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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:ribose phosphate
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Accession:CHEBI:26562 term browser browse the term
Synonyms:related_synonym: ribose phosphates


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3',5'-cyclic AMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 increases expression
multiple interactions		 ISO Cyclic AMP results in increased expression of ABCA1 mRNA; Cyclic AMP results in increased expression of ABCA1 protein
[HCAR2 protein results in decreased abundance of Cyclic AMP] which results in decreased expression of ABCA1 protein		 CTD PMID:20339114 PMID:20655299 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155 		JBrowse link
G ABCC4 ATP binding cassette subfamily C member 4 (PEL blood group) increases transport
multiple interactions
affects uptake		 EXP
ISO		 ABCC4 protein results in increased transport of Cyclic AMP
Probenecid affects the reaction [ABCC4 protein affects the uptake of Cyclic AMP analog]		 CTD PMID:11856762 PMID:28587784 NCBI chr13:95,019,835...95,301,451
Ensembl chr13:95,019,835...95,301,475 		JBrowse link
G ADCYAP1 adenylate cyclase activating polypeptide 1 multiple interactions EXP [ADCYAP1 protein binds to VIPR2 protein] which results in increased abundance of Cyclic AMP CTD PMID:7733904 NCBI chr18:904,411...912,172
Ensembl chr18:904,871...912,172 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing increases abundance EXP ADIPOQ protein results in increased abundance of Cyclic AMP CTD PMID:18931039 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G ADM adrenomedullin multiple interactions
increases abundance		 ISO ADM protein inhibits the reaction [Isoproterenol promotes the reaction [ADM protein results in increased abundance of Cyclic AMP]]; CALCA protein inhibits the reaction [Isoproterenol promotes the reaction [ADM protein results in increased abundance of Cyclic AMP]]; Isoproterenol promotes the reaction [ADM protein results in increased abundance of Cyclic AMP]
ADM protein results in increased abundance of Cyclic AMP; ADM results in increased abundance of Cyclic AMP		 CTD PMID:10374718 PMID:17306419 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397 		JBrowse link
G ADRA1B adrenoceptor alpha 1B multiple interactions ISO ADRA1B protein affects the reaction [Isoproterenol results in increased abundance of Cyclic AMP] CTD PMID:12649302 NCBI chr 5:159,865,086...159,989,205
Ensembl chr 5:159,865,080...159,973,012 		JBrowse link
G ADRB1 adrenoceptor beta 1 multiple interactions
increases abundance
affects abundance		 EXP
ISO		 [3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [Acebutolol co-treated with ADRB1] results in increased abundance of Cyclic AMP; [ADRB1 protein binds to ADRB2 protein] which results in increased abundance of Cyclic AMP; [Alprenolol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [Atenolol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [Atenolol co-treated with ADRB1] results in increased abundance of Cyclic AMP; [Bisoprolol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [Bupranolol co-treated with ADRB1] results in increased abundance of Cyclic AMP; [carvedilol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [carvedilol co-treated with ADRB1] results in increased abundance of Cyclic AMP; [CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP; [CGP 12177 binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [CGP 12177 co-treated with ADRB1] results in increased abundance of Cyclic AMP; [CGP 20712A binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] promotes the reaction [[ADRB1 protein binds to ADRB2 protein] which results in increased abundance of Cyclic AMP]; [Epinephrine binds to and results in increased activity of ADRB1 protein] which results in increased abundance of Cyclic AMP; [Fenoterol binds to and results in increased activity of ADRB1 protein] which results in increased abundance of Cyclic AMP; [Formoterol Fumarate binds to and results in increased activity of ADRB1 protein] which results in increased abundance of Cyclic AMP; [ICI 118551 binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [Isoproterenol binds to and results in increased activity of ADRB1 protein] which results in increased abundance of Cyclic AMP; [Labetalol co-treated with ADRB1] results in increased abundance of Cyclic AMP; [Metoprolol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [Norepinephrine binds to and results in increased activity of ADRB1 protein] which results in increased abundance of Cyclic AMP; [Pindolol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [Propranolol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [Propranolol co-treated with ADRB1] results in increased abundance of Cyclic AMP; [Salmeterol Xinafoate binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; ADRB1 protein polymorphism affects the reaction [[carvedilol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP]; Alprenolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Atenolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Bisoprolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Bupranolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; carvedilol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; CGP 20712A inhibits the reaction [[Acebutolol co-treated with ADRB1] results in increased abundance of Cyclic AMP]; CGP 20712A inhibits the reaction [[carvedilol co-treated with ADRB1] results in increased abundance of Cyclic AMP]; CGP 20712A inhibits the reaction [[CGP 12177 co-treated with ADRB1] results in increased abundance of Cyclic AMP]; CGP 20712A inhibits the reaction [[Labetalol co-treated with ADRB1] results in increased abundance of Cyclic AMP]; Isoproterenol promotes the reaction [ADRB1 protein results in increased abundance of Cyclic AMP]; Metoprolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Nadolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Oxprenolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Pindolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Sotalol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Timolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]
ADRB1 protein affects the abundance of Cyclic AMP; ADRB1 protein polymorphism affects the abundance of Cyclic AMP
ADRB1 protein promotes the reaction [Isoproterenol results in increased abundance of Cyclic AMP]		 CTD PMID:11562432 PMID:12761341 PMID:14502278 PMID:14730417 PMID:15060759 More... NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904 		JBrowse link
G ADRB2 adrenoceptor beta 2 multiple interactions
increases chemical synthesis
increases abundance
affects abundance		 ISO
EXP		 [Terbutaline results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; ADRB2 protein promotes the reaction [Isoproterenol results in increased abundance of Cyclic AMP]
ADRB2 protein polymorphism results in increased chemical synthesis of Cyclic AMP; ADRB2 protein results in increased chemical synthesis of Cyclic AMP
[Acebutolol binds to ADRB2 protein] which results in increased abundance of Cyclic AMP; [ADRB1 protein binds to ADRB2 protein] which results in increased abundance of Cyclic AMP; [Albuterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [Alprenolol binds to ADRB2 protein] which results in increased abundance of Cyclic AMP; [Atenolol binds to ADRB2 protein] which results in increased abundance of Cyclic AMP; [Atenolol binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Betaxolol binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Bisoprolol binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Bisoprolol binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; [BRL 37344 binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; [broxaterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [carvedilol binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP; [carvedilol binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; [CGP 12177 binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; [CGP 20712A binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] promotes the reaction [[ADRB1 protein binds to ADRB2 protein] which results in increased abundance of Cyclic AMP]; [Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [Fenoterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [Formoterol Fumarate binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [ICI 118551 binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP; [ICI 118551 binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [Isoproterenol results in increased activity of ADRB2 protein] which results in increased chemical synthesis of Cyclic AMP; [Labetalol binds to ADRB2 protein] which results in increased abundance of Cyclic AMP; [Metaproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [Metoprolol binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Metoprolol binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Nadolol binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Norepinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [Oxprenolol binds to ADRB2 protein] which results in increased abundance of Cyclic AMP; [Pindolol binds to ADRB2 protein] which results in increased abundance of Cyclic AMP; [Pindolol binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Practolol binds to ADRB2 protein] which results in increased abundance of Cyclic AMP; [Propranolol binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Propranolol binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Salmeterol Xinafoate binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [Sotalol binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [Timolol binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP; Atenolol inhibits the reaction [[Albuterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Atenolol inhibits the reaction [[Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Atenolol inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Atenolol inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; ICI 118551 inhibits the reaction [[Albuterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; ICI 118551 inhibits the reaction [[Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; ICI 118551 inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; ICI 118551 inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [[Albuterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [[Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]
ADRB2 protein results in increased abundance of Cyclic AMP
ADRB2 protein affects the abundance of Cyclic AMP		 CTD PMID:10516654 PMID:10857765 PMID:10952688 PMID:11562432 PMID:12920204 More... NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623 		JBrowse link
G ADRB3 adrenoceptor beta 3 multiple interactions
affects abundance		 EXP 3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [[SR 59119A binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP]; [Albuterol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; [Alprenolol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; [BRL 37344 binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; [broxaterol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; [CGP 12177 binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; [CGP 20712A binds to and results in decreased activity of ADRB3 protein] which results in decreased abundance of Cyclic AMP; [Epinephrine binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; [Fenoterol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; [Formoterol Fumarate binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; [ICI 118551 binds to and results in decreased activity of ADRB3 protein] which results in decreased abundance of Cyclic AMP; [Isoproterenol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; [Norepinephrine binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; [Pindolol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; [Salmeterol Xinafoate binds to and results in decreased activity of ADRB3 protein] which results in decreased abundance of Cyclic AMP; [SR 59119A binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; [Terbutaline binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP
ADRB3 protein affects the abundance of Cyclic AMP		 CTD PMID:10952688 PMID:14730417 NCBI chr 8:37,962,990...37,966,599
Ensembl chr 8:37,962,990...37,966,599 		JBrowse link
G AHCYL1 adenosylhomocysteinase like 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of AHCYL1 mRNA] CTD PMID:19414516 NCBI chr 1:109,984,765...110,023,742
Ensembl chr 1:109,984,765...110,023,742 		JBrowse link
G AHR aryl hydrocarbon receptor multiple interactions
decreases expression		 ISO
EXP		 AHR protein promotes the reaction [Cyclic AMP results in increased expression of CYP1B1 mRNA]; Cyclic AMP inhibits the reaction [AHR protein binds to ARNT protein]; Cyclic AMP promotes the reaction [AHR protein binds to CYP1B1 enhancer]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of AHR mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Kynurenine co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of AHR mRNA]; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of AHR mRNA; [Kynurenine co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of AHR mRNA
Cyclic AMP results in decreased expression of AHR protein		 CTD PMID:12859982 PMID:32781018 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G ALPP alkaline phosphatase, placental multiple interactions EXP [Colforsin results in increased abundance of Cyclic AMP] which results in increased expression of ALPP mRNA CTD PMID:16036225 NCBI chr 2:232,378,751...232,382,889
Ensembl chr 2:232,378,724...232,382,889 		JBrowse link
G ANGPTL4 angiopoietin like 4 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of ANGPTL4 mRNA] CTD PMID:19414516 NCBI chr19:8,364,155...8,374,370
Ensembl chr19:8,363,289...8,374,370 		JBrowse link
G ANK2 ankyrin 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of ANK2 mRNA] CTD PMID:19414516 NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221 		JBrowse link
G AQP3 aquaporin 3 (Gill blood group) multiple interactions
increases expression		 EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Cyclic AMP results in increased expression of AQP3 mRNA]; N-(2-aminoethyl)-5-isoquinolinesulfonamide inhibits the reaction [Cyclic AMP results in increased expression of AQP3 mRNA] CTD PMID:12542607 NCBI chr 9:33,441,160...33,447,593
Ensembl chr 9:33,441,156...33,447,596 		JBrowse link
G AQP5 aquaporin 5 multiple interactions ISO Chloroquine inhibits the reaction [Cyclic AMP results in decreased expression of AQP5 protein]; Cyclic AMP affects the expression of and results in increased phosphorylation of and results in increased localization of AQP5 protein CTD PMID:15536076 NCBI chr12:49,961,872...49,965,682
Ensembl chr12:49,961,872...49,965,682 		JBrowse link
G ARMH4 armadillo like helical domain containing 4 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of ARMH4 mRNA] CTD PMID:19414516 NCBI chr14:58,000,761...58,152,213
Ensembl chr14:57,999,735...58,298,139 		JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator multiple interactions ISO Cyclic AMP inhibits the reaction [AHR protein binds to ARNT protein] CTD PMID:12859982 NCBI chr 1:150,809,713...150,876,599
Ensembl chr 1:150,809,713...150,876,708 		JBrowse link
G ARRB2 arrestin beta 2 multiple interactions EXP [[GCG protein binds to and results in increased activity of GLP1R protein] which results in increased chemical synthesis of Cyclic AMP] promotes the reaction [ARRB2 protein binds to GLP1R protein]; [[GCG protein binds to and results in increased activity of GLP1R protein] which results in increased chemical synthesis of Cyclic AMP] which affects the localization of ARRB2 protein CTD PMID:25191754 NCBI chr17:4,710,632...4,721,497
Ensembl chr17:4,710,596...4,721,499 		JBrowse link
G ATF5 activating transcription factor 5 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of ATF5 mRNA] CTD PMID:19414516 NCBI chr19:49,928,906...49,933,935
Ensembl chr19:49,928,702...49,933,935 		JBrowse link
G AVP arginine vasopressin multiple interactions EXP [AVP protein binds to and results in increased activity of AVPR2 protein mutant form] which results in increased abundance of Cyclic AMP; [AVP protein binds to and results in increased activity of AVPR2 protein] which results in increased abundance of Cyclic AMP CTD PMID:20683494 NCBI chr20:3,082,556...3,084,724
Ensembl chr20:3,082,556...3,084,724 		JBrowse link
G AVPR2 arginine vasopressin receptor 2 multiple interactions
increases abundance		 EXP [AVP protein binds to and results in increased activity of AVPR2 protein mutant form] which results in increased abundance of Cyclic AMP; [AVP protein binds to and results in increased activity of AVPR2 protein] which results in increased abundance of Cyclic AMP
AVPR2 protein results in increased abundance of Cyclic AMP		 CTD PMID:20683494 PMID:33638691 NCBI chr  X:153,902,625...153,907,166
Ensembl chr  X:153,902,531...153,907,166 		JBrowse link
G BDNF brain derived neurotrophic factor multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of E2F2 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of FOXM1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of FZD10 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of GLI1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of HES3 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of HOXB1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of INHBE mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of LEF1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of TERT mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of CNTN1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of DLG4 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GABRA2 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GFAP mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIA2 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN2A mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN2B mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of MAP2 protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of RBFOX3 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of RBFOX3 protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of S100B mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of S100B protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SCN2A mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SLC17A6 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SLC17A7 protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SYN mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SYN protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of TUBB3 protein CTD PMID:33713149 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase increases activity
multiple interactions		 EXP
ISO		 Cyclic AMP results in increased activity of BRAF protein
[Pentoxifylline results in increased abundance of Cyclic AMP] which results in increased activity of BRAF protein; [Theophylline results in increased abundance of Cyclic AMP] which results in increased activity of BRAF protein		 CTD PMID:21693435 NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929 		JBrowse link
G C1orf115 chromosome 1 open reading frame 115 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of C13H1ORF115 mRNA] CTD PMID:19414516 NCBI chr 1:220,690,363...220,699,153
Ensembl chr 1:220,690,363...220,699,153 		JBrowse link
G C1QTNF5 C1q and TNF related 5 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of C1QTNF5 mRNA] CTD PMID:19414516 NCBI chr11:119,338,942...119,346,705
Ensembl chr11:119,338,942...119,340,940 		JBrowse link
G CALCA calcitonin related polypeptide alpha increases abundance
multiple interactions		 EXP
ISO		 CALCA protein modified form results in increased abundance of Cyclic AMP; CALCA protein results in increased abundance of Cyclic AMP
CALCA protein inhibits the reaction [Isoproterenol promotes the reaction [ADM protein results in increased abundance of Cyclic AMP]]
Isoflurane inhibits the reaction [CALCA protein modified form results in increased abundance of Cyclic AMP]; sevoflurane inhibits the reaction [CALCA protein modified form results in increased abundance of Cyclic AMP]		 CTD PMID:15297469 PMID:17295025 PMID:17306419 PMID:18463244 NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354 		JBrowse link
G CARM1 coactivator associated arginine methyltransferase 1 multiple interactions
increases phosphorylation		 EXP [Cyclic AMP results in increased phosphorylation of CARM1 protein] promotes the reaction [CARM1 protein binds to ESR1 protein]; CARM1 protein promotes the reaction [Cyclic AMP results in increased activity of ESR1 protein]; CARM1 protein promotes the reaction [Cyclic AMP results in increased expression of TFF1 mRNA]; Cyclic AMP promotes the reaction [CARM1 protein binds to ESR1 protein]; Cyclic AMP promotes the reaction [CARM1 protein binds to TFF1 promoter] CTD PMID:20360387 NCBI chr19:10,871,553...10,923,075
Ensembl chr19:10,871,553...10,923,075 		JBrowse link
G CCKBR cholecystokinin B receptor multiple interactions ISO CCKBR protein affects the reaction [[quinelorane binds to and results in increased activity of DRD2 protein] which results in decreased abundance of Cyclic AMP] CTD PMID:11880531 NCBI chr11:6,259,838...6,272,127
Ensembl chr11:6,259,806...6,272,127 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 multiple interactions ISO Cyclic AMP inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL3 protein] CTD PMID:9863660 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G CCN2 cellular communication network factor 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of CCN2 mRNA] CTD PMID:19414516 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372 		JBrowse link
G CCND1 cyclin D1 multiple interactions ISO
EXP		 [Theophylline results in increased abundance of Cyclic AMP] which results in increased expression of CCND1 protein; sorafenib inhibits the reaction [[Theophylline results in increased abundance of Cyclic AMP] which results in increased expression of CCND1 protein] CTD PMID:21693435 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CD3E CD3 epsilon subunit of T-cell receptor complex decreases phosphorylation ISO Cyclic AMP results in decreased phosphorylation of CD3E protein CTD PMID:2824607 NCBI chr11:118,304,730...118,316,173
Ensembl chr11:118,304,730...118,316,175 		JBrowse link
G CD3G CD3 gamma subunit of T-cell receptor complex decreases phosphorylation ISO Cyclic AMP results in decreased phosphorylation of CD3G protein CTD PMID:2824607 NCBI chr11:118,344,344...118,355,161
Ensembl chr11:118,344,344...118,355,161 		JBrowse link
G CDC42 cell division cycle 42 multiple interactions
increases chemical synthesis		 ISO [Cholera Toxin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP; [Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP; CRH protein inhibits the reaction [[Cholera Toxin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]; Sphingosine inhibits the reaction [CRH protein inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]]; Sphingosine inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]]; Staurosporine inhibits the reaction [CRH protein inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]]; Tetradecanoylphorbol Acetate inhibits the reaction [[Cholera Toxin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP] CTD PMID:2153673 NCBI chr 1:22,052,709...22,101,360
Ensembl chr 1:22,052,627...22,101,360 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B multiple interactions ISO
EXP		 [Pentoxifylline results in increased abundance of Cyclic AMP] which results in increased expression of CDKN1B protein; [Theophylline results in increased abundance of Cyclic AMP] which results in increased expression of CDKN1B protein; sorafenib inhibits the reaction [[Theophylline results in increased abundance of Cyclic AMP] which results in increased expression of CDKN1B protein] CTD PMID:21693435 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369 		JBrowse link
G CEBPB CCAAT enhancer binding protein beta increases response to substance ISO CEBPB protein results in increased susceptibility to Cyclic AMP CTD PMID:23097472 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668 		JBrowse link
G CFTR CF transmembrane conductance regulator multiple interactions
increases activity		 EXP
ISO		 Cyclic AMP promotes the reaction [CFTR protein results in increased transport of Bicarbonates]; Cyclic AMP promotes the reaction [CFTR protein results in increased transport of Chlorides]
CFTR protein promotes the reaction [Cyclic AMP results in increased transport of Chlorine]; Cyclic AMP affects the localization of and results in increased activity of CFTR protein; Nitric Oxide inhibits the reaction [CFTR protein promotes the reaction [Cyclic AMP results in increased transport of Chlorine]]; Nocodazole inhibits the reaction [Cyclic AMP affects the localization of and results in increased activity of CFTR protein]; Primaquine inhibits the reaction [Cyclic AMP affects the localization of and results in increased activity of CFTR protein]
Cyclic AMP results in increased activity of CFTR protein
Genistein promotes the reaction [Cyclic AMP results in increased activity of CFTR protein mutant form]		 CTD PMID:11786964 PMID:12529251 PMID:12556293 PMID:12612912 PMID:15229107 More... NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971 		JBrowse link
G CGA glycoprotein hormones, alpha polypeptide multiple interactions
affects secretion
increases abundance		 ISO
EXP		 [Flufenamic Acid results in decreased abundance of Cyclic AMP] which results in decreased expression of CGA mRNA
CGA protein affects the secretion of Cyclic AMP
CGA protein results in increased abundance of Cyclic AMP
[CGA protein affects the secretion of Cyclic AMP] which results in increased secretion of Progesterone; [CGA protein co-treated with 1-Methyl-3-isobutylxanthine] results in increased abundance of Cyclic AMP; [CGA protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP; Colforsin promotes the reaction [CGA protein results in increased abundance of Cyclic AMP]; Cyclic AMP inhibits the reaction [[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of PGR mRNA]]; DDT inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]; DDT promotes the reaction [[CGA protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]
[ESR2 gene mutant form results in decreased expression of LHCGR protein] inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]; Colforsin inhibits the reaction [ESR2 gene mutant form inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]]; ESR2 gene mutant form inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]		 CTD PMID:8404651 PMID:20378682 PMID:21642635 PMID:23071612 PMID:26895433 More... NCBI chr 6:87,085,498...87,095,106
Ensembl chr 6:87,085,498...87,095,106 		JBrowse link
G CGB3 chorionic gonadotropin subunit beta 3 multiple interactions
increases abundance
increases secretion		 EXP [CGB3 protein results in increased activity of LHCGR protein] which results in increased abundance of Cyclic AMP; Atrazine inhibits the reaction [CGB3 protein results in increased secretion of Cyclic AMP]; Atrazine promotes the reaction [CGB3 protein results in increased abundance of Cyclic AMP]; Colforsin promotes the reaction [CGB3 protein results in increased abundance of Cyclic AMP]; ESR1 protein promotes the reaction [[CGB3 protein results in increased activity of LHCGR protein] which results in increased abundance of Cyclic AMP]; ESR2 protein promotes the reaction [[CGB3 protein results in increased activity of LHCGR protein] which results in increased abundance of Cyclic AMP]; Estradiol inhibits the reaction [[CGB3 protein results in increased activity of LHCGR protein] which results in increased abundance of Cyclic AMP]; Flame Retardants inhibits the reaction [[CGB3 protein co-treated with Colforsin] results in increased abundance of Cyclic AMP]; Flame Retardants inhibits the reaction [Colforsin promotes the reaction [CGB3 protein results in increased abundance of Cyclic AMP]]; hexabromocyclododecane inhibits the reaction [Colforsin promotes the reaction [CGB3 protein results in increased abundance of Cyclic AMP]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Atrazine promotes the reaction [CGB3 protein results in increased abundance of Cyclic AMP]] CTD PMID:19541795 PMID:19766106 PMID:20667998 PMID:22461451 PMID:23347875 NCBI chr19:49,022,869...49,024,333
Ensembl chr19:49,022,869...49,024,333 		JBrowse link
G CHSY1 chondroitin sulfate synthase 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of CHSY1 mRNA] CTD PMID:19414516 NCBI chr15:101,175,727...101,252,048
Ensembl chr15:101,175,727...101,252,048 		JBrowse link
G CNR1 cannabinoid receptor 1 multiple interactions ISO
EXP		 [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] which results in increased abundance of Cyclic AMP
(1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl)-(2,2,3,3-tetramethylcyclopropyl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; (1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; (4-ethyl-1-naphthalenyl)(1-(5-fluoropentyl)-1H-indol-3-yl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(2-cyclohexylethyl)-3-(2-methoxyphenylacetyl)indole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyfluoro-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyl-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyl-3-(1-naphthoyl)indole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 2-(4-methoxyphenyl)-1-(1-pentyl-indol-3-yl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-((adamantan-1-yl)carbonyl)-1-pentylindole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-((adamantan-1-yl)carbonyl)-1-pentylindole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] which results in increased abundance of Cyclic AMP; [Dronabinol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; AM 6527 analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; AM 6527 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; CNR1 protein inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; Dronabinol inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; FDU-PB-22 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; FUB-PB-22 compound inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Indazoles analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Indoles analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(1-adamantyl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(1-adamantyl)-1-pentylindazole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamtan-1-yl)-1-pentyl-1H-indole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamtan-1-yl)-1-pentyl-1H-indole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; napht-1-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] which results in increased abundance of Cyclic AMP]; THJ-2201 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; XLR-11 analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; XLR-11 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]		 CTD PMID:10422789 PMID:11730719 PMID:17953657 PMID:27429655 NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347 		JBrowse link
G CNR2 cannabinoid receptor 2 multiple interactions EXP (1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl)-(2,2,3,3-tetramethylcyclopropyl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; (1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; (4-ethyl-1-naphthalenyl)(1-(5-fluoropentyl)-1H-indol-3-yl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(2-cyclohexylethyl)-3-(2-methoxyphenylacetyl)indole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyfluoro-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyl-1H-indole-3-carboxylic acid 8-quinolinyl ester inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 1-pentyl-3-(1-naphthoyl)indole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 2-(4-methoxyphenyl)-1-(1-pentyl-indol-3-yl)methanone inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-((adamantan-1-yl)carbonyl)-1-pentylindole analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; 3-((adamantan-1-yl)carbonyl)-1-pentylindole inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [Dronabinol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [virodhamine binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; AM 6527 analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; AM 6527 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; CNR2 protein inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; Dronabinol inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; FDU-PB-22 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; FUB-PB-22 compound inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Indazoles analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Indoles analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(1-adamantyl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(1-adamantyl)-1-pentylindazole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamtan-1-yl)-1-pentyl-1H-indole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-(adamtan-1-yl)-1-pentyl-1H-indole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; napht-1-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; Pertussis Toxin inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; Pertussis Toxin inhibits the reaction [[virodhamine binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; SR 144528 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; SR 144528 inhibits the reaction [[virodhamine binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; THJ-2201 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; XLR-11 analog inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]]; XLR-11 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]] CTD PMID:17558435 PMID:27429655 NCBI chr 1:23,870,515...23,913,362
Ensembl chr 1:23,870,515...23,913,362 		JBrowse link
G CNTN1 contactin 1 multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of CNTN1 mRNA CTD PMID:33713149 NCBI chr12:40,692,439...41,072,415
Ensembl chr12:40,692,439...41,072,415 		JBrowse link
G CP ceruloplasmin multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of CP mRNA] CTD PMID:19414516 NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions ISO [Dexamethasone co-treated with Cyclic AMP] results in increased phosphorylation of CREB1 protein; [Glucagon co-treated with Cyclic AMP] results in increased phosphorylation of CREB1 protein; Cyclic AMP promotes the reaction [CREB1 protein binds to CYP1B1 enhancer] CTD PMID:12859982 PMID:22676303 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988 		JBrowse link
G CREBBP CREB binding protein multiple interactions EXP CREBBP protein promotes the reaction [Cyclic AMP results in increased activity of ESR1 protein] CTD PMID:20360387 NCBI chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713 		JBrowse link
G CRH corticotropin releasing hormone multiple interactions EXP
ISO		 [CRHR1 protein binds to and results in increased activity of CRH protein] which results in increased abundance of Cyclic AMP; Progesterone promotes the reaction [[CRHR1 protein binds to and results in increased activity of CRH protein] which results in increased abundance of Cyclic AMP]
CRH protein inhibits the reaction [[Cholera Toxin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [[LHB protein co-treated with Guanylyl Imidodiphosphate] results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [Cholera Toxin results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [LHB protein results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [Manganese results in increased chemical synthesis of Cyclic AMP]; Sphingosine inhibits the reaction [CRH protein inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]]; Staurosporine inhibits the reaction [CRH protein inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]]		 CTD PMID:2153673 PMID:20702571 NCBI chr 8:66,176,376...66,178,464
Ensembl chr 8:66,176,376...66,178,464 		JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 multiple interactions EXP [CRHR1 protein binds to and results in increased activity of CRH protein] which results in increased abundance of Cyclic AMP; Progesterone promotes the reaction [[CRHR1 protein binds to and results in increased activity of CRH protein] which results in increased abundance of Cyclic AMP] CTD PMID:20702571 NCBI chr17:45,784,320...45,835,828
Ensembl chr17:45,784,277...45,835,828 		JBrowse link
G CRP C-reactive protein multiple interactions ISO Cyclic AMP inhibits the reaction [IL1B protein results in increased expression of CRP mRNA] CTD PMID:22117073 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CSF3 colony stimulating factor 3 increases expression EXP Cyclic AMP results in increased expression of CSF3 protein CTD PMID:7540958 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813 		JBrowse link
G CSK C-terminal Src kinase multiple interactions ISO CSK protein promotes the reaction [Epinephrine results in increased abundance of Cyclic AMP]; CSK protein promotes the reaction [Isoproterenol results in increased abundance of Cyclic AMP]; CSK protein promotes the reaction [Terbutaline results in increased abundance of Cyclic AMP]; Isoproterenol inhibits the reaction [CSK protein promotes the reaction [Epinephrine results in increased abundance of Cyclic AMP]] CTD PMID:1699227 NCBI chr15:74,782,080...74,803,197
Ensembl chr15:74,782,080...74,803,197 		JBrowse link
G CSTB cystatin B multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of CSTB mRNA] CTD PMID:19414516 NCBI chr21:43,773,950...43,776,308
Ensembl chr21:43,772,511...43,776,330 		JBrowse link
G CTSA cathepsin A multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of CTSA mRNA] CTD PMID:19414516 NCBI chr20:45,891,335...45,898,820
Ensembl chr20:45,890,144...45,898,949 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP [Terbutaline results in increased abundance of Cyclic AMP] which results in increased expression of CXCL8 protein CTD PMID:9258252 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 increases expression
multiple interactions		 ISO
EXP		 Cyclic AMP results in increased expression of CYP11A1 mRNA
Cyclic AMP results in increased expression of CYP11A1 mRNA; Cyclic AMP results in increased expression of CYP11A1 protein
myricetin promotes the reaction [Cyclic AMP results in increased expression of CYP11A1 mRNA]; quercetin pentaacetate promotes the reaction [Cyclic AMP results in increased expression of CYP11A1 mRNA]; Quercetin promotes the reaction [Cyclic AMP results in increased expression of CYP11A1 mRNA]		 CTD PMID:25576683 PMID:28668616 PMID:29228121 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646 		JBrowse link
G CYP11B1 cytochrome P450 family 11 subfamily B member 1 increases expression
multiple interactions		 EXP Cyclic AMP results in increased expression of CYP11B1 mRNA
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Cyclic AMP results in increased expression of CYP11B1 mRNA]		 CTD PMID:22172629 NCBI chr 8:142,872,357...142,879,825
Ensembl chr 8:142,872,356...142,879,846 		JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 multiple interactions
increases expression		 EXP
ISO		 [acetyl methyl tetramethyl tetralin co-treated with Cyclic AMP] results in decreased activity of CYP17A1 protein; [acetyl methyl tetramethyl tetralin co-treated with Cyclic AMP] results in increased activity of CYP17A1 protein; [galaxolide co-treated with Cyclic AMP] results in decreased activity of CYP17A1 protein; [galaxolide co-treated with Cyclic AMP] results in increased activity of CYP17A1 protein
Cyclic AMP results in increased expression of CYP17A1 mRNA		 CTD PMID:23084589 PMID:25576683 NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472 		JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 increases expression
multiple interactions		 EXP Cyclic AMP results in increased expression of CYP19A1 mRNA; Cyclic AMP results in increased expression of CYP19A1 protein
[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of CYP19A1 mRNA; Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of CYP19A1 mRNA]; Dronabinol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of CYP19A1 mRNA]		 CTD PMID:29228121 PMID:31953017 NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions EXP 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1A1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Kynurenine co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1A1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Tryptophan co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1A1 mRNA]; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1A1 mRNA; [Kynurenine co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1A1 mRNA; [Tryptophan co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1A1 mRNA CTD PMID:32781018 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 increases expression
multiple interactions		 ISO
EXP		 Cyclic AMP results in increased expression of CYP1B1 mRNA; Cyclic AMP results in increased expression of CYP1B1 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1B1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Kynurenine co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1B1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Tryptophan co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1B1 mRNA]; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1B1 mRNA; [Kynurenine co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1B1 mRNA; [Tryptophan co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1B1 mRNA
AHR protein promotes the reaction [Cyclic AMP results in increased expression of CYP1B1 mRNA]; Cyclic AMP promotes the reaction [AHR protein binds to CYP1B1 enhancer]; Cyclic AMP promotes the reaction [CREB1 protein binds to CYP1B1 enhancer]		 CTD PMID:12859982 PMID:32781018 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G CYP2A6 cytochrome P450 family 2 subfamily A member 6 increases expression
multiple interactions		 ISO Cyclic AMP results in increased expression of CYP2A5 mRNA
Cyclic AMP promotes the reaction [HNF4A protein binds to CYP2A5 promoter]; Cyclic AMP promotes the reaction [PPARGC1A protein binds to CYP2A5 promoter]; Dactinomycin inhibits the reaction [Cyclic AMP results in increased expression of CYP2A5 mRNA]		 CTD PMID:12754101 PMID:18602936 NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447 		JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 increases expression ISO Cyclic AMP results in increased expression of CYP51 mRNA CTD PMID:25576683 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803 		JBrowse link
G CYP7B1 cytochrome P450 family 7 subfamily B member 1 decreases expression
decreases activity		 ISO Cyclic AMP results in decreased expression of CYP7B1 mRNA
Cyclic AMP results in decreased activity of CYP7B1 protein		 CTD PMID:12029625 NCBI chr 8:64,586,575...64,798,737
Ensembl chr 8:64,587,763...64,798,737 		JBrowse link
G DAP death associated protein multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of DAP mRNA] CTD PMID:19414516 NCBI chr 5:10,679,230...10,761,234
Ensembl chr 5:10,679,230...10,761,234 		JBrowse link
G DDT D-dopachrome tautomerase multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of DDT mRNA] CTD PMID:19414516 NCBI chr22:23,971,370...23,980,504
Ensembl chr22:23,970,542...23,980,525 		JBrowse link
G DISC1 DISC1 scaffold protein multiple interactions EXP Cyclic AMP inhibits the reaction [DISC1 protein binds to PDE4B protein] CTD PMID:16293762 NCBI chr 1:231,626,790...232,041,272
Ensembl chr 1:231,626,790...232,041,272 		JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 affects response to substance EXP DKK1 protein affects the susceptibility to Cyclic AMP CTD PMID:21546446 NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042 		JBrowse link
G DLD dihydrolipoamide dehydrogenase increases abundance ISO DLD protein results in increased abundance of Cyclic AMP CTD PMID:25981801 NCBI chr 7:107,891,107...107,921,198
Ensembl chr 7:107,891,162...107,931,730 		JBrowse link
G DLG4 discs large MAGUK scaffold protein 4 multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of DLG4 mRNA CTD PMID:33713149 NCBI chr17:7,187,187...7,220,050
Ensembl chr17:7,187,187...7,219,841 		JBrowse link
G DRD1 dopamine receptor D1 multiple interactions EXP
ISO		 A 86929 promotes the reaction [DRD1 protein results in increased chemical synthesis of Cyclic AMP]
[SK&F 82958 analog results in increased activity of DRD1 protein] which results in increased abundance of Cyclic AMP; A 86929 promotes the reaction [DRD1 protein results in increased chemical synthesis of Cyclic AMP]; SCH 23390 inhibits the reaction [A 86929 promotes the reaction [DRD1 protein results in increased chemical synthesis of Cyclic AMP]]; SCH 23390 inhibits the reaction [Simvastatin promotes the reaction [[SK&F 82958 analog results in increased activity of DRD1 protein] which results in increased abundance of Cyclic AMP]]; Simvastatin promotes the reaction [[SK&F 82958 analog results in increased activity of DRD1 protein] which results in increased abundance of Cyclic AMP]; Spiperone inhibits the reaction [A 86929 promotes the reaction [DRD1 protein results in increased chemical synthesis of Cyclic AMP]]		 CTD PMID:8558425 PMID:15711596 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182 		JBrowse link
G DRD2 dopamine receptor D2 multiple interactions EXP
ISO		 [Quinpirole binds to and results in increased activity of DRD2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; epigallocatechin gallate inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]
[quinelorane binds to and results in increased activity of DRD2 protein] which results in decreased abundance of Cyclic AMP; CCKBR protein affects the reaction [[quinelorane binds to and results in increased activity of DRD2 protein] which results in decreased abundance of Cyclic AMP]		 CTD PMID:11880531 PMID:17958328 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691 		JBrowse link
G DRD4 dopamine receptor D4 multiple interactions ISO [3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-1H-pyrrolo(2,3-b)pyridine binds to and results in decreased activity of DRD4 protein] inhibits the reaction [Naloxone results in increased abundance of Cyclic AMP] CTD PMID:15542745 NCBI chr11:637,269...640,706
Ensembl chr11:637,269...640,706 		JBrowse link
G E2F2 E2F transcription factor 2 multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of E2F2 mRNA CTD PMID:33713149 NCBI chr 1:23,505,212...23,531,233
Ensembl chr 1:23,506,438...23,531,233 		JBrowse link
G EGFR epidermal growth factor receptor multiple interactions ISO [Cimetidine results in decreased abundance of Cyclic AMP] inhibits the reaction [EGFR protein results in increased phosphorylation of EGFR protein] CTD PMID:17295779 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EGR1 early growth response 1 multiple interactions ISO [[Eugenol results in increased activity of OR5D18 protein] which results in increased abundance of Cyclic AMP] which results in increased expression of EGR1 mRNA CTD PMID:12767924 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303 		JBrowse link
G EHD2 EH domain containing 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of EHD2 mRNA] CTD PMID:19414516 NCBI chr19:47,713,422...47,743,134
Ensembl chr19:47,713,422...47,743,134 		JBrowse link
G ENDOD1 endonuclease domain containing 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of ENDOD1 mRNA] CTD PMID:19414516 NCBI chr11:95,089,846...95,132,645
Ensembl chr11:95,089,846...95,132,645 		JBrowse link
G ENO2 enolase 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of ENO2 mRNA] CTD PMID:19414516 NCBI chr12:6,914,580...6,923,697
Ensembl chr12:6,913,745...6,923,698 		JBrowse link
G EPO erythropoietin increases expression ISO Cyclic AMP results in increased expression of EPO protein CTD PMID:18621143 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700 		JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 increases expression ISO Cyclic AMP results in increased expression of ERRFI1 mRNA CTD PMID:1472065 NCBI chr 1:8,011,727...8,026,309
Ensembl chr 1:8,004,404...8,026,309 		JBrowse link
G ESR1 estrogen receptor 1 multiple interactions
increases activity		 EXP [Cyclic AMP results in increased phosphorylation of CARM1 protein] promotes the reaction [CARM1 protein binds to ESR1 protein]; CARM1 protein promotes the reaction [Cyclic AMP results in increased activity of ESR1 protein]; CREBBP protein promotes the reaction [Cyclic AMP results in increased activity of ESR1 protein]; Cyclic AMP promotes the reaction [CARM1 protein binds to ESR1 protein]; ESR1 protein promotes the reaction [[CGB3 protein results in increased activity of LHCGR protein] which results in increased abundance of Cyclic AMP]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Cyclic AMP results in increased activity of ESR1 protein] CTD PMID:19766106 PMID:20360387 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G ESR2 estrogen receptor 2 multiple interactions EXP
ISO		 ESR2 protein promotes the reaction [[CGB3 protein results in increased activity of LHCGR protein] which results in increased abundance of Cyclic AMP]
[ESR2 gene mutant form results in decreased expression of LHCGR protein] inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]; Colforsin inhibits the reaction [ESR2 gene mutant form inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]]; ESR2 gene mutant form inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]		 CTD PMID:19766106 PMID:20378682 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G F2R coagulation factor II thrombin receptor multiple interactions ISO [C186 65 binds to and results in increased activity of F2R protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [C186 65 binds to and results in increased activity of F2R protein] which results in decreased chemical synthesis of Cyclic AMP CTD PMID:22207716 NCBI chr 5:76,716,126...76,735,770
Ensembl chr 5:76,716,126...76,735,770 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 multiple interactions EXP Cyclic AMP promotes the reaction [F2RL1 protein results in increased transport of Chlorides] CTD PMID:11804840 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315 		JBrowse link
G F2RL3 F2R like thrombin or trypsin receptor 3 multiple interactions ISO [GYPGKF-NH(2) binds to and results in increased activity of F2RL3 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [GYPGKF-NH(2) binds to and results in increased activity of F2RL3 protein] which results in decreased chemical synthesis of Cyclic AMP CTD PMID:22207716 NCBI chr19:16,888,999...16,892,606
Ensembl chr19:16,888,999...16,892,606 		JBrowse link
G FAM20C FAM20C golgi associated secretory pathway kinase multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of FAM20C mRNA] CTD PMID:19414516 NCBI chr 7:192,571...260,772
Ensembl chr 7:192,571...260,772 		JBrowse link
G FCGR2A Fc gamma receptor IIa multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of FCGR3 mRNA] CTD PMID:19414516 NCBI chr 1:161,505,457...161,524,048
Ensembl chr 1:161,505,430...161,524,013 		JBrowse link
G FDX1 ferredoxin 1 increases expression
multiple interactions		 ISO Cyclic AMP results in increased expression of FDX1 mRNA
myricetin promotes the reaction [Cyclic AMP results in increased expression of FDX1 mRNA]; quercetin pentaacetate promotes the reaction [Cyclic AMP results in increased expression of FDX1 mRNA]; Quercetin promotes the reaction [Cyclic AMP results in increased expression of FDX1 mRNA]		 CTD PMID:28668616 NCBI chr11:110,429,331...110,464,884
Ensembl chr11:110,429,948...110,464,884 		JBrowse link
G FIG4 FIG4 phosphoinositide 5-phosphatase multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of FIG4 mRNA] CTD PMID:19414516 NCBI chr 6:109,691,296...109,825,426
Ensembl chr 6:109,690,609...109,878,098 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 EXP
ISO		 [Etoposide co-treated with Cyclic AMP] results in increased expression of FOS mRNA
Cyclic AMP results in increased expression of FOS mRNA		 CTD PMID:10064622 PMID:10711420 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G FOXM1 forkhead box M1 multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of FOXM1 mRNA CTD PMID:33713149 NCBI chr12:2,857,680...2,877,174
Ensembl chr12:2,857,680...2,877,174 		JBrowse link
G FOXO1 forkhead box O1 multiple interactions EXP
ISO		 [Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of FOXO1 mRNA; Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of FOXO1 mRNA]
FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]]		 CTD PMID:26847930 PMID:31953017 NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641 		JBrowse link
G FSHB follicle stimulating hormone subunit beta multiple interactions
increases abundance
increases secretion		 ISO
EXP		 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane inhibits the reaction [FSHB protein results in increased abundance of Cyclic AMP]; 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [FSHB protein results in increased abundance of Cyclic AMP]; [Flufenamic Acid results in decreased abundance of Cyclic AMP] which results in decreased expression of FSHB mRNA; fulvestrant inhibits the reaction [FSHB protein results in increased abundance of Cyclic AMP]; Methoxychlor inhibits the reaction [FSHB protein results in increased abundance of Cyclic AMP]; Octreotide inhibits the reaction [FSHB protein results in increased abundance of Cyclic AMP]; pasireotide inhibits the reaction [FSHB protein results in increased abundance of Cyclic AMP]
FSHB protein results in increased secretion of Cyclic AMP
NOG protein inhibits the reaction [Octreotide inhibits the reaction [FSHB protein results in increased abundance of Cyclic AMP]]; NOG protein inhibits the reaction [pasireotide inhibits the reaction [FSHB protein results in increased abundance of Cyclic AMP]]
[FSHB protein co-treated with Testosterone] results in increased chemical synthesis of Cyclic AMP; [FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP; Benzo(a)pyrene inhibits the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]; DDT promotes the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]; Dichlorodiphenyl Dichloroethylene promotes the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]; o,p'-DDT promotes the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]		 CTD PMID:8404651 PMID:18535249 PMID:23137853 PMID:23583632 PMID:25549949 More... NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261 		JBrowse link
G FSHR follicle stimulating hormone receptor multiple interactions EXP [CGA protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP; [FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP; Benzo(a)pyrene inhibits the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]; DDT promotes the reaction [[CGA protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]; DDT promotes the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]; Dichlorodiphenyl Dichloroethylene promotes the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]; o,p'-DDT promotes the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP] CTD PMID:26895433 NCBI chr 2:48,962,157...49,154,515
Ensembl chr 2:48,962,157...49,154,527 		JBrowse link
G FZD10 frizzled class receptor 10 multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of FZD10 mRNA CTD PMID:33713149 NCBI chr12:130,162,464...130,165,740
Ensembl chr12:130,162,459...130,165,740 		JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO [Dexamethasone co-treated with Cyclic AMP] results in increased expression of G6PC1 mRNA; [Glucagon co-treated with Cyclic AMP] results in increased expression of G6PC1 mRNA; Fatty Acids analog inhibits the reaction [[Dexamethasone co-treated with Cyclic AMP] results in increased expression of G6PC1 mRNA]; Fatty Acids analog inhibits the reaction [[Glucagon co-treated with Cyclic AMP] results in increased expression of G6PC1 mRNA]
[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein; [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]; arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]]; INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]		 CTD PMID:22676303 PMID:26847930 NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438 		JBrowse link
G GABPB1 GA binding protein transcription factor subunit beta 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of GABPB1 mRNA] CTD PMID:19414516 NCBI chr15:50,275,389...50,355,198
Ensembl chr15:50,275,389...50,355,408 		JBrowse link
G GABRA2 gamma-aminobutyric acid type A receptor subunit alpha2 multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GABRA2 mRNA CTD PMID:33713149 NCBI chr 4:46,243,548...46,390,300
Ensembl chr 4:46,243,548...46,475,230 		JBrowse link
G GBP2 guanylate binding protein 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of GBP2 mRNA] CTD PMID:19414516 NCBI chr 1:89,106,132...89,126,114
Ensembl chr 1:89,106,132...89,150,456 		JBrowse link
G GCG glucagon multiple interactions
increases chemical synthesis
increases abundance		 ISO
EXP		 [GCG protein modified form binds to and results in increased activity of GLP1R protein] which results in increased abundance of Cyclic AMP
Dietary Fats promotes the reaction [GCG protein results in increased chemical synthesis of Cyclic AMP]; Niclosamide inhibits the reaction [GCG protein results in increased abundance of Cyclic AMP]
[[GCG protein binds to and results in increased activity of GLP1R protein] which results in increased chemical synthesis of Cyclic AMP] promotes the reaction [ARRB2 protein binds to GLP1R protein]; [[GCG protein binds to and results in increased activity of GLP1R protein] which results in increased chemical synthesis of Cyclic AMP] promotes the reaction [GRK2 protein binds to GLP1R protein]; [[GCG protein binds to and results in increased activity of GLP1R protein] which results in increased chemical synthesis of Cyclic AMP] which affects the localization of ARRB2 protein; [GCG protein binds to and results in increased activity of GLP1R protein] which results in increased chemical synthesis of Cyclic AMP		 CTD PMID:6312992 PMID:18669601 PMID:20074626 PMID:25191754 PMID:26964897 NCBI chr 2:162,142,882...162,152,247
Ensembl chr 2:162,142,882...162,152,404 		JBrowse link
G GDNF glial cell derived neurotrophic factor multiple interactions EXP 3,9-bis((ethylthio)methyl)-K-252a inhibits the reaction [[GDNF protein co-treated with Cyclic AMP] results in increased susceptibility to 1-Methyl-4-phenylpyridinium]; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of E2F2 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of FOXM1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of FZD10 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of GLI1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of HES3 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of HOXB1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of INHBE mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of LEF1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of TERT mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of CNTN1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of DLG4 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GABRA2 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GFAP mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIA2 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN2A mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN2B mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of MAP2 protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of RBFOX3 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of RBFOX3 protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of S100B mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of S100B protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SCN2A mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SLC17A6 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SLC17A7 protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SYN mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SYN protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of TUBB3 protein; [GDNF protein co-treated with Cyclic AMP] results in decreased susceptibility to 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; [GDNF protein co-treated with Cyclic AMP] results in increased susceptibility to 1-Methyl-4-phenylpyridinium; Mazindol inhibits the reaction [[GDNF protein co-treated with Cyclic AMP] results in increased susceptibility to 1-Methyl-4-phenylpyridinium]; vanoxerine inhibits the reaction [[GDNF protein co-treated with Cyclic AMP] results in increased susceptibility to 1-Methyl-4-phenylpyridinium] CTD PMID:19647008 PMID:33713149 NCBI chr 5:37,812,677...37,840,041
Ensembl chr 5:37,812,677...37,840,041 		JBrowse link
G GFAP glial fibrillary acidic protein multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GFAP mRNA CTD PMID:33713149 NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937 		JBrowse link
G GHRH growth hormone releasing hormone multiple interactions EXP [GH-RH(1-29), desaminotyrosyl(1)-ornithyl(12,21)-alpha-aminobutryic acid(15)-norleucyl(27)-aspartyl(28)-agmatine(29)- binds to and results in increased activity of GHRH protein] which results in increased abundance of Cyclic AMP CTD PMID:22308467 NCBI chr20:37,251,086...37,261,814
Ensembl chr20:37,251,086...37,261,819 		JBrowse link
G GIP gastric inhibitory polypeptide multiple interactions EXP [GIP protein binds to and results in increased activity of GIPR protein] which results in increased chemical synthesis of Cyclic AMP CTD PMID:25191754 NCBI chr17:48,958,554...48,968,596
Ensembl chr17:48,958,554...48,968,596 		JBrowse link
G GIPR gastric inhibitory polypeptide receptor multiple interactions EXP [GIP protein binds to and results in increased activity of GIPR protein] which results in increased chemical synthesis of Cyclic AMP CTD PMID:25191754 NCBI chr19:45,668,221...45,683,722
Ensembl chr19:45,668,221...45,683,722 		JBrowse link
G GLI1 GLI family zinc finger 1 multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of GLI1 mRNA CTD PMID:33713149 NCBI chr12:57,459,785...57,472,268
Ensembl chr12:57,459,785...57,472,268 		JBrowse link
G GLIPR2 GLI pathogenesis related 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of GLIPR2 mRNA] CTD PMID:19414516 NCBI chr 9:36,136,536...36,163,913
Ensembl chr 9:36,136,536...36,163,913 		JBrowse link
G GLP1R glucagon like peptide 1 receptor multiple interactions ISO
EXP		 [GCG protein modified form binds to and results in increased activity of GLP1R protein] which results in increased abundance of Cyclic AMP
[[GCG protein binds to and results in increased activity of GLP1R protein] which results in increased chemical synthesis of Cyclic AMP] promotes the reaction [ARRB2 protein binds to GLP1R protein]; [[GCG protein binds to and results in increased activity of GLP1R protein] which results in increased chemical synthesis of Cyclic AMP] promotes the reaction [GRK2 protein binds to GLP1R protein]; [[GCG protein binds to and results in increased activity of GLP1R protein] which results in increased chemical synthesis of Cyclic AMP] which affects the localization of ARRB2 protein; [GCG protein binds to and results in increased activity of GLP1R protein] which results in increased chemical synthesis of Cyclic AMP		 CTD PMID:18669601 PMID:25191754 NCBI chr 6:39,048,781...39,091,303
Ensembl chr 6:39,048,781...39,091,303 		JBrowse link
G GNAI2 G protein subunit alpha i2 multiple interactions ISO [[IER3 protein affects the chemical synthesis of Reactive Oxygen Species] which results in increased expression of GNAI2] which results in decreased chemical synthesis of Cyclic AMP CTD PMID:20713914 NCBI chr 3:50,227,068...50,263,358
Ensembl chr 3:50,226,292...50,259,362 		JBrowse link
G GNAL G protein subunit alpha L multiple interactions EXP [[GNAL protein results in increased susceptibility to citronellal] which results in increased activity of OR6E1 protein] which results in increased abundance of Cyclic AMP CTD PMID:15598656 NCBI chr18:11,689,264...11,885,685
Ensembl chr18:11,689,264...11,885,685 		JBrowse link
G GNAS GNAS complex locus multiple interactions EXP
ISO		 [[GNAS protein results in increased susceptibility to citronellal] which results in increased activity of OR6E1 protein] which results in increased abundance of Cyclic AMP; GNAS protein promotes the reaction [[cicaprost results in increased activity of PTGIR protein] which results in increased abundance of Cyclic AMP]
[[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Cyclic AMP; [[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Cyclic AMP		 CTD PMID:11895442 PMID:15598656 PMID:23022524 NCBI chr20:58,839,748...58,911,192
Ensembl chr20:58,839,718...58,911,192 		JBrowse link
G GPBAR1 G protein-coupled bile acid receptor 1 multiple interactions ISO
EXP		 [[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Cyclic AMP; [[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Cyclic AMP
[Chenodeoxycholic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased abundance of Cyclic AMP; [Colforsin binds to and results in increased activity of GPBAR1 protein] which results in increased abundance of Cyclic AMP; [Lithocholic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased abundance of Cyclic AMP		 CTD PMID:17963371 PMID:23022524 NCBI chr 2:218,259,496...218,263,861
Ensembl chr 2:218,259,496...218,263,861 		JBrowse link
G GPC3 glypican 3 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of GPC3 mRNA] CTD PMID:19414516 NCBI chr  X:133,535,745...133,985,594
Ensembl chr  X:133,535,745...133,987,100 		JBrowse link
G GREB1L GREB1 like retinoic acid receptor coactivator multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of GREB1L mRNA] CTD PMID:19414516 NCBI chr18:21,242,232...21,526,112
Ensembl chr18:21,242,232...21,526,112 		JBrowse link
G GRIA2 glutamate ionotropic receptor AMPA type subunit 2 multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIA2 mRNA CTD PMID:33713149 NCBI chr 4:157,220,120...157,366,075
Ensembl chr 4:157,204,182...157,387,146 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN1 mRNA CTD PMID:33713149 NCBI chr 9:137,139,154...137,168,756
Ensembl chr 9:137,138,346...137,168,756 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN2A mRNA CTD PMID:33713149 NCBI chr16:9,753,404...10,182,908
Ensembl chr16:9,753,404...10,182,928 		JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN2B mRNA CTD PMID:33713149 NCBI chr12:13,537,337...13,982,134
Ensembl chr12:13,437,942...13,982,002 		JBrowse link
G GRK2 G protein-coupled receptor kinase 2 multiple interactions EXP [[GCG protein binds to and results in increased activity of GLP1R protein] which results in increased chemical synthesis of Cyclic AMP] promotes the reaction [GRK2 protein binds to GLP1R protein] CTD PMID:25191754 NCBI chr11:67,266,473...67,286,556
Ensembl chr11:67,266,473...67,286,556 		JBrowse link
G GRN granulin precursor multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of GRN mRNA] CTD PMID:19414516 NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta multiple interactions ISO GSK3B protein affects the reaction [Deamino Arginine Vasopressin results in increased abundance of Cyclic AMP] CTD PMID:20056751 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G GTPBP2 GTP binding protein 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of GTPBP2 mRNA] CTD PMID:19414516 NCBI chr 6:43,620,494...43,631,333
Ensembl chr 6:43,605,316...43,629,264 		JBrowse link
G GYPC glycophorin C (Gerbich blood group) multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of GYPC mRNA] CTD PMID:19414516 NCBI chr 2:126,656,158...126,696,667
Ensembl chr 2:126,656,133...126,696,667 		JBrowse link
G H2BC11 H2B clustered histone 11 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of HIST2H2BE mRNA] CTD PMID:19414516 NCBI chr 6:27,132,316...27,132,795
Ensembl chr 6:27,125,897...27,132,795 		JBrowse link
G HCAR2 hydroxycarboxylic acid receptor 2 multiple interactions
decreases abundance		 EXP [3-Hydroxybutyric Acid results in increased activity of HCAR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [Niacin results in increased activity of HCAR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [Nicotinic Acids binds to and results in increased activity of HCAR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; Pertussis Toxin inhibits the reaction [[Nicotinic Acids binds to and results in increased activity of HCAR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]
HCAR2 protein results in decreased abundance of Cyclic AMP		 CTD PMID:17124637 PMID:19223991 PMID:20655299 NCBI chr12:122,701,293...122,703,357
Ensembl chr12:122,701,293...122,703,357 		JBrowse link
G HCAR3 hydroxycarboxylic acid receptor 3 decreases abundance
multiple interactions		 EXP
ISO		 HCAR3 protein results in decreased abundance of Cyclic AMP
HCAR2 protein results in decreased abundance of Cyclic AMP
[HCAR2 protein results in decreased abundance of Cyclic AMP] which results in decreased expression of ABCA1 protein; [Niacin binds to and results in increased activity of HCAR2 protein] which results in decreased abundance of Cyclic AMP		 CTD PMID:12563315 PMID:19237584 PMID:20655299 NCBI chr12:122,714,756...122,716,811
Ensembl chr12:122,714,756...122,716,811 		JBrowse link
G HDAC2 histone deacetylase 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of HDAC2 mRNA] CTD PMID:19414516 NCBI chr 6:113,933,028...113,971,148
Ensembl chr 6:113,933,028...114,011,308 		JBrowse link
G HDAC6 histone deacetylase 6 affects abundance ISO HDAC6 protein affects the abundance of Cyclic AMP CTD PMID:28887310 NCBI chr  X:48,801,398...48,824,982
Ensembl chr  X:48,801,377...48,824,982 		JBrowse link
G HES3 hes family bHLH transcription factor 3 multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of HES3 mRNA CTD PMID:33713149 NCBI chr 1:6,244,179...6,245,578
Ensembl chr 1:6,244,179...6,245,578 		JBrowse link
G HIVEP2 HIVEP zinc finger 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of HIVEP2 mRNA] CTD PMID:19414516 NCBI chr 6:142,751,469...142,946,365
Ensembl chr 6:142,751,469...142,956,698 		JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha multiple interactions ISO Cyclic AMP promotes the reaction [HNF4A protein binds to CYP2A5 promoter] CTD PMID:18602936 NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,699...44,432,845 		JBrowse link
G HOXB1 homeobox B1 multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of HOXB1 mRNA CTD PMID:33713149 NCBI chr17:48,528,526...48,531,011
Ensembl chr17:48,528,526...48,531,011 		JBrowse link
G HP haptoglobin multiple interactions ISO Cyclic AMP inhibits the reaction [IL1B protein results in increased expression of HP mRNA] CTD PMID:22117073 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055 		JBrowse link
G HRH1 histamine receptor H1 multiple interactions EXP 1-Methyl-3-isobutylxanthine inhibits the reaction [HRH1 protein promotes the reaction [Histamine results in decreased abundance of Cyclic AMP]]; HRH1 protein promotes the reaction [Histamine results in decreased abundance of Cyclic AMP]; Triprolidine inhibits the reaction [HRH1 protein promotes the reaction [Histamine results in decreased abundance of Cyclic AMP]] CTD PMID:2419744 NCBI chr 3:11,137,238...11,263,557
Ensembl chr 3:11,137,093...11,263,557 		JBrowse link
G HRH2 histamine receptor H2 increases abundance
multiple interactions		 EXP HRH2 protein results in increased abundance of Cyclic AMP
[Cimetidine binds to and results in decreased activity of HRH2 protein] which results in decreased abundance of Cyclic AMP; [Dimaprit binds to and results in increased activity of HRH2 protein] which results in increased abundance of Cyclic AMP; [Histamine binds to and results in increased activity of HRH2 protein] which results in increased abundance of Cyclic AMP; Burimamide inhibits the reaction [[Cyclic AMP binds to and results in decreased activity of HRH2 protein] which results in decreased abundance of Cimetidine]; Burimamide inhibits the reaction [[Cyclic AMP binds to and results in increased activity of HRH2 protein] which results in increased abundance of Histamine]; Cyclic AMP promotes the reaction [[Histamine results in increased activity of HRH2 protein] which results in decreased expression of IL12A protein]; Cyclic AMP promotes the reaction [[Histamine results in increased activity of HRH2 protein] which results in decreased expression of IL12B protein]; Dimaprit inhibits the reaction [HRH2 protein promotes the reaction [Colforsin results in increased abundance of Cyclic AMP]]; Dimaprit inhibits the reaction [HRH2 protein promotes the reaction [Dinoprostone results in increased abundance of Cyclic AMP]]; HRH2 protein promotes the reaction [Colforsin results in increased abundance of Cyclic AMP]; HRH2 protein promotes the reaction [Dinoprostone results in increased abundance of Cyclic AMP]		 CTD PMID:9187264 PMID:9681472 PMID:15843518 NCBI chr 5:175,658,071...175,710,756
Ensembl chr 5:175,658,030...175,710,756 		JBrowse link
G HRH3 histamine receptor H3 multiple interactions ISO [imetit results in increased activity of HRH3 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; ciproxifan inhibits the reaction [[imetit results in increased activity of HRH3 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; Pertussis Toxin inhibits the reaction [[imetit results in increased activity of HRH3 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; thioperamide inhibits the reaction [[imetit results in increased activity of HRH3 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]] CTD PMID:21276809 NCBI chr20:62,214,960...62,220,278
Ensembl chr20:62,214,960...62,220,278 		JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 increases expression ISO Cyclic AMP results in increased expression of HSD3B1 mRNA CTD PMID:25576683 NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054 		JBrowse link
G HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 increases expression EXP Cyclic AMP results in increased expression of HSD3B2 mRNA CTD PMID:18490834 NCBI chr 1:119,414,931...119,423,034
Ensembl chr 1:119,414,931...119,423,035 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A multiple interactions EXP [JB-788 binds to and results in increased activity of HTR1A protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; Arachidonic Acid metabolite inhibits the reaction [HTR1A protein inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; HTR1A protein inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; Melitten inhibits the reaction [HTR1A protein inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]] CTD PMID:11356925 PMID:20580787 NCBI chr 5:63,957,874...63,962,445
Ensembl chr 5:63,957,874...63,962,507 		JBrowse link
G HTR1B 5-hydroxytryptamine receptor 1B multiple interactions EXP HTR1B affects the reaction [almotriptan inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]] CTD PMID:11134654 NCBI chr 6:77,460,924...77,463,491
Ensembl chr 6:77,460,924...77,463,491 		JBrowse link
G HTR6 5-hydroxytryptamine receptor 6 increases abundance
multiple interactions		 ISO HTR6 protein results in increased abundance of Cyclic AMP
Serotonin promotes the reaction [HTR6 protein results in increased abundance of Cyclic AMP]		 CTD PMID:11406289 NCBI chr 1:19,664,875...19,680,966
Ensembl chr 1:19,664,875...19,680,966 		JBrowse link
G HTR7 5-hydroxytryptamine receptor 7 increases abundance
multiple interactions		 EXP HTR7 results in increased abundance of Cyclic AMP
[3,N-dimethyl-N-(1-methyl-3-(4-methylpiperidin-1-yl)propyl)benzenesulfonamide binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]; [5-carboxamidotryptamine binds to and results in increased activity of HTR7 protein] which results in increased abundance of Cyclic AMP; [5-Methoxytryptamine binds to and results in increased activity of HTR7 protein] which results in increased abundance of Cyclic AMP; [Bromocriptine binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [Clozapine binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]; [Ketanserin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]; [Lisuride binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [mesulergine binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]; [Metergoline binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]; [Metergoline binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [Methiothepin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [Methiothepin binds to and results in decreased activity of HTR7 protein] which results in decreased abundance of Cyclic AMP; [Methoxydimethyltryptamines binds to and results in increased activity of HTR7 protein] which results in increased abundance of Cyclic AMP; [Mianserin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]; [Paliperidone Palmitate binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [Risperidone binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [Ritanserin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]; [Serotonin binds to and results in increased activity of HTR7 protein] which results in increased abundance of Cyclic AMP; [Spiperone binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]; [volinanserin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]		 CTD PMID:10720076 PMID:14578406 PMID:19509219 NCBI chr10:90,740,823...90,858,039
Ensembl chr10:90,740,823...90,858,039 		JBrowse link
G HTRA1 HtrA serine peptidase 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of HTRA1 mRNA] CTD PMID:19414516 NCBI chr10:122,461,553...122,514,907
Ensembl chr10:122,458,551...122,514,907 		JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 increases abundance
multiple interactions		 ISO IDH2 protein mutant form results in increased abundance of Cyclic AMP
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Cyclic AMP]		 CTD PMID:27469509 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477 		JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 multiple interactions EXP 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of IDO1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of IDO1 protein]; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of IDO1 mRNA; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of IDO1 protein CTD PMID:32781018 NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790 		JBrowse link
G IER3 immediate early response 3 multiple interactions
affects response to substance		 ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of IER3 mRNA]
IER3 protein affects the susceptibility to Cyclic AMP
[[IER3 protein affects the chemical synthesis of Reactive Oxygen Species] which results in increased expression of GNAI2] which results in decreased chemical synthesis of Cyclic AMP; IER3 protein affects the reaction [Isoproterenol results in increased abundance of Cyclic AMP]; Pertussis Toxin affects the reaction [IER3 protein affects the reaction [Isoproterenol results in increased abundance of Cyclic AMP]]		 CTD PMID:19414516 PMID:20713914 NCBI chr 6:30,743,199...30,744,547
Ensembl chr 6:30,743,199...30,744,548 		JBrowse link
G IFNG interferon gamma multiple interactions EXP 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased abundance of Kynurenine]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of AHR mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1A1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1B1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of IDO1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of IDO1 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of TDO2 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [IFNG protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [IFNG protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]]; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased abundance of Kynurenine; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of AHR mRNA; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1A1 mRNA; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of CYP1B1 mRNA; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of IDO1 mRNA; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of IDO1 protein; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of TDO2 mRNA; IFNG protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; IFNG protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; IFNG protein promotes the reaction [Tryptophan promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]]; IFNG protein promotes the reaction [Tryptophan promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]] CTD PMID:32781018 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 multiple interactions EXP 2-hydroxyestradiol promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [IFNG protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Kynurenine promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tryptophan promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]]; 4-hydroxyestradiol promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; [Cyclic AMP co-treated with Estradiol co-treated with Progesterone] results in increased expression of IGFBP1 mRNA; [Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA; Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; IFNG protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; IFNG protein promotes the reaction [Tryptophan promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]]; Kynurenine promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; NAD inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA]; Tryptophan promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA] CTD PMID:31953017 PMID:32446389 PMID:32781018 NCBI chr 7:45,888,488...45,893,660
Ensembl chr 7:45,888,360...45,893,660 		JBrowse link
G IGFBP5 insulin like growth factor binding protein 5 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of IGFBP5 mRNA] CTD PMID:19414516 NCBI chr 2:216,672,105...216,695,549
Ensembl chr 2:216,672,105...216,695,549 		JBrowse link
G IL12A interleukin 12A multiple interactions EXP Cyclic AMP promotes the reaction [[Histamine results in increased activity of HRH2 protein] which results in decreased expression of IL12A protein] CTD PMID:15843518 NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019 		JBrowse link
G IL12B interleukin 12B multiple interactions EXP Cyclic AMP promotes the reaction [[Histamine results in increased activity of HRH2 protein] which results in decreased expression of IL12B protein] CTD PMID:15843518 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G IL15RA interleukin 15 receptor subunit alpha multiple interactions
decreases expression		 ISO [Metformin co-treated with Cyclic AMP] results in decreased expression of IL15RA mRNA; PPARGC1A mutant form inhibits the reaction [Cyclic AMP results in decreased expression of IL15RA mRNA] CTD PMID:22117073 NCBI chr10:5,948,900...5,978,741
Ensembl chr10:5,943,639...5,978,187 		JBrowse link
G IL17RE interleukin 17 receptor E multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of IL17RE mRNA] CTD PMID:19414516 NCBI chr 3:9,902,093...9,916,402
Ensembl chr 3:9,902,612...9,916,402 		JBrowse link
G IL1B interleukin 1 beta multiple interactions
increases abundance		 EXP
ISO		 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone promotes the reaction [IL1B protein results in increased abundance of Cyclic AMP]; Dipyridamole promotes the reaction [IL1B protein results in increased abundance of Cyclic AMP]; Ibuprofen inhibits the reaction [IL1B protein results in increased abundance of Cyclic AMP]; KT 5720 inhibits the reaction [Dipyridamole promotes the reaction [IL1B protein results in increased abundance of Cyclic AMP]]; KT 5823 inhibits the reaction [Dipyridamole promotes the reaction [IL1B protein results in increased abundance of Cyclic AMP]]; Rolipram promotes the reaction [IL1B protein results in increased abundance of Cyclic AMP]
Cyclic AMP inhibits the reaction [IL1B protein results in increased expression of CRP mRNA]; Cyclic AMP inhibits the reaction [IL1B protein results in increased expression of HP mRNA]; Cyclic AMP promotes the reaction [IL1B protein results in increased expression of IL1RN mRNA]		 CTD PMID:8904084 PMID:17709599 PMID:22117073 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RN interleukin 1 receptor antagonist multiple interactions
increases expression		 ISO Cyclic AMP promotes the reaction [IL1B protein results in increased expression of IL1RN mRNA]; Cyclic AMP promotes the reaction [Metformin results in increased expression of IL1RN mRNA]; Metformin promotes the reaction [Cyclic AMP results in increased expression of IL1RN mRNA]; PPARGC1A mutant form inhibits the reaction [Cyclic AMP results in increased expression of IL1RN mRNA] CTD PMID:22117073 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL4 interleukin 4 increases chemical synthesis
multiple interactions		 EXP IL4 protein results in increased chemical synthesis of Cyclic AMP
Ketoconazole inhibits the reaction [IL4 protein results in increased chemical synthesis of Cyclic AMP]		 CTD PMID:12230500 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL6 interleukin 6 increases expression ISO Cyclic AMP analog results in increased expression of IL6 mRNA CTD PMID:10469353 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INHBA inhibin subunit beta A increases secretion EXP Cyclic AMP results in increased secretion of INHBA protein CTD PMID:20074812 NCBI chr 7:41,685,114...41,705,406
Ensembl chr 7:41,667,168...41,705,834 		JBrowse link
G INHBE inhibin subunit beta E multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of INHBE mRNA CTD PMID:33713149 NCBI chr12:57,455,307...57,458,025
Ensembl chr12:57,452,323...57,459,280 		JBrowse link
G INS-IGF2 INS-IGF2 readthrough multiple interactions ISO [Theophylline co-treated with INS1 protein] results in decreased abundance of Cyclic AMP; INS1 protein inhibits the reaction [[Theophylline co-treated with Norepinephrine] results in increased abundance of Cyclic AMP]; INS1 protein inhibits the reaction [[Theophylline co-treated with POMC protein] results in increased abundance of Cyclic AMP]
[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]; [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]; arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]; arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]]; INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]; INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]		 CTD PMID:4306506 PMID:26847930 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209 		JBrowse link
G IQGAP1 IQ motif containing GTPase activating protein 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of IQGAP1 mRNA] CTD PMID:19414516 NCBI chr15:90,388,242...90,502,239
Ensembl chr15:90,388,242...90,502,239 		JBrowse link
G IRF6 interferon regulatory factor 6 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of IRF6 mRNA] CTD PMID:19414516 NCBI chr 1:209,785,617...209,806,142
Ensembl chr 1:209,785,617...209,806,175 		JBrowse link
G ITGB1 integrin subunit beta 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of ITGB1 mRNA] CTD PMID:19414516 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [Etoposide co-treated with Cyclic AMP] results in increased expression of JUN mRNA CTD PMID:10711420 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of KCND2 mRNA] CTD PMID:19414516 NCBI chr 7:120,272,908...120,750,337
Ensembl chr 7:120,273,175...120,750,337 		JBrowse link
G KIF15 kinesin family member 15 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of KIF15 mRNA] CTD PMID:19414516 NCBI chr 3:44,761,794...44,868,687
Ensembl chr 3:44,761,721...44,873,376 		JBrowse link
G KNG1 kininogen 1 increases abundance ISO KNG1 results in increased abundance of Cyclic AMP CTD PMID:15750287 NCBI chr 3:186,717,359...186,744,410
Ensembl chr 3:186,717,348...186,744,410 		JBrowse link
G LAMP1 lysosomal associated membrane protein 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of LAMP1 mRNA] CTD PMID:19414516 NCBI chr13:113,297,239...113,323,672
Ensembl chr13:113,297,239...113,323,672 		JBrowse link
G LEF1 lymphoid enhancer binding factor 1 multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of LEF1 mRNA CTD PMID:33713149 NCBI chr 4:108,047,548...108,168,932
Ensembl chr 4:108,047,545...108,168,956 		JBrowse link
G LEP leptin increases abundance
increases expression
multiple interactions		 EXP
ISO		 LEP protein results in increased abundance of Cyclic AMP
Cyclic AMP analog results in increased expression of LEP mRNA
3-(5-tert-butylisoxazol-3-yl)-2-((3-chlorophenyl)hydrazono)-3-oxopropionitrile inhibits the reaction [Cyclic AMP analog results in increased expression of LEP mRNA]		 CTD PMID:11342529 PMID:27381457 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G LHB luteinizing hormone subunit beta multiple interactions
increases abundance
increases chemical synthesis
affects secretion		 ISO
EXP		 5,8,11,14-Eicosatetraynoic Acid inhibits the reaction [LHB protein results in increased abundance of Cyclic AMP]; [Flufenamic Acid results in decreased abundance of Cyclic AMP] which results in decreased expression of LHB mRNA; [LHB protein co-treated with Guanylyl Imidodiphosphate] results in increased chemical synthesis of Cyclic AMP; CRH protein inhibits the reaction [[LHB protein co-treated with Guanylyl Imidodiphosphate] results in increased chemical synthesis of Cyclic AMP]; CRH protein inhibits the reaction [LHB protein results in increased chemical synthesis of Cyclic AMP]; Masoprocol inhibits the reaction [LHB protein results in increased abundance of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [[LHB protein co-treated with Guanylyl Imidodiphosphate] results in increased chemical synthesis of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [LHB protein results in increased chemical synthesis of Cyclic AMP]
LHB protein affects the secretion of Cyclic AMP
[LHB protein affects the secretion of Cyclic AMP] which results in increased secretion of Progesterone; [LHB protein co-treated with 1-Methyl-3-isobutylxanthine] results in increased abundance of Cyclic AMP; DDT inhibits the reaction [LHB protein results in increased abundance of Cyclic AMP]		 CTD PMID:2153673 PMID:6430271 PMID:8404651 PMID:23071612 PMID:33638691 NCBI chr19:49,015,980...49,019,498
Ensembl chr19:49,015,980...49,017,091 		JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor multiple interactions EXP
ISO		 [CGB3 protein results in increased activity of LHCGR protein] which results in increased abundance of Cyclic AMP; ESR1 protein promotes the reaction [[CGB3 protein results in increased activity of LHCGR protein] which results in increased abundance of Cyclic AMP]; ESR2 protein promotes the reaction [[CGB3 protein results in increased activity of LHCGR protein] which results in increased abundance of Cyclic AMP]; Estradiol inhibits the reaction [[CGB3 protein results in increased activity of LHCGR protein] which results in increased abundance of Cyclic AMP]
[ESR2 gene mutant form results in decreased expression of LHCGR protein] inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]		 CTD PMID:19766106 PMID:20378682 NCBI chr 2:48,686,774...48,755,724
Ensembl chr 2:48,686,774...48,755,730 		JBrowse link
G LIPE lipase E, hormone sensitive type increases activity EXP Cyclic AMP results in increased activity of LIPE protein CTD PMID:7155675 NCBI chr19:42,401,514...42,427,388
Ensembl chr19:42,401,514...42,427,388 		JBrowse link
G LMNA lamin A/C multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of LMNA mRNA] CTD PMID:19414516 NCBI chr 1:156,082,573...156,140,081
Ensembl chr 1:156,082,573...156,140,081 		JBrowse link
G LURAP1L leucine rich adaptor protein 1 like multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of LURAP1L mRNA] CTD PMID:19414516 NCBI chr 9:12,775,020...12,823,060
Ensembl chr 9:12,775,020...12,823,060 		JBrowse link
G MAN1A1 mannosidase alpha class 1A member 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of MAN1A mRNA] CTD PMID:19414516 NCBI chr 6:119,177,205...119,350,605
Ensembl chr 6:119,177,205...119,349,761 		JBrowse link
G MAP2 microtubule associated protein 2 multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of MAP2 protein CTD PMID:33713149 NCBI chr 2:209,424,047...209,734,112
Ensembl chr 2:209,424,047...209,734,147 		JBrowse link
G MC2R melanocortin 2 receptor multiple interactions EXP [acetyl methyl tetramethyl tetralin co-treated with Cyclic AMP] results in decreased expression of MC2R mRNA CTD PMID:23084589 NCBI chr18:13,882,044...13,915,707
Ensembl chr18:13,882,044...13,915,707 		JBrowse link
G MSANTD3 Myb/SANT DNA binding domain containing 3 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of MSANTD3 mRNA] CTD PMID:19414516 NCBI chr 9:100,427,143...100,451,734
Ensembl chr 9:100,427,143...100,451,734 		JBrowse link
G NDUFB11 NADH:ubiquinone oxidoreductase subunit B11 increases phosphorylation
multiple interactions		 EXP Cyclic AMP results in increased phosphorylation of NDUFB11 protein
Zalcitabine inhibits the reaction [Cyclic AMP results in increased phosphorylation of NDUFB11 protein]; Zidovudine inhibits the reaction [Cyclic AMP results in increased phosphorylation of NDUFB11 protein]		 CTD PMID:17904600 NCBI chr  X:47,142,216...47,145,491
Ensembl chr  X:47,142,071...47,145,466 		JBrowse link
G NGF nerve growth factor multiple interactions
