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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:sodium hydrogensulfite
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Accession:CHEBI:26709 term browser browse the term
Definition:An inorganic sodium salt having hydrogensulfite as the counterion.
Synonyms:related_synonym: Formula=HNaO3S;   InChI=1S/Na.H2O3S/c;1-4(2)3/h;(H2,1,2,3)/q+1;/p-1;   InChIKey=DWAQJAXMDSEUJJ-UHFFFAOYSA-M;   NaHSO3;   Natriumbisulfit;   Natriumhydrogensulfit;   SMILES=[Na+].OS([O-])=O;   primaeres Natriumsulfit;   saures Natriumsulfit;   sodium bisulfite;   sodium bisulphite;   sodium hydrogen sulfite
 xref: AGR:IND605265115;   CAS:7631-90-5;   Gmelin:22395
 xref_mesh: MESH:C009279
 xref: PMID:27905861;   PMID:30429859;   PMID:32714086;   PMID:32785935

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sodium hydrogensulfite term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions EXP 6-isopropoxy-9-oxoxanthene-2-carboxylic acid inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; [sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein; Ascorbic Acid inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; Dizocilpine Maleate inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; KT 5720 inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; PTGS2 protein affects the susceptibility to [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; Vitamin E inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein] CTD PMID:21873648 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 decreases expression EXP sodium bisulfite results in decreased expression of COX4 mRNA CTD PMID:26980303 NCBI chr19:54,245,958...54,252,198
Ensembl chr19:54,245,950...54,252,225 		JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 decreases expression EXP sodium bisulfite results in decreased expression of ATP6 mRNA CTD PMID:26980303 NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599 		JBrowse link
G Mt-atp8 mitochondrially encoded ATP synthase membrane subunit 8 multiple interactions
decreases expression		 EXP Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of ATP8 mRNA] CTD PMID:26980303 NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961 		JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I multiple interactions
decreases expression		 EXP Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of COX1 mRNA] CTD PMID:26980303 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867 		JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II decreases expression EXP sodium bisulfite results in decreased expression of COX2 mRNA CTD PMID:26980303 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689 		JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III multiple interactions
decreases expression		 EXP TFAM protein inhibits the reaction [sodium bisulfite results in decreased expression of COX3 mRNA] CTD PMID:26980303 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO sodium bisulfite inhibits the reaction [Rotenone results in increased expression of NOS2 mRNA] CTD PMID:25086357 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
G Nrf1 nuclear respiratory factor 1 multiple interactions
decreases expression		 EXP Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of NRF1 mRNA]
sodium bisulfite results in decreased expression of NRF1 mRNA; sodium bisulfite results in decreased expression of NRF1 protein		 CTD PMID:26980303 NCBI chr 4:57,335,732...57,445,317
Ensembl chr 4:57,378,069...57,445,341 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions
decreases expression		 EXP Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of PPARGC1A mRNA]
sodium bisulfite results in decreased expression of PPARGC1A mRNA; sodium bisulfite results in decreased expression of PPARGC1A protein		 CTD PMID:26980303 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009 		JBrowse link
G Ptger2 prostaglandin E receptor 2 multiple interactions EXP [sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGER2 protein CTD PMID:21873648 NCBI chr15:19,336,029...19,349,759
Ensembl chr15:19,338,175...19,350,210 		JBrowse link
G Ptger4 prostaglandin E receptor 4 multiple interactions EXP [sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGER4 protein CTD PMID:21873648 NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448 		JBrowse link
G Ptges prostaglandin E synthase multiple interactions EXP [sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGES mRNA CTD PMID:21873648 NCBI chr 3:9,727,408...9,738,752
Ensembl chr 3:9,727,408...9,738,752 		JBrowse link
G Ptges2 prostaglandin E synthase 2 multiple interactions EXP [sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGES2 mRNA CTD PMID:21873648 NCBI chr 3:11,424,195...11,431,379
Ensembl chr 3:11,424,099...11,431,402 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions EXP [SC 560 results in decreased activity of PTGS1 protein] promotes the reaction [[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased abundance of Dinoprostone]] CTD PMID:21873648 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP
ISO		 [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased abundance of Cyclic AMP]; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased abundance of Dinoprostone]; [SC 560 results in decreased activity of PTGS1 protein] promotes the reaction [[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased abundance of Dinoprostone]]; [sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGS2 protein; Ascorbic Acid inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGS2 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGS2 protein]; PTGS2 protein affects the susceptibility to [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; Vitamin E inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGS2 protein]
sodium bisulfite inhibits the reaction [Rotenone results in increased expression of PTGS2 mRNA]; sodium bisulfite inhibits the reaction [Rotenone results in increased expression of PTGS2 protein]		 CTD PMID:21873648 PMID:25086357 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Tfam transcription factor A, mitochondrial multiple interactions
decreases expression		 EXP Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of TFAM mRNA]; TFAM protein inhibits the reaction [sodium bisulfite results in decreased expression of COX3 mRNA]
sodium bisulfite results in decreased expression of TFAM mRNA; sodium bisulfite results in decreased expression of TFAM protein		 CTD PMID:26980303 NCBI chr20:18,594,057...18,606,106
Ensembl chr20:18,594,037...18,606,151 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO sodium bisulfite inhibits the reaction [Rotenone results in increased expression of TNF mRNA] CTD PMID:25086357 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19792
      biological role 19792
        aetiopathogenetic role 18974
          allergen 16943
            sodium hydrogensulfite 18
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19732
                    p-block element atom 19732
                      chalcogen 19425
                        oxygen atom 19387
                          oxygen molecular entity 19387
                            hydroxides 19113
                              oxoacid 18243
                                oxoacid derivative 14094
                                  sulfur oxoacid derivative 12278
                                    sulfurous acid derivative 4402
                                      sulfites 4402
                                        sulfite salt 22
                                          sodium hydrogensulfite 18
paths to the root