expression ISO Sterigmatocystin results in increased expression of IL16 mRNA CTD PMID:19818335 NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130 		JBrowse link
G Il17b interleukin 17B increases expression ISO Sterigmatocystin results in increased expression of IL17B mRNA CTD PMID:19818335 NCBI chr18:55,141,194...55,145,565
Ensembl chr18:55,141,194...55,145,565 		JBrowse link
G Il18 interleukin 18 increases expression ISO Sterigmatocystin results in increased expression of IL18 mRNA CTD PMID:19818335 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO Sterigmatocystin results in increased expression of IL1B mRNA CTD PMID:21356202 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 increases expression ISO Sterigmatocystin results in increased expression of IL1R1 mRNA CTD PMID:19818335 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937 		JBrowse link
G Il2rb interleukin 2 receptor subunit beta increases expression ISO Sterigmatocystin results in increased expression of IL2RB mRNA CTD PMID:19818335 NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054 		JBrowse link
G Il2rg interleukin 2 receptor subunit gamma increases expression ISO Sterigmatocystin results in increased expression of IL2RG mRNA CTD PMID:19818335 NCBI chr  X:66,395,330...66,399,026
Ensembl chr  X:66,392,542...66,399,823 		JBrowse link
G Il3 interleukin 3 increases expression ISO Sterigmatocystin results in increased expression of IL3 mRNA CTD PMID:19818335 NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066 		JBrowse link
G Il36a interleukin 36, alpha increases expression ISO Sterigmatocystin results in increased expression of IL36A mRNA CTD PMID:19818335 NCBI chr 3:6,996,851...7,001,400
Ensembl chr 3:6,996,851...7,001,400 		JBrowse link
G Il5ra interleukin 5 receptor subunit alpha increases expression ISO Sterigmatocystin results in increased expression of IL5RA mRNA CTD PMID:19818335 NCBI chr 4:139,630,652...139,664,593
Ensembl chr 4:139,632,066...139,668,544 		JBrowse link
G Il6 interleukin 6 decreases expression EXP Sterigmatocystin results in decreased expression of IL6 mRNA CTD PMID:34126181 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer decreases expression ISO Sterigmatocystin results in decreased expression of IL6ST mRNA CTD PMID:19818335 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Itgam integrin subunit alpha M increases expression ISO Sterigmatocystin results in increased expression of ITGAM mRNA CTD PMID:19818335 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 affects expression EXP Sterigmatocystin affects the expression of KEAP1 mRNA CTD PMID:34126181 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Lta lymphotoxin alpha increases expression ISO Sterigmatocystin results in increased expression of LTA mRNA CTD PMID:19818335 NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859 		JBrowse link
G Mif macrophage migration inhibitory factor increases expression ISO Sterigmatocystin results in increased expression of MIF mRNA CTD PMID:19818335 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
G Mlh1 mutL homolog 1 multiple interactions
increases expression
affects response to substance		 ISO MLH1 protein affects the reaction [Sterigmatocystin results in increased expression of CCNB1 protein]; MLH1 protein affects the reaction [Sterigmatocystin results in increased expression of CDC25C protein modified form]; MLH1 protein affects the reaction [Sterigmatocystin results in increased expression of CDC25C protein]; MLH1 protein affects the reaction [Sterigmatocystin results in increased expression of CDK1 protein modified form]; MLH1 protein affects the reaction [Sterigmatocystin results in increased expression of CDK1 protein]
Sterigmatocystin results in increased expression of MLH1 mRNA; Sterigmatocystin results in increased expression of MLH1 protein
MLH1 protein affects the susceptibility to Sterigmatocystin		 CTD PMID:23296099 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Msh2 mutS homolog 2 increases expression ISO Sterigmatocystin results in increased expression of MSH2 mRNA; Sterigmatocystin results in increased expression of MSH2 protein CTD PMID:23296099 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases expression EXP Sterigmatocystin results in decreased expression of NFE2L2 mRNA CTD PMID:34126181 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases expression EXP Sterigmatocystin results in decreased expression of NFKB1 mRNA CTD PMID:34126181 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression ISO