increases expression		 ISO [Colforsin results in increased abundance of Cyclic AMP] which results in increased expression of NGF mRNA; [Isoproterenol results in increased abundance of Cyclic AMP] which results in increased expression of NGF mRNA
Cyclic AMP results in increased expression of NGF mRNA		 CTD PMID:2174743 PMID:2853697 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770 		JBrowse link
G NOG noggin multiple interactions ISO NOG protein inhibits the reaction [Octreotide inhibits the reaction [FSHB protein results in increased abundance of Cyclic AMP]]; NOG protein inhibits the reaction [pasireotide inhibits the reaction [FSHB protein results in increased abundance of Cyclic AMP]] CTD PMID:23137853 NCBI chr17:56,593,699...56,595,611
Ensembl chr17:56,593,699...56,595,611 		JBrowse link
G NPL N-acetylneuraminate pyruvate lyase multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of NPL mRNA] CTD PMID:19414516 NCBI chr 1:182,789,773...182,830,384
Ensembl chr 1:182,789,293...182,830,384 		JBrowse link
G NR0B1 nuclear receptor subfamily 0 group B member 1 decreases expression
multiple interactions		 ISO Cyclic AMP results in decreased expression of NR0B1 mRNA
Verapamil promotes the reaction [Cyclic AMP results in decreased expression of NR0B1 mRNA]		 CTD PMID:19822634 NCBI chr  X:30,304,206...30,309,390
Ensembl chr  X:30,304,206...30,309,390 		JBrowse link
G NTAN1 N-terminal asparagine amidase multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of NTAN1 mRNA] CTD PMID:19414516 NCBI chr16:15,037,857...15,056,074
Ensembl chr16:15,037,854...15,056,079 		JBrowse link
G OAT ornithine aminotransferase increases activity
multiple interactions
increases expression		 ISO Cyclic AMP results in increased activity of OAT protein
Deoxyglucose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Dihydroxyacetone inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Fructose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Fructose inhibits the reaction [Cyclic AMP results in increased expression of OAT mRNA]; Galactose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Glucose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Glycerol inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Inositol inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Mannitol inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Mannose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Rhamnose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Ribose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Sorbitol inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Sorbose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Xylitol inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]		 CTD PMID:2824512 PMID:2827574 NCBI chr10:124,397,303...124,418,923
Ensembl chr10:124,397,303...124,418,976 		JBrowse link
G OPRM1 opioid receptor mu 1 multiple interactions EXP [7-benzylidenenaltrexone binds to and results in decreased activity of OPRM1 protein] which results in increased expression of Cyclic AMP; [[Naloxone binds to and results in decreased activity of OPRM1 protein] which co-treated with Morphine] results in increased expression of Cyclic AMP; [[Naltrexone binds to and results in decreased activity of OPRM1 protein] which co-treated with Morphine] results in increased expression of Cyclic AMP; [chlornaltrexamine binds to and results in decreased activity of OPRM1 protein] which results in increased expression of Cyclic AMP; [clocinnamox binds to and results in decreased activity of OPRM1 protein] which results in increased expression of Cyclic AMP; [nalmefene binds to and results in decreased activity of OPRM1 protein] which results in increased expression of Cyclic AMP CTD PMID:11413242 NCBI chr 6:154,010,496...154,246,867
Ensembl chr 6:154,010,496...154,246,867 		JBrowse link
G OR51A2 olfactory receptor family 51 subfamily A member 2 multiple interactions ISO [pelargonic acid results in increased activity of OR51A5 protein] which results in increased abundance of Cyclic AMP; octanoic acid promotes the reaction [[pelargonic acid results in increased activity of OR51A5 protein] which results in increased abundance of Cyclic AMP] CTD PMID:15598656 NCBI chr11:4,954,772...4,955,713
Ensembl chr11:4,954,772...4,955,713 		JBrowse link
G OR5D18 olfactory receptor family 5 subfamily D member 18 multiple interactions ISO [[Eugenol results in increased activity of OR5D18 protein] which results in increased abundance of Cyclic AMP] which results in increased expression of EGR1 mRNA; [Eugenol binds to and results in increased activity of OR5D18 protein] which results in increased abundance of Cyclic AMP; [Eugenol results in increased activity of OR5D18 protein] which results in increased abundance of Cyclic AMP CTD PMID:12767924 PMID:15716417 NCBI chr11:55,819,630...55,820,571
Ensembl chr11:55,819,630...55,820,571 		JBrowse link
G OR6J1 olfactory receptor family 6 subfamily J member 1 multiple interactions EXP
ISO		 [[GNAL protein results in increased susceptibility to citronellal] which results in increased activity of OR6E1 protein] which results in increased abundance of Cyclic AMP; [[GNAS protein results in increased susceptibility to citronellal] which results in increased activity of OR6E1 protein] which results in increased abundance of Cyclic AMP
[citronellal results in increased activity of OR6E1 protein] which results in increased abundance of Cyclic AMP		 CTD PMID:15598656 NCBI chr14:22,630,929...22,644,352
Ensembl chr14:22,630,929...22,644,352 		JBrowse link
G OS9 OS9 endoplasmic reticulum lectin multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of OS9 mRNA] CTD PMID:19414516 NCBI chr12:57,694,132...57,721,557
Ensembl chr12:57,693,841...57,728,342 		JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 increases expression
multiple interactions		 ISO Cyclic AMP results in increased expression of PCK1 mRNA
[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein; [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]; arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]]; INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]
[Dexamethasone co-treated with Cyclic AMP] results in increased expression of PCK1 mRNA; [Glucagon co-treated with Cyclic AMP] results in increased expression of PCK1 mRNA; Fatty Acids analog inhibits the reaction [[Dexamethasone co-treated with Cyclic AMP] results in increased expression of PCK1 mRNA]; Fatty Acids analog inhibits the reaction [[Glucagon co-treated with Cyclic AMP] results in increased expression of PCK1 mRNA]; Hydrogen Peroxide inhibits the reaction [[Dexamethasone co-treated with Cyclic AMP] results in increased expression of PCK1 mRNA]; ochratoxin A inhibits the reaction [Cyclic AMP results in increased expression of PCK1 mRNA]; sodium arsenite inhibits the reaction [[Dexamethasone co-treated with Cyclic AMP] results in increased expression of PCK1 mRNA]		 CTD PMID:2569870 PMID:8971075 PMID:10446394 PMID:22117073 PMID:22676303 More... NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121 		JBrowse link
G PDE10A phosphodiesterase 10A multiple interactions
increases hydrolysis		 EXP Cyclic AMP inhibits the reaction [PDE10A protein results in increased hydrolysis of Cyclic GMP]; Cyclic GMP inhibits the reaction [PDE10A protein results in increased hydrolysis of Cyclic AMP]; Dipyridamole inhibits the reaction [PDE10A protein results in increased hydrolysis of Cyclic AMP] CTD PMID:10373451 NCBI chr 6:165,327,289...165,988,052
Ensembl chr 6:165,327,287...165,988,117 		JBrowse link
G PDE11A phosphodiesterase 11A increases hydrolysis EXP PDE11A protein results in increased hydrolysis of Cyclic AMP CTD PMID:10725373 NCBI chr 2:177,623,244...178,108,339
Ensembl chr 2:177,623,244...178,108,339 		JBrowse link
G PDE4B phosphodiesterase 4B multiple interactions ISO
EXP		 [[S-Adenosylmethionine inhibits the reaction [Lipopolysaccharides results in increased expression of PDE4B mRNA]] which results in increased abundance of Cyclic AMP] inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; [S-Adenosylmethionine inhibits the reaction [Lipopolysaccharides results in increased expression of PDE4B mRNA]] which results in increased abundance of Cyclic AMP
[Bresol results in decreased activity of PDE4B protein] which results in increased abundance of Cyclic AMP; Cyclic AMP inhibits the reaction [DISC1 protein binds to PDE4B protein]		 CTD PMID:16293762 PMID:21266552 PMID:21854221 NCBI chr 1:65,792,510...66,374,579
Ensembl chr 1:65,792,514...66,374,579 		JBrowse link
G PDE7A phosphodiesterase 7A multiple interactions
increases hydrolysis		 EXP 1-Methyl-3-isobutylxanthine inhibits the reaction [PDE7A protein results in increased hydrolysis of Cyclic AMP]; Dipyridamole inhibits the reaction [PDE7A protein results in increased hydrolysis of Cyclic AMP]; Papaverine inhibits the reaction [PDE7A protein results in increased hydrolysis of Cyclic AMP]; SCH 51866 inhibits the reaction [PDE7A protein results in increased hydrolysis of Cyclic AMP] CTD PMID:10618442 PMID:10814504 NCBI chr 8:65,714,334...65,842,064
Ensembl chr 8:65,714,334...65,842,322 		JBrowse link
G PDE7B phosphodiesterase 7B increases hydrolysis
multiple interactions		 EXP
ISO		 PDE7B protein results in increased hydrolysis of Cyclic AMP
1-Methyl-3-isobutylxanthine inhibits the reaction [PDE7B protein results in increased hydrolysis of Cyclic AMP]; Dipyridamole inhibits the reaction [PDE7B protein results in increased hydrolysis of Cyclic AMP]; E 4021 inhibits the reaction [PDE7B protein results in increased hydrolysis of Cyclic AMP]; SCH 51866 inhibits the reaction [PDE7B protein results in increased hydrolysis of Cyclic AMP]; vinpocetine inhibits the reaction [PDE7B protein results in increased hydrolysis of Cyclic AMP]
1-Methyl-3-isobutylxanthine inhibits the reaction [PDE7B protein results in increased hydrolysis of Cyclic AMP]; Dipyridamole inhibits the reaction [PDE7B protein results in increased hydrolysis of Cyclic AMP]; Papaverine inhibits the reaction [PDE7B protein results in increased hydrolysis of Cyclic AMP]; SCH 51866 inhibits the reaction [PDE7B protein results in increased hydrolysis of Cyclic AMP]		 CTD PMID:10618442 PMID:10814504 PMID:10872825 NCBI chr 6:135,851,701...136,195,574
Ensembl chr 6:135,851,701...136,195,574 		JBrowse link
G PDE8A phosphodiesterase 8A multiple interactions
increases metabolic processing
increases hydrolysis		 EXP
ISO		 Dipyridamole inhibits the reaction [PDE8A protein results in increased metabolism of Cyclic AMP]; E 4021 inhibits the reaction [PDE8A protein results in increased metabolism of Cyclic AMP]
PDE8A protein results in increased hydrolysis of Cyclic AMP
Dipyridamole inhibits the reaction [PDE8A protein results in increased hydrolysis of Cyclic AMP]		 CTD PMID:9671792 PMID:12681444 NCBI chr15:84,980,467...85,139,142
Ensembl chr15:84,980,440...85,139,145 		JBrowse link
G PDE8B phosphodiesterase 8B multiple interactions
increases metabolic processing
increases hydrolysis		 EXP 9-(2-hydroxy-3-nonyl)adenine inhibits the reaction [PDE8B protein results in increased metabolism of Cyclic AMP]; Dipyridamole inhibits the reaction [PDE8B protein results in increased hydrolysis of Cyclic AMP]; Dipyridamole inhibits the reaction [PDE8B protein results in increased metabolism of Cyclic AMP]; E 4021 inhibits the reaction [PDE8B protein results in increased metabolism of Cyclic AMP]; Sildenafil Citrate inhibits the reaction [PDE8B protein results in increased metabolism of Cyclic AMP] CTD PMID:9784418 PMID:12681444 NCBI chr 5:77,086,715...77,428,256
Ensembl chr 5:77,210,449...77,428,256
Ensembl chr 5:77,210,449...77,428,256 		JBrowse link
G PDE9A phosphodiesterase 9A increases hydrolysis EXP PDE9A protein results in increased hydrolysis of Cyclic AMP CTD PMID:9624146 NCBI chr21:42,653,621...42,775,509
Ensembl chr21:42,653,621...42,775,509 		JBrowse link
G PDK1 pyruvate dehydrogenase kinase 1 affects abundance
multiple interactions		 ISO PDK1 protein affects the abundance of Cyclic AMP
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester affects the reaction [PDK1 protein affects the abundance of Cyclic AMP]; [PDK1 protein affects the susceptibility to Colforsin] which affects the abundance of Cyclic AMP; N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide affects the reaction [PDK1 protein affects the abundance of Cyclic AMP]; tubacin affects the reaction [[PDK1 protein affects the susceptibility to Colforsin] which affects the abundance of Cyclic AMP]; tubacin affects the reaction [PDK1 protein affects the abundance of Cyclic AMP]; tubastatin A affects the reaction [PDK1 protein affects the abundance of Cyclic AMP]; W 7 affects the reaction [PDK1 protein affects the abundance of Cyclic AMP]		 CTD PMID:28887310 NCBI chr 2:172,555,373...172,724,312
Ensembl chr 2:172,555,373...172,608,669 		JBrowse link
G PEBP1 phosphatidylethanolamine binding protein 1 multiple interactions EXP PEBP1 protein promotes the reaction [Isoproterenol results in increased abundance of Cyclic AMP] CTD PMID:26670611 NCBI chr12:118,136,124...118,145,584
Ensembl chr12:118,136,124...118,145,584 		JBrowse link
G PFN2 profilin 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of PFN2 mRNA] CTD PMID:19414516 NCBI chr 3:149,964,904...149,970,895
Ensembl chr 3:149,964,904...150,050,788 		JBrowse link
G PGR progesterone receptor multiple interactions EXP Cyclic AMP inhibits the reaction [[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of PGR mRNA]] CTD PMID:37552060 NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813 		JBrowse link
G PKIA cAMP-dependent protein kinase inhibitor alpha multiple interactions EXP [PRKACB protein mutant form affects the susceptibility to Cyclic AMP] results in decreased stability of [PRKACB protein mutant form binds to PKIA protein] CTD PMID:29669941 NCBI chr 8:78,516,340...78,605,267
Ensembl chr 8:78,516,340...78,605,267 		JBrowse link
G PLA2G4A phospholipase A2 group IVA increases expression
multiple interactions		 ISO Cyclic AMP results in increased expression of PLA2G4A mRNA; Cyclic AMP results in increased expression of PLA2G4A protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cyclic AMP results in increased expression of PLA2G4A mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cyclic AMP results in increased expression of PLA2G4A protein]		 CTD PMID:22187434 NCBI chr 1:186,828,949...186,988,981
Ensembl chr 1:186,828,949...186,988,981 		JBrowse link
G POMC proopiomelanocortin multiple interactions
increases abundance		 ISO [Theophylline co-treated with POMC protein] results in increased abundance of Cyclic AMP; INS1 protein inhibits the reaction [[Theophylline co-treated with POMC protein] results in increased abundance of Cyclic AMP]
POMC protein modified form results in increased abundance of Cyclic AMP
Quercetin analog inhibits the reaction [POMC protein modified form results in increased abundance of Cyclic AMP]		 CTD PMID:4306506 PMID:26586997 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903 		JBrowse link
G POR cytochrome p450 oxidoreductase increases expression ISO Cyclic AMP results in increased expression of POR mRNA CTD PMID:25576683 NCBI chr 7:75,915,155...75,986,855
Ensembl chr 7:75,899,200...75,986,855 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha multiple interactions
increases expression		 ISO Cyclic AMP promotes the reaction [PPARGC1A protein binds to CYP2A5 promoter]; PPARGC1A mutant form inhibits the reaction [Cyclic AMP results in decreased expression of IL15RA mRNA]; PPARGC1A mutant form inhibits the reaction [Cyclic AMP results in increased expression of IL1RN mRNA]
[Dexamethasone co-treated with Cyclic AMP] results in increased expression of PPARGC1A mRNA; [Glucagon co-treated with Cyclic AMP] results in increased expression of PPARGC1A mRNA; Fatty Acids analog inhibits the reaction [[Dexamethasone co-treated with Cyclic AMP] results in increased expression of PPARGC1A mRNA]; Fatty Acids analog inhibits the reaction [[Dexamethasone co-treated with Cyclic AMP] results in increased phosphorylation of PPARGC1A protein]; Fatty Acids analog inhibits the reaction [[Glucagon co-treated with Cyclic AMP] results in increased expression of PPARGC1A mRNA]; Fatty Acids analog inhibits the reaction [[Glucagon co-treated with Cyclic AMP] results in increased phosphorylation of PPARGC1A protein]
Cyclic AMP results in increased expression of PPARGC1A mRNA		 CTD PMID:18602936 PMID:22117073 PMID:22676303 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G PPP1R14B protein phosphatase 1 regulatory inhibitor subunit 14B multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of PPP1R14B mRNA] CTD PMID:19414516 NCBI chr11:64,244,479...64,246,943
Ensembl chr11:64,244,479...64,246,943 		JBrowse link
G PRKACB protein kinase cAMP-activated catalytic subunit beta multiple interactions
affects response to substance		 EXP [PRKACB protein mutant form affects the susceptibility to Cyclic AMP] results in decreased stability of [PRKACB protein mutant form binds to PKIA protein]; [PRKACB protein mutant form affects the susceptibility to Cyclic AMP] results in decreased stability of [PRKACB protein mutant form binds to PRKAR1A protein] CTD PMID:29669941 NCBI chr 1:84,078,079...84,238,498
Ensembl chr 1:84,078,062...84,238,498 		JBrowse link
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha multiple interactions EXP [PRKACB protein mutant form affects the susceptibility to Cyclic AMP] results in decreased stability of [PRKACB protein mutant form binds to PRKAR1A protein] CTD PMID:29669941 NCBI chr17:68,413,623...68,551,316
Ensembl chr17:68,511,780...68,551,319 		JBrowse link
G PRKAR2A protein kinase cAMP-dependent type II regulatory subunit alpha multiple interactions ISO Clozapine inhibits the reaction [Cyclic AMP binds to PRKAR2A protein]; Haloperidol promotes the reaction [Cyclic AMP binds to PRKAR2A protein] CTD PMID:11907174 NCBI chr 3:48,744,591...48,847,874
Ensembl chr 3:48,744,597...48,847,874 		JBrowse link
G PRKAR2B protein kinase cAMP-dependent type II regulatory subunit beta multiple interactions ISO Clozapine inhibits the reaction [Cyclic AMP binds to PRKAR2B protein]; Haloperidol promotes the reaction [Cyclic AMP binds to PRKAR2B protein] CTD PMID:11907174 NCBI chr 7:107,044,705...107,161,811
Ensembl chr 7:107,044,705...107,161,811 		JBrowse link
G PRL prolactin multiple interactions
increases secretion		 ISO
EXP		 [Atrazine results in increased abundance of Cyclic AMP] which results in increased secretion of PRL protein
2-hydroxyestradiol promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [IFNG protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Kynurenine promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tryptophan promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]]; 4-hydroxyestradiol promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; [Cyclic AMP co-treated with Estradiol co-treated with Progesterone] results in increased expression of PRL mRNA; [Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA; Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; IFNG protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; IFNG protein promotes the reaction [Tryptophan promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]]; Kynurenine promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; Tryptophan promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]
Cyclic AMP results in increased secretion of PRL protein		 CTD PMID:20074812 PMID:23022511 PMID:31953017 PMID:32446389 PMID:32781018 NCBI chr 6:22,287,246...22,302,835
Ensembl chr 6:22,287,244...22,302,826 		JBrowse link
G PROK1 prokineticin 1 affects response to substance EXP PROK1 protein affects the susceptibility to Cyclic AMP CTD PMID:21546446 NCBI chr 1:110,451,149...110,457,358
Ensembl chr 1:110,451,149...110,457,358 		JBrowse link
G PTGDR2 prostaglandin D2 receptor 2 multiple interactions ISO [5-hydroxyindomethacin binds to PTGDR2 protein] which results in decreased abundance of Cyclic AMP; [Indomethacin binds to PTGDR2 protein] which results in decreased abundance of Cyclic AMP; [sulindac sulfide binds to PTGDR2 protein] which results in decreased abundance of Cyclic AMP CTD PMID:15563582 NCBI chr11:60,850,933...60,855,950
Ensembl chr11:60,850,933...60,855,950 		JBrowse link
G PTGER2 prostaglandin E receptor 2 multiple interactions EXP [Dinoprostone results in increased activity of PTGER2 protein] which results in increased chemical synthesis of Cyclic AMP; nickel sulfate promotes the reaction [[Dinoprostone results in increased activity of PTGER2 protein] which results in increased chemical synthesis of Cyclic AMP] CTD PMID:23526216 NCBI chr14:52,314,312...52,328,598
Ensembl chr14:52,314,305...52,328,598 		JBrowse link
G PTGER3 prostaglandin E receptor 3 multiple interactions ISO [Dinoprostone results in increased activity of PTGER3 protein] which results in decreased abundance of Cyclic AMP CTD PMID:10357836 NCBI chr 1:70,852,358...71,047,816
Ensembl chr 1:70,852,353...71,047,816 		JBrowse link
G PTGER4 prostaglandin E receptor 4 multiple interactions EXP [Dinoprostone results in increased activity of PTGER4 protein] which results in increased chemical synthesis of Cyclic AMP; nickel sulfate promotes the reaction [[Dinoprostone results in increased activity of PTGER4 protein] which results in increased chemical synthesis of Cyclic AMP] CTD PMID:23526216 NCBI chr 5:40,679,915...40,746,800
Ensembl chr 5:40,679,915...40,693,735 		JBrowse link
G PTGIR prostaglandin I2 receptor multiple interactions EXP [cicaprost results in increased activity of PTGIR protein] which results in increased abundance of Cyclic AMP; GNAS protein promotes the reaction [[cicaprost results in increased activity of PTGIR protein] which results in increased abundance of Cyclic AMP] CTD PMID:11895442 NCBI chr19:46,610,687...46,625,089
Ensembl chr19:46,620,468...46,625,089 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased abundance of Cyclic AMP] CTD PMID:21873648 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTH parathyroid hormone increases abundance ISO PTH protein results in increased abundance of Cyclic AMP CTD PMID:26851681 NCBI chr11:13,492,054...13,496,181
Ensembl chr11:13,492,054...13,496,181 		JBrowse link
G PTHLH parathyroid hormone like hormone increases abundance EXP PTHLH protein results in increased abundance of Cyclic AMP CTD PMID:10600786 NCBI chr12:27,958,084...27,972,733
Ensembl chr12:27,958,084...27,972,733 		JBrowse link
G PTMA prothymosin alpha increases abundance ISO PTMA protein results in increased abundance of Cyclic AMP CTD PMID:9147362 NCBI chr 2:231,708,525...231,713,551
Ensembl chr 2:231,706,895...231,713,551 		JBrowse link
G RAB3B RAB3B, member RAS oncogene family multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of RAB3B mRNA] CTD PMID:19414516 NCBI chr 1:51,907,956...51,990,700
Ensembl chr 1:51,907,956...51,990,700 		JBrowse link
G RAP1A RAP1A, member of RAS oncogene family increases activity EXP Cyclic AMP results in increased activity of RAP1A protein CTD PMID:24701590 NCBI chr 1:111,542,009...111,716,691
Ensembl chr 1:111,542,218...111,716,691 		JBrowse link
G RAP1B RAP1B, member of RAS oncogene family multiple interactions ISO
EXP		 [Pentoxifylline results in increased abundance of Cyclic AMP] results in increased abundance of [RAP1B protein binds to Guanosine Triphosphate] CTD PMID:21693435 NCBI chr12:68,610,899...68,671,901
Ensembl chr12:68,610,855...68,671,901 		JBrowse link
G RBFOX3 RNA binding fox-1 homolog 3 multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of RBFOX3 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of RBFOX3 protein CTD PMID:33713149 NCBI chr17:79,089,345...79,665,571
Ensembl chr17:79,089,345...79,611,051 		JBrowse link
G RBM12 RNA binding motif protein 12 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of RBM12 mRNA] CTD PMID:19414516 NCBI chr20:35,648,925...35,664,900
Ensembl chr20:35,648,925...35,664,956 		JBrowse link
G RGL1 ral guanine nucleotide dissociation stimulator like 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of RGL1 mRNA] CTD PMID:19414516 NCBI chr 1:183,636,109...183,928,532
Ensembl chr 1:183,636,085...183,928,532 		JBrowse link
G RMDN3 regulator of microtubule dynamics 3 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of RMDN3 mRNA] CTD PMID:19414516 NCBI chr15:40,735,887...40,755,254
Ensembl chr15:40,735,884...40,755,851 		JBrowse link
G S100B S100 calcium binding protein B multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of S100B mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of S100B protein CTD PMID:33713149 NCBI chr21:46,598,604...46,605,082
Ensembl chr21:46,598,604...46,605,208 		JBrowse link
G SCN2A sodium voltage-gated channel alpha subunit 2 multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SCN2A mRNA CTD PMID:33713149 NCBI chr 2:165,239,414...165,392,304
Ensembl chr 2:165,194,993...165,392,310 		JBrowse link
G SCT secretin multiple interactions
increases abundance		 ISO Epinephrine inhibits the reaction [SCT protein results in increased abundance of Cyclic AMP] CTD PMID:6312992 NCBI chr11:626,309...627,181
Ensembl chr11:626,309...627,181 		JBrowse link
G SDC1 syndecan 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of SDC1 mRNA] CTD PMID:19414516 NCBI chr 2:20,200,797...20,225,475
Ensembl chr 2:20,200,797...20,225,433 		JBrowse link
G SLC17A6 solute carrier family 17 member 6 multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SLC17A6 mRNA CTD PMID:33713149 NCBI chr11:22,338,381...22,379,503
Ensembl chr11:22,338,381...22,379,503 		JBrowse link
G SLC17A7 solute carrier family 17 member 7 multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SLC17A7 protein CTD PMID:33713149 NCBI chr19:49,429,401...49,441,527
Ensembl chr19:49,429,401...49,442,360 		JBrowse link
G SLC22A8 solute carrier family 22 member 8 affects transport EXP SLC22A8 protein affects the transport of Cyclic AMP CTD PMID:11306713 NCBI chr11:62,992,824...63,015,841
Ensembl chr11:62,989,154...63,015,841 		JBrowse link
G SLC2A5 solute carrier family 2 member 5 affects expression
multiple interactions		 EXP
ISO		 Cyclic AMP affects the expression of SLC2A5 mRNA
[[Colforsin results in increased abundance of Cyclic AMP] which results in increased expression of SLC2A5 protein] which results in increased uptake of Fructose; [Colforsin results in increased abundance of Cyclic AMP] which results in increased expression of SLC2A5 protein
[Fructose results in increased abundance of Cyclic AMP] which results in increased stability of SLC2A5 mRNA		 CTD PMID:8037665 PMID:8554516 PMID:12820898 NCBI chr 1:9,035,106...9,094,195
Ensembl chr 1:9,035,106...9,088,478 		JBrowse link
G SLC4A2 solute carrier family 4 member 2 multiple interactions ISO Nitric Oxide inhibits the reaction [SLC4A2 protein promotes the reaction [Cyclic AMP results in increased transport of Bicarbonates]]; SLC4A2 protein promotes the reaction [Cyclic AMP results in increased transport of Bicarbonates] CTD PMID:12612912 NCBI chr 7:151,058,200...151,076,527
Ensembl chr 7:151,057,210...151,076,526 		JBrowse link
G SMOC2 SPARC related modular calcium binding 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of SMOC2 mRNA] CTD PMID:19414516 NCBI chr 6:168,441,184...168,667,992
Ensembl chr 6:168,441,151...168,673,445 		JBrowse link
G SNX33 sorting nexin 33 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of SNX33 mRNA] CTD PMID:19414516 NCBI chr15:75,647,912...75,662,301
Ensembl chr15:75,647,912...75,662,301 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 multiple interactions EXP 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [[[Colforsin co-treated with Rolipram] results in increased abundance of Cyclic AMP] which results in increased expression of SOCS3 protein]; [[Colforsin co-treated with Rolipram] results in increased abundance of Cyclic AMP] which results in increased expression of SOCS3 protein; dorsomorphin inhibits the reaction [[[Colforsin co-treated with Rolipram] results in increased abundance of Cyclic AMP] which results in increased expression of SOCS3 protein] CTD PMID:23782265 NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077 		JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions EXP WNT5A protein affects the reaction [[Medroxyprogesterone Acetate results in increased abundance of Cyclic AMP] which results in increased expression of SOD2 mRNA] CTD PMID:20685861 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SRD5A1 steroid 5 alpha-reductase 1 increases expression ISO Cyclic AMP results in increased expression of SRD5A1 mRNA CTD PMID:25576683 NCBI chr 5:6,633,440...6,674,386
Ensembl chr 5:6,633,290...6,676,539 		JBrowse link
G SST somatostatin multiple interactions EXP [SST protein co-treated with SSTR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP] CTD PMID:22056254 NCBI chr 3:187,668,912...187,670,394
Ensembl chr 3:187,668,912...187,670,394 		JBrowse link
G SSTR2 somatostatin receptor 2 multiple interactions EXP [64Cu-CB-TE2A-Y3-TATE co-treated with SSTR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP]; [SST protein co-treated with SSTR2 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP] CTD PMID:22056254 NCBI chr17:73,165,010...73,176,633
Ensembl chr17:73,165,010...73,176,633 		JBrowse link
G ST6GAL2 ST6 beta-galactoside alpha-2,6-sialyltransferase 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of ST6GAL2 mRNA] CTD PMID:19414516 NCBI chr 2:106,801,600...106,887,277
Ensembl chr 2:106,801,600...106,887,108 		JBrowse link
G STAR steroidogenic acute regulatory protein multiple interactions
increases expression		 ISO [Cyclic AMP co-treated with Verapamil] results in increased expression of STAR protein; Calcium inhibits the reaction [Cyclic AMP results in increased expression of STAR protein]; Diltiazem promotes the reaction [Cyclic AMP results in increased expression of STAR protein]; Isradipine promotes the reaction [Cyclic AMP results in increased expression of STAR protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [perfluorododecanoic acid inhibits the reaction [Cyclic AMP results in increased expression of STAR mRNA]]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [perfluorododecanoic acid inhibits the reaction [Cyclic AMP results in increased expression of STAR protein]]; myricetin promotes the reaction [Cyclic AMP results in increased expression of STAR mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Cyclic AMP co-treated with Verapamil] results in increased expression of STAR protein]; N-(2-(methylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Cyclic AMP co-treated with Verapamil] results in increased expression of STAR protein]; Nifedipine promotes the reaction [Cyclic AMP results in increased expression of STAR mRNA]; perfluorododecanoic acid inhibits the reaction [Cyclic AMP results in increased expression of STAR mRNA]; perfluorododecanoic acid inhibits the reaction [Cyclic AMP results in increased expression of STAR protein]; quercetin pentaacetate promotes the reaction [Cyclic AMP results in increased expression of STAR mRNA]; Quercetin promotes the reaction [Cyclic AMP results in increased expression of STAR mRNA]; Verapamil promotes the reaction [Cyclic AMP results in increased expression of STAR mRNA]; Verapamil promotes the reaction [Cyclic AMP results in increased expression of STAR protein]
Cyclic AMP results in increased expression of STAR mRNA; Cyclic AMP results in increased expression of STAR protein		 CTD PMID:19822634 PMID:20100736 PMID:25576683 PMID:28668616 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992 		JBrowse link
G TAAR1 trace amine associated receptor 1 multiple interactions EXP
ISO		 [Octopamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [phenethylamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [tryptamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Tyramine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP
[3-hydroxy-4-methoxyphenethylamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [3-methoxytyramine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [3-tyramine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [4-chloro-2-(imidazolin-2-yl)isoindoline results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [4-phenyl-1,2,3,4-tetrahydroisoquinoline results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [5-Methoxytryptamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [6-nitroquipazine analog results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Antazoline results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [BE 2254 results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [cirazoline results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Clonidine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [efaroxan results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Fenoldopam results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Guanabenz results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [harman results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Histamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Idazoxan results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Methoxydimethyltryptamines results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [moxonidine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [N-methylquipazine analog results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [O-methyltyramine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Octopamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [phenethylamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Quipazine analog results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [rilmenidine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Tranylcypromine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [tryptamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Tryptamines analog results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP; [Tyramine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP		 CTD PMID:19725810 NCBI chr 6:132,643,312...132,659,182
Ensembl chr 6:132,643,312...132,659,182 		JBrowse link
G TAS1R2 taste 1 receptor member 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of TAS1R2 mRNA] CTD PMID:19414516 NCBI chr 1:18,839,599...18,859,660
Ensembl chr 1:18,839,599...18,859,660 		JBrowse link
G TAX1BP1 Tax1 binding protein 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of TAX1BP1 mRNA] CTD PMID:19414516 NCBI chr 7:27,739,373...27,829,767
Ensembl chr 7:27,739,331...27,844,564 		JBrowse link
G TDO2 tryptophan 2,3-dioxygenase multiple interactions EXP 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of TDO2 mRNA]; [IFNG protein co-treated with [Medroxyprogesterone Acetate co-treated with Cyclic AMP]] results in increased expression of TDO2 mRNA CTD PMID:32781018 NCBI chr 4:155,903,696...155,920,406
Ensembl chr 4:155,854,738...155,920,406 		JBrowse link
G TERT telomerase reverse transcriptase multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of TERT mRNA CTD PMID:33713149 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068 		JBrowse link
G TEX14 testis expressed 14, intercellular bridge forming factor multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of TEX14 mRNA] CTD PMID:19414516 NCBI chr17:58,556,678...58,692,045
Ensembl chr17:58,556,678...58,692,055 		JBrowse link
G TFF1 trefoil factor 1 multiple interactions
increases expression		 EXP CARM1 protein promotes the reaction [Cyclic AMP results in increased expression of TFF1 mRNA]; Cyclic AMP promotes the reaction [CARM1 protein binds to TFF1 promoter] CTD PMID:20360387 NCBI chr21:42,362,282...42,366,535
Ensembl chr21:42,362,282...42,366,535 		JBrowse link
G TGFB3 transforming growth factor beta 3 multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of E2F2 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of FOXM1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of FZD10 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of GLI1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of HES3 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of HOXB1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of INHBE mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of LEF1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of TERT mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of CNTN1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of DLG4 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GABRA2 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GFAP mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIA2 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN2A mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN2B mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of MAP2 protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of RBFOX3 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of RBFOX3 protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of S100B mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of S100B protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SCN2A mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SLC17A6 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SLC17A7 protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SYN mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SYN protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of TUBB3 protein CTD PMID:33713149 NCBI chr14:75,958,097...75,983,011
Ensembl chr14:75,958,097...75,983,011 		JBrowse link
G TMSB15A thymosin beta 15A multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of TMSB15B2 mRNA] CTD PMID:19414516 NCBI chr  X:102,513,682...102,516,739
Ensembl chr  X:102,513,682...102,516,739 		JBrowse link
G TMTC4 transmembrane O-mannosyltransferase targeting cadherins 4 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of TMTC4 mRNA] CTD PMID:19414516 NCBI chr13:100,603,625...100,675,075
Ensembl chr13:100,603,625...100,675,093 		JBrowse link
G TNF tumor necrosis factor decreases expression
multiple interactions		 EXP
ISO		 Cyclic AMP results in decreased expression of TNF protein
Cyclic AMP inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
[[S-Adenosylmethionine inhibits the reaction [Lipopolysaccharides results in increased expression of PDE4B mRNA]] which results in increased abundance of Cyclic AMP] inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]		 CTD PMID:8550079 PMID:21266552 PMID:23566200 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFSF12 TNF superfamily member 12 decreases expression ISO Cyclic AMP results in decreased expression of TNFSF12 mRNA CTD PMID:22117073 NCBI chr17:7,549,058...7,557,881
Ensembl chr17:7,548,508...7,557,890 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 increases expression
multiple interactions		 ISO Cyclic AMP results in increased expression of TRPV4 mRNA; Cyclic AMP results in increased expression of TRPV4 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cyclic AMP results in increased expression of TRPV4 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cyclic AMP results in increased expression of TRPV4 protein]		 CTD PMID:22187434 NCBI chr12:109,783,087...109,833,398
Ensembl chr12:109,783,087...109,833,406 		JBrowse link
G TSHB thyroid stimulating hormone subunit beta multiple interactions
increases abundance		 EXP [Cobalt binds to dipyrido(3,2-a-2',3'-c)phenazine binds to N-(2-hydroxybenzyl)glycine analog] inhibits the reaction [TSHB protein results in increased abundance of Cyclic AMP]; [TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP; bisphenol A inhibits the reaction [[TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP]; Diethylstilbestrol inhibits the reaction [[TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP]; Estradiol inhibits the reaction [[TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP]; resveratrol inhibits the reaction [[TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP]; TSHB protein inhibits the reaction [NCGC 00229600 inhibits the reaction [TSHR protein results in increased abundance of Cyclic AMP]] CTD PMID:19766106 PMID:21072367 PMID:21123444 NCBI chr 1:115,029,826...115,034,309
Ensembl chr 1:115,029,826...115,034,302 		JBrowse link
G TSHR thyroid stimulating hormone receptor multiple interactions
increases abundance		 EXP [TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP; bisphenol A inhibits the reaction [[TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP]; Diethylstilbestrol inhibits the reaction [[TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP]; Estradiol inhibits the reaction [[TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP]; NCGC 00229600 inhibits the reaction [TSHR protein results in increased abundance of Cyclic AMP]; resveratrol inhibits the reaction [[TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP]; TSHB protein inhibits the reaction [NCGC 00229600 inhibits the reaction [TSHR protein results in increased abundance of Cyclic AMP]] CTD PMID:19766106 PMID:21123444 NCBI chr14:80,955,621...81,146,306
Ensembl chr14:80,954,989...81,146,306 		JBrowse link
G TTC6 tetratricopeptide repeat domain 6 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of TTC6 mRNA] CTD PMID:19414516 NCBI chr14:37,595,629...37,842,717
Ensembl chr14:37,595,629...38,041,442 		JBrowse link
G TUBB3 tubulin beta 3 class III multiple interactions EXP [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of TUBB3 protein CTD PMID:33713149 NCBI chr16:89,921,925...89,936,097
Ensembl chr16:89,921,392...89,938,761 		JBrowse link
G UBA5 ubiquitin like modifier activating enzyme 5 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of UBA5 mRNA] CTD PMID:19414516 NCBI chr 3:132,654,430...132,679,794
Ensembl chr 3:132,654,446...132,679,794 		JBrowse link
G VASH1 vasohibin 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of VASH1 mRNA] CTD PMID:19414516 NCBI chr14:76,761,468...76,783,015
Ensembl chr14:76,761,468...76,783,015 		JBrowse link
G VASH2 vasohibin 2 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of VASH2 mRNA] CTD PMID:19414516 NCBI chr 1:212,950,541...212,991,585
Ensembl chr 1:212,950,520...212,992,037 		JBrowse link
G VAT1 vesicle amine transport 1 multiple interactions ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of VAT1 mRNA] CTD PMID:19414516 NCBI chr17:43,014,607...43,022,385
Ensembl chr17:43,014,607...43,025,123 		JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions ISO Cyclic AMP affects the reaction [Norepinephrine results in increased expression of VEGFA mRNA] CTD PMID:10788502 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G VIP vasoactive intestinal peptide multiple interactions
increases abundance		 EXP
ISO		 [VIP protein binds to VIPR2 protein] which results in increased abundance of Cyclic AMP
alpha-hexachlorocyclohexane inhibits the reaction [VIP protein results in increased abundance of Cyclic AMP]; Endrin inhibits the reaction [VIP protein results in increased abundance of Cyclic AMP]; Hexachlorocyclohexane inhibits the reaction [VIP protein results in increased abundance of Cyclic AMP]
VIP protein results in increased abundance of Cyclic AMP; VIP results in increased abundance of Cyclic AMP		 CTD PMID:1657658 PMID:2467674 PMID:7733904 PMID:20732086 NCBI chr 6:152,750,797...152,759,760
Ensembl chr 6:152,750,797...152,759,765 		JBrowse link
G VIPR2 vasoactive intestinal peptide receptor 2 multiple interactions EXP [ADCYAP1 protein binds to VIPR2 protein] which results in increased abundance of Cyclic AMP; [VIP protein binds to VIPR2 protein] which results in increased abundance of Cyclic AMP CTD PMID:7733904 NCBI chr 7:159,028,175...159,144,867
Ensembl chr 7:159,028,175...159,144,867 		JBrowse link
G WNT5A Wnt family member 5A multiple interactions EXP WNT5A protein affects the reaction [[Medroxyprogesterone Acetate results in increased abundance of Cyclic AMP] which results in increased expression of SOD2 mRNA]; WNT5A protein affects the reaction [Medroxyprogesterone Acetate results in increased abundance of Cyclic AMP] CTD PMID:20685861 NCBI chr 3:55,465,715...55,505,263
Ensembl chr 3:55,465,715...55,490,539 		JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 increases abundance ISO ZFP36L2 protein mutant form results in increased abundance of Cyclic AMP CTD PMID:24830504 NCBI chr 2:43,222,402...43,226,606
Ensembl chr 2:43,222,402...43,226,606 		JBrowse link
3',5'-cyclic GMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC4 ATP binding cassette subfamily C member 4 (PEL blood group) increases export
increases transport
multiple interactions		 EXP ABCC4 protein results in increased export of Cyclic GMP
ABCC4 protein results in increased transport of Cyclic GMP
daidzein inhibits the reaction [ABCC4 protein results in increased export of Cyclic GMP]; Dipyridamole inhibits the reaction [ABCC4 protein results in increased transport of Cyclic GMP]; hesperetin inhibits the reaction [ABCC4 protein results in increased export of Cyclic GMP]; naringenin inhibits the reaction [ABCC4 protein results in increased export of Cyclic GMP]; Probenecid inhibits the reaction [ABCC4 protein results in increased transport of Cyclic GMP]; Quercetin inhibits the reaction [ABCC4 protein results in increased export of Cyclic GMP]; resveratrol inhibits the reaction [ABCC4 protein results in increased export of Cyclic GMP]; Silymarin inhibits the reaction [ABCC4 protein results in increased export of Cyclic GMP]		 CTD PMID:11856762 PMID:16156793 NCBI chr13:95,019,835...95,301,451
Ensembl chr13:95,019,835...95,301,475 		JBrowse link
G AGT angiotensinogen multiple interactions
increases abundance		 ISO AGT protein inhibits the reaction [NPPA protein results in increased abundance of Cyclic GMP]; AGT protein modified form inhibits the reaction [Streptozocin results in decreased abundance of Cyclic GMP]; vinpocetine inhibits the reaction [AGT protein inhibits the reaction [NPPA protein results in increased abundance of Cyclic GMP]]
AGT protein modified form results in increased abundance of Cyclic GMP		 CTD PMID:11696475 PMID:28299329 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AGTR2 angiotensin II receptor type 2 multiple interactions ISO [PD 123319 results in decreased activity of AGTR2 protein] inhibits the reaction [Valsartan results in increased abundance of Cyclic GMP] CTD PMID:16982965 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions ISO AKT1 protein inhibits the reaction [Carbon Tetrachloride results in decreased abundance of Cyclic GMP] CTD PMID:12891555 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member multiple interactions EXP ALDH2 protein affects the reaction [Nitroglycerin results in decreased abundance of Cyclic GMP] CTD PMID:17585900 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532 		JBrowse link
G APOE apolipoprotein E decreases abundance ISO APOE gene mutant form results in decreased abundance of Cyclic GMP CTD PMID:11397713 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G BDKRB1 bradykinin receptor B1 multiple interactions ISO [bradykinin, Leu(8)-des-Arg(9)- results in decreased activity of BDKRB1 protein] inhibits the reaction [Valsartan results in increased abundance of Cyclic GMP] CTD PMID:16982965 NCBI chr14:96,256,210...96,264,763
Ensembl chr14:96,256,210...96,268,967 		JBrowse link
G BDKRB2 bradykinin receptor B2 multiple interactions ISO [icatibant results in decreased activity of BDKRB2 protein] inhibits the reaction [Valsartan results in increased abundance of Cyclic GMP] CTD PMID:16982965 NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166 		JBrowse link
G CASP3 caspase 3 multiple interactions ISO Cyclic GMP affects the reaction [Nitric Oxide results in decreased activity of CASP3 protein] CTD PMID:9388267 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CAT catalase multiple interactions ISO CAT protein inhibits the reaction [GCH1 gene mutant form results in increased abundance of Cyclic GMP] CTD PMID:25490417 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCT7 chaperonin containing TCP1 subunit 7 multiple interactions EXP CCT7 protein mutant form inhibits the reaction [S-Nitrosoglutathione results in increased abundance of Cyclic GMP] CTD PMID:24213632 NCBI chr 2:73,234,308...73,253,005
Ensembl chr 2:73,233,420...73,253,021 		JBrowse link
G EDN1 endothelin 1 multiple interactions
increases abundance		 ISO Puromycin Aminonucleoside inhibits the reaction [EDN1 protein results in increased abundance of Cyclic GMP] CTD PMID:12972712 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G EDN3 endothelin 3 multiple interactions
increases abundance		 ISO Puromycin Aminonucleoside promotes the reaction [EDN3 protein results in increased abundance of Cyclic GMP] CTD PMID:12972712 NCBI chr20:59,300,611...59,325,992
Ensembl chr20:59,300,443...59,325,992 		JBrowse link
G EPO erythropoietin multiple interactions ISO EPO protein inhibits the reaction [GCH1 gene mutant form results in increased abundance of Cyclic GMP]; EPO protein inhibits the reaction [HPH1 gene mutant form results in decreased abundance of Cyclic GMP] CTD PMID:25041251 PMID:25490417 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700 		JBrowse link
G GCH1 GTP cyclohydrolase 1 affects abundance
increases abundance
multiple interactions		 ISO GCH1 protein affects the abundance of Cyclic GMP
GCH1 gene mutant form results in increased abundance of Cyclic GMP
CAT protein inhibits the reaction [GCH1 gene mutant form results in increased abundance of Cyclic GMP]; EPO protein inhibits the reaction [GCH1 gene mutant form results in increased abundance of Cyclic GMP]		 CTD PMID:21963838 PMID:25490417 NCBI chr14:54,842,017...54,902,826
Ensembl chr14:54,842,008...54,902,826 		JBrowse link
G GNRH1 gonadotropin releasing hormone 1 multiple interactions ISO [manganese chloride results in increased chemical synthesis of Cyclic GMP] which results in increased secretion of GNRH1 protein CTD PMID:17110411 PMID:17290048 NCBI chr 8:25,419,258...25,425,040
Ensembl chr 8:25,419,258...25,424,654 		JBrowse link
G GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 multiple interactions
increases abundance		 EXP [GUCY1A1 protein binds to GUCY1B1 protein] which results in increased chemical synthesis of Cyclic GMP; GUCY1A1 protein mutant form inhibits the reaction [3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole results in increased abundance of Cyclic GMP]; GUCY1A1 protein mutant form inhibits the reaction [S-Nitrosoglutathione results in increased abundance of Cyclic GMP]
GUCY1A1 gene mutant form results in increased abundance of Cyclic GMP		 CTD PMID:22171090 PMID:24213632 PMID:25373139 NCBI chr 4:155,666,848...155,737,059
Ensembl chr 4:155,666,726...155,737,059 		JBrowse link
G GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 multiple interactions EXP [GUCY1A1 protein binds to GUCY1B1 protein] which results in increased chemical synthesis of Cyclic GMP CTD PMID:22171090 NCBI chr 4:155,759,021...155,807,811
Ensembl chr 4:155,758,992...155,807,811 		JBrowse link
G HMOX2 heme oxygenase 2 affects abundance ISO HMOX2 affects the abundance of Cyclic GMP CTD PMID:16181104 NCBI chr16:4,474,736...4,510,347
Ensembl chr16:4,474,690...4,510,347 		JBrowse link
G IL12RB2 interleukin 12 receptor subunit beta 2 increases expression ISO Cyclic GMP results in increased expression of IL12RB2 mRNA CTD PMID:12451176 NCBI chr 1:67,307,364...67,398,724
Ensembl chr 1:67,307,364...67,398,724 		JBrowse link
G IL1B interleukin 1 beta multiple interactions
increases abundance		 ISO
EXP		 Halothane inhibits the reaction [IL1B protein results in increased abundance of Cyclic GMP]
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased abundance of Cyclic GMP; nitroaspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased abundance of Cyclic GMP]		 CTD PMID:11506125 PMID:14762100 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 multiple interactions
decreases phosphorylation		 EXP Cyclic GMP affects the reaction [NPPA protein alternative form results in decreased phosphorylation of and results in decreased activity of MAP2K1 protein]
Cyclic GMP results in decreased phosphorylation of MAP2K1 protein		 CTD PMID:18225537 NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656 		JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 decreases phosphorylation
multiple interactions		 EXP Cyclic GMP results in decreased phosphorylation of MAP2K2 protein
Cyclic GMP affects the reaction [NPPA protein alternative form results in decreased phosphorylation of and results in decreased activity of MAP2K2 protein]		 CTD PMID:18225537 NCBI chr19:4,090,321...4,124,122
Ensembl chr19:4,090,321...4,124,122 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 increases activity EXP Cyclic GMP analog results in increased activity of MAPK8 protein CTD PMID:11051267 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO [testosterone enanthate results in increased expression of NOS2 mRNA] which results in increased abundance of Cyclic GMP CTD PMID:20463352 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 multiple interactions
increases abundance		 ISO NOS3 protein affects the reaction [Ramipril results in increased abundance of Cyclic GMP]
NOS3 protein results in increased abundance of Cyclic GMP		 CTD PMID:11504159 PMID:16891913 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NPPA natriuretic peptide A multiple interactions
increases abundance		 EXP
ISO		 Cyclic GMP affects the reaction [NPPA protein alternative form results in decreased phosphorylation of and results in decreased activity of MAP2K1 protein]; Cyclic GMP affects the reaction [NPPA protein alternative form results in decreased phosphorylation of and results in decreased activity of MAP2K2 protein]
NPPA protein results in increased abundance of Cyclic GMP
AGT protein inhibits the reaction [NPPA protein results in increased abundance of Cyclic GMP]; carvedilol promotes the reaction [NPPA protein results in increased abundance of Cyclic GMP]; Puromycin Aminonucleoside inhibits the reaction [NPPA protein results in increased abundance of Cyclic GMP]; vinpocetine inhibits the reaction [AGT protein inhibits the reaction [NPPA protein results in increased abundance of Cyclic GMP]]		 CTD PMID:9421401 PMID:11696475 PMID:12022755 PMID:12582005 PMID:12972712 More... NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345 		JBrowse link
G NPPC natriuretic peptide C increases chemical synthesis
increases abundance
multiple interactions		 ISO NPPC protein results in increased chemical synthesis of Cyclic GMP
NPPC protein results in increased abundance of Cyclic GMP
Ammonia inhibits the reaction [NPPC protein results in increased chemical synthesis of Cyclic GMP]; Fluoroacetates inhibits the reaction [NPPC protein results in increased abundance of Cyclic GMP]		 CTD PMID:17629948 PMID:18222015 NCBI chr 2:231,921,809...231,926,396
Ensembl chr 2:231,921,809...231,926,396 		JBrowse link
G PDE10A phosphodiesterase 10A multiple interactions
increases hydrolysis		 EXP Cyclic AMP inhibits the reaction [PDE10A protein results in increased hydrolysis of Cyclic GMP]; Cyclic GMP inhibits the reaction [PDE10A protein results in increased hydrolysis of Cyclic AMP]; Dipyridamole inhibits the reaction [PDE10A protein results in increased hydrolysis of Cyclic GMP] CTD PMID:10373451 NCBI chr 6:165,327,289...165,988,052
Ensembl chr 6:165,327,287...165,988,117 		JBrowse link
G PDE11A phosphodiesterase 11A multiple interactions
increases hydrolysis		 EXP 1-Methyl-3-isobutylxanthine inhibits the reaction [PDE11A protein results in increased hydrolysis of Cyclic GMP]; Dipyridamole inhibits the reaction [PDE11A protein results in increased hydrolysis of Cyclic GMP]; zaprinast inhibits the reaction [PDE11A protein results in increased hydrolysis of Cyclic GMP] CTD PMID:10725373 NCBI chr 2:177,623,244...178,108,339
Ensembl chr 2:177,623,244...178,108,339 		JBrowse link
G PDE1A phosphodiesterase 1A multiple interactions ISO PDE1A protein inhibits the reaction [Nitroglycerin results in increased abundance of Cyclic GMP] CTD PMID:11696475 NCBI chr 2:182,140,041...182,716,797
Ensembl chr 2:182,139,968...182,523,359 		JBrowse link
G PDE5A phosphodiesterase 5A decreases abundance EXP PDE5A protein results in decreased abundance of Cyclic GMP CTD PMID:10422958 NCBI chr 4:119,494,403...119,628,804
Ensembl chr 4:119,494,397...119,628,804 		JBrowse link
G PDE9A phosphodiesterase 9A increases hydrolysis
multiple interactions		 EXP PDE9A protein results in increased hydrolysis of Cyclic GMP
zaprinast inhibits the reaction [PDE9A protein results in increased hydrolysis of Cyclic GMP]		 CTD PMID:9624146 NCBI chr21:42,653,621...42,775,509
Ensembl chr21:42,653,621...42,775,509 		JBrowse link
G POMC proopiomelanocortin affects abundance ISO POMC protein affects the abundance of Cyclic GMP CTD PMID:11193135 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903 		JBrowse link
G PTPN12 protein tyrosine phosphatase non-receptor type 12 increases activity ISO Cyclic GMP results in increased activity of PTPN12 protein CTD PMID:12714323 NCBI chr 7:77,537,295...77,640,069
Ensembl chr 7:77,537,295...77,640,069 		JBrowse link
G STK11 serine/threonine kinase 11 multiple interactions EXP STK11 protein promotes the reaction [Histamine results in increased abundance of Cyclic GMP] CTD PMID:21145922 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431 		JBrowse link
G TNF tumor necrosis factor multiple interactions
decreases abundance		 ISO 7-(2-(4-(4-nitrobenzene)piperazinyl)ethyl)-1,3-dimethylxanthine inhibits the reaction [TNF protein results in decreased abundance of Cyclic GMP]; KMUP 1 inhibits the reaction [TNF protein results in decreased abundance of Cyclic GMP]; zaprinast inhibits the reaction [TNF protein results in decreased abundance of Cyclic GMP] CTD PMID:16754782 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions
increases abundance		 EXP N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [VEGFA protein results in increased abundance of Cyclic GMP] CTD PMID:18575783 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G VIM vimentin multiple interactions ISO VIM protein affects the susceptibility to [Acetylcholine co-treated with Cyclic GMP co-treated with Indomethacin] CTD PMID:11588525 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
G XDH xanthine dehydrogenase multiple interactions ISO [Xanthine co-treated with XDH protein] inhibits the reaction [Nitroprusside results in increased abundance of Cyclic GMP] CTD PMID:17339839 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742 		JBrowse link
3'-CMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase multiple interactions ISO [delta-hexachlorocyclohexane results in decreased activity of CDIPT protein] which results in decreased abundance of Cytidine Monophosphate; [Inositol promotes the reaction [CDIPT protein results in increased metabolism of Cytidine Diphosphate Diglycerides]] which results in increased abundance of Cytidine Monophosphate CTD PMID:2579070 NCBI chr16:29,858,357...29,863,226
Ensembl chr16:29,858,357...29,863,414 		JBrowse link
3'-phospho-5'-adenylyl sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB11 ATP binding cassette subfamily B member 11 multiple interactions EXP [NADP co-treated with Uridine Diphosphate Glucuronic Acid co-treated with Phosphoadenosine Phosphosulfate] promotes the reaction [[Enzymes and Coenzymes results in increased metabolism of diosbulbin B] inhibits the reaction [ABCB11 protein results in increased transport of Taurodeoxycholic Acid]]; [NADP co-treated with Uridine Diphosphate Glucuronic Acid co-treated with Phosphoadenosine Phosphosulfate] promotes the reaction [[Enzymes and Coenzymes results in increased metabolism of saikogenin A analog] inhibits the reaction [ABCB11 protein results in increased transport of Taurodeoxycholic Acid]]; [NADP co-treated with Uridine Diphosphate Glucuronic Acid co-treated with Phosphoadenosine Phosphosulfate] promotes the reaction [[Enzymes and Coenzymes results in increased metabolism of saikogenin A] inhibits the reaction [ABCB11 protein results in increased transport of Taurodeoxycholic Acid]] CTD PMID:35101544 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324 		JBrowse link
G NAT2 N-acetyltransferase 2 multiple interactions EXP [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone] CTD PMID:20545351 NCBI chr 8:18,386,301...18,401,218
Ensembl chr 8:18,391,282...18,401,218 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [NQO1 protein co-treated with NADP co-treated with Phosphoadenosine Phosphosulfate co-treated with SULT1A1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone CTD PMID:20545351 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G P2RY1 purinergic receptor P2Y1 decreases activity EXP Phosphoadenosine Phosphosulfate results in decreased activity of P2RY1 protein CTD PMID:22273509 NCBI chr 3:152,835,131...152,841,439
Ensembl chr 3:152,835,131...152,841,439 		JBrowse link
G SULT1A1 sulfotransferase family 1A member 1 multiple interactions
increases sulfation		 EXP 2,2',3,4,4',5',6-heptabromodiphenyl ether inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]; 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]; [NQO1 protein co-treated with NADP co-treated with Phosphoadenosine Phosphosulfate co-treated with SULT1A1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone; Halogenated Diphenyl Ethers analog inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]; pentabrominated diphenyl ether 100 inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]; Pentachlorophenol inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]; tetrabromobisphenol A inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]; tribromodiphenyl ether 28 inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]
SULT1A1 protein results in increased sulfation of Phosphoadenosine Phosphosulfate		 CTD PMID:11425650 PMID:16601080 PMID:20545351 NCBI chr16:28,605,258...28,623,375
Ensembl chr16:28,605,196...28,610,044 		JBrowse link
G SULT1A2 sulfotransferase family 1A member 2 multiple interactions EXP [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone] CTD PMID:20545351 NCBI chr16:28,591,943...28,597,050
Ensembl chr16:28,591,943...28,597,050 		JBrowse link
G SULT1A3 sulfotransferase family 1A member 3 increases sulfation EXP SULT1A3 protein results in increased sulfation of Phosphoadenosine Phosphosulfate CTD PMID:11425650 NCBI chr16:30,199,255...30,204,310
Ensembl chr16:30,199,228...30,204,310 		JBrowse link
G SULT2A1 sulfotransferase family 2A member 1 multiple interactions EXP [Phosphoadenosine Phosphosulfate co-treated with SULT2A1 protein] affects the sulfation of Ethinyl Estradiol; Celecoxib affects the reaction [[Phosphoadenosine Phosphosulfate co-treated with SULT2A1 protein] affects the sulfation of Ethinyl Estradiol]; SULT2A1 protein affects the metabolism of [Phosphoadenosine Phosphosulfate co-treated with Ethinyl Estradiol] CTD PMID:15483193 NCBI chr19:47,870,467...47,886,315
Ensembl chr19:47,870,467...47,886,315 		JBrowse link
7-methyl-7,8-dihydroguanosine-5'-diphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF4E eukaryotic translation initiation factor 4E affects binding
multiple interactions		 EXP 7-methylguanosine 5'-diphosphate analog binds to EIF4E protein
7-methylguanosine triphosphate inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein]; 7-methylguanosine-5'-monophosphate inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein]; Guanosine analog inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein]; Quinolones inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein]; Sulfonamides inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein]		 CTD PMID:27592390 NCBI chr 4:98,879,276...98,929,133
Ensembl chr 4:98,879,276...98,929,133 		JBrowse link
7-methyl-GTP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF4E eukaryotic translation initiation factor 4E multiple interactions EXP 7-methylguanosine triphosphate inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein]; 7-methylguanosine triphosphate inhibits the reaction [RNA Caps binds to EIF4E protein] CTD PMID:27592390 NCBI chr 4:98,879,276...98,929,133
Ensembl chr 4:98,879,276...98,929,133 		JBrowse link
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
affects binding		 EXP 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one promotes the reaction [EIF4EBP1 protein binds to 7-methylguanosine triphosphate]; Sirolimus promotes the reaction [EIF4EBP1 protein binds to 7-methylguanosine triphosphate] CTD PMID:25940091 NCBI chr 8:38,030,534...38,060,365
Ensembl chr 8:38,030,534...38,060,365 		JBrowse link
G EIF4G1 eukaryotic translation initiation factor 4 gamma 1 multiple interactions
affects binding		 EXP 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one inhibits the reaction [EIF4G1 protein binds to 7-methylguanosine triphosphate]; Sirolimus inhibits the reaction [EIF4G1 protein binds to 7-methylguanosine triphosphate] CTD PMID:25940091 NCBI chr 3:184,314,606...184,335,358
Ensembl chr 3:184,314,495...184,335,358 		JBrowse link
8-(4-chlorophenylthio)-cAMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 multiple interactions
increases expression		 ISO Mevalonic Acid inhibits the reaction [mevastatin inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of ABCA1 protein]]; pitavastatin inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of ABCA1 protein] CTD PMID:16415093 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155 		JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 increases expression ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of ABCB1A mRNA CTD PMID:27160211 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCB11 ATP binding cassette subfamily B member 11 increases expression ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of ABCB11 mRNA CTD PMID:27160211 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 increases expression ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of ABCC2 mRNA CTD PMID:27160211 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) increases expression ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of ABCG2 mRNA CTD PMID:27160211 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 increases phosphorylation ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased phosphorylation of AKT1 protein CTD PMID:20610540 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G BCL2L11 BCL2 like 11 increases expression
increases response to substance		 ISO
EXP		 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of BCL2L11 mRNA; 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of BCL2L11 protein
BCL2L11 protein results in increased susceptibility to 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP		 CTD PMID:14996839 NCBI chr 2:111,120,914...111,168,445
Ensembl chr 2:111,119,378...111,168,444 		JBrowse link
G CASP3 caspase 3 increases activity ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased activity of CASP3 protein CTD PMID:14996839 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CFL1 cofilin 1 decreases phosphorylation ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in decreased phosphorylation of CFL1 protein CTD PMID:20610540 NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026 		JBrowse link
G CFTR CF transmembrane conductance regulator multiple interactions EXP [1-Methyl-3-isobutylxanthine co-treated with 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP] results in increased activity of CFTR protein mutant form; [5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride co-treated with 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP] results in increased activity of CFTR protein mutant form CTD PMID:15163550 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions
increases phosphorylation		 ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased phosphorylation of and results in increased activity of CREB1 protein
8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased phosphorylation of CREB1 protein		 CTD PMID:14741741 PMID:20610540 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 increases expression ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of NFE2L2 mRNA CTD PMID:27160211 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 multiple interactions ISO NR1H2 gene mutant form inhibits the reaction [pitavastatin inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased export of Cholesterol]] CTD PMID:16415093 NCBI chr19:50,376,457...50,383,388
Ensembl chr19:50,329,653...50,383,388 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 multiple interactions ISO NR1H3 gene mutant form inhibits the reaction [pitavastatin inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased export of Cholesterol]] CTD PMID:16415093 NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033 		JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 increases expression ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of NR1I2 mRNA CTD PMID:27160211 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487 		JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 increases expression ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of NR1I3 mRNA CTD PMID:27160211 NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions EXP [Acetylcysteine results in increased susceptibility to 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP] which results in increased cleavage of PARP1 protein CTD PMID:38042493 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G RHOA ras homolog family member A multiple interactions
decreases activity		 ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP inhibits the reaction [RHOA protein binds to RTKN protein]
8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in decreased activity of RHOA protein		 CTD PMID:20610540 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998 		JBrowse link
G RTKN rhotekin multiple interactions ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP inhibits the reaction [RHOA protein binds to RTKN protein] CTD PMID:20610540 NCBI chr 2:74,425,835...74,441,937
Ensembl chr 2:74,425,835...74,442,422 		JBrowse link
G SCNN1A sodium channel epithelial 1 subunit alpha multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP] results in increased activity of [SCNN1A protein binds to SCNN1B protein binds to SCNN1G protein] CTD PMID:15161604 NCBI chr12:6,346,847...6,377,359
Ensembl chr12:6,346,843...6,377,730 		JBrowse link
G SCNN1B sodium channel epithelial 1 subunit beta multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP] results in increased activity of [SCNN1A protein binds to SCNN1B protein binds to SCNN1G protein] CTD PMID:15161604 NCBI chr16:23,278,231...23,381,294
Ensembl chr16:23,278,231...23,381,294 		JBrowse link
G SCNN1G sodium channel epithelial 1 subunit gamma multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP] results in increased activity of [SCNN1A protein binds to SCNN1B protein binds to SCNN1G protein] CTD PMID:15161604 NCBI chr16:23,182,745...23,216,883
Ensembl chr16:23,182,745...23,216,883 		JBrowse link
G SLC10A1 solute carrier family 10 member 1 increases expression ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of SLC10A1 mRNA CTD PMID:27160211 NCBI chr14:69,775,416...69,797,241
Ensembl chr14:69,775,416...69,797,241 		JBrowse link
G SLCO1B3 solute carrier organic anion transporter family member 1B3 increases expression ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of SLCO1B2 mRNA CTD PMID:27160211 NCBI chr12:20,810,705...20,916,911
Ensembl chr12:20,810,702...20,916,911 		JBrowse link
G SNAP25 synaptosome associated protein 25 multiple interactions
affects splicing		 ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-AMP affects the splicing of SNAP25 exon] CTD PMID:22684629 NCBI chr20:10,218,830...10,307,418
Ensembl chr20:10,172,395...10,308,258 		JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 multiple interactions ISO
EXP		 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP promotes the reaction [Capsaicin results in increased activity of TRPV1] CTD PMID:12886029 NCBI chr17:3,565,446...3,609,411
Ensembl chr17:3,565,444...3,609,411 		JBrowse link
G VIP vasoactive intestinal peptide increases expression EXP 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of VIP mRNA CTD PMID:2156696 NCBI chr 6:152,750,797...152,759,760
Ensembl chr 6:152,750,797...152,759,765 		JBrowse link
8-(4-chlorophenylthio)-cGMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX15 arachidonate 15-lipoxygenase increases expression EXP 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased expression of ALOX15 mRNA; 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased expression of ALOX15 protein CTD PMID:16166323 NCBI chr17:4,630,919...4,641,678
Ensembl chr17:4,630,919...4,642,294 		JBrowse link
G ARHGEF17 Rho guanine nucleotide exchange factor 17 multiple interactions EXP 2-methyl-1-((4-methyl-5-isoquinolinyl)sulfonyl)homopiperazine inhibits the reaction [[8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of ARHGEF17 protein]; 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP promotes the reaction [PRKG1 protein binds to and results in increased phosphorylation of ARHGEF17 protein]; [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein co-treated with ARHGEF17 protein] results in increased activity of SRF protein; [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] promotes the reaction [ARHGEF17 protein results in increased activity of RHOA protein]; [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of ARHGEF17 protein; [calyculin A co-treated with Okadaic Acid] inhibits the reaction [2-methyl-1-((4-methyl-5-isoquinolinyl)sulfonyl)homopiperazine inhibits the reaction [[8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of ARHGEF17 protein]]; KT 5823 inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP promotes the reaction [PRKG1 protein binds to and results in increased phosphorylation of ARHGEF17 protein]]; Y 27632 inhibits the reaction [[8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of ARHGEF17 protein] CTD PMID:23195829 NCBI chr11:73,308,276...73,369,388
Ensembl chr11:73,308,276...73,369,388 		JBrowse link
G CEBPB CCAAT enhancer binding protein beta increases expression
multiple interactions		 ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased expression of CEBPB protein
8-(4-chlorophenylthio)guanosine 3',5'-cyclic monophosphorothioate inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased expression of CEBPB protein]		 CTD PMID:20471953 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668 		JBrowse link
G FABP4 fatty acid binding protein 4 increases expression
multiple interactions		 ISO 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased expression of FABP4 protein
8-(4-chlorophenylthio)guanosine 3',5'-cyclic monophosphorothioate inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased expression of FABP4 protein]		 CTD PMID:20471953 NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236 		JBrowse link
G NPPA natriuretic peptide A multiple interactions ISO [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein alternative form] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA] CTD PMID:11799084 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions
increases expression		 ISO 8-(4-chlorophenylthio)guanosine 3',5'-cyclic monophosphorothioate inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased expression of PPARG protein] CTD PMID:20471953 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 multiple interactions
decreases expression
increases activity		 EXP
ISO		 2-methyl-1-((4-methyl-5-isoquinolinyl)sulfonyl)homopiperazine inhibits the reaction [[8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of ARHGEF17 protein]; 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP promotes the reaction [PRKG1 protein binds to and results in increased phosphorylation of ARHGEF17 protein]; [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein co-treated with ARHGEF17 protein] results in increased activity of SRF protein; [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] promotes the reaction [ARHGEF17 protein results in increased activity of RHOA protein]; [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of ARHGEF17 protein; [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of RHOA protein; [calyculin A co-treated with Okadaic Acid] inhibits the reaction [2-methyl-1-((4-methyl-5-isoquinolinyl)sulfonyl)homopiperazine inhibits the reaction [[8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of ARHGEF17 protein]]; KT 5823 inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP promotes the reaction [PRKG1 protein binds to and results in increased phosphorylation of ARHGEF17 protein]]; KT 5823 inhibits the reaction [[8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of RHOA protein]; Y 27632 inhibits the reaction [[8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of ARHGEF17 protein]
8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in decreased expression of PRKG1 protein; 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in decreased expression of PRKG1 protein alternative form
8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased activity of PRKG1 protein
[8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein alternative form] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]		 CTD PMID:9366573 PMID:11799084 PMID:23195829 NCBI chr10:50,990,888...52,298,350
Ensembl chr10:50,990,888...52,298,423 		JBrowse link
G RHOA ras homolog family member A multiple interactions EXP [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] promotes the reaction [ARHGEF17 protein results in increased activity of RHOA protein]; [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of RHOA protein; KT 5823 inhibits the reaction [[8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of RHOA protein] CTD PMID:23195829 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998 		JBrowse link
G SCNN1A sodium channel epithelial 1 subunit alpha multiple interactions EXP 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased activity of [SCNN1A binds to SCNN1B binds to SCNN1G binds to SCNN1D] CTD PMID:19359370 NCBI chr12:6,346,847...6,377,359
Ensembl chr12:6,346,843...6,377,730 		JBrowse link
G SCNN1B sodium channel epithelial 1 subunit beta multiple interactions EXP 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased activity of [SCNN1A binds to SCNN1B binds to SCNN1G binds to SCNN1D] CTD PMID:19359370 NCBI chr16:23,278,231...23,381,294
Ensembl chr16:23,278,231...23,381,294 		JBrowse link
G SCNN1D sodium channel epithelial 1 subunit delta multiple interactions EXP 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased activity of [SCNN1A binds to SCNN1B binds to SCNN1G binds to SCNN1D] CTD PMID:19359370 NCBI chr 1:1,280,436...1,292,025
Ensembl chr 1:1,280,436...1,292,029 		JBrowse link
G SCNN1G sodium channel epithelial 1 subunit gamma multiple interactions EXP 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased activity of [SCNN1A binds to SCNN1B binds to SCNN1G binds to SCNN1D] CTD PMID:19359370 NCBI chr16:23,182,745...23,216,883
Ensembl chr16:23,182,745...23,216,883 		JBrowse link
G SRF serum response factor multiple interactions EXP [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein co-treated with ARHGEF17 protein] results in increased activity of SRF protein CTD PMID:23195829 NCBI chr 6:43,171,269...43,181,506
Ensembl chr 6:43,171,269...43,181,506 		JBrowse link
G VASP vasodilator stimulated phosphoprotein increases phosphorylation
decreases phosphorylation		 EXP
ISO		 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased phosphorylation of VASP protein
8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in decreased phosphorylation of VASP protein		 CTD PMID:11799084 PMID:16166323 NCBI chr19:45,507,479...45,526,983
Ensembl chr19:45,506,579...45,526,989 		JBrowse link
8-Br-cAMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 increases expression EXP
ISO		 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ABCA1 protein CTD PMID:17478430 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155 		JBrowse link
G ABCB11 ATP binding cassette subfamily B member 11 multiple interactions ISO 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCB11 mRNA] CTD PMID:27743861 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ABCC1 mRNA CTD PMID:22079614 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 multiple interactions ISO 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA] CTD PMID:27743861 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCD2 ATP binding cassette subfamily D member 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ABCD2 mRNA CTD PMID:22079614 NCBI chr12:39,531,025...39,619,803
Ensembl chr12:39,550,033...39,619,803 		JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ABCG1 mRNA CTD PMID:22079614 NCBI chr21:42,199,689...42,297,244
Ensembl chr21:42,199,689...42,297,244 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) multiple interactions EXP 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [anandamide results in decreased expression of ABCG2 mRNA] CTD PMID:30610963 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628 		JBrowse link
G ABLIM1 actin binding LIM protein 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ABLIM1 mRNA CTD PMID:22079614 NCBI chr10:114,431,110...114,801,373
Ensembl chr10:114,431,112...114,768,061 		JBrowse link
G ABLIM2 actin binding LIM protein family member 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ABLIM2 mRNA CTD PMID:22079614 NCBI chr 4:7,965,327...8,158,813
Ensembl chr 4:7,965,310...8,158,832 		JBrowse link
G ACAT2 acetyl-CoA acetyltransferase 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ACAT2 mRNA CTD PMID:22079614 NCBI chr 6:159,762,045...159,779,112
Ensembl chr 6:159,762,045...159,779,112 		JBrowse link
G ACE2 angiotensin converting enzyme 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ACE2 mRNA CTD PMID:22079614 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236 		JBrowse link
G ACP3 acid phosphatase 3 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ACP3 mRNA CTD PMID:22079614 NCBI chr 3:132,317,407...132,368,302
Ensembl chr 3:132,317,369...132,368,302 		JBrowse link
G ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif 6 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ADAMTS6 mRNA CTD PMID:20147733 PMID:22079614 NCBI chr 5:65,148,738...65,481,920
Ensembl chr 5:65,148,738...65,481,920 		JBrowse link
G ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif 8 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ADAMTS8 mRNA CTD PMID:22079614 NCBI chr11:130,404,923...130,428,609
Ensembl chr11:130,404,923...130,428,609 		JBrowse link
G ADCY7 adenylate cyclase 7 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ADCY7 mRNA CTD PMID:22079614 NCBI chr16:50,244,699...50,318,135
Ensembl chr16:50,246,137...50,318,135 		JBrowse link
G ADGRD1 adhesion G protein-coupled receptor D1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ADGRD1 mRNA CTD PMID:22079614 NCBI chr12:130,953,907...131,141,469
Ensembl chr12:130,953,907...131,141,469 		JBrowse link
G ADGRF5 adhesion G protein-coupled receptor F5 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADGRF5 mRNA CTD PMID:16997883 NCBI chr 6:46,852,522...46,954,939
Ensembl chr 6:46,852,522...46,954,943 		JBrowse link
G ADGRG1 adhesion G protein-coupled receptor G1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ADGRG1 mRNA CTD PMID:22079614 NCBI chr16:57,619,738...57,665,567
Ensembl chr16:57,610,652...57,665,580 		JBrowse link
G ADGRG2 adhesion G protein-coupled receptor G2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ADGRG2 mRNA CTD PMID:22079614 NCBI chr  X:18,989,307...19,122,956
Ensembl chr  X:18,989,307...19,122,637 		JBrowse link
G ADRA2A adrenoceptor alpha 2A decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ADRA2A mRNA CTD PMID:22079614 NCBI chr10:111,077,029...111,080,907
Ensembl chr10:111,077,029...111,080,907 		JBrowse link
G AGR2 anterior gradient 2, protein disulphide isomerase family member multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of AGR2 mRNA CTD PMID:16997883 NCBI chr 7:16,791,811...16,804,999
Ensembl chr 7:16,791,811...16,833,433 		JBrowse link
G AGT angiotensinogen decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of AGT mRNA CTD PMID:22079614 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AGTR1 angiotensin II receptor type 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of AGTR1 mRNA CTD PMID:22079614 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G AHR aryl hydrocarbon receptor increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of AHR mRNA CTD PMID:22079614 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G AIFM1 apoptosis inducing factor mitochondria associated 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of AIFM1 mRNA CTD PMID:22079614 NCBI chr  X:130,129,362...130,165,841
Ensembl chr  X:130,124,666...130,165,879 		JBrowse link
G AKAP7 A-kinase anchoring protein 7 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of AKAP7 mRNA CTD PMID:16997883 NCBI chr 6:131,125,627...131,283,532
Ensembl chr 6:131,135,467...131,283,535 		JBrowse link
G AKAP9 A-kinase anchoring protein 9 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of AKAP9 mRNA CTD PMID:22079614 NCBI chr 7:91,940,862...92,110,673
Ensembl chr 7:91,940,840...92,110,673 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of AKT1 mRNA CTD PMID:22079614 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G ALB albumin decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ALB mRNA CTD PMID:22079614 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ALDH1A1 mRNA CTD PMID:22079614 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442 		JBrowse link
G ANGPT1 angiopoietin 1 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ANGPT1 mRNA CTD PMID:16997883 NCBI chr 8:107,249,482...107,497,918
Ensembl chr 8:107,249,482...107,498,055 		JBrowse link
G ANGPTL1 angiopoietin like 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ANGPTL1 mRNA CTD PMID:22079614 NCBI chr 1:178,849,535...178,871,077
Ensembl chr 1:178,849,535...178,871,077 		JBrowse link
G ANKH ANKH inorganic pyrophosphate transport regulator increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ANKH mRNA CTD PMID:20147733 NCBI chr 5:14,704,800...14,871,778
Ensembl chr 5:14,704,800...14,871,778 		JBrowse link
G ANKRD20A2P ankyrin repeat domain 20 family member A2, pseudogene decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ANKRD20A2P mRNA CTD PMID:22079614 NCBI chr 9:40,222,102...40,282,358
Ensembl chr 9:40,223,397...40,292,345 		JBrowse link
G ANXA8 annexin A8 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of ANXA8 mRNA CTD PMID:16997883 NCBI chr10:47,467,993...47,991,796
Ensembl chr10:47,460,162...47,484,158 		JBrowse link
G AOPEP aminopeptidase O (putative) decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of AOPEP mRNA CTD PMID:22079614 NCBI chr 9:94,726,699...95,150,224
Ensembl chr 9:94,726,604...95,151,793 		JBrowse link
G APAF1 apoptotic peptidase activating factor 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of APAF1 mRNA CTD PMID:22079614 NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,290...98,735,433 		JBrowse link
G APBB1IP amyloid beta precursor protein binding family B member 1 interacting protein increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of APBB1IP mRNA CTD PMID:22079614 NCBI chr10:26,438,341...26,567,803
Ensembl chr10:26,438,341...26,567,803 		JBrowse link
G APC APC regulator of WNT signaling pathway decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of APC mRNA CTD PMID:22079614 NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,518...112,846,239 		JBrowse link
G APCDD1 APC down-regulated 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of APCDD1 mRNA CTD PMID:22079614 NCBI chr18:10,454,635...10,489,949
Ensembl chr18:10,454,635...10,489,949 		JBrowse link
G AR androgen receptor decreases expression
multiple interactions		 EXP
ISO		 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of AR mRNA
[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of AR mRNA; naphthol AS-E phosphate inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of AR mRNA]		 CTD PMID:18467523 PMID:22079614 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619 		JBrowse link
G AREG amphiregulin increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of AREG mRNA CTD PMID:20147733 PMID:22079614 NCBI chr 4:74,445,136...74,455,005
Ensembl chr 4:74,445,136...74,455,005 		JBrowse link
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ARHGEF2 mRNA CTD PMID:22079614 NCBI chr 1:155,946,854...155,979,617
Ensembl chr 1:155,946,851...156,007,070 		JBrowse link
G ARHGEF4 Rho guanine nucleotide exchange factor 4 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ARHGEF4 mRNA CTD PMID:22079614 NCBI chr 2:130,836,914...131,047,253
Ensembl chr 2:130,836,914...131,047,263 		JBrowse link
G ARID5B AT-rich interaction domain 5B decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ARID5B mRNA CTD PMID:22079614 NCBI chr10:61,901,699...62,096,944
Ensembl chr10:61,901,684...62,096,944 		JBrowse link
G ARMCX3 armadillo repeat containing X-linked 3 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ARMCX3 mRNA CTD PMID:22079614 NCBI chr  X:101,623,151...101,627,843
Ensembl chr  X:101,622,797...101,627,843 		JBrowse link
G ARMCX4 armadillo repeat containing X-linked 4 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ARMCX4 mRNA CTD PMID:22079614 NCBI chr  X:101,418,278...101,535,988
Ensembl chr  X:101,418,287...101,533,459 		JBrowse link
G ASNS asparagine synthetase (glutamine-hydrolyzing) increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ASNS mRNA CTD PMID:22079614 NCBI chr 7:97,851,677...97,928,441
Ensembl chr 7:97,851,677...97,872,542 		JBrowse link
G ATP4A ATPase H+/K+ transporting subunit alpha increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ATP4A mRNA CTD PMID:22079614 NCBI chr19:35,550,031...35,563,658
Ensembl chr19:35,550,031...35,563,658 		JBrowse link
G AVPI1 arginine vasopressin induced 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of AVPI1 mRNA CTD PMID:22079614 NCBI chr10:97,677,424...97,687,241
Ensembl chr10:97,677,424...97,687,241 		JBrowse link
G B4GALNT3 beta-1,4-N-acetyl-galactosaminyltransferase 3 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of B4GALNT3 mRNA CTD PMID:22079614 NCBI chr12:459,939...563,509
Ensembl chr12:459,939...563,509 		JBrowse link
G BANK1 B cell scaffold protein with ankyrin repeats 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of BANK1 mRNA CTD PMID:22079614 NCBI chr 4:101,790,730...102,074,812
Ensembl chr 4:101,411,286...102,074,812 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of BAX
[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of BAX protein		 CTD PMID:11802967 PMID:16709600 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCAT1 branched chain amino acid transaminase 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of BCAT1 mRNA CTD PMID:22079614 NCBI chr12:24,810,024...24,949,340
Ensembl chr12:24,810,024...24,949,101 		JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of BCL2 CTD PMID:11802967 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L11 BCL2 like 11 multiple interactions EXP [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of BCL2L11 protein CTD PMID:16709600 NCBI chr 2:111,120,914...111,168,445
Ensembl chr 2:111,119,378...111,168,444 		JBrowse link
G BDKRB1 bradykinin receptor B1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of BDKRB1 mRNA CTD PMID:20147733 NCBI chr14:96,256,210...96,264,763
Ensembl chr14:96,256,210...96,268,967 		JBrowse link
G BDKRB2 bradykinin receptor B2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of BDKRB2 mRNA CTD PMID:20147733 NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166 		JBrowse link
G BMP4 bone morphogenetic protein 4 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of BMP4 mRNA CTD PMID:22079614 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761 		JBrowse link
G BMP6 bone morphogenetic protein 6 decreases expression
increases expression		 EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of BMP6 mRNA
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of BMP6 mRNA		 CTD PMID:20147733 PMID:22079614 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728 		JBrowse link
G BRINP1 BMP/retinoic acid inducible neural specific 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of BRINP1 mRNA CTD PMID:20147733 NCBI chr 9:119,166,629...119,369,435
Ensembl chr 9:119,153,458...119,369,435 		JBrowse link
G BTBD9 BTB domain containing 9 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of BTBD9 mRNA CTD PMID:22079614 NCBI chr 6:38,168,451...38,639,929
Ensembl chr 6:38,168,451...38,640,148 		JBrowse link
G CABLES1 Cdk5 and Abl enzyme substrate 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CABLES1 mRNA CTD PMID:22079614 NCBI chr18:23,134,564...23,260,470
Ensembl chr18:23,134,564...23,260,470 		JBrowse link
G CABP7 calcium binding protein 7 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CABP7 mRNA CTD PMID:22079614 NCBI chr22:29,720,003...29,731,833
Ensembl chr22:29,720,003...29,731,833 		JBrowse link
G CADM1 cell adhesion molecule 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CADM1 mRNA CTD PMID:22079614 NCBI chr11:115,169,236...115,504,415
Ensembl chr11:115,169,218...115,504,957 		JBrowse link
G CADM2 cell adhesion molecule 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CADM2 mRNA CTD PMID:22079614 NCBI chr 3:84,958,989...86,074,429
Ensembl chr 3:84,958,989...86,074,429 		JBrowse link
