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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:substituted spermine
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Accession:CHEBI:26735 term browser browse the term


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N(1),N(12)-diethylspermine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat1 spermidine/spermine N1-acetyl transferase 1 multiple interactions
increases expression
ISO [N(1), N(12)-diethylspermine co-treated with Fluorouracil] results in increased activity of SAT1 protein; [N(1), N(12)-diethylspermine co-treated with stallimycin] results in increased activity of SAT1 protein; stallimycin promotes the reaction [N(1), N(12)-diethylspermine results in increased expression of SAT1 protein] CTD PMID:21814787 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19792
      chemical role 19309
        antioxidant 14234
          spermine 66
            substituted spermine 1
              DOSPA trifluoroacetate 0
              N(1),N(12)-diethylspermine 1
              acetylspermine + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19732
                    main group molecular entity 19732
                      s-block molecular entity 19481
                        hydrogen molecular entity 19473
                          hydrides 18745
                            inorganic hydride 17483
                              pnictogen hydride 17456
                                nitrogen hydride 17300
                                  azane 17016
                                    ammonia 17015
                                      organic amino compound 17014
                                        polyamine 8224
                                          tetramine 185
                                            spermine 66
                                              substituted spermine 1
                                                DOSPA trifluoroacetate 0
                                                N(1),N(12)-diethylspermine 1
                                                acetylspermine + 0
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