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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:1,3,5-triazines
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Accession:CHEBI:26588 term browser browse the term
Definition:Any compound with a 1,3,5-triazine skeleton, in which nitrogen atoms replace carbon at positions 1, 3 and 5 of the core benzene ring structure.
Synonyms:related_synonym: s-triazines


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Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDH2 cadherin 2 decreases expression EXP melamine results in decreased expression of CDH2 protein CTD PMID:30055240 NCBI chr 6:112,396,713...112,629,073
Ensembl chr 6:112,396,721...112,628,432 		JBrowse link
G GJA1 gap junction protein alpha 1 decreases expression EXP melamine results in decreased expression of GJA1 protein CTD PMID:30055240 NCBI chr 1:40,988,818...41,002,129
Ensembl chr 1:40,988,515...41,002,137 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 increases phosphorylation EXP melamine results in increased phosphorylation of MAPK1 protein CTD PMID:30055240 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,523 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 increases phosphorylation EXP melamine results in increased phosphorylation of MAPK3 protein CTD PMID:30055240 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567 		JBrowse link
G OCLN occludin decreases expression EXP melamine results in decreased expression of OCLN protein CTD PMID:30055240 NCBI chr16:47,600,175...47,652,435
Ensembl chr16:47,600,498...47,654,033 		JBrowse link
G TJP1 tight junction protein 1 decreases expression EXP melamine results in decreased expression of TJP1 protein CTD PMID:30055240 NCBI chr 1:144,930,387...145,195,857
Ensembl chr 1:144,930,368...145,195,836 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 1018
    chemical entity 1018
      atom 1003
        nonmetal atom 944
          nitrogen atom 447
            nitrogen molecular entity 447
              organonitrogen compound 329
                organonitrogen heterocyclic compound 226
                  triazines 6
                    1,3,5-triazines 6
                      1,3,5-Triazin-2(1H)-one, 4,6-bis((1-methylethyl)amino)- 0
                      1,3,5-triazine + 0
                      2,4,6-tri-4-pyridyl-1,3,5-triazine 0
                      2,4,6-tris(hydroxyamino)-1,3,5-triazine 0
                      2-(dichloromethyl)-4-(ethylthio)-6-phenyl-1,3,5-triazine 0
                      3-[[4,6-bis(4-morpholinyl)-1,3,5-triazin-2-yl]amino]-3-(2-chlorophenyl)propanoic acid ethyl ester 0
                      4,4'-bis(\{4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl\}amino)stilbene-2,2'-disulfonic acid 0
                      5-azaorotic acid 0
                      Aziprotryne 0
                      Desmetryn 0
                      Dimethametryn 0
                      Dipropetryn 0
                      Hexazinone 0
                      Ipazine 0
                      Methoprotryne 0
                      N-glycosyl-1,3,5-triazine + 0
                      N2-tert-butyl-N6-ethyl-N4-propan-2-yl-1,3,5-triazine-2,4,6-triamine 0
                      Trietazine 0
                      chloro-1,3,5-triazine + 0
                      cyanuric acid 0
                      diamino-1,3,5-triazine + 0
                      dihydroxy-1,3,5-triazine + 0
                      enasidenib 0
                      methoxy-1,3,5-triazine + 0
                      methylthio-1,3,5-triazine + 0
                      metsulfuron methyl 0
                      monoamino-1,3,5-triazine + 0
                      monohydroxy-1,3,5-triazine + 0
                      n-cyclopropylammeline 0
                      nitro-1,3,5-triazine + 0
                      thifensulfuron + 0
                      thifensulfuron-methyl 0
                      tretamine 0
                      triamino-1,3,5-triazine + 6
                      triasulfuron 0
                      triflusulfuron + 0
                      triflusulfuron-methyl 0
                      tritosulfuron 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 1018
    subatomic particle 1003
      composite particle 1003
        hadron 1003
          baryon 1003
            nucleon 1003
              atomic nucleus 1003
                atom 1003
                  main group element atom 953
                    p-block element atom 950
                      carbon group element atom 834
                        carbon atom 833
                          organic molecular entity 833
                            organic molecule 752
                              organic cyclic compound 660
                                organic heterocyclic compound 375
                                  heteroarene 99
                                    azaarene 7
                                      triazines 6
                                        1,3,5-triazines 6
                                          1,3,5-Triazin-2(1H)-one, 4,6-bis((1-methylethyl)amino)- 0
                                          1,3,5-triazine + 0
                                          2,4,6-tri-4-pyridyl-1,3,5-triazine 0
                                          2,4,6-tris(hydroxyamino)-1,3,5-triazine 0
                                          2-(dichloromethyl)-4-(ethylthio)-6-phenyl-1,3,5-triazine 0
                                          3-[[4,6-bis(4-morpholinyl)-1,3,5-triazin-2-yl]amino]-3-(2-chlorophenyl)propanoic acid ethyl ester 0
                                          4,4'-bis(\{4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl\}amino)stilbene-2,2'-disulfonic acid 0
                                          5-azaorotic acid 0
                                          Aziprotryne 0
                                          Desmetryn 0
                                          Dimethametryn 0
                                          Dipropetryn 0
                                          Hexazinone 0
                                          Ipazine 0
                                          Methoprotryne 0
                                          N-glycosyl-1,3,5-triazine + 0
                                          N2-tert-butyl-N6-ethyl-N4-propan-2-yl-1,3,5-triazine-2,4,6-triamine 0
                                          Trietazine 0
                                          chloro-1,3,5-triazine + 0
                                          cyanuric acid 0
                                          diamino-1,3,5-triazine + 0
                                          dihydroxy-1,3,5-triazine + 0
                                          enasidenib 0
                                          methoxy-1,3,5-triazine + 0
                                          methylthio-1,3,5-triazine + 0
                                          metsulfuron methyl 0
                                          monoamino-1,3,5-triazine + 0
                                          monohydroxy-1,3,5-triazine + 0
                                          n-cyclopropylammeline 0
                                          nitro-1,3,5-triazine + 0
                                          thifensulfuron + 0
                                          thifensulfuron-methyl 0
                                          tretamine 0
                                          triamino-1,3,5-triazine + 6
                                          triasulfuron 0
                                          triflusulfuron + 0
                                          triflusulfuron-methyl 0
                                          tritosulfuron 0
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