EXP		 Sterigmatocystin results in increased expression of NOS2 mRNA CTD PMID:21356202 PMID:34126181 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 decreases expression EXP Sterigmatocystin results in decreased expression of NTRK2 mRNA CTD PMID:34126181 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase increases expression EXP Sterigmatocystin results in increased expression of OGG1 mRNA CTD PMID:34126181 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766 		JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression EXP Sterigmatocystin results in decreased expression of PCNA mRNA CTD PMID:34126181 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pf4 platelet factor 4 increases expression ISO Sterigmatocystin results in increased expression of PF4 mRNA CTD PMID:19818335 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression EXP Sterigmatocystin results in increased expression of PTGS2 mRNA CTD PMID:34126181 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rbfox3 RNA binding fox-1 homolog 3 increases expression EXP Sterigmatocystin results in increased expression of RBFOX3 mRNA CTD PMID:34126181 NCBI chr10:103,720,355...104,157,277
Ensembl chr10:103,720,636...104,156,935 		JBrowse link
G Reln reelin increases expression EXP Sterigmatocystin results in increased expression of RELN mRNA CTD PMID:34126181 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
G Slc17a6 solute carrier family 17 member 6 decreases expression EXP Sterigmatocystin results in decreased expression of SLC17A6 mRNA CTD PMID:34126181 NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542 		JBrowse link
G Slc17a7 solute carrier family 17 member 7 increases expression EXP Sterigmatocystin results in increased expression of SLC17A7 mRNA CTD PMID:34126181 NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588 		JBrowse link
G Sod1 superoxide dismutase 1 decreases expression EXP Sterigmatocystin results in decreased expression of SOD1 mRNA CTD PMID:34126181 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 decreases expression EXP Sterigmatocystin results in decreased expression of SOD2 mRNA CTD PMID:34126181 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sox2 SRY-box transcription factor 2 decreases expression EXP Sterigmatocystin results in decreased expression of SOX2 mRNA CTD PMID:34126181 NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO Sterigmatocystin results in increased expression of SPP1 mRNA CTD PMID:19818335 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Sst somatostatin increases expression EXP Sterigmatocystin results in increased expression of SST mRNA CTD PMID:34126181 NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression EXP Sterigmatocystin results in increased expression of TGFB1 mRNA CTD PMID:34126181 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO Sterigmatocystin results in increased expression of TNF mRNA; Sterigmatocystin results in increased expression of TNF protein CTD PMID:19818335 PMID:21356202 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases expression ISO Sterigmatocystin results in increased expression of TNFRSF1A mRNA CTD PMID:19818335 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tp53 tumor protein p53 increases expression EXP Sterigmatocystin results in increased expression of TP53 mRNA CTD PMID:34126181 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tubb3 tubulin, beta 3 class III decreases expression EXP Sterigmatocystin results in decreased expression of TUBB3 mRNA CTD PMID:34126181 NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243 		JBrowse link
G Xcr1 X-C motif chemokine receptor 1 increases expression ISO Sterigmatocystin results in increased expression of XCR1 mRNA CTD PMID:19818335 NCBI chr 8:123,479,454...123,516,168
Ensembl chr 8:123,479,590...123,487,226 		JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor increases expression ISO Sterigmatocystin results in increased expression of XPC mRNA CTD PMID:23296099 NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    role 19818
      biological role 19785
        poison 18589
          toxin 15966
            mycotoxin 12009
              sterigmatocystins 119
                (3S,7R)-11-[(2R,3R,4R,5S)-3,4-dihydroxy-5-methoxyoxan-2-yl]oxy-15-hydroxy-6,8,20-trioxapentacyclo[10.8.0.02,9.03,7.014,19]icosa-1,4,9,11,14,16,18-heptaen-13-one 0
                (3S,7R)-11-hydroxy-15-methoxy-6,8,20-trioxapentacyclo[10.8.0.02,9.03,7.014,19]icosa-1(12),2(9),10,14(19),15,17-hexaen-13-one 0
                (3S,7R)-11-hydroxy-15-methoxy-6,8,20-trioxapentacyclo[10.8.0.02,9.03,7.014,19]icosa-1(12),2(9),4,10,14(19),15,17-heptaen-13-one 0
                (3S,7R)-15,18-dihydroxy-11-methoxy-6,8,20-trioxapentacyclo[10.8.0.02,9.03,7.014,19]icosa-1,4,9,11,14,16,18-heptaen-13-one 0
                11-hydroxy-O-methyldihydrosterigmatocystin 0
                11-hydroxy-O-methylsterigmatocystin 0
                12,16-dimethoxy-5,7,9,21-tetraoxahexacyclo[11.8.0.0?,??.0?,?.0?,?.0??,??]henicosa-1(13),2(10),11,15,17,19-hexaen-14-one 0