G CALN1 calneuron 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CALN1 mRNA CTD PMID:22079614 NCBI chr 7:71,779,491...72,504,279
Ensembl chr 7:71,779,491...72,447,151 		JBrowse link
G CALR calreticulin increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CALR mRNA CTD PMID:22079614 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489 		JBrowse link
G CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CAMK2N1 mRNA CTD PMID:22079614 NCBI chr 1:20,482,391...20,486,210
Ensembl chr 1:20,482,391...20,486,210 		JBrowse link
G CAPN15 calpain 15 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CAPN15 mRNA CTD PMID:22079614 NCBI chr16:527,712...554,636
Ensembl chr16:527,712...554,636 		JBrowse link
G CAPN2 calpain 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CAPN2 mRNA CTD PMID:22079614 NCBI chr 1:223,701,597...223,776,018
Ensembl chr 1:223,701,593...223,776,018 		JBrowse link
G CAPN6 calpain 6 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CAPN6 mRNA CTD PMID:22079614 NCBI chr  X:111,245,099...111,270,483
Ensembl chr  X:111,245,099...111,270,483 		JBrowse link
G CARD14 caspase recruitment domain family member 14 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CARD14 mRNA CTD PMID:22079614 NCBI chr17:80,170,030...80,209,331
Ensembl chr17:80,169,992...80,216,073 		JBrowse link
G CARS1 cysteinyl-tRNA synthetase 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CARS1 mRNA CTD PMID:22079614 NCBI chr11:3,000,929...3,057,423
Ensembl chr11:3,000,922...3,057,613 		JBrowse link
G CASP3 caspase 3 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CASP3 mRNA CTD PMID:22079614 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP9 caspase 9 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CASP9 mRNA CTD PMID:22079614 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAT catalase multiple interactions EXP [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CAT mRNA CTD PMID:16709600 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CBR4 carbonyl reductase 4 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CBR4 mRNA CTD PMID:22079614 NCBI chr 4:168,894,486...169,010,255
Ensembl chr 4:168,863,770...169,010,275 		JBrowse link
G CCDC170 coiled-coil domain containing 170 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CCDC170 mRNA CTD PMID:22079614 NCBI chr 6:151,494,017...151,621,193
Ensembl chr 6:151,494,017...151,621,193 		JBrowse link
G CCDC3 coiled-coil domain containing 3 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CCDC3 mRNA CTD PMID:22079614 NCBI chr10:12,896,625...13,099,989
Ensembl chr10:12,896,625...13,099,652 		JBrowse link
G CCDC80 coiled-coil domain containing 80 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CCDC80 mRNA CTD PMID:22079614 NCBI chr 3:112,596,797...112,641,143
Ensembl chr 3:112,596,797...112,649,530 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions
increases expression		 EXP
ISO		 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]]; 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [TNF protein results in increased secretion of CCL2 protein]]; [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of CCL2 mRNA
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CCL2 protein		 CTD PMID:11230753 PMID:16997883 PMID:20940016 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 multiple interactions ISO 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Reactive Oxygen Species results in increased expression of CCL5 mRNA]; 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA] CTD PMID:10495789 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCN3 cellular communication network factor 3 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CCN3 mRNA CTD PMID:22079614 NCBI chr 8:119,416,446...119,424,434
Ensembl chr 8:119,416,446...119,424,434 		JBrowse link
G CCN6 cellular communication network factor 6 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CCN6 mRNA CTD PMID:22079614 NCBI chr 6:112,052,813...112,069,686
Ensembl chr 6:112,054,075...112,069,686 		JBrowse link
G CCNA1 cyclin A1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CCNA1 mRNA CTD PMID:22079614 NCBI chr13:36,431,517...36,442,870
Ensembl chr13:36,431,520...36,442,870 		JBrowse link
G CCND2 cyclin D2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CCND2 mRNA CTD PMID:22079614 NCBI chr12:4,273,762...4,305,353
Ensembl chr12:4,269,771...4,305,353 		JBrowse link
G CD244 CD244 molecule increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CD244 mRNA CTD PMID:22079614 NCBI chr 1:160,830,160...160,862,887
Ensembl chr 1:160,830,160...160,862,887 		JBrowse link
G CD74 CD74 molecule increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CD74 mRNA CTD PMID:22079614 NCBI chr 5:150,401,639...150,412,910
Ensembl chr 5:150,401,637...150,412,969 		JBrowse link
G CD9 CD9 molecule increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CD9 mRNA CTD PMID:22079614 NCBI chr12:6,199,946...6,238,266
Ensembl chr12:6,199,715...6,238,271 		JBrowse link
G CDC42 cell division cycle 42 multiple interactions ISO 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [CRH protein inhibits the reaction [CGB3 protein results in increased chemical synthesis of Testosterone]]; 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Testosterone]] CTD PMID:2153673 NCBI chr 1:22,052,709...22,101,360
Ensembl chr 1:22,052,627...22,101,360 		JBrowse link
G CDH1 cadherin 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CDH1 protein CTD PMID:32028606 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G CDH22 cadherin 22 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CDH22 mRNA CTD PMID:22079614 NCBI chr20:46,173,739...46,308,498
Ensembl chr20:46,173,739...46,308,498 		JBrowse link
G CDH4 cadherin 4 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CDH4 mRNA CTD PMID:22079614 NCBI chr20:61,252,261...61,940,617
Ensembl chr20:61,252,261...61,940,617 		JBrowse link
G CDH6 cadherin 6 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CDH6 mRNA CTD PMID:22079614 NCBI chr 5:31,193,686...31,329,146
Ensembl chr 5:31,193,686...31,329,146 		JBrowse link
G CDK2 cyclin dependent kinase 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CDK2 mRNA CTD PMID:22079614 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CDKN1A mRNA CTD PMID:22079614 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G CDON cell adhesion associated, oncogene regulated increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CDON mRNA CTD PMID:20147733 NCBI chr11:125,956,821...126,063,352
Ensembl chr11:125,955,796...126,063,335 		JBrowse link
G CDX1 caudal type homeobox 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CDX1 mRNA CTD PMID:22079614 NCBI chr 5:150,166,778...150,184,558
Ensembl chr 5:150,166,778...150,184,558 		JBrowse link
G CEACAM6 CEA cell adhesion molecule 6 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CEACAM6 mRNA CTD PMID:16997883 NCBI chr19:41,755,530...41,772,211
Ensembl chr19:41,750,977...41,772,211 		JBrowse link
G CEBPG CCAAT enhancer binding protein gamma increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CEBPG mRNA CTD PMID:22079614 NCBI chr19:33,373,709...33,382,686
Ensembl chr19:33,373,685...33,382,686 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator multiple interactions EXP [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CFLAR protein alternative form CTD PMID:16709600 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687 		JBrowse link
G CGA glycoprotein hormones, alpha polypeptide increases expression ISO
EXP		 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CGA mRNA CTD PMID:8404651 PMID:21467749 PMID:22079614 NCBI chr 6:87,085,498...87,095,106
Ensembl chr 6:87,085,498...87,095,106 		JBrowse link
G CGN cingulin increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CGN mRNA CTD PMID:22079614 NCBI chr 1:151,510,170...151,538,692
Ensembl chr 1:151,510,510...151,538,692 		JBrowse link
G CHN1 chimerin 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CHN1 mRNA CTD PMID:22079614 NCBI chr 2:174,798,809...175,005,381
Ensembl chr 2:174,798,809...175,005,381 		JBrowse link
G CHP1 calcineurin like EF-hand protein 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CHP1 mRNA CTD PMID:22079614 NCBI chr15:41,231,268...41,281,887
Ensembl chr15:41,230,839...41,281,887 		JBrowse link
G CIDEA cell death inducing DFFA like effector a increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CIDEA mRNA CTD PMID:22079614 NCBI chr18:12,254,361...12,277,595
Ensembl chr18:12,254,361...12,277,595 		JBrowse link
G CIDEC cell death inducing DFFA like effector c increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CIDEC protein CTD PMID:21097823 NCBI chr 3:9,866,710...9,880,253
Ensembl chr 3:9,866,711...9,880,255 		JBrowse link
G CKMT2 creatine kinase, mitochondrial 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CKMT2 mRNA CTD PMID:22079614 NCBI chr 5:81,233,322...81,266,398
Ensembl chr 5:81,233,320...81,266,398 		JBrowse link
G CLDN1 claudin 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CLDN1 mRNA CTD PMID:22079614 NCBI chr 3:190,305,707...190,322,446
Ensembl chr 3:190,305,707...190,322,446 		JBrowse link
G CLDN5 claudin 5 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CLDN5 mRNA CTD PMID:20711499 NCBI chr22:19,523,024...19,525,337
Ensembl chr22:19,523,024...19,527,545 		JBrowse link
G CLGN calmegin increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CLGN mRNA CTD PMID:20147733 PMID:22079614 NCBI chr 4:140,388,453...140,427,648
Ensembl chr 4:140,388,453...140,427,661 		JBrowse link
G CLIC3 chloride intracellular channel 3 multiple interactions
increases expression		 EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CLIC3 mRNA
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CLIC3 mRNA		 CTD PMID:16997883 PMID:22079614 NCBI chr 9:136,994,608...136,996,568
Ensembl chr 9:136,994,608...136,996,568 		JBrowse link
G CMKLR1 chemerin chemokine-like receptor 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CMKLR1 mRNA CTD PMID:20147733 NCBI chr12:108,288,046...108,339,311
Ensembl chr12:108,288,044...108,339,317 		JBrowse link
G CNIH3 cornichon family AMPA receptor auxiliary protein 3 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CNIH3 mRNA CTD PMID:22079614 NCBI chr 1:224,434,640...224,740,554
Ensembl chr 1:224,434,660...224,740,554 		JBrowse link
G CNR1 cannabinoid receptor 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CNR1 mRNA CTD PMID:22079614 NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347 		JBrowse link
G COL15A1 collagen type XV alpha 1 chain multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of COL15A1 mRNA CTD PMID:16997883 NCBI chr 9:98,943,907...99,070,787
Ensembl chr 9:98,943,179...99,070,787 		JBrowse link
G COL4A4 collagen type IV alpha 4 chain decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of COL4A4 mRNA CTD PMID:22079614 NCBI chr 2:226,967,360...227,164,488
Ensembl chr 2:227,002,714...227,164,453 		JBrowse link
G COL4A6 collagen type IV alpha 6 chain multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of COL4A6 mRNA CTD PMID:16997883 NCBI chr  X:108,155,614...108,439,458
Ensembl chr  X:108,155,607...108,439,497 		JBrowse link
G COL6A3 collagen type VI alpha 3 chain decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of COL6A3 mRNA CTD PMID:22079614 NCBI chr 2:237,324,018...237,414,164
Ensembl chr 2:237,324,003...237,414,328 		JBrowse link
G COL7A1 collagen type VII alpha 1 chain multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of COL7A1 mRNA CTD PMID:16997883 NCBI chr 3:48,564,073...48,595,329
Ensembl chr 3:48,564,073...48,595,329 		JBrowse link
G COLEC12 collectin subfamily member 12 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of COLEC12 mRNA CTD PMID:22079614 NCBI chr18:316,737...500,701
Ensembl chr18:316,737...500,722 		JBrowse link
G CORO2A coronin 2A decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CORO2A mRNA CTD PMID:22079614 NCBI chr 9:98,120,975...98,192,637
Ensembl chr 9:98,120,975...98,192,637 		JBrowse link
G CPM carboxypeptidase M decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CPM mRNA CTD PMID:22079614 NCBI chr12:68,842,197...68,963,469
Ensembl chr12:68,842,197...68,971,570 		JBrowse link
G CPO carboxypeptidase O increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CPO mRNA CTD PMID:22079614 NCBI chr 2:206,939,518...206,969,474
Ensembl chr 2:206,939,518...206,969,474 		JBrowse link
G CRADD CASP2 and RIPK1 domain containing adaptor with death domain increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CRADD mRNA CTD PMID:22079614 NCBI chr12:93,677,375...93,894,840
Ensembl chr12:93,677,375...93,894,840 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions ISO [monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of CREB1 protein CTD PMID:18467523 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988 		JBrowse link
G CRH corticotropin releasing hormone multiple interactions ISO 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [CRH protein inhibits the reaction [CGB3 protein results in increased chemical synthesis of Testosterone]] CTD PMID:2153673 NCBI chr 8:66,176,376...66,178,464
Ensembl chr 8:66,176,376...66,178,464 		JBrowse link
G CRHBP corticotropin releasing hormone binding protein decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CRHBP mRNA CTD PMID:22079614 NCBI chr 5:76,953,045...76,981,159
Ensembl chr 5:76,953,045...76,981,158 		JBrowse link
G CST6 cystatin E/M multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of CST6 mRNA CTD PMID:16997883 NCBI chr11:66,012,008...66,013,505
Ensembl chr11:66,012,008...66,013,505 		JBrowse link
G CTAGE1 cutaneous T cell lymphoma-associated antigen 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CTAGE1 mRNA CTD PMID:22079614 NCBI chr18:22,413,599...22,417,915
Ensembl chr18:22,413,599...22,417,915 		JBrowse link
G CTNNA2 catenin alpha 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CTNNA2 mRNA CTD PMID:22079614 NCBI chr 2:79,185,377...80,648,780
Ensembl chr 2:79,185,231...80,648,861 		JBrowse link
G CTTNBP2 cortactin binding protein 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CTTNBP2 mRNA CTD PMID:22079614 NCBI chr 7:117,710,651...117,873,441
Ensembl chr 7:117,710,651...117,874,139 		JBrowse link
G CUX2 cut like homeobox 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CUX2 mRNA CTD PMID:22079614 NCBI chr12:111,034,165...111,350,554
Ensembl chr12:111,034,165...111,350,554 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CX3CL1 mRNA CTD PMID:22079614 NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CXCL10 mRNA CTD PMID:22079614 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 decreases expression
increases expression		 ISO
EXP		 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CXCL12 mRNA
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CXCL12 mRNA		 CTD PMID:20711499 PMID:22079614 NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions
increases expression		 EXP daidzein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CXCL8 mRNA]; Estradiol inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CXCL8 mRNA]; Genistein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CXCL8 mRNA] CTD PMID:21056929 PMID:22079614 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYCS cytochrome c, somatic decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CYCS mRNA CTD PMID:22079614 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 multiple interactions
increases expression
increases activity		 ISO
EXP		 2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 mRNA]; 2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 protein]; 2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 mRNA]]; 2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 protein]]; [NR5A1 protein co-treated with 20-hydroxycholesterol co-treated with Tretinoin co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP11A1 mRNA; [NR5A1 protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP11A1 mRNA; Hydrocarbons, Chlorinated inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 protein]; THRA mutant form inhibits the reaction [2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 mRNA]]; Triiodothyronine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 mRNA]; Triiodothyronine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 protein]
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 mRNA; 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 protein
bifenthrin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 mRNA]; Mitotane inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 mRNA]
8-Bromo Cyclic Adenosine Monophosphate results in increased activity of CYP11A1 protein
2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of CYP11A1 protein]		 CTD PMID:20147733 PMID:21126571 PMID:21610156 PMID:21664964 PMID:21726595 More... NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646 		JBrowse link
G CYP11B1 cytochrome P450 family 11 subfamily B member 1 multiple interactions
increases expression		 EXP bifenthrin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11B1 mRNA]; Mitotane affects the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11B1 mRNA] CTD PMID:22079614 PMID:22172629 PMID:22546480 PMID:34896276 NCBI chr 8:142,872,357...142,879,825
Ensembl chr 8:142,872,356...142,879,846 		JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11B2 mRNA CTD PMID:22079614 PMID:34896276 NCBI chr 8:142,910,559...142,917,843
Ensembl chr 8:142,910,559...142,917,843 		JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 multiple interactions
increases expression		 EXP
ISO		 [4-nitro-3-phenylphenol co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in decreased expression of CYP17A1 protein; bifenthrin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 mRNA]; Mitotane inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 mRNA]
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 mRNA; 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 protein
2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 mRNA]; 2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 protein]; 2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 mRNA]]; 2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 protein]]; [NR5A1 protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP17A1 mRNA; THRA mutant form inhibits the reaction [2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 mRNA]]; Triiodothyronine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 mRNA]; Triiodothyronine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 protein]		 CTD PMID:18336853 PMID:21610156 PMID:21726595 PMID:22079614 PMID:22546480 More... NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472 		JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 multiple interactions
increases expression
increases activity		 ISO
EXP		 [vinclozolin co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP19A1 mRNA; Atrazine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of CYP19A1 protein]; Atrazine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP19A1 mRNA]; bisphenol A inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of CYP19A1 protein]; formestane inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of CYP19A1 protein]; Methoxychlor inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of CYP19A1 protein]
[NR5A1 protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP19A1 mRNA
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP19A1 mRNA; 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP19A1 protein		 CTD PMID:10746939 PMID:18815356 PMID:21126571 PMID:21610156 PMID:22120136 More... NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 increases expression EXP
ISO		 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP1B1 mRNA
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP1B1 mRNA; 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP1B1 protein		 CTD PMID:7588239 PMID:22079614 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G CYP21A2 cytochrome P450 family 21 subfamily A member 2 increases expression
multiple interactions		 EXP
ISO		 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP21A2 mRNA
[NR5A1 protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP21A1 mRNA
bifenthrin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP21A2 mRNA]; Mitotane inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP21A2 mRNA]		 CTD PMID:21610156 PMID:22079614 PMID:22546480 PMID:34896276 NCBI chr 6:32,038,415...32,041,644
Ensembl chr 6:32,038,327...32,041,644 		JBrowse link
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CYP27A1 mRNA CTD PMID:22079614 NCBI chr 2:218,782,147...218,815,293
Ensembl chr 2:218,781,749...218,815,293 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP2E1 mRNA CTD PMID:22079614 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G CYP2F1 cytochrome P450 family 2 subfamily F member 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CYP2F1 mRNA CTD PMID:22079614 NCBI chr19:41,114,432...41,128,381
Ensembl chr19:41,114,432...41,128,381 		JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CYP3A5 mRNA CTD PMID:22079614 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996 		JBrowse link
G CYP3A7 cytochrome P450 family 3 subfamily A member 7 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CYP3A7 mRNA CTD PMID:22079614 NCBI chr 7:99,705,036...99,735,196
Ensembl chr 7:99,705,036...99,735,196 		JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 increases expression
multiple interactions		 EXP
ISO		 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP51A1 mRNA
[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP51 mRNA; [monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP51 protein; naphthol AS-E phosphate inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP51 mRNA]; naphthol AS-E phosphate inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP51 protein]		 CTD PMID:18467523 PMID:22079614 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803 		JBrowse link
G CYP8B1 cytochrome P450 family 8 subfamily B member 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP8B1 mRNA CTD PMID:22079614 NCBI chr 3:42,872,192...42,875,879
Ensembl chr 3:42,856,005...42,875,898 		JBrowse link
G CYTH1 cytohesin 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYTH1 mRNA CTD PMID:22079614 NCBI chr17:78,674,048...78,782,273
Ensembl chr17:78,674,048...78,782,297 		JBrowse link
G DACH2 dachshund family transcription factor 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of DACH2 mRNA CTD PMID:22079614 NCBI chr  X:86,148,451...86,832,602
Ensembl chr  X:86,148,451...86,832,604 		JBrowse link
G DACT1 dishevelled binding antagonist of beta catenin 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of DACT1 mRNA CTD PMID:22079614 NCBI chr14:58,634,061...58,648,321
Ensembl chr14:58,633,967...58,648,321 		JBrowse link
G DAZ2 deleted in azoospermia 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DAZ2 mRNA CTD PMID:22079614 NCBI chr  Y:23,219,457...23,291,356
Ensembl chr  Y:23,219,447...23,291,356 		JBrowse link
G DBIL5P diazepam binding inhibitor-like 5, pseudogene increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DBIL5P mRNA CTD PMID:22079614 NCBI chr17:752,333...755,336
Ensembl chr17:752,884...753,133 		JBrowse link
G DCAF12L1 DDB1 and CUL4 associated factor 12 like 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DCAF12L1 mRNA CTD PMID:22079614 NCBI chr  X:126,549,383...126,552,814
Ensembl chr  X:126,549,383...126,552,814 		JBrowse link
G DCBLD2 discoidin, CUB and LCCL domain containing 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DCBLD2 mRNA CTD PMID:22079614 NCBI chr 3:98,795,941...98,901,695
Ensembl chr 3:98,795,941...98,901,695 		JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of DGAT2 mRNA CTD PMID:22079614 NCBI chr11:75,768,778...75,801,534
Ensembl chr11:75,759,512...75,801,535 		JBrowse link
G DGKB diacylglycerol kinase beta increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DGKB mRNA CTD PMID:22079614 NCBI chr 7:14,145,049...14,974,858
Ensembl chr 7:14,145,049...14,974,777 		JBrowse link
G DHCR24 24-dehydrocholesterol reductase increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DHCR24 mRNA CTD PMID:22079614 NCBI chr 1:54,849,627...54,887,195
Ensembl chr 1:54,849,627...54,887,195 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DHCR7 mRNA CTD PMID:22079614 NCBI chr11:71,434,411...71,448,393
Ensembl chr11:71,428,193...71,452,868 		JBrowse link
G DHRS2 dehydrogenase/reductase 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of DHRS2 mRNA CTD PMID:22079614 NCBI chr14:23,630,115...23,645,639
Ensembl chr14:23,630,115...23,645,639 		JBrowse link
G DHRS3 dehydrogenase/reductase 3 multiple interactions EXP 7-propyl spirolactone inhibits the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of DHRS3 protein]; [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of DHRS3 mRNA; [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of DHRS3 protein; Aldosterone promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of DHRS3 protein]; NR3C2 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of DHRS3 mRNA] CTD PMID:23275455 NCBI chr 1:12,567,910...12,618,210
Ensembl chr 1:12,567,910...12,618,210 		JBrowse link
G DIO2 iodothyronine deiodinase 2 multiple interactions
increases activity		 EXP
ISO		 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of and results in increased activity of DIO2 protein
8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO2 protein
Acetylcysteine inhibits the reaction [Hydrogen Peroxide inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO2 protein]]; Hydrogen Peroxide inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO2 protein]; Sodium Selenite inhibits the reaction [Hydrogen Peroxide inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO2 protein]]		 CTD PMID:11425850 PMID:18420745 NCBI chr14:80,197,526...80,231,057
Ensembl chr14:80,197,526...80,387,757 		JBrowse link
G DIO3 iodothyronine deiodinase 3 multiple interactions ISO Acetylcysteine inhibits the reaction [[Hydrogen Peroxide co-treated with Sodium Selenite] promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO3 protein]]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO3 protein]]; Hydrogen Peroxide promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO3 protein] CTD PMID:18420745 NCBI chr14:101,561,495...101,563,452
Ensembl chr14:101,560,139...101,563,452 		JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DKK1 mRNA CTD PMID:22079614 NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042 		JBrowse link
G DLEU2 deleted in lymphocytic leukemia 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of DLEU2 mRNA CTD PMID:22079614 NCBI chr13:49,982,549...50,125,541
Ensembl chr13:49,956,670...50,125,720 		JBrowse link
G DNAH5 dynein axonemal heavy chain 5 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DNAH5 mRNA CTD PMID:22079614 NCBI chr 5:13,690,328...14,011,818
Ensembl chr 5:13,690,328...14,011,818 		JBrowse link
G DNAJB3 DnaJ heat shock protein family (Hsp40) member B3 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of DNAJB3 mRNA CTD PMID:22079614 NCBI chr 2:233,742,750...233,743,998
Ensembl chr 2:233,743,188...233,743,916
Ensembl chr 2:233,743,188...233,743,916 		JBrowse link
G DNAJB7 DnaJ heat shock protein family (Hsp40) member B7 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DNAJB7 mRNA CTD PMID:22079614 NCBI chr22:40,859,549...40,862,113
Ensembl chr22:40,859,549...40,862,113 		JBrowse link
G DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DNAJB9 mRNA CTD PMID:22079614 NCBI chr 7:108,569,874...108,574,850
Ensembl chr 7:108,569,867...108,574,850 		JBrowse link
G DNER delta/notch like EGF repeat containing increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DNER mRNA CTD PMID:22079614 NCBI chr 2:229,357,629...229,714,555
Ensembl chr 2:229,357,629...229,714,555 		JBrowse link
G DOCK11 dedicator of cytokinesis 11 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DOCK11 mRNA CTD PMID:22079614 NCBI chr  X:118,495,815...118,686,147
Ensembl chr  X:118,495,815...118,686,163 		JBrowse link
G DOK5 docking protein 5 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DOK5 mRNA CTD PMID:22079614 NCBI chr20:54,475,593...54,651,169
Ensembl chr20:54,475,593...54,651,169 		JBrowse link
G DUSP1 dual specificity phosphatase 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DUSP1 mRNA CTD PMID:22079614 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195 		JBrowse link
G DUSP16 dual specificity phosphatase 16 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DUSP16 mRNA CTD PMID:22079614 NCBI chr12:12,473,282...12,562,863
Ensembl chr12:12,473,282...12,562,863 		JBrowse link
G DUSP4 dual specificity phosphatase 4 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DUSP4 mRNA CTD PMID:20147733 NCBI chr 8:29,333,064...29,350,684
Ensembl chr 8:29,333,064...29,350,684 		JBrowse link
G DUSP6 dual specificity phosphatase 6 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of DUSP6 mRNA CTD PMID:22079614 NCBI chr12:89,347,235...89,352,501
Ensembl chr12:89,347,235...89,352,501 		JBrowse link
G EBP EBP cholestenol delta-isomerase increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of EBP mRNA CTD PMID:22079614 NCBI chr  X:48,521,808...48,528,716
Ensembl chr  X:48,521,799...48,528,716 		JBrowse link
G ECHS1 enoyl-CoA hydratase, short chain 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ECHS1 mRNA CTD PMID:22079614 NCBI chr10:133,362,485...133,373,354
Ensembl chr10:133,362,485...133,373,354 		JBrowse link
G EGF epidermal growth factor multiple interactions ISO EGF protein inhibits the reaction [naphthol AS-E phosphate inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; EGF protein inhibits the reaction [naphthol AS-E phosphate inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of and results in increased activity of MAPK3 protein]] CTD PMID:18467523 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G EGFR epidermal growth factor receptor increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of EGFR mRNA CTD PMID:22079614 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EGR1 early growth response 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of EGR1 mRNA CTD PMID:22079614 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303 		JBrowse link
G EGR2 early growth response 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of EGR2 mRNA CTD PMID:20147733 PMID:22079614 NCBI chr10:62,811,996...62,819,167
Ensembl chr10:62,811,996...62,819,167 		JBrowse link
G ELP1 elongator acetyltransferase complex subunit 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ELP1 mRNA CTD PMID:22079614 NCBI chr 9:108,867,517...108,934,124
Ensembl chr 9:108,866,898...108,934,328 		JBrowse link
G EMP2 epithelial membrane protein 2 multiple interactions
decreases expression		 EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of EMP2 mRNA
8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of EMP2 mRNA		 CTD PMID:16997883 PMID:22079614 NCBI chr16:10,528,422...10,580,598
Ensembl chr16:10,528,422...10,580,632 		JBrowse link
G ENOX1 ecto-NOX disulfide-thiol exchanger 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ENOX1 mRNA CTD PMID:20147733 NCBI chr13:43,213,130...43,786,972
Ensembl chr13:43,213,130...43,786,972 		JBrowse link
G EP300 E1A binding protein p300 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of EP300 mRNA CTD PMID:22079614 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,592...41,180,077 		JBrowse link
G EPG5 ectopic P-granules 5 autophagy tethering factor decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of EPG5 mRNA CTD PMID:20147733 NCBI chr18:45,800,581...45,967,329
Ensembl chr18:45,800,581...45,967,329 		JBrowse link
G EPHX1 epoxide hydrolase 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of EPHX1 mRNA CTD PMID:22079614 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563 		JBrowse link
G ERAP1 endoplasmic reticulum aminopeptidase 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ERAP1 mRNA CTD PMID:22079614 NCBI chr 5:96,760,813...96,935,854
Ensembl chr 5:96,760,810...96,808,100 		JBrowse link
G ERF ETS2 repressor factor decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ERF mRNA CTD PMID:22079614 NCBI chr19:42,247,569...42,255,128
Ensembl chr19:42,247,569...42,255,128 		JBrowse link
G ESR2 estrogen receptor 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ESR2 mRNA CTD PMID:22079614 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G ESRRA estrogen related receptor alpha increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ESRRA mRNA CTD PMID:23166782 NCBI chr11:64,305,524...64,316,743
Ensembl chr11:64,305,497...64,316,743 		JBrowse link
G ESRRG estrogen related receptor gamma decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ESRRG mRNA CTD PMID:22079614 NCBI chr 1:216,503,246...217,137,702
Ensembl chr 1:216,503,246...217,137,755 		JBrowse link
G ETNPPL ethanolamine-phosphate phospho-lyase increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ETNPPL mRNA CTD PMID:22079614 NCBI chr 4:108,742,053...108,763,053
Ensembl chr 4:108,742,048...108,763,054 		JBrowse link
G ETV1 ETS variant transcription factor 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ETV1 mRNA CTD PMID:20147733 NCBI chr 7:13,891,229...13,991,425
Ensembl chr 7:13,891,229...13,991,425 		JBrowse link
G ETV5 ETS variant transcription factor 5 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ETV5 mRNA CTD PMID:22079614 NCBI chr 3:186,046,314...186,109,089
Ensembl chr 3:186,046,314...186,110,318 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit decreases expression
multiple interactions		 EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of EZH2 mRNA; 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of EZH2 protein
[8-Bromo Cyclic Adenosine Monophosphate co-treated with Medroxyprogesterone Acetate] results in decreased expression of EZH2 mRNA; [8-Bromo Cyclic Adenosine Monophosphate co-treated with Medroxyprogesterone Acetate] results in decreased expression of EZH2 protein; EZH2 mutant form inhibits the reaction [[8-Bromo Cyclic Adenosine Monophosphate co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 mRNA]; EZH2 mutant form inhibits the reaction [[8-Bromo Cyclic Adenosine Monophosphate co-treated with Medroxyprogesterone Acetate] results in increased expression of PRL mRNA]		 CTD PMID:21903722 NCBI chr 7:148,807,383...148,884,291
Ensembl chr 7:148,807,257...148,884,321 		JBrowse link
G F2RL2 coagulation factor II thrombin receptor like 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of F2RL2 mRNA CTD PMID:20147733 NCBI chr 5:76,615,482...76,623,403
Ensembl chr 5:76,615,482...76,623,413 		JBrowse link
G FABP1 fatty acid binding protein 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FABP1 mRNA CTD PMID:22079614 NCBI chr 2:88,122,982...88,128,062
Ensembl chr 2:88,122,982...88,128,062 		JBrowse link
G FADS1 fatty acid desaturase 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FADS1 mRNA CTD PMID:22079614 NCBI chr11:61,799,627...61,817,003
Ensembl chr11:61,799,627...61,829,318 		JBrowse link
G FASLG Fas ligand multiple interactions EXP [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of FASLG protein CTD PMID:16709600 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FBLN1 fibulin 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FBLN1 mRNA CTD PMID:15774544 NCBI chr22:45,502,883...45,601,135
Ensembl chr22:45,502,238...45,601,135 		JBrowse link
G FBXO32 F-box protein 32 multiple interactions EXP [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of FBXO32 mRNA; NR3C2 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of FBXO32 mRNA] CTD PMID:23275455 NCBI chr 8:123,497,889...123,541,206
Ensembl chr 8:123,497,889...123,541,206 		JBrowse link
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FDFT1 mRNA CTD PMID:22079614 NCBI chr 8:11,795,582...11,839,309
Ensembl chr 8:11,795,573...11,839,395 		JBrowse link
G FDX1 ferredoxin 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FDX1 mRNA CTD PMID:22079614 NCBI chr11:110,429,331...110,464,884
Ensembl chr11:110,429,948...110,464,884 		JBrowse link
G FDXR ferredoxin reductase increases expression
multiple interactions		 ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FDXR protein
Hydrocarbons, Chlorinated inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FDXR protein]		 CTD PMID:24740604 NCBI chr17:74,862,497...74,872,994
Ensembl chr17:74,862,497...74,873,031 		JBrowse link
G FER1L6 fer-1 like family member 6 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FER1L6 mRNA CTD PMID:20147733 NCBI chr 8:123,851,987...124,120,061
Ensembl chr 8:123,851,987...124,120,061 		JBrowse link
G FGF10 fibroblast growth factor 10 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FGF10 mRNA CTD PMID:20147733 NCBI chr 5:44,300,247...44,389,420
Ensembl chr 5:44,300,247...44,389,706 		JBrowse link
G FGF13 fibroblast growth factor 13 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of FGF13 mRNA CTD PMID:22079614 NCBI chr  X:138,614,727...139,205,023
Ensembl chr  X:138,614,727...139,222,777 		JBrowse link
G FGF9 fibroblast growth factor 9 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FGF9 mRNA CTD PMID:22079614 NCBI chr13:21,671,073...21,704,498
Ensembl chr13:21,671,073...21,704,498 		JBrowse link
G FHL2 four and a half LIM domains 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FHL2 mRNA CTD PMID:22079614 NCBI chr 2:105,357,712...105,438,529
Ensembl chr 2:105,357,712...105,438,513 		JBrowse link
G FLOT1 flotillin 1 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of FLOT1 mRNA CTD PMID:16997883 NCBI chr 6:30,727,709...30,742,687
Ensembl chr 6:30,727,709...30,742,732 		JBrowse link
G FLOT2 flotillin 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of FLOT2 mRNA CTD PMID:22079614 NCBI chr17:28,879,339...28,897,733
Ensembl chr17:28,879,335...28,897,733 		JBrowse link
G FN1 fibronectin 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of FN1 mRNA CTD PMID:22079614 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073 		JBrowse link
G FOXO1 forkhead box O1 multiple interactions EXP [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of FOXO1 mRNA; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of FOXO1 protein; FOXO1 protein affects the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in decreased expression of FOXO3 mRNA]; FOXO1 protein affects the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of SOD2 mRNA]; FOXO1 protein affects the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased secretion of IGFBP1 protein]; FOXO1 protein affects the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased secretion of PRL protein]; Hydrogen Peroxide inhibits the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of FOXO1 mRNA]; Hydrogen Peroxide inhibits the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of FOXO1 protein] CTD PMID:16709600 NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641 		JBrowse link
G FOXO3 forkhead box O3 multiple interactions EXP [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] inhibits the reaction [Hydrogen Peroxide results in increased expression of FOXO3 mRNA]; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] inhibits the reaction [Hydrogen Peroxide results in increased expression of FOXO3 protein]; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in decreased expression of FOXO3 mRNA; FOXO1 protein affects the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in decreased expression of FOXO3 mRNA] CTD PMID:16709600 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774 		JBrowse link
G FOXR1 forkhead box R1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FOXR1 mRNA CTD PMID:22079614 NCBI chr11:118,971,761...118,981,287
Ensembl chr11:118,971,712...118,981,287 		JBrowse link
G FRAS1 Fraser extracellular matrix complex subunit 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FRAS1 mRNA CTD PMID:22079614 NCBI chr 4:78,057,323...78,544,269
Ensembl chr 4:78,057,323...78,544,269 		JBrowse link
G FSHB follicle stimulating hormone subunit beta increases expression
multiple interactions		 ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FSHB mRNA; 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FSHB protein
Tetrachlorodibenzodioxin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FSHB mRNA]		 CTD PMID:8404651 PMID:10746652 PMID:21467749 NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261 		JBrowse link
G FZD10 frizzled class receptor 10 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FZD10 mRNA CTD PMID:22079614 NCBI chr12:130,162,464...130,165,740
Ensembl chr12:130,162,459...130,165,740 		JBrowse link
G FZD4 frizzled class receptor 4 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FZD4 mRNA CTD PMID:20147733 PMID:22079614 NCBI chr11:86,945,679...86,955,395
Ensembl chr11:86,945,679...86,955,395 		JBrowse link
G FZD7 frizzled class receptor 7 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of FZD7 mRNA CTD PMID:22079614 NCBI chr 2:202,033,855...202,038,441
Ensembl chr 2:202,033,855...202,038,441 		JBrowse link
G GABBR2 gamma-aminobutyric acid type B receptor subunit 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of GABBR2 mRNA CTD PMID:22079614 NCBI chr 9:98,288,109...98,708,935
Ensembl chr 9:98,288,109...98,708,935 		JBrowse link
G GABRA4 gamma-aminobutyric acid type A receptor subunit alpha4 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GABRA4 mRNA CTD PMID:22079614 NCBI chr 4:46,918,900...46,993,581
Ensembl chr 4:46,918,900...46,993,581 		JBrowse link
G GABRG1 gamma-aminobutyric acid type A receptor subunit gamma1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GABRG1 mRNA CTD PMID:22079614 NCBI chr 4:46,035,769...46,124,054
Ensembl chr 4:46,035,769...46,124,054 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha multiple interactions EXP [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of GADD45A mRNA; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of GADD45A protein CTD PMID:16709600 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334 		JBrowse link
G GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GALNT12 mRNA CTD PMID:20147733 NCBI chr 9:98,807,670...98,850,081
Ensembl chr 9:98,807,670...98,850,081 		JBrowse link
G GALR1 galanin receptor 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GALR1 mRNA CTD PMID:22079614 NCBI chr18:77,249,848...77,277,900
Ensembl chr18:77,249,848...77,277,900 		JBrowse link
G GAP43 growth associated protein 43 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GAP43 mRNA CTD PMID:20147733 NCBI chr 3:115,623,510...115,721,483
Ensembl chr 3:115,623,510...115,721,490 		JBrowse link
G GCK glucokinase decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of GCK mRNA CTD PMID:22079614 NCBI chr 7:44,143,213...44,189,439
Ensembl chr 7:44,143,213...44,198,170 		JBrowse link
G GCNA germ cell nuclear acidic peptidase increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GCNA mRNA CTD PMID:22079614 NCBI chr  X:71,578,437...71,613,583
Ensembl chr  X:71,578,437...71,613,583 		JBrowse link
G GCSAM germinal center associated signaling and motility increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GCSAM mRNA CTD PMID:22079614 NCBI chr 3:112,120,839...112,133,248
Ensembl chr 3:112,120,839...112,133,270 		JBrowse link
G GDF10 growth differentiation factor 10 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GDF10 mRNA CTD PMID:22079614 NCBI chr10:47,300,197...47,313,577
Ensembl chr10:47,300,197...47,313,577 		JBrowse link
G GDF15 growth differentiation factor 15 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GDF15 mRNA CTD PMID:22079614 NCBI chr19:18,386,158...18,389,176
Ensembl chr19:18,374,731...18,389,176 		JBrowse link
G GFAP glial fibrillary acidic protein increases expression
multiple interactions		 ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GFAP mRNA
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [ochratoxin A results in decreased expression of GFAP mRNA]		 CTD PMID:15994020 NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937 		JBrowse link
G GFPT2 glutamine-fructose-6-phosphate transaminase 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GFPT2 mRNA CTD PMID:20147733 NCBI chr 5:180,300,698...180,353,336
Ensembl chr 5:180,300,698...180,353,336 		JBrowse link
G GJA1 gap junction protein alpha 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GJA1 mRNA CTD PMID:22079614 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727 		JBrowse link
G GJB2 gap junction protein beta 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GJB2 mRNA CTD PMID:22079614 NCBI chr13:20,187,470...20,192,938
Ensembl chr13:20,187,463...20,192,938 		JBrowse link
G GK glycerol kinase increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GK mRNA CTD PMID:22079614 NCBI chr  X:30,653,423...30,731,462
Ensembl chr  X:30,653,359...30,731,462 		JBrowse link
G GLIPR1 GLI pathogenesis related 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GLIPR1 mRNA CTD PMID:20147733 NCBI chr12:75,480,755...75,503,863
Ensembl chr12:75,480,753...75,503,863 		JBrowse link
G GLRX glutaredoxin increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GLRX mRNA CTD PMID:22079614 NCBI chr 5:95,813,849...95,822,726
Ensembl chr 5:95,751,319...95,822,726 		JBrowse link
G GNAI2 G protein subunit alpha i2 multiple interactions ISO 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of GNAI2 protein] CTD PMID:19252090 NCBI chr 3:50,227,068...50,263,358
Ensembl chr 3:50,226,292...50,259,362 		JBrowse link
G GNAI3 G protein subunit alpha i3 multiple interactions ISO 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of GNAI3 protein] CTD PMID:19252090 NCBI chr 1:109,548,615...109,600,195
Ensembl chr 1:109,548,615...109,600,195 		JBrowse link
G GNG2 G protein subunit gamma 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of GNG2 mRNA CTD PMID:22079614 NCBI chr14:51,826,174...51,969,795
Ensembl chr14:51,826,195...51,979,342 		JBrowse link
G GPR22 G protein-coupled receptor 22 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of GPR22 mRNA CTD PMID:22079614 NCBI chr 7:107,470,057...107,477,845
Ensembl chr 7:107,470,018...107,475,684 		JBrowse link
G GPR37 G protein-coupled receptor 37 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of GPR37 mRNA CTD PMID:22079614 NCBI chr 7:124,743,885...124,765,792
Ensembl chr 7:124,743,885...124,765,792 		JBrowse link
G GPX1 glutathione peroxidase 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GPX1 mRNA CTD PMID:22079614 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GRB10 growth factor receptor bound protein 10 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GRB10 mRNA CTD PMID:22079614 NCBI chr 7:50,590,068...50,793,453
Ensembl chr 7:50,590,063...50,793,462 		JBrowse link
G GRB14 growth factor receptor bound protein 14 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of GRB14 mRNA CTD PMID:22079614 NCBI chr 2:164,492,417...164,621,482
Ensembl chr 2:164,492,417...164,621,482 		JBrowse link
G GREM2 gremlin 2, DAN family BMP antagonist increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GREM2 mRNA CTD PMID:20147733 PMID:22079614 NCBI chr 1:240,489,573...240,612,155
Ensembl chr 1:240,489,573...240,612,155 		JBrowse link
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 multiple interactions EXP [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in decreased expression of GRIA1 mRNA; NR3C1 protein inhibits the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in decreased expression of GRIA1 mRNA]; NR3C2 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in decreased expression of GRIA1 mRNA] CTD PMID:23275455 NCBI chr 5:153,489,615...153,813,869
Ensembl chr 5:153,489,615...153,813,869 		JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of GRIN3A mRNA CTD PMID:22079614 NCBI chr 9:101,569,352...101,738,647
Ensembl chr 9:101,569,352...101,738,647 		JBrowse link
G GSTA2 glutathione S-transferase alpha 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of GSTA2 mRNA CTD PMID:22079614 NCBI chr 6:52,750,087...52,763,475
Ensembl chr 6:52,750,087...52,763,475 		JBrowse link
G GSTM2 glutathione S-transferase mu 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of GSTM2 mRNA CTD PMID:22079614 NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551 		JBrowse link
G GSTM4 glutathione S-transferase mu 4 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GSTM4 mRNA CTD PMID:20147733 NCBI chr 1:109,656,099...109,667,727
Ensembl chr 1:109,656,099...109,665,496 		JBrowse link
G HAS2 hyaluronan synthase 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HAS2 mRNA CTD PMID:20147733 NCBI chr 8:121,612,116...121,641,440
Ensembl chr 8:121,612,116...121,641,440 		JBrowse link
G HBG1 hemoglobin subunit gamma 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HBG1 mRNA CTD PMID:22079614 NCBI chr11:5,248,269...5,249,857
Ensembl chr11:5,248,269...5,249,857 		JBrowse link
G HDAC3 histone deacetylase 3 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of HDAC3 mRNA CTD PMID:22079614 NCBI chr 5:141,620,881...141,636,849
Ensembl chr 5:141,620,876...141,636,849 		JBrowse link
G HDAC5 histone deacetylase 5 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of HDAC5 mRNA CTD PMID:22079614 NCBI chr17:44,076,753...44,123,641
Ensembl chr17:44,076,746...44,123,702 		JBrowse link
G HEY2 hes related family bHLH transcription factor with YRPW motif 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of HEY2 mRNA CTD PMID:22079614 NCBI chr 6:125,749,632...125,761,269
Ensembl chr 6:125,747,664...125,761,269 		JBrowse link
G HLF HLF transcription factor, PAR bZIP family member decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of HLF mRNA CTD PMID:22079614 NCBI chr17:55,264,960...55,325,187
Ensembl chr17:55,264,960...55,325,187 		JBrowse link
G HMGA1 high mobility group AT-hook 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HMGA1 mRNA CTD PMID:22079614 NCBI chr 6:34,236,873...34,246,231
Ensembl chr 6:34,236,873...34,246,231 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HMGCS1 mRNA CTD PMID:22079614 NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512 		JBrowse link
G HMOX1 heme oxygenase 1 increases expression
multiple interactions		 ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HMOX1 mRNA
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [ochratoxin A results in increased expression of HMOX1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HMOX1 mRNA]		 CTD PMID:15179140 PMID:15994020 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HNF4G hepatocyte nuclear factor 4 gamma increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HNF4G mRNA CTD PMID:22079614 NCBI chr 8:75,407,649...75,566,834
Ensembl chr 8:75,407,914...75,566,834 		JBrowse link
G HOXB9 homeobox B9 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HOXB9 mRNA CTD PMID:22079614 NCBI chr17:48,621,156...48,626,358
Ensembl chr17:48,621,156...48,626,358 		JBrowse link
G HPCA hippocalcin decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of HPCA mRNA CTD PMID:22079614 NCBI chr 1:32,885,996...32,894,646
Ensembl chr 1:32,885,994...32,898,441 		JBrowse link
G HS3ST1 heparan sulfate-glucosamine 3-sulfotransferase 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of HS3ST1 mRNA CTD PMID:22079614 NCBI chr 4:11,393,150...11,434,327
Ensembl chr 4:11,393,150...11,429,564 		JBrowse link
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 multiple interactions EXP 4'-cyanobiphenyl-4-sulfonic acid (6-aminopyridin-2-yl)amide inhibits the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of HSD11B1 mRNA]; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of and results in increased activity of HSD11B1 protein; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of HSD11B1 mRNA; [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of HSD11B1 protein; [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of HSD11B1 mRNA; Hydrocortisone promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of HSD11B1 mRNA] CTD PMID:23275455 NCBI chr 1:209,686,179...209,734,929
Ensembl chr 1:209,686,178...209,734,949 		JBrowse link
G HSD11B2 hydroxysteroid 11-beta dehydrogenase 2 decreases expression
multiple interactions		 EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of HSD11B2 mRNA
[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of HSD11B2 protein		 CTD PMID:22079614 PMID:23275455 NCBI chr16:67,429,801...67,437,553
Ensembl chr16:67,430,652...67,437,553 		JBrowse link
G HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 multiple interactions
increases expression		 EXP 8-Bromo Cyclic Adenosine Monophosphate promotes the reaction [bisphenol A results in decreased expression of HSD17B1 mRNA]
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HSD17B1 mRNA		 CTD PMID:18815356 PMID:21273127 NCBI chr17:42,552,923...42,555,214
Ensembl chr17:42,552,922...42,555,214 		JBrowse link
G HSD17B14 hydroxysteroid 17-beta dehydrogenase 14 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of HSD17B14 mRNA CTD PMID:22079614 NCBI chr19:48,813,018...48,836,491
Ensembl chr19:48,813,018...48,836,510 		JBrowse link
G HSD17B2 hydroxysteroid 17-beta dehydrogenase 2 multiple interactions
increases expression		 EXP
ISO		 bisphenol A inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HSD17B2 mRNA]
[NR5A1 protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate] affects the expression of HSD17B2 mRNA
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HSD17B2 mRNA; 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HSD17B2 protein		 CTD PMID:18815356 PMID:21273127 PMID:21610156 NCBI chr16:82,035,253...82,098,534
Ensembl chr16:82,035,004...82,098,534 		JBrowse link
G HSD17B3 hydroxysteroid 17-beta dehydrogenase 3 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HSD17B3 mRNA CTD PMID:22079614 NCBI chr 9:96,235,306...96,302,176
Ensembl chr 9:96,235,306...96,302,176 		JBrowse link
G HSD17B4 hydroxysteroid 17-beta dehydrogenase 4 multiple interactions EXP [4-nitro-3-cresol co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of HSD17B4 protein CTD PMID:18336853 NCBI chr 5:119,452,497...119,542,332
Ensembl chr 5:119,452,465...119,637,199 		JBrowse link
G HSD17B7 hydroxysteroid 17-beta dehydrogenase 7 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HSD17B7 mRNA CTD PMID:22079614 NCBI chr 1:162,790,702...162,812,823
Ensembl chr 1:162,790,702...162,812,823 		JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression
increases expression
multiple interactions		 EXP
ISO		 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of HSD3B1 mRNA
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HSD3B1 mRNA; 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HSD3B1 protein
2,2',4,4'-tetrahydroxybenzophenone promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HSD3B1 mRNA]; THRA mutant form inhibits the reaction [2,2',4,4'-tetrahydroxybenzophenone promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HSD3B1 mRNA]]; Triiodothyronine inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HSD3B1 mRNA]		 CTD PMID:18815356 PMID:21726595 PMID:22079614 NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054 		JBrowse link
G HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 multiple interactions
increases expression		 EXP [4-nitro-3-cresol co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in decreased expression of HSD3B2 protein; bifenthrin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HSD3B2 mRNA]; Mitotane inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HSD3B2 mRNA] CTD PMID:18336853 PMID:22079614 PMID:22546480 PMID:34896276 NCBI chr 1:119,414,931...119,423,034
Ensembl chr 1:119,414,931...119,423,035 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of HSP90AA1 mRNA CTD PMID:22079614 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of HSPA1A mRNA CTD PMID:22079614 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HSPA5 mRNA CTD PMID:22079614 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of HSPA8 mRNA CTD PMID:22079614 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230 		JBrowse link
G HSPH1 heat shock protein family H (Hsp110) member 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HSPH1 mRNA CTD PMID:22079614 NCBI chr13:31,134,973...31,162,388
Ensembl chr13:31,134,973...31,162,388 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions ISO 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Reactive Oxygen Species results in increased expression of ICAM1 mRNA]; 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA] CTD PMID:10495789 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G ICAM2 intercellular adhesion molecule 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ICAM2 mRNA CTD PMID:22079614 NCBI chr17:64,002,595...64,020,633
Ensembl chr17:64,002,594...64,020,634 		JBrowse link
G ID1 inhibitor of DNA binding 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ID1 mRNA CTD PMID:22079614 NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,605,283...31,606,515 		JBrowse link
G IDI1 isopentenyl-diphosphate delta isomerase 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IDI1 mRNA CTD PMID:22079614 NCBI chr10:1,039,152...1,056,704
Ensembl chr10:1,039,152...1,049,119 		JBrowse link
G IER3 immediate early response 3 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IER3 mRNA CTD PMID:20147733 NCBI chr 6:30,743,199...30,744,547
Ensembl chr 6:30,743,199...30,744,548 		JBrowse link
G IGF1 insulin like growth factor 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IGF1 mRNA CTD PMID:20147733 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G IGF2BP2 insulin like growth factor 2 mRNA binding protein 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IGF2BP2 mRNA CTD PMID:22079614 NCBI chr 3:185,643,130...185,825,042
Ensembl chr 3:185,643,130...185,825,042 		JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 multiple interactions
increases expression
decreases expression
increases secretion		 EXP 1-Butanol inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IGFBP1 mRNA]; 4'-cyanobiphenyl-4-sulfonic acid (6-aminopyridin-2-yl)amide inhibits the reaction [Progesterone promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IGFBP1 mRNA]]; [8-Bromo Cyclic Adenosine Monophosphate co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 mRNA; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased secretion of IGFBP1 protein; Dexamethasone promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IGFBP1 mRNA]; EZH2 mutant form inhibits the reaction [[8-Bromo Cyclic Adenosine Monophosphate co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 mRNA]; FOXO1 protein affects the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased secretion of IGFBP1 protein]; Hydrocortisone promotes the reaction [Progesterone promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IGFBP1 mRNA]]; PLD1 protein affects the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IGFBP1 mRNA]; Progesterone promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IGFBP1 mRNA]
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IGFBP1 mRNA; 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IGFBP1 protein
8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of IGFBP1 mRNA; 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of IGFBP1 protein
8-Bromo Cyclic Adenosine Monophosphate results in increased secretion of IGFBP1 protein		 CTD PMID:16709600 PMID:17065600 PMID:18815356 PMID:20147733 PMID:21273127 More... NCBI chr 7:45,888,488...45,893,660
Ensembl chr 7:45,888,360...45,893,660 		JBrowse link
G IGFBP5 insulin like growth factor binding protein 5 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IGFBP5 mRNA CTD PMID:20147733 PMID:22079614 NCBI chr 2:216,672,105...216,695,549
Ensembl chr 2:216,672,105...216,695,549 		JBrowse link
G IKZF1 IKAROS family zinc finger 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of IKZF1 mRNA CTD PMID:22079614 NCBI chr 7:50,303,455...50,405,101
Ensembl chr 7:50,304,068...50,405,101 		JBrowse link
G IL18 interleukin 18 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IL18 mRNA CTD PMID:22079614 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL1A interleukin 1 alpha multiple interactions
increases expression		 EXP 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]]
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IL1A mRNA		 CTD PMID:11230753 PMID:22079614 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta multiple interactions EXP 8-Bromo Cyclic Adenosine Monophosphate promotes the reaction [IL1B protein results in increased expression of PTGS2 protein] CTD PMID:11112151 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL27RA interleukin 27 receptor subunit alpha increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IL27RA mRNA CTD PMID:22079614 NCBI chr19:14,031,762...14,053,218
Ensembl chr19:14,031,762...14,053,218 		JBrowse link
G IL32 interleukin 32 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of IL32 mRNA CTD PMID:16997883 NCBI chr16:3,065,403...3,069,530
Ensembl chr16:3,065,297...3,082,192 		JBrowse link
G IL4 interleukin 4 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IL4 mRNA CTD PMID:22079614 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL4R interleukin 4 receptor increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IL4R mRNA CTD PMID:20147733 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778 		JBrowse link
G IL6 interleukin 6 multiple interactions EXP
ISO		 [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of IL6 mRNA
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]		 CTD PMID:16997883 PMID:21803157 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IL7R interleukin 7 receptor increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IL7R mRNA CTD PMID:22079614 NCBI chr 5:35,856,891...35,879,603
Ensembl chr 5:35,852,695...35,879,603 		JBrowse link
G INHBA inhibin subunit beta A increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of INHBA mRNA CTD PMID:20147733 PMID:22079614 NCBI chr 7:41,685,114...41,705,406
Ensembl chr 7:41,667,168...41,705,834 		JBrowse link
G INSIG1 insulin induced gene 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of INSIG1 mRNA CTD PMID:22079614 NCBI chr 7:155,297,878...155,310,235
Ensembl chr 7:155,297,776...155,310,235 		JBrowse link
G INSM2 INSM transcriptional repressor 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of INSM2 mRNA CTD PMID:22079614 NCBI chr14:35,534,164...35,537,054
Ensembl chr14:35,534,164...35,537,054 		JBrowse link
G IQGAP2 IQ motif containing GTPase activating protein 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of IQGAP2 mRNA CTD PMID:22079614 NCBI chr 5:76,403,285...76,708,132
Ensembl chr 5:76,403,285...76,708,132 		JBrowse link
G IRS1 insulin receptor substrate 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IRS1 mRNA CTD PMID:22079614 NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,312...226,799,820 		JBrowse link
G ISM1 isthmin 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ISM1 mRNA CTD PMID:20147733 NCBI chr20:13,221,274...13,326,723
Ensembl chr20:13,221,274...13,300,651 		JBrowse link
G ITGA2 integrin subunit alpha 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ITGA2 mRNA CTD PMID:20147733 NCBI chr 5:52,989,352...53,094,779
Ensembl chr 5:52,989,340...53,094,779 		JBrowse link
G ITPKB inositol-trisphosphate 3-kinase B increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ITPKB mRNA CTD PMID:22079614 NCBI chr 1:226,631,690...226,739,282
Ensembl chr 1:226,631,690...226,739,323 		JBrowse link
G JAG1 jagged canonical Notch ligand 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of JAG1 mRNA CTD PMID:22079614 NCBI chr20:10,637,684...10,673,999
Ensembl chr20:10,637,684...10,673,999 		JBrowse link
G JARID2 jumonji and AT-rich interaction domain containing 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of JARID2 mRNA CTD PMID:20147733 NCBI chr 6:15,246,069...15,522,042
Ensembl chr 6:15,246,069...15,522,042 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of and results in increased phosphorylation of JUN protein CTD PMID:28697429 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G JUND JunD proto-oncogene, AP-1 transcription factor subunit increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of JUND mRNA CTD PMID:22079614 NCBI chr19:18,279,694...18,281,622
Ensembl chr19:18,279,694...18,281,622 		JBrowse link
G KCNC2 potassium voltage-gated channel subfamily C member 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of KCNC2 mRNA CTD PMID:22079614 NCBI chr12:75,040,078...75,209,839
Ensembl chr12:75,040,077...75,209,839 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of KCND2 mRNA CTD PMID:22079614 NCBI chr 7:120,272,908...120,750,337
Ensembl chr 7:120,273,175...120,750,337 		JBrowse link
G KCNE4 potassium voltage-gated channel subfamily E regulatory subunit 4 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of KCNE4 mRNA CTD PMID:22079614 NCBI chr 2:223,052,190...223,055,637
Ensembl chr 2:223,052,190...223,198,399 		JBrowse link
G KCNH6 potassium voltage-gated channel subfamily H member 6 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of KCNH6 mRNA CTD PMID:22079614 NCBI chr17:63,523,358...63,548,992
Ensembl chr17:63,523,334...63,548,977 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of KCNQ1 mRNA CTD PMID:22079614 NCBI chr11:2,445,008...2,849,105
Ensembl chr11:2,444,654...2,849,105 		JBrowse link
G KCTD12 potassium channel tetramerization domain containing 12 multiple interactions
increases expression
decreases expression		 EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of KCTD12 mRNA
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of KCTD12 mRNA
8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of KCTD12 mRNA		 CTD PMID:16997883 PMID:20147733 PMID:22079614 NCBI chr13:76,880,175...76,886,405
Ensembl chr13:76,880,175...76,886,405 		JBrowse link
G KIF5C kinesin family member 5C increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of KIF5C mRNA CTD PMID:22079614 NCBI chr 2:148,875,227...149,026,759
Ensembl chr 2:148,875,227...149,026,759 		JBrowse link
G KIRREL3 kirre like nephrin family adhesion molecule 3 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of KIRREL3 mRNA CTD PMID:22079614 NCBI chr11:126,423,358...127,000,870
Ensembl chr11:126,423,358...127,003,460 		JBrowse link
G KLHL5 kelch like family member 5 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of KLHL5 mRNA CTD PMID:22079614 NCBI chr 4:39,044,827...39,143,101
Ensembl chr 4:39,045,039...39,126,857 		JBrowse link
G KLRC1 killer cell lectin like receptor C1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of KLRC1 mRNA CTD PMID:22079614 NCBI chr12:10,442,264...10,454,685
Ensembl chr12:10,442,264...10,454,685 		JBrowse link
G KLRC2 killer cell lectin like receptor C2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of KLRC2 mRNA CTD PMID:22079614 NCBI chr12:10,430,599...10,436,010
Ensembl chr12:10,426,854...10,442,300 		JBrowse link
G KLRC3 killer cell lectin like receptor C3 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of KLRC3 mRNA CTD PMID:22079614 NCBI chr12:10,412,315...10,420,595
Ensembl chr12:10,412,315...10,420,595 		JBrowse link
G KRT34 keratin 34 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of KRT34 mRNA CTD PMID:20147733 NCBI chr17:41,377,669...41,383,816
Ensembl chr17:41,377,669...41,382,306 		JBrowse link
G KRTAP1-5 keratin associated protein 1-5 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of KRTAP1-5 mRNA CTD PMID:20147733 NCBI chr17:41,026,026...41,027,208
Ensembl chr17:41,026,026...41,027,208 		JBrowse link
G L3MBTL3 L3MBTL histone methyl-lysine binding protein 3 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of L3MBTL3 mRNA CTD PMID:22079614 NCBI chr 6:130,018,581...130,141,438
Ensembl chr 6:130,013,699...130,141,449 		JBrowse link
G LAMA3 laminin subunit alpha 3 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of LAMA3 mRNA CTD PMID:16997883 NCBI chr18:23,689,453...23,955,066
Ensembl chr18:23,689,453...23,956,222 		JBrowse link
G LAMB3 laminin subunit beta 3 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of LAMB3 mRNA CTD PMID:22079614 NCBI chr 1:209,614,870...209,652,425
Ensembl chr 1:209,614,870...209,652,425 		JBrowse link
G LAMP3 lysosomal associated membrane protein 3 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of LAMP3 mRNA CTD PMID:16997883 NCBI chr 3:183,122,215...183,163,813
Ensembl chr 3:183,122,215...183,163,839 		JBrowse link
G LAT2 linker for activation of T cells family member 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of LAT2 mRNA CTD PMID:22079614 NCBI chr 7:74,210,006...74,229,834
Ensembl chr 7:74,199,652...74,229,834 		JBrowse link
G LDLR low density lipoprotein receptor increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of LDLR mRNA CTD PMID:22079614 NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820 		JBrowse link
G LEF1 lymphoid enhancer binding factor 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of LEF1 mRNA CTD PMID:22079614 NCBI chr 4:108,047,548...108,168,932
Ensembl chr 4:108,047,545...108,168,956 		JBrowse link
G LEP leptin multiple interactions
decreases response to substance		 EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [LEP protein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR protein]]; LEP protein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased chemical synthesis of Progesterone]; LEP protein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR protein]; LEPR protein affects the reaction [LEP protein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased chemical synthesis of Progesterone]]; LEPR protein affects the reaction [LEP protein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR protein]]; SB 203580 inhibits the reaction [LEP protein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR protein]]
LEP protein results in decreased susceptibility to 8-Bromo Cyclic Adenosine Monophosphate		 CTD PMID:19849856 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G LEPR leptin receptor multiple interactions EXP LEPR protein affects the reaction [LEP protein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased chemical synthesis of Progesterone]]; LEPR protein affects the reaction [LEP protein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR protein]] CTD PMID:19849856 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559 		JBrowse link
G LGALS1 galectin 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of LGALS1 mRNA CTD PMID:22079614 NCBI chr22:37,675,636...37,679,802
Ensembl chr22:37,675,636...37,679,802 		JBrowse link
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of LGR4 mRNA CTD PMID:20147733 NCBI chr11:27,365,961...27,472,790
Ensembl chr11:27,365,961...27,472,790 		JBrowse link
G LHB luteinizing hormone subunit beta increases expression
multiple interactions		 ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of LHB mRNA; 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of LHB protein
Tetrachlorodibenzodioxin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of LHB mRNA]		 CTD PMID:8404651 PMID:21467749 NCBI chr19:49,015,980...49,019,498
Ensembl chr19:49,015,980...49,017,091 		JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor decreases expression
increases expression
multiple interactions		 EXP
ISO		 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of LHCGR mRNA
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of LHCGR mRNA
T-2 Toxin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of LHCGR mRNA]
Atrazine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of LHCGR mRNA]		 CTD PMID:22079614 PMID:23583632 PMID:30951242 NCBI chr 2:48,686,774...48,755,724
Ensembl chr 2:48,686,774...48,755,730 		JBrowse link
G LIF LIF interleukin 6 family cytokine multiple interactions EXP
ISO		 [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of LIF mRNA
[NR5A1 protein co-treated with LIF protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Tretinoin] results in increased abundance of Progesterone		 CTD PMID:16997883 PMID:21610156 NCBI chr22:30,240,453...30,246,759
Ensembl chr22:30,240,453...30,246,759 		JBrowse link
G LIMCH1 LIM and calponin homology domains 1 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of LIMCH1 mRNA CTD PMID:16997883 NCBI chr 4:41,359,607...41,700,044
Ensembl chr 4:41,359,607...41,700,044 		JBrowse link
G LINGO1 leucine rich repeat and Ig domain containing 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of LINGO1 mRNA CTD PMID:22079614 NCBI chr15:77,613,027...77,820,900
Ensembl chr15:77,613,027...77,820,900 		JBrowse link
G LIPC lipase C, hepatic type increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of LIPC mRNA CTD PMID:22079614 NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844 		JBrowse link
G LMNB1 lamin B1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of LMNB1 mRNA CTD PMID:22079614 NCBI chr 5:126,776,623...126,837,020
Ensembl chr 5:126,776,623...126,837,020 		JBrowse link
G LMO3 LIM domain only 3 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of LMO3 mRNA CTD PMID:16997883 NCBI chr12:16,548,372...16,610,174
Ensembl chr12:16,548,372...16,610,594 		JBrowse link
G LOXL1 lysyl oxidase like 1 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of LOXL1 mRNA CTD PMID:16997883 NCBI chr15:73,926,462...73,952,136
Ensembl chr15:73,925,989...73,952,137 		JBrowse link
G LPCAT1 lysophosphatidylcholine acyltransferase 1 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of LPCAT1 mRNA CTD PMID:16997883 NCBI chr 5:1,461,427...1,523,960
Ensembl chr 5:1,456,480...1,523,962 		JBrowse link
G LPL lipoprotein lipase increases expression
decreases activity		 ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of LPL mRNA
8-Bromo Cyclic Adenosine Monophosphate results in decreased activity of LPL protein		 CTD PMID:9032464 PMID:9414485 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259 		JBrowse link
G LRRC17 leucine rich repeat containing 17 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of LRRC17 mRNA CTD PMID:22079614 NCBI chr 7:102,913,000...102,945,111
Ensembl chr 7:102,913,000...102,945,111 		JBrowse link
G LSS lanosterol synthase decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of LSS mRNA CTD PMID:22079614 NCBI chr21:46,188,446...46,228,774
Ensembl chr21:46,188,141...46,228,824 		JBrowse link
G LUM lumican increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of LUM mRNA CTD PMID:22079614 NCBI chr12:91,102,629...91,111,494
Ensembl chr12:91,102,629...91,111,494 		JBrowse link
G LXN latexin multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of LXN mRNA CTD PMID:16997883 NCBI chr 3:158,666,414...158,672,648
Ensembl chr 3:158,645,822...158,672,648 		JBrowse link
G LYPD1 LY6/PLAUR domain containing 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of LYPD1 mRNA CTD PMID:20147733 NCBI chr 2:132,643,286...132,671,526
Ensembl chr 2:132,643,286...132,671,579 		JBrowse link
G LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of XLKD1 mRNA CTD PMID:22079614 NCBI chr11:10,556,966...10,568,665
Ensembl chr11:10,556,966...10,611,689 		JBrowse link
G MAGEB10 MAGE family member B10 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of MAGEB10 mRNA CTD PMID:22079614 NCBI chr  X:27,807,990...27,823,014
Ensembl chr  X:27,807,990...27,823,014 		JBrowse link
G MAMDC2 MAM domain containing 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of MAMDC2 mRNA CTD PMID:22079614 NCBI chr 9:70,043,581...70,226,972
Ensembl chr 9:70,043,848...70,226,972 		JBrowse link
G MAN1A1 mannosidase alpha class 1A member 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of MAN1A1 mRNA CTD PMID:22079614 NCBI chr 6:119,177,205...119,350,605
Ensembl chr 6:119,177,205...119,349,761 		JBrowse link
G MAP3K8 mitogen-activated protein kinase kinase kinase 8 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of MAP3K8 mRNA CTD PMID:22079614 NCBI chr10:30,434,021...30,461,833
Ensembl chr10:30,434,021...30,461,833 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions EXP
ISO		 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased activity of MAPK1 protein]; [1-Methyl-3-isobutylxanthine co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased activity of MAPK1 protein
[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of and results in increased activity of MAPK1 protein; azalanstat inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; EGF protein inhibits the reaction [naphthol AS-E phosphate inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; naphthol AS-E phosphate inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of and results in increased activity of MAPK1 protein]
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased phosphorylation of MAPK1 protein]		 CTD PMID:8526880 PMID:12657697 PMID:18467523 PMID:19252090 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK10 mitogen-activated protein kinase 10 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of MAPK10 mRNA CTD PMID:22079614 NCBI chr 4:86,010,405...86,594,074
Ensembl chr 4:85,990,007...86,594,625 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
decreases expression		 EXP
ISO		 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased activity of MAPK3 protein]; [1-Methyl-3-isobutylxanthine co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased activity of MAPK3 protein
[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of and results in increased activity of MAPK3 protein; azalanstat inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; EGF protein inhibits the reaction [naphthol AS-E phosphate inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; naphthol AS-E phosphate inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of and results in increased activity of MAPK3 protein]
8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of MAPK3 mRNA
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased phosphorylation of MAPK3 protein]		 CTD PMID:8526880 PMID:12657697 PMID:18467523 PMID:19252090 PMID:22079614 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPT microtubule associated protein tau decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of MAPT mRNA CTD PMID:22079614 NCBI chr17:45,894,554...46,028,334
Ensembl chr17:45,894,527...46,028,334 		JBrowse link
G MC2R melanocortin 2 receptor increases expression
multiple interactions		 EXP
ISO		 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of MC2R mRNA
[20-hydroxycholesterol co-treated with Tretinoin co-treated with 8-Bromo Cyclic Adenosine Monophosphate] promotes the reaction [NR5A1 protein binds to MC2R promoter]		 CTD PMID:21610156 PMID:22079614 NCBI chr18:13,882,044...13,915,707
Ensembl chr18:13,882,044...13,915,707 		JBrowse link
G MCF2 MCF.2 cell line derived transforming sequence decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of MCF2 mRNA CTD PMID:22079614 NCBI chr  X:139,581,770...139,708,167
Ensembl chr  X:139,581,770...139,708,216 		JBrowse link
G MCF2L MCF.2 cell line derived transforming sequence like decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of MCF2L mRNA CTD PMID:22079614 NCBI chr13:112,894,335...113,099,742
Ensembl chr13:112,894,378...113,099,742 		JBrowse link
G MDH1 malate dehydrogenase 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of MDH1 mRNA CTD PMID:22079614 NCBI chr 2:63,588,963...63,607,197
Ensembl chr 2:63,588,609...63,607,197 		JBrowse link
G MEDAG mesenteric estrogen dependent adipogenesis increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of MEDAG mRNA CTD PMID:20147733 NCBI chr13:30,906,271...30,925,572
Ensembl chr13:30,906,271...30,925,572 		JBrowse link
G MERTK MER proto-oncogene, tyrosine kinase decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of MERTK mRNA CTD PMID:22079614 NCBI chr 2:111,898,607...112,029,561
Ensembl chr 2:111,898,607...112,029,561 		JBrowse link
G METRNL meteorin like, glial cell differentiation regulator increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of METRNL mRNA CTD PMID:22079614 NCBI chr17:83,079,609...83,095,122
Ensembl chr17:83,079,609...83,095,122 		JBrowse link
G MGST1 microsomal glutathione S-transferase 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of MGST1 mRNA CTD PMID:22079614 NCBI chr12:16,347,115...16,593,331
Ensembl chr12:16,347,142...16,609,259 		JBrowse link
G MIA2 MIA SH3 domain ER export factor 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of MIA2 mRNA CTD PMID:22079614 NCBI chr14:39,233,915...39,388,522
Ensembl chr14:39,230,231...39,388,513 		JBrowse link
G MICB MHC class I polypeptide-related sequence B increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of MICB mRNA CTD PMID:22079614 NCBI chr 6:31,494,918...31,511,124
Ensembl chr 6:31,494,881...31,511,124 		JBrowse link
G MILR1 mast cell immunoglobulin like receptor 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of MILR1 mRNA CTD PMID:20147733 NCBI chr17:64,449,115...64,497,356
Ensembl chr17:64,449,037...64,468,643 		JBrowse link
G MME membrane metalloendopeptidase decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of MME mRNA CTD PMID:22079614 NCBI chr 3:155,024,202...155,183,729
Ensembl chr 3:155,024,124...155,183,704 		JBrowse link
G MMP10 matrix metallopeptidase 10 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of MMP10 mRNA CTD PMID:22079614 NCBI chr11:102,770,502...102,780,628
Ensembl chr11:102,770,502...102,780,628 		JBrowse link
G MMP16 matrix metallopeptidase 16 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of MMP16 mRNA CTD PMID:20147733 NCBI chr 8:88,032,011...88,327,483
Ensembl chr 8:88,032,011...88,328,025 		JBrowse link
G MOB4 MOB family member 4, phocein increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of MOB4 mRNA CTD PMID:22079614 NCBI chr 2:197,515,554...197,553,699
Ensembl chr 2:197,515,571...197,553,699 		JBrowse link
G MOCOS molybdenum cofactor sulfurase increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of MOCOS mRNA CTD PMID:22079614 NCBI chr18:36,187,497...36,272,157
Ensembl chr18:36,187,497...36,272,157 		JBrowse link
G MOXD1 monooxygenase DBH like 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of MOXD1 mRNA CTD PMID:22079614 NCBI chr 6:132,296,055...132,401,475
Ensembl chr 6:132,296,055...132,401,475 		JBrowse link
G MPP3 MAGUK p55 scaffold protein 3 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of MPP3 mRNA CTD PMID:22079614 NCBI chr17:43,800,811...43,833,146
Ensembl chr17:43,800,799...43,833,170 		JBrowse link
G MRAP melanocortin 2 receptor accessory protein decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of MRAP mRNA CTD PMID:22079614 NCBI chr21:32,291,813...32,314,784
Ensembl chr21:32,291,813...32,314,784 		JBrowse link
G MRAS muscle RAS oncogene homolog increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of MRAS mRNA CTD PMID:22079614 NCBI chr 3:138,347,648...138,405,535
Ensembl chr 3:138,347,648...138,405,534 		JBrowse link
G MSMO1 methylsterol monooxygenase 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of MSMO1 mRNA CTD PMID:22079614 NCBI chr 4:165,327,669...165,343,164
Ensembl chr 4:165,327,667...165,343,164 		JBrowse link
G MSRB3 methionine sulfoxide reductase B3 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of MSRB3 mRNA CTD PMID:22079614 NCBI chr12:65,278,683...65,466,907
Ensembl chr12:65,278,643...65,491,430 		JBrowse link
G MTMR4 myotubularin related protein 4 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of MTMR4 mRNA CTD PMID:20147733 NCBI chr17:58,489,537...58,519,047
Ensembl chr17:58,489,529...58,517,905 		JBrowse link
G MTSS1 MTSS I-BAR domain containing 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of MTSS1 mRNA CTD PMID:22079614 NCBI chr 8:124,550,784...124,728,473
Ensembl chr 8:124,550,784...124,728,473 		JBrowse link
G MUC1 mucin 1, cell surface associated multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of MUC1 mRNA CTD PMID:16997883 NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916 		JBrowse link
G MVD mevalonate diphosphate decarboxylase increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of MVD mRNA CTD PMID:22079614 NCBI chr16:88,651,940...88,663,091
Ensembl chr16:88,651,935...88,663,161 		JBrowse link
G MVK mevalonate kinase increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of MVK mRNA CTD PMID:22079614 NCBI chr12:109,573,272...109,598,125
Ensembl chr12:109,573,255...109,598,125 		JBrowse link
G MYB MYB proto-oncogene, transcription factor decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of MYB mRNA CTD PMID:22079614 NCBI chr 6:135,181,308...135,219,172
Ensembl chr 6:135,181,308...135,219,173 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of MYC mRNA CTD PMID:22079614 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G MYH7B myosin heavy chain 7B decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of MYH7B mRNA CTD PMID:22079614 NCBI chr20:34,955,868...35,002,437
Ensembl chr20:34,955,810...35,002,437 		JBrowse link
G MYLIP myosin regulatory light chain interacting protein decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of MYLIP mRNA CTD PMID:22079614 NCBI chr 6:16,129,086...16,163,887
Ensembl chr 6:16,129,086...16,148,248 		JBrowse link
G MYOF myoferlin increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of MYOF mRNA CTD PMID:22079614 NCBI chr10:93,306,429...93,482,334
Ensembl chr10:93,306,429...93,482,334 		JBrowse link
G MYPN myopalladin increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of MYPN mRNA CTD PMID:22079614 NCBI chr10:68,087,897...68,212,017
Ensembl chr10:68,087,897...68,212,017 		JBrowse link
G N4BP2L1 NEDD4 binding protein 2 like 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of N4BP2L1 mRNA CTD PMID:22079614 NCBI chr13:32,400,723...32,429,615
Ensembl chr13:32,400,723...32,428,311 		JBrowse link
G NALF1 NALCN channel auxiliary factor 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NALF1 mRNA CTD PMID:22079614 NCBI chr13:107,163,510...107,867,496
Ensembl chr13:107,163,510...107,867,496 		JBrowse link
G NANOS1 nanos C2HC-type zinc finger 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NANOS1 mRNA CTD PMID:22079614 NCBI chr10:119,029,714...119,033,730
Ensembl chr10:119,029,714...119,033,730 		JBrowse link
G NAP1L2 nucleosome assembly protein 1 like 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of NAP1L2 mRNA CTD PMID:22079614 NCBI chr  X:73,212,299...73,214,851
Ensembl chr  X:73,212,299...73,214,851 		JBrowse link
G NAV3 neuron navigator 3 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of NAV3 mRNA CTD PMID:22079614 NCBI chr12:77,571,862...78,213,010
Ensembl chr12:77,324,641...78,213,010 		JBrowse link
G NCF2 neutrophil cytosolic factor 2 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of NCF2 mRNA CTD PMID:16997883 NCBI chr 1:183,555,562...183,601,849
Ensembl chr 1:183,554,461...183,590,905 		JBrowse link
G NECTIN3 nectin cell adhesion molecule 3 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NECTIN3 mRNA CTD PMID:22079614 NCBI chr 3:111,071,816...111,194,170
Ensembl chr 3:111,070,071...111,275,563 		JBrowse link
G NEK6 NIMA related kinase 6 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NEK6 mRNA CTD PMID:22079614 NCBI chr 9:124,257,606...124,353,307
Ensembl chr 9:124,257,606...124,353,307 		JBrowse link
G NGEF neuronal guanine nucleotide exchange factor increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NGEF mRNA CTD PMID:22079614 NCBI chr 2:232,878,701...233,013,256
Ensembl chr 2:232,878,701...233,013,256 		JBrowse link
G NGF nerve growth factor decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of NGF mRNA CTD PMID:22079614 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770 		JBrowse link
G NIBAN1 niban apoptosis regulator 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NIBAN1 mRNA CTD PMID:22079614 NCBI chr 1:184,791,032...184,974,508
Ensembl chr 1:184,790,724...184,974,508 		JBrowse link
G NID2 nidogen 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NID2 mRNA CTD PMID:20147733 NCBI chr14:52,004,809...52,069,059
Ensembl chr14:52,004,809...52,069,059 		JBrowse link
G NKX2-1 NK2 homeobox 1 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of NKX2-1 mRNA CTD PMID:16997883 NCBI chr14:36,516,397...36,520,232
Ensembl chr14:36,516,392...36,521,149 		JBrowse link
G NLGN4Y neuroligin 4 Y-linked increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NLGN4Y mRNA CTD PMID:22079614 NCBI chr  Y:14,522,616...14,845,654
Ensembl chr  Y:14,522,573...14,845,654 		JBrowse link
G NMU neuromedin U increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NMU mRNA CTD PMID:23423171 NCBI chr 4:55,595,231...55,636,793
Ensembl chr 4:55,595,229...55,636,698 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [ochratoxin A results in increased expression of NOS2 mRNA] CTD PMID:15994020 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOTCH3 notch receptor 3 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NOTCH3 mRNA CTD PMID:20147733 NCBI chr19:15,159,038...15,200,995
Ensembl chr19:15,159,038...15,200,995 		JBrowse link
G NR1D1 nuclear receptor subfamily 1 group D member 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of NR1D1 mRNA CTD PMID:22079614 NCBI chr17:40,092,793...40,100,589
Ensembl chr17:40,092,793...40,100,589 		JBrowse link
G NR1D2 nuclear receptor subfamily 1 group D member 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of NR1D2 mRNA CTD PMID:22079614 NCBI chr 3:23,945,286...23,980,617
Ensembl chr 3:23,945,286...23,980,617 		JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of NR1H2 mRNA CTD PMID:22079614 NCBI chr19:50,376,457...50,383,388
Ensembl chr19:50,329,653...50,383,388 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 multiple interactions ISO 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Ethinyl Estradiol results in decreased expression of NR1H4 mRNA]; 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Ethinyl Estradiol results in decreased expression of NR1H4 protein] CTD PMID:27743861 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414 		JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NR1I2 mRNA CTD PMID:22079614 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487 		JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NR1I3 mRNA CTD PMID:22079614 NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 multiple interactions EXP [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in decreased expression of NR3C1 mRNA; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in decreased expression of NR3C1 protein; [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in decreased expression of NR3C1 protein; [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in decreased expression of NR3C1 mRNA; NR3C1 protein inhibits the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in decreased expression of GRIA1 mRNA]; NR3C1 protein inhibits the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of ZNF486 mRNA]; NR3C1 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of WNT4 mRNA] CTD PMID:23275455 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512 		JBrowse link
G NR3C2 nuclear receptor subfamily 3 group C member 2 increases expression
multiple interactions		 EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NR3C2 mRNA
[Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of NR3C2 mRNA; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of NR3C2 mRNA; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of NR3C2 protein; [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of NR3C2 protein; [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of NR3C2 mRNA; NR3C2 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in decreased expression of GRIA1 mRNA]; NR3C2 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of DHRS3 mRNA]; NR3C2 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of FBXO32 mRNA]		 CTD PMID:22079614 PMID:23275455 NCBI chr 4:148,078,764...148,445,508
Ensembl chr 4:148,078,762...148,444,698 		JBrowse link
G NR4A1 nuclear receptor subfamily 4 group A member 1 increases expression ISO
EXP		 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NR4A1 protein
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NR4A1 mRNA		 CTD PMID:21726595 PMID:22079614 NCBI chr12:52,022,832...52,059,503
Ensembl chr12:52,022,832...52,059,507 		JBrowse link
G NR4A2 nuclear receptor subfamily 4 group A member 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NR4A2 mRNA CTD PMID:22079614 NCBI chr 2:156,324,437...156,332,721
Ensembl chr 2:156,324,437...156,342,348 		JBrowse link
G NR4A3 nuclear receptor subfamily 4 group A member 3 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NR4A3 mRNA CTD PMID:22079614 NCBI chr 9:99,821,885...99,866,891
Ensembl chr 9:99,821,855...99,866,891 		JBrowse link
G NR5A1 nuclear receptor subfamily 5 group A member 1 multiple interactions ISO [20-hydroxycholesterol co-treated with Tretinoin co-treated with 8-Bromo Cyclic Adenosine Monophosphate] promotes the reaction [NR5A1 protein binds to MC2R promoter]; [NR5A1 protein co-treated with 20-hydroxycholesterol co-treated with Tretinoin co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased abundance of Progesterone; [NR5A1 protein co-treated with 20-hydroxycholesterol co-treated with Tretinoin co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP11A1 mRNA; [NR5A1 protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate] affects the expression of HSD17B2 mRNA; [NR5A1 protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased abundance of Estradiol; [NR5A1 protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased abundance of Progesterone; [NR5A1 protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased abundance of Testosterone; [NR5A1 protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP11A1 mRNA; [NR5A1 protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP11B1 mRNA; [NR5A1 protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP17A1 mRNA; [NR5A1 protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP19A1 mRNA; [NR5A1 protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP21A1 mRNA; [NR5A1 protein co-treated with LIF protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Tretinoin] results in increased abundance of Progesterone CTD PMID:21610156 NCBI chr 9:124,481,236...124,507,399
