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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:solanesol
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Accession:CHEBI:26718 term browser browse the term
Definition:A nonaprenol that is hexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-ol substituted by 9 methyl groups at positions 3, 7, 11, 15, 19, 23, 27, 31 and 35 (the all-trans0stereoisomer).
Synonyms:exact_synonym: (2E,6E,10E,14E,18E,22E,26E,30E)-3,7,11,15,19,23,27,31,35-nonamethylhexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-ol
 related_synonym: Formula=C45H74O;   InChI=1S/C45H74O/c1-37(2)19-11-20-38(3)21-12-22-39(4)23-13-24-40(5)25-14-26-41(6)27-15-28-42(7)29-16-30-43(8)31-17-32-44(9)33-18-34-45(10)35-36-46/h19,21,23,25,27,29,31,33,35,46H,11-18,20,22,24,26,28,30,32,34,36H2,1-10H3/b38-21+,39-23+,40-25+,41-27+,42-29+,43-31+,44-33+,45-35+;   InChIKey=AFPLNGZPBSKHHQ-MEGGAXOGSA-N;   SMILES=CC(C)=CCC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CO
 xref: CAS:13190-97-1
 xref_mesh: MESH:C017719
 xref: Reaxys:1717721



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solanesol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO 2-phenylacetylenesulfonamide inhibits the reaction [solanesol inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]]; solanesol inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]; solanesol promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]]; tin protoporphyrin IX inhibits the reaction [solanesol inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]] CTD PMID:25645596 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase multiple interactions ISO solanesol inhibits the reaction [Glucose results in decreased activity of CAT protein] CTD PMID:37586544 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cul3 cullin 3 multiple interactions ISO solanesol inhibits the reaction [KEAP1 protein binds to CUL3 protein binds to RBX1 protein] CTD PMID:25645596 NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO solanesol inhibits the reaction [Glucose results in increased secretion of GPT protein] CTD PMID:37586544 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO geldanamycin inhibits the reaction [solanesol results in increased expression of HMOX1 mRNA]; geldanamycin inhibits the reaction [solanesol results in increased expression of HMOX1 protein]; solanesol inhibits the reaction [Glucose results in decreased expression of HMOX1 mRNA]; solanesol inhibits the reaction [Glucose results in decreased expression of HMOX1 protein]
solanesol results in increased expression of HMOX1 mRNA; solanesol results in increased expression of HMOX1 protein
CTD PMID:25645596 PMID:37586544 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hsf1 heat shock transcription factor 1 multiple interactions
affects localization
ISO 2-phenylacetylenesulfonamide inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; geldanamycin inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; N2-(1H-indazole-5-yl)-N6-methyl-3-nitropyridine-2,6-diamine inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]
solanesol affects the localization of HSF1 protein
CTD PMID:25645596 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions ISO solanesol inhibits the reaction [Glucose results in increased expression of KEAP1 mRNA]; solanesol inhibits the reaction [Glucose results in increased expression of KEAP1 protein]; solanesol inhibits the reaction [KEAP1 protein binds to CUL3 protein binds to RBX1 protein]; solanesol inhibits the reaction [KEAP1 protein binds to NFE2L2 protein] CTD PMID:25645596 PMID:37586544 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO solanesol affects the localization of and results in increased activity of NFE2L2 protein; solanesol inhibits the reaction [Glucose results in decreased expression of NFE2L2 mRNA]; solanesol inhibits the reaction [Glucose results in decreased expression of NFE2L2 protein]; solanesol inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]; solanesol results in decreased ubiquitination of and results in decreased degradation of NFE2L2 protein CTD PMID:25645596 PMID:37586544 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO solanesol inhibits the reaction [Glucose results in decreased expression of NQO1 mRNA]; solanesol inhibits the reaction [Glucose results in decreased expression of NQO1 protein] CTD PMID:37586544 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Rbx1 ring-box 1 multiple interactions ISO solanesol inhibits the reaction [KEAP1 protein binds to CUL3 protein binds to RBX1 protein] CTD PMID:25645596 NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051
JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 multiple interactions ISO 2-phenylacetylenesulfonamide inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; geldanamycin inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; N2-(1H-indazole-5-yl)-N6-methyl-3-nitropyridine-2,6-diamine inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; solanesol promotes the reaction [HSF1 protein binds to STUB1 protein] CTD PMID:25645596 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046
JBrowse link

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  CHEBI ontology 19918
    role 19894
      biological role 19892
        biochemical role 19588
          metabolite 19574
            eukaryotic metabolite 19387
              plant metabolite 17985
                solanesol 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      chalcogen 19612
                        oxygen atom 19586
                          oxygen molecular entity 19586
                            hydroxides 19389
                              organic hydroxy compound 19003
                                alcohol 15559
                                  prenols 527
                                    polyprenol 518
                                      nonaprenol 11
                                        solanesol 11
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