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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:aldehydic acid
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Accession:CHEBI:26643 term browser browse the term
Definition:A monocarboxylic acid derived from any dicarboxylic acid that has a retained name by the formal reduction of one of the carboxy groups to a formyl group. The resulting structure, also known as a semialdehyde, may be named by replacing the ending '...ic acid' of the retained name of the dicarboxylic acid by the ending '...aldehydic acid'. Aldehydic acids therefore contain one carboxy group and one aldehyde group.
Synonyms:related_synonym: Semialdehyd;   aldehydic acids;   semi-aldehyde;   semi-aldehydes;   semialdehyde;   semialdehydes
 cyclic_relationship: is_conjugate_acid_of CHEBI:71944


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9-oxononanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha decreases activity EXP 9-oxononanoic acid results in decreased activity of ACACA protein CTD PMID:2892534 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
glyoxylic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase decreases activity EXP glyoxylic acid results in decreased activity of G6PD protein CTD PMID:15144222 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Ins2 insulin 2 multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in decreased abundance of glyoxylic acid analog CTD PMID:26820058 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions
increases expression
EXP [glyoxylic acid co-treated with Calcitriol] results in increased expression of SPP1 mRNA
glyoxylic acid results in increased expression of SPP1 protein
CTD PMID:7571189, PMID:8325891 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
phenylglyoxylic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO CYP2E1 polymorphism affects the metabolism of [mandelic acid co-treated with phenylglyoxylic acid] CTD PMID:25562543 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Ephx1 epoxide hydrolase 1 multiple interactions ISO EPHX1 polymorphism affects the metabolism of [mandelic acid co-treated with phenylglyoxylic acid] CTD PMID:25562543 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
succinic semialdehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 increases reduction ISO AKR1A1 protein results in increased reduction of succinic semialdehyde CTD PMID:10510318, PMID:21276435 NCBI chr 5:135,482,068...135,498,693
Ensembl chr 5:135,482,068...135,498,822
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 increases reduction
affects reduction
ISO AKR7A2 protein results in increased reduction of succinic semialdehyde
succinic semialdehyde affects the reduction of AKR7A5 protein
CTD PMID:10510318, PMID:12604212 NCBI chr 5:157,759,448...157,768,473
Ensembl chr 5:157,759,416...157,768,471
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 affects metabolic processing EXP AKR7A3 protein affects the metabolism of succinic semialdehyde CTD PMID:15019089 NCBI chr 5:157,801,120...157,813,756
Ensembl chr 5:157,801,163...157,813,756
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 increases metabolic processing EXP ALDH5A1 protein results in increased metabolism of succinic semialdehyde CTD PMID:17010440, PMID:18926807 NCBI chr17:42,133,076...42,159,413
Ensembl chr17:42,133,076...42,159,413
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      application 19393
        solvent 16459
          formic acid 7881
            formyl group 7847
              aldehyde 7847
                aldehydic acid 10
                  (R)-3-hydroxy-4-oxobutanoic acid 0
                  (S)-methylmalonaldehydic acid 0
                  10-oxocapric acid 0
                  12-oxododecanoic acid 0
                  16-oxohexadecanoic acid 0
                  2-formylbenzoic acid 0
                  22-oxodocosanoic acid 0
                  26-oxohexacosanoic acid 0
                  3-oxopropanoic acid + 0
                  5-formyl-2-furoic acid 0
                  5-oxopentanoic acid + 0
                  6-oxohexanoic acid 0
                  9-oxononanoic acid + 1
                  L-aspartic 4-semialdehyde 0
                  adipate semialdehyde + 0
                  glutamic semialdehyde + 0
                  glyoxylic acid + 5
                  muconate semialdehyde + 0
                  muconic semialdehyde + 0
                  succinate semialdehyde + 0
                  succinic semialdehyde + 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      carboxylic acid 18061
                                        carboacyl group 17348
                                          univalent carboacyl group 17348
                                            formyl group 7847
                                              aldehyde 7847
                                                aldehydic acid 10
                                                  (R)-3-hydroxy-4-oxobutanoic acid 0
                                                  (S)-methylmalonaldehydic acid 0
                                                  10-oxocapric acid 0
                                                  12-oxododecanoic acid 0
                                                  16-oxohexadecanoic acid 0
                                                  2-formylbenzoic acid 0
                                                  22-oxodocosanoic acid 0
                                                  26-oxohexacosanoic acid 0
                                                  3-oxopropanoic acid + 0
                                                  5-formyl-2-furoic acid 0
                                                  5-oxopentanoic acid + 0
                                                  6-oxohexanoic acid 0
                                                  9-oxononanoic acid + 1
                                                  L-aspartic 4-semialdehyde 0
                                                  adipate semialdehyde + 0
                                                  glutamic semialdehyde + 0
                                                  glyoxylic acid + 5
                                                  muconate semialdehyde + 0
                                                  muconic semialdehyde + 0
                                                  succinate semialdehyde + 0
                                                  succinic semialdehyde + 4
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