Ensembl chr 9:124,481,236...124,507,420 		JBrowse link
G NRCAM neuronal cell adhesion molecule decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of NRCAM mRNA CTD PMID:22079614 NCBI chr 7:108,147,649...108,456,720
Ensembl chr 7:108,147,623...108,456,717 		JBrowse link
G NRP1 neuropilin 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NRP1 mRNA CTD PMID:22079614 NCBI chr10:33,177,493...33,334,667
Ensembl chr10:33,177,492...33,336,262 		JBrowse link
G NTF4 neurotrophin 4 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of NTF5 mRNA CTD PMID:22079614 NCBI chr19:49,058,284...49,065,035
Ensembl chr19:49,061,066...49,065,076 		JBrowse link
G NUDT10 nudix hydrolase 10 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of NUDT10 mRNA CTD PMID:22079614 NCBI chr  X:51,332,231...51,337,525
Ensembl chr  X:51,332,231...51,337,525 		JBrowse link
G NXN nucleoredoxin increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NXN mRNA CTD PMID:22079614 NCBI chr17:799,310...979,776
Ensembl chr17:799,310...979,776 		JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of OGT mRNA CTD PMID:22079614 NCBI chr  X:71,533,104...71,575,892
Ensembl chr  X:71,533,087...71,575,892 		JBrowse link
G OMG oligodendrocyte myelin glycoprotein increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of OMG mRNA CTD PMID:22079614 NCBI chr17:31,294,647...31,297,239
Ensembl chr17:31,272,013...31,297,539 		JBrowse link
G OSBP2 oxysterol binding protein 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of OSBP2 mRNA CTD PMID:22079614 NCBI chr22:30,693,782...30,907,813
Ensembl chr22:30,693,782...30,907,824 		JBrowse link
G OSTF1 osteoclast stimulating factor 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of OSTF1 mRNA CTD PMID:22079614 NCBI chr 9:75,088,514...75,147,265
Ensembl chr 9:75,088,514...75,147,265 		JBrowse link
G OXGR1 oxoglutarate receptor 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of OXGR1 mRNA CTD PMID:22079614 NCBI chr13:96,985,713...96,994,730
Ensembl chr13:96,985,713...96,994,730 		JBrowse link
G P4HA3 prolyl 4-hydroxylase subunit alpha 3 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of P4HA3 mRNA CTD PMID:20147733 NCBI chr11:74,250,146...74,311,640
Ensembl chr11:74,235,801...74,311,640 		JBrowse link
G PALM2AKAP2 PALM2 and AKAP2 fusion increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PALM2AKAP2 mRNA CTD PMID:22079614 NCBI chr 9:109,640,787...110,172,512
Ensembl chr 9:109,498,325...110,172,512 		JBrowse link
G PALMD palmdelphin increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PALMD mRNA CTD PMID:20147733 NCBI chr 1:99,646,113...99,694,535
Ensembl chr 1:99,646,113...99,694,541 		JBrowse link
G PAPPA pappalysin 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PAPPA mRNA CTD PMID:20147733 NCBI chr 9:116,153,791...116,402,321
Ensembl chr 9:116,153,791...116,402,321 		JBrowse link
G PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PAPSS2 mRNA CTD PMID:22079614 NCBI chr10:87,659,878...87,747,705
Ensembl chr10:87,659,613...87,747,705 		JBrowse link
G PAQR5 progestin and adipoQ receptor family member 5 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PAQR5 mRNA CTD PMID:20147733 NCBI chr15:69,298,912...69,407,780
Ensembl chr15:69,298,912...69,407,780 		JBrowse link
G PATJ PATJ crumbs cell polarity complex component increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PATJ mRNA CTD PMID:22079614 NCBI chr 1:61,742,480...62,163,915
Ensembl chr 1:61,742,477...62,178,675 		JBrowse link
G PBX4 PBX homeobox 4 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PBX4 mRNA CTD PMID:22079614 NCBI chr19:19,561,713...19,618,687
Ensembl chr19:19,561,707...19,618,693 		JBrowse link
G PCDH20 protocadherin 20 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PCDH20 mRNA CTD PMID:22079614 NCBI chr13:61,409,685...61,415,849
Ensembl chr13:61,409,685...61,415,849 		JBrowse link
G PCDHB4 protocadherin beta 4 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PCDHB4 mRNA CTD PMID:20147733 NCBI chr 5:141,121,818...141,125,623
Ensembl chr 5:141,121,818...141,125,623 		JBrowse link
G PCSK1 proprotein convertase subtilisin/kexin type 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PCSK1 mRNA CTD PMID:20147733 PMID:22079614 NCBI chr 5:96,390,333...96,433,248
Ensembl chr 5:96,390,333...96,434,143 		JBrowse link
G PDE1A phosphodiesterase 1A increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PDE1A mRNA CTD PMID:20147733 NCBI chr 2:182,140,041...182,716,797
Ensembl chr 2:182,139,968...182,523,359 		JBrowse link
G PDE2A phosphodiesterase 2A decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PDE2A mRNA CTD PMID:22079614 NCBI chr11:72,576,141...72,674,422
Ensembl chr11:72,576,141...72,674,591 		JBrowse link
G PDE3A phosphodiesterase 3A increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PDE3A mRNA CTD PMID:12466227 NCBI chr12:20,368,537...20,688,583
Ensembl chr12:20,368,537...20,688,583 		JBrowse link
G PDGFD platelet derived growth factor D decreases expression
increases expression		 EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PDGFD mRNA
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PDGFD mRNA		 CTD PMID:20147733 PMID:22079614 NCBI chr11:103,907,189...104,164,147
Ensembl chr11:103,907,189...104,164,379 		JBrowse link
G PDLIM4 PDZ and LIM domain 4 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of PDLIM4 mRNA CTD PMID:16997883 NCBI chr 5:132,257,696...132,273,454
Ensembl chr 5:132,257,696...132,273,454 		JBrowse link
G PDZRN3 PDZ domain containing ring finger 3 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PDZRN3 mRNA CTD PMID:22079614 NCBI chr 3:73,382,431...73,624,941
Ensembl chr 3:73,382,431...73,624,941 		JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PECAM1 mRNA CTD PMID:16997883 NCBI chr17:64,319,415...64,390,860
Ensembl chr17:64,319,415...64,413,776 		JBrowse link
G PEG10 paternally expressed 10 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PEG10 mRNA CTD PMID:20147733 NCBI chr 7:94,656,325...94,669,695
Ensembl chr 7:94,656,325...94,669,695 		JBrowse link
G PGM5 phosphoglucomutase 5 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PGM5 mRNA CTD PMID:22079614 NCBI chr 9:68,356,611...68,531,061
Ensembl chr 9:68,328,308...68,531,061 		JBrowse link
G PGR progesterone receptor multiple interactions
decreases expression		 EXP [8-Bromo Cyclic Adenosine Monophosphate co-treated with Progesterone co-treated with Estradiol] affects the expression of and affects the phosphorylation of PGR protein
8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PGR protein		 CTD PMID:23275455 NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813 		JBrowse link
G PHACTR3 phosphatase and actin regulator 3 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PHACTR3 mRNA CTD PMID:22079614 NCBI chr20:59,577,509...59,847,711
Ensembl chr20:59,577,509...59,847,711 		JBrowse link
G PHAF1 phagosome assembly factor 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PHAF1 mRNA CTD PMID:22079614 NCBI chr16:67,109,941...67,148,544
Ensembl chr16:67,109,941...67,148,544 		JBrowse link
G PID1 phosphotyrosine interaction domain containing 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PID1 mRNA CTD PMID:20147733 NCBI chr 2:229,023,973...229,271,287
Ensembl chr 2:228,850,526...229,271,287 		JBrowse link
G PIK3R3 phosphoinositide-3-kinase regulatory subunit 3 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PIK3R3 mRNA CTD PMID:22079614 NCBI chr 1:46,040,140...46,174,901
Ensembl chr 1:46,040,140...46,133,036 		JBrowse link
G PITPNC1 phosphatidylinositol transfer protein cytoplasmic 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PITPNC1 mRNA CTD PMID:20147733 NCBI chr17:67,377,281...67,697,256
Ensembl chr17:67,377,281...67,697,256 		JBrowse link
G PLA2R1 phospholipase A2 receptor 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PLA2R1 mRNA CTD PMID:22079614 NCBI chr 2:159,923,933...160,062,615
Ensembl chr 2:159,932,006...160,062,615 		JBrowse link
G PLAT plasminogen activator, tissue type increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PLAT mRNA CTD PMID:20147733 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709 		JBrowse link
G PLCB1 phospholipase C beta 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PLCB1 mRNA CTD PMID:20147733 NCBI chr20:8,132,266...8,884,900
Ensembl chr20:8,077,251...8,968,360 		JBrowse link
G PLD1 phospholipase D1 multiple interactions EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of and results in increased activity of PLD1 protein; PLD1 protein affects the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IGFBP1 mRNA]; PLD1 protein affects the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PRL mRNA] CTD PMID:17065600 NCBI chr 3:171,600,404...171,810,483
Ensembl chr 3:171,600,404...171,810,950 		JBrowse link
G PMEPA1 prostate transmembrane protein, androgen induced 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PMEPA1 mRNA CTD PMID:22079614 NCBI chr20:57,648,396...57,711,472
Ensembl chr20:57,648,392...57,711,536 		JBrowse link
G PON3 paraoxonase 3 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PON3 mRNA CTD PMID:22079614 NCBI chr 7:95,359,872...95,396,375
Ensembl chr 7:95,359,872...95,396,375 		JBrowse link
G POU3F1 POU class 3 homeobox 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of POU3F1 mRNA CTD PMID:22079614 NCBI chr 1:38,043,829...38,046,793
Ensembl chr 1:38,043,829...38,046,793 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PPARA mRNA CTD PMID:22079614 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma decreases expression
multiple interactions		 ISO 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PPARG mRNA
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [ochratoxin A results in increased expression of PPARG mRNA]		 CTD PMID:15994020 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PPFIBP1 PPFIA binding protein 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PPFIBP1 mRNA CTD PMID:22079614 NCBI chr12:27,524,206...27,695,564
Ensembl chr12:27,523,431...27,695,564 		JBrowse link
G PPM1H protein phosphatase, Mg2+/Mn2+ dependent 1H decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PPM1H mRNA CTD PMID:22079614 NCBI chr12:62,643,994...62,935,150
Ensembl chr12:62,643,994...62,935,150 		JBrowse link
G PPP1R3C protein phosphatase 1 regulatory subunit 3C increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PPP1R3C mRNA CTD PMID:20147733 NCBI chr10:91,628,442...91,633,071
Ensembl chr10:91,628,442...91,633,071 		JBrowse link
G PRKACB protein kinase cAMP-activated catalytic subunit beta multiple interactions EXP [PRKACB protein mutant form results in increased susceptibility to 8-Bromo Cyclic Adenosine Monophosphate analog] results in decreased stability of [PRKACB protein mutant form binds to PRKAR1A protein] CTD PMID:29669941 NCBI chr 1:84,078,079...84,238,498
Ensembl chr 1:84,078,062...84,238,498 		JBrowse link
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha multiple interactions EXP [PRKACB protein mutant form results in increased susceptibility to 8-Bromo Cyclic Adenosine Monophosphate analog] results in decreased stability of [PRKACB protein mutant form binds to PRKAR1A protein] CTD PMID:29669941 NCBI chr17:68,413,623...68,551,316
Ensembl chr17:68,511,780...68,551,319 		JBrowse link
G PRKAR2B protein kinase cAMP-dependent type II regulatory subunit beta increases expression
multiple interactions		 EXP
ISO		 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PRKAR2B mRNA
[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of PRKAR2B protein		 CTD PMID:18467523 PMID:22079614 NCBI chr 7:107,044,705...107,161,811
Ensembl chr 7:107,044,705...107,161,811 		JBrowse link
G PRKCA protein kinase C alpha increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PRKCA mRNA CTD PMID:22079614 NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743 		JBrowse link
G PRL prolactin multiple interactions
increases expression
decreases expression
increases secretion		 EXP
ISO		 1-Butanol inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PRL mRNA]; [8-Bromo Cyclic Adenosine Monophosphate co-treated with Dexamethasone] results in increased expression of PRL mRNA; [8-Bromo Cyclic Adenosine Monophosphate co-treated with Medroxyprogesterone Acetate] results in increased expression of PRL mRNA; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased secretion of PRL protein; EZH2 mutant form inhibits the reaction [[8-Bromo Cyclic Adenosine Monophosphate co-treated with Medroxyprogesterone Acetate] results in increased expression of PRL mRNA]; FOXO1 protein affects the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased secretion of PRL protein]; PLD1 protein affects the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PRL mRNA]; Progesterone promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PRL mRNA]; Tobacco Smoke Pollution inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PRL mRNA]
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PRL mRNA; 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PRL protein
8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PRL mRNA; 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PRL protein
8-Bromo Cyclic Adenosine Monophosphate results in increased secretion of PRL protein		 CTD PMID:15774544 PMID:16709600 PMID:17065600 PMID:18815356 PMID:20147733 More... NCBI chr 6:22,287,246...22,302,835
Ensembl chr 6:22,287,244...22,302,826 		JBrowse link
G PRMT7 protein arginine methyltransferase 7 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PRMT7 mRNA CTD PMID:22079614 NCBI chr16:68,311,019...68,360,870
Ensembl chr16:68,310,951...68,360,852 		JBrowse link
G PRSS23 serine protease 23 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PRSS23 mRNA CTD PMID:22079614 NCBI chr11:86,791,071...86,952,910
Ensembl chr11:86,791,059...86,952,910 		JBrowse link
G PSAT1 phosphoserine aminotransferase 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PSAT1 mRNA CTD PMID:22079614 NCBI chr 9:78,297,125...78,330,093
Ensembl chr 9:78,297,125...78,330,093 		JBrowse link
G PSG4 pregnancy specific beta-1-glycoprotein 4 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PSG4 mRNA CTD PMID:20147733 NCBI chr19:43,192,702...43,205,638
Ensembl chr19:43,192,702...43,207,299 		JBrowse link
G PSG7 pregnancy specific beta-1-glycoprotein 7 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PSG7 mRNA CTD PMID:20147733 NCBI chr19:42,924,132...42,937,207
Ensembl chr19:42,924,132...42,937,207 		JBrowse link
G PTGDR2 prostaglandin D2 receptor 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PTGDR2 mRNA CTD PMID:22079614 NCBI chr11:60,850,933...60,855,950
Ensembl chr11:60,850,933...60,855,950 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PTGS1 mRNA CTD PMID:22079614 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP 8-Bromo Cyclic Adenosine Monophosphate promotes the reaction [IL1B protein results in increased expression of PTGS2 protein]; [PTGS2 co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of VEGFA CTD PMID:11112151 PMID:12821125 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTH parathyroid hormone increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PTH mRNA CTD PMID:22079614 NCBI chr11:13,492,054...13,496,181
Ensembl chr11:13,492,054...13,496,181 		JBrowse link
G PTHLH parathyroid hormone like hormone increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PTHLH mRNA CTD PMID:20147733 NCBI chr12:27,958,084...27,972,733
Ensembl chr12:27,958,084...27,972,733 		JBrowse link
G PTK2 protein tyrosine kinase 2 multiple interactions ISO 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [HU 211 results in increased phosphorylation of PTK2 protein] CTD PMID:12163181 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216 		JBrowse link
G PTP4A1 protein tyrosine phosphatase 4A1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PTP4A1 mRNA CTD PMID:22079614 NCBI chr 6:63,516,440...63,583,588
Ensembl chr 6:63,521,746...63,583,588 		JBrowse link
G PTPRE protein tyrosine phosphatase receptor type E increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PTPRE mRNA CTD PMID:22079614 NCBI chr10:127,907,103...128,085,855
Ensembl chr10:127,907,103...128,085,855 		JBrowse link
G PTPRF protein tyrosine phosphatase receptor type F decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PTPRF mRNA CTD PMID:22079614 NCBI chr 1:43,522,051...43,623,666
Ensembl chr 1:43,525,187...43,623,666 		JBrowse link
G PTPRZ1 protein tyrosine phosphatase receptor type Z1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PTPRZ1 mRNA CTD PMID:22079614 NCBI chr 7:121,873,161...122,062,036
Ensembl chr 7:121,873,089...122,062,036 		JBrowse link
G PTS 6-pyruvoyltetrahydropterin synthase increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PTS mRNA CTD PMID:22079614 NCBI chr11:112,226,428...112,233,973
Ensembl chr11:112,226,367...112,269,955 		JBrowse link
G PXYLP1 2-phosphoxylose phosphatase 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PXYLP1 mRNA CTD PMID:22079614 NCBI chr 3:141,231,825...141,294,924
Ensembl chr 3:141,228,726...141,367,753 		JBrowse link
G PYGL glycogen phosphorylase L decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PYGL mRNA CTD PMID:22079614 NCBI chr14:50,905,217...50,944,483
Ensembl chr14:50,857,891...50,944,483 		JBrowse link
G PZP PZP alpha-2-macroglobulin like increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PZP mRNA CTD PMID:22079614 NCBI chr12:9,136,472...9,208,395
Ensembl chr12:9,148,840...9,208,395 		JBrowse link
G RAB25 RAB25, member RAS oncogene family decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of RAB25 mRNA CTD PMID:22079614 NCBI chr 1:156,061,160...156,070,504
Ensembl chr 1:156,061,160...156,070,504 		JBrowse link
G RAB27B RAB27B, member RAS oncogene family increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of RAB27B mRNA CTD PMID:20147733 NCBI chr18:54,717,857...54,895,516
Ensembl chr18:54,717,860...54,895,516 		JBrowse link
G RABGAP1 RAB GTPase activating protein 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of RABGAP1 mRNA CTD PMID:22079614 NCBI chr 9:122,931,671...123,104,866
Ensembl chr 9:122,940,833...123,104,866 		JBrowse link
G RAN RAN, member RAS oncogene family increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of RAN mRNA CTD PMID:22079614 NCBI chr12:130,872,066...130,877,678
Ensembl chr12:130,872,037...130,877,678 		JBrowse link
G RAP1A RAP1A, member of RAS oncogene family increases activity ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased activity of RAP1A protein CTD PMID:10908723 NCBI chr 1:111,542,009...111,716,691
Ensembl chr 1:111,542,218...111,716,691 		JBrowse link
G RAP1B RAP1B, member of RAS oncogene family increases activity ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased activity of RAP1B protein CTD PMID:10908723 NCBI chr12:68,610,899...68,671,901
Ensembl chr12:68,610,855...68,671,901 		JBrowse link
G RARG retinoic acid receptor gamma increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of RARG mRNA CTD PMID:22079614 NCBI chr12:53,210,569...53,232,209
Ensembl chr12:53,210,567...53,232,980 		JBrowse link
G RARRES2 retinoic acid receptor responder 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of RARRES2 mRNA CTD PMID:22079614 NCBI chr 7:150,338,329...150,341,629
Ensembl chr 7:150,338,317...150,341,662 		JBrowse link
G RASD1 ras related dexamethasone induced 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of RASD1 mRNA CTD PMID:20147733 NCBI chr17:17,494,437...17,496,395
Ensembl chr17:17,494,437...17,496,395 		JBrowse link
G RASIP1 Ras interacting protein 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of RASIP1 mRNA CTD PMID:22079614 NCBI chr19:48,720,585...48,740,610
Ensembl chr19:48,720,585...48,740,610 		JBrowse link
G RASSF5 Ras association domain family member 5 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of RASSF5 mRNA CTD PMID:22079614 NCBI chr 1:206,507,531...206,589,448
Ensembl chr 1:206,507,531...206,589,448 		JBrowse link
G RASSF6 Ras association domain family member 6 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of RASSF6 mRNA CTD PMID:22079614 NCBI chr 4:73,571,550...73,620,631
Ensembl chr 4:73,571,550...73,620,631 		JBrowse link
G RBMS3 RNA binding motif single stranded interacting protein 3 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of RBMS3 mRNA CTD PMID:22079614 NCBI chr 3:29,281,071...30,010,395
Ensembl chr 3:28,574,791...30,010,391 		JBrowse link
G RBP1 retinol binding protein 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of RBP1 mRNA CTD PMID:22079614 NCBI chr 3:139,517,438...139,539,742
Ensembl chr 3:139,517,434...139,539,829 		JBrowse link
G REPS2 RALBP1 associated Eps domain containing 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of REPS2 mRNA CTD PMID:22079614 NCBI chr  X:16,946,658...17,196,655
Ensembl chr  X:16,946,658...17,153,272 		JBrowse link
G RFX6 regulatory factor X6 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of RFX6 mRNA CTD PMID:22079614 NCBI chr 6:116,877,242...116,932,161
Ensembl chr 6:116,877,212...116,932,161 		JBrowse link
G RGS16 regulator of G protein signaling 16 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of RGS16 mRNA CTD PMID:22079614 NCBI chr 1:182,598,623...182,604,389
Ensembl chr 1:182,598,623...182,604,389 		JBrowse link
G RHBG Rh family B glycoprotein decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of RHBG mRNA CTD PMID:22079614 NCBI chr 1:156,369,211...156,385,219
Ensembl chr 1:156,369,211...156,385,219 		JBrowse link
G RHOB ras homolog family member B increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of RHOB mRNA CTD PMID:22079614 NCBI chr 2:20,447,074...20,449,440
Ensembl chr 2:20,447,074...20,449,440 		JBrowse link
G RHOBTB1 Rho related BTB domain containing 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of RHOBTB1 mRNA CTD PMID:22079614 NCBI chr10:60,860,860...61,001,967
Ensembl chr10:60,869,438...61,001,440 		JBrowse link
G RHOU ras homolog family member U decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of RHOU mRNA CTD PMID:22079614 NCBI chr 1:228,644,647...228,746,669
Ensembl chr 1:228,735,479...228,746,664 		JBrowse link
G RILP Rab interacting lysosomal protein increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of RILP mRNA CTD PMID:22079614 NCBI chr17:1,646,150...1,649,866
Ensembl chr17:1,646,145...1,649,866 		JBrowse link
G RIN3 Ras and Rab interactor 3 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of RIN3 mRNA CTD PMID:22079614 NCBI chr14:92,513,781...92,688,994
Ensembl chr14:92,513,781...92,688,994 		JBrowse link
G RIPK3 receptor interacting serine/threonine kinase 3 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of RIPK3 mRNA CTD PMID:22079614 NCBI chr14:24,336,025...24,339,991
Ensembl chr14:24,336,025...24,340,022 		JBrowse link
G RIPOR2 RHO family interacting cell polarization regulator 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of RIPOR2 mRNA CTD PMID:20147733 NCBI chr 6:24,804,284...25,042,168
Ensembl chr 6:24,804,282...25,042,170 		JBrowse link
G RNASE8 ribonuclease A family member 8 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of RNASE8 mRNA CTD PMID:22079614 NCBI chr14:21,057,822...21,058,455
Ensembl chr14:21,057,822...21,058,455 		JBrowse link
G RNF144B ring finger protein 144B increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of RNF144B mRNA CTD PMID:22079614 NCBI chr 6:18,387,350...18,468,870
Ensembl chr 6:18,387,350...18,468,870 		JBrowse link
G ROBO2 roundabout guidance receptor 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ROBO2 mRNA CTD PMID:22079614 NCBI chr 3:75,906,675...77,649,964
Ensembl chr 3:75,906,695...77,649,964 		JBrowse link
G ROR1 receptor tyrosine kinase like orphan receptor 1 multiple interactions
decreases expression		 EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ROR1 mRNA
8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ROR1 mRNA		 CTD PMID:16997883 PMID:22079614 NCBI chr 1:63,774,017...64,181,498
Ensembl chr 1:63,774,017...64,181,498 		JBrowse link
G RORA RAR related orphan receptor A decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of RORA mRNA CTD PMID:22079614 NCBI chr15:60,488,284...61,229,302
Ensembl chr15:60,488,284...61,229,302 		JBrowse link
G RORB RAR related orphan receptor B decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of RORB mRNA CTD PMID:22079614 NCBI chr 9:74,497,335...74,693,177
Ensembl chr 9:74,497,335...74,693,177 		JBrowse link
G RPH3AL rabphilin 3A like (without C2 domains) increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of RPH3AL mRNA CTD PMID:22079614 NCBI chr17:212,389...352,807
Ensembl chr17:212,389...386,254 		JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of RRM2 mRNA CTD PMID:22079614 NCBI chr 2:10,122,568...10,211,010
Ensembl chr 2:10,120,698...10,211,725 		JBrowse link
G RSPO1 R-spondin 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of RSPO1 mRNA CTD PMID:22079614 NCBI chr 1:37,611,350...37,634,892
Ensembl chr 1:37,611,350...37,634,892 		JBrowse link
G RUNX1T1 RUNX1 partner transcriptional co-repressor 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of RUNX1T1 mRNA CTD PMID:22079614 NCBI chr 8:91,954,967...92,103,385
Ensembl chr 8:91,954,972...92,103,385 		JBrowse link
G RXRB retinoid X receptor beta decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of RXRB mRNA CTD PMID:22079614 NCBI chr 6:33,193,588...33,200,853
Ensembl chr 6:33,193,588...33,200,665 		JBrowse link
G RXRG retinoid X receptor gamma decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of RXRG mRNA CTD PMID:22079614 NCBI chr 1:165,400,922...165,445,126
Ensembl chr 1:165,400,922...165,445,355 		JBrowse link
G RYR3 ryanodine receptor 3 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of RYR3 mRNA CTD PMID:22079614 NCBI chr15:33,310,967...33,866,102
Ensembl chr15:33,310,962...33,866,121 		JBrowse link
G SAMD3 sterile alpha motif domain containing 3 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of SAMD3 mRNA CTD PMID:22079614 NCBI chr 6:130,142,752...130,365,868
Ensembl chr 6:130,144,315...130,365,425 		JBrowse link
G SC5D sterol-C5-desaturase increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SC5D mRNA CTD PMID:22079614 NCBI chr11:121,292,771...121,313,410
Ensembl chr11:121,292,681...121,313,410 		JBrowse link
G SCARB1 scavenger receptor class B member 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SCARB1 mRNA CTD PMID:22079614 NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668 		JBrowse link
G SCG2 secretogranin II increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SCG2 mRNA CTD PMID:22079614 NCBI chr 2:223,596,940...223,602,361
Ensembl chr 2:223,596,940...223,602,361 		JBrowse link
G SCGB1C1 secretoglobin family 1C member 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SCGB1C1 mRNA CTD PMID:22079614 NCBI chr11:188,050...194,575
Ensembl chr11:193,078...194,575 		JBrowse link
G SCRG1 stimulator of chondrogenesis 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SCRG1 mRNA CTD PMID:22079614 NCBI chr 4:173,384,701...173,519,144
Ensembl chr 4:173,384,701...173,406,380 		JBrowse link
G SERPINA11 serpin family A member 11 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SERPINA11 mRNA CTD PMID:22079614 NCBI chr14:94,442,464...94,452,800
Ensembl chr14:94,442,464...94,452,800 		JBrowse link
G SERPINE1 serpin family E member 1 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of SERPINE1 mRNA CTD PMID:16997883 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SERPINI1 serpin family I member 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SERPINI1 mRNA CTD PMID:22079614 NCBI chr 3:167,735,721...167,825,569
Ensembl chr 3:167,735,243...167,825,569 		JBrowse link
G SESN3 sestrin 3 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SESN3 mRNA CTD PMID:20147733 NCBI chr11:95,165,513...95,232,475
Ensembl chr11:95,165,513...95,232,541 		JBrowse link
G SF1 splicing factor 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SF1 mRNA CTD PMID:22079614 NCBI chr11:64,764,606...64,778,542
Ensembl chr11:64,764,606...64,778,786 		JBrowse link
G SFRP1 secreted frizzled related protein 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SFRP1 mRNA CTD PMID:20147733 PMID:22079614 NCBI chr 8:41,261,962...41,309,473
Ensembl chr 8:41,261,962...41,309,473 		JBrowse link
G SFTPA2 surfactant protein A2 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of SFTPA2 mRNA CTD PMID:16997883 NCBI chr10:79,555,852...79,560,407
Ensembl chr10:79,555,852...79,560,407 		JBrowse link
G SFTPB surfactant protein B multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of SFTPB mRNA CTD PMID:16997883 NCBI chr 2:85,657,307...85,668,741
Ensembl chr 2:85,657,314...85,668,741 		JBrowse link
G SFTPC surfactant protein C multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of SFTPC mRNA CTD PMID:16997883 NCBI chr 8:22,157,383...22,164,479
Ensembl chr 8:22,156,913...22,164,479 		JBrowse link
G SGCD sarcoglycan delta increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SGCD mRNA CTD PMID:20147733 NCBI chr 5:155,727,832...156,767,788
Ensembl chr 5:155,870,344...156,767,788 		JBrowse link
G SGK1 serum/glucocorticoid regulated kinase 1 increases expression
multiple interactions		 EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SGK1 mRNA
Estradiol inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SGK1 mRNA]; Genistein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SGK1 mRNA]		 CTD PMID:21056929 NCBI chr 6:134,169,256...134,318,112
Ensembl chr 6:134,169,248...134,318,112 		JBrowse link
G SGMS1 sphingomyelin synthase 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SGMS1 mRNA CTD PMID:22079614 NCBI chr10:50,305,600...50,625,184
Ensembl chr10:50,305,586...50,625,163 		JBrowse link
G SH3BP5 SH3 domain binding protein 5 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SH3BP5 mRNA CTD PMID:22079614 NCBI chr 3:15,254,353...15,341,380
Ensembl chr 3:15,254,353...15,341,368 		JBrowse link
G SIRT1 sirtuin 1 multiple interactions EXP [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of SIRT1 protein CTD PMID:16709600 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G SIRT3 sirtuin 3 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SIRT3 mRNA CTD PMID:23166782 NCBI chr11:215,030...236,931
Ensembl chr11:215,030...236,931 		JBrowse link
G SLC16A6 solute carrier family 16 member 6 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SLC16A6 mRNA CTD PMID:20147733 NCBI chr17:68,267,026...68,291,479
Ensembl chr17:68,267,026...68,291,267 		JBrowse link
G SLC17A5 solute carrier family 17 member 5 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of SLC17A5 mRNA CTD PMID:22079614 NCBI chr 6:73,593,379...73,653,992
Ensembl chr 6:73,593,379...73,653,992 		JBrowse link
G SLC22A11 solute carrier family 22 member 11 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SLC22A11 mRNA CTD PMID:22079614 NCBI chr11:64,555,941...64,572,875
Ensembl chr11:64,555,690...64,572,875 		JBrowse link
G SLC25A36 solute carrier family 25 member 36 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of SLC25A36 mRNA CTD PMID:16997883 NCBI chr 3:140,941,836...140,980,995
Ensembl chr 3:140,941,830...140,980,995 		JBrowse link
G SLC26A4 solute carrier family 26 member 4 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SLC26A4 protein CTD PMID:22811483 NCBI chr 7:107,660,828...107,717,809
Ensembl chr 7:107,660,828...107,717,809 		JBrowse link
G SLC26A7 solute carrier family 26 member 7 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SLC26A7 mRNA CTD PMID:22079614 NCBI chr 8:91,209,496...91,398,155
Ensembl chr 8:91,209,494...91,398,155 		JBrowse link
G SLC27A2 solute carrier family 27 member 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SLC27A2 mRNA CTD PMID:22079614 NCBI chr15:50,182,196...50,236,385
Ensembl chr15:50,182,196...50,236,385 		JBrowse link
G SLC27A4 solute carrier family 27 member 4 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of SLC27A4 mRNA CTD PMID:22079614 NCBI chr 9:128,340,527...128,361,470
Ensembl chr 9:128,340,527...128,361,470 		JBrowse link
G SLC2A12 solute carrier family 2 member 12 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SLC2A12 mRNA CTD PMID:20147733 NCBI chr 6:133,987,581...134,052,624
Ensembl chr 6:133,987,581...134,052,624 		JBrowse link
G SLC39A8 solute carrier family 39 member 8 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of SLC39A8 mRNA CTD PMID:16997883 NCBI chr 4:102,251,041...102,345,482
Ensembl chr 4:102,251,080...102,431,258 		JBrowse link
G SLC3A2 solute carrier family 3 member 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of SLC3A2 mRNA CTD PMID:22079614 NCBI chr11:62,856,109...62,888,860
Ensembl chr11:62,856,004...62,888,880 		JBrowse link
G SLC51A solute carrier family 51 member A increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SLC51A mRNA CTD PMID:22079614 NCBI chr 3:196,216,534...196,233,427
Ensembl chr 3:196,211,487...196,243,178 		JBrowse link
G SLC5A12 solute carrier family 5 member 12 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SLC5A12 mRNA CTD PMID:22079614 NCBI chr11:26,667,020...26,723,389
Ensembl chr11:26,667,020...26,723,427 		JBrowse link
G SLC5A7 solute carrier family 5 member 7 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SLC5A7 mRNA CTD PMID:22079614 NCBI chr 2:107,986,524...108,013,994
Ensembl chr 2:107,986,523...108,013,994 		JBrowse link
G SLC6A14 solute carrier family 6 member 14 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of SLC6A14 mRNA CTD PMID:16997883 NCBI chr  X:116,436,606...116,461,458
Ensembl chr  X:116,436,606...116,461,458 		JBrowse link
G SLC6A9 solute carrier family 6 member 9 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SLC6A9 mRNA CTD PMID:20147733 NCBI chr 1:43,996,483...44,031,462
Ensembl chr 1:43,991,500...44,031,467 		JBrowse link
G SLC7A1 solute carrier family 7 member 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SLC7A1 mRNA CTD PMID:22079614 NCBI chr13:29,509,414...29,595,688
Ensembl chr13:29,509,414...29,595,688 		JBrowse link
G SLC7A11 solute carrier family 7 member 11 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of SLC7A11 mRNA CTD PMID:22079614 NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349 		JBrowse link
G SLC9A1 solute carrier family 9 member A1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SLC9A1 mRNA CTD PMID:22079614 NCBI chr 1:27,098,809...27,155,125
Ensembl chr 1:27,098,809...27,166,981 		JBrowse link
G SLCO4C1 solute carrier organic anion transporter family member 4C1 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of SLCO4C1 mRNA CTD PMID:16997883 NCBI chr 5:102,233,986...102,296,284
Ensembl chr 5:102,233,986...102,296,284 		JBrowse link
G SMOC1 SPARC related modular calcium binding 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SMOC1 mRNA CTD PMID:20147733 NCBI chr14:69,879,416...70,032,366
Ensembl chr14:69,854,131...70,032,366 		JBrowse link
G SMOX spermine oxidase increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SMOX mRNA CTD PMID:20147733 NCBI chr20:4,148,828...4,187,727
Ensembl chr20:4,120,980...4,187,747 		JBrowse link
G SNCA synuclein alpha increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SNCA mRNA CTD PMID:22079614 NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315 		JBrowse link
G SOAT1 sterol O-acyltransferase 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SOAT1 mRNA CTD PMID:22079614 NCBI chr 1:179,293,797...179,358,680
Ensembl chr 1:179,293,714...179,358,680 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SOCS3 mRNA CTD PMID:22079614 NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077 		JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions
increases expression		 EXP [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of SOD1 mRNA
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SOD1 mRNA		 CTD PMID:16709600 PMID:22079614 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions EXP [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of SOD2 mRNA; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of SOD2 protein; FOXO1 protein affects the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of SOD2 mRNA] CTD PMID:16709600 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SOX5 SRY-box transcription factor 5 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SOX5 mRNA CTD PMID:22079614 NCBI chr12:23,529,504...24,562,650
Ensembl chr12:23,529,504...24,562,544 		JBrowse link
G SPATA9 spermatogenesis associated 9 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SPATA9 mRNA CTD PMID:22079614 NCBI chr 5:95,652,181...95,732,102
Ensembl chr 5:95,652,181...95,698,711 		JBrowse link
G SPINK5 serine peptidase inhibitor Kazal type 5 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SPINK5 mRNA CTD PMID:22079614 NCBI chr 5:148,063,980...148,137,382
Ensembl chr 5:148,025,683...148,137,382 		JBrowse link
G SPOCK2 SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SPOCK2 mRNA CTD PMID:22079614 NCBI chr10:72,059,034...72,089,032
Ensembl chr10:72,059,034...72,089,032 		JBrowse link
G SPON1 spondin 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SPON1 mRNA CTD PMID:20147733 NCBI chr11:13,962,723...14,268,133
Ensembl chr11:13,962,723...14,268,133 		JBrowse link
G SPP1 secreted phosphoprotein 1 multiple interactions
decreases expression		 ISO
EXP		 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Glucose results in increased secretion of SPP1 protein]; Dinitrochlorobenzene inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Glucose results in increased secretion of SPP1 protein]]; KT 5823 inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Glucose results in increased secretion of SPP1 protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Glucose results in increased secretion of SPP1 protein]]
8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of SPP1 mRNA		 CTD PMID:20453393 PMID:22079614 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532 		JBrowse link
G SPRR1A small proline rich protein 1A increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SPRR1A mRNA CTD PMID:22079614 NCBI chr 1:152,984,081...152,985,814
Ensembl chr 1:152,984,081...152,985,814 		JBrowse link
G SPRR1B small proline rich protein 1B increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SPRR1B mRNA CTD PMID:22079614 NCBI chr 1:153,031,203...153,032,900
Ensembl chr 1:153,031,203...153,032,900 		JBrowse link
G SPRR3 small proline rich protein 3 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SPRR3 mRNA CTD PMID:22079614 NCBI chr 1:153,001,749...153,003,856
Ensembl chr 1:153,001,747...153,003,856 		JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SPRY2 mRNA CTD PMID:22079614 NCBI chr13:80,335,976...80,341,126
Ensembl chr13:80,335,976...80,341,126 		JBrowse link
G SQLE squalene epoxidase increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SQLE mRNA CTD PMID:22079614 NCBI chr 8:124,998,505...125,022,283
Ensembl chr 8:124,998,497...125,022,283 		JBrowse link
G SRD5A1 steroid 5 alpha-reductase 1 increases expression ISO 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SRD5A1 mRNA CTD PMID:24014645 NCBI chr 5:6,633,440...6,674,386
Ensembl chr 5:6,633,290...6,676,539 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of SREBF1 mRNA CTD PMID:22079614 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002 		JBrowse link
G ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ST3GAL1 mRNA CTD PMID:22079614 NCBI chr 8:133,454,848...133,571,887
Ensembl chr 8:133,454,848...133,571,926 		JBrowse link
G ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ST3GAL6 mRNA CTD PMID:22079614 NCBI chr 3:98,732,262...98,795,852
Ensembl chr 3:98,732,236...98,821,201 		JBrowse link
G STAR steroidogenic acute regulatory protein increases expression
multiple interactions		 ISO
EXP		 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA; 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [LEP protein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR protein]]; bifenthrin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA]; bifenthrin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR protein]; LEP protein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR protein]; LEPR protein affects the reaction [LEP protein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR protein]]; Mitotane inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA]; SB 203580 inhibits the reaction [LEP protein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR protein]]; T-2 Toxin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA]
2,2',4,4'-tetrahydroxybenzophenone promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA]; 8-Bromo Cyclic Adenosine Monophosphate promotes the reaction [sodium arsenite results in increased expression of STAR mRNA]; 8-Bromo Cyclic Adenosine Monophosphate promotes the reaction [sodium arsenite results in increased expression of STAR protein]; Anisomycin promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA]; Dantrolene inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA]; Hydrocarbons, Chlorinated inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR protein]; Ryanodine inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA]; SB 203580 promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA]; SB 203580 promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR protein]; sodium arsenite promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA]; sodium arsenite promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR protein]; THRA mutant form inhibits the reaction [2,2',4,4'-tetrahydroxybenzophenone promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA]]; Triiodothyronine inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA]; Valproic Acid inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA]; Valproic Acid inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR protein]		 CTD PMID:15713539 PMID:16254025 PMID:18815356 PMID:19849856 PMID:20732403 More... NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992 		JBrowse link
G STARD3 StAR related lipid transfer domain containing 3 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of STARD3 mRNA CTD PMID:22079614 NCBI chr17:39,637,144...39,664,201
Ensembl chr17:39,637,090...39,664,201 		JBrowse link
G STC1 stanniocalcin 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STC1 mRNA CTD PMID:20147733 NCBI chr 8:23,841,929...23,854,806
Ensembl chr 8:23,841,929...23,854,806 		JBrowse link
G STC2 stanniocalcin 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of STC2 mRNA CTD PMID:22079614 NCBI chr 5:173,314,723...173,328,414
Ensembl chr 5:173,314,723...173,328,447 		JBrowse link
G STK17B serine/threonine kinase 17b decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of STK17B mRNA CTD PMID:22079614 NCBI chr 2:196,133,583...196,176,483
Ensembl chr 2:196,133,583...196,176,503 		JBrowse link
G STRA6 signaling receptor and transporter of retinol STRA6 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of STRA6 mRNA CTD PMID:22079614 NCBI chr15:74,179,466...74,212,259
Ensembl chr15:74,179,466...74,212,267 		JBrowse link
G STX2 syntaxin 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STX2 mRNA CTD PMID:22079614 NCBI chr12:130,789,600...130,839,250
Ensembl chr12:130,789,600...130,839,254 		JBrowse link
G STX3 syntaxin 3 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of STX3 mRNA CTD PMID:22079614 NCBI chr11:59,754,188...59,805,878
Ensembl chr11:59,713,456...59,805,882 		JBrowse link
G SULT2A1 sulfotransferase family 2A member 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of SULT2A1 mRNA CTD PMID:22079614 NCBI chr19:47,870,467...47,886,315
Ensembl chr19:47,870,467...47,886,315 		JBrowse link
G SULT4A1 sulfotransferase family 4A member 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SULT4A1 mRNA CTD PMID:22079614 NCBI chr22:43,824,509...43,862,513
Ensembl chr22:43,824,509...43,862,513 		JBrowse link
G SV2C synaptic vesicle glycoprotein 2C increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SV2C mRNA CTD PMID:22079614 NCBI chr 5:75,847,464...76,353,939
Ensembl chr 5:76,083,383...76,353,939 		JBrowse link
G SVIL supervillin increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SVIL mRNA CTD PMID:20147733 NCBI chr10:29,457,338...29,736,936
Ensembl chr10:29,457,338...29,736,959 		JBrowse link
G SYNE1 spectrin repeat containing nuclear envelope protein 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of SYNE1 mRNA CTD PMID:22079614 NCBI chr 6:152,121,687...152,637,362
Ensembl chr 6:152,121,687...152,637,801 		JBrowse link
G SYT12 synaptotagmin 12 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SYT12 mRNA CTD PMID:22079614 NCBI chr11:67,006,771...67,050,863
Ensembl chr11:67,006,778...67,050,863 		JBrowse link
G SYT9 synaptotagmin 9 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SYT9 mRNA CTD PMID:22079614 NCBI chr11:7,238,778...7,469,043
Ensembl chr11:7,238,778...7,469,043 		JBrowse link
G TAC1 tachykinin precursor 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TAC1 mRNA CTD PMID:22079614 NCBI chr 7:97,732,086...97,740,472
Ensembl chr 7:97,732,084...97,740,472 		JBrowse link
G TACC2 transforming acidic coiled-coil containing protein 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TACC2 mRNA CTD PMID:22079614 NCBI chr10:121,989,163...122,254,542
Ensembl chr10:121,989,163...122,254,545 		JBrowse link
G TAFA5 TAFA chemokine like family member 5 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TAFA5 mRNA CTD PMID:22079614 NCBI chr22:48,489,553...48,751,932
Ensembl chr22:48,489,553...48,850,912 		JBrowse link
G TBC1D2 TBC1 domain family member 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of TBC1D2 mRNA CTD PMID:20147733 NCBI chr 9:98,198,998...98,255,649
Ensembl chr 9:98,199,011...98,255,649 		JBrowse link
G TCF21 transcription factor 21 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TCF21 mRNA CTD PMID:20147733 NCBI chr 6:133,889,113...133,895,537
Ensembl chr 6:133,889,113...133,895,553 		JBrowse link
G TEF TEF transcription factor, PAR bZIP family member decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of TEF mRNA CTD PMID:22079614 NCBI chr22:41,367,455...41,399,326
Ensembl chr22:41,367,333...41,399,326 		JBrowse link
G TENT5A terminal nucleotidyltransferase 5A increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TENT5A mRNA CTD PMID:22079614 NCBI chr 6:81,745,730...81,752,681
Ensembl chr 6:81,491,439...81,752,774 		JBrowse link
G TESK1 testis associated actin remodelling kinase 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TESK1 mRNA CTD PMID:22079614 NCBI chr 9:35,605,262...35,610,033
Ensembl chr 9:35,605,262...35,610,041 		JBrowse link
G TFPI2 tissue factor pathway inhibitor 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TFPI2 mRNA CTD PMID:20147733 PMID:22079614 NCBI chr 7:93,885,396...93,890,753
Ensembl chr 7:93,885,396...93,890,753 		JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of TGFB1 mRNA CTD PMID:16997883 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TGFB1I1 transforming growth factor beta 1 induced transcript 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of TGFB1I1 mRNA CTD PMID:22079614 NCBI chr16:31,472,152...31,477,960
Ensembl chr16:31,471,585...31,477,960 		JBrowse link
G TGFB2 transforming growth factor beta 2 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of TGFB2 mRNA CTD PMID:16997883 NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619 		JBrowse link
G TGFB3 transforming growth factor beta 3 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of TGFB3 mRNA CTD PMID:16997883 NCBI chr14:75,958,097...75,983,011
Ensembl chr14:75,958,097...75,983,011 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of TGFBR2 mRNA CTD PMID:22079614 NCBI chr 3:30,606,356...30,694,142
Ensembl chr 3:30,606,601...30,694,142 		JBrowse link
G THRA thyroid hormone receptor alpha multiple interactions ISO THRA mutant form inhibits the reaction [2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 mRNA]]; THRA mutant form inhibits the reaction [2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 mRNA]]; THRA mutant form inhibits the reaction [2,2',4,4'-tetrahydroxybenzophenone promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HSD3B1 mRNA]]; THRA mutant form inhibits the reaction [2,2',4,4'-tetrahydroxybenzophenone promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA]] CTD PMID:21726595 NCBI chr17:40,062,193...40,093,867
Ensembl chr17:40,058,290...40,093,867 		JBrowse link
G TIPARP TCDD inducible poly(ADP-ribose) polymerase increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TIPARP mRNA CTD PMID:22079614 NCBI chr 3:156,674,590...156,706,770
Ensembl chr 3:156,673,235...156,706,770 		JBrowse link
G TLCD3A TLC domain containing 3A increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TLCD3A mRNA CTD PMID:22079614 NCBI chr17:732,596...742,968
Ensembl chr17:732,412...742,968 		JBrowse link
G TMC5 transmembrane channel like 5 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of TMC5 mRNA CTD PMID:16997883 NCBI chr16:19,410,539...19,499,113
Ensembl chr16:19,410,496...19,499,113 		JBrowse link
G TMOD1 tropomodulin 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TMOD1 mRNA CTD PMID:20147733 NCBI chr 9:97,501,180...97,601,743
Ensembl chr 9:97,501,180...97,601,743 		JBrowse link
G TMX4 thioredoxin related transmembrane protein 4 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TMX4 mRNA CTD PMID:20147733 NCBI chr20:7,977,346...8,019,761
Ensembl chr20:7,977,346...8,019,805 		JBrowse link
G TNC tenascin C multiple interactions
increases expression		 EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of TNC mRNA
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TNC mRNA		 CTD PMID:16997883 PMID:20147733 NCBI chr 9:115,019,575...115,118,157
Ensembl chr 9:115,019,575...115,118,207 		JBrowse link
G TNF tumor necrosis factor multiple interactions EXP
ISO		 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [TNF protein results in increased secretion of CCL2 protein]]
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]		 CTD PMID:10495789 PMID:11230753 PMID:21803157 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 multiple interactions
increases expression		 EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of TNFAIP3 mRNA
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TNFAIP3 mRNA		 CTD PMID:16997883 PMID:22079614 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TNFRSF10A mRNA CTD PMID:22079614 NCBI chr 8:23,190,452...23,225,102
Ensembl chr 8:23,190,452...23,225,102 		JBrowse link
G TNFRSF12A TNF receptor superfamily member 12A increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TNFRSF12A mRNA CTD PMID:22079614 NCBI chr16:3,020,368...3,022,383
Ensembl chr16:3,018,445...3,022,383 		JBrowse link
G TNFRSF19 TNF receptor superfamily member 19 decreases expression
increases expression		 EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of TNFRSF19 mRNA
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TNFRSF19 mRNA		 CTD PMID:20147733 PMID:22079614 NCBI chr13:23,570,412...23,676,093
Ensembl chr13:23,570,370...23,676,104 		JBrowse link
G TNFSF4 TNF superfamily member 4 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of TNFSF4 mRNA CTD PMID:16997883 NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,183,731...173,207,331 		JBrowse link
G TNNT2 troponin T2, cardiac type increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TNNT2 mRNA CTD PMID:22079614 NCBI chr 1:201,359,014...201,377,680
Ensembl chr 1:201,359,008...201,377,764 		JBrowse link
G TP53 tumor protein p53 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TP53; 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TP53 protein CTD PMID:10642304 PMID:11802967 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538 		JBrowse link
G TPH2 tryptophan hydroxylase 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TPH2 mRNA CTD PMID:22079614 NCBI chr12:71,938,845...72,032,440
Ensembl chr12:71,938,845...72,186,618 		JBrowse link
G TPM1 tropomyosin 1 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of TPM1 mRNA CTD PMID:16997883 NCBI chr15:63,042,747...63,071,915
Ensembl chr15:63,042,620...63,071,915 		JBrowse link
G TPMT thiopurine S-methyltransferase increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TPMT mRNA CTD PMID:22079614 NCBI chr 6:18,128,311...18,155,169
Ensembl chr 6:18,128,311...18,155,077 		JBrowse link
G TRBV21-1 T cell receptor beta variable 21-1 (pseudogene) multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of TRBV21-1 mRNA CTD PMID:16997883 NCBI chr 7:142,636,924...142,637,384
Ensembl chr 7:142,636,924...142,637,384 		JBrowse link
G TRIB3 tribbles pseudokinase 3 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TRIB3 mRNA CTD PMID:22079614 NCBI chr20:380,760...397,559
Ensembl chr20:362,835...397,559 		JBrowse link
G TRIM2 tripartite motif containing 2 multiple interactions
increases expression		 EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of TRIM2 mRNA
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TRIM2 mRNA		 CTD PMID:16997883 PMID:20147733 NCBI chr 4:153,152,163...153,339,317
Ensembl chr 4:153,152,163...153,339,319 		JBrowse link
G TRIM24 tripartite motif containing 24 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TRIM24 mRNA CTD PMID:22079614 NCBI chr 7:138,460,259...138,589,996
Ensembl chr 7:138,460,259...138,589,996 		JBrowse link
G TRIP10 thyroid hormone receptor interactor 10 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of TRIP10 mRNA CTD PMID:22079614 NCBI chr19:6,739,680...6,751,530
Ensembl chr19:6,737,925...6,751,530 		JBrowse link
G TRPA1 transient receptor potential cation channel subfamily A member 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TRPA1 mRNA CTD PMID:22079614 NCBI chr 8:72,021,250...72,090,010
Ensembl chr 8:72,019,917...72,075,584 		JBrowse link
G TSHZ2 teashirt zinc finger homeobox 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TSHZ2 mRNA CTD PMID:20147733 NCBI chr20:52,972,358...53,495,330
Ensembl chr20:52,972,358...53,495,330 		JBrowse link
G TTC9 tetratricopeptide repeat domain 9 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TTC9 mRNA CTD PMID:22079614 NCBI chr14:70,641,916...70,675,366
Ensembl chr14:70,641,916...70,675,366 		JBrowse link
G TXLNGY taxilin gamma Y-linked (pseudogene) increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TXLNGY mRNA CTD PMID:22079614 NCBI chr  Y:19,567,358...19,607,170
Ensembl chr  Y:19,567,382...19,604,120
Ensembl chr  Y:19,567,382...19,604,120 		JBrowse link
G TXN thioredoxin multiple interactions ISO 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Glucose results in decreased expression of TXN1 protein] CTD PMID:20453393 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507 		JBrowse link
G UGT2B11 UDP glucuronosyltransferase family 2 member B11 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of UGT2B11 mRNA CTD PMID:22079614 NCBI chr 4:69,199,951...69,224,984
Ensembl chr 4:69,199,951...69,214,748 		JBrowse link
G UGT2B17 UDP glucuronosyltransferase family 2 member B17 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of UGT2B17 mRNA CTD PMID:22079614 NCBI chr 4:68,537,173...68,576,322
Ensembl chr 4:68,537,173...68,576,413 		JBrowse link
G UGT2B7 UDP glucuronosyltransferase family 2 member B7 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of UGT2B7 mRNA CTD PMID:22079614 NCBI chr 4:69,051,375...69,112,987
Ensembl chr 4:69,051,363...69,112,987 		JBrowse link
G UNC5B unc-5 netrin receptor B decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of UNC5B mRNA CTD PMID:22079614 NCBI chr10:71,212,570...71,302,864
Ensembl chr10:71,212,570...71,302,864 		JBrowse link
G USHBP1 USH1 protein network component harmonin binding protein 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of USHBP1 mRNA CTD PMID:22079614 NCBI chr19:17,249,171...17,264,745
Ensembl chr19:17,249,171...17,282,786 		JBrowse link
G UTS2 urotensin 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of UTS2 mRNA CTD PMID:22079614 NCBI chr 1:7,847,612...7,913,249
Ensembl chr 1:7,843,083...7,853,512 		JBrowse link
G UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of UTY mRNA CTD PMID:22079614 NCBI chr  Y:13,233,895...13,480,670
Ensembl chr  Y:13,234,577...13,480,673 		JBrowse link
G VDR vitamin D receptor increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of VDR mRNA CTD PMID:22079614 NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048 		JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions
increases expression		 EXP
ISO		 [PTGS2 co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of VEGFA
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of VEGFA mRNA		 CTD PMID:10788502 PMID:12821125 PMID:20147733 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G VEGFC vascular endothelial growth factor C increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of VEGFC mRNA CTD PMID:22079614 NCBI chr 4:176,683,538...176,792,922
Ensembl chr 4:176,683,538...176,792,922 		JBrowse link
G VGF VGF nerve growth factor inducible increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of VGF mRNA CTD PMID:22079614 NCBI chr 7:101,162,509...101,169,952
Ensembl chr 7:101,162,509...101,165,569 		JBrowse link
G VGLL3 vestigial like family member 3 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of VGLL3 mRNA CTD PMID:20147733 NCBI chr 3:86,937,973...86,991,149
Ensembl chr 3:86,876,388...86,991,149 		JBrowse link
G VIPR1 vasoactive intestinal peptide receptor 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of VIPR1 mRNA CTD PMID:22079614 NCBI chr 3:42,489,299...42,537,568
Ensembl chr 3:42,489,299...42,537,573 		JBrowse link
G VLDLR very low density lipoprotein receptor decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of VLDLR mRNA CTD PMID:22079614 NCBI chr 9:2,621,787...2,660,056
Ensembl chr 9:2,621,182...2,660,056 		JBrowse link
G VMO1 vitelline membrane outer layer 1 homolog increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of VMO1 mRNA CTD PMID:20147733 NCBI chr17:4,785,285...4,786,364
Ensembl chr17:4,785,285...4,786,433 		JBrowse link
G WDR17 WD repeat domain 17 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of WDR17 mRNA CTD PMID:22079614 NCBI chr 4:176,065,841...176,182,815
Ensembl chr 4:176,065,841...176,182,818 		JBrowse link
G WHRN whirlin increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of WHRN mRNA CTD PMID:22079614 NCBI chr 9:114,402,080...114,505,473
Ensembl chr 9:114,402,080...114,505,473 		JBrowse link
G WIF1 WNT inhibitory factor 1 multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of WIF1 mRNA CTD PMID:16997883 NCBI chr12:65,050,626...65,121,305
Ensembl chr12:65,050,626...65,121,305 		JBrowse link
G WNT4 Wnt family member 4 decreases expression
multiple interactions		 EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of WNT4 mRNA
[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of WNT4 mRNA; NR3C1 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of WNT4 mRNA]		 CTD PMID:22079614 PMID:23275455 NCBI chr 1:22,117,313...22,143,097
Ensembl chr 1:22,117,313...22,143,969 		JBrowse link
G WNT5B Wnt family member 5B multiple interactions EXP [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of WNT5B mRNA CTD PMID:16997883 NCBI chr12:1,617,056...1,647,212
Ensembl chr12:1,529,891...1,647,212 		JBrowse link
G XBP1 X-box binding protein 1 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of XBP1 mRNA CTD PMID:22079614 NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597 		JBrowse link
G ZBTB12 zinc finger and BTB domain containing 12 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ZBTB12 mRNA CTD PMID:22079614 NCBI chr 6:31,899,613...31,902,086
Ensembl chr 6:31,899,613...31,902,086 		JBrowse link
G ZBTB18 zinc finger and BTB domain containing 18 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ZBTB18 mRNA CTD PMID:22079614 NCBI chr 1:244,048,491...244,057,476
Ensembl chr 1:244,048,547...244,057,476 		JBrowse link
G ZBTB32 zinc finger and BTB domain containing 32 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ZBTB32 mRNA CTD PMID:22079614 NCBI chr19:35,704,558...35,717,038
Ensembl chr19:35,704,558...35,717,038 		JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ZFP36L1 mRNA CTD PMID:22079614 NCBI chr14:68,787,655...68,796,243
Ensembl chr14:68,787,660...68,796,253 		JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ZFP36L2 mRNA CTD PMID:22079614 NCBI chr 2:43,222,402...43,226,606
Ensembl chr 2:43,222,402...43,226,606 		JBrowse link
G ZNF436 zinc finger protein 436 decreases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ZNF436 mRNA CTD PMID:22079614 NCBI chr 1:23,359,448...23,369,836
Ensembl chr 1:23,359,448...23,369,836 		JBrowse link
G ZNF454 zinc finger protein 454 increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ZNF454 mRNA CTD PMID:22079614 NCBI chr 5:178,941,198...178,990,028
Ensembl chr 5:178,941,191...178,966,433 		JBrowse link
G ZNF486 zinc finger protein 486 multiple interactions EXP [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of ZNF486 mRNA; NR3C1 protein inhibits the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of ZNF486 mRNA] CTD PMID:23275455 NCBI chr19:20,167,214...20,200,488
Ensembl chr19:20,167,214...20,200,488 		JBrowse link
G ZNF847P zinc finger protein 847, pseudogene increases expression EXP 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ZNF847P mRNA CTD PMID:22079614 NCBI chr 1:227,697,032...227,697,707
Ensembl chr 1:227,696,892...227,706,699 		JBrowse link
8-bromo-3',5'-cyclic GMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARHGEF17 Rho guanine nucleotide exchange factor 17 multiple interactions EXP [8-bromocyclic GMP co-treated with PRKG1 protein co-treated with ARHGEF17 protein] results in increased activity of SRF protein CTD PMID:23195829 NCBI chr11:73,308,276...73,369,388
Ensembl chr11:73,308,276...73,369,388 		JBrowse link
G CASP3 caspase 3 multiple interactions ISO 8-bromocyclic GMP inhibits the reaction [TNF protein results in increased activity of CASP3 protein]; KT 5823 inhibits the reaction [8-bromocyclic GMP inhibits the reaction [TNF protein results in increased activity of CASP3 protein]] CTD PMID:9388267 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G COX4I1 cytochrome c oxidase subunit 4I1 increases expression
multiple interactions		 EXP 8-bromocyclic GMP results in increased expression of COX4I1 protein
tin protoporphyrin IX inhibits the reaction [8-bromocyclic GMP results in increased expression of COX4I1 protein]		 CTD PMID:24041027 NCBI chr16:85,799,695...85,807,068
Ensembl chr16:85,798,633...85,807,068 		JBrowse link
G DUSP10 dual specificity phosphatase 10 increases expression EXP 8-bromocyclic GMP results in increased expression of DUSP10 mRNA; 8-bromocyclic GMP results in increased expression of DUSP10 protein CTD PMID:29165873 NCBI chr 1:221,701,424...221,742,089
Ensembl chr 1:221,701,424...221,742,089 		JBrowse link
G EDN1 endothelin 1 multiple interactions ISO
EXP		 8-bromocyclic GMP inhibits the reaction [[EDN1 protein binds to and results in increased activity of EDNRB protein] which results in decreased activity of TH protein]
8-bromocyclic GMP inhibits the reaction [cobaltous chloride results in increased expression of EDN1 mRNA]; 8-bromocyclic GMP inhibits the reaction [cobaltous chloride results in increased expression of EDN1 protein]		 CTD PMID:16023617 PMID:29165873 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G EDN3 endothelin 3 multiple interactions ISO 8-bromocyclic GMP inhibits the reaction [[EDN3 protein binds to and results in increased activity of EDNRB protein] which results in decreased activity of TH protein] CTD PMID:16023617 NCBI chr20:59,300,611...59,325,992
Ensembl chr20:59,300,443...59,325,992 		JBrowse link
G EDNRB endothelin receptor type B multiple interactions ISO 8-bromocyclic GMP inhibits the reaction [[EDN1 protein binds to and results in increased activity of EDNRB protein] which results in decreased activity of TH protein]; 8-bromocyclic GMP inhibits the reaction [[EDN3 protein binds to and results in increased activity of EDNRB protein] which results in decreased activity of TH protein] CTD PMID:16023617 NCBI chr13:77,895,481...77,975,527
Ensembl chr13:77,895,481...77,975,529 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions EXP 8-bromocyclic GMP inhibits the reaction [cobaltous chloride results in increased expression of HIF1A mRNA]; 8-bromocyclic GMP inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein] CTD PMID:29165873 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HMOX1 heme oxygenase 1 increases expression EXP 8-bromocyclic GMP results in increased expression of HMOX1 mRNA; 8-bromocyclic GMP results in increased expression of HMOX1 protein CTD PMID:24041027 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G IL1B interleukin 1 beta multiple interactions EXP 8-bromocyclic GMP promotes the reaction [IL1B protein results in increased abundance of Nitrites]; Dipyridamole promotes the reaction [8-bromocyclic GMP promotes the reaction [IL1B protein results in increased abundance of Nitrites]] CTD PMID:8904084 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL4 interleukin 4 increases expression
multiple interactions		 ISO 8-bromocyclic GMP results in increased expression of IL4 mRNA
Cyclosporine inhibits the reaction [8-bromocyclic GMP results in increased expression of IL4 mRNA]		 CTD PMID:16533816 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 decreases phosphorylation EXP 8-bromocyclic GMP results in decreased phosphorylation of MAPK1 protein CTD PMID:17828804 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 decreases phosphorylation EXP 8-bromocyclic GMP results in decreased phosphorylation of MAPK3 protein CTD PMID:17828804 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor decreases phosphorylation EXP 8-bromocyclic GMP results in decreased phosphorylation of MYC protein CTD PMID:17828804 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G NDUFB8 NADH:ubiquinone oxidoreductase subunit B8 increases expression
multiple interactions		 EXP 8-bromocyclic GMP results in increased expression of NDUFB8 protein
tin protoporphyrin IX inhibits the reaction [8-bromocyclic GMP results in increased expression of NDUFB8 protein]		 CTD PMID:24041027 NCBI chr10:100,523,729...100,529,923
Ensembl chr10:100,523,740...100,530,000 		JBrowse link
G NFATC1 nuclear factor of activated T cells 1 affects localization ISO 8-bromocyclic GMP affects the localization of NFATC1 protein CTD PMID:16533816 NCBI chr18:79,395,930...79,529,323
Ensembl chr18:79,395,856...79,529,325 		JBrowse link
G NRF1 nuclear respiratory factor 1 increases expression
multiple interactions		 EXP 8-bromocyclic GMP results in increased expression of NRF1 mRNA
tin protoporphyrin IX inhibits the reaction [8-bromocyclic GMP results in increased expression of NRF1 mRNA]		 CTD PMID:24041027 NCBI chr 7:129,611,720...129,757,076
Ensembl chr 7:129,611,720...129,757,082 		JBrowse link
G PDE5A phosphodiesterase 5A multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with 8-bromocyclic GMP] results in increased expression of PDE5A protein; [1-Methyl-3-isobutylxanthine co-treated with 8-bromocyclic GMP] results in increased expression of PDE5A protein modified form CTD PMID:20613715 NCBI chr 4:119,494,403...119,628,804
Ensembl chr 4:119,494,397...119,628,804 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha increases expression
multiple interactions		 EXP 8-bromocyclic GMP results in increased expression of PPARGC1A mRNA
tin protoporphyrin IX inhibits the reaction [8-bromocyclic GMP results in increased expression of PPARGC1A mRNA]		 CTD PMID:24041027 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 increases expression
multiple interactions		 ISO
EXP		 8-bromocyclic GMP results in increased expression of PRKG1 protein
[8-bromocyclic GMP co-treated with PRKG1 protein co-treated with ARHGEF17 protein] results in increased activity of SRF protein		 CTD PMID:12620371 PMID:23195829 NCBI chr10:50,990,888...52,298,350
Ensembl chr10:50,990,888...52,298,423 		JBrowse link
G SCNN1B sodium channel epithelial 1 subunit beta multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with 8-bromocyclic GMP] results in increased expression of SCNN1B protein CTD PMID:20613715 NCBI chr16:23,278,231...23,381,294
Ensembl chr16:23,278,231...23,381,294 		JBrowse link
G SOD2 superoxide dismutase 2 increases expression ISO 8-bromocyclic GMP results in increased expression of SOD2 mRNA; 8-bromocyclic GMP results in increased expression of SOD2 protein CTD PMID:14996425 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SPP1 secreted phosphoprotein 1 multiple interactions ISO 8-bromocyclic GMP inhibits the reaction [Glucose results in increased secretion of SPP1 protein]; Dinitrochlorobenzene inhibits the reaction [8-bromocyclic GMP inhibits the reaction [Glucose results in increased secretion of SPP1 protein]]; KT 5823 inhibits the reaction [8-bromocyclic GMP inhibits the reaction [Glucose results in increased secretion of SPP1 protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [8-bromocyclic GMP inhibits the reaction [Glucose results in increased secretion of SPP1 protein]] CTD PMID:20453393 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532 		JBrowse link
G SRF serum response factor multiple interactions EXP [8-bromocyclic GMP co-treated with PRKG1 protein co-treated with ARHGEF17 protein] results in increased activity of SRF protein CTD PMID:23195829 NCBI chr 6:43,171,269...43,181,506
Ensembl chr 6:43,171,269...43,181,506 		JBrowse link
G TFAM transcription factor A, mitochondrial increases expression
multiple interactions		 EXP 8-bromocyclic GMP results in increased expression of TFAM mRNA
tin protoporphyrin IX inhibits the reaction [8-bromocyclic GMP results in increased expression of TFAM mRNA]		 CTD PMID:24041027 NCBI chr10:58,385,410...58,399,220
Ensembl chr10:58,385,345...58,399,220 		JBrowse link
G TH tyrosine hydroxylase multiple interactions ISO 8-bromocyclic GMP inhibits the reaction [[EDN1 protein binds to and results in increased activity of EDNRB protein] which results in decreased activity of TH protein]; 8-bromocyclic GMP inhibits the reaction [[EDN3 protein binds to and results in increased activity of EDNRB protein] which results in decreased activity of TH protein] CTD PMID:16023617 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO 8-bromocyclic GMP inhibits the reaction [TNF protein results in increased activity of CASP3 protein]; KT 5823 inhibits the reaction [8-bromocyclic GMP inhibits the reaction [TNF protein results in increased activity of CASP3 protein]] CTD PMID:9388267 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TP53 tumor protein p53 increases expression ISO 8-bromocyclic GMP results in increased expression of TP53 protein CTD PMID:9888876 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538 		JBrowse link
G TRPC6 transient receptor potential cation channel subfamily C member 6 multiple interactions
increases phosphorylation		 ISO
EXP		 8-bromocyclic GMP inhibits the reaction [1-oleoyl-2-acetylglycerol results in increased activity of TRPC6 protein]
8-bromocyclic GMP results in increased phosphorylation of TRPC6 protein
KT 5823 inhibits the reaction [8-bromocyclic GMP results in increased phosphorylation of TRPC6 protein]		 CTD PMID:20177073 NCBI chr11:101,451,564...101,584,007
Ensembl chr11:101,451,564...101,872,562 		JBrowse link
G TXN thioredoxin multiple interactions ISO 8-bromocyclic GMP inhibits the reaction [Glucose results in decreased expression of TXN1 protein] CTD PMID:20453393 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507 		JBrowse link
G UQCRC1 ubiquinol-cytochrome c reductase core protein 1 multiple interactions
increases expression		 EXP tin protoporphyrin IX inhibits the reaction [8-bromocyclic GMP results in increased expression of UQCRC1 protein] CTD PMID:24041027 NCBI chr 3:48,599,002...48,609,646
Ensembl chr 3:48,599,002...48,610,976 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 decreases expression EXP 8-bromocyclic GMP results in decreased expression of VCAM1 protein CTD PMID:17828804 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045 		JBrowse link
G VEGFA vascular endothelial growth factor A decreases expression EXP 8-bromocyclic GMP results in decreased expression of VEGFA protein CTD PMID:17828804 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
acetoacetyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSD17B2 hydroxysteroid 17-beta dehydrogenase 2 affects binding EXP acetoacetyl CoA binds to HSD17B2 protein CTD PMID:25526675 NCBI chr16:82,035,253...82,098,534
Ensembl chr16:82,035,004...82,098,534 		JBrowse link
acetyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACLY ATP citrate lyase increases abundance ISO ACLY protein results in increased abundance of Acetyl Coenzyme A CTD PMID:28077572 NCBI chr17:41,866,917...41,930,545
Ensembl chr17:41,866,917...41,930,542 		JBrowse link
G APP amyloid beta precursor protein affects localization
increases secretion
multiple interactions		 ISO
EXP		 APP protein affects the localization of Acetyl Coenzyme A
Acetyl Coenzyme A results in increased secretion of APP protein modified form
Acetyl Coenzyme A inhibits the reaction [Hydrogen Peroxide results in decreased secretion of APP protein modified form]
IL1B protein affects the reaction [APP protein affects the localization of Acetyl Coenzyme A]		 CTD PMID:16122837 PMID:22906069 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G CRAT carnitine O-acetyltransferase decreases activity ISO Acetyl Coenzyme A deficiency results in decreased activity of CRAT protein CTD PMID:8075222 NCBI chr 9:129,094,794...129,110,793
Ensembl chr 9:129,094,142...129,111,189 		JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor decreases abundance
multiple interactions		 EXP ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A
3-Hydroxybutyric Acid inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A]		 CTD PMID:25440059 NCBI chr10:49,434,881...49,539,538
Ensembl chr10:49,454,168...49,539,538 		JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO [Fluoxetine results in decreased expression of G6PC1 protein] which results in increased abundance of Acetyl Coenzyme A CTD PMID:33179799 NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO IL1B protein affects the reaction [APP protein affects the localization of Acetyl Coenzyme A] CTD PMID:16122837 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G KAT2B lysine acetyltransferase 2B affects binding ISO Acetyl Coenzyme A binds to KAT2B protein CTD PMID:28077572 NCBI chr 3:20,040,446...20,154,404
Ensembl chr 3:20,040,446...20,154,404 		JBrowse link
G METRNL meteorin like, glial cell differentiation regulator multiple interactions ISO METRNL protein inhibits the reaction [Dietary Fats results in decreased abundance of Acetyl Coenzyme A] CTD PMID:30213948 NCBI chr17:83,079,609...83,095,122
Ensembl chr17:83,079,609...83,095,122 		JBrowse link
G NAT1 N-acetyltransferase 1 multiple interactions
affects binding		 EXP [NQO1 protein co-treated with NADP co-treated with Acetyl Coenzyme A co-treated with NAT1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone; Acetyl Coenzyme A inhibits the reaction [Cyanamide results in decreased activity of NAT1 protein]; Acetyl Coenzyme A inhibits the reaction [Iodoacetamide results in decreased activity of NAT1 protein]
Acetyl Coenzyme A binds to NAT1 protein		 CTD PMID:20545351 PMID:22835378 NCBI chr 8:18,170,467...18,223,689
Ensembl chr 8:18,170,477...18,223,689 		JBrowse link
G NAT2 N-acetyltransferase 2 multiple interactions EXP [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]; [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone] CTD PMID:20545351 NCBI chr 8:18,386,301...18,401,218
Ensembl chr 8:18,391,282...18,401,218 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]; [NQO1 protein co-treated with NADP co-treated with Acetyl Coenzyme A co-treated with NAT1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone CTD PMID:20545351 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G SULT1A2 sulfotransferase family 1A member 2 multiple interactions EXP [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone] CTD PMID:20545351 NCBI chr16:28,591,943...28,597,050
Ensembl chr16:28,591,943...28,597,050 		JBrowse link
acryloyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ECHS1 enoyl-CoA hydratase, short chain 1 increases abundance EXP ECHS1 gene mutant form results in increased abundance of acryloyl-coenzyme A CTD PMID:25125611 NCBI chr10:133,362,485...133,373,354
Ensembl chr10:133,362,485...133,373,354 		JBrowse link
G HIBCH 3-hydroxyisobutyryl-CoA hydrolase increases abundance EXP HIBCH gene mutant form results in increased abundance of acryloyl-coenzyme A CTD PMID:25125611 NCBI chr 2:190,189,735...190,319,826
Ensembl chr 2:190,189,735...190,344,193 		JBrowse link
adenosine 3',5'-bismonophosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SULT1A1 sulfotransferase family 1A member 1 multiple interactions ISO Glutathione Disulfide affects the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT1A1 protein]; Glutathione Disulfide affects the reaction [Polychlorinated Biphenyls analog affects the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT1A1 protein]]; Polychlorinated Biphenyls analog affects the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT1A1 protein] CTD PMID:21130751 NCBI chr16:28,605,258...28,623,375
Ensembl chr16:28,605,196...28,610,044 		JBrowse link
G SULT1E1 sulfotransferase family 1E member 1 multiple interactions EXP [2,2',4,4'-tetrabromodiphenyl ether metabolite co-treated with adenosine 3'-phosphate-5'-phosphate] binds to SULT1E1 protein; [Estradiol co-treated with adenosine 3'-phosphate-5'-phosphate] binds to SULT1E1 protein; [tetrabromobisphenol A co-treated with adenosine 3'-phosphate-5'-phosphate] binds to SULT1E1 protein; Estradiol inhibits the reaction [[tetrabromobisphenol A co-treated with adenosine 3'-phosphate-5'-phosphate] binds to SULT1E1 protein]; tetrabromobisphenol A inhibits the reaction [[Estradiol co-treated with adenosine 3'-phosphate-5'-phosphate] binds to SULT1E1 protein] CTD PMID:23959441 NCBI chr 4:69,821,122...69,860,145
Ensembl chr 4:69,841,212...69,860,145 		JBrowse link
G SULT2A1 sulfotransferase family 2A member 1 affects binding
multiple interactions		 EXP adenosine 3'-phosphate-5'-phosphate binds to SULT2A1 protein
Benzoquinones analog inhibits the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT2A1 protein]; Dehydroepiandrosterone inhibits the reaction [Benzoquinones analog inhibits the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT2A1 protein]]		 CTD PMID:24059442 NCBI chr19:47,870,467...47,886,315
Ensembl chr19:47,870,467...47,886,315 		JBrowse link
adenosine 5'-(hexahydrogen pentaphosphate) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT10 nudix hydrolase 10 multiple interactions EXP [NUDT10 protein results in increased metabolism of diadenosine 5',5''''-P1,P6-hexaphosphate] which results in increased chemical synthesis of adenosine 5'-pentaphosphate CTD PMID:12121577 NCBI chr  X:51,332,231...51,337,525
Ensembl chr  X:51,332,231...51,337,525 		JBrowse link
G NUDT11 nudix hydrolase 11 multiple interactions EXP [NUDT11 protein results in increased metabolism of diadenosine 5',5''''-P1,P6-hexaphosphate] which results in increased chemical synthesis of adenosine 5'-pentaphosphate CTD PMID:12121577 NCBI chr  X:51,490,011...51,496,592
Ensembl chr  X:51,490,011...51,496,592 		JBrowse link
adenosine 5'-[gamma-thio]triphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD80 CD80 molecule increases expression ISO adenosine 5'-O-(3-thiotriphosphate) results in increased expression of CD80 protein CTD PMID:15944274 NCBI chr 3:119,524,293...119,559,614
Ensembl chr 3:119,524,293...119,559,614 		JBrowse link
G CD86 CD86 molecule increases expression ISO adenosine 5'-O-(3-thiotriphosphate) results in increased expression of CD86 protein CTD PMID:15944274 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP [adenosine 5'-O-(3-thiotriphosphate) binds to and results in increased activity of P2RY11 protein] which results in increased expression of CXCL8 protein CTD PMID:19815812 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G IL10 interleukin 10 decreases expression ISO adenosine 5'-O-(3-thiotriphosphate) results in decreased expression of IL10 protein CTD PMID:15944274 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL12B interleukin 12B increases expression ISO adenosine 5'-O-(3-thiotriphosphate) results in increased expression of IL12B protein CTD PMID:15944274 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G IL1B interleukin 1 beta increases expression ISO adenosine 5'-O-(3-thiotriphosphate) results in increased expression of IL1B protein CTD PMID:15944274 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G P2RX7 purinergic receptor P2X 7 affects response to substance ISO P2RX7 protein affects the susceptibility to adenosine 5'-O-(3-thiotriphosphate) CTD PMID:12873706 NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032 		JBrowse link
G P2RY11 purinergic receptor P2Y11 multiple interactions EXP [adenosine 5'-O-(3-thiotriphosphate) binds to and results in increased activity of P2RY11 protein] which results in increased expression of CXCL8 protein; adenosine 5'-O-(3-thiotriphosphate) binds to and results in increased activity of P2RY11 protein CTD PMID:19815812 NCBI chr19:10,111,693...10,115,372
Ensembl chr19:10,111,693...10,115,372 		JBrowse link
G PTGDR prostaglandin D2 receptor multiple interactions EXP adenosine 5'-O-(3-thiotriphosphate) inhibits the reaction [Prostaglandin D2 binds to PTGDR protein] CTD PMID:9579725 NCBI chr14:52,267,698...52,280,914
Ensembl chr14:52,267,698...52,276,724 		JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 increases activity
multiple interactions		 ISO adenosine 5'-O-(3-thiotriphosphate) results in increased activity of TRPV1 protein
Capsaicin promotes the reaction [adenosine 5'-O-(3-thiotriphosphate) results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [adenosine 5'-O-(3-thiotriphosphate) results in increased activity of TRPV1 protein]		 CTD PMID:11140687 NCBI chr17:3,565,446...3,609,411
Ensembl chr17:3,565,444...3,609,411 		JBrowse link
adenosine 5'-monophosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC9 ATP binding cassette subfamily C member 9 multiple interactions ISO Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]; Creatine metabolite inhibits the reaction [Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]] CTD PMID:11390963 NCBI chr12:21,797,389...21,941,426
Ensembl chr12:21,797,389...21,942,543 		JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 multiple interactions EXP [4-dimethylaminocinnamaldehyde co-treated with Adenosine Monophosphate] binds to ALDH1A1 protein CTD PMID:10609638 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442 		JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor increases abundance ISO ERCC6 gene mutant form results in increased abundance of Adenosine Monophosphate CTD PMID:25440059 NCBI chr10:49,434,881...49,539,538
Ensembl chr10:49,454,168...49,539,538 		JBrowse link
G H2AX H2A.X variant histone multiple interactions EXP Adenosine Monophosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form] CTD PMID:32941855 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 multiple interactions ISO Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]; Creatine metabolite inhibits the reaction [Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]] CTD PMID:11390963 NCBI chr11:17,385,248...17,389,346
Ensembl chr11:17,365,172...17,389,331 		JBrowse link
G NUDT10 nudix hydrolase 10 multiple interactions EXP [NUDT10 protein results in increased metabolism of diadenosine 5',5''''-P1,P6-hexaphosphate] which results in increased chemical synthesis of Adenosine Monophosphate; [NUDT10 protein results in increased metabolism of P(1),P(5)-di(adenosine-5'-)pentaphosphate] which results in increased chemical synthesis of Adenosine Monophosphate CTD PMID:12121577 NCBI chr  X:51,332,231...51,337,525
Ensembl chr  X:51,332,231...51,337,525 		JBrowse link
G NUDT11 nudix hydrolase 11 multiple interactions EXP [NUDT11 protein results in increased metabolism of diadenosine 5',5''''-P1,P6-hexaphosphate] which results in increased chemical synthesis of Adenosine Monophosphate; [NUDT11 protein results in increased metabolism of P(1),P(5)-di(adenosine-5'-)pentaphosphate] which results in increased chemical synthesis of Adenosine Monophosphate CTD PMID:12121577 NCBI chr  X:51,490,011...51,496,592
Ensembl chr  X:51,490,011...51,496,592 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha increases expression EXP Adenosine Monophosphate results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G TP53BP1 tumor protein p53 binding protein 1 multiple interactions EXP Adenosine Monophosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein] CTD PMID:32941855 NCBI chr15:43,403,061...43,510,640
Ensembl chr15:43,403,061...43,510,728 		JBrowse link
G TP73 tumor protein p73 affects abundance ISO TP73 protein affects the abundance of Adenosine Monophosphate CTD PMID:25554796 NCBI chr 1:3,652,516...3,736,201
Ensembl chr 1:3,652,516...3,736,201 		JBrowse link
ADP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) multiple interactions
affects binding		 EXP estradiol-17 beta-glucuronide inhibits the reaction [Adenosine Diphosphate binds to ABCC1 protein mutant form]; estradiol-17 beta-glucuronide inhibits the reaction [Adenosine Diphosphate binds to ABCC1 protein]; Vanadates promotes the reaction [Adenosine Diphosphate binds to ABCC1 protein]
Adenosine Diphosphate binds to ABCC1 protein; Adenosine Diphosphate binds to ABCC1 protein mutant form		 CTD PMID:18336795 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257 		JBrowse link
G AHR aryl hydrocarbon receptor multiple interactions ISO Adenosine Diphosphate affects the folding of [Tetrachlorodibenzodioxin binds to AHR protein] CTD PMID:1848756 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G AK1 adenylate kinase 1 increases abundance ISO AK1 protein results in increased abundance of Adenosine Diphosphate CTD PMID:11390963 NCBI chr 9:127,866,480...127,879,621
Ensembl chr 9:127,866,486...127,877,675 		JBrowse link
G ALB albumin decreases secretion
multiple interactions		 EXP Adenosine Diphosphate results in decreased secretion of ALB protein
Aspirin inhibits the reaction [Adenosine Diphosphate results in decreased secretion of ALB protein]		 CTD PMID:17303692 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G AXL AXL receptor tyrosine kinase decreases response to substance EXP AXL protein results in decreased susceptibility to Adenosine Diphosphate CTD PMID:15733062 NCBI chr19:41,219,223...41,261,766
Ensembl chr19:41,219,223...41,261,766 		JBrowse link
G CAT catalase multiple interactions ISO CAT protein inhibits the reaction [Adenosine Diphosphate results in increased glutathionylation of PTPN1 protein] CTD PMID:16781456 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CD40LG CD40 ligand increases expression
multiple interactions		 EXP
ISO		 Adenosine Diphosphate results in increased expression of CD40LG protein
clopidogrel inhibits the reaction [Adenosine Diphosphate results in increased expression of CD40LG protein]		 CTD PMID:11297035 PMID:17043144 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390 		JBrowse link
G CFTR CF transmembrane conductance regulator multiple interactions EXP Adenosine Diphosphate binds to and results in decreased activity of CFTR protein; P(1),P(5)-di(adenosine-5'-)pentaphosphate inhibits the reaction [Adenosine Diphosphate binds to and results in decreased activity of CFTR protein] CTD PMID:15684079 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971 		JBrowse link
G CHORDC1 cysteine and histidine rich domain containing 1 multiple interactions ISO Adenosine Diphosphate binds to and affects the folding of CHORDC1 protein; Adenosine Diphosphate promotes the reaction [CHORDC1 protein binds to CHORDC1 protein]; Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to CHORDC1 protein] CTD PMID:23184943 NCBI chr11:90,200,429...90,223,049
Ensembl chr11:90,200,429...90,223,077 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 multiple interactions EXP CYP2C19 gene affects the susceptibility to [Adenosine Diphosphate co-treated with clopidogrel]; CYP2C19 gene SNP affects the reaction [Adenosine Diphosphate results in increased expression of SELP protein]; CYP2C19 gene SNP affects the susceptibility to [Adenosine Diphosphate co-treated with Arachidonic Acid] CTD PMID:16772608 PMID:18004210 PMID:18394438 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547 		JBrowse link
G DTYMK deoxythymidylate kinase multiple interactions EXP DTYMK protein binds to [N1-(4-bis(pivaloyloxymethyl)phosphinylbuten-2-yl)thymine co-treated with Adenosine Diphosphate] CTD PMID:21128666 NCBI chr 2:241,675,747...241,686,815
Ensembl chr 2:241,675,747...241,686,944 		JBrowse link
G DUSP1 dual specificity phosphatase 1 multiple interactions EXP Adenosine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of DUSP1 protein]; Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in decreased expression of DUSP1 protein]] CTD PMID:32941855 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195 		JBrowse link
G DUSP6 dual specificity phosphatase 6 multiple interactions EXP Adenosine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of DUSP6 protein]; Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in decreased expression of DUSP6 protein]] CTD PMID:32941855 NCBI chr12:89,347,235...89,352,501
Ensembl chr12:89,347,235...89,352,501 		JBrowse link
G EPHA4 EPH receptor A4 increases phosphorylation
multiple interactions		 EXP Adenosine Diphosphate results in increased phosphorylation of EPHA4 protein
Benzoic Acid analog inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of EPHA4 protein]		 CTD PMID:22273509 NCBI chr 2:221,418,027...221,574,202
Ensembl chr 2:221,418,027...221,574,202 		JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
decreases activity		 ISO Adenosine Diphosphate inhibits the reaction [ERN1 protein binds to ERN1 protein]
Adenosine Diphosphate results in decreased activity of ERN1 protein		 CTD PMID:25164867 NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819 		JBrowse link
G F2 coagulation factor II, thrombin increases abundance
multiple interactions		 EXP F2 protein results in increased abundance of Adenosine Diphosphate
Quercetin inhibits the reaction [F2 protein results in increased abundance of Adenosine Diphosphate]; resveratrol inhibits the reaction [F2 protein results in increased abundance of Adenosine Diphosphate]		 CTD PMID:15342215 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506 		JBrowse link
G FGA fibrinogen alpha chain multiple interactions
increases secretion		 EXP Aspirin promotes the reaction [Adenosine Diphosphate results in increased secretion of FGA protein] CTD PMID:17303692 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742 		JBrowse link
G FGB fibrinogen beta chain decreases secretion
multiple interactions		 EXP Adenosine Diphosphate results in decreased secretion of FGB protein
Aspirin inhibits the reaction [Adenosine Diphosphate results in decreased secretion of FGB protein]		 CTD PMID:17303692 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807 		JBrowse link
G FGG fibrinogen gamma chain increases secretion
multiple interactions		 EXP Adenosine Diphosphate results in increased secretion of FGG protein
Aspirin promotes the reaction [Adenosine Diphosphate results in increased secretion of FGG protein]		 CTD PMID:17303692 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase multiple interactions EXP Adenosine Diphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog] CTD PMID:15788719 NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374 		JBrowse link
G GAS6 growth arrest specific 6 increases response to substance EXP GAS6 protein results in increased susceptibility to Adenosine Diphosphate CTD PMID:15733062 NCBI chr13:113,820,549...113,864,076
Ensembl chr13:113,820,549...113,864,076 		JBrowse link
G H2AX H2A.X variant histone multiple interactions EXP Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]; Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]]; U 0126 inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]] CTD PMID:32941855 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465 		JBrowse link
G HRAS HRas proto-oncogene, GTPase multiple interactions EXP Adenosine Diphosphate binds to and affects the folding of HRAS protein CTD PMID:16388579 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]; Calcium promotes the reaction [Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]] CTD PMID:23184943 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699 		JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 increases abundance
multiple interactions		 ISO IDH2 protein mutant form results in increased abundance of Adenosine Diphosphate
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Adenosine Diphosphate]		 CTD PMID:27469509 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477 		JBrowse link
G IL6 interleukin 6 increases expression
