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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:solanesol
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Accession:CHEBI:26718 term browser browse the term
Definition:A nonaprenol that is hexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-ol substituted by 9 methyl groups at positions 3, 7, 11, 15, 19, 23, 27, 31 and 35 (the all-trans0stereoisomer).
Synonyms:exact_synonym: (2E,6E,10E,14E,18E,22E,26E,30E)-3,7,11,15,19,23,27,31,35-nonamethylhexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-ol
 related_synonym: Formula=C45H74O;   InChI=1S/C45H74O/c1-37(2)19-11-20-38(3)21-12-22-39(4)23-13-24-40(5)25-14-26-41(6)27-15-28-42(7)29-16-30-43(8)31-17-32-44(9)33-18-34-45(10)35-36-46/h19,21,23,25,27,29,31,33,35,46H,11-18,20,22,24,26,28,30,32,34,36H2,1-10H3/b38-21+,39-23+,40-25+,41-27+,42-29+,43-31+,44-33+,45-35+;   InChIKey=AFPLNGZPBSKHHQ-MEGGAXOGSA-N;   SMILES=CC(C)=CCC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CO
 xref: CAS:13190-97-1
 xref_mesh: MESH:C017719
 xref: Reaxys:1717721


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solanesol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO 2-phenylacetylenesulfonamide inhibits the reaction [solanesol inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]]; solanesol inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]; solanesol promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]]; tin protoporphyrin IX inhibits the reaction [solanesol inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]] CTD PMID:25645596 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cul3 cullin 3 multiple interactions ISO solanesol inhibits the reaction [KEAP1 protein binds to CUL3 protein binds to RBX1 protein] CTD PMID:25645596 NCBI chr 9:86,044,485...86,129,066
Ensembl chr 9:86,044,485...86,129,329
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO geldanamycin inhibits the reaction [solanesol results in increased expression of HMOX1 mRNA]; geldanamycin inhibits the reaction [solanesol results in increased expression of HMOX1 protein]
solanesol results in increased expression of HMOX1 mRNA; solanesol results in increased expression of HMOX1 protein
CTD PMID:25645596 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsf1 heat shock transcription factor 1 multiple interactions
affects localization
ISO 2-phenylacetylenesulfonamide inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; geldanamycin inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; N2-(1H-indazole-5-yl)-N6-methyl-3-nitropyridine-2,6-diamine inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]
solanesol affects the localization of HSF1 protein
CTD PMID:25645596 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions ISO solanesol inhibits the reaction [KEAP1 protein binds to CUL3 protein binds to RBX1 protein]; solanesol inhibits the reaction [KEAP1 protein binds to NFE2L2 protein] CTD PMID:25645596 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions ISO solanesol affects the localization of and results in increased activity of NFE2L2 protein; solanesol inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]; solanesol results in decreased ubiquitination of and results in decreased degradation of NFE2L2 protein CTD PMID:25645596 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Rbx1 ring-box 1 multiple interactions ISO solanesol inhibits the reaction [KEAP1 protein binds to CUL3 protein binds to RBX1 protein] CTD PMID:25645596 NCBI chr 7:122,700,849...122,710,907
Ensembl chr 7:122,700,854...122,709,935
JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 multiple interactions ISO 2-phenylacetylenesulfonamide inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; geldanamycin inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; N2-(1H-indazole-5-yl)-N6-methyl-3-nitropyridine-2,6-diamine inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; solanesol promotes the reaction [HSF1 protein binds to STUB1 protein] CTD PMID:25645596 NCBI chr10:15,197,754...15,200,035
Ensembl chr10:15,197,803...15,200,117
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        biochemical role 19282
          metabolite 19263
            eukaryotic metabolite 18908
              plant metabolite 17360
                solanesol 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      chalcogen 19362
                        oxygen atom 19323
                          oxygen molecular entity 19323
                            hydroxides 19068
                              organic hydroxy compound 18634
                                alcohol 14987
                                  prenols 514
                                    polyprenol 505
                                      nonaprenol 8
                                        solanesol 8
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