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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:amlodipine
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Accession:CHEBI:2668 term browser browse the term
Definition:A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
Synonyms:exact_synonym: 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
 related_synonym: 3-Ethyl-5-methyl (+-)-2-(2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate;   Amlodipine Free Base;   Formula=C20H25ClN2O5;   InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3;   InChIKey=HTIQEAQVCYTUBX-UHFFFAOYSA-N;   SMILES=CCOC(=O)C1=C(COCCN)NC(C)=C(C1c1ccccc1Cl)C(=O)OC;   amlodipino;   amlodipinum
 xref: Beilstein:3570229;   CAS:88150-42-9;   DrugBank:DB00381;   Drug_Central:183;   KEGG:C06825;   KEGG:D07450;   LINCS:LSM-1388
 xref_mesh: MESH:D017311
 xref: PMID:1532771;   PMID:16422032;   PMID:1834846;   PMID:19450066;   PMID:21591999;   PMID:7522286;   PMID:8310972;   PMID:8310973;   PMID:9156957;   Patent:EP89167;   Patent:US4572909;   Reaxys:3570229;   VSDB:2963;   Wikipedia:Amlodipine


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Path 1
Term Annotations click to browse term
  CHEBI ontology 0
    role 0
      application 0
        fuel 0
          methanol 0
            methyl ester 0
              amlodipine 0
                (R)-amlodipine 0
                (S)-amlodipine 0
                amlodipine benzenesulfonate + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 0
    subatomic particle 0
      composite particle 0
        hadron 0
          baryon 0
            nucleon 0
              atomic nucleus 0
                atom 0
                  main group element atom 0
                    p-block element atom 0
                      chalcogen 0
                        oxygen atom 0
                          oxygen molecular entity 0
                            hydroxides 0
                              organic hydroxy compound 0
                                alcohol 0
                                  primary alcohol 0
                                    ethanols 0
                                      ethanol 0
                                        ethyl ester 0
                                          amlodipine 0
                                            (R)-amlodipine 0
                                            (S)-amlodipine 0
                                            amlodipine benzenesulfonate + 0
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