multiple interactions		 ISO Adenosine Diphosphate results in increased expression of IL6 protein
MRS 2211 inhibits the reaction [Adenosine Diphosphate results in increased expression of IL6 protein]		 CTD PMID:24849676 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G ITGA2 integrin subunit alpha 2 multiple interactions EXP ITGA2 gene SNP affects the susceptibility to [Aspirin co-treated with clopidogrel co-treated with Adenosine Diphosphate] CTD PMID:16214444 NCBI chr 5:52,989,352...53,094,779
Ensembl chr 5:52,989,340...53,094,779 		JBrowse link
G ITGA2B integrin subunit alpha 2b multiple interactions EXP cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]] CTD PMID:18404433 NCBI chr17:44,372,181...44,389,649
Ensembl chr17:44,372,180...44,389,649 		JBrowse link
G ITGB1BP2 integrin subunit beta 1 binding protein 2 multiple interactions ISO Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to CHORDC1 protein]; Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]; Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to ITGB1BP2 protein]; Calcium promotes the reaction [Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]] CTD PMID:23184943 NCBI chr  X:71,301,750...71,305,371
Ensembl chr  X:71,301,750...71,305,371 		JBrowse link
G ITGB3 integrin subunit beta 3 multiple interactions EXP cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]] CTD PMID:18404433 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,827...47,313,743 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 increases phosphorylation
multiple interactions		 EXP Adenosine Diphosphate results in increased phosphorylation of MAPK1 protein
Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased phosphorylation of MAPK1 protein]]		 CTD PMID:15034929 PMID:32941855 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 increases phosphorylation
multiple interactions		 EXP Adenosine Diphosphate results in increased phosphorylation of MAPK3 protein
Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased phosphorylation of MAPK3 protein]]		 CTD PMID:15034929 PMID:32941855 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions EXP Dicumarol inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of MAPK8 protein] CTD PMID:24466103 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 multiple interactions EXP Dicumarol inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of MAPK9 protein] CTD PMID:24466103 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099 		JBrowse link
G MERTK MER proto-oncogene, tyrosine kinase increases response to substance EXP MERTK protein results in increased susceptibility to Adenosine Diphosphate CTD PMID:15733062 NCBI chr 2:111,898,607...112,029,561
Ensembl chr 2:111,898,607...112,029,561 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO NOS2 protein affects the susceptibility to [Phenylephrine co-treated with Adenosine Diphosphate] CTD PMID:11498454 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NT5E 5'-nucleotidase ecto decreases activity EXP Adenosine Diphosphate analog results in decreased activity of NT5E protein CTD PMID:18404487 NCBI chr 6:85,450,083...85,495,784
Ensembl chr 6:85,449,584...85,495,791 		JBrowse link
G P2RY12 purinergic receptor P2Y12 affects response to substance
increases response to substance
multiple interactions		 EXP
ISO		 P2RY12 gene polymorphism affects the susceptibility to Adenosine Diphosphate; P2RY12 protein affects the susceptibility to Adenosine Diphosphate
P2RY12 protein results in increased susceptibility to Adenosine Diphosphate
Epinephrine inhibits the reaction [P2RY12 gene mutant form results in decreased susceptibility to Adenosine Diphosphate]
P2RY12 protein affects the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]		 CTD PMID:11196645 PMID:11413167 PMID:18404433 PMID:23849096 NCBI chr 3:151,336,843...151,384,753
Ensembl chr 3:151,336,843...151,384,753 		JBrowse link
G PDGFB platelet derived growth factor subunit B increases secretion
multiple interactions		 EXP Adenosine Diphosphate results in increased secretion of PDGFB protein
Aspirin promotes the reaction [Adenosine Diphosphate results in increased secretion of PDGFB protein]		 CTD PMID:17303692 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982 		JBrowse link
G PF4 platelet factor 4 increases secretion
multiple interactions		 EXP Adenosine Diphosphate results in increased secretion of PF4 protein
silidianin inhibits the reaction [Adenosine Diphosphate results in increased secretion of PF4 protein]; Silybin inhibits the reaction [Adenosine Diphosphate results in increased secretion of PF4 protein]; silychristin inhibits the reaction [Adenosine Diphosphate results in increased secretion of PF4 protein]		 CTD PMID:19428933 PMID:29439388 NCBI chr 4:73,980,811...73,982,124
Ensembl chr 4:73,980,811...73,982,027 		JBrowse link
G PFKM phosphofructokinase, muscle multiple interactions EXP Adenosine Diphosphate inhibits the reaction [resveratrol results in decreased activity of PFKM protein] CTD PMID:23454376 NCBI chr12:48,105,353...48,146,404
Ensembl chr12:48,105,139...48,146,404 		JBrowse link
G PGP phosphoglycolate phosphatase decreases phosphorylation ISO PGP protein results in decreased phosphorylation of Adenosine Diphosphate CTD PMID:24338473 NCBI chr16:2,211,593...2,214,840
Ensembl chr16:2,211,593...2,214,840 		JBrowse link
G PPBP pro-platelet basic protein increases secretion EXP Adenosine Diphosphate results in increased secretion of PPBP protein CTD PMID:19428933 NCBI chr 4:73,986,439...73,988,190
Ensembl chr 4:73,986,439...73,988,190 		JBrowse link
G PPP5C protein phosphatase 5 catalytic subunit multiple interactions EXP Adenosine Diphosphate binds to and affects the folding of PPP5C protein CTD PMID:23184943 NCBI chr19:46,347,087...46,390,975
Ensembl chr19:46,347,087...46,392,981 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 increases glutathionylation
multiple interactions		 ISO Adenosine Diphosphate results in increased glutathionylation of PTPN1 protein
CAT protein inhibits the reaction [Adenosine Diphosphate results in increased glutathionylation of PTPN1 protein]		 CTD PMID:16781456 NCBI chr20:50,510,383...50,585,241
Ensembl chr20:50,510,321...50,585,241 		JBrowse link
G SELP selectin P multiple interactions
increases expression		 EXP cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]; CYP2C19 gene SNP affects the reaction [Adenosine Diphosphate results in increased expression of SELP protein]; Heparin promotes the reaction [Adenosine Diphosphate affects the localization of SELP protein]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]]; P2RY12 protein affects the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]; Quercetin inhibits the reaction [Adenosine Diphosphate results in increased expression of SELP protein] CTD PMID:9740346 PMID:18394438 PMID:18404433 PMID:23249183 NCBI chr 1:169,588,849...169,630,124
Ensembl chr 1:169,588,849...169,630,193 		JBrowse link
G SIRT3 sirtuin 3 decreases abundance ISO SIRT3 protein results in decreased abundance of Adenosine Diphosphate CTD PMID:23166782 NCBI chr11:215,030...236,931
Ensembl chr11:215,030...236,931 		JBrowse link
G TALDO1 transaldolase 1 increases abundance ISO TALDO1 gene mutant form results in increased abundance of Adenosine Diphosphate CTD PMID:19436114 NCBI chr11:747,464...765,012
Ensembl chr11:747,415...765,012 		JBrowse link
G THBS1 thrombospondin 1 increases secretion EXP Adenosine Diphosphate results in increased secretion of THBS1 protein CTD PMID:17303692 NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466 		JBrowse link
G TP53BP1 tumor protein p53 binding protein 1 multiple interactions EXP Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]; Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]]; U 0126 inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]] CTD PMID:32941855 NCBI chr15:43,403,061...43,510,640
Ensembl chr15:43,403,061...43,510,728 		JBrowse link
G TYRO3 TYRO3 protein tyrosine kinase increases response to substance EXP TYRO3 protein results in increased susceptibility to Adenosine Diphosphate CTD PMID:15733062 NCBI chr15:41,559,212...41,583,589
Ensembl chr15:41,557,675...41,583,589 		JBrowse link
G VASP vasodilator stimulated phosphoprotein multiple interactions
increases phosphorylation		 EXP N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of VASP protein] CTD PMID:25329809 NCBI chr19:45,507,479...45,526,983
Ensembl chr19:45,506,579...45,526,989 		JBrowse link
ADP-D-ribose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADPRH ADP-ribosylarginine hydrolase increases hydrolysis EXP ADPRH protein results in increased hydrolysis of Adenosine Diphosphate Ribose metabolite CTD PMID:21498885 NCBI chr 3:119,579,492...119,589,945
Ensembl chr 3:119,579,268...119,589,945 		JBrowse link
G ADPRS ADP-ribosylserine hydrolase increases hydrolysis
multiple interactions		 EXP ADPRS protein results in increased hydrolysis of Adenosine Diphosphate Ribose metabolite
Adenosine Diphosphate Ribose inhibits the reaction [ADPRS protein results in increased hydrolysis of O-Acetyl-ADP-Ribose]		 CTD PMID:21498885 NCBI chr 1:36,088,892...36,093,932
Ensembl chr 1:36,088,892...36,093,932 		JBrowse link
G NOS1 nitric oxide synthase 1 multiple interactions ISO NOS1 protein affects the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased ribosylation of Adenosine Diphosphate Ribose] CTD PMID:10318960 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170 		JBrowse link
G TRPM2 transient receptor potential cation channel subfamily M member 2 multiple interactions
increases activity		 ISO
EXP		 Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]; Clotrimazole inhibits the reaction [Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]]; Flufenamic Acid inhibits the reaction [Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]]
Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein
2-aminoethoxydiphenyl borate inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; 4-amylcinnamoylanthranilic acid inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; 4-amylcinnamoylanthranilic acid inhibits the reaction [Cisplatin promotes the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]]; 4-amylcinnamoylanthranilic acid inhibits the reaction [Eicosapentaenoic Acid promotes the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]]; 4-amylcinnamoylanthranilic acid inhibits the reaction [Eicosapentaenoic Acid promotes the reaction [Cisplatin promotes the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]]]; Cisplatin promotes the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Copper Sulfate inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Eicosapentaenoic Acid promotes the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Eicosapentaenoic Acid promotes the reaction [Cisplatin promotes the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]]; ferrous chloride inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; lead nitrate inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Mercuric Chloride inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Miconazole inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Selenium Oxides inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]
4-amylcinnamoylanthranilic acid inhibits the reaction [[Buthionine Sulfoximine co-treated with Adenosine Diphosphate Ribose] results in increased activity of TRPM2 protein]; 4-amylcinnamoylanthranilic acid inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; [Buthionine Sulfoximine co-treated with Adenosine Diphosphate Ribose] results in increased activity of TRPM2 protein; Glutathione inhibits the reaction [[Buthionine Sulfoximine co-treated with Adenosine Diphosphate Ribose] results in increased activity of TRPM2 protein]; Glutathione inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; TRPM2 protein promotes the reaction [Adenosine Diphosphate Ribose results in increased uptake of Calcium]		 CTD PMID:18204483 PMID:20878536 PMID:21900507 PMID:22750002 PMID:33309544 More... NCBI chr21:44,353,621...44,442,644
Ensembl chr21:44,350,163...44,443,081 		JBrowse link
AICA ribonucleotide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB11 ATP binding cassette subfamily B member 11 decreases expression ISO AICA ribonucleotide results in decreased expression of ABCB11 mRNA CTD PMID:27090119 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 decreases expression ISO AICA ribonucleotide results in decreased expression of ABCC2 mRNA CTD PMID:27090119 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase multiple interactions EXP AICA ribonucleotide promotes the reaction [ABL1 protein mutant form binds to BECN1 protein]; AICA ribonucleotide promotes the reaction [ABL1 protein mutant form binds to XPO1 protein]; AICA ribonucleotide promotes the reaction [ABL1 protein mutant form binds to YWHAQ protein]; AICA ribonucleotide results in decreased expression of and affects the localization of ABL1 protein mutant form CTD PMID:33070465 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,043...130,887,675 		JBrowse link
G ACACA acetyl-CoA carboxylase alpha increases phosphorylation
multiple interactions
increases expression		 EXP
ISO		 AICA ribonucleotide results in increased phosphorylation of ACACA protein
AICA ribonucleotide inhibits the reaction [fipronil results in increased expression of and results in decreased phosphorylation of ACACA protein]; AICA ribonucleotide results in decreased expression of and results in increased phosphorylation of ACACA protein
AICA ribonucleotide results in increased expression of ACACA protein modified form		 CTD PMID:15297373 PMID:16020477 PMID:16873680 PMID:20080969 PMID:25743752 More... NCBI chr17:37,084,992...37,406,836
Ensembl chr17:37,084,992...37,406,836 		JBrowse link
G ACACB acetyl-CoA carboxylase beta increases phosphorylation EXP AICA ribonucleotide results in increased phosphorylation of ACACB protein CTD PMID:16873680 NCBI chr12:109,111,189...109,268,226
Ensembl chr12:109,116,587...109,268,226 		JBrowse link
G ACADM acyl-CoA dehydrogenase medium chain multiple interactions
increases expression		 ISO
EXP		 AICA ribonucleotide inhibits the reaction [Phenylephrine results in decreased expression of ACADM mRNA]
AICA ribonucleotide results in increased expression of ACADM mRNA; AICA ribonucleotide results in increased expression of ACADM protein		 CTD PMID:19699196 PMID:25743752 NCBI chr 1:75,724,709...75,763,679
Ensembl chr 1:75,724,431...75,787,575 		JBrowse link
G ACTA2 actin alpha 2, smooth muscle multiple interactions EXP AICA ribonucleotide inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein] CTD PMID:27688165 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,935,074...88,991,339 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing increases expression
multiple interactions		 ISO AICA ribonucleotide results in increased expression of ADIPOQ protein
AICA ribonucleotide inhibits the reaction [Palmitic Acid results in decreased expression of ADIPOQ mRNA]		 CTD PMID:20980258 PMID:25108154 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions ISO AICA ribonucleotide inhibits the reaction [AKT1 protein mutant form results in decreased oxidation of Fatty Acids]; AICA ribonucleotide inhibits the reaction [AKT1 protein mutant form results in increased phosphorylation of EIF4EBP1 protein]; AICA ribonucleotide inhibits the reaction [AKT1 protein mutant form results in increased susceptibility to Glucose deficiency]; PRKAA2 protein affects the reaction [AICA ribonucleotide inhibits the reaction [AKT1 protein mutant form affects the susceptibility to Glucose deficiency]] CTD PMID:15806154 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G APP amyloid beta precursor protein decreases expression EXP AICA ribonucleotide results in decreased expression of APP protein modified form CTD PMID:20080969 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G ARG1 arginase 1 multiple interactions ISO AICA ribonucleotide inhibits the reaction [Palmitic Acid results in decreased expression of ARG1 mRNA] CTD PMID:25108154 NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332 		JBrowse link
G ATG5 autophagy related 5 multiple interactions EXP AICA ribonucleotide inhibits the reaction [Ethanol results in decreased expression of ATG5 protein] CTD PMID:24582693 NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791 		JBrowse link
G BECN1 beclin 1 increases expression
multiple interactions		 ISO
EXP		 AICA ribonucleotide results in increased expression of BECN1 protein
AICA ribonucleotide promotes the reaction [ABL1 protein mutant form binds to BECN1 protein]; AICA ribonucleotide promotes the reaction [XPO1 protein binds to BECN1 protein]; AICA ribonucleotide results in increased expression of and affects the localization of BECN1 protein
AICA ribonucleotide promotes the reaction [4-nonylphenol results in increased expression of BECN1 protein]		 CTD PMID:28041982 PMID:33070465 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350 		JBrowse link
G CASP3 caspase 3 increases activity
multiple interactions		 ISO
EXP		 AICA ribonucleotide results in increased activity of CASP3 protein
AICA ribonucleotide inhibits the reaction [sunitinib results in increased cleavage of CASP3 protein]		 CTD PMID:16469385 PMID:21906609 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP7 caspase 7 multiple interactions EXP AICA ribonucleotide inhibits the reaction [sunitinib results in increased cleavage of CASP7 protein] CTD PMID:21906609 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907 		JBrowse link
G CASP9 caspase 9 increases activity ISO AICA ribonucleotide results in increased activity of CASP9 protein CTD PMID:16469385 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAT catalase multiple interactions
increases expression		 EXP AICA ribonucleotide promotes the reaction [FOXO1 protein results in increased expression of CAT mRNA]
AICA ribonucleotide results in increased expression of CAT mRNA; AICA ribonucleotide results in increased expression of CAT protein		 CTD PMID:25065674 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions
decreases expression		 ISO AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of CCL2 mRNA]
AICA ribonucleotide results in decreased expression of CCL2 mRNA
AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; dorsomorphin inhibits the reaction [AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]]; dorsomorphin inhibits the reaction [AICA ribonucleotide results in decreased expression of CCL2 mRNA]		 CTD PMID:24465016 PMID:25108154 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 multiple interactions EXP AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of CCL3 mRNA] CTD PMID:21745629 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G CCNA2 cyclin A2 multiple interactions
decreases expression		 EXP AICA ribonucleotide inhibits the reaction [ELAVL1 protein binds to CCNA2 3' UTR]
AICA ribonucleotide results in decreased expression of CCNA2 mRNA; AICA ribonucleotide results in decreased expression of CCNA2 protein		 CTD PMID:12730239 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883 		JBrowse link
G CCNB1 cyclin B1 multiple interactions
decreases expression		 EXP AICA ribonucleotide inhibits the reaction [ELAVL1 protein binds to CCNB1 3' UTR]
AICA ribonucleotide results in decreased expression of CCNB1 mRNA; AICA ribonucleotide results in decreased expression of CCNB1 protein		 CTD PMID:12730239 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) multiple interactions EXP AICA ribonucleotide results in increased expression of and affects the localization of CD36 protein CTD PMID:28038998 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G CEBPA CCAAT enhancer binding protein alpha decreases expression
multiple interactions		 ISO AICA ribonucleotide results in decreased expression of CEBPA protein
AICA ribonucleotide inhibits the reaction [fipronil results in increased expression of CEBPA protein]		 CTD PMID:27103584 NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534 		JBrowse link
G CEBPB CCAAT enhancer binding protein beta increases phosphorylation EXP AICA ribonucleotide results in increased phosphorylation of CEBPB protein CTD PMID:28038998 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668 		JBrowse link
G CFTR CF transmembrane conductance regulator multiple interactions ISO AICA ribonucleotide inhibits the reaction [Colforsin results in increased activity of CFTR protein] CTD PMID:12519745 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971 		JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions EXP AICA ribonucleotide inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein] CTD PMID:27688165 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A increases expression
multiple interactions		 EXP
ISO		 AICA ribonucleotide results in increased expression of CPT1A mRNA; AICA ribonucleotide results in increased expression of CPT1A protein
AICA ribonucleotide inhibits the reaction [TP53 gene mutant form results in increased expression of CPT1A protein]
dorsomorphin inhibits the reaction [AICA ribonucleotide results in increased expression of CPT1A mRNA]		 CTD PMID:24465016 PMID:25743752 PMID:33070465 NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410 		JBrowse link
G CPT1B carnitine palmitoyltransferase 1B multiple interactions ISO AICA ribonucleotide inhibits the reaction [Phenylephrine results in decreased expression of CPT1B mRNA]; AICA ribonucleotide inhibits the reaction [Phenylephrine results in decreased expression of CPT1B protein] CTD PMID:19699196 NCBI chr22:50,568,861...50,578,612
Ensembl chr22:50,568,861...50,578,465 		JBrowse link
G CTNNB1 catenin beta 1 multiple interactions
increases expression		 ISO [AICA ribonucleotide results in increased phosphorylation of HDAC5 protein] which results in increased expression of CTNNB1 mRNA; [AICA ribonucleotide results in increased phosphorylation of HDAC5 protein] which results in increased expression of CTNNB1 protein; AICA ribonucleotide inhibits the reaction [[HDAC5 protein binds to MEF2 protein] which binds to CTNNB1 promoter]; PRKAA2 protein affects the reaction [AICA ribonucleotide results in increased expression of CTNNB1 mRNA]; PRKAA2 protein affects the reaction [AICA ribonucleotide results in increased expression of CTNNB1 protein]
AICA ribonucleotide results in increased expression of CTNNB1 mRNA; AICA ribonucleotide results in increased expression of CTNNB1 protein		 CTD PMID:21454484 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of CXCL8 mRNA] CTD PMID:21745629 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYBA cytochrome b-245 alpha chain multiple interactions ISO AICA ribonucleotide inhibits the reaction [Cadmium Chloride results in increased expression of CYBA protein] CTD PMID:21195169 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G CYBB cytochrome b-245 beta chain multiple interactions ISO AICA ribonucleotide inhibits the reaction [Cadmium Chloride results in increased expression of CYBB protein] CTD PMID:21195169 NCBI chr  X:37,780,059...37,813,461
Ensembl chr  X:37,780,018...37,813,461 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 multiple interactions ISO AICA ribonucleotide promotes the reaction [NR1I3 protein results in increased expression of CYP2B10 mRNA]; PRKAA2 protein promotes the reaction [AICA ribonucleotide promotes the reaction [NR1I3 protein results in increased expression of CYP2B10 mRNA]] CTD PMID:22815988 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398 		JBrowse link
G CYP4F2 cytochrome P450 family 4 subfamily F member 2 multiple interactions
increases expression		 EXP dorsomorphin inhibits the reaction [AICA ribonucleotide results in increased expression of CYP4F2 mRNA]; PRKAA1 protein affects the reaction [AICA ribonucleotide results in increased expression of CYP4F2 mRNA]; PRKAA2 protein affects the reaction [AICA ribonucleotide results in increased expression of CYP4F2 mRNA] CTD PMID:21205922 NCBI chr19:15,878,023...15,898,074
Ensembl chr19:15,878,023...15,898,077 		JBrowse link
G EGFR epidermal growth factor receptor multiple interactions EXP AICA ribonucleotide inhibits the reaction [EGFR protein results in increased import of Deoxyglucose] CTD PMID:19625624 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha decreases phosphorylation EXP AICA ribonucleotide results in decreased phosphorylation of EIF2S1 protein CTD PMID:22898769 NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,328...67,386,516 		JBrowse link
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
decreases phosphorylation		 ISO AICA ribonucleotide inhibits the reaction [AKT1 protein mutant form results in increased phosphorylation of EIF4EBP1 protein]
AICA ribonucleotide results in decreased phosphorylation of EIF4EBP1 protein
AICA ribonucleotide inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EIF4EBP1 protein]		 CTD PMID:15806154 PMID:21195169 PMID:28041982 NCBI chr 8:38,030,534...38,060,365
Ensembl chr 8:38,030,534...38,060,365 		JBrowse link
G ELAVL1 ELAV like RNA binding protein 1 multiple interactions
decreases localization		 EXP AICA ribonucleotide inhibits the reaction [ELAVL1 protein binds to CCNA2 3' UTR]; AICA ribonucleotide inhibits the reaction [ELAVL1 protein binds to CCNB1 3' UTR]
AICA ribonucleotide results in decreased localization of ELAVL1 protein		 CTD PMID:12730239 NCBI chr19:7,958,573...8,005,641
Ensembl chr19:7,958,573...8,005,659 		JBrowse link
G FOXO1 forkhead box O1 multiple interactions
increases expression
increases phosphorylation
increases activity		 EXP AICA ribonucleotide promotes the reaction [FOXO1 protein results in increased expression of CAT mRNA]; AICA ribonucleotide promotes the reaction [FOXO1 protein results in increased expression of SOD2 mRNA]
AICA ribonucleotide results in increased expression of FOXO1 protein
AICA ribonucleotide results in increased phosphorylation of FOXO1 protein
AICA ribonucleotide results in increased activity of FOXO1 protein		 CTD PMID:25065674 NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641 		JBrowse link
G FSHB follicle stimulating hormone subunit beta multiple interactions ISO AICA ribonucleotide inhibits the reaction [[IGF1 protein co-treated with FSHB protein] results in increased phosphorylation of MAPK1 protein]; AICA ribonucleotide inhibits the reaction [[IGF1 protein co-treated with FSHB protein] results in increased phosphorylation of MAPK3 protein]; AICA ribonucleotide inhibits the reaction [FSHB protein results in increased phosphorylation of MAPK3 protein] CTD PMID:16020477 NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261 		JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 decreases expression ISO AICA ribonucleotide results in decreased expression of G6PC1 mRNA CTD PMID:19664596 NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438 		JBrowse link
G GPR68 G protein-coupled receptor 68 multiple interactions EXP AICA ribonucleotide inhibits the reaction [TNF protein promotes the reaction [Oxygen deficiency results in increased expression of GPR68 mRNA]]; AICA ribonucleotide inhibits the reaction [TNF protein results in increased expression of GPR68 mRNA] CTD PMID:28174749 NCBI chr14:91,232,532...91,270,790
Ensembl chr14:91,232,532...91,253,925 		JBrowse link
G GRB2 growth factor receptor bound protein 2 multiple interactions ISO GRB2 protein affects the reaction [AICA ribonucleotide results in increased activity of PRKCZ protein] CTD PMID:11978788 NCBI chr17:75,318,076...75,405,678
Ensembl chr17:75,318,076...75,405,709 		JBrowse link
G GSTK1 glutathione S-transferase kappa 1 increases expression ISO AICA ribonucleotide results in increased expression of GSTK1 protein CTD PMID:20980258 NCBI chr 7:143,263,441...143,269,115
Ensembl chr 7:143,244,093...143,270,854 		JBrowse link
G HDAC5 histone deacetylase 5 multiple interactions
increases phosphorylation		 ISO [AICA ribonucleotide results in increased phosphorylation of HDAC5 protein] which results in increased expression of CTNNB1 mRNA; [AICA ribonucleotide results in increased phosphorylation of HDAC5 protein] which results in increased expression of CTNNB1 protein; AICA ribonucleotide inhibits the reaction [[HDAC5 protein binds to MEF2 protein] which binds to CTNNB1 promoter] CTD PMID:21454484 NCBI chr17:44,076,753...44,123,641
Ensembl chr17:44,076,746...44,123,702 		JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha decreases expression ISO AICA ribonucleotide results in decreased expression of HNF4A mRNA CTD PMID:24428821 NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,699...44,432,845 		JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO AICA ribonucleotide results in decreased expression of HSD3B1 mRNA; AICA ribonucleotide results in decreased expression of HSD3B1 protein CTD PMID:16020477 NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054 		JBrowse link
G IGF1 insulin like growth factor 1 multiple interactions ISO AICA ribonucleotide inhibits the reaction [[IGF1 protein co-treated with FSHB protein] results in increased phosphorylation of MAPK1 protein]; AICA ribonucleotide inhibits the reaction [[IGF1 protein co-treated with FSHB protein] results in increased phosphorylation of MAPK3 protein]; AICA ribonucleotide inhibits the reaction [IGF1 protein results in increased phosphorylation of MAPK1 protein] CTD PMID:16020477 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G IL1B interleukin 1 beta multiple interactions
decreases expression		 ISO AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; dorsomorphin inhibits the reaction [AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]; dorsomorphin inhibits the reaction [AICA ribonucleotide results in decreased expression of IL1B mRNA] CTD PMID:24465016 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions
decreases expression		 ISO AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]
AICA ribonucleotide results in decreased expression of IL6 mRNA
AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; dorsomorphin inhibits the reaction [AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; dorsomorphin inhibits the reaction [AICA ribonucleotide results in decreased expression of IL6 mRNA]		 CTD PMID:24465016 PMID:25108154 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INS-IGF2 INS-IGF2 readthrough multiple interactions ISO AICA ribonucleotide inhibits the reaction [INS1 protein results in increased phosphorylation of TBC1D1 protein]; AICA ribonucleotide inhibits the reaction [INS1 protein results in increased phosphorylation of TBC1D4 protein] CTD PMID:24343960 PMID:26627467 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209 		JBrowse link
G INSR insulin receptor multiple interactions
decreases activity
decreases expression		 EXP 5'-amino-5'-deoxyadenosine inhibits the reaction [AICA ribonucleotide results in decreased activity of INSR promoter]; 5'-amino-5'-deoxyadenosine inhibits the reaction [AICA ribonucleotide results in decreased expression of INSR mRNA]; 5'-amino-5'-deoxyadenosine inhibits the reaction [AICA ribonucleotide results in decreased expression of INSR protein]; Dipyridamole inhibits the reaction [AICA ribonucleotide results in decreased activity of INSR promoter]; Dipyridamole inhibits the reaction [AICA ribonucleotide results in decreased expression of INSR mRNA]; Dipyridamole inhibits the reaction [AICA ribonucleotide results in decreased expression of INSR protein]
AICA ribonucleotide results in decreased expression of INSR mRNA; AICA ribonucleotide results in decreased expression of INSR protein		 CTD PMID:15694368 NCBI chr19:7,112,265...7,294,414
Ensembl chr19:7,112,255...7,294,414 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 affects response to substance ISO KCNJ11 protein affects the susceptibility to AICA ribonucleotide CTD PMID:24498880 NCBI chr11:17,385,248...17,389,346
Ensembl chr11:17,365,172...17,389,331 		JBrowse link
G KLF15 KLF transcription factor 15 decreases expression ISO AICA ribonucleotide results in decreased expression of KLF15 mRNA CTD PMID:24428821 NCBI chr 3:126,288,125...126,357,408
Ensembl chr 3:126,342,635...126,357,408 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 increases activity ISO AICAR increases activity of Map3k7 protein in cardiac muscle cells RGD PMID:17085580 RGD:155791450 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation
decreases phosphorylation		 ISO
EXP		 AICA ribonucleotide inhibits the reaction [[IGF1 protein co-treated with FSHB protein] results in increased phosphorylation of MAPK1 protein]; AICA ribonucleotide inhibits the reaction [IGF1 protein results in increased phosphorylation of MAPK1 protein]
AICA ribonucleotide results in increased phosphorylation of MAPK1 protein
AICA ribonucleotide results in decreased phosphorylation of MAPK1 protein		 CTD PMID:16020477 PMID:28038998 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation
decreases phosphorylation		 ISO
EXP		 AICA ribonucleotide inhibits the reaction [[IGF1 protein co-treated with FSHB protein] results in increased phosphorylation of MAPK3 protein]; AICA ribonucleotide inhibits the reaction [FSHB protein results in increased phosphorylation of MAPK3 protein]; MAPK3 protein affects the reaction [AICA ribonucleotide results in increased uptake of Deoxyglucose]; PTK2B protein affects the reaction [AICA ribonucleotide results in increased activity of MAPK3 protein]
AICA ribonucleotide results in increased phosphorylation of MAPK3 protein
AICA ribonucleotide results in decreased phosphorylation of MAPK3 protein		 CTD PMID:11978788 PMID:16020477 PMID:28038998 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MFN1 mitofusin 1 multiple interactions ISO AICA ribonucleotide inhibits the reaction [Acetaminophen results in decreased expression of MFN1 protein]; AICA ribonucleotide inhibits the reaction [Diclofenac results in decreased expression of MFN1 protein] CTD PMID:27792760 NCBI chr 3:179,347,709...179,394,936
Ensembl chr 3:179,347,709...179,394,936 		JBrowse link
G MFN2 mitofusin 2 multiple interactions ISO AICA ribonucleotide inhibits the reaction [Acetaminophen results in decreased expression of MFN2 protein]; AICA ribonucleotide inhibits the reaction [Diclofenac results in decreased expression of MFN2 protein] CTD PMID:27792760 NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211 		JBrowse link
G MMP13 matrix metallopeptidase 13 multiple interactions EXP AICA ribonucleotide inhibits the reaction [TGFB1 protein results in decreased expression of MMP13 protein] CTD PMID:27688165 NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732 		JBrowse link
G MMP2 matrix metallopeptidase 2 decreases activity EXP AICA ribonucleotide results in decreased activity of MMP2 protein CTD PMID:20590612 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP9 matrix metallopeptidase 9 decreases activity EXP AICA ribonucleotide results in decreased activity of MMP9 protein CTD PMID:20590612 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MPST mercaptopyruvate sulfurtransferase decreases expression ISO AICA ribonucleotide results in decreased expression of MPST mRNA CTD PMID:35577173 NCBI chr22:37,019,742...37,029,815
Ensembl chr22:37,019,635...37,029,821 		JBrowse link
G MTOR mechanistic target of rapamycin kinase decreases activity
decreases phosphorylation
multiple interactions		 EXP
ISO		 AICA ribonucleotide results in decreased activity of MTOR protein
AICA ribonucleotide results in decreased phosphorylation of MTOR protein
AICA ribonucleotide promotes the reaction [4-nonylphenol results in decreased phosphorylation of MTOR protein]
AICA ribonucleotide promotes the reaction [Cadmium results in decreased phosphorylation of MTOR protein]		 CTD PMID:19625624 PMID:21767558 PMID:27363783 PMID:28041982 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 multiple interactions ISO AICA ribonucleotide inhibits the reaction [Cadmium Chloride results in increased expression of NCF1 protein] CTD PMID:21195169 NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315 		JBrowse link
G NCF2 neutrophil cytosolic factor 2 multiple interactions ISO AICA ribonucleotide inhibits the reaction [Cadmium Chloride results in increased expression of NCF2 protein] CTD PMID:21195169 NCBI chr 1:183,555,562...183,601,849
Ensembl chr 1:183,554,461...183,590,905 		JBrowse link
G NCF4 neutrophil cytosolic factor 4 multiple interactions ISO AICA ribonucleotide inhibits the reaction [Cadmium Chloride results in increased expression of NCF4 protein] CTD PMID:21195169 NCBI chr22:36,861,006...36,878,015
Ensembl chr22:36,860,988...36,878,017 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions ISO AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in increased localization of NFKB1 protein] CTD PMID:22025971 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]
AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; dorsomorphin inhibits the reaction [AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]]		 CTD PMID:24465016 PMID:25108154 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 multiple interactions ISO AICA ribonucleotide inhibits the reaction [Palmitic Acid inhibits the reaction [Acetylcholine results in increased phosphorylation of NOS3 protein]] CTD PMID:25108154 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 decreases expression ISO AICA ribonucleotide results in decreased expression of NR0B2 mRNA CTD PMID:24428821 NCBI chr 1:26,911,489...26,913,975
Ensembl chr 1:26,911,489...26,913,975 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 decreases expression ISO AICA ribonucleotide results in decreased expression of NR1H4 mRNA; AICA ribonucleotide results in decreased expression of NR1H4 protein CTD PMID:27090119 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414 		JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 multiple interactions ISO AICA ribonucleotide inhibits the reaction [Phenobarbital results in increased localization of and results in increased activity of NR1I3 protein]; AICA ribonucleotide promotes the reaction [NR1I3 protein results in increased expression of CYP2B10 mRNA]; PRKAA2 protein promotes the reaction [AICA ribonucleotide promotes the reaction [NR1I3 protein results in increased expression of CYP2B10 mRNA]] CTD PMID:20686344 PMID:22815988 NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244 		JBrowse link
G NRF1 nuclear respiratory factor 1 multiple interactions
increases expression		 ISO dorsomorphin inhibits the reaction [AICA ribonucleotide results in increased expression of NRF1 mRNA] CTD PMID:20438809 NCBI chr 7:129,611,720...129,757,076
Ensembl chr 7:129,611,720...129,757,082 		JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase multiple interactions ISO AICA ribonucleotide inhibits the reaction [Acetaminophen results in decreased expression of OPA1 protein]; AICA ribonucleotide inhibits the reaction [Diclofenac results in decreased expression of OPA1 protein] CTD PMID:27792760 NCBI chr 3:193,593,208...193,697,811
Ensembl chr 3:193,593,144...193,697,811 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions ISO AICA ribonucleotide inhibits the reaction [Phenylephrine results in decreased expression of PPARA mRNA]; AICA ribonucleotide inhibits the reaction [Phenylephrine results in decreased expression of PPARA protein] CTD PMID:19699196 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions ISO
EXP		 AICA ribonucleotide inhibits the reaction [Palmitic Acid results in decreased expression of PPARG mRNA]
AICA ribonucleotide inhibits the reaction [TGFB1 protein results in decreased expression of PPARG protein]		 CTD PMID:25108154 PMID:27688165 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha multiple interactions
increases expression
decreases expression		 ISO
EXP		 dorsomorphin inhibits the reaction [AICA ribonucleotide results in increased expression of PPARGC1A mRNA]
AICA ribonucleotide results in decreased expression of PPARGC1A mRNA
AICA ribonucleotide inhibits the reaction [Glucose results in decreased expression of PPARGC1A protein]; dorsomorphin promotes the reaction [AICA ribonucleotide results in decreased expression of PPARGC1A mRNA]
AICA ribonucleotide inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of PPARGC1A protein]		 CTD PMID:20438809 PMID:23090186 PMID:24428821 PMID:25522270 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 increases phosphorylation
multiple interactions
increases expression
increases activity		 ISO
EXP		 AICA ribonucleotide results in increased phosphorylation of PRKAA1 protein
AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of PRKAA1 protein]; dorsomorphin inhibits the reaction [AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of PRKAA1 protein]]; dorsomorphin inhibits the reaction [AICA ribonucleotide results in increased phosphorylation of PRKAA1 protein]
AICA ribonucleotide promotes the reaction [Quercetin results in increased phosphorylation of and results in increased activity of PRKAA1 protein]; AICA ribonucleotide results in increased phosphorylation of and results in increased activity of PRKAA1 protein; PRKAA1 protein affects the reaction [AICA ribonucleotide results in increased expression of CYP4F2 mRNA]; Quercetin promotes the reaction [AICA ribonucleotide results in increased phosphorylation of and results in increased activity of PRKAA1 protein]
AICA ribonucleotide results in increased expression of PRKAA1 protein modified form
[AICA ribonucleotide results in increased phosphorylation of PRKAA1 protein] which results in decreased secretion of Progesterone; AICA ribonucleotide inhibits the reaction [Cadmium Chloride results in decreased phosphorylation of PRKAA1 protein]; AICA ribonucleotide inhibits the reaction [Sodium Chloride, Dietary results in decreased phosphorylation of and results in decreased activity of PRKAA1 protein]; AICA ribonucleotide inhibits the reaction [Sodium Chloride, Dietary results in increased expression of PRKAA1 mRNA]
AICA ribonucleotide results in increased activity of PRKAA1 protein		 CTD PMID:12519745 PMID:16020477 PMID:16873680 PMID:19293639 PMID:20349193 More... NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374 		JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 multiple interactions
increases phosphorylation		 EXP
ISO		 AICA ribonucleotide results in increased phosphorylation of and results in increased activity of PRKAA2 protein; PRKAA2 protein affects the reaction [AICA ribonucleotide results in increased expression of CYP4F2 mRNA]
PRKAA2 protein promotes the reaction [AICA ribonucleotide promotes the reaction [NR1I3 protein results in increased expression of CYP2B10 mRNA]]
AICA ribonucleotide results in increased phosphorylation of PRKAA2 protein
PRKAA2 protein affects the reaction [AICA ribonucleotide inhibits the reaction [AKT1 protein mutant form affects the susceptibility to Glucose deficiency]]; PRKAA2 protein affects the reaction [AICA ribonucleotide results in increased expression of CTNNB1 mRNA]; PRKAA2 protein affects the reaction [AICA ribonucleotide results in increased expression of CTNNB1 protein]		 CTD PMID:15806154 PMID:16873680 PMID:18482975 PMID:21205922 PMID:21454484 More... NCBI chr 1:56,645,314...56,715,335
Ensembl chr 1:56,645,314...56,715,335 		JBrowse link
G PRKCZ protein kinase C zeta multiple interactions
increases activity		 ISO 1-Butanol inhibits the reaction [AICA ribonucleotide results in increased activity of PRKCZ protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [AICA ribonucleotide results in increased activity of PRKCZ protein]; Genistein inhibits the reaction [AICA ribonucleotide results in increased activity of PRKCZ protein]; GRB2 protein affects the reaction [AICA ribonucleotide results in increased activity of PRKCZ protein]; PTK2B protein affects the reaction [AICA ribonucleotide results in increased activity of PRKCZ protein] CTD PMID:11978788 NCBI chr 1:2,048,504...2,185,395
Ensembl chr 1:2,050,411...2,185,395 		JBrowse link
G PTEN phosphatase and tensin homolog increases response to substance EXP PTEN protein results in increased susceptibility to AICA ribonucleotide CTD PMID:19625624 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:22025971 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta multiple interactions ISO AICA ribonucleotide results in increased phosphorylation of and results in increased activity of PTK2B protein; PTK2B protein affects the reaction [AICA ribonucleotide results in increased activity of MAPK3 protein]; PTK2B protein affects the reaction [AICA ribonucleotide results in increased activity of PRKCZ protein] CTD PMID:11978788 NCBI chr 8:27,310,506...27,459,391
Ensembl chr 8:27,311,482...27,459,391 		JBrowse link
G RAC1 Rac family small GTPase 1 multiple interactions ISO AICA ribonucleotide inhibits the reaction [Cadmium Chloride results in increased expression of RAC1 protein] CTD PMID:21195169 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO RAF1 protein affects the reaction [AICA ribonucleotide results in increased uptake of Deoxyglucose] CTD PMID:11978788 NCBI chr 3:12,583,601...12,664,117
Ensembl chr 3:12,582,101...12,664,201 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO AICA ribonucleotide inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of RELA protein]
AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]; dorsomorphin inhibits the reaction [AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]]; Niacinamide inhibits the reaction [AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]]		 CTD PMID:22058332 PMID:25108154 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RPS6 ribosomal protein S6 decreases phosphorylation EXP AICA ribonucleotide results in decreased phosphorylation of RPS6 protein CTD PMID:19625624 NCBI chr 9:19,375,715...19,380,236
Ensembl chr 9:19,375,715...19,380,236 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 multiple interactions
decreases phosphorylation
increases phosphorylation		 ISO AICA ribonucleotide inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein]; naringin inhibits the reaction [AICA ribonucleotide results in increased phosphorylation of RPS6KB1 protein]
AICA ribonucleotide results in decreased phosphorylation of RPS6KB1 protein		 CTD PMID:15342961 PMID:21195169 PMID:28041982 NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574 		JBrowse link
G SIRT1 sirtuin 1 multiple interactions
increases expression		 ISO
EXP		 [Niacinamide results in decreased activity of SIRT1 protein] which results in decreased susceptibility to AICA ribonucleotide
AICA ribonucleotide inhibits the reaction [TGFB1 protein results in decreased expression of SIRT1 protein]
AICA ribonucleotide results in increased expression of SIRT1 protein
AICA ribonucleotide inhibits the reaction [Glucose results in decreased expression of SIRT1 protein]; AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in decreased expression of SIRT1 protein]; AICA ribonucleotide inhibits the reaction [Streptozocin results in decreased activity of SIRT1 protein]; dorsomorphin inhibits the reaction [AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in decreased expression of SIRT1 protein]]; dorsomorphin inhibits the reaction [AICA ribonucleotide results in increased expression of SIRT1 protein]		 CTD PMID:22058332 PMID:23090186 PMID:24465016 PMID:25108154 PMID:27688165 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G SLC10A1 solute carrier family 10 member 1 decreases expression ISO AICA ribonucleotide results in decreased expression of SLC10A1 mRNA CTD PMID:27090119 NCBI chr14:69,775,416...69,797,241
Ensembl chr14:69,775,416...69,797,241 		JBrowse link
G SLC15A1 solute carrier family 15 member 1 decreases activity EXP AICA ribonucleotide results in decreased activity of SLC15A1 protein CTD PMID:22108913 NCBI chr13:98,683,801...98,752,672
Ensembl chr13:98,683,801...98,752,672 		JBrowse link
G SLC2A4 solute carrier family 2 member 4 multiple interactions
increases localization		 ISO 1-Butanol inhibits the reaction [AICA ribonucleotide results in increased localization of SLC2A4 protein]; Genistein inhibits the reaction [AICA ribonucleotide results in increased localization of SLC2A4 protein]; U 0126 inhibits the reaction [AICA ribonucleotide results in increased localization of SLC2A4 protein]; wortmannin inhibits the reaction [AICA ribonucleotide results in increased localization of SLC2A4 protein]
AICA ribonucleotide inhibits the reaction [Palmitates results in decreased expression of SLC2A4 mRNA]		 CTD PMID:11978788 PMID:21802492 NCBI chr17:7,281,718...7,288,257
Ensembl chr17:7,281,718...7,288,257 		JBrowse link
G SLCO1A2 solute carrier organic anion transporter family member 1A2 decreases expression ISO AICA ribonucleotide results in decreased expression of SLCO1A2 mRNA CTD PMID:27090119 NCBI chr12:21,264,600...21,419,634
Ensembl chr12:21,264,600...21,419,594 		JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions
increases expression		 EXP AICA ribonucleotide promotes the reaction [FOXO1 protein results in increased expression of SOD2 mRNA]
AICA ribonucleotide results in increased expression of SOD2 mRNA; AICA ribonucleotide results in increased expression of SOD2 protein		 CTD PMID:25065674 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SQSTM1 sequestosome 1 increases expression
multiple interactions		 EXP AICA ribonucleotide results in increased expression of SQSTM1 protein
[AICA ribonucleotide co-treated with Sirolimus] results in increased expression of SQSTM1 protein; TP53 gene mutant form promotes the reaction [AICA ribonucleotide results in increased expression of SQSTM1 protein]		 CTD PMID:33070465 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G STK11 serine/threonine kinase 11 multiple interactions EXP AICA ribonucleotide inhibits the reaction [TGFB1 protein results in decreased phosphorylation of STK11 protein] CTD PMID:27688165 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431 		JBrowse link
G TBC1D1 TBC1 domain family member 1 multiple interactions ISO AICA ribonucleotide inhibits the reaction [INS1 protein results in increased phosphorylation of TBC1D1 protein] CTD PMID:26627467 NCBI chr 4:37,891,084...38,139,173
Ensembl chr 4:37,891,084...38,139,175 		JBrowse link
G TBC1D4 TBC1 domain family member 4 multiple interactions ISO AICA ribonucleotide inhibits the reaction [INS1 protein results in increased phosphorylation of TBC1D4 protein] CTD PMID:24343960 PMID:26627467 NCBI chr13:75,283,503...75,482,169
Ensembl chr13:75,283,503...75,482,169 		JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions EXP AICA ribonucleotide inhibits the reaction [TGFB1 protein results in decreased expression of MMP13 protein]; AICA ribonucleotide inhibits the reaction [TGFB1 protein results in decreased expression of PPARG protein]; AICA ribonucleotide inhibits the reaction [TGFB1 protein results in decreased expression of SIRT1 protein]; AICA ribonucleotide inhibits the reaction [TGFB1 protein results in decreased phosphorylation of STK11 protein]; AICA ribonucleotide inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; AICA ribonucleotide inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]; AICA ribonucleotide inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 protein] CTD PMID:27688165 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 multiple interactions EXP AICA ribonucleotide inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 protein] CTD PMID:27688165 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO
EXP		 AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
AICA ribonucleotide inhibits the reaction [TNF protein promotes the reaction [Oxygen deficiency results in increased expression of GPR68 mRNA]]; AICA ribonucleotide inhibits the reaction [TNF protein results in increased expression of GPR68 mRNA]
AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]		 CTD PMID:22025971 PMID:25108154 PMID:28174749 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A multiple interactions ISO AICA ribonucleotide inhibits the reaction [Lipopolysaccharides results in increased expression of TNFRSF1A protein] CTD PMID:22025971 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TP53 tumor protein p53 multiple interactions
increases phosphorylation		 EXP [Resveratrol co-treated with AICA ribonucleotide] inhibits the reaction [Glucose results in increased expression of TP53 protein]; AICA ribonucleotide inhibits the reaction [TP53 gene mutant form results in increased expression of CPT1A protein]; AICA ribonucleotide promotes the reaction [TP53 gene mutant form results in increased phosphorylation of ULK1 protein]; TP53 gene mutant form promotes the reaction [AICA ribonucleotide results in increased expression of SQSTM1 protein]; TP53 gene mutant form promotes the reaction [AICA ribonucleotide results in increased phosphorylation of ULK1 protein]
AICA ribonucleotide results in increased phosphorylation of TP53 protein		 CTD PMID:26188290 PMID:33070465 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538 		JBrowse link
G TXNIP thioredoxin interacting protein multiple interactions ISO AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of TXNIP protein] CTD PMID:29031535 NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579 		JBrowse link
G UCP2 uncoupling protein 2 multiple interactions ISO AICA ribonucleotide inhibits the reaction [Indican results in decreased expression of UCP2 mRNA] CTD PMID:25703824 NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,672...73,982,843 		JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 multiple interactions EXP AICA ribonucleotide promotes the reaction [TP53 gene mutant form results in increased phosphorylation of ULK1 protein]; AICA ribonucleotide results in increased expression of and results in increased phosphorylation of ULK1 protein; TP53 gene mutant form promotes the reaction [AICA ribonucleotide results in increased phosphorylation of ULK1 protein] CTD PMID:33070465 NCBI chr12:131,894,622...131,923,150
Ensembl chr12:131,894,622...131,923,150 		JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions EXP AICA ribonucleotide inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased secretion of VEGFA protein] CTD PMID:30724446 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G XPO1 exportin 1 multiple interactions EXP AICA ribonucleotide promotes the reaction [ABL1 protein mutant form binds to XPO1 protein]; AICA ribonucleotide promotes the reaction [XPO1 protein binds to BECN1 protein]; AICA ribonucleotide promotes the reaction [XPO1 protein binds to YWHAQ protein] CTD PMID:33070465 NCBI chr 2:61,477,849...61,538,612
Ensembl chr 2:61,476,032...61,538,741 		JBrowse link
G YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta multiple interactions EXP AICA ribonucleotide promotes the reaction [ABL1 protein mutant form binds to YWHAQ protein]; AICA ribonucleotide promotes the reaction [XPO1 protein binds to YWHAQ protein] CTD PMID:33070465 NCBI chr 2:9,583,967...9,630,997
Ensembl chr 2:9,583,967...9,630,997 		JBrowse link
AMP-PNP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor multiple interactions ISO Adenylyl Imidodiphosphate affects the folding of [Tetrachlorodibenzodioxin binds to AHR protein] CTD PMID:1848756 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G CFTR CF transmembrane conductance regulator affects activity EXP Adenylyl Imidodiphosphate affects the activity of CFTR protein CTD PMID:15657297 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971 		JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 affects binding EXP Adenylyl Imidodiphosphate binds to CSNK2A1 protein CTD PMID:34344863 NCBI chr20:472,498...543,790
Ensembl chr20:472,498...543,835 		JBrowse link
G PTGDR prostaglandin D2 receptor multiple interactions EXP Adenylyl Imidodiphosphate inhibits the reaction [Prostaglandin D2 binds to PTGDR protein] CTD PMID:9579725 NCBI chr14:52,267,698...52,280,914
Ensembl chr14:52,267,698...52,276,724 		JBrowse link
arachidonoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPARA peroxisome proliferator activated receptor alpha multiple interactions EXP arachidonyl-coenzyme A binds to and results in increased activity of PPARA protein CTD PMID:11139385 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
ATP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA8 ATP binding cassette subfamily A member 8 multiple interactions EXP Adenosine Triphosphate affects the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide] CTD PMID:12379217 NCBI chr17:68,867,289...68,955,392
Ensembl chr17:68,867,289...68,955,392 		JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions
affects binding
increases hydrolysis		 EXP
ISO		 [Cobalt results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate; [Magnesium results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate; [Manganese results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate; ABCB1 protein binds to and results in increased hydrolysis of Adenosine Triphosphate; aurapten promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]; crizotinib promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]; Disulfiram affects the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]; lapatinib promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]; nobiletin promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]
Adenosine Triphosphate binds to ABCB1 protein
[Rifampin metabolite results in decreased activity of ABCB1A protein] which results in decreased abundance of Adenosine Triphosphate		 CTD PMID:2900677 PMID:14978246 PMID:18829547 PMID:18955043 PMID:22233293 More... NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCB11 ATP binding cassette subfamily B member 11 multiple interactions EXP
ISO		 Adenosine Triphosphate promotes the reaction [ABCB11 protein results in increased uptake of fexofenadine] CTD PMID:18245269 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) multiple interactions
affects activity
increases hydrolysis
affects binding		 EXP
ISO		 [Adenosine Triphosphate affects the activity of ABCC1 protein] which results in increased transport of Acetaminophen metabolite; ABCC1 protein binds to and results in increased degradation of Adenosine Triphosphate; ABCC1 protein binds to and results in increased hydrolysis of Adenosine Triphosphate; ABCC1 protein mutant form binds to and results in increased hydrolysis of Adenosine Triphosphate; Adenosine Triphosphate binds to and affects the folding of ABCC1 protein; Adenosine Triphosphate promotes the reaction [ABCC1 protein affects the transport of Bilirubin]; Adenosine Triphosphate promotes the reaction [ABCC1 protein affects the transport of estradiol-17 beta-glucuronide]; Adenosine Triphosphate promotes the reaction [ABCC1 protein affects the transport of Leukotriene C4]; daidzein promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Disulfiram affects the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; hesperetin promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; naringenin promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; nobiletin promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Quercetin affects the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Resveratrol promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Silymarin inhibits the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]
Daunorubicin promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Vanadates inhibits the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]
Adenosine Triphosphate binds to ABCC1 protein		 CTD PMID:10856430 PMID:11278000 PMID:14978246 PMID:15245331 PMID:15355964 More... NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 multiple interactions
affects activity
affects metabolic processing		 ISO
EXP		 Adenosine Triphosphate promotes the reaction [ABCC2 protein results in increased secretion of Fluo-3]; Adenosine Triphosphate promotes the reaction [ABCC2 protein results in increased transport of temocaprilat]
Adenosine Triphosphate affects the activity of ABCC2 protein
[Adenosine Triphosphate affects the activity of ABCC2 protein] which results in increased transport of Acetaminophen metabolite; [Adenosine Triphosphate co-treated with ABCC2 protein] results in increased uptake of estradiol-17 beta-glucuronide; Adenosine Triphosphate affects the reaction [ABCC2 protein results in increased transport of Mercury]; verlukast inhibits the reaction [[Adenosine Triphosphate co-treated with ABCC2 protein] results in increased uptake of estradiol-17 beta-glucuronide]
ABCC2 protein affects the metabolism of Adenosine Triphosphate
Adenosine Triphosphate promotes the reaction [ABCC2 protein results in increased transport of S-1,2-dichlorovinyl-N-acetylcysteine]		 CTD PMID:9067317 PMID:9794919 PMID:20060011 PMID:22027652 PMID:24039982 More... NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 multiple interactions ISO Adenosine Triphosphate promotes the reaction [ABCC3 protein affects the transport of fexofenadine] CTD PMID:18245269 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253 		JBrowse link
G ABCC4 ATP binding cassette subfamily C member 4 (PEL blood group) multiple interactions
affects activity
increases hydrolysis		 EXP [Adenosine Triphosphate affects the activity of ABCC4 protein] which results in increased transport of Acetaminophen metabolite; ABCC4 protein binds to and results in increased hydrolysis of Adenosine Triphosphate; daidzein promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; Disulfiram inhibits the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; hesperetin promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; naringenin promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; Quercetin affects the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; Quercetin inhibits the reaction [Alprostadil promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]]; Resveratrol promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; Silymarin inhibits the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; Silymarin inhibits the reaction [Alprostadil promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]] CTD PMID:14978246 PMID:16156793 PMID:32472168 NCBI chr13:95,019,835...95,301,451
Ensembl chr13:95,019,835...95,301,475 		JBrowse link
G ABCC6 ATP binding cassette subfamily C member 6 affects binding EXP Adenosine Triphosphate binds to ABCC6 protein CTD PMID:11880368 NCBI chr16:16,149,565...16,223,494
Ensembl chr16:16,149,565...16,223,522 		JBrowse link
G ABCC8 ATP binding cassette subfamily C member 8 multiple interactions ISO Adenosine Triphosphate deficiency inhibits the reaction [Estradiol inhibits the reaction [Glyburide binds to ABCC8 protein]] CTD PMID:19095654 NCBI chr11:17,392,498...17,476,845
Ensembl chr11:17,392,498...17,476,894 		JBrowse link
G ABCC9 ATP binding cassette subfamily C member 9 multiple interactions ISO Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]; Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]; Creatine metabolite inhibits the reaction [Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]]
Adenosine Triphosphate results in decreased activity of [KCNJ8 protein binds to ABCC9 protein]		 CTD PMID:11390963 PMID:28842488 NCBI chr12:21,797,389...21,941,426
Ensembl chr12:21,797,389...21,942,543 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) increases hydrolysis
multiple interactions		 EXP ABCG2 protein results in increased hydrolysis of Adenosine Triphosphate
[Adenosine Triphosphate co-treated with ABCG2 protein] results in increased uptake of estrone sulfate; Lapatinib promotes the reaction [ABCG2 protein results in increased hydrolysis of Adenosine Triphosphate]; Sulfasalazine inhibits the reaction [[Adenosine Triphosphate co-treated with ABCG2 protein] results in increased uptake of estrone sulfate]		 CTD PMID:18829547 PMID:32003934 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628 		JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase multiple interactions
increases chemical synthesis		 EXP [ABL1 protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein; sorafenib inhibits the reaction [[ABL1 protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein]
ABL1 protein mutant form results in increased chemical synthesis of Adenosine Triphosphate		 CTD PMID:19366808 PMID:33070465 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,043...130,887,675 		JBrowse link
G ACSL5 acyl-CoA synthetase long chain family member 5 multiple interactions EXP [ACSL5 protein affects the susceptibility to Palmitic Acid] which affects the abundance of Adenosine Triphosphate CTD PMID:32347412 NCBI chr10:112,374,116...112,428,376
Ensembl chr10:112,374,116...112,428,379 		JBrowse link
G ACTA2 actin alpha 2, smooth muscle multiple interactions EXP 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of ACTA2 mRNA]; 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of ACTA2 protein]; [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of ACTA2 mRNA; [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of ACTA2 protein; Adenosine Triphosphate promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of Biological Factors] which results in increased expression of ACTA2 mRNA]; Adenosine Triphosphate promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of Biological Factors] which results in increased expression of ACTA2 protein]; Adenosine Triphosphate promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ACTA2 mRNA]; Adenosine Triphosphate promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ACTA2 protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of ACTA2 mRNA]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of ACTA2 protein]; L 709049 inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of ACTA2 mRNA]; L 709049 inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of ACTA2 protein] CTD PMID:32721574 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,935,074...88,991,339 		JBrowse link
G ADCYAP1 adenylate cyclase activating polypeptide 1 increases secretion ISO ADCYAP1 protein results in increased secretion of Adenosine Triphosphate CTD PMID:18563302 NCBI chr18:904,411...912,172
Ensembl chr18:904,871...912,172 		JBrowse link
G AGTR1 angiotensin II receptor type 1 multiple interactions
decreases expression		 ISO Adenosine Triphosphate results in decreased expression of and results in decreased activity of AGTR1A protein; ARRB2 protein affects the reaction [Adenosine Triphosphate results in decreased activity of AGTR1A protein]; CABIN1 protein inhibits the reaction [Adenosine Triphosphate results in decreased expression of and results in decreased activity of AGTR1A protein]; Cyclosporine inhibits the reaction [Adenosine Triphosphate results in decreased expression of AGTR1A mRNA]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Adenosine Triphosphate results in decreased expression of AGTR1A mRNA]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Adenosine Triphosphate results in decreased expression of AGTR1A protein] CTD PMID:21464294 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G AHR aryl hydrocarbon receptor multiple interactions ISO Adenosine Triphosphate affects the folding of [Tetrachlorodibenzodioxin binds to AHR protein] CTD PMID:1848756 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 decreases activity
multiple interactions		 EXP Adenosine Triphosphate results in decreased activity of AKT1 protein
Alcohols inhibits the reaction [Adenosine Triphosphate results in decreased activity of AKT1 protein]		 CTD PMID:24300283 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G ALDH5A1 aldehyde dehydrogenase 5 family member A1 increases abundance ISO ALDH5A1 gene mutant form results in increased abundance of Adenosine Triphosphate CTD PMID:29031482 NCBI chr 6:24,494,969...24,537,207
Ensembl chr 6:24,494,867...24,537,207 		JBrowse link
G ALK ALK receptor tyrosine kinase affects binding
multiple interactions		 EXP ALK protein binds to Adenosine Triphosphate
[ALK protein mutant form promotes the reaction [ALK protein binds to Adenosine Triphosphate]] which results in decreased susceptibility to crizotinib; ALK protein mutant form promotes the reaction [ALK protein binds to Adenosine Triphosphate]		 CTD PMID:22072639 NCBI chr 2:29,192,774...29,921,586
Ensembl chr 2:29,192,774...29,921,586 		JBrowse link
G ALPL alkaline phosphatase, biomineralization associated increases response to substance
multiple interactions		 ISO ALPL gene mutant form results in increased susceptibility to Adenosine Triphosphate
ALPL gene mutant form promotes the reaction [Adenosine Triphosphate results in increased expression of FOS mRNA]		 CTD PMID:27466191 NCBI chr 1:21,508,984...21,578,410
Ensembl chr 1:21,509,397...21,578,410 		JBrowse link
G ANXA1 annexin A1 multiple interactions ISO [Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein; arsenite affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]; Cadmium affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]; chromium hexavalent ion affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]; Lead affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein] CTD PMID:20655937 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393 		JBrowse link
G APP amyloid beta precursor protein increases secretion
multiple interactions		 EXP Adenosine Triphosphate results in increased secretion of APP protein modified form
Adenosine Triphosphate inhibits the reaction [Hydrogen Peroxide results in decreased secretion of APP protein modified form]; Adenosine Triphosphate inhibits the reaction [Rotenone results in decreased secretion of APP protein modified form]; Rotenone inhibits the reaction [Adenosine Triphosphate results in increased secretion of APP protein modified form]; Sodium Azide inhibits the reaction [Adenosine Triphosphate results in increased secretion of APP protein modified form]		 CTD PMID:22906069 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G ARRB2 arrestin beta 2 multiple interactions ISO Adenosine Triphosphate promotes the reaction [RELA protein binds to ARRB2 protein]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to ARRB2 protein]]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to NFKBIA protein]]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to NOS2 protein]]; ARRB2 protein affects the reaction [Adenosine Triphosphate results in decreased activity of AGTR1A protein] CTD PMID:21464294 NCBI chr17:4,710,632...4,721,497
Ensembl chr17:4,710,596...4,721,499 		JBrowse link
G ASIC1 acid sensing ion channel subunit 1 multiple interactions ISO [Acids binds to and affects the activity of ASIC1 protein] which results in increased secretion of Adenosine Triphosphate CTD PMID:19860742 NCBI chr12:50,057,596...50,083,622
Ensembl chr12:50,057,548...50,083,611 		JBrowse link
G ASIC2 acid sensing ion channel subunit 2 multiple interactions ISO [Acids binds to and affects the activity of ASIC2 protein] which results in increased secretion of Adenosine Triphosphate CTD PMID:19860742 NCBI chr17:33,013,087...34,156,768
Ensembl chr17:33,013,087...34,174,964 		JBrowse link
G ASIC3 acid sensing ion channel subunit 3 multiple interactions ISO [Acids binds to and affects the activity of ASIC3 protein] which results in increased secretion of Adenosine Triphosphate CTD PMID:19860742 NCBI chr 7:151,048,292...151,052,756
Ensembl chr 7:151,048,292...151,052,756 		JBrowse link
G ATP7A ATPase copper transporting alpha multiple interactions EXP [Copper co-treated with Adenosine Triphosphate] results in increased phosphorylation of ATP7A protein CTD PMID:20964302 NCBI chr  X:77,910,693...78,050,395
Ensembl chr  X:77,910,690...78,050,395 		JBrowse link
G ATP7B ATPase copper transporting beta multiple interactions
increases phosphorylation		 EXP [Copper co-treated with Adenosine Triphosphate] results in increased phosphorylation of ATP7B protein
Adenosine Triphosphate results in increased phosphorylation of ATP7B protein		 CTD PMID:19405516 PMID:20964302 NCBI chr13:51,932,669...52,012,132
Ensembl chr13:51,930,436...52,012,125 		JBrowse link
G ATP8B1 ATPase phospholipid transporting 8B1 increases hydrolysis ISO ATP8B1 protein results in increased hydrolysis of Adenosine Triphosphate CTD PMID:11584374 NCBI chr18:57,646,426...57,803,315
Ensembl chr18:57,646,426...57,803,315 		JBrowse link
G AVP arginine vasopressin multiple interactions
increases secretion		 ISO Adenosine Triphosphate promotes the reaction [Phenylephrine results in increased secretion of AVP protein]; bisindolylmaleimide I inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein]; Dactinomycin inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased secretion of AVP protein] CTD PMID:11102496 NCBI chr20:3,082,556...3,084,724
Ensembl chr20:3,082,556...3,084,724 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions EXP [Adenosine Triphosphate binds to P2RY11 protein] which results in decreased expression of BCL2 protein CTD PMID:21503959 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCR BCR activator of RhoGEF and GTPase multiple interactions EXP [BCR protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein; sorafenib inhibits the reaction [[BCR protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein] CTD PMID:19366808 NCBI chr22:23,180,509...23,318,037
Ensembl chr22:23,179,704...23,318,037 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 increases abundance EXP BIRC5 protein results in increased abundance of Adenosine Triphosphate CTD PMID:32497533 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636 		JBrowse link
G CABIN1 calcineurin binding protein 1 multiple interactions ISO CABIN1 protein inhibits the reaction [Adenosine Triphosphate results in decreased expression of and results in decreased activity of AGTR1A protein] CTD PMID:21464294 NCBI chr22:24,011,304...24,178,628
Ensembl chr22:24,011,192...24,178,628 		JBrowse link
G CALCA calcitonin related polypeptide alpha increases secretion
multiple interactions		 ISO Adenosine Triphosphate results in increased secretion of CALCA protein
Adenosine Triphosphate promotes the reaction [Protons results in increased secretion of CALCA protein]; Flurbiprofen inhibits the reaction [Adenosine Triphosphate promotes the reaction [Protons results in increased secretion of CALCA protein]]; Suramin inhibits the reaction [Adenosine Triphosphate promotes the reaction [Protons results in increased secretion of CALCA protein]]		 CTD PMID:12044622 NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354 		JBrowse link
G CASP1 caspase 1 increases activity
multiple interactions		 ISO
EXP		 Adenosine Triphosphate results in increased activity of CASP1 mRNA; Adenosine Triphosphate results in increased activity of CASP1 protein
[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]
[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP1 protein; [Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of and results in increased cleavage of CASP1 protein; [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of CASP1 mRNA; [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased secretion of and results in increased activity of CASP1 protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein modified form; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased cleavage of CASP1 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein; Acetylcysteine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP1 protein]; fraxinellone inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein]; HK1 protein affects the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of CASP1 protein]; HK1 protein affects the reaction [hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of CASP1 protein]]; hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of and results in increased cleavage of CASP1 protein]; KN 62 inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]; Luteolin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]; mitochondrial uncoupler BAM15 inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP1 protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein modified form]; Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP1 protein]; Resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of CASP1 mRNA]; Resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased secretion of and results in increased activity of CASP1 protein]; ubiquinone-O inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]
[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased cleavage of CASP1 protein; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of CASP1 mRNA; [Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of CASP1 protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] promotes the reaction [PYCARD protein binds to CASP1 protein]; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein modified form; [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to CASP1 protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [PML protein binds to CASP1 protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of and results in increased secretion of CASP1 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein; [Niclosamide co-treated with Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CASP1 protein; Adenosine Triphosphate promotes the reaction [[CSTB gene mutant form results in increased susceptibility to lipopolysaccharide, E coli O55-B5] which results in increased cleavage of CASP1 protein]; Arsenic Trioxide inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein]; Chlorquinaldol inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of and results in increased secretion of CASP1 protein]; lonidamine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] promotes the reaction [PYCARD protein binds to CASP1 protein]]; lonidamine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein modified form]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to CASP1 protein]]; PYCARD protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased cleavage of CASP1 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of CASP1 mRNA]		 CTD PMID:18604214 PMID:19130485 PMID:21832250 PMID:23430110 PMID:24149798 More... NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CASP3 caspase 3 increases expression
multiple interactions		 EXP Adenosine Triphosphate results in increased expression of CASP3
Adenosine Triphosphate inhibits the reaction [chromium hexavalent ion results in increased activity of CASP3 protein]; Suramin inhibits the reaction [Adenosine Triphosphate results in increased expression of CASP3]		 CTD PMID:19448140 PMID:24732427 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP4 caspase 4 multiple interactions EXP
ISO		 [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of CASP4 mRNA; [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased secretion of and results in increased activity of CASP4 protein; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of CASP4 mRNA]; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased secretion of and results in increased activity of CASP4 protein]
Adenosine Triphosphate promotes the reaction [[CSTB gene mutant form results in increased susceptibility to lipopolysaccharide, E coli O55-B5] which results in increased cleavage of CASP4 protein]		 CTD PMID:24149798 PMID:25288807 NCBI chr11:104,942,866...104,968,574
Ensembl chr11:104,942,866...104,969,366 		JBrowse link
G CAT catalase increases expression EXP Adenosine Triphosphate results in increased expression of CAT mRNA CTD PMID:22129738 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 increases secretion
multiple interactions		 ISO Adenosine Triphosphate results in increased secretion of CCL3 protein
azetidine inhibits the reaction [Adenosine Triphosphate results in increased secretion of CCL3 protein]		 CTD PMID:26522449 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G CFTR CF transmembrane conductance regulator multiple interactions EXP 3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [Adenosine Triphosphate promotes the reaction [CFTR protein results in increased export of Chlorides]]; [Phosphatidylinositol 4,5-Diphosphate co-treated with Adenosine Triphosphate] results in increased activity of CFTR protein; Adenosine Triphosphate affects the reaction [Curcumin results in increased activity of CFTR protein mutant form]; Adenosine Triphosphate binds to and results in increased activity of CFTR protein; Adenosine Triphosphate promotes the reaction [CFTR protein results in increased export of Chlorides] CTD PMID:14710196 PMID:15623556 PMID:17178710 PMID:20675434 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971 		JBrowse link
G CHORDC1 cysteine and histidine rich domain containing 1 multiple interactions EXP
ISO		 Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to PPP5C protein]; Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to SUGT1 protein]
Adenosine Triphosphate binds to and affects the folding of CHORDC1 protein; Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to CHORDC1 protein]; Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to HSP90AA1 protein]; Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to CHORDC1 protein]		 CTD PMID:23184943 NCBI chr11:90,200,429...90,223,049
Ensembl chr11:90,200,429...90,223,077 		JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions EXP 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of COL1A1 mRNA]; 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of COL1A1 protein]; [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of COL1A1 mRNA; [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of COL1A1 protein; Adenosine Triphosphate promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of Biological Factors] which results in increased expression of COL1A1 mRNA]; Adenosine Triphosphate promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of Biological Factors] which results in increased expression of COL1A1 protein]; Adenosine Triphosphate promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of COL1A1 mRNA]; Adenosine Triphosphate promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of COL1A1 protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of COL1A1 mRNA]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of COL1A1 protein]; L 709049 inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of COL1A1 mRNA]; L 709049 inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of COL1A1 protein] CTD PMID:32721574 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632 		JBrowse link
G COMT catechol-O-methyltransferase multiple interactions EXP [Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased activity of COMT protein] which results in decreased abundance of Adenosine Triphosphate; [tolcapone results in decreased activity of COMT protein] which results in decreased abundance of Adenosine Triphosphate CTD PMID:14975680 NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975 		JBrowse link
G CPT2 carnitine palmitoyltransferase 2 multiple interactions EXP [Bezafibrate results in increased activity of CPT2 protein] which results in increased abundance of Adenosine Triphosphate; Carnitine promotes the reaction [[Bezafibrate results in increased activity of CPT2 protein] which results in increased abundance of Adenosine Triphosphate] CTD PMID:21816645 NCBI chr 1:53,196,824...53,214,197
Ensembl chr 1:53,196,792...53,214,197 		JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein multiple interactions EXP [ABL1 protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein; [BCR protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein; sorafenib inhibits the reaction [[ABL1 protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein]; sorafenib inhibits the reaction [[BCR protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein] CTD PMID:19366808 NCBI chr22:20,917,407...20,953,747
Ensembl chr22:20,917,407...20,953,747 		JBrowse link
G CSF2 colony stimulating factor 2 multiple interactions EXP [CSF2 protein affects the susceptibility to stearic acid] which affects the abundance of Adenosine Triphosphate CTD PMID:32347412 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 multiple interactions
affects binding		 EXP silmitasertib inhibits the reaction [Adenosine Triphosphate binds to [CSNK2A1 protein binds to CSNK2A1 protein binds to CSNK2B protein binds to CSNK2B protein]] CTD PMID:21174434 NCBI chr20:472,498...543,790
Ensembl chr20:472,498...543,835 		JBrowse link
G CSNK2B casein kinase 2 beta multiple interactions
affects binding		 EXP silmitasertib inhibits the reaction [Adenosine Triphosphate binds to [CSNK2A1 protein binds to CSNK2A1 protein binds to CSNK2B protein binds to CSNK2B protein]] CTD PMID:21174434 NCBI chr 6:31,666,080...31,670,067
Ensembl chr 6:31,665,227...31,670,343 		JBrowse link
G CSTB cystatin B multiple interactions ISO Adenosine Triphosphate promotes the reaction [[CSTB gene mutant form results in increased susceptibility to lipopolysaccharide, E coli O55-B5] which results in increased cleavage of CASP1 protein]; Adenosine Triphosphate promotes the reaction [[CSTB gene mutant form results in increased susceptibility to lipopolysaccharide, E coli O55-B5] which results in increased cleavage of CASP4 protein] CTD PMID:25288807 NCBI chr21:43,773,950...43,776,308
Ensembl chr21:43,772,511...43,776,330 		JBrowse link
G CTSB cathepsin B increases activity
multiple interactions		 ISO Adenosine Triphosphate results in increased activity of CTSB protein
azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased expression of CTSB protein]		 CTD PMID:26522449 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 increases secretion
multiple interactions		 ISO Adenosine Triphosphate results in increased secretion of CXCL2 protein
azetidine inhibits the reaction [Adenosine Triphosphate results in increased secretion of CXCL2 protein]		 CTD PMID:26522449 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G DMD dystrophin increases secretion
multiple interactions		 ISO DMD gene mutant form results in increased secretion of Adenosine Triphosphate
Nifedipine inhibits the reaction [DMD gene mutant form results in increased secretion of Adenosine Triphosphate]		 CTD PMID:24349043 NCBI chr  X:31,119,222...33,339,388
Ensembl chr  X:31,097,677...33,339,609 		JBrowse link
G DUSP1 dual specificity phosphatase 1 multiple interactions EXP Adenosine Triphosphate inhibits the reaction [Cesium-137 results in increased expression of DUSP1 protein]; AZ10606120 inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in decreased expression of DUSP1 protein]] CTD PMID:32941855 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195 		JBrowse link
G DUSP6 dual specificity phosphatase 6 multiple interactions EXP Adenosine Triphosphate inhibits the reaction [Cesium-137 results in increased expression of DUSP6 protein]; AZ10606120 inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in decreased expression of DUSP6 protein]] CTD PMID:32941855 NCBI chr12:89,347,235...89,352,501
Ensembl chr12:89,347,235...89,352,501 		JBrowse link
G EGFR epidermal growth factor receptor multiple interactions
increases phosphorylation		 EXP sodium arsenite promotes the reaction [Adenosine Triphosphate results in increased phosphorylation of EGFR protein] CTD PMID:26104857 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EGR1 early growth response 1 multiple interactions
increases expression		 ISO Iodoacetates inhibits the reaction [Adenosine Triphosphate results in increased expression of EGR1 mRNA]; Potassium Cyanide inhibits the reaction [Adenosine Triphosphate results in increased expression of EGR1 mRNA]; Sodium Azide inhibits the reaction [Adenosine Triphosphate results in increased expression of EGR1 mRNA] CTD PMID:10723097 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303 		JBrowse link
G ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 multiple interactions EXP Adenosine Triphosphate promotes the reaction [Toluene 2,4-Diisocyanate results in increased expression of ENPP2 protein] CTD PMID:26072274 NCBI chr 8:119,557,086...119,673,390
Ensembl chr 8:119,557,086...119,673,453 		JBrowse link
G ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 decreases activity EXP Adenosine Triphosphate results in decreased activity of ENPP7 protein CTD PMID:12885774 NCBI chr17:79,730,943...79,742,219
Ensembl chr17:79,730,943...79,742,219 		JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor decreases abundance
multiple interactions		 ISO ERCC6 gene mutant form results in decreased abundance of Adenosine Triphosphate
nicotinamide-beta-riboside inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Adenosine Triphosphate]		 CTD PMID:25440059 NCBI chr10:49,434,881...49,539,538
Ensembl chr10:49,454,168...49,539,538 		JBrowse link
G F2 coagulation factor II, thrombin multiple interactions
increases transport
increases abundance
increases secretion		 EXP
ISO		 2,4,3',5'-tetramethoxystilbene inhibits the reaction [F2 protein results in increased secretion of Adenosine Triphosphate]; [RWJ-56110 co-treated with 2,4,3',5'-tetramethoxystilbene] inhibits the reaction [F2 protein results in increased secretion of Adenosine Triphosphate]; calmidazolium affects the reaction [F2 protein results in increased secretion of Adenosine Triphosphate]; Fendiline affects the reaction [F2 protein results in increased secretion of Adenosine Triphosphate]; Quercetin inhibits the reaction [F2 protein results in increased abundance of Adenosine Triphosphate]; Resveratrol inhibits the reaction [F2 protein results in increased abundance of Adenosine Triphosphate]
STXBP2 protein affects the reaction [F2 protein results in increased transport of Adenosine Triphosphate]		 CTD PMID:2030746 PMID:15342215 PMID:30696774 PMID:35288162 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506 		JBrowse link
G FAM66C family with sequence similarity 66 member C increases abundance
multiple interactions		 EXP FAM66C mRNA results in increased abundance of Adenosine Triphosphate
[[FAM66C mRNA binds to and results in decreased expression of MIR23 mRNA] which results in increased expression of KCND2 protein] which results in increased abundance of Adenosine Triphosphate		 CTD PMID:34418280 NCBI chr12:8,180,209...8,201,000
Ensembl chr12:8,180,207...8,216,151 		JBrowse link
G FASN fatty acid synthase multiple interactions
decreases abundance		 EXP FASN protein promotes the reaction [rosiglitazone promotes the reaction [PPARG protein results in decreased abundance of Adenosine Triphosphate]]; Protein Kinase Inhibitors inhibits the reaction [FASN protein results in decreased abundance of Adenosine Triphosphate] CTD PMID:26670611 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294 		JBrowse link
G FBP1 fructose-bisphosphatase 1 multiple interactions ISO [Enzyme Inhibitors results in decreased activity of FBP1 protein] which results in decreased abundance of Adenosine Triphosphate CTD PMID:31974165 NCBI chr 9:94,603,133...94,640,263
Ensembl chr 9:94,603,133...94,640,249 		JBrowse link
G FBXO3 F-box protein 3 multiple interactions ISO FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]]; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein]]; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein]]; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]]; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]]; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein]]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein] CTD PMID:35962723 NCBI chr11:33,740,944...33,774,520
Ensembl chr11:33,740,939...33,774,543 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions		 ISO Adenosine Triphosphate results in increased expression of FOS mRNA
ALPL gene mutant form promotes the reaction [Adenosine Triphosphate results in increased expression of FOS mRNA]
[Phenylephrine co-treated with Adenosine Triphosphate] results in increased expression of FOS mRNA; Glucose affects the reaction [Adenosine Triphosphate results in increased expression of FOS mRNA]; Iodoacetates inhibits the reaction [Adenosine Triphosphate results in increased expression of FOS mRNA]; Potassium Cyanide inhibits the reaction [Adenosine Triphosphate results in increased expression of FOS mRNA]; Sodium Azide inhibits the reaction [Adenosine Triphosphate results in increased expression of FOS mRNA]		 CTD PMID:10723097 PMID:19463813 PMID:27466191 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G FSCN1 fascin actin-bundling protein 1 multiple interactions
increases expression		 EXP
ISO		 Niclosamide inhibits the reaction [Adenosine Triphosphate results in increased expression of FSCN1 mRNA] CTD PMID:29733962 NCBI chr 7:5,592,816...5,606,655
Ensembl chr 7:5,592,816...5,606,655 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase multiple interactions EXP Adenosine Triphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog] CTD PMID:15788719 NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374 		JBrowse link
G GH1 growth hormone 1 increases secretion
multiple interactions		 EXP
ISO		 Adenosine Triphosphate results in increased secretion of GH1 protein
NCS1 protein promotes the reaction [Adenosine Triphosphate results in increased secretion of GH1 protein]; oxophenylarsine inhibits the reaction [NCS1 protein promotes the reaction [Adenosine Triphosphate results in increased secretion of GH1 protein]]
oxophenylarsine inhibits the reaction [Adenosine Triphosphate results in increased secretion of GH1 protein]; Phosphatidylinositol 4,5-Diphosphate affects the reaction [Adenosine Triphosphate results in increased secretion of GH1 protein]		 CTD PMID:12471042 NCBI chr17:63,917,203...63,918,839
Ensembl chr17:63,917,200...63,918,839 		JBrowse link