                3,4,5-trihydroxy-6-(\{15-hydroxy-13-oxo-6,8,20-trioxapentacyclo[10.8.0.02,9.03,7.014,19]icosa-1,4,9,11,14,16,18-heptaen-11-yl\}oxy)oxane-2-carboxylic acid 0
                5,6-Dimethoxysterigmatocystin 0
                5-methoxydihydrosterigmatocystin 0
                5-methoxysterigmatocystin 0
                6-demethylsterigmatocystin 0
                8-O-methyldihydrosterigmatocystin 0
                8-O-methylsterigmatocystin 0
                Acyl-hemiacetal sterigmatocystin 0
                Aspertenol B 0
                Aspertenol C 0
                De-O-methyldihydrosterigmatocystin 0
                De-O-methylsterigmatocystin 0
                Dihydro-O-Methylsterigmatocystin 0
                Dihydrohydroxy-O-methylsterigmatocystin 0
                Dihydromethylsterigmatocystin 0
                Hydroxydihydrosterigmatocystin 0
                Oxisterigmatocystin A 0
                Oxisterigmatocystin B 0
                Oxisterigmatocystin C 0
                Oxisterigmatocystin D 0
                Oxisterigmatocystin I 0
                Sterigmatocystin B 0
                Sterigmatocystin C 0
                dihydrodemethylsterigmatocystin + 119
                dihydrosterigmatocystin + 0
                sterigmatocystin + 119
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    p-block element atom 19759
                      carbon group element atom 19708
                        carbon atom 19734
                          organic molecular entity 19705
                            organic molecule 19658
                              organic cyclic compound 19471
                                organic heterocyclic compound 18862
                                  organic heteropolycyclic compound 18301
                                    organic heteropentacyclic compound 13498
                                      sterigmatocystins 119
                                        (3S,7R)-11-[(2R,3R,4R,5S)-3,4-dihydroxy-5-methoxyoxan-2-yl]oxy-15-hydroxy-6,8,20-trioxapentacyclo[10.8.0.02,9.03,7.014,19]icosa-1,4,9,11,14,16,18-heptaen-13-one 0
                                        (3S,7R)-11-hydroxy-15-methoxy-6,8,20-trioxapentacyclo[10.8.0.02,9.03,7.014,19]icosa-1(12),2(9),10,14(19),15,17-hexaen-13-one 0
                                        (3S,7R)-11-hydroxy-15-methoxy-6,8,20-trioxapentacyclo[10.8.0.02,9.03,7.014,19]icosa-1(12),2(9),4,10,14(19),15,17-heptaen-13-one 0
                                        (3S,7R)-15,18-dihydroxy-11-methoxy-6,8,20-trioxapentacyclo[10.8.0.02,9.03,7.014,19]icosa-1,4,9,11,14,16,18-heptaen-13-one 0
                                        11-hydroxy-O-methyldihydrosterigmatocystin 0
                                        11-hydroxy-O-methylsterigmatocystin 0
                                        12,16-dimethoxy-5,7,9,21-tetraoxahexacyclo[11.8.0.0?,??.0?,?.0?,?.0??,??]henicosa-1(13),2(10),11,15,17,19-hexaen-14-one 0
                                        3,4,5-trihydroxy-6-(\{15-hydroxy-13-oxo-6,8,20-trioxapentacyclo[10.8.0.02,9.03,7.014,19]icosa-1,4,9,11,14,16,18-heptaen-11-yl\}oxy)oxane-2-carboxylic acid 0
                                        5,6-Dimethoxysterigmatocystin 0
                                        5-methoxydihydrosterigmatocystin 0
                                        5-methoxysterigmatocystin 0
                                        6-demethylsterigmatocystin 0
                                        8-O-methyldihydrosterigmatocystin 0
                                        8-O-methylsterigmatocystin 0
                                        Acyl-hemiacetal sterigmatocystin 0
                                        Aspertenol B 0
                                        Aspertenol C 0
                                        De-O-methyldihydrosterigmatocystin 0
                                        De-O-methylsterigmatocystin 0
                                        Dihydro-O-Methylsterigmatocystin 0
                                        Dihydrohydroxy-O-methylsterigmatocystin 0
                                        Dihydromethylsterigmatocystin 0
                                        Hydroxydihydrosterigmatocystin 0
                                        Oxisterigmatocystin A 0
                                        Oxisterigmatocystin B 0
                                        Oxisterigmatocystin C 0
                                        Oxisterigmatocystin D 0
                                        Oxisterigmatocystin I 0
                                        Sterigmatocystin B 0
                                        Sterigmatocystin C 0
                                        dihydrodemethylsterigmatocystin + 119
                                        dihydrosterigmatocystin + 0
                                        sterigmatocystin + 119
paths to the root