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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:sesterterpenoid
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Accession:CHEBI:26660 term browser browse the term
Definition:Any terpenoid derived from a sesterterpene. The term includes compounds in which the C25 skeleton of the parent sesterterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups). Sometimes sesterterpenoids are erroneously referred to as sesterpenoids.
Synonyms:related_synonym: C25 terpenoid;   C25 terpenoids;   sesterpenoids;   sesterterpenoids
 alt_id: CHEBI:53180
 xref: LIPID_MAPS_class:LMPR0105


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manoalide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta multiple interactions ISO manoalide inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein] CTD PMID:7575673 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO manoalide inhibits the reaction [[Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; manoalide inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein] CTD PMID:7575673 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO manoalide inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:7575673 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
ophiobolin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO ophiobolin A inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin] CTD PMID:16904803 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
Scalaradial term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta multiple interactions ISO scalaradial inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; scalaradial inhibits the reaction [IL1B protein results in increased expression of TNF protein]; scalaradial inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein] CTD PMID:7575673 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO scalaradial inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein] CTD PMID:8113982 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO scalaradial inhibits the reaction [[Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; scalaradial inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; scalaradial inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein] CTD PMID:7575673 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO scalaradial inhibits the reaction [IL1B protein results in increased expression of TNF protein]; scalaradial inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:7575673 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
taraxerone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh1 alcohol dehydrogenase 1 (class I) multiple interactions ISO taraxerone promotes the reaction [Ethanol results in increased expression of ADH1 mRNA] CTD PMID:22554647 NCBI chr 2:243,550,655...243,562,243
Ensembl chr 2:243,550,627...243,687,857
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions ISO taraxerone promotes the reaction [Ethanol results in increased expression of ALDH2 mRNA] CTD PMID:22554647 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Cat catalase multiple interactions ISO taraxerone inhibits the reaction [Ethanol results in decreased expression of CAT protein] CTD PMID:22554647 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19786
    chemical entity 19786
      atom 19784
        nonmetal atom 19666
          carbon atom 19586
            organic molecular entity 19586
              isoprenoid 12719
                terpenoid 12288
                  sesterterpenoid 8
                    (17E)-cheilanthenediol 0
                    (3R)-farnesyl-6-hydroxy-2,3,5-trimethyl-4-oxocyclohexa-1,5-diene-1-carboxylic acid 0
                    2-((2E,7E)-3,7-dimethyl-9-((1S,4aS,8aS)-2,5,5,8a-tetramethyl-1,4,4a,5,6,7,8,8a-octahydronaphthalen-1-yl)nona-2,7-dienyl)benzene-1,4-diol 0
                    24,25-Diacetylvulgaroside 0
                    24-Acetyl- 25-cinnamoylvulgaroside 0
                    25-Acetylvulgaroside 0
                    25-Cinnamoyl-vulgaroside 0
                    5,8-Epoxy-5,8-dihydro-10'-apo-b,y-carotene-3,10'-diol 0
                    Antibiotic X 14889A 0
                    Antibiotic X 14889C 0
                    Antibiotic X 14889D 0
                    Azafrin 0
                    Hydroxyphthioceranic acid (C45) 0
                    Perovskone B 0
                    Phthioceranic acid (C43) 0
                    Variecolin 0
                    aplysinoplide A 0
                    aplysinoplide B 0
                    aplysinoplide C 0
                    apo carotenoid C25 terpenoid + 0
                    asperterpenoid A(1-) 0
                    asperterpenoid B(2-) 0
                    asperterpenoid C(1-) 0
                    coscinoquinol, (rel)- 0
                    geranylfarnesol + 0
                    leucosesterlactone 0
                    leucosesterterpenone 0
                    mangicol A 0
                    manoalide 3
                    muqubilone 0
                    ophiobolin A 1
                    ophiobolin C 0
                    ophiobolin F 0
                    preasperterpenoid A 0
                    preluffariellolide A 0
                    scalarane sesterterpenoid + 7
                    sesterfisherol 0
                    stellatic acid 0
                    terretonin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19786
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19675
                    main group molecular entity 19675
                      s-block molecular entity 19443
                        hydrogen molecular entity 19439
                          hydrides 18763
                            organic hydride 18363
                              organic fundamental parent 18363
                                hydrocarbon 18078
                                  terpene 12719
                                    sesterterpene 18
                                      sesterterpenoid 8
                                        (17E)-cheilanthenediol 0
                                        (3R)-farnesyl-6-hydroxy-2,3,5-trimethyl-4-oxocyclohexa-1,5-diene-1-carboxylic acid 0
                                        2-((2E,7E)-3,7-dimethyl-9-((1S,4aS,8aS)-2,5,5,8a-tetramethyl-1,4,4a,5,6,7,8,8a-octahydronaphthalen-1-yl)nona-2,7-dienyl)benzene-1,4-diol 0
                                        24,25-Diacetylvulgaroside 0
                                        24-Acetyl- 25-cinnamoylvulgaroside 0
                                        25-Acetylvulgaroside 0
                                        25-Cinnamoyl-vulgaroside 0
                                        5,8-Epoxy-5,8-dihydro-10'-apo-b,y-carotene-3,10'-diol 0
                                        Antibiotic X 14889A 0
                                        Antibiotic X 14889C 0
                                        Antibiotic X 14889D 0
                                        Azafrin 0
                                        Hydroxyphthioceranic acid (C45) 0
                                        Perovskone B 0
                                        Phthioceranic acid (C43) 0
                                        Variecolin 0
                                        aplysinoplide A 0
                                        aplysinoplide B 0
                                        aplysinoplide C 0
                                        apo carotenoid C25 terpenoid + 0
                                        asperterpenoid A(1-) 0
                                        asperterpenoid B(2-) 0
                                        asperterpenoid C(1-) 0
                                        coscinoquinol, (rel)- 0
                                        geranylfarnesol + 0
                                        leucosesterlactone 0
                                        leucosesterterpenone 0
                                        mangicol A 0
                                        manoalide 3
                                        muqubilone 0
                                        ophiobolin A 1
                                        ophiobolin C 0
                                        ophiobolin F 0
                                        preasperterpenoid A 0
                                        preluffariellolide A 0
                                        scalarane sesterterpenoid + 7
                                        sesterfisherol 0
                                        stellatic acid 0
                                        terretonin 0
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