G GJA1 gap junction protein alpha 1 increases export EXP GJA1 protein mutant form results in increased export of Adenosine Triphosphate; GJA1 protein results in increased export of Adenosine Triphosphate CTD PMID:17687502 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727 		JBrowse link
G GSDMD gasdermin D multiple interactions EXP
ISO		 [Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased cleavage of GSDMD protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of GSDMD protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein]; HK1 protein affects the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased cleavage of GSDMD protein]; HK1 protein affects the reaction [hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased cleavage of GSDMD protein]]; hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased cleavage of GSDMD protein]; Luteolin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of GSDMD protein]
[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein]]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein]
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased cleavage of GSDMD protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased cleavage of GSDMD protein; Hirudins inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased cleavage of GSDMD protein]; lonidamine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased cleavage of GSDMD protein]		 CTD PMID:33851234 PMID:34212273 PMID:34217685 PMID:35962723 PMID:36577999 More... NCBI chr 8:143,553,387...143,563,062
Ensembl chr 8:143,553,207...143,563,062 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 multiple interactions EXP [GSTP1 protein co-treated with Glutathione] inhibits the reaction [[Adenosine Triphosphate results in increased metabolism of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-amino-1-methyl-6-phenolimidazo(4,5-b)pyridine-DNA adduct]; [GSTP1 protein co-treated with Glutathione] inhibits the reaction [Adenosine Triphosphate results in increased activity of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine] CTD PMID:11196146 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G H2AX H2A.X variant histone multiple interactions EXP Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]; AZ10606120 inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]]; U 0126 inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]] CTD PMID:32941855 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465 		JBrowse link
G HCK HCK proto-oncogene, Src family tyrosine kinase multiple interactions
affects binding		 EXP [Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] inhibits the reaction [HCK protein binds to Adenosine Triphosphate] CTD PMID:33617879 NCBI chr20:32,052,242...32,101,856
Ensembl chr20:32,052,197...32,101,856 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions EXP Adenosine Triphosphate inhibits the reaction [protoporphyrin IX results in decreased activity of HIF1A protein] CTD PMID:23624237 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HK1 hexokinase 1 multiple interactions EXP [Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of HK1 protein; HK1 protein affects the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of CASP1 protein]; HK1 protein affects the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased cleavage of GSDMD protein]; HK1 protein affects the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of IL1B protein]; HK1 protein affects the reaction [hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of CASP1 protein]]; HK1 protein affects the reaction [hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased cleavage of GSDMD protein]]; HK1 protein affects the reaction [hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of IL1B protein]]; hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of HK1 protein] CTD PMID:37001609 NCBI chr10:69,270,000...69,401,882
Ensembl chr10:69,269,984...69,401,884 		JBrowse link
G HK2 hexokinase 2 multiple interactions ISO [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of HK2 mRNA; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of HK2 protein CTD PMID:36577999 NCBI chr 2:74,834,127...74,893,359
Ensembl chr 2:74,834,127...74,893,359 		JBrowse link
G HMGB1 high mobility group box 1 affects chemical synthesis
multiple interactions		 ISO HMGB1 protein affects the chemical synthesis of Adenosine Triphosphate
[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased cleavage of CASP1 protein; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of CASP1 mRNA; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of IL18 mRNA; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of IL1B mRNA; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of MYD88 protein; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of NLRP3 mRNA; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of NLRP3 protein; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of PYCARD mRNA; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of PYCARD protein; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of TLR4 protein; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased phosphorylation of MAPK1 protein; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased phosphorylation of MAPK3 protein; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased phosphorylation of RELA protein; Adenosine Triphosphate promotes the reaction [fullerene C60 results in increased secretion of HMGB1 protein]; Adenosine Triphosphate promotes the reaction [graphene oxide results in increased secretion of HMGB1 protein]; Adenosine Triphosphate promotes the reaction [Nanotubes, Carbon results in increased secretion of HMGB1 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased cleavage of CASP1 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of CASP1 mRNA]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of IL18 mRNA]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of IL1B mRNA]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of MYD88 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of NLRP3 mRNA]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of NLRP3 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of PYCARD mRNA]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of PYCARD protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of TLR4 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased phosphorylation of MAPK1 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased phosphorylation of MAPK3 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased phosphorylation of RELA protein]		 CTD PMID:21641551 PMID:31504961 PMID:34405489 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions EXP [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of HMOX1 protein; Luteolin promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of HMOX1 protein] CTD PMID:34217685 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to HSP90AA1 protein]; Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]; Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]] CTD PMID:23184943 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of HSPA5 mRNA; [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of HSPA5 protein; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of HSPA5 mRNA]; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of HSPA5 protein] CTD PMID:24149798 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 affects chemical synthesis ISO HSPB1 protein affects the chemical synthesis of Adenosine Triphosphate CTD PMID:21641551 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 multiple interactions
increases expression		 ISO bisindolylmaleimide I inhibits the reaction [Adenosine Triphosphate results in increased expression of HSPD1 protein]; chelerythrine inhibits the reaction [Adenosine Triphosphate results in increased expression of HSPD1 protein]; Neomycin inhibits the reaction [Adenosine Triphosphate results in increased expression of HSPD1 protein]; resveratrol inhibits the reaction [Adenosine Triphosphate results in increased expression of HSPD1 protein]; tricyclodecane-9-yl-xanthogenate inhibits the reaction [Adenosine Triphosphate results in increased expression of HSPD1 protein] CTD PMID:16178011 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions EXP Adenosine Triphosphate inhibits the reaction [Fructose results in increased expression of ICAM1 protein] CTD PMID:18508964 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IFNG interferon gamma multiple interactions ISO Adenosine Triphosphate promotes the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased abundance of Dinoprostone] CTD PMID:14623498 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL12B interleukin 12B multiple interactions EXP Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein] CTD PMID:17707769 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G IL18 interleukin 18 multiple interactions
increases secretion		 EXP
ISO		 [Adenosine Triphosphate co-treated with K-12 lipopolysaccharide] results in increased secretion of IL18 protein; [Disulfiram co-treated with Adenosine Triphosphate] inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL18 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 mRNA; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein]; Resveratrol promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 mRNA]; Resveratrol promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein]; ubiquinone-O inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein]
[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein]]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein]
Adenosine Triphosphate results in increased secretion of IL18 protein
3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL18 protein]; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of IL18 mRNA; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL18 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 mRNA; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein; Acetylcysteine inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL18 protein]; diphenyleneiodonium inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL18 protein]; Hirudins inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein]; lonidamine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of IL18 mRNA]		 CTD PMID:17404311 PMID:24149798 PMID:26431797 PMID:27311643 PMID:31993881 More... NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL1A interleukin 1 alpha multiple interactions ISO (N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1A protein]; (N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) inhibits the reaction [Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein]]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1A protein; Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein] CTD PMID:26068648 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta multiple interactions
increases secretion
decreases abundance		 ISO
EXP		 [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein; Enzyme Inhibitors inhibits the reaction [IL1B protein results in decreased abundance of Adenosine Triphosphate]; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]; IL1B protein inhibits the reaction [Adenosine Triphosphate results in increased secretion of INS1 protein]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]; Quercetin inhibits the reaction [IL1B protein inhibits the reaction [Adenosine Triphosphate results in increased secretion of INS1 protein]]
Adenosine Triphosphate results in increased secretion of IL1B protein
(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; (N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) inhibits the reaction [Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]; 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL1B protein]; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of IL1B mRNA; [Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B mRNA; [Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of and results in increased secretion of IL1B protein; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of IL1B mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased secretion of and results in increased cleavage of IL1B protein; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of and results in increased cleavage of IL1B protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of and results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased activity of and results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B mRNA; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of and results in increased cleavage of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein; Acetylcysteine inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL1B protein]; Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; Adenosine Triphosphate promotes the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased abundance of Dinoprostone]; Adenosine Triphosphate promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; Adenosine Triphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Arsenic Trioxide inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B mRNA]; Chlorquinaldol inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; diphenyleneiodonium inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL1B protein]; fuzheng huayu inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of IL1B mRNA]; fuzheng huayu inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased secretion of and results in increased cleavage of IL1B protein]; fuzheng huayu inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; ginsenoside Rg3 inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; gypenoside LXXV inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; Hirudins inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; lonidamine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of and affects the cleavage of IL1B protein]; mitochondrial uncoupler BAM15 inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B mRNA]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of IL1B protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketone inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of and results in increased secretion of IL1B protein]; Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B mRNA]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of and results in increased cleavage of IL1B protein]; Okadaic Acid inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; PML protein promotes the reaction [[resiquimod co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]; PYCARD protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of and results in increased cleavage of IL1B protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of IL1B mRNA]; zinc chloride inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]]
3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; [Adenosine Triphosphate co-treated with K-12 lipopolysaccharide] results in increased secretion of IL1B protein modified form; [Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B mRNA; [Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased cleavage of IL1B protein; [Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of IL1B protein; [Disulfiram co-treated with Adenosine Triphosphate] inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of and results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased cleavage of and results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B mRNA; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein; Adenosine Triphosphate promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL1B protein]; Adenosine Triphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Adenosine Triphosphate results in increased cleavage of and results in increased secretion of IL1B protein; Apigenin inhibits the reaction [Adenosine Triphosphate results in increased cleavage of and results in increased secretion of IL1B protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B mRNA]; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; flavone analog inhibits the reaction [Adenosine Triphosphate results in increased cleavage of and results in increased secretion of IL1B protein]; HK1 protein affects the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of IL1B protein]; HK1 protein affects the reaction [hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of IL1B protein]]; hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased cleavage of IL1B protein]; hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of IL1B protein]; KN 62 inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of IL1B protein]; L 709049 inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; Luteolin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]; mitochondrial uncoupler BAM15 inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B mRNA]; MitoTEMPO inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B mRNA]; Resveratrol inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL1B protein]; Resveratrol inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B mRNA]; Resveratrol promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; tyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone analog inhibits the reaction [Adenosine Triphosphate results in increased cleavage of and results in increased secretion of IL1B protein]; ubiquinone-O inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B mRNA]		 CTD PMID:10365824 PMID:14623498 PMID:17404311 PMID:18604214 PMID:19130485 More... NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions
increases expression		 EXP
ISO		 [Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of IL6 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL6 protein; Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL6 protein]; hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of IL6 protein]; NF157 compound inhibits the reaction [Adenosine Triphosphate results in increased expression of IL6 protein]; sodium arsenite promotes the reaction [Adenosine Triphosphate results in increased expression of IL6 protein]; Suramin inhibits the reaction [Adenosine Triphosphate results in increased expression of IL6 protein]
Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]; coomassie Brilliant Blue inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; resveratrol inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; SB 203580 inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]
[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of IL6 mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased secretion of IL6 protein; azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased expression of IL6 protein]; fuzheng huayu inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of IL6 mRNA]; fuzheng huayu inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased secretion of IL6 protein]; MRS 2211 inhibits the reaction [Adenosine Triphosphate results in increased expression of IL6 protein]		 CTD PMID:17707769 PMID:24793913 PMID:24849676 PMID:25348860 PMID:26104857 More... NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INS insulin multiple interactions EXP [ammonium ferrous sulfate results in increased activity of INS protein modified form] which results in increased secretion of Adenosine Triphosphate; [chromic chloride results in increased activity of INS protein modified form] which results in increased secretion of Adenosine Triphosphate; INS protein inhibits the reaction [Acetaminophen results in decreased abundance of Adenosine Triphosphate]; Mannose inhibits the reaction [[chromic chloride results in increased activity of INS protein modified form] which results in increased secretion of Adenosine Triphosphate]; Phloretin inhibits the reaction [[chromic chloride results in increased activity of INS protein modified form] which results in increased secretion of Adenosine Triphosphate] CTD PMID:17965850 PMID:26739624 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
G INS-IGF2 INS-IGF2 readthrough increases secretion
multiple interactions		 ISO Adenosine Triphosphate results in increased secretion of INS1 protein
Adenosine Triphosphate inhibits the reaction [Glucose results in increased secretion of INS1 protein]
[[Glucose co-treated with INS1 protein] results in increased abundance of Adenosine Triphosphate] which results in increased secretion of LEP protein; [Glucose co-treated with INS1 protein] results in increased abundance of Adenosine Triphosphate; IL1B protein inhibits the reaction [Adenosine Triphosphate results in increased secretion of INS1 protein]; Quercetin inhibits the reaction [IL1B protein inhibits the reaction [Adenosine Triphosphate results in increased secretion of INS1 protein]]; SIRT1 protein promotes the reaction [[Glucose results in increased abundance of Adenosine Triphosphate] which results in increased expression of INS1 protein]		 CTD PMID:10535451 PMID:10780946 PMID:16366736 PMID:22221676 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209 		JBrowse link
G IRF2 interferon regulatory factor 2 multiple interactions ISO [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IRF2 mRNA; Hirudins inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IRF2 mRNA] CTD PMID:34212273 NCBI chr 4:184,387,729...184,474,550
Ensembl chr 4:184,385,702...184,474,558 		JBrowse link
G ITGB1BP2 integrin subunit beta 1 binding protein 2 multiple interactions EXP
ISO		 Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to PPP5C protein]; Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to SUGT1 protein]; Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to SUGT1 protein]]
Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to CHORDC1 protein]; Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]; Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to ITGB1BP2 protein]; Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]]		 CTD PMID:23184943 NCBI chr  X:71,301,750...71,305,371
Ensembl chr  X:71,301,750...71,305,371 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of JUN protein; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of JUN protein] CTD PMID:24149798 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 increases abundance
multiple interactions		 EXP KCND2 protein results in increased abundance of Adenosine Triphosphate
[[FAM66C mRNA binds to and results in decreased expression of MIR23 mRNA] which results in increased expression of KCND2 protein] which results in increased abundance of Adenosine Triphosphate; [[MIR23B mRNA binds to KCND2 3' UTR] which results in decreased expression of KCND2 protein] which results in decreased abundance of Adenosine Triphosphate		 CTD PMID:34418280 NCBI chr 7:120,272,908...120,750,337
Ensembl chr 7:120,273,175...120,750,337 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 decreases activity EXP Adenosine Triphosphate deficiency results in decreased activity of KCNH2 protein CTD PMID:12531891 NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 multiple interactions
decreases response to substance		 ISO Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]; Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]; Creatine metabolite inhibits the reaction [Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]]
KCNJ11 protein mutant form results in decreased susceptibility to Adenosine Triphosphate		 CTD PMID:11390963 PMID:28842488 NCBI chr11:17,385,248...17,389,346
Ensembl chr11:17,365,172...17,389,331 		JBrowse link
G KCNJ15 potassium inwardly rectifying channel subfamily J member 15 increases activity EXP Adenosine Triphosphate results in increased activity of KCNJ15 protein CTD PMID:15328350 NCBI chr21:38,229,926...38,307,357
Ensembl chr21:38,155,549...38,307,357 		JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 multiple interactions
decreases response to substance		 ISO Adenosine Triphosphate results in decreased activity of [KCNJ8 protein binds to ABCC9 protein]
KCNJ8 protein mutant form results in decreased susceptibility to Adenosine Triphosphate		 CTD PMID:28842488 NCBI chr12:21,764,955...21,774,706
Ensembl chr12:21,764,955...21,775,600 		JBrowse link
G KHK ketohexokinase multiple interactions EXP KHK protein promotes the reaction [Fructose results in decreased abundance of Adenosine Triphosphate] CTD PMID:19158351 NCBI chr 2:27,086,772...27,100,762
Ensembl chr 2:27,086,772...27,100,762 		JBrowse link
G KIF5A kinesin family member 5A multiple interactions
increases hydrolysis		 EXP Adenosine Triphosphate inhibits the reaction [zinc chloride results in decreased activity of KIF5A protein]; Cadmium Chloride inhibits the reaction [KIF5A protein results in increased hydrolysis of Adenosine Triphosphate]; Egtazic Acid inhibits the reaction [Cadmium Chloride inhibits the reaction [KIF5A protein results in increased hydrolysis of Adenosine Triphosphate]] CTD PMID:24239783 PMID:28122263 NCBI chr12:57,550,044...57,586,633
Ensembl chr12:57,546,026...57,586,633 		JBrowse link
G LEP leptin multiple interactions ISO [[Glucose co-treated with INS1 protein] results in increased abundance of Adenosine Triphosphate] which results in increased secretion of LEP protein; [Deoxyglucose results in decreased abundance of Adenosine Triphosphate] which results in decreased secretion of LEP protein CTD PMID:10780946 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G LIPE lipase E, hormone sensitive type increases activity EXP Adenosine Triphosphate results in increased activity of LIPE protein CTD PMID:7155675 NCBI chr19:42,401,514...42,427,388
Ensembl chr19:42,401,514...42,427,388 		JBrowse link
G LPL lipoprotein lipase affects response to substance EXP LPL protein affects the susceptibility to Adenosine Triphosphate CTD PMID:11786490 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 affects binding ISO Adenosine Triphosphate binds to MAP2K1 protein CTD PMID:17693661 NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation
increases activity		 EXP
ISO		 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Adenosine Triphosphate results in increased phosphorylation of MAPK1 protein]; [Alcohols co-treated with Adenosine Triphosphate] results in increased activity of MAPK1 protein; Alcohols inhibits the reaction [Adenosine Triphosphate results in increased activity of MAPK1 protein]; AZ10606120 inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased phosphorylation of MAPK1 protein]]; sodium arsenite promotes the reaction [Adenosine Triphosphate results in increased phosphorylation of MAPK1 protein]
[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased phosphorylation of MAPK1 protein; azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased phosphorylation of MAPK1 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased phosphorylation of MAPK1 protein]		 CTD PMID:12513686 PMID:15034929 PMID:21503959 PMID:24300283 PMID:26104857 More... NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation
increases activity		 EXP
ISO		 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Adenosine Triphosphate results in increased phosphorylation of MAPK3 protein]; [Alcohols co-treated with Adenosine Triphosphate] results in increased activity of MAPK3 protein; Alcohols inhibits the reaction [Adenosine Triphosphate results in increased activity of MAPK3 protein]; AZ10606120 inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased phosphorylation of MAPK3 protein]]; sodium arsenite promotes the reaction [Adenosine Triphosphate results in increased phosphorylation of MAPK3 protein]
[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased phosphorylation of MAPK3 protein; azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased phosphorylation of MAPK3 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased phosphorylation of MAPK3 protein]		 CTD PMID:12513686 PMID:15034929 PMID:21503959 PMID:24300283 PMID:26104857 More... NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPT microtubule associated protein tau multiple interactions ISO [annonacin results in decreased abundance of Adenosine Triphosphate] which affects the localization of MAPT protein CTD PMID:17634376 NCBI chr17:45,894,554...46,028,334
Ensembl chr17:45,894,527...46,028,334 		JBrowse link
G METRNL meteorin like, glial cell differentiation regulator multiple interactions ISO METRNL protein inhibits the reaction [Dietary Fats results in decreased abundance of Adenosine Triphosphate] CTD PMID:30213948 NCBI chr17:83,079,609...83,095,122
Ensembl chr17:83,079,609...83,095,122 		JBrowse link
G MFN2 mitofusin 2 decreases response to substance
multiple interactions
increases chemical synthesis		 ISO
EXP		 MFN2 results in decreased susceptibility to Adenosine Triphosphate deficiency
MFN2 protein inhibits the reaction [TNF protein results in decreased chemical synthesis of Adenosine Triphosphate]
MFN2 protein results in increased chemical synthesis of Adenosine Triphosphate
MFN2 protein inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased chemical synthesis of Adenosine Triphosphate]		 CTD PMID:22292091 PMID:24898700 PMID:25416777 NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211 		JBrowse link
G MIR219A1 microRNA 219a-1 multiple interactions ISO [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in decreased expression of MIR219A1 mRNA; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]]; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein]]; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein]]; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]]; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]]; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein]]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein] CTD PMID:35962723 NCBI chr 6:33,207,835...33,207,944
Ensembl chr 6:33,207,835...33,207,944 		JBrowse link
G MIR23B microRNA 23b decreases abundance
multiple interactions		 EXP MIR23B mRNA results in decreased abundance of Adenosine Triphosphate
[[MIR23B mRNA binds to KCND2 3' UTR] which results in decreased expression of KCND2 protein] which results in decreased abundance of Adenosine Triphosphate		 CTD PMID:34418280 NCBI chr 9:95,085,208...95,085,304
Ensembl chr 9:95,085,208...95,085,304 		JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions EXP [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of MMP2 mRNA; ubiquinone-O inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of MMP2 mRNA] CTD PMID:36847822 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions
increases activity
increases secretion		 ISO
EXP		 1,10-phenanthroline inhibits the reaction [Adenosine Triphosphate results in increased activity of MMP9 protein]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Adenosine Triphosphate results in increased activity of MMP9 protein]; SB 3CT compound inhibits the reaction [Adenosine Triphosphate results in increased activity of MMP9 protein]; wortmannin inhibits the reaction [Adenosine Triphosphate results in increased activity of MMP9 protein]
[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of MMP9 mRNA; ubiquinone-O inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of MMP9 mRNA]
azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased expression of MMP9 protein]
Adenosine Triphosphate results in increased secretion of MMP9 protein		 CTD PMID:20195827 PMID:26522449 PMID:36847822 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MT-ATP6 mitochondrially encoded ATP synthase membrane subunit 6 affects abundance ISO ATP6 protein affects the abundance of Adenosine Triphosphate CTD PMID:18273840 NCBI chr MT:8,527...9,207
Ensembl chr MT:8,527...9,207 		JBrowse link
G MT-CO3 mitochondrially encoded cytochrome c oxidase III increases abundance EXP COX3 protein results in increased abundance of Adenosine Triphosphate CTD PMID:17428446 NCBI chr MT:9,207...9,990
Ensembl chr MT:9,207...9,990 		JBrowse link
G MVD mevalonate diphosphate decarboxylase increases hydrolysis EXP MVD protein results in increased hydrolysis of Adenosine Triphosphate CTD PMID:9392419 NCBI chr16:88,651,940...88,663,091
Ensembl chr16:88,651,935...88,663,161 		JBrowse link
G MVK mevalonate kinase increases hydrolysis
multiple interactions		 EXP MVK protein results in increased hydrolysis of Adenosine Triphosphate
3,3-dimethylallyl pyrophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; dolichol monophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; Farnesol inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; farnesyl pyrophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; geranyl diphosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; geranylgeranyl pyrophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; isopentenyl pyrophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]		 CTD PMID:9392419 NCBI chr12:109,573,272...109,598,125
Ensembl chr12:109,573,255...109,598,125 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor multiple interactions ISO [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of MYD88 protein; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of MYD88 protein; fuzheng huayu inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of MYD88 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of MYD88 protein] CTD PMID:34405489 PMID:37544346 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G MYH7 myosin heavy chain 7 increases abundance EXP MYH7 gene mutant form results in increased abundance of Adenosine Triphosphate CTD PMID:29741611 NCBI chr14:23,412,740...23,435,660
Ensembl chr14:23,412,740...23,435,660 		JBrowse link
G NADSYN1 NAD synthetase 1 multiple interactions EXP [Ammonium Chloride co-treated with nicotinic acid adenine dinucleotide co-treated with Adenosine Triphosphate] results in increased activity of NADSYN1 protein; [NADSYN1 protein co-treated with Ammonium Chloride co-treated with nicotinic acid adenine dinucleotide co-treated with Adenosine Triphosphate] results in increased chemical synthesis of NAD CTD PMID:12547821 NCBI chr11:71,453,203...71,501,816
Ensembl chr11:71,453,109...71,524,107 		JBrowse link
G NCS1 neuronal calcium sensor 1 multiple interactions
increases response to substance		 ISO NCS1 protein promotes the reaction [Adenosine Triphosphate results in increased secretion of GH1 protein]; oxophenylarsine inhibits the reaction [NCS1 protein promotes the reaction [Adenosine Triphosphate results in increased secretion of GH1 protein]]
NCS1 protein results in increased susceptibility to Adenosine Triphosphate		 CTD PMID:12471042 NCBI chr 9:130,172,404...130,237,303
Ensembl chr 9:130,172,404...130,237,303 		JBrowse link
G NFATC1 nuclear factor of activated T cells 1 affects localization
multiple interactions		 ISO Adenosine Triphosphate affects the localization of NFATC1 protein
azetidine analog inhibits the reaction [Adenosine Triphosphate affects the localization of NFATC1 protein]		 CTD PMID:21464294 PMID:26522449 NCBI chr18:79,395,930...79,529,323
Ensembl chr18:79,395,856...79,529,325 		JBrowse link
G NFATC3 nuclear factor of activated T cells 3 affects localization ISO Adenosine Triphosphate affects the localization of NFATC3 protein CTD PMID:21464294 NCBI chr16:68,085,370...68,229,259
Ensembl chr16:68,084,751...68,229,259 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions EXP [Lipopolysaccharides co-treated with Adenosine Triphosphate] affects the localization of NFE2L2 protein; Luteolin promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] affects the localization of NFE2L2 protein] CTD PMID:34217685 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions ISO
EXP		 Adenosine Triphosphate promotes the reaction [RELA protein binds to NFKBIA protein]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to NFKBIA protein]]
[Adenosine Triphosphate co-treated with Lipopolysaccharides] affects the localization of NFKBIA protein; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] affects the localization of NFKBIA protein]		 CTD PMID:21464294 PMID:24149798 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NGF nerve growth factor multiple interactions ISO [NGF protein co-treated with Adenosine Triphosphate] results in increased uptake of Calcium CTD PMID:1374475 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770 		JBrowse link
G NLRP1 NLR family pyrin domain containing 1 multiple interactions EXP [Lipopolysaccharides co-treated with Adenosine Triphosphate co-treated with resveratrol] results in increased expression of NLRP1 mRNA CTD PMID:24149798 NCBI chr17:5,501,396...5,584,509
Ensembl chr17:5,499,415...5,619,424 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 multiple interactions EXP
ISO		 [Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NLRP3 protein; [Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NLRP3 protein; [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased activity of NLRP3 protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate co-treated with Resveratrol] results in increased expression of NLRP3 mRNA; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 mRNA; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein; Acetylcysteine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NLRP3 protein]; KN 62 inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; Luteolin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; mitochondrial uncoupler BAM15 inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NLRP3 protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NLRP3 protein]; ubiquinone-O inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]
[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]
[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of NLRP3 mRNA; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of NLRP3 protein; [Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NLRP3 protein; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased secretion of NLRP3 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to CASP1 protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PML protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PYCARD protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NLRP3 protein]; fuzheng huayu inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 mRNA]; fuzheng huayu inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased secretion of NLRP3 protein]; mitochondrial uncoupler BAM15 inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NLRP3 protein]; Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NLRP3 protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of and results in increased cleavage of IL1B protein]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to CASP1 protein]]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PYCARD protein]]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of NLRP3 mRNA]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of NLRP3 protein]		 CTD PMID:18604214 PMID:23430110 PMID:24149798 PMID:26086368 PMID:26586371 More... NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108 		JBrowse link
G NOLC1 nucleolar and coiled-body phosphoprotein 1 multiple interactions EXP Adenosine Triphosphate affects the reaction [Doxorubicin binds to NOLC1 protein] CTD PMID:17129415 NCBI chr10:102,152,389...102,163,870
Ensembl chr10:102,152,176...102,163,871 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions
increases expression		 EXP
ISO		 [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NOS2 protein; NOS2 protein affects the reaction [Adenosine Triphosphate results in increased metabolism of RELA protein]; ubiquinone-O inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NOS2 protein]
azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased expression of NOS2 protein]
[Adenosine Triphosphate results in increased expression of NOS2 protein] promotes the reaction [NOS2 protein binds to RELA protein]; Adenosine Triphosphate promotes the reaction [RELA protein binds to NOS2 protein]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to NOS2 protein]]; Cyclosporine inhibits the reaction [[Adenosine Triphosphate results in increased expression of NOS2 protein] promotes the reaction [NOS2 protein binds to RELA protein]]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Adenosine Triphosphate results in increased expression of NOS2 protein]; NOS2 protein affects the reaction [Adenosine Triphosphate results in increased abundance of Nitric Oxide]		 CTD PMID:21464294 PMID:26522449 PMID:36847822 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 multiple interactions EXP Adenosine Triphosphate affects the reaction [Alcohols affects the phosphorylation of NOS3 protein]; Adenosine Triphosphate inhibits the reaction [Alcohols results in decreased expression of NOS3 protein] CTD PMID:24300283 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NPY neuropeptide Y affects response to substance EXP NPY protein affects the susceptibility to Adenosine Triphosphate CTD PMID:15003356 NCBI chr 7:24,284,190...24,291,862
Ensembl chr 7:24,284,188...24,291,862 		JBrowse link
G NR4A1 nuclear receptor subfamily 4 group A member 1 increases expression ISO Adenosine Triphosphate results in increased expression of NR4A1 mRNA CTD PMID:10723097 NCBI chr12:52,022,832...52,059,503
Ensembl chr12:52,022,832...52,059,507 		JBrowse link
G OAS1 2'-5'-oligoadenylate synthetase 1 multiple interactions EXP [OAS1 protein results in increased metabolism of Adenosine Triphosphate] which results in increased chemical synthesis of 2',5'-oligoadenylate CTD PMID:15732009 NCBI chr12:112,906,962...112,933,219
Ensembl chr12:112,905,856...112,933,219 		JBrowse link
G OXT oxytocin/neurophysin I prepropeptide multiple interactions
increases secretion		 ISO Adenosine Triphosphate promotes the reaction [Phenylephrine results in increased secretion of OXT protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of OXT protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased secretion of OXT protein] CTD PMID:11102496 NCBI chr20:3,071,620...3,072,517
Ensembl chr20:3,071,620...3,072,517 		JBrowse link
G P2RX1 purinergic receptor P2X 1 multiple interactions
affects binding		 ISO geldanamycin promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX1]; herbimycin promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX1]; monorden promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX1]
ATP binds to P2rx1 protein		 CTD
RGD		 PMID:11930156 PMID:12237343 RGD:727431 NCBI chr17:3,896,592...3,916,465
Ensembl chr17:3,896,592...3,916,476 		JBrowse link
G P2RX2 purinergic receptor P2X 2 multiple interactions
affects activity
increases activity
affects response to substance		 ISO 1-amino-4-(3-(4,6-dichloro(1,3,5)triazine-2-ylamino)phenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]]; Acetylcysteine inhibits the reaction [Rotenone promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]]; Cadmium Chloride affects the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; cobaltous chloride affects the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; Copper promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; cupric chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; Dithiothreitol inhibits the reaction [Hydrogen Peroxide promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]]; Hydrogen Peroxide promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; Mercuric Chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; Mercury promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; methyl methanethiosulfonate inhibits the reaction [Hydrogen Peroxide promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]]; methyl methanethiosulfonate inhibits the reaction [Mercury promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]]; myxothiazol promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; nickel chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; palladium chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; Rotenone promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; zinc chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; Zinc promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]
ATP affects activity of rat P2x2 receptor in transfected glial cells
P2RX2 protein affects the susceptibility to Adenosine Triphosphate		 CTD
RGD		 PMID:15081800 PMID:16190872 PMID:19793987 PMID:21207957 PMID:16388598 RGD:1642662 NCBI chr12:132,618,776...132,622,388
Ensembl chr12:132,618,776...132,622,388 		JBrowse link
G P2RX3 purinergic receptor P2X 3 multiple interactions
increases activity
affects activity		 ISO Eugenol inhibits the reaction [P2RX3 protein affects the activity of Adenosine Triphosphate]
Adenosine Triphosphate results in increased activity of P2RX3 protein		 CTD PMID:19967073 PMID:27481062 NCBI chr11:57,335,950...57,372,396
Ensembl chr11:57,338,352...57,372,396 		JBrowse link
G P2RX4 purinergic receptor P2X 4 multiple interactions
increases activity		 ISO
EXP		 [Cadmium co-treated with Zinc] promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; [Mercury co-treated with Copper] inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; Cadmium promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; Cobalt promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; Copper inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; Copper inhibits the reaction [Zinc promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]]; Mercury inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; Zinc promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]
5-(3-bromophenyl)-1,3-dihydro-2H-benzofuro(3,2-e)-1,4-diazepin-2-one inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; [ginsenoside M1 co-treated with Adenosine Triphosphate] results in increased activity of P2RX4 protein; [Resveratrol co-treated with Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX4 mRNA; [Resveratrol co-treated with Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX4 protein; ginsenoside M1 promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; ginsenoside Rb1 promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; ginsenoside Rd promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; Ivermectin promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]		 CTD PMID:10737610 PMID:15629187 PMID:19793987 PMID:21638035 PMID:24149798 More... NCBI chr12:121,210,129...121,234,106
Ensembl chr12:121,210,065...121,234,106 		JBrowse link
G P2RX5 purinergic receptor P2X 5 affects transport ISO ATP affects transport ion flux of P2rx5 receptor RGD PMID:12237343 RGD:727431 NCBI chr17:3,673,227...3,696,155
Ensembl chr17:3,672,199...3,696,240 		JBrowse link
G P2RX7 purinergic receptor P2X 7 multiple interactions
increases response to substance
increases expression
decreases response to substance
increases activity		 EXP
ISO		 [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 mRNA; [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 protein; Adenosine Triphosphate binds to and results in increased activity of P2RX7 protein; AZ 11645373 inhibits the reaction [Adenosine Triphosphate binds to and results in increased activity of P2RX7 protein]; AZ10606120 inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein]; calmidazolium inhibits the reaction [Adenosine Triphosphate binds to and results in increased activity of P2RX7 protein]; coomassie Brilliant Blue inhibits the reaction [Adenosine Triphosphate binds to and results in increased activity of P2RX7 protein]; KN 62 inhibits the reaction [Adenosine Triphosphate binds to and results in increased activity of P2RX7 protein]; P2RX7 protein affects the reaction [Adenosine Triphosphate results in increased secretion of SELL protein]; P2RX7 protein affects the reaction [Adenosine Triphosphate results in increased transport of Barium]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate binds to and results in increased activity of P2RX7 protein]; Resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 mRNA]; Resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 protein]; ZINC58368839 inhibits the reaction [Adenosine Triphosphate binds to and results in increased activity of P2RX7 protein]
P2RX7 protein results in increased susceptibility to Adenosine Triphosphate
Adenosine Triphosphate results in increased expression of P2RX7 protein
P2RX7 gene mutant form results in decreased susceptibility to Adenosine Triphosphate
3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein]; azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased expression of P2RX7 protein]; coomassie Brilliant Blue inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein]		 CTD PMID:11003599 PMID:17728465 PMID:19023039 PMID:21638035 PMID:23565201 More... NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032 		JBrowse link
G P2RY1 purinergic receptor P2Y1 multiple interactions
affects activity		 EXP
ISO		 [Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein] which results in increased abundance of Calcium; Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate inhibits the reaction [P2RY1 protein promotes the reaction [Adenosine Triphosphate results in decreased susceptibility to Hydrogen Peroxide]]; P2RY1 protein promotes the reaction [Adenosine Triphosphate results in decreased susceptibility to Hydrogen Peroxide]; Trichloroethylene inhibits the reaction [[Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein] which results in increased abundance of Calcium]
[N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate binds to and results in decreased activity of P2RY1 protein] inhibits the reaction [Adenosine Triphosphate results in increased uptake of Calcium]
Adenosine Triphosphate affects the activity of P2RY1 protein		 CTD PMID:12694404 PMID:15243297 PMID:16973929 PMID:22129738 NCBI chr 3:152,835,131...152,841,439
Ensembl chr 3:152,835,131...152,841,439 		JBrowse link
G P2RY11 purinergic receptor P2Y11 affects binding
multiple interactions		 EXP Adenosine Triphosphate binds to P2RY11 protein
[Adenosine Triphosphate binds to P2RY11 protein] which results in decreased expression of BCL2 protein; [Adenosine Triphosphate binds to P2RY11 protein] which results in increased susceptibility to Cisplatin		 CTD PMID:21503959 NCBI chr19:10,111,693...10,115,372
Ensembl chr19:10,111,693...10,115,372 		JBrowse link
G P2RY13 purinergic receptor P2Y13 multiple interactions EXP MRS 2211 inhibits the reaction [P2RY13 protein promotes the reaction [Adenosine Triphosphate results in decreased susceptibility to Hydrogen Peroxide]]; P2RY13 protein promotes the reaction [Adenosine Triphosphate results in decreased susceptibility to Hydrogen Peroxide] CTD PMID:22129738 NCBI chr 3:151,326,312...151,329,549
Ensembl chr 3:151,326,312...151,329,549 		JBrowse link
G P2RY2 purinergic receptor P2Y2 multiple interactions
affects activity
increases activity		 EXP
ISO		 [Adenosine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Calcium
[Adenosine Triphosphate results in increased activity of P2RY2 protein] which results in increased uptake of Calcium
Adenosine Triphosphate affects the activity of P2RY2 protein		 CTD PMID:11527950 PMID:15243297 PMID:17003265 NCBI chr11:73,218,281...73,242,427
Ensembl chr11:73,218,281...73,242,427 		JBrowse link
G P2RY4 pyrimidinergic receptor P2Y4 multiple interactions EXP [Adenosine Triphosphate binds to and results in increased activity of P2RY4 protein] which results in increased abundance of Calcium; Adenosine Triphosphate binds to and results in increased activity of P2RY4 protein; Trichloroethylene inhibits the reaction [[Adenosine Triphosphate binds to and results in increased activity of P2RY4 protein] which results in increased abundance of Calcium] CTD PMID:12694404 NCBI chr  X:70,258,166...70,260,204
Ensembl chr  X:70,258,166...70,260,204 		JBrowse link
G P2RY6 pyrimidinergic receptor P2Y6 multiple interactions EXP N,N''-1,4-butanediylbis(N'-(3-isothiocyanatophenyl))thiourea inhibits the reaction [P2RY6 protein promotes the reaction [Adenosine Triphosphate results in decreased susceptibility to Hydrogen Peroxide]]; P2RY6 protein promotes the reaction [Adenosine Triphosphate results in decreased susceptibility to Hydrogen Peroxide] CTD PMID:22129738 NCBI chr11:73,264,506...73,298,625
Ensembl chr11:73,264,498...73,305,103 		JBrowse link
G PANX1 pannexin 1 decreases activity
multiple interactions
increases export		 EXP
ISO		 Adenosine Triphosphate results in decreased activity of PANX1 protein
Carbenoxolone inhibits the reaction [PANX1 protein results in increased export of Adenosine Triphosphate]; Probenecid inhibits the reaction [PANX1 protein results in increased export of Adenosine Triphosphate]		 CTD PMID:19023039 PMID:19213873 NCBI chr11:94,128,841...94,181,968
Ensembl chr11:94,128,841...94,181,968 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions
increases expression		 EXP
ISO		 PARP1 mutant form inhibits the reaction [Cadmium results in decreased abundance of Adenosine Triphosphate]
PARP1 protein affects the reaction [pyrithione zinc results in decreased abundance of Adenosine Triphosphate]; PARP1 protein affects the reaction [Zinc results in decreased abundance of Adenosine Triphosphate]
Adenosine Triphosphate results in increased expression of PARP1 protein		 CTD PMID:17728843 PMID:19809895 PMID:21767558 PMID:22253048 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PDK1 pyruvate dehydrogenase kinase 1 affects response to substance
multiple interactions		 ISO PDK1 protein affects the susceptibility to Adenosine Triphosphate
[PDK1 protein affects the susceptibility to Adenosine Triphosphate] which affects the abundance of Calcium; Adenosine Triphosphate promotes the reaction [PDK1 protein affects the abundance of Calcium]; tubacin affects the reaction [[PDK1 protein affects the susceptibility to Adenosine Triphosphate] which affects the abundance of Calcium]		 CTD PMID:28887310 NCBI chr 2:172,555,373...172,724,312
Ensembl chr 2:172,555,373...172,608,669 		JBrowse link
G PFKM phosphofructokinase, muscle multiple interactions EXP Adenosine Triphosphate promotes the reaction [resveratrol results in decreased activity of PFKM protein] CTD PMID:23454376 NCBI chr12:48,105,353...48,146,404
Ensembl chr12:48,105,139...48,146,404 		JBrowse link
G PGP phosphoglycolate phosphatase decreases phosphorylation ISO PGP protein results in decreased phosphorylation of Adenosine Triphosphate CTD PMID:24338473 NCBI chr16:2,211,593...2,214,840
Ensembl chr16:2,211,593...2,214,840 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha multiple interactions
affects binding		 EXP 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine inhibits the reaction [Adenosine Triphosphate binds to PIK3CA protein]; Adenosine Triphosphate inhibits the reaction [resveratrol results in decreased activity of [PIK3R1 protein binds to PIK3CA protein]] CTD PMID:17550345 PMID:18754654 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions EXP Adenosine Triphosphate inhibits the reaction [resveratrol results in decreased activity of [PIK3R1 protein binds to PIK3CA protein]] CTD PMID:17550345 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821 		JBrowse link
G PLA2G4A phospholipase A2 group IVA increases activity ISO Adenosine Triphosphate results in increased activity of PLA2G4A protein CTD PMID:10535451 NCBI chr 1:186,828,949...186,988,981
Ensembl chr 1:186,828,949...186,988,981 		JBrowse link
G PLAU plasminogen activator, urokinase increases secretion ISO Adenosine Triphosphate results in increased secretion of PLAU protein CTD PMID:20177776 NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496 		JBrowse link
G PLPP3 phospholipid phosphatase 3 decreases chemical synthesis ISO PLPP3 gene mutant form results in decreased chemical synthesis of Adenosine Triphosphate CTD PMID:28982073 NCBI chr 1:56,494,761...56,579,563
Ensembl chr 1:56,494,761...56,645,301 		JBrowse link
G PML PML nuclear body scaffold multiple interactions ISO [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PML protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [PML protein binds to CASP1 protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of PML protein; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to CASP1 protein]]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PYCARD protein]]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased abundance of Reactive Oxygen Species]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; PML protein promotes the reaction [[resiquimod co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein] CTD PMID:23430110 NCBI chr15:73,994,716...74,047,827
Ensembl chr15:73,994,673...74,047,827 		JBrowse link
G PMVK phosphomevalonate kinase increases hydrolysis EXP PMVK protein results in increased hydrolysis of Adenosine Triphosphate CTD PMID:9392419 NCBI chr 1:154,924,740...154,942,658
Ensembl chr 1:154,924,740...154,936,719 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions ISO [Fenofibrate results in increased activity of PPARA protein] which results in decreased abundance of Adenosine Triphosphate CTD PMID:19593819 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions
decreases abundance		 EXP FASN protein promotes the reaction [rosiglitazone promotes the reaction [PPARG protein results in decreased abundance of Adenosine Triphosphate]]; rosiglitazone promotes the reaction [PPARG protein results in decreased abundance of Adenosine Triphosphate]; UCP1 protein promotes the reaction [PPARG protein mutant form results in decreased abundance of Adenosine Triphosphate]; UCP1 protein promotes the reaction [rosiglitazone promotes the reaction [PPARG protein results in decreased abundance of Adenosine Triphosphate]]
PPARG protein mutant form results in decreased abundance of Adenosine Triphosphate; PPARG protein results in decreased abundance of Adenosine Triphosphate		 CTD PMID:26670611 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PPP5C protein phosphatase 5 catalytic subunit multiple interactions EXP Adenosine Triphosphate binds to and affects the folding of PPP5C protein; Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to PPP5C protein]; Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to PPP5C protein] CTD PMID:23184943 NCBI chr19:46,347,087...46,390,975
Ensembl chr19:46,347,087...46,392,981 		JBrowse link
G PRDX2 peroxiredoxin 2 increases expression ISO Adenosine Triphosphate results in increased expression of PRDX2 protein modified form CTD PMID:16178011 NCBI chr19:12,796,823...12,801,800
Ensembl chr19:12,796,820...12,801,800 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions ISO [[PRKAA1 gene co-treated with PRKAA2 gene] affects the susceptibility to Metformin] which results in decreased abundance of Adenosine Triphosphate; [[PRKAA1 gene mutant form co-treated with PRKAA2 gene mutant form] affects the susceptibility to [Dihydroxyacetone co-treated with S 4048]] which results in decreased abundance of Adenosine Triphosphate; [[PRKAA1 gene mutant form co-treated with PRKAA2 gene mutant form] affects the susceptibility to [Glucose co-treated with S 4048]] which results in decreased abundance of Adenosine Triphosphate CTD PMID:31974165 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374 		JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 multiple interactions ISO [[PRKAA1 gene co-treated with PRKAA2 gene] affects the susceptibility to Metformin] which results in decreased abundance of Adenosine Triphosphate; [[PRKAA1 gene mutant form co-treated with PRKAA2 gene mutant form] affects the susceptibility to [Dihydroxyacetone co-treated with S 4048]] which results in decreased abundance of Adenosine Triphosphate; [[PRKAA1 gene mutant form co-treated with PRKAA2 gene mutant form] affects the susceptibility to [Glucose co-treated with S 4048]] which results in decreased abundance of Adenosine Triphosphate CTD PMID:31974165 NCBI chr 1:56,645,314...56,715,335
Ensembl chr 1:56,645,314...56,715,335 		JBrowse link
G PRKCA protein kinase C alpha multiple interactions EXP [[Adenosine Triphosphate co-treated with PRKCA protein] results in increased phosphorylation of RALBP1 protein] which results in increased transport of Doxorubicin CTD PMID:16087181 NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of PTGS2 protein; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of PTGS2 protein] CTD PMID:24149798 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PYCARD PYD and CARD domain containing multiple interactions EXP
ISO		 [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in decreased expression of PYCARD mRNA; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein]; Resveratrol inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in decreased expression of PYCARD mRNA]
[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein]]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein]
[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of PYCARD mRNA; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of PYCARD protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] promotes the reaction [PYCARD protein binds to CASP1 protein]; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] promotes the reaction [PYCARD protein binds to PYCARD protein]; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PYCARD protein]; lonidamine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] promotes the reaction [PYCARD protein binds to CASP1 protein]]; lonidamine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] promotes the reaction [PYCARD protein binds to PYCARD protein]]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PYCARD protein]]; PYCARD gene mutant form inhibits the reaction [Adenosine Triphosphate results in increased abundance of G(M3) Ganglioside]; PYCARD protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]; PYCARD protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of and results in increased cleavage of IL1B protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of PYCARD mRNA]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of PYCARD protein]		 CTD PMID:18604214 PMID:23430110 PMID:24149798 PMID:24475307 PMID:32721574 More... NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450 		JBrowse link
G RALBP1 ralA binding protein 1 multiple interactions EXP [[Adenosine Triphosphate co-treated with PRKCA protein] results in increased phosphorylation of RALBP1 protein] which results in increased transport of Doxorubicin; Adenosine Triphosphate promotes the reaction [RALBP1 protein affects the transport of Leukotriene C4] CTD PMID:15386349 PMID:16087181 NCBI chr18:9,475,009...9,538,114
Ensembl chr18:9,475,009...9,538,114 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP		 [Adenosine Triphosphate results in increased expression of NOS2 protein] promotes the reaction [NOS2 protein binds to RELA protein]; Adenosine Triphosphate promotes the reaction [RELA protein binds to ARRB2 protein]; Adenosine Triphosphate promotes the reaction [RELA protein binds to NFKBIA protein]; Adenosine Triphosphate promotes the reaction [RELA protein binds to NOS2 protein]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to ARRB2 protein]]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to NFKBIA protein]]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to NOS2 protein]]; Cyclosporine inhibits the reaction [[Adenosine Triphosphate results in increased expression of NOS2 protein] promotes the reaction [NOS2 protein binds to RELA protein]]
[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased phosphorylation of RELA protein; [Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of and results in increased phosphorylation of RELA protein; [Carbonyl Cyanide m-Chlorophenyl Hydrazone co-treated with Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of RELA protein; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased phosphorylation of RELA protein; [mitochondrial uncoupler BAM15 co-treated with Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of RELA protein; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of RELA protein]; fuzheng huayu inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased phosphorylation of RELA protein]; mitochondrial uncoupler BAM15 inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of RELA protein]; Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of and results in increased phosphorylation of RELA protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased phosphorylation of RELA protein]
[Adenosine Triphosphate co-treated with Lipopolysaccharides] affects the localization of RELA protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased phosphorylation of and affects the localization of RELA protein; Luteolin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased phosphorylation of and affects the localization of RELA protein]; NOS2 protein affects the reaction [Adenosine Triphosphate results in increased metabolism of RELA protein]; Resveratrol promotes the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] affects the localization of RELA protein]; S-Nitrosoglutathione promotes the reaction [Adenosine Triphosphate results in increased metabolism of RELA protein]		 CTD PMID:21464294 PMID:24149798 PMID:33524445 PMID:34217685 PMID:34405489 More... NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RHOF ras homolog family member F, filopodia associated increases expression
multiple interactions		 EXP
ISO		 Adenosine Triphosphate results in increased expression of RHOF mRNA
Niclosamide inhibits the reaction [Adenosine Triphosphate results in increased expression of RHOF mRNA]		 CTD PMID:29733962 NCBI chr12:121,777,754...121,793,688
Ensembl chr12:121,777,754...121,803,403 		JBrowse link
G S100A10 S100 calcium binding protein A10 increases expression EXP Adenosine Triphosphate results in increased expression of S100A10 mRNA CTD PMID:29733962 NCBI chr 1:151,982,915...151,993,859
Ensembl chr 1:151,982,915...151,993,859 		JBrowse link
G S100A11 S100 calcium binding protein A11 increases expression EXP Adenosine Triphosphate results in increased expression of S100A11 mRNA CTD PMID:29733962 NCBI chr 1:152,032,506...152,037,004
Ensembl chr 1:152,032,506...152,047,907 		JBrowse link
G S100A4 S100 calcium binding protein A4 increases expression
multiple interactions		 ISO
EXP		 Adenosine Triphosphate results in increased expression of S100A4 mRNA
Adenosine Triphosphate results in increased expression of and results in increased secretion of S100A4 protein; Niclosamide inhibits the reaction [Adenosine Triphosphate results in increased expression of S100A4 protein]		 CTD PMID:29733962 NCBI chr 1:153,543,621...153,545,806
Ensembl chr 1:153,543,613...153,550,136 		JBrowse link
G S100A6 S100 calcium binding protein A6 increases expression EXP Adenosine Triphosphate results in increased expression of S100A6 mRNA CTD PMID:29733962 NCBI chr 1:153,534,599...153,535,991
Ensembl chr 1:153,534,599...153,536,244 		JBrowse link
G S100P S100 calcium binding protein P increases expression EXP Adenosine Triphosphate results in increased expression of S100P mRNA CTD PMID:29733962 NCBI chr 4:6,693,878...6,697,170
Ensembl chr 4:6,693,878...6,697,170 		JBrowse link
G SELL selectin L multiple interactions EXP P2RX7 protein affects the reaction [Adenosine Triphosphate results in increased secretion of SELL protein] CTD PMID:11003599 NCBI chr 1:169,690,667...169,711,620
Ensembl chr 1:169,690,665...169,711,702 		JBrowse link
G SFTPA1 surfactant protein A1 multiple interactions EXP [SFTPA1 protein polymorphism binds to SFTPA2 protein polymorphism] inhibits the reaction [Adenosine Triphosphate results in increased secretion of Phosphatidylcholines]; Ozone inhibits the reaction [[SFTPA1 protein polymorphism binds to SFTPA2 protein polymorphism] inhibits the reaction [Adenosine Triphosphate results in increased secretion of Phosphatidylcholines]]; Ozone inhibits the reaction [SFTPA1 protein polymorphism inhibits the reaction [Adenosine Triphosphate results in increased secretion of Phosphatidylcholines]] CTD PMID:15065867 NCBI chr10:79,610,939...79,615,455
Ensembl chr10:79,610,939...79,615,455 		JBrowse link
G SFTPA2 surfactant protein A2 multiple interactions EXP [SFTPA1 protein polymorphism binds to SFTPA2 protein polymorphism] inhibits the reaction [Adenosine Triphosphate results in increased secretion of Phosphatidylcholines]; Ozone inhibits the reaction [[SFTPA1 protein polymorphism binds to SFTPA2 protein polymorphism] inhibits the reaction [Adenosine Triphosphate results in increased secretion of Phosphatidylcholines]]; Ozone inhibits the reaction [SFTPA2 protein polymorphism inhibits the reaction [Adenosine Triphosphate results in increased secretion of Phosphatidylcholines]]; SFTPA2 protein polymorphism inhibits the reaction [Adenosine Triphosphate results in increased secretion of Phosphatidylcholines] CTD PMID:15065867 NCBI chr10:79,555,852...79,560,407
Ensembl chr10:79,555,852...79,560,407 		JBrowse link
G SFTPB surfactant protein B increases secretion
multiple interactions		 ISO Adenosine Triphosphate results in increased secretion of SFTPB protein
Ro 31-8220 inhibits the reaction [Adenosine Triphosphate results in increased secretion of SFTPB protein]		 CTD PMID:11704537 PMID:14565945 NCBI chr 2:85,657,307...85,668,741
Ensembl chr 2:85,657,314...85,668,741 		JBrowse link
G SFTPC surfactant protein C increases secretion
multiple interactions		 ISO Adenosine Triphosphate results in increased secretion of SFTPC protein
Ro 31-8220 inhibits the reaction [Adenosine Triphosphate results in increased secretion of SFTPC protein]		 CTD PMID:11704537 PMID:14565945 NCBI chr 8:22,157,383...22,164,479
Ensembl chr 8:22,156,913...22,164,479 		JBrowse link
G SIRT1 sirtuin 1 multiple interactions ISO
EXP		 [SIRT1 protein results in decreased expression of UCP2 mRNA] promotes the reaction [Glucose results in increased abundance of Adenosine Triphosphate]; SIRT1 protein promotes the reaction [[Glucose results in increased abundance of Adenosine Triphosphate] which results in increased expression of INS1 protein]; SIRT1 protein promotes the reaction [Glucose results in increased abundance of Adenosine Triphosphate]
[STK11 protein co-treated with Adenosine Triphosphate] results in increased activity of and results in increased phosphorylation of SIRT1 protein		 CTD PMID:16366736 PMID:34216621 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G SIRT3 sirtuin 3 multiple interactions ISO SIRT3 protein inhibits the reaction [Metformin results in decreased abundance of Adenosine Triphosphate] CTD PMID:23166782 NCBI chr11:215,030...236,931
Ensembl chr11:215,030...236,931 		JBrowse link
G SLC25A14 solute carrier family 25 member 14 decreases chemical synthesis EXP SLC25A14 protein results in decreased chemical synthesis of Adenosine Triphosphate CTD PMID:20600837 NCBI chr  X:130,339,919...130,373,357
Ensembl chr  X:130,339,888...130,373,361 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 decreases stability EXP Adenosine Triphosphate results in decreased stability of SLC2A1 protein CTD PMID:11420438 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893 		JBrowse link
G SLC2A4 solute carrier family 2 member 4 increases abundance EXP SLC2A4 protein results in increased abundance of Adenosine Triphosphate CTD PMID:34904774 NCBI chr17:7,281,718...7,288,257
Ensembl chr17:7,281,718...7,288,257 		JBrowse link
G SLC46A1 solute carrier family 46 member 1 multiple interactions EXP [SLC46A1 protein results in increased susceptibility to N-((5-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo(2,3-d)pyrimidin-6-yl)propyl)thiophen-2-yl)carbonyl)glutamic acid] which results in decreased chemical synthesis of Adenosine Triphosphate CTD PMID:21879757 NCBI chr17:28,394,642...28,406,592
Ensembl chr17:28,394,642...28,407,197 		JBrowse link
G SLC5A5 solute carrier family 5 member 5 multiple interactions EXP Adenosine Triphosphate inhibits the reaction [TSHB protein results in increased expression of SLC5A5 protein] CTD PMID:16439463 NCBI chr19:17,871,945...17,895,174
Ensembl chr19:17,871,945...17,895,174 		JBrowse link
G SNCA synuclein alpha multiple interactions
decreases abundance		 EXP GW8510 inhibits the reaction [SNCA protein results in decreased abundance of Adenosine Triphosphate]; SB 216763 inhibits the reaction [SNCA protein results in decreased abundance of Adenosine Triphosphate] CTD PMID:24989254 NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315 		JBrowse link
G SOD1 superoxide dismutase 1 increases expression ISO
EXP		 Adenosine Triphosphate results in increased expression of SOD1 protein CTD PMID:16178011 PMID:22129738 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SOD2 superoxide dismutase 2 affects chemical synthesis
decreases abundance
multiple interactions		 ISO SOD2 protein affects the chemical synthesis of Adenosine Triphosphate
SOD2 gene mutant form results in decreased abundance of Adenosine Triphosphate
MK-886 promotes the reaction [SOD2 gene mutant form results in decreased abundance of Adenosine Triphosphate]		 CTD PMID:20638473 PMID:25362851 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SRR serine racemase multiple interactions ISO Adenosine Triphosphate inhibits the reaction [Edetic Acid inhibits the reaction [SRR protein results in increased abundance of D-Aspartic Acid]]; Adenosine Triphosphate promotes the reaction [SRR protein results in increased abundance of D-Aspartic Acid] CTD PMID:27387750 NCBI chr17:2,303,378...2,325,264
Ensembl chr17:2,303,383...2,325,260 		JBrowse link
G STK11 serine/threonine kinase 11 multiple interactions EXP [STK11 protein co-treated with Adenosine Triphosphate] results in increased activity of and results in increased phosphorylation of SIRT1 protein CTD PMID:34216621 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431 		JBrowse link
G STXBP2 syntaxin binding protein 2 multiple interactions ISO STXBP2 protein affects the reaction [F2 protein results in increased transport of Adenosine Triphosphate] CTD PMID:30696774 NCBI chr19:7,629,793...7,647,873
Ensembl chr19:7,636,772...7,647,873 		JBrowse link
G SUGT1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone multiple interactions EXP Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to SUGT1 protein]; Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to SUGT1 protein]; Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to SUGT1 protein]] CTD PMID:23184943 NCBI chr13:52,652,836...52,700,909
Ensembl chr13:52,652,709...52,700,909 		JBrowse link
G SYN2 synapsin II multiple interactions ISO SYN2 mutant form inhibits the reaction [Adenosine Triphosphate results in increased abundance of Calcium] CTD PMID:18701217 NCBI chr 3:12,004,388...12,192,032
Ensembl chr 3:12,004,388...12,192,032 		JBrowse link
G TAC1 tachykinin precursor 1 increases secretion
multiple interactions		 ISO Adenosine Triphosphate results in increased secretion of TAC1 protein
Iloprost promotes the reaction [Adenosine Triphosphate results in increased secretion of TAC1 protein]		 CTD PMID:16039053 NCBI chr 7:97,732,086...97,740,472
Ensembl chr 7:97,732,084...97,740,472 		JBrowse link
G TALDO1 transaldolase 1 increases abundance ISO TALDO1 gene mutant form results in increased abundance of Adenosine Triphosphate CTD PMID:19436114 NCBI chr11:747,464...765,012
Ensembl chr11:747,415...765,012 		JBrowse link
G TAS2R14 taste 2 receptor member 14 increases activity ISO Adenosine Triphosphate results in increased activity of TAS2R115 protein CTD PMID:29347925 NCBI chr12:10,937,410...11,171,611
Ensembl chr12:10,937,408...11,171,573 		JBrowse link
G TAS2R42 taste 2 receptor member 42 increases activity ISO Adenosine Triphosphate results in increased activity of TAS2R131 protein CTD PMID:29347925 NCBI chr12:11,185,993...11,186,937
Ensembl chr12:11,185,993...11,186,937 		JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions EXP [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased abundance of Adenosine Triphosphate CTD PMID:35366062 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TIMM17A translocase of inner mitochondrial membrane 17A multiple interactions
decreases expression		 EXP 1,10-phenanthroline inhibits the reaction [Adenosine Triphosphate results in decreased expression of TIMM17A protein] CTD PMID:24315374 NCBI chr 1:201,955,503...201,970,664
Ensembl chr 1:201,955,503...201,970,664 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 decreases secretion
multiple interactions		 ISO Adenosine Triphosphate results in decreased secretion of TIMP1 protein
azetidine analog inhibits the reaction [Adenosine Triphosphate results in decreased secretion of TIMP1 protein]		 CTD PMID:26522449 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
G TLR4 toll like receptor 4 multiple interactions ISO [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of TLR4 protein; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of TLR4 protein; fuzheng huayu inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of TLR4 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of TLR4 protein] CTD PMID:34405489 PMID:37544346 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TNF tumor necrosis factor multiple interactions
decreases chemical synthesis		 ISO
EXP		 [Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNF mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of TNF mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased secretion of TNF protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of TNF protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of TNF protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of TNF protein; Adenosine Triphosphate deficiency inhibits the reaction [TNF protein results in increased transport of Chlorides]; Adenosine Triphosphate deficiency inhibits the reaction [TNF protein results in increased transport of Potassium]; Adenosine Triphosphate promotes the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased abundance of Dinoprostone]; azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased secretion of TNF protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNF mRNA]; fuzheng huayu inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of TNF mRNA]; fuzheng huayu inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased secretion of TNF protein]; ginsenoside Rg3 inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of TNF protein]; gypenoside LXXV inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of TNF protein]; mitochondrial uncoupler BAM15 inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNF mRNA]; Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNF mRNA]
TNF protein results in decreased chemical synthesis of Adenosine Triphosphate
TNF protein promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased chemical synthesis of Adenosine Triphosphate]
[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of TNF protein; [Asbestos, Amosite co-treated with TNF protein] results in increased metabolism of Adenosine Triphosphate; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of TNF protein; Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of TNF protein]; hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of TNF protein]; MFN2 protein inhibits the reaction [TNF protein results in decreased chemical synthesis of Adenosine Triphosphate]; Rosiglitazone inhibits the reaction [TNF protein results in decreased chemical synthesis of Adenosine Triphosphate]; Vitamin K 3 promotes the reaction [[Asbestos, Amosite co-treated with TNF protein] results in increased metabolism of Adenosine Triphosphate]		 CTD PMID:8817062 PMID:10783394 PMID:14623498 PMID:17707769 PMID:23430110 More... NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFSF11 TNF superfamily member 11 increases abundance ISO TNFSF11 protein results in increased abundance of Adenosine Triphosphate CTD PMID:26287518 NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013 		JBrowse link
G TOP2A DNA topoisomerase II alpha multiple interactions
increases hydrolysis		 EXP Cannabidiol metabolite inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]; copper-thiosemicarbazone complex analog inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]; Dithiothreitol inhibits the reaction [Cannabidiol metabolite inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]]; Emodin inhibits the reaction [TOP2A results in increased hydrolysis of Adenosine Triphosphate]; Etoposide metabolite inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]; Thiosemicarbazones analog inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]
TOP2A protein results in increased hydrolysis of Adenosine Triphosphate; TOP2A results in increased hydrolysis of Adenosine Triphosphate		 CTD PMID:20855424 PMID:26982206 PMID:27533850 PMID:29272108 NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896 		JBrowse link
G TOP2B DNA topoisomerase II beta multiple interactions
increases hydrolysis		 EXP cannabidiol hydroxyquinone inhibits the reaction [TOP2B protein results in increased hydrolysis of Adenosine Triphosphate]; Cannabidiol metabolite inhibits the reaction [TOP2B protein results in increased hydrolysis of Adenosine Triphosphate] CTD PMID:29272108 NCBI chr 3:25,597,905...25,664,907
Ensembl chr 3:25,597,978...25,664,909 		JBrowse link
G TP53 tumor protein p53 multiple interactions
increases abundance		 EXP TP53 protein inhibits the reaction [Deoxyglucose results in decreased abundance of Adenosine Triphosphate]
TP53 gene mutant form results in increased abundance of Adenosine Triphosphate		 CTD PMID:21042727 PMID:33070465 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538 		JBrowse link
G TP53BP1 tumor protein p53 binding protein 1 multiple interactions EXP Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]; AZ10606120 inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]]; U 0126 inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]] CTD PMID:32941855 NCBI chr15:43,403,061...43,510,640
Ensembl chr15:43,403,061...43,510,728 		JBrowse link
G TRPC3 transient receptor potential cation channel subfamily C member 3 multiple interactions
increases activity		 ISO ethyl-1-(4-(2*3*3-trichloroacrylamide)phenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate inhibits the reaction [Adenosine Triphosphate results in increased activity of TRPC3 protein] CTD PMID:19289841 NCBI chr 4:121,874,481...121,952,060
Ensembl chr 4:121,874,481...121,952,060 		JBrowse link
G TRPC5 transient receptor potential cation channel subfamily C member 5 increases activity ISO Adenosine Triphosphate results in increased activity of TRPC5 protein CTD PMID:19289841 NCBI chr  X:111,768,011...112,082,776
Ensembl chr  X:111,768,011...112,082,776 		JBrowse link
G TRPC6 transient receptor potential cation channel subfamily C member 6 increases activity ISO Adenosine Triphosphate results in increased activity of TRPC6 protein CTD PMID:19289841 NCBI chr11:101,451,564...101,584,007
Ensembl chr11:101,451,564...101,872,562 		JBrowse link
G TRPC7 transient receptor potential cation channel subfamily C member 7 increases activity ISO Adenosine Triphosphate results in increased activity of TRPC7 protein CTD PMID:19289841 NCBI chr 5:136,212,745...136,365,545
Ensembl chr 5:136,212,745...136,365,545 		JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 decreases activity ISO Adenosine Triphosphate results in decreased activity of TRPM4 protein CTD PMID:16966582 PMID:17188667 NCBI chr19:49,157,792...49,211,836
Ensembl chr19:49,157,741...49,211,836 		JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 multiple interactions ISO [Capsaicin binds to and affects the activity of TRPV1 protein] which results in increased secretion of Adenosine Triphosphate CTD PMID:19860742 NCBI chr17:3,565,446...3,609,411
Ensembl chr17:3,565,444...3,609,411 		JBrowse link
G TSHB thyroid stimulating hormone subunit beta multiple interactions EXP Adenosine Triphosphate inhibits the reaction [TSHB protein results in increased expression of SLC5A5 protein] CTD PMID:16439463 NCBI chr 1:115,029,826...115,034,309
Ensembl chr 1:115,029,826...115,034,302 		JBrowse link
G TXN thioredoxin increases expression EXP Adenosine Triphosphate results in increased expression of TXN protein CTD PMID:22129738 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507 		JBrowse link
G TXNIP thioredoxin interacting protein increases activity ISO Adenosine Triphosphate results in increased activity of TXNIP mRNA CTD PMID:21832250 NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579 		JBrowse link
G UCP1 uncoupling protein 1 multiple interactions
decreases abundance		 ISO
EXP		 Adenosine Triphosphate inhibits the reaction [UCP1 protein results in increased transport of Protons]
UCP1 results in decreased abundance of Adenosine Triphosphate
UCP1 protein promotes the reaction [PPARG protein mutant form results in decreased abundance of Adenosine Triphosphate]; UCP1 protein promotes the reaction [rosiglitazone promotes the reaction [PPARG protein results in decreased abundance of Adenosine Triphosphate]]		 CTD PMID:12734183 PMID:26670611 NCBI chr 4:140,559,431...140,568,961
Ensembl chr 4:140,559,431...140,568,961 		JBrowse link
G UCP2 uncoupling protein 2 multiple interactions EXP
ISO		 Adenosine Triphosphate inhibits the reaction [UCP2 protein results in increased transport of Protons]
[SIRT1 protein results in decreased expression of UCP2 mRNA] promotes the reaction [Glucose results in increased abundance of Adenosine Triphosphate]		 CTD PMID:12734183 PMID:16366736 NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,672...73,982,843 		JBrowse link
G UCP3 uncoupling protein 3 multiple interactions EXP Adenosine Triphosphate inhibits the reaction [UCP3 protein results in increased transport of Protons] CTD PMID:12734183 NCBI chr11:74,000,277...74,009,085
Ensembl chr11:74,000,277...74,009,085 		JBrowse link
G VDAC1 voltage dependent anion channel 1 multiple interactions EXP VDAC1 mutant form inhibits the reaction [chromium hexavalent ion results in decreased abundance of Adenosine Triphosphate] CTD PMID:22858589 NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 decreases abundance
increases abundance
multiple interactions		 ISO XRCC1 gene mutant form results in decreased abundance of Adenosine Triphosphate
XRCC1 protein results in increased abundance of Adenosine Triphosphate
Acetylcysteine inhibits the reaction [XRCC1 gene mutant form results in decreased abundance of Adenosine Triphosphate]; Acetylcysteine promotes the reaction [XRCC1 protein results in increased abundance of Adenosine Triphosphate]		 CTD PMID:30998386 NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,311...43,580,473 		JBrowse link
bucladesine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 multiple interactions ISO [Bucladesine co-treated with APOA1 protein] results in increased expression of ABCA1 mRNA; [Bucladesine co-treated with APOA1 protein] results in increased expression of ABCA1 protein; [Bucladesine co-treated with LIPE protein] results in increased expression of ABCA1 protein; Oligomycins inhibits the reaction [[Bucladesine co-treated with APOA1 protein] results in increased expression of ABCA1 protein]; STAR protein promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased expression of ABCA1 mRNA] CTD PMID:20083572 PMID:23227865 PMID:23362264 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155 		JBrowse link
G ABCB11 ATP binding cassette subfamily B member 11 multiple interactions ISO Bucladesine inhibits the reaction [tert-Butylhydroperoxide affects the localization of ABCB11 protein] CTD PMID:16452108 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 multiple interactions
affects localization
increases activity
increases expression		 ISO
EXP		 Bucladesine inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein]; KT 5720 inhibits the reaction [Bucladesine affects the localization of ABCC2 protein]
Bucladesine results in increased activity of ABCC2 protein
Bucladesine results in increased expression of ABCC2 mRNA; Bucladesine results in increased expression of ABCC2 protein
Bucladesine promotes the reaction [ATF2 protein binds to ABCC2 promoter]; Bucladesine promotes the reaction [JUN protein binds to ABCC2 promoter]; Bucladesine results in increased activity of and affects the localization of ABCC2 protein; Dactinomycin inhibits the reaction [Bucladesine results in increased expression of ABCC2 mRNA]; KT 5720 inhibits the reaction [Bucladesine affects the localization of ABCC2 protein]; KT 5720 inhibits the reaction [Bucladesine results in increased expression of ABCC2 mRNA]; KT 5720 inhibits the reaction [Bucladesine results in increased expression of ABCC2 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of ABCC2 protein]; verlukast inhibits the reaction [Bucladesine results in increased activity of ABCC2 protein]		 CTD PMID:12029626 PMID:26049102 PMID:29052767 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ACHE acetylcholinesterase (Yt blood group) increases activity
increases expression		 ISO Bucladesine results in increased activity of ACHE protein; Bucladesine results in increased activity of ACHE protein alternative form
Bucladesine results in increased expression of ACHE mRNA		 CTD PMID:18514641 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974 		JBrowse link
G ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ADAMTS1 mRNA CTD PMID:20823114 NCBI chr21:26,835,755...26,845,409
Ensembl chr21:26,835,755...26,845,409 		JBrowse link
G ADM adrenomedullin decreases expression EXP Bucladesine results in decreased expression of ADM mRNA CTD PMID:19253104 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397 		JBrowse link
G AGT angiotensinogen multiple interactions EXP AGT protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of and results in increased localization of FOXO1 protein]; AGT protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased secretion of PRL protein]; Losartan inhibits the reaction [AGT protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased secretion of PRL protein]] CTD PMID:36682589 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AHR aryl hydrocarbon receptor affects localization
increases activity
multiple interactions		 ISO Bucladesine affects the localization of AHR protein
Bucladesine results in increased activity of AHR protein
Bucladesine affects the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]		 CTD PMID:15972329 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G AHRR aryl hydrocarbon receptor repressor multiple interactions ISO Bucladesine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHRR mRNA] CTD PMID:21979172 NCBI chr 5:321,714...438,285
Ensembl chr 5:321,714...438,291 		JBrowse link
G AK5 adenylate kinase 5 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of AK5 mRNA CTD PMID:20823114 NCBI chr 1:77,282,019...77,559,966
Ensembl chr 1:77,282,019...77,559,966 		JBrowse link
G ALAS1 5'-aminolevulinate synthase 1 multiple interactions ISO [NFE2L2 gene mutant form results in increased susceptibility to Bucladesine] which results in increased expression of ALAS1 mRNA CTD PMID:22859313 NCBI chr 3:52,198,083...52,214,327
Ensembl chr 3:52,198,086...52,214,327 		JBrowse link
G ANTXR1 ANTXR cell adhesion molecule 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of ANTXR1 mRNA CTD PMID:20823114 NCBI chr 2:69,013,144...69,249,327
Ensembl chr 2:69,013,176...69,249,327 		JBrowse link
G ANXA2 annexin A2 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ANXA2 mRNA CTD PMID:20823114 NCBI chr15:60,347,151...60,397,986
Ensembl chr15:60,347,134...60,402,883 		JBrowse link
G ANXA2P3 annexin A2 pseudogene 3 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ANXA2P3 mRNA CTD PMID:20823114 NCBI chr10:64,825,528...64,826,877
Ensembl chr10:64,825,572...64,826,579 		JBrowse link
G APOA1 apolipoprotein A1 multiple interactions ISO 27-hydroxycholesterol promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol]; 27-hydroxycholesterol promotes the reaction [STAR protein promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol]]; [Bucladesine co-treated with APOA1 protein] results in increased expression of ABCA1 mRNA; [Bucladesine co-treated with APOA1 protein] results in increased expression of ABCA1 protein; [Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol; Oligomycins inhibits the reaction [[Bucladesine co-treated with APOA1 protein] results in increased expression of ABCA1 protein]; Probucol inhibits the reaction [[Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol]; Probucol inhibits the reaction [STAR protein promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol]]; STAR protein promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased expression of ABCA1 mRNA]; STAR protein promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol]; T0901317 promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol] CTD PMID:20083572 PMID:23227865 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G AR androgen receptor multiple interactions ISO [Quercetin co-treated with Bucladesine] results in increased expression of AR mRNA CTD PMID:23200735 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619 		JBrowse link
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ARHGEF2 mRNA CTD PMID:20823114 NCBI chr 1:155,946,854...155,979,617
Ensembl chr 1:155,946,851...156,007,070 		JBrowse link
G ATF1 activating transcription factor 1 multiple interactions EXP Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [Dinoprostone results in increased phosphorylation of ATF1 protein]] CTD PMID:12164941 NCBI chr12:50,763,459...50,821,162
Ensembl chr12:50,763,710...50,821,162 		JBrowse link
G ATF2 activating transcription factor 2 multiple interactions
increases phosphorylation
