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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:serine derivative
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Accession:CHEBI:26649 term browser browse the term
Definition:An amino acid derivative resulting from reaction of serine at the amino group or the carboxy group, or from the replacement of any hydrogen of serine by a heteroatom. The definition normally excludes peptides containing serine residues.
Synonyms:related_synonym: serine derivatives



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D-cycloserine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO Cycloserine inhibits the reaction [resveratrol results in increased expression of DDIT3 protein] CTD PMID:24264887 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Egr1 early growth response 1 increases expression EXP Cycloserine results in increased expression of EGR1 protein CTD PMID:19144966 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Cycloserine promotes the reaction [Clozapine results in increased expression of FOS mRNA] CTD PMID:12464447 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Homer1 homer scaffold protein 1 multiple interactions EXP Cycloserine inhibits the reaction [Clozapine results in increased expression of HOMER1 mRNA]; Cycloserine inhibits the reaction [Haloperidol results in increased expression of HOMER1 mRNA] CTD PMID:12464447 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP Cycloserine inhibits the reaction [Dronabinol results in increased activity of MAPK1 protein] CTD PMID:11903061 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP Cycloserine inhibits the reaction [Dronabinol results in increased activity of MAPK3 protein] CTD PMID:11903061 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO Cycloserine inhibits the reaction [resveratrol results in increased cleavage of PARP1 protein] CTD PMID:24264887 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19823
    role 19773
      application 19486
        fuel 11019
          methanol 3865
            hydroxymethyl group 47
              serine 47
                serine derivative 7
                  4-amino-1,2-oxazolidin-3-one + 7
                  D-serine derivative + 0
                  L-serine derivative + 0
                  Mytilin A 0
                  N-(1-deoxy-1-fructosyl)serine 0
                  N-(2,3-dihydroxybenzoyl)serine 0
                  N-(2,4-dinitrophenyl)serine 0
                  N-Methylserine 0
                  N-acylserine + 0
                  N-seryl-glycosylsphingolipidinositolethanolamine 0
                  O-phosphoserine + 0
                  alpha-(hydroxymethyl)serine 0
                  glycerophosphoserine + 0
                  lombricine + 0
                  peptidyl-serine 0
                  serine hydroxamate 0
                  serine phosphoethanolamine + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19823
    subatomic particle 19821
      composite particle 19821
        hadron 19821
          baryon 19821
            nucleon 19821
              atomic nucleus 19821
                atom 19821
                  main group element atom 19720
                    p-block element atom 19720
                      carbon group element atom 19643
                        carbon atom 19633
                          organic molecular entity 19633
                            organic group 18739
                              organic divalent group 18730
                                organodiyl group 18730
                                  carbonyl group 18678
                                    carbonyl compound 18678
                                      carboxylic acid 18376
                                        amino acid 14885
                                          polar amino acid 10731
                                            serine 47
                                              serine derivative 7
                                                4-amino-1,2-oxazolidin-3-one + 7
                                                D-serine derivative + 0
                                                L-serine derivative + 0
                                                Mytilin A 0
                                                N-(1-deoxy-1-fructosyl)serine 0
                                                N-(2,3-dihydroxybenzoyl)serine 0
                                                N-(2,4-dinitrophenyl)serine 0
                                                N-Methylserine 0
                                                N-acylserine + 0
                                                N-seryl-glycosylsphingolipidinositolethanolamine 0
                                                O-phosphoserine + 0
                                                alpha-(hydroxymethyl)serine 0
                                                glycerophosphoserine + 0
                                                lombricine + 0
                                                peptidyl-serine 0
                                                serine hydroxamate 0
                                                serine phosphoethanolamine + 0
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