increases expression		 EXP Bucladesine promotes the reaction [ATF2 protein binds to ABCC2 promoter]; Bucladesine promotes the reaction [JUN protein binds to ATF2 protein]; KT 5720 inhibits the reaction [Bucladesine results in increased expression of ATF2 protein modified form]
Bucladesine results in increased phosphorylation of ATF2 protein		 CTD PMID:26049102 NCBI chr 2:175,072,259...175,168,203
Ensembl chr 2:175,072,250...175,168,382 		JBrowse link
G ATP11A ATPase phospholipid transporting 11A multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of ATP11A mRNA CTD PMID:20823114 NCBI chr13:112,690,038...112,887,168
Ensembl chr13:112,690,038...112,887,168 		JBrowse link
G ATP2B1 ATPase plasma membrane Ca2+ transporting 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ATP2B1 mRNA CTD PMID:20823114 NCBI chr12:89,588,049...89,709,366
Ensembl chr12:89,588,049...89,709,366 		JBrowse link
G ATP6V0C ATPase H+ transporting V0 subunit c multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of ATP6V0C mRNA CTD PMID:20823114 NCBI chr16:2,513,726...2,520,218
Ensembl chr16:2,513,952...2,520,218 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP adenosine-3',5'-cyclic phosphorothioate inhibits the reaction [Bucladesine inhibits the reaction [Lipopolysaccharides results in increased expression of BAX protein]]; Bucladesine inhibits the reaction [Lipopolysaccharides results in increased expression of BAX protein] CTD PMID:16822680 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCAT1 branched chain amino acid transaminase 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of BCAT1 mRNA CTD PMID:20823114 NCBI chr12:24,810,024...24,949,340
Ensembl chr12:24,810,024...24,949,101 		JBrowse link
G BCKDK branched chain keto acid dehydrogenase kinase multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of BCKDK mRNA CTD PMID:20823114 NCBI chr16:31,108,386...31,117,640
Ensembl chr16:31,106,107...31,112,791 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
decreases expression		 EXP adenosine-3',5'-cyclic phosphorothioate inhibits the reaction [Bucladesine inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]]; Bucladesine inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]
Bucladesine results in decreased expression of BCL2 protein		 CTD PMID:10697531 PMID:16822680 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L13 BCL2 like 13 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of BCL2L13 mRNA CTD PMID:20823114 NCBI chr22:17,628,877...17,730,855
Ensembl chr22:17,628,855...17,730,855 		JBrowse link
G BDNF brain derived neurotrophic factor multiple interactions
increases expression		 EXP 1-bromopropane inhibits the reaction [Bucladesine results in increased expression of BDNF mRNA]; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of ENO2 mRNA; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of MAP2 mRNA; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of NEFL mRNA; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of NEFM mRNA CTD PMID:19189864 PMID:29698629 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G BET1L Bet1 golgi vesicular membrane trafficking protein like multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of BET1L mRNA CTD PMID:20823114 NCBI chr11:202,924...207,399
Ensembl chr11:167,784...207,399 		JBrowse link
G BICD1 BICD cargo adaptor 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of BICD1 mRNA CTD PMID:20823114 NCBI chr12:32,106,847...32,383,633
Ensembl chr12:32,106,835...32,383,633 		JBrowse link
G BMP4 bone morphogenetic protein 4 multiple interactions EXP Bucladesine inhibits the reaction [BMP4 protein results in increased expression of SMAD6 mRNA] CTD PMID:20522807 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761 		JBrowse link
G BSND barttin CLCNK type accessory subunit beta multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of BSND mRNA CTD PMID:20823114 NCBI chr 1:54,998,933...55,017,172
Ensembl chr 1:54,998,933...55,017,172 		JBrowse link
G C1R complement C1r multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of C1R mRNA CTD PMID:20823114 NCBI chr12:7,080,219...7,092,445
Ensembl chr12:7,080,214...7,092,540 		JBrowse link
G CALM1 calmodulin 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of CALM1 mRNA CTD PMID:20823114 NCBI chr14:90,396,502...90,408,268
Ensembl chr14:90,396,502...90,408,268 		JBrowse link
G CALR calreticulin increases stability ISO Bucladesine results in increased stability of CALR protein CTD PMID:9473613 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489 		JBrowse link
G CAPN2 calpain 2 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of CAPN2 mRNA CTD PMID:20823114 NCBI chr 1:223,701,597...223,776,018
Ensembl chr 1:223,701,593...223,776,018 		JBrowse link
G CASP3 caspase 3 multiple interactions EXP Bucladesine inhibits the reaction [CASP3 protein results in increased cleavage of RB1 protein]; Bucladesine promotes the reaction [Hydroxyurea results in increased activity of CASP3 protein] CTD PMID:10697531 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CAST calpastatin multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CAST mRNA CTD PMID:20823114 NCBI chr 5:95,961,429...96,774,683
Ensembl chr 5:96,525,267...96,779,595
Ensembl chr 5:96,525,267...96,779,595 		JBrowse link
G CAV2 caveolin 2 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of CAV2 mRNA CTD PMID:20823114 NCBI chr 7:116,499,738...116,508,541
Ensembl chr 7:116,287,380...116,508,541 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 multiple interactions EXP Bucladesine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CCL3 protein] CTD PMID:12538206 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G CCN2 cellular communication network factor 2 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CCN2 mRNA CTD PMID:20823114 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372 		JBrowse link
G CCNB1 cyclin B1 multiple interactions EXP [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression of CCNB1 mRNA; [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of CCNB1 protein CTD PMID:22534328 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245 		JBrowse link
G CCND1 cyclin D1 increases expression
multiple interactions		 ISO
EXP		 Bucladesine results in increased expression of CCND1 protein
[Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] affects the expression of CCND1 protein; [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in decreased expression of CCND1 mRNA; [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in decreased expression of CCND1 mRNA; [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in decreased expression of CCND1 protein		 CTD PMID:16718685 PMID:21693435 PMID:22534328 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CCND3 cyclin D3 increases expression ISO Bucladesine results in increased expression of CCND3 protein CTD PMID:16718685 NCBI chr 6:41,934,933...42,050,035
Ensembl chr 6:41,934,934...42,050,357 		JBrowse link
G CD69 CD69 molecule decreases expression ISO Bucladesine results in decreased expression of CD69 protein CTD PMID:25433234 NCBI chr12:9,752,486...9,760,901
Ensembl chr12:9,752,486...9,760,901 		JBrowse link
G CD80 CD80 molecule multiple interactions EXP Bucladesine inhibits the reaction [Lipopolysaccharides results in increased expression of CD80 protein] CTD PMID:12538815 NCBI chr 3:119,524,293...119,559,614
Ensembl chr 3:119,524,293...119,559,614 		JBrowse link
G CDC42BPA CDC42 binding protein kinase alpha multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of CDC42BPA mRNA CTD PMID:20823114 NCBI chr 1:226,989,858...227,318,492
Ensembl chr 1:226,989,865...227,318,492 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression
multiple interactions		 ISO
EXP		 Bucladesine results in increased expression of CDKN1A protein
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CDKN1A mRNA; [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression of CDKN1A mRNA; [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of CDKN1A protein
GJA1 promotes the reaction [Bucladesine results in increased expression of CDKN1A protein]		 CTD PMID:16718685 PMID:20823114 PMID:22534328 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B increases expression ISO Bucladesine results in increased expression of CDKN1B protein CTD PMID:16718685 PMID:21693435 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369 		JBrowse link
G CEBPB CCAAT enhancer binding protein beta increases expression
multiple interactions		 ISO Bucladesine results in increased expression of CEBPB protein
Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of CEBPB protein]		 CTD PMID:19282384 PMID:19698295 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668 		JBrowse link
G CEBPZ CCAAT enhancer binding protein zeta multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of CEBPZ mRNA CTD PMID:20823114 NCBI chr 2:37,201,612...37,231,596
Ensembl chr 2:37,201,612...37,231,596 		JBrowse link
G CHAT choline O-acetyltransferase multiple interactions
increases expression		 ISO [Bucladesine co-treated with Tretinoin] results in increased activity of CHAT protein; [Tretinoin co-treated with Bucladesine] results in increased activity of CHAT protein
Bucladesine results in increased expression of CHAT protein
Nicotine promotes the reaction [Bucladesine results in increased expression of CHAT protein]		 CTD PMID:16724269 PMID:20361958 PMID:29665406 NCBI chr10:49,609,095...49,667,942
Ensembl chr10:49,609,095...49,667,942 		JBrowse link
G CLDN5 claudin 5 increases expression ISO Bucladesine results in increased expression of CLDN5 mRNA CTD PMID:20711499 NCBI chr22:19,523,024...19,525,337
Ensembl chr22:19,523,024...19,527,545 		JBrowse link
G CNGB1 cyclic nucleotide gated channel subunit beta 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CNGB1 mRNA CTD PMID:20823114 NCBI chr16:57,882,340...57,971,128
Ensembl chr16:57,882,340...57,971,128 		JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions EXP Bucladesine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] CTD PMID:11576339 PMID:16430859 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632 		JBrowse link
G COL3A1 collagen type III alpha 1 chain multiple interactions EXP Bucladesine inhibits the reaction [TGFB1 protein results in increased expression of COL3A1 mRNA] CTD PMID:11576339 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746 		JBrowse link
G COL6A2 collagen type VI alpha 2 chain multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of COL6A2 mRNA CTD PMID:20823114 NCBI chr21:46,098,112...46,132,848
Ensembl chr21:46,098,112...46,132,848 		JBrowse link
G COL6A3 collagen type VI alpha 3 chain multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of COL6A3 mRNA CTD PMID:20823114 NCBI chr 2:237,324,018...237,414,164
Ensembl chr 2:237,324,003...237,414,328 		JBrowse link
G COX6A2 cytochrome c oxidase subunit 6A2 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of COX6A2 mRNA CTD PMID:20823114 NCBI chr16:31,427,731...31,428,360
Ensembl chr16:31,427,731...31,428,360 		JBrowse link
G CPLX1 complexin 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CPLX1 mRNA CTD PMID:20823114 NCBI chr 4:784,957...826,129
Ensembl chr 4:784,957...826,129 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 increases phosphorylation
multiple interactions		 ISO
EXP		 Bucladesine results in increased phosphorylation of CREB1 protein
[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the phosphorylation of CREB1 protein; [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREB1 protein binds to NR4A1 promoter]; Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [Dinoprostone results in increased phosphorylation of CREB1 protein]]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the phosphorylation of CREB1 protein]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREB1 protein binds to NR4A1 promoter]]
[Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]] promotes the reaction [CREBBP protein binds to STAR promoter]; bisindolylmaleimide I inhibits the reaction [Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]; CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; CREBBP protein promotes the reaction [CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of CREB1 protein]		 CTD PMID:12164941 PMID:18787026 PMID:19282384 PMID:36565944 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988 		JBrowse link
G CREBBP CREB binding protein multiple interactions EXP
ISO		 [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREBBP protein binds to NR4A1 promoter]; Bucladesine promotes the reaction [CREBBP protein binds to SOD2 promoter]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREBBP protein binds to NR4A1 promoter]]
[Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]] promotes the reaction [CREBBP protein binds to STAR promoter]; CREBBP protein promotes the reaction [CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]]		 CTD PMID:19282384 PMID:20685861 PMID:36565944 NCBI chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713 		JBrowse link
G CREM cAMP responsive element modulator multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of CREM mRNA CTD PMID:20823114 NCBI chr10:35,126,846...35,212,958
Ensembl chr10:35,126,791...35,212,958 		JBrowse link
G CRYAB crystallin alpha B multiple interactions ISO Bucladesine inhibits the reaction [arsenite results in increased expression of CRYAB protein] CTD PMID:8769853 NCBI chr11:111,908,564...111,923,740
Ensembl chr11:111,908,564...111,923,722 		JBrowse link
G CSF1R colony stimulating factor 1 receptor multiple interactions EXP Bucladesine promotes the reaction [Tretinoin results in increased expression of CSF1R mRNA] CTD PMID:8445950 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372 		JBrowse link
G CTBP1 C-terminal binding protein 1 multiple interactions
affects localization		 EXP Bucladesine inhibits the reaction [CTBP1 protein binds to KAT2A protein]; Bucladesine inhibits the reaction [CTBP1 protein binds to NR5A1 protein]; Bucladesine promotes the reaction [CTBP1 protein binds to CTBP2 protein]
Bucladesine affects the localization of CTBP1 protein		 CTD PMID:18184656 NCBI chr 4:1,211,445...1,250,355
Ensembl chr 4:1,211,445...1,250,333 		JBrowse link
G CTBP2 C-terminal binding protein 2 affects localization
multiple interactions		 EXP Bucladesine affects the localization of CTBP2 protein
Bucladesine promotes the reaction [CTBP1 protein binds to CTBP2 protein]		 CTD PMID:18184656 NCBI chr10:124,984,317...125,162,463
Ensembl chr10:124,984,317...125,161,170 		JBrowse link
G CTNNB1 catenin beta 1 increases phosphorylation ISO Bucladesine results in increased phosphorylation of CTNNB1 protein CTD PMID:26964897 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G CTPS2 CTP synthase 2 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of CTPS2 mRNA CTD PMID:20823114 NCBI chr  X:16,587,999...16,712,910
Ensembl chr  X:16,587,999...16,712,936 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 decreases expression ISO Bucladesine results in decreased expression of CXCL12 mRNA CTD PMID:20711499 NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP Bucladesine promotes the reaction [Lipopolysaccharides results in increased expression of CXCL8 protein] CTD PMID:9258252 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYB5D1 cytochrome b5 domain containing 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CYB5D1 mRNA CTD PMID:20823114 NCBI chr17:7,858,003...7,862,282
Ensembl chr17:7,857,746...7,862,282 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 increases expression
multiple interactions		 ISO
EXP		 Bucladesine results in increased expression of CYP11A1 mRNA
fluorene-9-bisphenol inhibits the reaction [Bucladesine results in increased expression of CYP11A1 mRNA]
[Atrazine co-treated with Bucladesine] results in increased expression of CYP11A1 mRNA; Atrazine inhibits the reaction [Bucladesine results in increased expression of CYP11A1 mRNA]; Quercetin inhibits the reaction [[Atrazine co-treated with Bucladesine] results in increased expression of CYP11A1 mRNA]		 CTD PMID:21693180 PMID:21979172 PMID:23200735 PMID:35987080 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646 		JBrowse link
G CYP11B1 cytochrome P450 family 11 subfamily B member 1 increases expression
multiple interactions		 EXP Bucladesine results in increased expression of CYP11B1 mRNA
fluorene-9-bisphenol inhibits the reaction [Bucladesine results in increased expression of CYP11B1 mRNA]		 CTD PMID:35987080 NCBI chr 8:142,872,357...142,879,825
Ensembl chr 8:142,872,356...142,879,846 		JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 increases expression
multiple interactions		 EXP Bucladesine results in increased expression of CYP11B2 mRNA
fluorene-9-bisphenol affects the reaction [Bucladesine results in increased expression of CYP11B2 mRNA]		 CTD PMID:35987080 NCBI chr 8:142,910,559...142,917,843
Ensembl chr 8:142,910,559...142,917,843 		JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 decreases expression
multiple interactions
increases expression		 ISO
EXP		 Bucladesine results in decreased expression of CYP17A1 mRNA
fluorene-9-bisphenol inhibits the reaction [Bucladesine results in increased expression of CYP17A1 mRNA]
[Atrazine co-treated with Bucladesine] results in increased expression of CYP17A1 mRNA; Quercetin inhibits the reaction [[Atrazine co-treated with Bucladesine] results in increased expression of CYP17A1 mRNA]		 CTD PMID:21458522 PMID:21693180 PMID:23200735 PMID:35987080 NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472 		JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 increases expression
multiple interactions		 EXP Bucladesine results in increased expression of CYP19A1 mRNA
fluorene-9-bisphenol inhibits the reaction [Bucladesine results in increased expression of CYP19A1 mRNA]		 CTD PMID:35987080 NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions ISO Bucladesine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Bucladesine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Bucladesine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]
Bucladesine affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]		 CTD PMID:1849469 PMID:16901605 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 multiple interactions ISO Bucladesine affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA] CTD PMID:1849469 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 increases expression ISO Bucladesine results in increased expression of CYP1B1 mRNA CTD PMID:11559018 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G CYP21A2 cytochrome P450 family 21 subfamily A member 2 increases expression
multiple interactions		 EXP Bucladesine results in increased expression of CYP21A2 mRNA
fluorene-9-bisphenol inhibits the reaction [Bucladesine results in increased expression of CYP21A2 mRNA]		 CTD PMID:35987080 NCBI chr 6:32,038,415...32,041,644
Ensembl chr 6:32,038,327...32,041,644 		JBrowse link
G CYP2A6 cytochrome P450 family 2 subfamily A member 6 multiple interactions
increases expression		 ISO NFE2L2 gene mutant form promotes the reaction [Bucladesine results in increased expression of CYP2A5 mRNA] CTD PMID:11162586 PMID:22859313 NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 multiple interactions EXP Bucladesine promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol] CTD PMID:8531136 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G DCN decorin multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of DCN protein; Azacitidine promotes the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of DCN protein] CTD PMID:20823114 NCBI chr12:91,140,484...91,182,817
Ensembl chr12:91,140,484...91,183,217 		JBrowse link
G DDX27 DEAD-box helicase 27 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of DDX27 mRNA CTD PMID:20823114 NCBI chr20:49,219,416...49,244,073
Ensembl chr20:49,219,347...49,244,077 		JBrowse link
G DES desmin multiple interactions ISO
EXP		 [Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of DES mRNA
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of DES mRNA		 CTD PMID:19089455 PMID:20823114 NCBI chr 2:219,418,377...219,426,734
Ensembl chr 2:219,418,377...219,426,735 		JBrowse link
G DHX9 DExH-box helicase 9 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of DHX9 mRNA CTD PMID:20823114 NCBI chr 1:182,839,347...182,887,982
Ensembl chr 1:182,839,347...182,887,982 		JBrowse link
G DIO2 iodothyronine deiodinase 2 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of DIO2 mRNA CTD PMID:20823114 NCBI chr14:80,197,526...80,231,057
Ensembl chr14:80,197,526...80,387,757 		JBrowse link
G DTYMK deoxythymidylate kinase multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of DTYMK mRNA CTD PMID:20823114 NCBI chr 2:241,675,747...241,686,815
Ensembl chr 2:241,675,747...241,686,944 		JBrowse link
G EDA ectodysplasin A multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of EDA mRNA CTD PMID:20823114 NCBI chr  X:69,616,113...70,039,472
Ensembl chr  X:69,616,067...70,039,472 		JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of EEF1A1 mRNA CTD PMID:20823114 NCBI chr 6:73,515,750...73,521,032
Ensembl chr 6:73,489,308...73,525,587 		JBrowse link
G EFEMP1 EGF containing fibulin extracellular matrix protein 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of EFEMP1 mRNA CTD PMID:20823114 NCBI chr 2:55,865,967...55,923,782
Ensembl chr 2:55,865,967...55,924,139 		JBrowse link
G EGF epidermal growth factor multiple interactions EXP [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of ENO2 mRNA; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of MAP2 mRNA; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of NEFL mRNA; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of NEFM mRNA CTD PMID:29698629 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G EGR2 early growth response 2 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of EGR2 mRNA CTD PMID:20823114 NCBI chr10:62,811,996...62,819,167
Ensembl chr10:62,811,996...62,819,167 		JBrowse link
G EIF3LP3 eukaryotic translation initiation factor 3 subunit L pseudogene 3 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of EIF3LP3 mRNA CTD PMID:20823114 NCBI chr10:38,079,901...38,080,863
Ensembl chr10:38,080,056...38,080,877 		JBrowse link
G ENO2 enolase 2 multiple interactions EXP [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of ENO2 mRNA CTD PMID:29698629 NCBI chr12:6,914,580...6,923,697
Ensembl chr12:6,913,745...6,923,698 		JBrowse link
G EPB41L4A erythrocyte membrane protein band 4.1 like 4A multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of EPB41L4A mRNA CTD PMID:20823114 NCBI chr 5:112,141,829...112,419,935
Ensembl chr 5:112,142,441...112,419,313 		JBrowse link
G EPHA3 EPH receptor A3 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of EPHA3 mRNA CTD PMID:20823114 NCBI chr 3:89,107,621...89,482,134
Ensembl chr 3:89,107,621...89,482,134 		JBrowse link
G ESR1 estrogen receptor 1 increases expression
multiple interactions		 ISO Bucladesine results in increased expression of ESR1 mRNA
[Quercetin co-treated with Bucladesine] results in increased expression of ESR1 mRNA; Atrazine inhibits the reaction [Bucladesine results in increased expression of ESR1 mRNA]		 CTD PMID:21693180 PMID:23200735 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G EYA1 EYA transcriptional coactivator and phosphatase 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of EYA1 mRNA CTD PMID:20823114 NCBI chr 8:71,197,433...71,548,094
Ensembl chr 8:71,197,433...71,592,025 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit multiple interactions EXP [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [EZH2 protein binds to NR4A1 promoter]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [EZH2 protein binds to NR4A1 promoter]] CTD PMID:36565944 NCBI chr 7:148,807,383...148,884,291
Ensembl chr 7:148,807,257...148,884,321 		JBrowse link
G FADS2 fatty acid desaturase 2 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of FADS2 mRNA CTD PMID:20823114 NCBI chr11:61,816,203...61,867,354
Ensembl chr11:61,792,980...61,867,354 		JBrowse link
G FAS Fas cell surface death receptor increases expression
multiple interactions		 ISO Bucladesine results in increased expression of FAS mRNA
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of FAS mRNA]		 CTD PMID:12414803 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FBXO11 F-box protein 11 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of FBXO11 mRNA CTD PMID:20823114 NCBI chr 2:47,806,920...47,906,498
Ensembl chr 2:47,789,316...47,906,498 		JBrowse link
G FBXW5 F-box and WD repeat domain containing 5 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of FBXW5 mRNA CTD PMID:20823114 NCBI chr 9:136,940,435...136,944,738
Ensembl chr 9:136,940,435...136,944,738 		JBrowse link
G FCER2 Fc epsilon receptor II decreases expression ISO Bucladesine results in decreased expression of FCER2 protein CTD PMID:1328389 NCBI chr19:7,688,776...7,702,131
Ensembl chr19:7,688,758...7,702,146 		JBrowse link
G FGD1 FYVE, RhoGEF and PH domain containing 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of FGD1 mRNA CTD PMID:20823114 NCBI chr  X:54,445,454...54,496,234
Ensembl chr  X:54,445,454...54,496,234 		JBrowse link
G FGF2 fibroblast growth factor 2 multiple interactions EXP [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of ENO2 mRNA; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of MAP2 mRNA; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of NEFL mRNA; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of NEFM mRNA CTD PMID:29698629 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236 		JBrowse link
G FGF9 fibroblast growth factor 9 multiple interactions EXP FGF9 protein inhibits the reaction [Bucladesine promotes the reaction [IGF1 protein results in increased abundance of Estradiol]]; FGF9 protein inhibits the reaction [IGF1 protein promotes the reaction [Bucladesine results in increased abundance of Progesterone]]; FGF9 protein promotes the reaction [Bucladesine results in increased abundance of Progesterone] CTD PMID:22798350 NCBI chr13:21,671,073...21,704,498
Ensembl chr13:21,671,073...21,704,498 		JBrowse link
G FILIP1L filamin A interacting protein 1 like multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of FILIP1L mRNA CTD PMID:20823114 NCBI chr 3:99,828,811...100,114,501
Ensembl chr 3:99,828,811...100,114,513 		JBrowse link
G FKBP5 FKBP prolyl isomerase 5 multiple interactions ISO [bisphenol A co-treated with Bucladesine] results in increased methylation of FKBP5 intron; [Bucladesine co-treated with bisphenol A] results in decreased expression of FKBP5 mRNA; [Bucladesine co-treated with bisphenol A] results in decreased expression of FKBP5 protein; [Bucladesine co-treated with Dexamethasone] results in increased expression of FKBP5 mRNA; [Bucladesine co-treated with fulvestrant] results in decreased expression of FKBP5 mRNA; [Bucladesine co-treated with fulvestrant] results in decreased expression of FKBP5 protein; [fulvestrant co-treated with Bucladesine] results in increased methylation of FKBP5 intron; bisphenol A promotes the reaction [[fulvestrant co-treated with Bucladesine] results in increased methylation of FKBP5 intron]; Dexamethasone inhibits the reaction [[Bucladesine co-treated with bisphenol A] results in decreased expression of FKBP5 mRNA]; Estradiol inhibits the reaction [[Bucladesine co-treated with fulvestrant] results in decreased expression of FKBP5 mRNA] CTD PMID:26427651 NCBI chr 6:35,573,590...35,728,583
Ensembl chr 6:35,573,585...35,728,583 		JBrowse link
G FN1 fibronectin 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of FN1 mRNA CTD PMID:20823114 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit affects expression
multiple interactions
increases expression		 EXP
ISO		 Bucladesine affects the expression of FOS protein
Bucladesine results in increased expression of and results in increased phosphorylation of FOS protein; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of FOS protein]
Bucladesine results in increased expression of FOS mRNA; Bucladesine results in increased expression of FOS protein		 CTD PMID:7798212 PMID:9187264 PMID:19282384 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G FOXO1 forkhead box O1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of FOXO1 mRNA; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of FOXO1 mRNA; [Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of and results in increased localization of FOXO1 protein; AGT protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of and results in increased localization of FOXO1 protein] CTD PMID:20823114 PMID:36682589 NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641 		JBrowse link
G FSCN2 fascin actin-bundling protein 2, retinal multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of FSCN2 mRNA CTD PMID:20823114 NCBI chr17:81,515,062...81,537,130
Ensembl chr17:81,528,377...81,537,130 		JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 increases expression
multiple interactions		 ISO Bucladesine results in increased expression of G6PC1 mRNA; Bucladesine results in increased expression of G6PC1 protein
IL22 protein inhibits the reaction [Bucladesine results in increased expression of G6PC1 protein]; NFE2L2 gene mutant form promotes the reaction [Bucladesine results in increased expression of G6PC1 mRNA]; STAT3 gene mutant form affects the reaction [IL22 protein inhibits the reaction [Bucladesine results in increased expression of G6PC1 protein]]		 CTD PMID:22859313 PMID:26064446 NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438 		JBrowse link
G GARS1 glycyl-tRNA synthetase 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of GARS1 mRNA CTD PMID:20823114 NCBI chr 7:30,594,735...30,634,033
Ensembl chr 7:30,580,533...30,634,033 		JBrowse link
G GBE1 1,4-alpha-glucan branching enzyme 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of GBE1 mRNA CTD PMID:20823114 NCBI chr 3:81,489,703...81,761,645
Ensembl chr 3:81,489,703...81,761,645 		JBrowse link
G GBP2 guanylate binding protein 2 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of GBP2 mRNA CTD PMID:20823114 NCBI chr 1:89,106,132...89,126,114
Ensembl chr 1:89,106,132...89,150,456 		JBrowse link
G GCNT2 glucosaminyl (N-acetyl) transferase 2 (I blood group) multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of GCNT2 mRNA CTD PMID:20823114 NCBI chr 6:10,521,351...10,629,368
Ensembl chr 6:10,492,223...10,629,368 		JBrowse link
G GDF3 growth differentiation factor 3 affects expression
multiple interactions		 EXP Bucladesine affects the expression of GDF3 mRNA; Bucladesine affects the expression of GDF3 protein
bisphenol A affects the reaction [Bucladesine affects the expression of GDF3 mRNA]; bisphenol A affects the reaction [Bucladesine affects the expression of GDF3 protein]; Methylmercury Compounds affects the reaction [Bucladesine affects the expression of GDF3 mRNA]; Methylmercury Compounds affects the reaction [Bucladesine affects the expression of GDF3 protein]; Paraquat affects the reaction [Bucladesine affects the expression of GDF3 mRNA]; Paraquat affects the reaction [Bucladesine affects the expression of GDF3 protein]		 CTD PMID:31400064 NCBI chr12:7,689,784...7,695,775
Ensembl chr12:7,689,784...7,695,775 		JBrowse link
G GDNF glial cell derived neurotrophic factor multiple interactions EXP [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the expression of NR4A1 mRNA; [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the expression of NR4A1 protein; [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the methylation of NR4A1 promoter; [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the phosphorylation of CREB1 protein; [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREB1 protein binds to NR4A1 promoter]; [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREBBP protein binds to NR4A1 promoter]; [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [EZH2 protein binds to NR4A1 promoter]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the expression of NR4A1 mRNA]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the expression of NR4A1 protein]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the methylation of NR4A1 promoter]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the phosphorylation of CREB1 protein]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREB1 protein binds to NR4A1 promoter]]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREBBP protein binds to NR4A1 promoter]]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [EZH2 protein binds to NR4A1 promoter]] CTD PMID:36565944 NCBI chr 5:37,812,677...37,840,041
Ensembl chr 5:37,812,677...37,840,041 		JBrowse link
G GIPC1 GIPC PDZ domain containing family member 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of GIPC1 mRNA CTD PMID:20823114 NCBI chr19:14,477,762...14,496,127
Ensembl chr19:14,477,760...14,496,149 		JBrowse link
G GJA1 gap junction protein alpha 1 multiple interactions
increases expression		 ISO GJA1 promotes the reaction [Bucladesine results in increased expression of CDKN1A protein]; Tolbutamide promotes the reaction [Bucladesine results in increased expression of GJA1 protein] CTD PMID:11741589 PMID:16718685 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727 		JBrowse link
G GPD1 glycerol-3-phosphate dehydrogenase 1 multiple interactions ISO Bucladesine promotes the reaction [Bezafibrate results in increased expression of GPD1 mRNA] CTD PMID:1976021 NCBI chr12:50,104,008...50,111,313
Ensembl chr12:50,103,982...50,111,313 		JBrowse link
G GPKOW G-patch domain and KOW motifs multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of GPKOW mRNA CTD PMID:20823114 NCBI chr  X:49,113,407...49,123,735
Ensembl chr  X:49,113,407...49,123,735 		JBrowse link
G GPNMB glycoprotein nmb multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of GPNMB mRNA CTD PMID:20823114 NCBI chr 7:23,246,775...23,275,108
Ensembl chr 7:23,235,967...23,275,108 		JBrowse link
G GSTA1 glutathione S-transferase alpha 1 multiple interactions
increases expression		 EXP KT 5720 inhibits the reaction [Bucladesine results in increased expression of GSTA1 mRNA] CTD PMID:26049102 NCBI chr 6:52,791,371...52,803,816
Ensembl chr 6:52,791,371...52,803,860 		JBrowse link
G GSTA2 glutathione S-transferase alpha 2 increases expression
multiple interactions		 EXP Bucladesine results in increased expression of GSTA2 mRNA
KT 5720 inhibits the reaction [Bucladesine results in increased expression of GSTA2 mRNA]		 CTD PMID:26049102 NCBI chr 6:52,750,087...52,763,475
Ensembl chr 6:52,750,087...52,763,475 		JBrowse link
G GSTA3 glutathione S-transferase alpha 3 increases expression
multiple interactions		 EXP Bucladesine results in increased expression of GSTA3 mRNA
KT 5720 inhibits the reaction [Bucladesine results in increased expression of GSTA3 mRNA]		 CTD PMID:26049102 NCBI chr 6:52,896,646...52,909,698
Ensembl chr 6:52,896,639...52,909,698 		JBrowse link
G GSTA4 glutathione S-transferase alpha 4 increases expression
multiple interactions		 EXP Bucladesine results in increased expression of GSTA4 mRNA
KT 5720 inhibits the reaction [Bucladesine results in increased expression of GSTA4 mRNA]		 CTD PMID:26049102 NCBI chr 6:52,977,953...52,995,284
Ensembl chr 6:52,977,948...52,995,304 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha increases expression EXP Bucladesine results in increased expression of HIF1A mRNA CTD PMID:18591213 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases expression		 EXP fluorene-9-bisphenol inhibits the reaction [Bucladesine results in increased expression of HMGCR mRNA] CTD PMID:35987080 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G HOXA1 homeobox A1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of HOXA1 mRNA; Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of HOXA1 mRNA] CTD PMID:20823114 NCBI chr 7:27,092,993...27,096,000
Ensembl chr 7:27,092,993...27,096,000 		JBrowse link
G HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 decreases expression
multiple interactions		 EXP Bucladesine results in decreased expression of HSD17B1 mRNA
fluorene-9-bisphenol inhibits the reaction [Bucladesine results in decreased expression of HSD17B1 mRNA]		 CTD PMID:35987080 NCBI chr17:42,552,923...42,555,214
Ensembl chr17:42,552,922...42,555,214 		JBrowse link
G HSD17B12 hydroxysteroid 17-beta dehydrogenase 12 increases expression ISO Bucladesine results in increased expression of HSD17B12 mRNA CTD PMID:21458522 NCBI chr11:43,556,721...43,856,615
Ensembl chr11:43,680,680...43,856,617 		JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 increases expression ISO Bucladesine results in increased expression of HSD3B1 mRNA CTD PMID:21458522 NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054 		JBrowse link
G HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 increases expression
multiple interactions		 EXP Bucladesine results in increased expression of HSD3B2 mRNA
fluorene-9-bisphenol inhibits the reaction [Bucladesine results in increased expression of HSD3B2 mRNA]		 CTD PMID:35987080 NCBI chr 1:119,414,931...119,423,034
Ensembl chr 1:119,414,931...119,423,035 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 increases expression
increases phosphorylation		 ISO
EXP		 Bucladesine results in increased expression of HSP27 protein
Bucladesine results in increased phosphorylation of HSPB1 protein		 CTD PMID:7541446 PMID:10559386 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of HTR1A mRNA CTD PMID:20823114 NCBI chr 5:63,957,874...63,962,445
Ensembl chr 5:63,957,874...63,962,507 		JBrowse link
G IAPP islet amyloid polypeptide increases expression ISO Bucladesine results in increased expression of IAPP mRNA CTD PMID:9142872 NCBI chr12:21,354,959...21,379,980
Ensembl chr12:21,354,959...21,379,980 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions EXP Bucladesine inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein] CTD PMID:12538815 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G ID1 inhibitor of DNA binding 1 increases expression
multiple interactions		 EXP Bucladesine results in increased expression of ID1 protein
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of ID1 mRNA]		 CTD PMID:20522807 NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,605,283...31,606,515 		JBrowse link
G IFRD2 interferon related developmental regulator 2 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IFRD2 mRNA CTD PMID:20823114 NCBI chr 3:50,287,732...50,292,429
Ensembl chr 3:50,287,732...50,292,918 		JBrowse link
G IGF1 insulin like growth factor 1 multiple interactions EXP Bucladesine promotes the reaction [IGF1 protein results in increased abundance of Estradiol]; FGF9 protein inhibits the reaction [Bucladesine promotes the reaction [IGF1 protein results in increased abundance of Estradiol]]; FGF9 protein inhibits the reaction [IGF1 protein promotes the reaction [Bucladesine results in increased abundance of Progesterone]]; IGF1 protein promotes the reaction [Bucladesine results in increased abundance of Progesterone] CTD PMID:22798350 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 increases expression
multiple interactions		 EXP Bucladesine results in increased expression of IGFBP1
[Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 mRNA; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 mRNA; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 protein; Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 mRNA]; Azacitidine promotes the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 protein]		 CTD PMID:12093828 PMID:20823114 PMID:30328349 NCBI chr 7:45,888,488...45,893,660
Ensembl chr 7:45,888,360...45,893,660 		JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP3 mRNA CTD PMID:20823114 NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874 		JBrowse link
G IGFBP4 insulin like growth factor binding protein 4 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP4 mRNA CTD PMID:20823114 NCBI chr17:40,443,450...40,457,725
Ensembl chr17:40,443,450...40,457,725 		JBrowse link
G IGHE immunoglobulin heavy constant epsilon multiple interactions EXP Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [IL4 protein results in increased expression of IGHE mRNA alternative form]]; Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [IL4 protein results in increased expression of IGHE mRNA]] CTD PMID:12230500 NCBI chr14:105,600,066...105,601,727
Ensembl chr14:105,597,691...105,601,728 		JBrowse link
G IL10 interleukin 10 decreases expression
multiple interactions		 EXP
ISO		 Bucladesine results in decreased expression of IL10
Bucladesine promotes the reaction [Zymosan results in increased expression of IL10 protein]		 CTD PMID:11301049 PMID:19273625 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL12B interleukin 12B multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IL12B mRNA CTD PMID:20823114 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G IL13 interleukin 13 decreases expression
decreases secretion		 EXP Bucladesine results in decreased expression of IL13 mRNA
Bucladesine results in decreased secretion of IL13 protein		 CTD PMID:16083514 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL1B interleukin 1 beta multiple interactions EXP Bucladesine promotes the reaction [IL1B protein results in increased abundance of Nitrites]; Dipyridamole promotes the reaction [Bucladesine promotes the reaction [IL1B protein results in increased abundance of Nitrites]] CTD PMID:8904084 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL22 interleukin 22 multiple interactions ISO dorsomorphin affects the reaction [IL22 protein inhibits the reaction [Bucladesine results in increased abundance of Glucose]]; IL22 protein inhibits the reaction [Bucladesine results in increased abundance of Glucose]; IL22 protein inhibits the reaction [Bucladesine results in increased expression of G6PC1 protein]; IL22 protein inhibits the reaction [Bucladesine results in increased expression of PPARGC1A protein]; STAT3 gene mutant form affects the reaction [IL22 protein inhibits the reaction [Bucladesine results in increased expression of G6PC1 protein]] CTD PMID:26064446 NCBI chr12:68,248,242...68,253,604
Ensembl chr12:68,248,242...68,253,604 		JBrowse link
G IL23A interleukin 23 subunit alpha increases expression
multiple interactions		 EXP Bucladesine results in increased expression of IL23A mRNA
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of IL23A mRNA		 CTD PMID:19273625 PMID:20823114 NCBI chr12:56,338,884...56,340,410
Ensembl chr12:56,334,174...56,340,410 		JBrowse link
G IL2RA interleukin 2 receptor subunit alpha decreases expression EXP
ISO		 Bucladesine results in decreased expression of IL2RA protein CTD PMID:1709825 PMID:25433234 NCBI chr10:6,010,689...6,062,367
Ensembl chr10:6,010,689...6,062,370 		JBrowse link
G IL4 interleukin 4 multiple interactions EXP Bucladesine inhibits the reaction [Itraconazole results in decreased expression of IL4 mRNA]; Bucladesine inhibits the reaction [Itraconazole results in decreased secretion of IL4 protein]; Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [IL4 protein results in increased expression of IGHE mRNA alternative form]]; Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [IL4 protein results in increased expression of IGHE mRNA]]; Bucladesine inhibits the reaction [Ketoconazole results in decreased expression of IL4 mRNA]; Bucladesine inhibits the reaction [Ketoconazole results in decreased secretion of IL4 protein]; Bucladesine inhibits the reaction [Miconazole results in decreased expression of IL4 mRNA]; Bucladesine inhibits the reaction [Miconazole results in decreased secretion of IL4 protein]; Bucladesine inhibits the reaction [terbinafine results in decreased expression of IL4 mRNA]; Bucladesine inhibits the reaction [terbinafine results in decreased secretion of IL4 protein]; Bucladesine inhibits the reaction [Tolnaftate results in decreased expression of IL4 mRNA]; Bucladesine inhibits the reaction [Tolnaftate results in decreased secretion of IL4 protein] CTD PMID:11886533 PMID:12230500 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL5 interleukin 5 multiple interactions EXP Bucladesine inhibits the reaction [Itraconazole results in decreased expression of IL5 mRNA]; Bucladesine inhibits the reaction [Itraconazole results in decreased secretion of IL5 protein]; Bucladesine inhibits the reaction [Ketoconazole results in decreased expression of IL5 mRNA]; Bucladesine inhibits the reaction [Ketoconazole results in decreased secretion of IL5 protein]; Bucladesine inhibits the reaction [Miconazole results in decreased expression of IL5 mRNA]; Bucladesine inhibits the reaction [Miconazole results in decreased secretion of IL5 protein]; Bucladesine inhibits the reaction [terbinafine results in decreased expression of IL5 mRNA]; Bucladesine inhibits the reaction [terbinafine results in decreased secretion of IL5 protein]; Bucladesine inhibits the reaction [Tolnaftate results in decreased expression of IL5 mRNA]; Bucladesine inhibits the reaction [Tolnaftate results in decreased secretion of IL5 protein] CTD PMID:11886533 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838 		JBrowse link
G IL6 interleukin 6 multiple interactions EXP [Bucladesine co-treated with Theophylline] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Bucladesine promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Bucladesine promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:20388727 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INHA inhibin subunit alpha decreases expression
multiple interactions		 ISO Bucladesine results in decreased expression of INHA mRNA
[Atrazine co-treated with Bucladesine] results in increased expression of INHA mRNA; Atrazine inhibits the reaction [Bucladesine results in decreased expression of INHA mRNA]; Quercetin inhibits the reaction [[Atrazine co-treated with Bucladesine] results in increased expression of INHA mRNA]		 CTD PMID:21693180 PMID:23200735 NCBI chr 2:219,572,310...219,575,711
Ensembl chr 2:219,569,162...219,575,711 		JBrowse link
G INSL3 insulin like 3 multiple interactions
increases expression		 ISO [Atrazine co-treated with Bucladesine] results in increased expression of INSL3 mRNA; Atrazine inhibits the reaction [Bucladesine results in increased expression of INSL3 mRNA]; Quercetin inhibits the reaction [[Atrazine co-treated with Bucladesine] results in increased expression of INSL3 mRNA] CTD PMID:21458522 PMID:21693180 PMID:23200735 NCBI chr19:17,816,512...17,821,519
Ensembl chr19:17,816,512...17,821,574 		JBrowse link
G INTS7 integrator complex subunit 7 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of INTS7 mRNA CTD PMID:20823114 NCBI chr 1:211,940,403...212,035,557
Ensembl chr 1:211,940,399...212,035,557 		JBrowse link
G IRF9 interferon regulatory factor 9 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IRF9 mRNA CTD PMID:20823114 NCBI chr14:24,161,265...24,166,565
Ensembl chr14:24,161,234...24,168,043 		JBrowse link
G ISG20L2 interferon stimulated exonuclease gene 20 like 2 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ISG20L2 mRNA CTD PMID:20823114 NCBI chr 1:156,721,891...156,728,766
Ensembl chr 1:156,721,891...156,728,766 		JBrowse link
G ITGB1 integrin subunit beta 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ITGB1 mRNA CTD PMID:20823114 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792 		JBrowse link
G ITIH5 inter-alpha-trypsin inhibitor heavy chain 5 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ITIH5 mRNA CTD PMID:20823114 NCBI chr10:7,559,270...7,666,966
Ensembl chr10:7,559,270...7,666,998 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions		 ISO
EXP		 Bucladesine results in increased expression of JUN mRNA; Bucladesine results in increased expression of JUN protein
Bucladesine results in increased expression of JUN protein; Bucladesine results in increased expression of JUN protein modified form
Bucladesine promotes the reaction [JUN protein binds to ABCC2 promoter]; Bucladesine promotes the reaction [JUN protein binds to ATF2 protein]; KT 5720 inhibits the reaction [Bucladesine results in increased expression of JUN protein modified form]; KT 5720 inhibits the reaction [Bucladesine results in increased expression of JUN protein]
[Bucladesine co-treated with ciglitazone] results in increased expression of and results in increased phosphorylation of JUN protein; [ciglitazone co-treated with Bucladesine] promotes the reaction [JUN protein results in increased expression of STAR mRNA]; Bucladesine promotes the reaction [ciglitazone results in increased expression of JUN mRNA]; Bucladesine results in increased expression of and results in increased phosphorylation of JUN protein; ciglitazone promotes the reaction [Bucladesine results in increased expression of JUN mRNA]; GFX 109203x inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of JUN protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of JUN protein]]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of JUN protein]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of JUN protein]		 CTD PMID:9187264 PMID:18755854 PMID:19282384 PMID:19698295 PMID:26049102 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G KAT2A lysine acetyltransferase 2A multiple interactions EXP Bucladesine inhibits the reaction [CTBP1 protein binds to KAT2A protein] CTD PMID:18184656 NCBI chr17:42,113,111...42,121,367
Ensembl chr17:42,113,111...42,121,367 		JBrowse link
G KCNC4 potassium voltage-gated channel subfamily C member 4 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KCNC4 mRNA CTD PMID:20823114 NCBI chr 1:110,210,314...110,284,080
Ensembl chr 1:110,210,314...110,283,100 		JBrowse link
G KNG1 kininogen 1 increases activity ISO Bucladesine results in increased activity of KNG1 CTD PMID:1334751 NCBI chr 3:186,717,359...186,744,410
Ensembl chr 3:186,717,348...186,744,410 		JBrowse link
G KRT8 keratin 8 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KRT8 mRNA; Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KRT8 mRNA] CTD PMID:20823114 NCBI chr12:52,897,191...52,949,860
Ensembl chr12:52,897,187...52,949,954 		JBrowse link
G LAMB2 laminin subunit beta 2 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of LAMB2 mRNA CTD PMID:20823114 NCBI chr 3:49,121,114...49,133,050
Ensembl chr 3:49,121,114...49,133,118 		JBrowse link
G LDHA lactate dehydrogenase A multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of LDHA mRNA CTD PMID:20823114 NCBI chr11:18,394,563...18,408,425
Ensembl chr11:18,394,560...18,408,425 		JBrowse link
G LEP leptin decreases expression ISO Bucladesine results in decreased expression of LEP mRNA CTD PMID:9002984 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G LGALS3 galectin 3 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of LGALS3 mRNA CTD PMID:20823114 NCBI chr14:55,129,252...55,145,430
Ensembl chr14:55,124,110...55,145,423 		JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor decreases expression
multiple interactions		 ISO Bucladesine results in decreased expression of LHCGR mRNA
[Atrazine co-treated with Bucladesine] results in increased expression of LHCGR mRNA; Quercetin inhibits the reaction [[Atrazine co-treated with Bucladesine] results in increased expression of LHCGR mRNA]		 CTD PMID:21693180 PMID:23200735 NCBI chr 2:48,686,774...48,755,724
Ensembl chr 2:48,686,774...48,755,730 		JBrowse link
G LIPE lipase E, hormone sensitive type affects localization
increases activity
increases expression
multiple interactions		 ISO Bucladesine affects the localization of LIPE protein
Bucladesine results in increased activity of LIPE protein
Bucladesine results in increased expression of LIPE mRNA
[Bucladesine co-treated with LIPE protein] results in increased expression of ABCA1 protein; [Bucladesine co-treated with LIPE protein] results in increased expression of and results in increased phosphorylation of STAR protein; Bucladesine results in increased expression of and results in increased phosphorylation of LIPE protein; CAY 10499 inhibits the reaction [Bucladesine results in increased activity of and results in increased phosphorylation of LIPE protein]; LIPE protein affects the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]; LIPE protein affects the reaction [Bucladesine results in increased expression of PLIN1 mRNA]; LIPE protein affects the reaction [Bucladesine results in increased expression of SCARB1 mRNA]; LIPE protein affects the reaction [Bucladesine results in increased expression of STAR mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide affects the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of LIPE protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of LIPE mRNA]; NR1H2 protein affects the reaction [Bucladesine results in increased phosphorylation of LIPE protein]; NR1H2 protein affects the reaction [CAY 10499 inhibits the reaction [Bucladesine results in increased phosphorylation of LIPE protein]]; NR1H3 protein affects the reaction [Bucladesine results in increased phosphorylation of LIPE protein]; NR1H3 protein affects the reaction [CAY 10499 inhibits the reaction [Bucladesine results in increased phosphorylation of LIPE protein]]		 CTD PMID:11160373 PMID:23362264 NCBI chr19:42,401,514...42,427,388
Ensembl chr19:42,401,514...42,427,388 		JBrowse link
G LPAR3 lysophosphatidic acid receptor 3 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of LPAR3 mRNA CTD PMID:20823114 NCBI chr 1:84,811,602...84,893,206
Ensembl chr 1:84,811,602...84,893,206 		JBrowse link
G LTBP1 latent transforming growth factor beta binding protein 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of LTBP1 mRNA CTD PMID:20823114 NCBI chr 2:32,946,953...33,399,509
Ensembl chr 2:32,946,953...33,399,509 		JBrowse link
G LTC4S leukotriene C4 synthase decreases secretion EXP Bucladesine results in decreased secretion of LTC4S protein CTD PMID:16083514 NCBI chr 5:179,793,986...179,796,647
Ensembl chr 5:179,793,980...179,796,647 		JBrowse link
G MAP1A microtubule associated protein 1A multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MAP1A mRNA CTD PMID:20823114 NCBI chr15:43,510,954...43,531,611
Ensembl chr15:43,510,958...43,531,620 		JBrowse link
G MAP2 microtubule associated protein 2 multiple interactions EXP [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of MAP2 mRNA CTD PMID:29698629 NCBI chr 2:209,424,047...209,734,112
Ensembl chr 2:209,424,047...209,734,147 		JBrowse link
G MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of MAP4K4 mRNA CTD PMID:20823114 NCBI chr 2:101,697,707...101,894,690
Ensembl chr 2:101,696,850...101,894,690 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation		 EXP
ISO		 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with Bucladesine] results in increased activity of MAPK1 protein]; [1-Methyl-3-isobutylxanthine co-treated with Bucladesine] results in increased activity of MAPK1 protein
Bucladesine results in increased phosphorylation of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Bucladesine results in increased phosphorylation of MAPK1 protein]; Bucladesine results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of and results in increased activity of MAPK1 protein]]		 CTD PMID:8526880 PMID:19282384 PMID:22875961 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation		 EXP
ISO		 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with Bucladesine] results in increased activity of MAPK3 protein]; [1-Methyl-3-isobutylxanthine co-treated with Bucladesine] results in increased activity of MAPK3 protein
Bucladesine results in increased phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Bucladesine results in increased phosphorylation of MAPK3 protein]; Bucladesine results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of and results in increased activity of MAPK3 protein]]		 CTD PMID:8526880 PMID:19282384 PMID:22875961 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MGAT4B alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of MGAT4B mRNA CTD PMID:20823114 NCBI chr 5:179,797,597...179,806,866
Ensembl chr 5:179,797,597...179,806,952 		JBrowse link
G MIR125A microRNA 125a decreases expression ISO Bucladesine results in decreased expression of MIR125A mRNA CTD PMID:23045399 NCBI chr19:51,693,254...51,693,339
Ensembl chr19:51,693,254...51,693,339 		JBrowse link
G MIR145 microRNA 145 decreases expression ISO Bucladesine results in decreased expression of MIR145 mRNA CTD PMID:23045399 NCBI chr 5:149,430,646...149,430,733
Ensembl chr 5:149,430,646...149,430,733 		JBrowse link
G MIR27B microRNA 27b multiple interactions EXP [Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MIR27B mRNA CTD PMID:30328349 NCBI chr 9:95,085,445...95,085,541
Ensembl chr 9:95,085,445...95,085,541 		JBrowse link
G MIR455 microRNA 455 decreases expression ISO Bucladesine results in decreased expression of MIR455 mRNA CTD PMID:23045399 NCBI chr 9:114,209,434...114,209,529
Ensembl chr 9:114,209,434...114,209,529 		JBrowse link
G MKI67 marker of proliferation Ki-67 decreases expression ISO Bucladesine results in decreased expression of MKI67 protein CTD PMID:16718685 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423 		JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of MMP2 mRNA CTD PMID:20823114 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MTHFD2 mRNA CTD PMID:20823114 NCBI chr 2:74,198,615...74,217,565
Ensembl chr 2:74,186,172...74,217,565 		JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MTR mRNA CTD PMID:20823114 NCBI chr 1:236,795,281...236,903,981
Ensembl chr 1:236,795,260...236,921,278 		JBrowse link
G MUC12 mucin 12, cell surface associated multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MUC12 mRNA CTD PMID:20823114 NCBI chr 7:100,969,565...101,018,936
Ensembl chr 7:100,969,565...101,018,939 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor decreases expression EXP Bucladesine results in decreased expression of MYC mRNA; Bucladesine results in decreased expression of MYC protein CTD PMID:7798212 PMID:9187264 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G MYH9 myosin heavy chain 9 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MYH9 mRNA CTD PMID:20823114 NCBI chr22:36,281,280...36,387,967
Ensembl chr22:36,281,280...36,388,010 		JBrowse link
G MYL12A myosin light chain 12A multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MYL12A mRNA CTD PMID:20823114 NCBI chr18:3,247,482...3,256,237
Ensembl chr18:3,247,481...3,256,236 		JBrowse link
G MYL12B myosin light chain 12B multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MYL12B mRNA CTD PMID:20823114 NCBI chr18:3,262,133...3,278,461
Ensembl chr18:3,261,479...3,278,461 		JBrowse link
G MYLK myosin light chain kinase multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MYLK mRNA CTD PMID:20823114 NCBI chr 3:123,610,049...123,884,332
Ensembl chr 3:123,610,049...123,884,332 		JBrowse link
G MYOF myoferlin multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MYOF mRNA CTD PMID:20823114 NCBI chr10:93,306,429...93,482,334
Ensembl chr10:93,306,429...93,482,334 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NCF1 mRNA CTD PMID:20823114 NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315 		JBrowse link
G NDST1 N-deacetylase and N-sulfotransferase 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of NDST1 mRNA CTD PMID:20823114 NCBI chr 5:150,497,779...150,558,211
Ensembl chr 5:150,485,818...150,558,211 		JBrowse link
G NEFL neurofilament light chain multiple interactions EXP [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of NEFL mRNA CTD PMID:29698629 NCBI chr 8:24,950,955...24,956,612
Ensembl chr 8:24,950,955...24,956,721 		JBrowse link
G NEFM neurofilament medium chain multiple interactions EXP [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of NEFM mRNA CTD PMID:29698629 NCBI chr 8:24,913,761...24,919,093
Ensembl chr 8:24,913,758...24,919,098 		JBrowse link
G NEUROG1 neurogenin 1 multiple interactions
affects expression		 EXP bisphenol A affects the reaction [Bucladesine affects the expression of NEUROG1 mRNA]; bisphenol A affects the reaction [Bucladesine affects the expression of NEUROG1 protein]; Methylmercury Compounds affects the reaction [Bucladesine affects the expression of NEUROG1 mRNA]; Methylmercury Compounds affects the reaction [Bucladesine affects the expression of NEUROG1 protein]; Paraquat affects the reaction [Bucladesine affects the expression of NEUROG1 mRNA]; Paraquat affects the reaction [Bucladesine affects the expression of NEUROG1 protein]
Bucladesine affects the expression of NEUROG1 mRNA; Bucladesine affects the expression of NEUROG1 protein		 CTD PMID:31400064 NCBI chr 5:135,534,282...135,535,964
Ensembl chr 5:135,534,282...135,535,964 		JBrowse link
G NEXN nexilin F-actin binding protein multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NEXN mRNA CTD PMID:20823114 NCBI chr 1:77,888,624...77,943,895
Ensembl chr 1:77,888,513...77,943,895 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions
increases response to substance		 ISO [NFE2L2 gene mutant form results in increased susceptibility to Bucladesine] which results in increased expression of ALAS1 mRNA; NFE2L2 gene mutant form promotes the reaction [Bucladesine results in increased expression of CYP2A5 mRNA]; NFE2L2 gene mutant form promotes the reaction [Bucladesine results in increased expression of G6PC1 mRNA] CTD PMID:22859313 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NGF nerve growth factor multiple interactions EXP [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of ENO2 mRNA; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of MAP2 mRNA; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of NEFL mRNA; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of NEFM mRNA CTD PMID:29698629 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770 		JBrowse link
G NOM1 nucleolar protein with MIF4G domain 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NOM1 mRNA CTD PMID:20823114 NCBI chr 7:156,949,712...156,973,176
Ensembl chr 7:156,949,712...156,973,176 		JBrowse link
G NPHP1 nephrocystin 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of NPHP1 mRNA CTD PMID:20823114 NCBI chr 2:110,123,348...110,205,013
Ensembl chr 2:110,122,311...110,205,066 		JBrowse link
G NPTXR neuronal pentraxin receptor multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NPTXR mRNA CTD PMID:20823114 NCBI chr22:38,818,452...38,844,028
Ensembl chr22:38,818,452...38,844,028 		JBrowse link
G NPY neuropeptide Y increases expression ISO Bucladesine results in increased expression of NPY mRNA CTD PMID:19912776 NCBI chr 7:24,284,190...24,291,862
Ensembl chr 7:24,284,188...24,291,862 		JBrowse link
G NR0B1 nuclear receptor subfamily 0 group B member 1 decreases expression
multiple interactions		 ISO Bucladesine results in decreased expression of NR0B1 mRNA; Bucladesine results in decreased expression of NR0B1 protein
Cycloheximide inhibits the reaction [Bucladesine results in decreased expression of NR0B1 mRNA]; Dactinomycin inhibits the reaction [Bucladesine results in decreased expression of NR0B1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in decreased expression of NR0B1 protein]; NR0B1 protein inhibits the reaction [[Bucladesine results in increased expression of STAR protein] which results in increased abundance of Progesterone]; NR0B1 protein inhibits the reaction [Bucladesine results in increased expression of NR4A1 protein]; NR0B1 protein inhibits the reaction [NR4A1 protein promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; NR0B1 protein inhibits the reaction [NR5A1 protein promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]		 CTD PMID:18787026 PMID:19282384 NCBI chr  X:30,304,206...30,309,390
Ensembl chr  X:30,304,206...30,309,390 		JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 multiple interactions ISO NR1H2 protein affects the reaction [Bucladesine results in increased phosphorylation of LIPE protein]; NR1H2 protein affects the reaction [CAY 10499 inhibits the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]]; NR1H2 protein affects the reaction [CAY 10499 inhibits the reaction [Bucladesine results in increased phosphorylation of LIPE protein]] CTD PMID:23362264 NCBI chr19:50,376,457...50,383,388
Ensembl chr19:50,329,653...50,383,388 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 multiple interactions ISO NR1H3 protein affects the reaction [Bucladesine results in increased phosphorylation of LIPE protein]; NR1H3 protein affects the reaction [CAY 10499 inhibits the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]]; NR1H3 protein affects the reaction [CAY 10499 inhibits the reaction [Bucladesine results in increased phosphorylation of LIPE protein]] CTD PMID:23362264 NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033 		JBrowse link
G NR2F1 nuclear receptor subfamily 2 group F member 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NR2F1 mRNA CTD PMID:20823114 NCBI chr 5:93,583,222...93,594,611
Ensembl chr 5:93,583,222...93,594,611 		JBrowse link
G NR4A1 nuclear receptor subfamily 4 group A member 1 multiple interactions
increases expression		 ISO
EXP		 NR0B1 protein inhibits the reaction [Bucladesine results in increased expression of NR4A1 protein]; NR0B1 protein inhibits the reaction [NR4A1 protein promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; NR4A1 protein promotes the reaction [Bucladesine results in increased expression of STAR mRNA]; NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of NR4A1 protein]
[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the expression of NR4A1 mRNA; [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the expression of NR4A1 protein; [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the methylation of NR4A1 promoter; [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREB1 protein binds to NR4A1 promoter]; [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREBBP protein binds to NR4A1 promoter]; [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [EZH2 protein binds to NR4A1 promoter]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the expression of NR4A1 mRNA]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the expression of NR4A1 protein]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the methylation of NR4A1 promoter]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREB1 protein binds to NR4A1 promoter]]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREBBP protein binds to NR4A1 promoter]]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [EZH2 protein binds to NR4A1 promoter]]		 CTD PMID:18787026 PMID:19282384 PMID:36565944 NCBI chr12:52,022,832...52,059,503
Ensembl chr12:52,022,832...52,059,507 		JBrowse link
G NR5A1 nuclear receptor subfamily 5 group A member 1 multiple interactions
increases expression		 EXP
ISO		 Bucladesine inhibits the reaction [CTBP1 protein binds to NR5A1 protein]; fluorene-9-bisphenol inhibits the reaction [Bucladesine results in increased expression of NR5A1 mRNA]; fluorene-9-bisphenol inhibits the reaction [Bucladesine results in increased expression of NR5A1 protein]
Bucladesine results in increased expression of NR5A1 mRNA; Bucladesine results in increased expression of NR5A1 protein
NR0B1 protein inhibits the reaction [NR5A1 protein promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; NR5A1 protein promotes the reaction [Bucladesine results in increased expression of STAR mRNA]		 CTD PMID:18184656 PMID:18787026 PMID:35987080 NCBI chr 9:124,481,236...124,507,399
Ensembl chr 9:124,481,236...124,507,420 		JBrowse link
G NRIP1 nuclear receptor interacting protein 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NRIP1 mRNA CTD PMID:20823114 NCBI chr21:14,961,235...15,065,936
Ensembl chr21:14,961,235...15,065,936 		JBrowse link
G NT5E 5'-nucleotidase ecto multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of NT5E mRNA CTD PMID:20823114 NCBI chr 6:85,450,083...85,495,784
Ensembl chr 6:85,449,584...85,495,791 		JBrowse link
G NTF3 neurotrophin 3 increases expression ISO Bucladesine results in increased expression of NTF3 protein CTD PMID:19854260 NCBI chr12:5,430,332...5,495,299
Ensembl chr12:5,432,108...5,521,536 		JBrowse link
G NTS neurotensin multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NTS mRNA CTD PMID:20823114 NCBI chr12:85,874,295...85,882,992
Ensembl chr12:85,874,295...85,882,992 		JBrowse link
G NUP155 nucleoporin 155 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NUP155 mRNA CTD PMID:20823114 NCBI chr 5:37,288,137...37,371,106
Ensembl chr 5:37,288,137...37,371,106 		JBrowse link
G ODC1 ornithine decarboxylase 1 multiple interactions
decreases activity		 ISO 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone promotes the reaction [Bucladesine results in decreased activity of ODC1 protein] CTD PMID:6284819 NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327 		JBrowse link
G OGFRL1 opioid growth factor receptor like 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of OGFRL1 mRNA CTD PMID:20823114 NCBI chr 6:71,288,811...71,309,059
Ensembl chr 6:71,288,811...71,309,059 		JBrowse link
G OR8B8 olfactory receptor family 8 subfamily B member 8 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of OR8B8 mRNA CTD PMID:20823114 NCBI chr11:124,437,445...124,445,696
Ensembl chr11:124,437,445...124,445,696 		JBrowse link
G P4HB prolyl 4-hydroxylase subunit beta multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of P4HB mRNA CTD PMID:20823114 NCBI chr17:81,843,166...81,860,535
Ensembl chr17:81,843,159...81,860,856 		JBrowse link
G PAEP progestagen associated endometrial protein multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of PAEP mRNA CTD PMID:20823114 NCBI chr 9:135,561,756...135,566,955
Ensembl chr 9:135,561,756...135,566,955 		JBrowse link
G PALM2AKAP2 PALM2 and AKAP2 fusion multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PALM2AKAP2 mRNA CTD PMID:20823114 NCBI chr 9:109,640,787...110,172,512
Ensembl chr 9:109,498,325...110,172,512 		JBrowse link
G PAX6 paired box 6 multiple interactions
affects expression		 EXP bisphenol A affects the reaction [Bucladesine affects the expression of PAX6 mRNA]; bisphenol A affects the reaction [Bucladesine affects the expression of PAX6 protein]; Methylmercury Compounds affects the reaction [Bucladesine affects the expression of PAX6 mRNA]; Methylmercury Compounds affects the reaction [Bucladesine affects the expression of PAX6 protein]; Paraquat affects the reaction [Bucladesine affects the expression of PAX6 mRNA]; Paraquat affects the reaction [Bucladesine affects the expression of PAX6 protein]
Bucladesine affects the expression of PAX6 mRNA; Bucladesine affects the expression of PAX6 protein		 CTD PMID:31400064 NCBI chr11:31,789,026...31,817,961
Ensembl chr11:31,784,779...31,817,961 		JBrowse link
G PCDH18 protocadherin 18 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of PCDH18 mRNA CTD PMID:20823114 NCBI chr 4:137,518,918...137,532,494
Ensembl chr 4:137,518,918...137,532,494 		JBrowse link
G PCDHB4 protocadherin beta 4 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of PCDHB4 mRNA CTD PMID:20823114 NCBI chr 5:141,121,818...141,125,623
Ensembl chr 5:141,121,818...141,125,623 		JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 multiple interactions
increases expression		 ISO Metformin inhibits the reaction [Bucladesine results in increased expression of PCK1 mRNA]
Lithium Chloride inhibits the reaction [Bucladesine results in increased expression of PCK1 mRNA]		 CTD PMID:1371108 PMID:24428821 NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121 		JBrowse link
G PDGFA platelet derived growth factor subunit A decreases expression EXP Bucladesine results in decreased expression of PDGFA mRNA CTD PMID:1650039 NCBI chr 7:497,258...520,700
Ensembl chr 7:497,258...520,296 		JBrowse link
G PDK1 pyruvate dehydrogenase kinase 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PDK1 mRNA CTD PMID:20823114 NCBI chr 2:172,555,373...172,724,312
Ensembl chr 2:172,555,373...172,608,669 		JBrowse link
G PF4 platelet factor 4 increases expression
multiple interactions		 ISO Bucladesine results in increased expression of PF4 mRNA
[Bucladesine co-treated with Tetrachlorodibenzodioxin] results in increased expression of PF4 mRNA		 CTD PMID:21979172 NCBI chr 4:73,980,811...73,982,124
Ensembl chr 4:73,980,811...73,982,027 		JBrowse link
G PGRMC2 progesterone receptor membrane component 2 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PGRMC2 mRNA CTD PMID:20823114 NCBI chr 4:128,269,242...128,287,813
Ensembl chr 4:128,269,237...128,288,829 		JBrowse link
G PITPNC1 phosphatidylinositol transfer protein cytoplasmic 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of PITPNC1 mRNA CTD PMID:20823114 NCBI chr17:67,377,281...67,697,256
Ensembl chr17:67,377,281...67,697,256 		JBrowse link
G PKD2L1 polycystin 2 like 1, transient receptor potential cation channel multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PKD2L1 mRNA CTD PMID:20823114 NCBI chr10:100,288,149...100,330,228
Ensembl chr10:100,288,149...100,330,264 		JBrowse link
G PLAT plasminogen activator, tissue type multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PLAT mRNA CTD PMID:20823114 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709 		JBrowse link
G PLEKHG3 pleckstrin homology and RhoGEF domain containing G3 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PLEKHG3 mRNA CTD PMID:20823114 NCBI chr14:64,704,424...64,750,249
Ensembl chr14:64,704,102...64,750,249 		JBrowse link
G PLIN1 perilipin 1 increases expression
multiple interactions		 ISO Bucladesine results in increased expression of PLIN1 mRNA
LIPE protein affects the reaction [Bucladesine results in increased expression of PLIN1 mRNA]		 CTD PMID:23362264 NCBI chr15:89,664,367...89,679,367
Ensembl chr15:89,664,367...89,679,427 		JBrowse link
G PLS3 plastin 3 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of PLS3 mRNA CTD PMID:20823114 NCBI chr  X:115,561,174...115,650,861
Ensembl chr  X:115,561,174...115,650,861 		JBrowse link
G PMP22 peripheral myelin protein 22 multiple interactions
increases activity		 ISO Ascorbic Acid inhibits the reaction [Bucladesine results in increased activity of PMP22 promoter] CTD PMID:15034573 NCBI chr17:15,229,779...15,265,326
Ensembl chr17:15,229,773...15,272,292 		JBrowse link
G PNPLA6 patatin like phospholipase domain containing 6 increases expression
multiple interactions		 EXP Bucladesine results in increased expression of PNPLA6 mRNA
Bucladesine results in increased expression of and results in increased activity of PNPLA6 protein; Cycloheximide inhibits the reaction [Bucladesine results in increased activity of PNPLA6 protein]		 CTD PMID:20380879 NCBI chr19:7,534,164...7,561,767
Ensembl chr19:7,534,004...7,561,764 		JBrowse link
G POMC proopiomelanocortin increases expression EXP Bucladesine results in increased expression of POMC mRNA; Bucladesine results in increased expression of POMC protein modified form CTD PMID:1325994 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903 		JBrowse link
G POU5F1 POU class 5 homeobox 1 multiple interactions
affects expression		 EXP bisphenol A affects the reaction [Bucladesine affects the expression of POU5F1 mRNA]; bisphenol A affects the reaction [Bucladesine affects the expression of POU5F1 protein]; Methylmercury Compounds affects the reaction [Bucladesine affects the expression of POU5F1 mRNA]; Methylmercury Compounds affects the reaction [Bucladesine affects the expression of POU5F1 protein]; Paraquat affects the reaction [Bucladesine affects the expression of POU5F1 mRNA]; Paraquat affects the reaction [Bucladesine affects the expression of POU5F1 protein]
Bucladesine affects the expression of POU5F1 mRNA; Bucladesine affects the expression of POU5F1 protein		 CTD PMID:31400064 NCBI chr 6:31,164,337...31,170,682
Ensembl chr 6:31,164,337...31,180,731 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma increases expression
multiple interactions		 ISO Bucladesine results in increased expression of PPARG protein
[ciglitazone co-treated with Bucladesine] affects the expression of PPARG mRNA; [ciglitazone co-treated with Bucladesine] results in increased expression of PPARG protein		 CTD PMID:19698295 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha increases expression
multiple interactions		 ISO Bucladesine results in increased expression of PPARGC1A mRNA; Bucladesine results in increased expression of PPARGC1A protein
IL22 protein inhibits the reaction [Bucladesine results in increased expression of PPARGC1A protein]; Metformin inhibits the reaction [Bucladesine results in increased expression of PPARGC1A mRNA]		 CTD PMID:24428821 PMID:26064446 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G PPIA peptidylprolyl isomerase A multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of PPIA mRNA CTD PMID:20823114 NCBI chr 7:44,796,681...44,803,117
Ensembl chr 7:44,796,680...44,824,564 		JBrowse link
G PPIAL4A peptidylprolyl isomerase A like 4A multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of PPIAL4A mRNA CTD PMID:20823114 NCBI chr 1:120,889,771...120,890,530
Ensembl chr 1:120,889,771...120,890,530 		JBrowse link
G PRIMA1 proline rich membrane anchor 1 increases expression ISO Bucladesine results in increased expression of PRIMA1 mRNA CTD PMID:18514641 NCBI chr14:93,718,298...93,788,994
Ensembl chr14:93,718,298...93,788,485 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha increases activity
multiple interactions		 ISO Bucladesine results in increased activity of PRKACA protein
KT 5720 inhibits the reaction [Bucladesine results in increased activity of PRKACA protein]		 CTD PMID:31300867 NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084 		JBrowse link
G PRL prolactin multiple interactions EXP [Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PRL mRNA; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of PRL mRNA; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of PRL protein; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PRL mRNA; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PRL protein; [Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased secretion of PRL protein; AGT protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased secretion of PRL protein]; Losartan inhibits the reaction [AGT protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased secretion of PRL protein]] CTD PMID:20823114 PMID:30328349 PMID:36682589 NCBI chr 6:22,287,246...22,302,835
Ensembl chr 6:22,287,244...22,302,826 		JBrowse link
G PRSS12 serine protease 12 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of PRSS12 mRNA CTD PMID:20823114 NCBI chr 4:118,280,038...118,353,003
Ensembl chr 4:118,280,038...118,353,003 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP
ISO		 Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [Dinoprostone results in increased expression of PTGS2 mRNA]]; Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [Dinoprostone results in increased expression of PTGS2 protein]]; Bucladesine promotes the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]
Bucladesine promotes the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]		 CTD PMID:11095985 PMID:12164941 PMID:24003391 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTK7 protein tyrosine kinase 7 (inactive) multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PTK7 mRNA CTD PMID:20823114 NCBI chr 6:43,076,314...43,161,715
Ensembl chr 6:43,076,307...43,161,719 		JBrowse link
G PTPA protein phosphatase 2 phosphatase activator multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PTPA mRNA CTD PMID:20823114 NCBI chr 9:129,110,950...129,148,946
Ensembl chr 9:129,110,950...129,148,946 		JBrowse link
G RAB1B RAB1B, member RAS oncogene family multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of RAB1B mRNA CTD PMID:20823114 NCBI chr11:66,268,639...66,277,492
Ensembl chr11:66,268,590...66,277,492 		JBrowse link
G RAB31 RAB31, member RAS oncogene family multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of RAB31 mRNA CTD PMID:20823114 NCBI chr18:9,708,301...9,862,551
Ensembl chr18:9,708,275...9,862,551 		JBrowse link
G RAN RAN, member RAS oncogene family multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RAN mRNA CTD PMID:20823114 NCBI chr12:130,872,066...130,877,678
Ensembl chr12:130,872,037...130,877,678 		JBrowse link
G RB1 RB transcriptional corepressor 1 decreases activity
decreases phosphorylation
multiple interactions		 EXP
ISO		 Bucladesine results in decreased activity of RB1 protein
Bucladesine results in decreased phosphorylation of RB1 protein
Bucladesine inhibits the reaction [CASP3 protein results in increased cleavage of RB1 protein]		 CTD PMID:10697531 PMID:16718685 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436 		JBrowse link
G REN renin increases secretion
increases expression		 EXP Bucladesine results in increased secretion of REN protein
Bucladesine results in increased expression of REN mRNA		 CTD PMID:9256163 NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324 		JBrowse link
G RET ret proto-oncogene multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RET mRNA CTD PMID:20823114 NCBI chr10:43,077,069...43,130,351
Ensembl chr10:43,077,064...43,130,351 		JBrowse link
G RGS10 regulator of G protein signaling 10 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RGS10 mRNA CTD PMID:20823114 NCBI chr10:119,499,817...119,542,719
Ensembl chr10:119,499,817...119,542,719 		JBrowse link
G RHOBTB3 Rho related BTB domain containing 3 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RHOBTB3 mRNA CTD PMID:20823114 NCBI chr 5:95,717,624...95,796,361
Ensembl chr 5:95,713,522...95,824,383 		JBrowse link
G RIN1 Ras and Rab interactor 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of RIN1 mRNA CTD PMID:20823114 NCBI chr11:66,330,241...66,336,774
Ensembl chr11:66,330,241...66,336,840 		JBrowse link
G RPL5P29 ribosomal protein L5 pseudogene 29 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RPL5P29 mRNA CTD PMID:20823114 NCBI chr11:56,357,273...56,358,282
Ensembl chr11:56,357,328...56,358,221 		JBrowse link
G RPN1 ribophorin I multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of RPN1 mRNA CTD PMID:20823114 NCBI chr 3:128,619,969...128,650,818
Ensembl chr 3:128,619,969...128,681,075 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of RPS6KB1 mRNA CTD PMID:20823114 NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574 		JBrowse link
G RPSA ribosomal protein SA multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RPSA mRNA CTD PMID:20823114 NCBI chr 3:39,406,720...39,412,542
Ensembl chr 3:39,406,716...39,426,255 		JBrowse link
G RPSAP12 ribosomal protein SA pseudogene 12 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RPSAP12 mRNA CTD PMID:20823114 NCBI chr12:68,552,925...68,553,958
Ensembl chr12:68,552,995...68,553,882 		JBrowse link
G RPSAP28 ribosomal protein SA pseudogene 28 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RPSAP28 mRNA CTD PMID:20823114 NCBI chr 2:73,369,951...73,370,963
Ensembl chr 2:73,370,019...73,370,892 		JBrowse link
G RPSAP3 ribosomal protein SA pseudogene 3 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RPSAP3 mRNA CTD PMID:20823114 NCBI chr14:76,634,705...76,635,737
Ensembl chr14:76,634,775...76,635,661 		JBrowse link
G RPSAP31 ribosomal protein SA pseudogene 31 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RPSAP31 mRNA CTD PMID:20823114 NCBI chr 3:183,887,522...183,888,537
Ensembl chr 3:183,887,555...183,888,449 		JBrowse link
G S100A14 S100 calcium binding protein A14 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of S100A14 mRNA CTD PMID:20823114 NCBI chr 1:153,614,255...153,616,325
Ensembl chr 1:153,614,255...153,616,986 		JBrowse link
G SARAF store-operated calcium entry associated regulatory factor multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of SARAF mRNA CTD PMID:20823114 NCBI chr 8:30,063,003...30,083,208
Ensembl chr 8:30,063,003...30,083,208 		JBrowse link
G SCAMP4 secretory carrier membrane protein 4 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of SCAMP4 mRNA CTD PMID:20823114 NCBI chr19:1,905,399...1,926,013
Ensembl chr19:1,905,214...1,926,013 		JBrowse link
G SCARB1 scavenger receptor class B member 1 multiple interactions
increases expression		 ISO LIPE protein affects the reaction [Bucladesine results in increased expression of SCARB1 mRNA] CTD PMID:23045399 PMID:23362264 NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668 		JBrowse link
G SDCBP syndecan binding protein multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of SDCBP mRNA CTD PMID:20823114 NCBI chr 8:58,553,261...58,582,858
Ensembl chr 8:58,552,924...58,582,859 		JBrowse link
G SELENOT selenoprotein T multiple interactions
increases expression		 ISO 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Bucladesine results in increased expression of SELENOT mRNA]; nickel chloride inhibits the reaction [Bucladesine results in increased expression of SELENOT mRNA] CTD PMID:18198219 NCBI chr 3:150,603,321...150,630,436
Ensembl chr 3:150,602,875...150,630,436 		JBrowse link
G SEMA3A semaphorin 3A multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of SEMA3A mRNA CTD PMID:20823114 NCBI chr 7:83,955,777...84,492,725
Ensembl chr 7:83,955,777...84,492,724 		JBrowse link
G SEPTIN11 septin 11 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of SEPTIN11 mRNA CTD PMID:20823114 NCBI chr 4:76,949,752...77,040,154
Ensembl chr 4:76,949,751...77,040,384 		JBrowse link
G SFN stratifin multiple interactions EXP [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression of SFN mRNA; [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of SFN protein CTD PMID:22534328 NCBI chr 1:26,863,149...26,864,456
Ensembl chr 1:26,863,149...26,864,456 		JBrowse link
G SIRPB1 signal regulatory protein beta 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of SIRPB1 mRNA CTD PMID:20823114 NCBI chr20:1,561,385...1,620,009
Ensembl chr20:1,561,385...1,620,061 		JBrowse link
G SLC18A3 solute carrier family 18 member A3 increases expression
multiple interactions		 ISO Bucladesine results in increased expression of SLC18A3 protein
Nicotine promotes the reaction [Bucladesine results in increased expression of SLC18A3 protein]		 CTD PMID:20361958 NCBI chr10:49,610,310...49,612,720
Ensembl chr10:49,610,310...49,612,720 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 multiple interactions EXP [Progesterone co-treated with Bucladesine] results in increased expression of SLC2A1 protein CTD PMID:18948400 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893 		JBrowse link
G SLC2A5 solute carrier family 2 member 5 multiple interactions EXP Bucladesine results in increased expression of and results in increased stability of SLC2A5 mRNA; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of and results in increased stability of SLC2A5 mRNA] CTD PMID:12820898 NCBI chr 1:9,035,106...9,094,195
Ensembl chr 1:9,035,106...9,088,478 		JBrowse link
G SMAD6 SMAD family member 6 multiple interactions EXP Bucladesine inhibits the reaction [BMP4 protein results in increased expression of SMAD6 mRNA] CTD PMID:20522807 NCBI chr15:66,702,236...66,782,849
Ensembl chr15:66,702,236...66,782,849 		JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions
increases expression
increases activity		 EXP Bucladesine promotes the reaction [CREBBP protein binds to SOD2 promoter]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of SOD2 mRNA]; protein kinase inhibitor peptide inhibits the reaction [Bucladesine results in increased activity of SOD2 protein] CTD PMID:12093828 PMID:20685861 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SOX1 SRY-box transcription factor 1 multiple interactions
affects expression		 EXP bisphenol A affects the reaction [Bucladesine affects the expression of SOX1 mRNA]; bisphenol A affects the reaction [Bucladesine affects the expression of SOX1 protein]; Methylmercury Compounds affects the reaction [Bucladesine affects the expression of SOX1 mRNA]; Methylmercury Compounds affects the reaction [Bucladesine affects the expression of SOX1 protein]; Paraquat affects the reaction [Bucladesine affects the expression of SOX1 mRNA]; Paraquat affects the reaction [Bucladesine affects the expression of SOX1 protein]
Bucladesine affects the expression of SOX1 mRNA; Bucladesine affects the expression of SOX1 protein		 CTD PMID:31400064 NCBI chr13:112,067,149...112,071,706
Ensembl chr13:112,067,149...112,071,706 		JBrowse link
G SRSF7 serine and arginine rich splicing factor 7 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of SRSF7 mRNA CTD PMID:20823114 NCBI chr 2:38,743,599...38,751,494
Ensembl chr 2:38,743,599...38,751,494 		JBrowse link
G STAR steroidogenic acute regulatory protein multiple interactions
increases expression
decreases expression		 ISO
EXP		 27-hydroxycholesterol promotes the reaction [STAR protein promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol]]; [[T0901317 co-treated with LG 100268] promotes the reaction [Bucladesine results in increased phosphorylation of STAR protein]] which results in increased abundance of Progesterone; [Bucladesine co-treated with ciglitazone] results in increased expression of STAR mRNA; [Bucladesine co-treated with ciglitazone] results in increased phosphorylation of STAR protein; [Bucladesine co-treated with LIPE protein] results in increased expression of and results in increased phosphorylation of STAR protein; [Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]] promotes the reaction [CREBBP protein binds to STAR promoter]; [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone; [Bucladesine results in increased expression of STAR protein] which results in increased abundance of Progesterone; [ciglitazone co-treated with Bucladesine] promotes the reaction [JUN protein results in increased expression of STAR mRNA]; [T0901317 co-treated with LG 100268] promotes the reaction [Bucladesine results in increased phosphorylation of STAR protein]; alpha-hexachlorocyclohexane inhibits the reaction [Bucladesine results in increased expression of STAR mRNA]; alpha-hexachlorocyclohexane inhibits the reaction [Bucladesine results in increased expression of STAR protein]; bisindolylmaleimide I inhibits the reaction [Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR protein]]; Bucladesine promotes the reaction [ciglitazone results in increased expression of STAR mRNA]; Bucladesine promotes the reaction [ciglitazone results in increased expression of STAR protein]; Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]; Bucladesine promotes the reaction [LG 100268 promotes the reaction [[T0901317 results in increased expression of STAR mRNA] which results in increased abundance of Progesterone]]; Bucladesine promotes the reaction [LG 100268 promotes the reaction [[T0901317 results in increased expression of STAR protein] which results in increased abundance of Progesterone]]; Bucladesine promotes the reaction [LG 100268 promotes the reaction [T0901317 results in increased expression of STAR mRNA]]; Bucladesine promotes the reaction [T0901317 promotes the reaction [[LG 100268 results in increased expression of STAR mRNA] which results in increased abundance of Progesterone]]; Bucladesine promotes the reaction [T0901317 promotes the reaction [[LG 100268 results in increased expression of STAR protein] which results in increased abundance of Progesterone]]; Bucladesine promotes the reaction [T0901317 promotes the reaction [LG 100268 results in increased expression of STAR mRNA]]; Bucladesine results in increased expression of and results in increased phosphorylation of STAR mRNA; Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein; CAY 10499 inhibits the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]; ciglitazone promotes the reaction [Bucladesine results in increased expression of STAR mRNA]; ciglitazone promotes the reaction [Bucladesine results in increased expression of STAR protein]; CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; CREBBP protein promotes the reaction [CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]]; delta-hexachlorocyclohexane inhibits the reaction [Bucladesine results in increased expression of STAR mRNA]; delta-hexachlorocyclohexane inhibits the reaction [Bucladesine results in increased expression of STAR protein]; GFX 109203x inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]]; Hexachlorocyclohexane inhibits the reaction [Bucladesine results in increased expression of STAR mRNA]; Hexachlorocyclohexane inhibits the reaction [Bucladesine results in increased expression of STAR protein]; lead acetate inhibits the reaction [Bucladesine results in increased expression of STAR protein]; LIPE protein affects the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]; LIPE protein affects the reaction [Bucladesine results in increased expression of STAR mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of STAR mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]]; NR0B1 protein inhibits the reaction [[Bucladesine results in increased expression of STAR protein] which results in increased abundance of Progesterone]; NR0B1 protein inhibits the reaction [NR4A1 protein promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; NR0B1 protein inhibits the reaction [NR5A1 protein promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; NR1H2 protein affects the reaction [CAY 10499 inhibits the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]]; NR1H3 protein affects the reaction [CAY 10499 inhibits the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]]; NR4A1 protein promotes the reaction [Bucladesine results in increased expression of STAR mRNA]; NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; NR5A1 protein promotes the reaction [Bucladesine results in increased expression of STAR mRNA]; Probucol inhibits the reaction [STAR protein promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol]]; STAR protein promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased expression of ABCA1 mRNA]; STAR protein promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol]; Tetradecanoylphorbol Acetate promotes the reaction [[Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR protein]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of STAR protein]; U 0126 inhibits the reaction [Bucladesine results in increased phosphorylation of STAR protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of STAR protein]]
fluorene-9-bisphenol inhibits the reaction [Bucladesine results in increased expression of STAR mRNA]
Bucladesine results in increased expression of STAR mRNA; Bucladesine results in increased expression of STAR protein
Bucladesine results in decreased expression of STAR mRNA
[Atrazine co-treated with Bucladesine] results in increased expression of STAR mRNA; Atrazine inhibits the reaction [Bucladesine results in increased expression of STAR mRNA]; Quercetin inhibits the reaction [[Atrazine co-treated with Bucladesine] results in increased expression of STAR mRNA]		 CTD PMID:10964798 PMID:10993823 PMID:11213355 PMID:18755854 PMID:18787026 More... NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 multiple interactions ISO STAT3 gene mutant form affects the reaction [IL22 protein inhibits the reaction [Bucladesine results in increased expression of G6PC1 protein]] CTD PMID:26064446 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G STK38 serine/threonine kinase 38 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of STK38 mRNA CTD PMID:20823114 NCBI chr 6:36,493,892...36,547,479
Ensembl chr 6:36,493,892...36,547,479 		JBrowse link
G SULF1 sulfatase 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of SULF1 mRNA CTD PMID:20823114 NCBI chr 8:69,466,781...69,660,912
Ensembl chr 8:69,466,624...69,660,915 		JBrowse link
G TAGLN transgelin multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of TAGLN mRNA CTD PMID:20823114 NCBI chr11:117,199,294...117,207,465
Ensembl chr11:117,199,370...117,207,464 		JBrowse link
G TCEA1 transcription elongation factor A1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of TCEA1 mRNA CTD PMID:20823114 NCBI chr 8:53,966,556...54,022,448
Ensembl chr 8:53,966,552...54,022,448 		JBrowse link
G TERT telomerase reverse transcriptase multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of TERT mRNA CTD PMID:20823114 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068 		JBrowse link
G TFRC transferrin receptor decreases expression EXP Bucladesine results in decreased expression of TFRC protein CTD PMID:2989362 NCBI chr 3:196,049,284...196,082,090
Ensembl chr 3:196,012,511...196,082,153 		JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions EXP Bucladesine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Bucladesine inhibits the reaction [TGFB1 protein results in increased expression of COL3A1 mRNA] CTD PMID:11576339 PMID:16430859 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TGM2 transglutaminase 2 multiple interactions ISO [O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate co-treated with Bucladesine] results in increased activity of TGM2 protein; [phenylsaligenin cyclic phosphate co-treated with Bucladesine] results in increased activity of TGM2 protein CTD PMID:32749514 NCBI chr20:38,127,385...38,168,475
Ensembl chr20:38,127,385...38,166,578 		JBrowse link
G TH tyrosine hydroxylase increases expression ISO Bucladesine results in increased expression of TH mRNA CTD PMID:19912776 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815 		JBrowse link
G TJP1 tight junction protein 1 multiple interactions ISO Bucladesine inhibits the reaction [tert-Butylhydroperoxide affects the localization of TJP1 protein] CTD PMID:16716901 NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915 		JBrowse link
G TNC tenascin C multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of TNC mRNA CTD PMID:20823114 NCBI chr 9:115,019,575...115,118,157
Ensembl chr 9:115,019,575...115,118,207 		JBrowse link
G TNF tumor necrosis factor multiple interactions EXP
ISO		 Bucladesine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Bucladesine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Bucladesine inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
Bucladesine inhibits the reaction [Dopamine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of TNF protein]]; Bucladesine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF protein]
Bucladesine inhibits the reaction [Zymosan results in increased expression of TNF protein]		 CTD PMID:11301049 PMID:12509806 PMID:12538815 PMID:15081246 PMID:20388727 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TP53 tumor protein p53 multiple interactions EXP [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression of TP53 protein; [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of TP53 protein CTD PMID:22534328 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538 		JBrowse link
G TPI1 triosephosphate isomerase 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of TPI1 mRNA CTD PMID:20823114 NCBI chr12:6,867,420...6,870,948
Ensembl chr12:6,867,119...6,870,948 		JBrowse link
G TPSG1 tryptase gamma 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of TPSG1 mRNA CTD PMID:20823114 NCBI chr16:1,221,651...1,225,268
Ensembl chr16:1,221,651...1,225,793 		JBrowse link
G TXN thioredoxin multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of TXN mRNA CTD PMID:20823114 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507 		JBrowse link
G UBE2D4 ubiquitin conjugating enzyme E2 D4 (putative) multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of UBE2D4 mRNA CTD PMID:20823114 NCBI chr 7:43,926,436...43,956,136
Ensembl chr 7:43,926,436...43,956,136 		JBrowse link
G UCP1 uncoupling protein 1 increases expression
multiple interactions		 ISO Bucladesine results in increased expression of UCP1 mRNA
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of UCP1 mRNA]		 CTD PMID:12414803 NCBI chr 4:140,559,431...140,568,961
Ensembl chr 4:140,559,431...140,568,961 		JBrowse link
G UGCG UDP-glucose ceramide glucosyltransferase multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of UGCG mRNA CTD PMID:20823114 NCBI chr 9:111,896,814...111,935,369
Ensembl chr 9:111,896,814...111,935,369 		JBrowse link
G UGT2B15 UDP glucuronosyltransferase family 2 member B15 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of UGT2B15 mRNA CTD PMID:20823114 NCBI chr 4:68,646,597...68,670,652
Ensembl chr 4:68,646,597...68,670,652 		JBrowse link
G USP12 ubiquitin specific peptidase 12 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of USP12 mRNA CTD PMID:20823114 NCBI chr13:27,066,156...27,171,811
Ensembl chr13:27,066,156...27,171,811 		JBrowse link
G VEGFA vascular endothelial growth factor A increases expression EXP Bucladesine results in increased expression of VEGFA mRNA CTD PMID:18591213 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G VIM vimentin multiple interactions EXP [Azacitidine co-treated with Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of VIM protein CTD PMID:20823114 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
G VPS39 VPS39 subunit of HOPS complex multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of VPS39 mRNA CTD PMID:20823114 NCBI chr15:42,158,701...42,208,304
Ensembl chr15:42,158,701...42,208,307 		JBrowse link
G WNT5A Wnt family member 5A multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of WNT5A mRNA CTD PMID:20823114 NCBI chr 3:55,465,715...55,505,263
Ensembl chr 3:55,465,715...55,490,539 		JBrowse link
G WWTR1 WW domain containing transcription regulator 1 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of WWTR1 mRNA CTD PMID:20823114 NCBI chr 3:149,517,235...149,724,788
Ensembl chr 3:149,517,235...149,736,714 		JBrowse link
G ZBTB45 zinc finger and BTB domain containing 45 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of ZBTB45 mRNA CTD PMID:20823114 NCBI chr19:58,513,530...58,542,718
Ensembl chr19:58,513,530...58,538,911 		JBrowse link
G ZNF135 zinc finger protein 135 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of ZNF135 mRNA CTD PMID:20823114 NCBI chr19:58,059,239...58,069,755
Ensembl chr19:58,059,239...58,086,310 		JBrowse link
G ZNF530 zinc finger protein 530 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of ZNF530 mRNA CTD PMID:20823114 NCBI chr19:57,599,885...57,612,722
Ensembl chr19:57,599,885...57,612,722 		JBrowse link
G ZSCAN10 zinc finger and SCAN domain containing 10 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of ZSCAN10 mRNA CTD PMID:20823114 NCBI chr16:3,088,890...3,099,294
Ensembl chr16:3,088,890...3,099,295 		JBrowse link
G ZSCAN20 zinc finger and SCAN domain containing 20 multiple interactions EXP [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of ZSCAN20 mRNA CTD PMID:20823114 NCBI chr 1:33,472,645...33,501,643
Ensembl chr 1:33,472,645...33,501,643 		JBrowse link
butyryl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KAT2B lysine acetyltransferase 2B affects binding ISO butyryl-coenzyme A binds to KAT2B protein CTD PMID:28077572 NCBI chr 3:20,040,446...20,154,404
Ensembl chr 3:20,040,446...20,154,404 		JBrowse link
c-di-GMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TDRD7 tudor domain containing 7 increases expression ISO bis(3',5')-cyclic diguanylic acid results in increased expression of TDRD7 mRNA CTD PMID:32273341 NCBI chr 9:97,412,096...97,496,125
Ensembl chr 9:97,412,096...97,496,125 		JBrowse link
cangrelor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F3 coagulation factor III, tissue factor multiple interactions EXP cangrelor results in decreased expression of and results in decreased activity of F3 protein; Indomethacin promotes the reaction [cangrelor results in decreased expression of and results in decreased activity of F3 protein] CTD PMID:20200314 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759 		JBrowse link
G GPR17 G protein-coupled receptor 17 multiple interactions ISO cangrelor inhibits the reaction [Uridine Diphosphate results in increased activity of GPR17 protein] CTD PMID:18974869 NCBI chr 2:127,646,153...127,652,639
Ensembl chr 2:127,645,864...127,652,639 		JBrowse link
G ITGA2B integrin subunit alpha 2b multiple interactions EXP cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]] CTD PMID:18404433 NCBI chr17:44,372,181...44,389,649
Ensembl chr17:44,372,180...44,389,649 		JBrowse link
G ITGB3 integrin subunit beta 3 multiple interactions EXP cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]] CTD PMID:18404433 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,827...47,313,743 		JBrowse link
G P2RY12 purinergic receptor P2Y12 multiple interactions
decreases activity
affects response to substance		 EXP [cangrelor binds to and results in decreased activity of P2RY12 protein] which results in decreased abundance of phosphatidylinositol 3,4,5-triphosphate; [cangrelor binds to and results in decreased activity of P2RY12 protein] which results in decreased phosphorylation of SYK protein
cangrelor results in decreased activity of P2RY12 protein
P2RY12 gene polymorphism affects the susceptibility to cangrelor		 CTD PMID:12606772 PMID:20126830 PMID:22273509 NCBI chr 3:151,336,843...151,384,753
Ensembl chr 3:151,336,843...151,384,753 		JBrowse link
G PF4 platelet factor 4 multiple interactions EXP cangrelor inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY results in increased secretion of PF4 protein] CTD PMID:22273509 NCBI chr 4:73,980,811...73,982,124
Ensembl chr 4:73,980,811...73,982,027 		JBrowse link
G SELP selectin P multiple interactions EXP cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]] CTD PMID:18404433 NCBI chr 1:169,588,849...169,630,124
Ensembl chr 1:169,588,849...169,630,193 		JBrowse link
G SYK spleen associated tyrosine kinase multiple interactions EXP [cangrelor binds to and results in decreased activity of P2RY12 protein] which results in decreased phosphorylation of SYK protein CTD PMID:12606772 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549 		JBrowse link
CDP-choline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP3 caspase 3 decreases expression EXP Cytidine Diphosphate Choline results in decreased expression of CASP3 protein CTD PMID:12443983 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 decreases expression ISO Cytidine Diphosphate Choline results in decreased expression of ICAM1 mRNA CTD PMID:16193989 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G NCEH1 neutral cholesterol ester hydrolase 1 multiple interactions ISO NCEH1 protein inhibits the reaction [[Chlorpyrifos metabolite co-treated with Cytidine Diphosphate Choline] results in increased abundance of Platelet Activating Factor] CTD PMID:18164358 NCBI chr 3:172,630,249...172,711,067
Ensembl chr 3:172,630,249...172,711,218 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 decreases expression EXP Cytidine Diphosphate Choline results in decreased expression of PARP1 protein modified form CTD PMID:12443983 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G SIRT1 sirtuin 1 increases expression
multiple interactions		 ISO Cytidine Diphosphate Choline results in increased expression of SIRT1 protein
Cytidine Diphosphate Choline results in increased expression of and results in increased activity of SIRT1 protein		 CTD PMID:23600725 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
CMP-N-acetyl-beta-neuraminic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CMAS cytidine monophosphate N-acetylneuraminic acid synthetase affects abundance EXP CMAS protein affects the abundance of Cytidine Monophosphate N-Acetylneuraminic Acid CTD PMID:27380425 NCBI chr12:22,046,218...22,065,668
Ensembl chr12:22,046,218...22,065,674 		JBrowse link
coenzyme A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOT8 acyl-CoA thioesterase 8 affects hydrolysis ISO ACOT8 protein affects the hydrolysis of Coenzyme A analog CTD PMID:16141203 NCBI chr20:45,841,721...45,857,392
Ensembl chr20:45,841,721...45,857,405 		JBrowse link
G KAT2B lysine acetyltransferase 2B affects binding ISO Coenzyme A binds to KAT2B protein CTD PMID:28077572 NCBI chr 3:20,040,446...20,154,404
Ensembl chr 3:20,040,446...20,154,404 		JBrowse link
CTP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor multiple interactions ISO Cytidine Triphosphate affects the folding of [Tetrachlorodibenzodioxin binds to AHR protein] CTD PMID:1848756 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G APP amyloid beta precursor protein increases secretion EXP Cytidine Triphosphate results in increased secretion of APP protein modified form CTD PMID:22906069 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G P2RX1 purinergic receptor P2X 1 affects binding ISO CTP binds to P2rx1 protein RGD PMID:12237343 RGD:727431 NCBI chr17:3,896,592...3,916,465
Ensembl chr17:3,896,592...3,916,476 		JBrowse link
G P2RX5 purinergic receptor P2X 5 affects transport ISO CTP affects transport ion flux of P2rx5 receptor RGD PMID:12237343 RGD:727431 NCBI chr17:3,673,227...3,696,155
Ensembl chr17:3,672,199...3,696,240 		JBrowse link
cyclic ADP-beta-D-ribose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD38 CD38 molecule decreases abundance ISO CD38 gene mutant form results in decreased abundance of Cyclic ADP-Ribose CTD PMID:23343681 NCBI chr 4:15,778,328...15,853,232
Ensembl chr 4:15,778,275...15,853,232 		JBrowse link
G HOMER1 homer scaffold protein 1 multiple interactions ISO HOMER1 protein alternative form inhibits the reaction [Cyclic ADP-Ribose promotes the reaction [RYR2 protein results in increased secretion of Calcium]] CTD PMID:12887973 NCBI chr 5:79,372,636...79,514,134
Ensembl chr 5:79,372,636...79,514,134 		JBrowse link
G RYR2 ryanodine receptor 2 multiple interactions ISO HOMER1 protein alternative form inhibits the reaction [Cyclic ADP-Ribose promotes the reaction [RYR2 protein results in increased secretion of Calcium]] CTD PMID:12887973 NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988 		JBrowse link
cytidine 5'-monophosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase multiple interactions ISO [delta-hexachlorocyclohexane results in decreased activity of CDIPT protein] which results in decreased abundance of Cytidine Monophosphate; [Inositol promotes the reaction [CDIPT protein results in increased metabolism of Cytidine Diphosphate Diglycerides]] which results in increased abundance of Cytidine Monophosphate CTD PMID:2579070 NCBI chr16:29,858,357...29,863,226
Ensembl chr16:29,858,357...29,863,414 		JBrowse link
D-ribofuranose 5-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TALDO1 transaldolase 1 increases abundance ISO TALDO1 gene mutant form results in increased abundance of ribose-5-phosphate CTD PMID:19436114 NCBI chr11:747,464...765,012
Ensembl chr11:747,415...765,012 		JBrowse link
decanoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSDL2 hydroxysteroid dehydrogenase like 2 multiple interactions EXP [decanoyl-coenzyme A co-treated with NADP] binds to HSDL2 protein CTD PMID:25526675 NCBI chr 9:112,380,108...112,472,405
Ensembl chr 9:112,380,080...112,472,405 		JBrowse link
G PECR peroxisomal trans-2-enoyl-CoA reductase multiple interactions EXP [decanoyl-coenzyme A co-treated with NADP] binds to PECR protein CTD PMID:25526675 NCBI chr 2:216,029,088...216,081,809
Ensembl chr 2:215,996,329...216,082,955 		JBrowse link
FMN term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 increases abundance
multiple interactions		 ISO IDH2 protein mutant form results in increased abundance of Flavin Mononucleotide
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Flavin Mononucleotide]		 CTD PMID:27469509 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477 		JBrowse link
G RFK riboflavin kinase increases abundance EXP RFK protein results in increased abundance of Flavin Mononucleotide CTD PMID:21308351 NCBI chr 9:76,385,526...76,394,426
Ensembl chr 9:76,385,526...76,394,517 		JBrowse link
G SLC52A3 solute carrier family 52 member 3 multiple interactions ISO Flavin Mononucleotide inhibits the reaction [SLC52A3 protein results in increased transport of Riboflavin] CTD PMID:19122205 NCBI chr20:760,080...780,033
Ensembl chr20:760,080...776,015 		JBrowse link
GDP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FUT8 fucosyltransferase 8 multiple interactions
decreases activity		 EXP Guanosine Diphosphate inhibits the reaction [Mersalyl results in decreased activity of FUT8 protein]; Guanosine Diphosphate inhibits the reaction [p-Chloromercuribenzoic Acid results in decreased activity of FUT8 protein]; Guanosine Diphosphate inhibits the reaction [Phenylglyoxal results in decreased activity of FUT8 protein]
Guanosine Diphosphate results in decreased activity of FUT8 protein		 CTD PMID:12770769 NCBI chr14:65,356,842...65,744,121
Ensembl chr14:65,410,592...65,744,121 		JBrowse link
G GMDS GDP-mannose 4,6-dehydratase affects binding EXP Guanosine Diphosphate binds to GMDS protein CTD PMID:25526675 NCBI chr 6:1,623,806...2,245,605
Ensembl chr 6:1,623,806...2,245,605 		JBrowse link
G H2AX H2A.X variant histone multiple interactions EXP Guanosine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form] CTD PMID:32941855 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465 		JBrowse link
G HRAS HRas proto-oncogene, GTPase multiple interactions EXP [Enzyme Inhibitors binds to and results in decreased activity of SOS1 protein] promotes the reaction [HRAS protein binds to Guanosine Diphosphate]; Enzyme Inhibitors inhibits the reaction [SOS1 protein binds to [HRAS protein binds to Guanosine Diphosphate]] CTD PMID:25825487 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A multiple interactions ISO Guanosine Diphosphate affects the reaction [Serotonin inhibits the reaction [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to HTR1A protein]] CTD PMID:21126535 NCBI chr 5:63,957,874...63,962,445
Ensembl chr 5:63,957,874...63,962,507 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase multiple interactions
affects binding		 EXP KRAS protein mutant form inhibits the reaction [SOS1 protein inhibits the reaction [Guanosine Diphosphate binds to KRAS protein]]; SOS1 protein inhibits the reaction [Guanosine Diphosphate binds to KRAS protein]
Guanosine Diphosphate binds to KRAS protein; Guanosine Diphosphate binds to KRAS protein mutant form		 CTD PMID:28154176 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936 		JBrowse link
G PGP phosphoglycolate phosphatase decreases phosphorylation ISO PGP protein results in decreased phosphorylation of Guanosine Diphosphate CTD PMID:24338473 NCBI chr16:2,211,593...2,214,840
Ensembl chr16:2,211,593...2,214,840 		JBrowse link
G RAB3A RAB3A, member RAS oncogene family affects binding
multiple interactions		 ISO Guanosine Diphosphate binds to RAB3A protein
[alpha-latrotoxin promotes the reaction [RAB3A protein results in increased cleavage of Guanosine Triphosphate]] promotes the reaction [Guanosine Diphosphate binds to RAB3A protein]; [black widow spider venom promotes the reaction [RAB3A protein results in increased cleavage of Guanosine Triphosphate]] promotes the reaction [Guanosine Diphosphate binds to RAB3A protein]		 CTD PMID:7929154 NCBI chr19:18,196,784...18,204,042
Ensembl chr19:18,196,784...18,204,042 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 multiple interactions EXP [Enzyme Inhibitors binds to and results in decreased activity of SOS1 protein] promotes the reaction [HRAS protein binds to Guanosine Diphosphate]; Enzyme Inhibitors inhibits the reaction [SOS1 protein binds to [HRAS protein binds to Guanosine Diphosphate]]; KRAS protein mutant form inhibits the reaction [SOS1 protein inhibits the reaction [Guanosine Diphosphate binds to KRAS protein]]; SOS1 protein inhibits the reaction [Guanosine Diphosphate binds to KRAS protein] CTD PMID:25825487 PMID:28154176 NCBI chr 2:38,981,549...39,124,868
Ensembl chr 2:38,962,206...39,124,345 		JBrowse link
G TP53BP1 tumor protein p53 binding protein 1 multiple interactions EXP Guanosine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein] CTD PMID:32941855 NCBI chr15:43,403,061...43,510,640
Ensembl chr15:43,403,061...43,510,728 		JBrowse link
GDP-alpha-D-glucose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 increases abundance
multiple interactions		 ISO IDH2 protein mutant form results in increased abundance of guanosine diphosphate glucose
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of guanosine diphosphate glucose]		 CTD PMID:27469509 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477 		JBrowse link
GDP-beta-S term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT1 acetyl-CoA acetyltransferase 1 multiple interactions EXP guanosine 5'-O-(2-thiodiphosphate) inhibits the reaction [Serotonin results in increased expression of ACAT1 protein] CTD PMID:16157345 NCBI chr11:108,116,705...108,147,603
Ensembl chr11:108,116,695...108,147,603 		JBrowse link
G TRPC6 transient receptor potential cation channel subfamily C member 6 decreases activity ISO guanosine 5'-O-(2-thiodiphosphate) results in decreased activity of TRPC6 protein CTD PMID:11179201 NCBI chr11:101,451,564...101,584,007
Ensembl chr11:101,451,564...101,872,562 		JBrowse link
glutaryl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOT4 acyl-CoA thioesterase 4 affects hydrolysis ISO ACOT4 protein affects the hydrolysis of glutaryl-coenzyme A CTD PMID:16141203 NCBI chr14:73,591,873...73,595,766
Ensembl chr14:73,591,873...73,595,766 		JBrowse link
G ACOT8 acyl-CoA thioesterase 8 affects hydrolysis ISO ACOT8 protein affects the hydrolysis of glutaryl-coenzyme A CTD PMID:16141203 NCBI chr20:45,841,721...45,857,392
Ensembl chr20:45,841,721...45,857,405 		JBrowse link
GTP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 increases hydrolysis EXP ABCB1 protein results in increased hydrolysis of Guanosine Triphosphate CTD PMID:2900677 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G AHR aryl hydrocarbon receptor multiple interactions ISO Guanosine Triphosphate affects the folding of [Tetrachlorodibenzodioxin binds to AHR protein] CTD PMID:1848756 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G APP amyloid beta precursor protein increases secretion EXP Guanosine Triphosphate results in increased secretion of APP protein modified form CTD PMID:22906069 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G CDC42 cell division cycle 42 multiple interactions EXP
ISO		 Resveratrol promotes the reaction [CDC42 protein binds to Guanosine Triphosphate]; Risedronic Acid results in increased abundance of [Guanosine Triphosphate binds to CDC42 protein]; Zoledronic Acid results in increased expression of [CDC42 protein binds to Guanosine Triphosphate]
Ethanol results in decreased expression of [CDC42 protein binds to Guanosine Triphosphate]
Risedronic Acid results in increased abundance of [Guanosine Triphosphate binds to CDC42 protein]; Zoledronic Acid results in increased abundance of [Guanosine Triphosphate binds to CDC42 protein]		 CTD PMID:15217905 PMID:16734383 PMID:20829428 PMID:28871336 NCBI chr 1:22,052,709...22,101,360
Ensembl chr 1:22,052,627...22,101,360 		JBrowse link
G CRH corticotropin releasing hormone decreases activity ISO Guanosine Triphosphate results in decreased activity of CRH protein CTD PMID:2153673 NCBI chr 8:66,176,376...66,178,464
Ensembl chr 8:66,176,376...66,178,464 		JBrowse link
G CSF1 colony stimulating factor 1 multiple interactions ISO CSF1 protein results in increased abundance of [Guanosine Triphosphate binds to RAC1 protein]; Risedronic Acid promotes the reaction [CSF1 protein results in increased abundance of [Guanosine Triphosphate binds to RAC1 protein]] CTD PMID:16734383 NCBI chr 1:109,910,506...109,930,992
Ensembl chr 1:109,910,242...109,930,992 		JBrowse link
G FUT8 fucosyltransferase 8 decreases activity EXP Guanosine Triphosphate results in decreased activity of FUT8 protein CTD PMID:12770769 NCBI chr14:65,356,842...65,744,121
Ensembl chr14:65,410,592...65,744,121 		JBrowse link
G GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 multiple interactions EXP [dicyanocobinamide results in increased activity of [GUCY1A1 protein binds to GUCY1B1 protein]] which results in increased metabolism of Guanosine Triphosphate CTD PMID:22171090 NCBI chr 4:155,666,848...155,737,059
Ensembl chr 4:155,666,726...155,737,059 		JBrowse link
G GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 multiple interactions EXP [dicyanocobinamide results in increased activity of [GUCY1A1 protein binds to GUCY1B1 protein]] which results in increased metabolism of Guanosine Triphosphate CTD PMID:22171090 NCBI chr 4:155,759,021...155,807,811
Ensembl chr 4:155,758,992...155,807,811 		JBrowse link
G GYPA glycophorin A (MNS blood group) increases expression EXP Guanosine Triphosphate results in increased expression of GYPA protein CTD PMID:17002868 NCBI chr 4:144,109,303...144,140,718
Ensembl chr 4:144,109,303...144,140,751 		JBrowse link
G H2AX H2A.X variant histone multiple interactions EXP Guanosine Triphosphate inhibits the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form] CTD PMID:32941855 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465 		JBrowse link
G HRAS HRas proto-oncogene, GTPase multiple interactions EXP [Enzyme Inhibitors binds to and results in decreased activity of SOS1 protein] inhibits the reaction [HRAS protein binds to Guanosine Triphosphate] CTD PMID:25825487 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321 		JBrowse link
G HRH1 histamine receptor H1 multiple interactions EXP Guanosine Triphosphate analog affects the reaction [Histamine inhibits the reaction [Pyrilamine binds to HRH1 protein]] CTD PMID:2419744 NCBI chr 3:11,137,238...11,263,557
Ensembl chr 3:11,137,093...11,263,557 		JBrowse link
G HRH3 histamine receptor H3 multiple interactions
affects binding		 EXP
ISO		 6-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)-2H-pyridazin-3-one inhibits the reaction [alpha-methylhistamine promotes the reaction [Guanosine Triphosphate binds to HRH3 protein]]; alpha-methylhistamine promotes the reaction [Guanosine Triphosphate binds to HRH3 protein] CTD PMID:21634396 NCBI chr20:62,214,960...62,220,278
Ensembl chr20:62,214,960...62,220,278 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A multiple interactions ISO Guanosine Triphosphate affects the reaction [Serotonin binds to HTR1A protein]; Guanosine Triphosphate affects the reaction [Serotonin inhibits the reaction [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to HTR1A protein]]; Manganese inhibits the reaction [Guanosine Triphosphate affects the reaction [Serotonin binds to HTR1A protein]] CTD PMID:21126535 NCBI chr 5:63,957,874...63,962,445
Ensembl chr 5:63,957,874...63,962,507 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase affects binding
increases hydrolysis
multiple interactions		 EXP Guanosine Triphosphate binds to KRAS protein; Guanosine Triphosphate binds to KRAS protein mutant form
KRAS protein mutant form results in increased hydrolysis of Guanosine Triphosphate; KRAS protein results in increased hydrolysis of Guanosine Triphosphate
KRAS protein mutant form inhibits the reaction [RASA1 protein promotes the reaction [KRAS protein results in increased hydrolysis of Guanosine Triphosphate]]; RASA1 protein promotes the reaction [KRAS protein results in increased hydrolysis of Guanosine Triphosphate]		 CTD PMID:28154176 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 affects binding
multiple interactions		 EXP LRRK2 protein binds to Guanosine Triphosphate
sodium arsenite inhibits the reaction [LRRK2 protein binds to Guanosine Triphosphate]		 CTD PMID:24942733 NCBI chr12:40,224,997...40,369,285
Ensembl chr12:40,196,744...40,369,285 		JBrowse link
G MTNR1B melatonin receptor 1B multiple interactions EXP Guanosine Triphosphate inhibits the reaction [Carbaryl inhibits the reaction [Melatonin binds to MTNR1B protein]]; Guanosine Triphosphate inhibits the reaction [Carbofuran inhibits the reaction [Melatonin binds to MTNR1B protein]] CTD PMID:28027439 NCBI chr11:92,969,651...92,984,960
Ensembl chr11:92,969,651...92,985,066 		JBrowse link
G OPRM1 opioid receptor mu 1 affects binding
multiple interactions		 ISO Guanosine Triphosphate binds to OPRM1 protein
Dronabinol promotes the reaction [Guanosine Triphosphate binds to OPRM1 protein]		 CTD PMID:16823391 NCBI chr 6:154,010,496...154,246,867
Ensembl chr 6:154,010,496...154,246,867 		JBrowse link
G P2RX5 purinergic receptor P2X 5 affects transport ISO GTP affects transport ion flux of P2rx5 receptor RGD PMID:12237343 RGD:727431 NCBI chr17:3,673,227...3,696,155
Ensembl chr17:3,672,199...3,696,240 		JBrowse link
G P2RY4 pyrimidinergic receptor P2Y4 multiple interactions ISO Guanosine Triphosphate binds to and results in increased activity of P2RY4 protein CTD PMID:15654852 NCBI chr  X:70,258,166...70,260,204
Ensembl chr  X:70,258,166...70,260,204 		JBrowse link
G PANX1 pannexin 1 decreases activity ISO Guanosine Triphosphate results in decreased activity of PANX1 protein CTD PMID:19023039 NCBI chr11:94,128,841...94,181,968
Ensembl chr11:94,128,841...94,181,968 		JBrowse link
G PGP phosphoglycolate phosphatase decreases phosphorylation ISO PGP protein results in decreased phosphorylation of Guanosine Triphosphate CTD PMID:24338473 NCBI chr16:2,211,593...2,214,840
Ensembl chr16:2,211,593...2,214,840 		JBrowse link
G POMC proopiomelanocortin multiple interactions EXP
ISO		 [Guanosine Triphosphate co-treated with Lithium] results in decreased activity of POMC protein modified form; [Guanosine Triphosphate co-treated with Potassium] results in decreased activity of POMC protein modified form; [Guanosine Triphosphate co-treated with Sodium Chloride] results in decreased activity of POMC protein modified form CTD PMID:2550106 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903 		JBrowse link
G RAB3A RAB3A, member RAS oncogene family affects binding
increases cleavage
multiple interactions		 ISO [RAB3A protein binds to Guanosine Triphosphate] which binds to RABGAP1 protein; Guanosine Triphosphate binds to RAB3A protein; RAB3A protein binds to Guanosine Triphosphate; SNCA protein binds to [RAB3A protein binds to Guanosine Triphosphate]
RAB3A protein results in increased cleavage of Guanosine Triphosphate
[alpha-latrotoxin promotes the reaction [RAB3A protein results in increased cleavage of Guanosine Triphosphate]] promotes the reaction [Guanosine Diphosphate binds to RAB3A protein]; [black widow spider venom promotes the reaction [RAB3A protein results in increased cleavage of Guanosine Triphosphate]] promotes the reaction [Guanosine Diphosphate binds to RAB3A protein]; manganese chloride inhibits the reaction [[RAB3A protein binds to Guanosine Triphosphate] which binds to RABGAP1 protein]; manganese chloride promotes the reaction [SNCA protein binds to [RAB3A protein binds to Guanosine Triphosphate]]; manganese chloride results in increased expression of [RAB3A protein binds to Guanosine Triphosphate]; SNCA protein promotes the reaction [manganese chloride inhibits the reaction [[RAB3A protein binds to Guanosine Triphosphate] which binds to RABGAP1 protein]]		 CTD PMID:7929154 PMID:29289693 NCBI chr19:18,196,784...18,204,042
Ensembl chr19:18,196,784...18,204,042 		JBrowse link
G RABGAP1 RAB GTPase activating protein 1 affects binding
multiple interactions		 ISO [RAB3A protein binds to Guanosine Triphosphate] which binds to RABGAP1 protein
manganese chloride inhibits the reaction [[RAB3A protein binds to Guanosine Triphosphate] which binds to RABGAP1 protein]; SNCA protein promotes the reaction [manganese chloride inhibits the reaction [[RAB3A protein binds to Guanosine Triphosphate] which binds to RABGAP1 protein]]		 CTD PMID:29289693 NCBI chr 9:122,931,671...123,104,866
Ensembl chr 9:122,940,833...123,104,866 		JBrowse link
G RAC1 Rac family small GTPase 1 multiple interactions EXP
ISO		 Risedronic Acid results in increased abundance of [Guanosine Triphosphate binds to RAC1 protein]; Zoledronic Acid results in increased expression of [RAC1 protein binds to Guanosine Triphosphate]
Ethanol results in decreased expression of [RAC1 protein binds to Guanosine Triphosphate]
CSF1 protein results in increased abundance of [Guanosine Triphosphate binds to RAC1 protein]; GGTI 298 results in increased abundance of [Guanosine Triphosphate binds to RAC1 protein]; mevastatin results in increased abundance of [Guanosine Triphosphate binds to RAC1 protein]; Risedronic Acid promotes the reaction [CSF1 protein results in increased abundance of [Guanosine Triphosphate binds to RAC1 protein]]; Risedronic Acid results in increased abundance of [Guanosine Triphosphate binds to RAC1 protein]; Zoledronic Acid results in increased abundance of [Guanosine Triphosphate binds to RAC1 protein]		 CTD PMID:16734383 PMID:20829428 PMID:28871336 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967 		JBrowse link
G RAP1B RAP1B, member of RAS oncogene family multiple interactions EXP
ISO		 [Pentoxifylline results in increased abundance of Cyclic AMP] results in increased abundance of [RAP1B protein binds to Guanosine Triphosphate] CTD PMID:21693435 NCBI chr12:68,610,899...68,671,901
Ensembl chr12:68,610,855...68,671,901 		JBrowse link
G RASA1 RAS p21 protein activator 1 multiple interactions EXP KRAS protein mutant form inhibits the reaction [RASA1 protein promotes the reaction [KRAS protein results in increased hydrolysis of Guanosine Triphosphate]]; RASA1 protein promotes the reaction [KRAS protein results in increased hydrolysis of Guanosine Triphosphate] CTD PMID:28154176 NCBI chr 5:87,267,883...87,391,916
Ensembl chr 5:87,267,883...87,391,931 		JBrowse link
G RHOA ras homolog family member A multiple interactions
affects binding		 ISO
EXP		 Dronabinol inhibits the reaction [Guanosine Triphosphate binds to and results in increased activity of RHOA protein]; Guanosine Triphosphate binds to and results in increased activity of RHOA protein; Risedronic Acid results in increased abundance of [Guanosine Triphosphate binds to RHOA protein]; Zoledronic Acid results in increased abundance of [Guanosine Triphosphate binds to RHOA protein]
Asbestos, Crocidolite inhibits the reaction [RHOA protein binds to Guanosine Triphosphate]; Cadmium Chloride promotes the reaction [RHOA protein binds to Guanosine Triphosphate]; Dronabinol inhibits the reaction [Guanosine Triphosphate binds to and results in increased activity of RHOA protein]; Guanosine Triphosphate binds to and results in increased activity of RHOA protein; Risedronic Acid results in increased abundance of [Guanosine Triphosphate binds to RHOA protein]; tempol inhibits the reaction [Asbestos, Crocidolite inhibits the reaction [RHOA protein binds to Guanosine Triphosphate]]; tempol inhibits the reaction [Vitamin K 3 inhibits the reaction [RHOA protein binds to Guanosine Triphosphate]]; Vitamin K 3 inhibits the reaction [RHOA protein binds to Guanosine Triphosphate]; Zoledronic Acid results in increased expression of [RHOA protein binds to Guanosine Triphosphate]		 CTD PMID:16734383 PMID:21257924 PMID:26220685 PMID:28871336 PMID:29307655 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998 		JBrowse link
G SNCA synuclein alpha multiple interactions
affects binding		 ISO manganese chloride promotes the reaction [SNCA protein binds to [RAB3A protein binds to Guanosine Triphosphate]]; SNCA protein promotes the reaction [manganese chloride inhibits the reaction [[RAB3A protein binds to Guanosine Triphosphate] which binds to RABGAP1 protein]] CTD PMID:29289693 NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 multiple interactions EXP [Enzyme Inhibitors binds to and results in decreased activity of SOS1 protein] inhibits the reaction [HRAS protein binds to Guanosine Triphosphate] CTD PMID:25825487 NCBI chr 2:38,981,549...39,124,868
Ensembl chr 2:38,962,206...39,124,345 		JBrowse link
G TGM2 transglutaminase 2 affects binding EXP Guanosine Triphosphate binds to TGM2 protein CTD PMID:15556610 NCBI chr20:38,127,385...38,168,475
Ensembl chr20:38,127,385...38,166,578 		JBrowse link
G TP53BP1 tumor protein p53 binding protein 1 multiple interactions EXP Guanosine Triphosphate inhibits the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein] CTD PMID:32941855 NCBI chr15:43,403,061...43,510,640
Ensembl chr15:43,403,061...43,510,728 		JBrowse link
guanosine 5'-[gamma-thio]triphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2A adenosine A2a receptor multiple interactions ISO ADORA2A protein affects the reaction [[Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to OPRM1 protein] which results in increased activity of Guanosine 5'-O-(3-Thiotriphosphate)] CTD PMID:14756803 NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357 		JBrowse link
G CNR1 cannabinoid receptor 1 multiple interactions
affects binding		 EXP (1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone metabolite promotes the reaction [CNR1 protein binds to Guanosine 5'-O-(3-Thiotriphosphate)]; (1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone promotes the reaction [CNR1 protein binds to Guanosine 5'-O-(3-Thiotriphosphate)]; 1-pentyl-1H-indole-3-carboxylic acid 8-quinolinyl ester promotes the reaction [CNR1 protein binds to Guanosine 5'-O-(3-Thiotriphosphate)]; 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol promotes the reaction [CNR1 protein binds to Guanosine 5'-O-(3-Thiotriphosphate)]; 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR1 protein]; 5F-CUMYL-PICA promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR1 protein]; AM 6527 promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR1 protein]; delta(9)-tetrahydrocannabinolic acid promotes the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR1 protein]]; delta(9)-tetrahydrocannabinolic acid promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR1 protein]; Dronabinol promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR1 protein]; methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3-methylbutanoate analog promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR1 protein]; methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3-methylbutanoate promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR1 protein]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR1 protein]; XLR-11 metabolite promotes the reaction [CNR1 protein binds to Guanosine 5'-O-(3-Thiotriphosphate)]; XLR-11 promotes the reaction [CNR1 protein binds to Guanosine 5'-O-(3-Thiotriphosphate)] CTD PMID:28087785 PMID:29549157 PMID:32510591 NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347 		JBrowse link
G CNR2 cannabinoid receptor 2 affects binding
multiple interactions		 EXP Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR2 protein
(1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone metabolite promotes the reaction [CNR2 protein binds to Guanosine 5'-O-(3-Thiotriphosphate)]; (1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone promotes the reaction [CNR2 protein binds to Guanosine 5'-O-(3-Thiotriphosphate)]; 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol promotes the reaction [CNR2 protein binds to Guanosine 5'-O-(3-Thiotriphosphate)]; 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR2 protein]; 4-hydroxy-N-desmethyltamoxifen inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR2 protein]; 5F-CUMYL-PICA promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR2 protein]; afimoxifene inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR2 protein]; AM 281 inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR2 protein]; AM 6527 promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR2 protein]; cannabinoid CB2 receptor agonist ABK5 promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR2 protein]; delta(9)-tetrahydrocannabinolic acid inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR2 protein]; Dronabinol promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR2 protein]; iodopravadoline inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR2 protein]; methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3-methylbutanoate analog promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR2 protein]; methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3-methylbutanoate promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR2 protein]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR2 protein]; ridaifen-B inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR2 protein]; Tamoxifen inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to CNR2 protein]; XLR-11 metabolite promotes the reaction [CNR2 protein binds to Guanosine 5'-O-(3-Thiotriphosphate)]; XLR-11 promotes the reaction [CNR2 protein binds to Guanosine 5'-O-(3-Thiotriphosphate)]		 CTD PMID:27936172 PMID:28087785 PMID:29549157 PMID:29906493 PMID:30951717 More... NCBI chr 1:23,870,515...23,913,362
Ensembl chr 1:23,870,515...23,913,362 		JBrowse link
G GNA13 G protein subunit alpha 13 affects binding
multiple interactions		 EXP Guanosine 5'-O-(3-Thiotriphosphate) binds to GNA13 protein
[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of GPR55 protein] affects the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to GNA13 protein]		 CTD PMID:17876302 NCBI chr17:65,009,289...65,056,740
Ensembl chr17:65,009,289...65,056,740 		JBrowse link
G GNAI1 G protein subunit alpha i1 affects binding ISO GNAI1 protein binds to Guanosine 5'-O-(3-Thiotriphosphate) CTD PMID:29748632 NCBI chr 7:80,134,831...80,226,181
Ensembl chr 7:79,768,028...80,226,181 		JBrowse link
G GNAI3 G protein subunit alpha i3 affects binding ISO GNAI3 protein binds to Guanosine 5'-O-(3-Thiotriphosphate) CTD PMID:29748632 NCBI chr 1:109,548,615...109,600,195
Ensembl chr 1:109,548,615...109,600,195 		JBrowse link
G GNAO1 G protein subunit alpha o1 affects binding ISO GNAO1 protein binds to Guanosine 5'-O-(3-Thiotriphosphate) CTD PMID:29748632 NCBI chr16:56,191,489...56,357,444
Ensembl chr16:56,191,390...56,357,444 		JBrowse link
G GNAS GNAS complex locus affects binding ISO GNAS protein binds to Guanosine 5'-O-(3-Thiotriphosphate) CTD PMID:29748632 NCBI chr20:58,839,748...58,911,192
Ensembl chr20:58,839,718...58,911,192 		JBrowse link
G GNAZ G protein subunit alpha z affects binding ISO GNAZ protein binds to Guanosine 5'-O-(3-Thiotriphosphate) CTD PMID:29748632 NCBI chr22:23,070,519...23,125,032
Ensembl chr22:23,070,519...23,125,032 		JBrowse link
G GPR55 G protein-coupled receptor 55 multiple interactions EXP [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of GPR55 protein] affects the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to GNA13 protein] CTD PMID:17876302 NCBI chr 2:230,907,328...230,961,201
Ensembl chr 2:230,907,318...230,961,066 		JBrowse link
G HRH4 histamine receptor H4 affects binding
multiple interactions		 EXP Guanosine 5'-O-(3-Thiotriphosphate) binds to HRH4 protein
Histamine promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to HRH4 protein]		 CTD PMID:11181941 NCBI chr18:24,460,637...24,479,974
Ensembl chr18:24,460,637...24,479,961 		JBrowse link
G MYL9 myosin light chain 9 multiple interactions ISO [Escin affects the susceptibility to Guanosine 5'-O-(3-Thiotriphosphate)] which results in increased phosphorylation of MYL9 protein; Glycodeoxycholic Acid inhibits the reaction [[Escin affects the susceptibility to Guanosine 5'-O-(3-Thiotriphosphate)] which results in increased phosphorylation of MYL9 protein]; Y 27632 inhibits the reaction [[Escin affects the susceptibility to Guanosine 5'-O-(3-Thiotriphosphate)] which results in increased phosphorylation of MYL9 protein] CTD PMID:29660437 NCBI chr20:36,541,519...36,551,447
Ensembl chr20:36,541,497...36,551,447 		JBrowse link
G OPRM1 opioid receptor mu 1 multiple interactions EXP
ISO		 [7-benzylidenenaltrexone binds to and results in decreased activity of OPRM1 protein] which affects the localization of Guanosine 5'-O-(3-Thiotriphosphate); [chlornaltrexamine binds to and results in decreased activity of OPRM1 protein] which affects the localization of Guanosine 5'-O-(3-Thiotriphosphate); [clocinnamox binds to and results in decreased activity of OPRM1 protein] which affects the localization of Guanosine 5'-O-(3-Thiotriphosphate)
[Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to OPRM1 protein] which results in increased activity of Guanosine 5'-O-(3-Thiotriphosphate); ADORA2A protein affects the reaction [[Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to OPRM1 protein] which results in increased activity of Guanosine 5'-O-(3-Thiotriphosphate)]		 CTD PMID:11413242 PMID:14756803 NCBI chr 6:154,010,496...154,246,867
Ensembl chr 6:154,010,496...154,246,867 		JBrowse link
G PLCB1 phospholipase C beta 1 multiple interactions
increases activity		 ISO [3,4-dihydroxyphenylglycol co-treated with Guanosine 5'-O-(3-Thiotriphosphate)] results in increased activity of PLCB1 protein; Caffeine inhibits the reaction [[3,4-dihydroxyphenylglycol co-treated with Guanosine 5'-O-(3-Thiotriphosphate)] results in increased activity of PLCB1 protein]; Caffeine inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) results in increased activity of PLCB1 protein]; Theophylline inhibits the reaction [[3,4-dihydroxyphenylglycol co-treated with Guanosine 5'-O-(3-Thiotriphosphate)] results in increased activity of PLCB1 protein]; Theophylline inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) results in increased activity of PLCB1 protein] CTD PMID:15998294 NCBI chr20:8,132,266...8,884,900
Ensembl chr20:8,077,251...8,968,360 		JBrowse link
G PLCG2 phospholipase C gamma 2 multiple interactions EXP [[RAC2 protein co-treated with Guanosine 5'-O-(3-Thiotriphosphate)] results in increased activity of PLCG2 protein] which results in increased chemical synthesis of Inositol Phosphates; [Guanosine 5'-O-(3-Thiotriphosphate) co-treated with RAC2 protein] promotes the reaction [PLCG2 protein mutant form results in increased chemical synthesis of Inositol Phosphates]; [Guanosine 5'-O-(3-Thiotriphosphate) co-treated with RAC2 protein] promotes the reaction [PLCG2 protein results in increased chemical synthesis of Inositol Phosphates]; [RAC2 protein co-treated with Guanosine 5'-O-(3-Thiotriphosphate)] results in increased activity of PLCG2 protein; PLCG2 protein mutant form results in decreased susceptibility to [RAC2 protein co-treated with Guanosine 5'-O-(3-Thiotriphosphate)] CTD PMID:25903139 PMID:27542411 NCBI chr16:81,779,291...81,962,685
Ensembl chr16:81,779,279...81,962,685 		JBrowse link
G PLEK pleckstrin increases phosphorylation
multiple interactions		 EXP Guanosine 5'-O-(3-Thiotriphosphate) results in increased phosphorylation of PLEK protein
dioleoylphosphatidic acid analog promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) results in increased phosphorylation of PLEK protein]; Oleic Acid promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) results in increased phosphorylation of PLEK protein]; phosphatidylethanol analog promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) results in increased phosphorylation of PLEK protein]		 CTD PMID:8928743 NCBI chr 2:68,365,282...68,397,453
Ensembl chr 2:68,365,282...68,397,453 		JBrowse link
G PPP1R12A protein phosphatase 1 regulatory subunit 12A increases phosphorylation
multiple interactions		 ISO Guanosine 5'-O-(3-Thiotriphosphate) results in increased phosphorylation of PPP1R12A protein
Guanosine 5'-O-(3-Thiotriphosphate) inhibits the reaction [15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid results in increased phosphorylation of PPP1R12A protein]		 CTD PMID:29660437 NCBI chr12:79,773,563...79,935,460
Ensembl chr12:79,773,563...79,935,460 		JBrowse link
G PTGDR prostaglandin D2 receptor multiple interactions EXP Guanosine 5'-O-(3-Thiotriphosphate) inhibits the reaction [Prostaglandin D2 binds to PTGDR protein] CTD PMID:9579725 NCBI chr14:52,267,698...52,280,914
Ensembl chr14:52,267,698...52,276,724 		JBrowse link
G RAC1 Rac family small GTPase 1 multiple interactions EXP Methohexital inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) results in increased activity of RAC1 protein]; Pentobarbital inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) results in increased activity of RAC1 protein]; Secobarbital inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) results in increased activity of RAC1 protein]; Thiamylal inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) results in increased activity of RAC1 protein] CTD PMID:15263067 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967 		JBrowse link
G RAC2 Rac family small GTPase 2 multiple interactions EXP [[RAC2 protein co-treated with Guanosine 5'-O-(3-Thiotriphosphate)] results in increased activity of PLCG2 protein] which results in increased chemical synthesis of Inositol Phosphates; [Guanosine 5'-O-(3-Thiotriphosphate) co-treated with RAC2 protein] promotes the reaction [PLCG2 protein mutant form results in increased chemical synthesis of Inositol Phosphates]; [Guanosine 5'-O-(3-Thiotriphosphate) co-treated with RAC2 protein] promotes the reaction [PLCG2 protein results in increased chemical synthesis of Inositol Phosphates]; [RAC2 protein co-treated with Guanosine 5'-O-(3-Thiotriphosphate)] results in increased activity of PLCG2 protein; PLCG2 protein mutant form results in decreased susceptibility to [RAC2 protein co-treated with Guanosine 5'-O-(3-Thiotriphosphate)] CTD PMID:25903139 PMID:27542411 NCBI chr22:37,225,270...37,244,269
Ensembl chr22:37,225,270...37,259,594 		JBrowse link
G RHOA ras homolog family member A affects localization
multiple interactions		 ISO Guanosine 5'-O-(3-Thiotriphosphate) affects the localization of RHOA protein
[Escin affects the susceptibility to Guanosine 5'-O-(3-Thiotriphosphate)] which results in increased localization of RHOA protein; Glycodeoxycholic Acid inhibits the reaction [[Escin affects the susceptibility to Guanosine 5'-O-(3-Thiotriphosphate)] which results in increased localization of RHOA protein]; Sevoflurane inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) affects the localization of RHOA protein]		 CTD PMID:12960549 PMID:29660437 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998 		JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 affects localization
multiple interactions		 ISO Guanosine 5'-O-(3-Thiotriphosphate) affects the localization of ROCK2 protein
sevoflurane inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) affects the localization of ROCK2 protein]		 CTD PMID:12960549 NCBI chr 2:11,179,759...11,345,437
Ensembl chr 2:11,179,759...11,348,330 		JBrowse link
G TRPC6 transient receptor potential cation channel subfamily C member 6 increases activity ISO Guanosine 5'-O-(3-Thiotriphosphate) results in increased activity of TRPC6 protein CTD PMID:11179201 NCBI chr11:101,451,564...101,584,007
Ensembl chr11:101,451,564...101,872,562 		JBrowse link
guanosine 5'-monophosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FUT8 fucosyltransferase 8 decreases activity EXP Guanosine Monophosphate results in decreased activity of FUT8 protein CTD PMID:12770769 NCBI chr14:65,356,842...65,744,121
Ensembl chr14:65,410,592...65,744,121 		JBrowse link
G GMDS GDP-mannose 4,6-dehydratase affects binding EXP Guanosine Monophosphate binds to GMDS protein CTD PMID:25526675 NCBI chr 6:1,623,806...2,245,605
Ensembl chr 6:1,623,806...2,245,605 		JBrowse link
hexanoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PECR peroxisomal trans-2-enoyl-CoA reductase multiple interactions EXP [hexanoyl-coenzyme A co-treated with NADP] binds to PECR protein CTD PMID:25526675 NCBI chr 2:216,029,088...216,081,809
Ensembl chr 2:215,996,329...216,082,955 		JBrowse link
IDP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G H2AX H2A.X variant histone multiple interactions EXP Inosine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form] CTD PMID:32941855 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465 		JBrowse link
G TP53BP1 tumor protein p53 binding protein 1 multiple interactions EXP Inosine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein] CTD PMID:32941855 NCBI chr15:43,403,061...43,510,640
Ensembl chr15:43,403,061...43,510,728 		JBrowse link
IMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL1B interleukin 1 beta multiple interactions ISO [Inosine Monophosphate co-treated with potassium oxonate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; SCH 442416 inhibits the reaction [Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]] CTD PMID:20868668 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IMPDH2 inosine monophosphate dehydrogenase 2 multiple interactions
affects binding		 EXP berberrubine inhibits the reaction [Inosine Monophosphate binds to IMPDH2 protein] CTD PMID:37871880 NCBI chr 3:49,024,325...49,029,398
Ensembl chr 3:49,024,325...49,029,447 		JBrowse link
G MPO myeloperoxidase multiple interactions ISO [potassium oxonate co-treated with Inosine Monophosphate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; SCH 442416 inhibits the reaction [Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]] CTD PMID:20868668 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO [Inosine Monophosphate co-treated with potassium oxonate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; SCH 442416 inhibits the reaction [Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]] CTD PMID:20868668 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TP73 tumor protein p73 affects abundance ISO TP73 protein affects the abundance of Inosine Monophosphate CTD PMID:25554796 NCBI chr 1:3,652,516...3,736,201
Ensembl chr 1:3,652,516...3,736,201 		JBrowse link
isobutyryl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KAT2B lysine acetyltransferase 2B affects binding ISO isobutyryl-coenzyme A binds to KAT2B protein CTD PMID:28077572 NCBI chr 3:20,040,446...20,154,404
Ensembl chr 3:20,040,446...20,154,404 		JBrowse link
lauroyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSTA1 glutathione S-transferase alpha 1 multiple interactions EXP lauroyl-coenzyme A binds to and results in decreased activity of GSTA1 protein CTD PMID:10542059 NCBI chr 6:52,791,371...52,803,816
Ensembl chr 6:52,791,371...52,803,860 		JBrowse link
G HSDL2 hydroxysteroid dehydrogenase like 2 multiple interactions EXP [lauroyl-coenzyme A co-treated with NADP] binds to HSDL2 protein CTD PMID:25526675 NCBI chr 9:112,380,108...112,472,405
Ensembl chr 9:112,380,080...112,472,405 		JBrowse link
G PECR peroxisomal trans-2-enoyl-CoA reductase multiple interactions EXP [lauroyl-coenzyme A co-treated with NADP] binds to PECR protein CTD PMID:25526675 NCBI chr 2:216,029,088...216,081,809
Ensembl chr 2:215,996,329...216,082,955 		JBrowse link
malonyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MLYCD malonyl-CoA decarboxylase multiple interactions ISO PPARA protein promotes the reaction [MLYCD protein results in decreased abundance of Malonyl Coenzyme A] CTD PMID:14641110 NCBI chr16:83,899,115...83,927,031
Ensembl chr16:83,899,115...83,951,445 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions ISO PPARA protein promotes the reaction [MLYCD protein results in decreased abundance of Malonyl Coenzyme A] CTD PMID:14641110 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
methacrylyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ECHS1 enoyl-CoA hydratase, short chain 1 increases abundance EXP ECHS1 gene mutant form results in increased abundance of methacrylyl-coenzyme A CTD PMID:25125611 NCBI chr10:133,362,485...133,373,354
Ensembl chr10:133,362,485...133,373,354 		JBrowse link
G HIBCH 3-hydroxyisobutyryl-CoA hydrolase increases abundance EXP HIBCH gene mutant form results in increased abundance of methacrylyl-coenzyme A CTD PMID:25125611 NCBI chr 2:190,189,735...190,319,826
Ensembl chr 2:190,189,735...190,344,193 		JBrowse link
myristoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DBI diazepam binding inhibitor, acyl-CoA binding protein affects binding EXP S-tetradecanoyl-coenzyme A binds to DBI protein CTD PMID:17044054 NCBI chr 2:119,366,977...119,372,543
Ensembl chr 2:119,366,924...119,372,550 		JBrowse link
G GSTA1 glutathione S-transferase alpha 1 multiple interactions EXP S-tetradecanoyl-coenzyme A binds to and results in decreased activity of GSTA1 protein CTD PMID:10542059 NCBI chr 6:52,791,371...52,803,816
Ensembl chr 6:52,791,371...52,803,860 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions EXP S-tetradecanoyl-coenzyme A binds to and results in increased activity of PPARA protein CTD PMID:11139385 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
N(6)-butyryl-cAMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AR androgen receptor multiple interactions ISO [monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of AR mRNA; naphthol AS-E phosphate inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of AR mRNA] CTD PMID:18467523 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions ISO [monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of CREB1 protein CTD PMID:18467523 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988 		JBrowse link
G CREM cAMP responsive element modulator multiple interactions
increases expression
decreases response to substance		 ISO CREM protein inhibits the reaction [monobutyryl cyclic AMP results in increased activity of HIF1A protein]; CREM protein inhibits the reaction [monobutyryl cyclic AMP results in increased expression of IRS2 mRNA]; CREM protein inhibits the reaction [monobutyryl cyclic AMP results in increased expression of NR4A2 mRNA]; CREM protein inhibits the reaction [monobutyryl cyclic AMP results in increased expression of PPARGC1A mRNA]; CREM protein inhibits the reaction [monobutyryl cyclic AMP results in increased expression of VEGFA protein]
monobutyryl cyclic AMP results in increased expression of CREM mRNA
CREM protein results in decreased susceptibility to monobutyryl cyclic AMP		 CTD PMID:25381014 NCBI chr10:35,126,846...35,212,958
Ensembl chr10:35,126,791...35,212,958 		JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 multiple interactions ISO [monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP51 mRNA; [monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP51 protein; naphthol AS-E phosphate inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP51 mRNA]; naphthol AS-E phosphate inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP51 protein] CTD PMID:18467523 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803 		JBrowse link
G EGF epidermal growth factor multiple interactions ISO EGF protein inhibits the reaction [naphthol AS-E phosphate inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; EGF protein inhibits the reaction [naphthol AS-E phosphate inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of and results in increased activity of MAPK3 protein]] CTD PMID:18467523 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions ISO CREM protein inhibits the reaction [monobutyryl cyclic AMP results in increased activity of HIF1A protein]; monobutyryl cyclic AMP results in increased expression of and affects the localization of and results in increased activity of HIF1A protein CTD PMID:25381014 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G IRS2 insulin receptor substrate 2 increases expression
multiple interactions		 ISO monobutyryl cyclic AMP results in increased expression of IRS2 mRNA
CREM protein inhibits the reaction [monobutyryl cyclic AMP results in increased expression of IRS2 mRNA]		 CTD PMID:25381014 NCBI chr13:109,752,695...109,786,583
Ensembl chr13:109,752,695...109,786,583 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions ISO [monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of and results in increased activity of MAPK1 protein; azalanstat inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; EGF protein inhibits the reaction [naphthol AS-E phosphate inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; naphthol AS-E phosphate inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of and results in increased activity of MAPK1 protein] CTD PMID:18467523 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO [monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of and results in increased activity of MAPK3 protein; azalanstat inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; EGF protein inhibits the reaction [naphthol AS-E phosphate inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; naphthol AS-E phosphate inhibits the reaction [[monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:18467523 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G NR4A2 nuclear receptor subfamily 4 group A member 2 increases expression
multiple interactions		 ISO monobutyryl cyclic AMP results in increased expression of NR4A2 mRNA
CREM protein inhibits the reaction [monobutyryl cyclic AMP results in increased expression of NR4A2 mRNA]		 CTD PMID:25381014 NCBI chr 2:156,324,437...156,332,721
Ensembl chr 2:156,324,437...156,342,348 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha increases expression
multiple interactions		 ISO monobutyryl cyclic AMP results in increased expression of PPARGC1A mRNA
CREM protein inhibits the reaction [monobutyryl cyclic AMP results in increased expression of PPARGC1A mRNA]		 CTD PMID:25381014 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G PRKAR2B protein kinase cAMP-dependent type II regulatory subunit beta multiple interactions ISO [monobutyryl cyclic AMP co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of PRKAR2B protein CTD PMID:18467523 NCBI chr 7:107,044,705...107,161,811
Ensembl chr 7:107,044,705...107,161,811 		JBrowse link
G RPS6 ribosomal protein S6 increases expression ISO monobutyryl cyclic AMP results in increased expression of RPS6 protein modified form CTD PMID:25381014 NCBI chr 9:19,375,715...19,380,236
Ensembl chr 9:19,375,715...19,380,236 		JBrowse link
G VEGFA vascular endothelial growth factor A increases expression
multiple interactions		 ISO monobutyryl cyclic AMP results in increased expression of VEGFA protein
CREM protein inhibits the reaction [monobutyryl cyclic AMP results in increased expression of VEGFA protein]		 CTD PMID:25381014 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
NMN zwitterion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACADM acyl-CoA dehydrogenase medium chain multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [MIR34A mRNA results in decreased expression of ACADM mRNA] CTD PMID:23834033 NCBI chr 1:75,724,709...75,763,679
Ensembl chr 1:75,724,431...75,787,575 		JBrowse link
G ACP5 acid phosphatase 5, tartrate resistant multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of ACP5 protein] CTD PMID:30292833 NCBI chr19:11,574,660...11,578,975
Ensembl chr19:11,574,653...11,579,993 		JBrowse link
G AXIN1 axin 1 multiple interactions EXP Nicotinamide Mononucleotide inhibits the reaction [N-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(pyridin-3-yl)acrylamide results in increased expression of AXIN1 protein] CTD PMID:32005247 NCBI chr16:287,440...352,723
Ensembl chr16:287,440...352,723 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in decreased expression of BGLAP protein]
Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in decreased activity of BGLAP protein]; Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in decreased expression of BGLAP protein]		 CTD PMID:30292833 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317 		JBrowse link
G CASP1 caspase 1 multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of CASP1 protein modified form] CTD PMID:30292833 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CCND1 cyclin D1 multiple interactions EXP Nicotinamide Mononucleotide affects the reaction [NAMPT protein affects the expression of CCND1 protein]; Nicotinamide Mononucleotide inhibits the reaction [N-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(pyridin-3-yl)acrylamide results in decreased expression of CCND1 protein] CTD PMID:32005247 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CTNNB1 catenin beta 1 multiple interactions EXP Nicotinamide Mononucleotide affects the reaction [NAMPT protein affects the expression of CTNNB1 protein]; Nicotinamide Mononucleotide inhibits the reaction [N-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(pyridin-3-yl)acrylamide results in decreased expression of CTNNB1 protein] CTD PMID:32005247 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor decreases abundance EXP ERCC6 gene mutant form results in decreased abundance of Nicotinamide Mononucleotide CTD PMID:25440059 NCBI chr10:49,434,881...49,539,538
Ensembl chr10:49,454,168...49,539,538 		JBrowse link
G FOXO4 forkhead box O4 multiple interactions EXP Nicotinamide Mononucleotide inhibits the reaction [[NNT protein inhibits the reaction [NNT protein modified form results in decreased susceptibility to Cisplatin]] which results in decreased expression of FOXO4 mRNA] CTD PMID:36336710 NCBI chr  X:71,095,851...71,103,532
Ensembl chr  X:71,095,851...71,103,532 		JBrowse link
G GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 increases expression EXP Nicotinamide Mononucleotide results in increased expression of GALNT1 mRNA CTD PMID:29935245 NCBI chr18:35,580,922...35,711,834
Ensembl chr18:35,581,117...35,711,834 		JBrowse link
G GLB1 galactosidase beta 1 multiple interactions ISO [resveratrol co-treated with Nicotinamide Mononucleotide] inhibits the reaction [RETN protein results in increased activity of GLB1 protein] CTD PMID:23827175 NCBI chr 3:32,961,108...33,097,146
Ensembl chr 3:32,996,609...33,097,202 		JBrowse link
G H2AX H2A.X variant histone multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of H2AX protein] CTD PMID:36756972 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465 		JBrowse link
G IL18 interleukin 18 multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of IL18 protein] CTD PMID:30292833 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of IL1B protein] CTD PMID:30292833 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G MIR34A microRNA 34a multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [MIR34A mRNA inhibits the reaction [NAMPT protein results in increased chemical synthesis of NAD]]; Nicotinamide Mononucleotide inhibits the reaction [MIR34A mRNA results in decreased abundance of NAD]; Nicotinamide Mononucleotide inhibits the reaction [MIR34A mRNA results in decreased expression of ACADM mRNA]; Nicotinamide Mononucleotide inhibits the reaction [MIR34A mRNA results in decreased expression of PPARA mRNA]; Nicotinamide Mononucleotide inhibits the reaction [MIR34A mRNA results in decreased expression of PPARD mRNA] CTD PMID:23834033 NCBI chr 1:9,151,668...9,151,777
Ensembl chr 1:9,151,668...9,151,777 		JBrowse link
G NAMPT nicotinamide phosphoribosyltransferase affects binding
multiple interactions		 ISO
EXP		 NAMPT protein binds to Nicotinamide Mononucleotide
Nicotinamide Mononucleotide affects the reaction [NAMPT protein affects the expression of CCND1 protein]; Nicotinamide Mononucleotide affects the reaction [NAMPT protein affects the expression of CTNNB1 protein]
Nicotinamide Mononucleotide inhibits the reaction [MIR34A mRNA inhibits the reaction [NAMPT protein results in increased chemical synthesis of NAD]]		 CTD PMID:16901503 PMID:23834033 PMID:32005247 NCBI chr 7:106,248,298...106,285,888
Ensembl chr 7:106,248,298...106,285,966 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of NLRP3 protein]
Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of NLRP3 mRNA]; Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of NLRP3 protein]		 CTD PMID:30292833 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108 		JBrowse link
G NNT nicotinamide nucleotide transhydrogenase multiple interactions EXP 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Nicotinamide Mononucleotide inhibits the reaction [[NNT protein inhibits the reaction [NNT protein modified form results in decreased susceptibility to Cisplatin]] which results in increased expression of SQSTM1 protein]]; Nicotinamide Mononucleotide inhibits the reaction [[NNT protein inhibits the reaction [NNT protein modified form results in decreased susceptibility to Cisplatin]] which results in decreased expression of FOXO4 mRNA]; Nicotinamide Mononucleotide inhibits the reaction [[NNT protein inhibits the reaction [NNT protein modified form results in decreased susceptibility to Cisplatin]] which results in decreased expression of PPARGC1A mRNA]; Nicotinamide Mononucleotide inhibits the reaction [[NNT protein inhibits the reaction [NNT protein modified form results in decreased susceptibility to Cisplatin]] which results in decreased expression of SHANK2 mRNA]; Nicotinamide Mononucleotide inhibits the reaction [[NNT protein inhibits the reaction [NNT protein modified form results in decreased susceptibility to Cisplatin]] which results in increased expression of SQSTM1 protein] CTD PMID:36336710 NCBI chr 5:43,602,675...43,707,396
Ensembl chr 5:43,602,692...43,707,405 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 affects abundance
multiple interactions		 EXP
ISO		 PARP1 protein affects the abundance of Nicotinamide Mononucleotide
[Nicotinamide Mononucleotide co-treated with Cisplatin] results in decreased expression of PARP1 protein		 CTD PMID:19426698 PMID:34089817 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [MIR34A mRNA results in decreased expression of PPARA mRNA] CTD PMID:23834033 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARD peroxisome proliferator activated receptor delta multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [MIR34A mRNA results in decreased expression of PPARD mRNA] CTD PMID:23834033 NCBI chr 6:35,342,558...35,428,178
Ensembl chr 6:35,342,558...35,428,191 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha multiple interactions EXP Nicotinamide Mononucleotide inhibits the reaction [[NNT protein inhibits the reaction [NNT protein modified form results in decreased susceptibility to Cisplatin]] which results in decreased expression of PPARGC1A mRNA] CTD PMID:36336710 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G PYCARD PYD and CARD domain containing multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of PYCARD protein] CTD PMID:30292833 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450 		JBrowse link
G RETN resistin multiple interactions ISO [resveratrol co-treated with Nicotinamide Mononucleotide] inhibits the reaction [RETN protein results in increased activity of GLB1 protein] CTD PMID:23827175 NCBI chr19:7,669,049...7,670,455
Ensembl chr19:7,669,049...7,670,455 		JBrowse link
G SHANK2 SH3 and multiple ankyrin repeat domains 2 multiple interactions EXP Nicotinamide Mononucleotide inhibits the reaction [[NNT protein inhibits the reaction [NNT protein modified form results in decreased susceptibility to Cisplatin]] which results in decreased expression of SHANK2 mRNA] CTD PMID:36336710 NCBI chr11:70,467,854...71,253,228
Ensembl chr11:70,467,854...71,252,577 		JBrowse link
G SIRT1 sirtuin 1 increases expression
multiple interactions		 ISO Nicotinamide Mononucleotide results in increased expression of SIRT1 mRNA
Nicotinamide Mononucleotide inhibits the reaction [Ethanol results in decreased expression of SIRT1 mRNA]; Nicotinamide Mononucleotide inhibits the reaction [Ethanol results in decreased expression of SIRT1 protein]		 CTD PMID:32087266 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G SLC47A1 solute carrier family 47 member 1 multiple interactions EXP Nicotinamide Mononucleotide inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr17:19,533,854...19,579,034
Ensembl chr17:19,495,385...19,579,034 		JBrowse link
G SLC47A2 solute carrier family 47 member 2 multiple interactions EXP Nicotinamide Mononucleotide inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr17:19,678,317...19,718,979
Ensembl chr17:19,678,288...19,718,979 		JBrowse link
G SQSTM1 sequestosome 1 multiple interactions EXP 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Nicotinamide Mononucleotide inhibits the reaction [[NNT protein inhibits the reaction [NNT protein modified form results in decreased susceptibility to Cisplatin]] which results in increased expression of SQSTM1 protein]]; Nicotinamide Mononucleotide inhibits the reaction [[NNT protein inhibits the reaction [NNT protein modified form results in decreased susceptibility to Cisplatin]] which results in increased expression of SQSTM1 protein] CTD PMID:36336710 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G TXNIP thioredoxin interacting protein multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of TXNIP mRNA]; Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of TXNIP protein] CTD PMID:30292833 NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579 		JBrowse link
G UCP2 uncoupling protein 2 multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Ethanol results in increased expression of UCP2 protein] CTD PMID:32087266 NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,672...73,982,843 		JBrowse link
oleoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSTA1 glutathione S-transferase alpha 1 multiple interactions EXP oleoyl-coenzyme A binds to and results in decreased activity of GSTA1 protein CTD PMID:10542059 NCBI chr 6:52,791,371...52,803,816
Ensembl chr 6:52,791,371...52,803,860 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions EXP oleoyl-coenzyme A binds to and results in increased activity of PPARA protein CTD PMID:11139385 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions EXP oleoyl-coenzyme A binds to and results in increased activity of PPARG protein CTD PMID:11139385 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
P(1),P(4)-bis(5'-guanosyl) tetraphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT10 nudix hydrolase 10 increases metabolic processing EXP NUDT10 protein results in increased metabolism of diguanosine tetraphosphate CTD PMID:12121577 NCBI chr  X:51,332,231...51,337,525
Ensembl chr  X:51,332,231...51,337,525 		JBrowse link
palmitoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOX1 acyl-CoA oxidase 1 increases metabolic processing
multiple interactions		 ISO ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A
[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide; benz(a)anthracene promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]; Dehydroepiandrosterone promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]; Tetrachlorodibenzodioxin promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]		 CTD PMID:10497882 NCBI chr17:75,941,507...75,979,166
Ensembl chr17:75,941,507...75,979,177 		JBrowse link
G CES1 carboxylesterase 1 increases hydrolysis ISO CES1 protein results in increased hydrolysis of Palmitoyl Coenzyme A CTD PMID:8611161 NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A multiple interactions ISO valproyl-coenzyme A inhibits the reaction [CPT1A protein results in increased metabolism of Palmitoyl Coenzyme A] CTD PMID:19854160 NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410 		JBrowse link
G DGAT1 diacylglycerol O-acyltransferase 1 multiple interactions EXP DGAT1 protein results in increased metabolism of [Palmitoyl Coenzyme A co-treated with Vitamin A] CTD PMID:16214399 NCBI chr 8:144,314,584...144,326,852
Ensembl chr 8:144,314,584...144,326,910 		JBrowse link
G GSTA1 glutathione S-transferase alpha 1 multiple interactions EXP Palmitoyl Coenzyme A binds to and results in decreased activity of GSTA1 protein CTD PMID:10542059 NCBI chr 6:52,791,371...52,803,816
Ensembl chr 6:52,791,371...52,803,860 		JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha decreases expression EXP Palmitoyl Coenzyme A results in decreased expression of HNF4A mRNA; Palmitoyl Coenzyme A results in decreased expression of HNF4A protein CTD PMID:17992261 NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,699...44,432,845 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions EXP
ISO		 Palmitoyl Coenzyme A binds to and results in increased activity of PPARA protein
Acetylglucosamine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Atorvastatin promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Atropine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Budesonide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Enalapril inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Fenofibrate promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; gamma-Aminobutyric Acid inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; gedunin inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]; Pravastatin promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Pyrazinamide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Saccharin inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; salicylamide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Tolazoline inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Tolmetin inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]		 CTD PMID:11139385 PMID:18812576 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions EXP Palmitoyl Coenzyme A binds to and results in increased activity of PPARG protein CTD PMID:11139385 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G SHBG sex hormone binding globulin decreases expression EXP Palmitoyl Coenzyme A results in decreased expression of SHBG mRNA; Palmitoyl Coenzyme A results in decreased expression of SHBG protein CTD PMID:17992261 NCBI chr17:7,614,064...7,633,372
Ensembl chr17:7,613,946...7,633,382 		JBrowse link
poly(cytidylic acid) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 multiple interactions
increases expression		 ISO Minocycline inhibits the reaction [Poly C results in increased expression of GRIA1 mRNA] CTD PMID:19660546 NCBI chr 5:153,489,615...153,813,869
Ensembl chr 5:153,489,615...153,813,869 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A increases expression
multiple interactions		 ISO Poly C results in increased expression of GRIN2A mRNA
Minocycline inhibits the reaction [Poly C results in increased expression of GRIN2A mRNA]		 CTD PMID:19660546 NCBI chr16:9,753,404...10,182,908
Ensembl chr16:9,753,404...10,182,928 		JBrowse link
G GRIN2C glutamate ionotropic receptor NMDA type subunit 2C multiple interactions
increases expression		 ISO Minocycline inhibits the reaction [Poly C results in increased expression of GRIN2C mRNA] CTD PMID:19660546 NCBI chr17:74,842,023...74,861,532
Ensembl chr17:74,842,023...74,861,504 		JBrowse link
G IL1B interleukin 1 beta increases expression ISO Poly C results in increased expression of IL1B protein CTD PMID:19660546 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
poly(guanylic acid) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTA2 actin alpha 2, smooth muscle multiple interactions ISO Poly G inhibits the reaction [Particulate Matter results in increased expression of ACTA2 mRNA]; Poly G inhibits the reaction [Particulate Matter results in increased expression of ACTA2 protein]; Poly G inhibits the reaction [Silicon Dioxide results in increased expression of ACTA2 mRNA]; Poly G inhibits the reaction [Silicon Dioxide results in increased expression of ACTA2 protein] CTD PMID:30391304 PMID:31028789 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,935,074...88,991,339 		JBrowse link
G ATF6 activating transcription factor 6 multiple interactions ISO Poly G inhibits the reaction [Silicon Dioxide results in increased expression of ATF6 protein] CTD PMID:31028789 NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574 		JBrowse link
G CASP12 caspase 12 (gene/pseudogene) multiple interactions ISO Poly G inhibits the reaction [Silicon Dioxide results in increased expression of CASP12 protein] CTD PMID:31028789 NCBI chr11:104,883,286...104,898,460
Ensembl chr11:104,885,718...104,898,670 		JBrowse link
G CDH1 cadherin 1 multiple interactions ISO Poly G inhibits the reaction [Particulate Matter results in decreased expression of CDH1 mRNA]; Poly G inhibits the reaction [Particulate Matter results in decreased expression of CDH1 protein]; Poly G inhibits the reaction [Silicon Dioxide results in decreased expression of CDH1 mRNA]; Poly G inhibits the reaction [Silicon Dioxide results in decreased expression of CDH1 protein] CTD PMID:30391304 PMID:31028789 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions ISO Poly G inhibits the reaction [Particulate Matter results in increased expression of COL1A1 mRNA]; Poly G inhibits the reaction [Silicon Dioxide results in increased expression of COL1A1 mRNA] CTD PMID:30391304 PMID:31028789 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632 		JBrowse link
G COL3A1 collagen type III alpha 1 chain multiple interactions ISO Poly G inhibits the reaction [Particulate Matter results in increased expression of COL3A1 mRNA]; Poly G inhibits the reaction [Silicon Dioxide results in increased expression of COL3A1 mRNA] CTD PMID:30391304 PMID:31028789 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 multiple interactions ISO Poly G inhibits the reaction [Silicon Dioxide results in increased expression of DDIT3 protein] CTD PMID:31028789 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO Poly G inhibits the reaction [Silicon Dioxide results in increased expression of ERN1 protein] CTD PMID:31028789 NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO Poly G inhibits the reaction [Silicon Dioxide results in increased expression of HSPA5 protein] CTD PMID:31028789 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G MARCO macrophage receptor with collagenous structure multiple interactions ISO Poly G inhibits the reaction [MARCO protein binds to and results in increased uptake of Polystyrenes]
Poly G inhibits the reaction [Particulate Matter results in increased expression of MARCO protein]; Poly G inhibits the reaction [Silicon Dioxide results in increased expression of MARCO protein]		 CTD PMID:17361018 PMID:30391304 PMID:31028789 NCBI chr 2:118,942,194...118,994,660
Ensembl chr 2:118,942,194...118,994,660 		JBrowse link
G VIM vimentin multiple interactions ISO Poly G inhibits the reaction [Particulate Matter results in increased expression of VIM mRNA]; Poly G inhibits the reaction [Particulate Matter results in increased expression of VIM protein]; Poly G inhibits the reaction [Silicon Dioxide results in increased expression of VIM mRNA]; Poly G inhibits the reaction [Silicon Dioxide results in increased expression of VIM protein] CTD PMID:30391304 PMID:31028789 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
poly(I:C) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABHD2 abhydrolase domain containing 2, acylglycerol lipase multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ABHD2 mRNA CTD PMID:26923065 NCBI chr15:89,040,998...89,202,355
Ensembl chr15:89,087,459...89,202,355 		JBrowse link
G ABLIM1 actin binding LIM protein 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ABLIM1 mRNA CTD PMID:26923065 NCBI chr10:114,431,110...114,801,373
Ensembl chr10:114,431,112...114,768,061 		JBrowse link
G ACADS acyl-CoA dehydrogenase short chain multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of ACADS mRNA CTD PMID:26923065 NCBI chr12:120,725,826...120,740,008
Ensembl chr12:120,725,774...120,740,008 		JBrowse link
G ADAM10 ADAM metallopeptidase domain 10 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ADAM10 mRNA CTD PMID:26923065 NCBI chr15:58,588,809...58,749,707
Ensembl chr15:58,588,809...58,749,791 		JBrowse link
G ADAR adenosine deaminase RNA specific affects localization EXP Poly I-C affects the localization of ADAR protein CTD PMID:22240577 NCBI chr 1:154,582,057...154,627,997
Ensembl chr 1:154,581,695...154,628,013 		JBrowse link
G AHCYL1 adenosylhomocysteinase like 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of AHCYL1 mRNA CTD PMID:26923065 NCBI chr 1:109,984,765...110,023,742
Ensembl chr 1:109,984,765...110,023,742 		JBrowse link
G AHR aryl hydrocarbon receptor increases expression EXP Poly I-C results in increased expression of AHR mRNA; Poly I-C results in increased expression of AHR protein CTD PMID:27783115 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G AKAP5 A-kinase anchoring protein 5 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of AKAP5 mRNA CTD PMID:26923065 NCBI chr14:64,465,499...64,474,503
Ensembl chr14:64,465,499...64,474,503 		JBrowse link
G APP amyloid beta precursor protein multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of APP mRNA CTD PMID:26923065 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 multiple interactions
increases degradation		 ISO APPL1 protein inhibits the reaction [Poly I-C results in increased expression of IL1B protein]; APPL1 protein inhibits the reaction [Poly I-C results in increased expression of TNF protein]; APPL1 protein promotes the reaction [Poly I-C results in increased expression of CCL5 mRNA]; APPL1 protein promotes the reaction [Poly I-C results in increased expression of CXCL10 mRNA]; APPL1 protein promotes the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; APPL1 protein promotes the reaction [Poly I-C results in increased phosphorylation of IKBKE protein]; APPL1 protein promotes the reaction [Poly I-C results in increased phosphorylation of IRF3 protein]; APPL1 protein promotes the reaction [Poly I-C results in increased phosphorylation of TBK1 protein]; bafilomycin A1 promotes the reaction [Poly I-C results in increased degradation of APPL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Poly I-C results in increased degradation of APPL1 protein]; Chloroquine inhibits the reaction [Poly I-C results in increased degradation of APPL1 protein]; trametinib inhibits the reaction [Poly I-C results in increased degradation of APPL1 protein]; U 0126 inhibits the reaction [Poly I-C results in increased degradation of APPL1 protein] CTD PMID:25780039 NCBI chr 3:57,227,729...57,273,471
Ensembl chr 3:57,227,726...57,278,105 		JBrowse link
G ARC activity regulated cytoskeleton associated protein affects methylation ISO Poly I-C affects the methylation of ARC promoter CTD PMID:32843831 NCBI chr 8:142,611,049...142,614,479
Ensembl chr 8:142,611,049...142,614,479 		JBrowse link
G ARFGEF3 ARFGEF family member 3 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ARFGEF3 mRNA CTD PMID:26923065 NCBI chr 6:138,161,939...138,344,663
Ensembl chr 6:138,161,939...138,344,663 		JBrowse link
G ARG2 arginase 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of ARG2 mRNA CTD PMID:26923065 NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708 		JBrowse link
G ARHGAP11A Rho GTPase activating protein 11A multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of ARHGAP11A mRNA CTD PMID:26923065 NCBI chr15:32,615,144...32,639,941
Ensembl chr15:32,615,144...32,639,941 		JBrowse link
G ARHGAP44 Rho GTPase activating protein 44 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ARHGAP44 mRNA CTD PMID:26923065 NCBI chr17:12,789,498...12,991,643
Ensembl chr17:12,789,498...12,991,643 		JBrowse link
G ARHGAP9 Rho GTPase activating protein 9 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of ARHGAP9 mRNA CTD PMID:26923065 NCBI chr12:57,472,269...57,488,824
Ensembl chr12:57,472,264...57,488,814 		JBrowse link
G ARHGEF12 Rho guanine nucleotide exchange factor 12 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ARHGEF12 mRNA CTD PMID:26923065 NCBI chr11:120,336,413...120,489,937
Ensembl chr11:120,336,413...120,489,937 		JBrowse link
G ARHGEF7 Rho guanine nucleotide exchange factor 7 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ARHGEF7 mRNA CTD PMID:26923065 NCBI chr13:111,114,619...111,305,734
Ensembl chr13:111,114,559...111,305,737 		JBrowse link
G ARSB arylsulfatase B multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ARSB mRNA CTD PMID:26923065 NCBI chr 5:78,777,209...78,985,958
Ensembl chr 5:78,777,209...78,986,087 		JBrowse link
G ART3 ADP-ribosyltransferase 3 (inactive) multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of ART3 mRNA CTD PMID:26923065 NCBI chr 4:76,011,190...76,112,786
Ensembl chr 4:76,011,184...76,114,048 		JBrowse link
G ATF3 activating transcription factor 3 increases expression EXP Poly I-C results in increased expression of ATF3 mRNA CTD PMID:27783115 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777 		JBrowse link
G ATP2B2 ATPase plasma membrane Ca2+ transporting 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ATP2B2 mRNA CTD PMID:26923065 NCBI chr 3:10,324,023...10,708,007
Ensembl chr 3:10,324,023...10,708,007 		JBrowse link
G ATXN3 ataxin 3 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ATXN3 mRNA CTD PMID:26923065 NCBI chr14:92,044,775...92,106,582
Ensembl chr14:92,044,496...92,106,621 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression EXP Poly I-C results in increased expression of BAX protein CTD PMID:21418039 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression EXP Poly I-C results in decreased expression of BCL2 protein CTD PMID:21418039 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2A1 BCL2 related protein A1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of BCL2A1 mRNA CTD PMID:26923065 NCBI chr15:79,960,892...79,971,196
Ensembl chr15:79,960,892...79,971,196 		JBrowse link
G BDNF brain derived neurotrophic factor multiple interactions
affects methylation		 ISO [Poly I-C results in increased susceptibility to 4-iodo-2,5-dimethoxyphenylisopropylamine] which results in increased expression of BDNF mRNA; Poly I-C promotes the reaction [4-iodo-2,5-dimethoxyphenylisopropylamine results in increased expression of BDNF mRNA]
Poly I-C affects the methylation of BDNF promoter		 CTD PMID:24889602 PMID:32843831 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G BID BH3 interacting domain death agonist decreases expression EXP Poly I-C results in decreased expression of BID protein CTD PMID:21418039 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 multiple interactions EXP Poly I-C promotes the reaction [arsenic trioxide results in decreased expression of BIRC5 protein] CTD PMID:21418039 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636 		JBrowse link
G BIRC6 baculoviral IAP repeat containing 6 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of BIRC6 mRNA CTD PMID:26923065 NCBI chr 2:32,357,023...32,618,878
Ensembl chr 2:32,357,023...32,619,571 		JBrowse link
G BLMH bleomycin hydrolase multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of BLMH mRNA CTD PMID:26923065 NCBI chr17:30,248,203...30,291,944
Ensembl chr17:30,248,203...30,292,056 		JBrowse link
G BLTP1 bridge-like lipid transfer protein family member 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of BLTP1 mRNA CTD PMID:26923065 NCBI chr 4:122,152,331...122,362,752
Ensembl chr 4:122,152,331...122,364,167 		JBrowse link
G BRMS1L BRMS1 like transcriptional repressor multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of BRMS1L mRNA CTD PMID:26923065 NCBI chr14:35,826,338...35,871,963
Ensembl chr14:35,826,338...35,932,325 		JBrowse link
G BROX BRO1 domain and CAAX motif containing multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of BROX mRNA CTD PMID:26923065 NCBI chr 1:222,712,564...222,735,187
Ensembl chr 1:222,712,553...222,735,196 		JBrowse link
G C16orf90 chromosome 16 open reading frame 90 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of C10H16ORF90 mRNA CTD PMID:26923065 NCBI chr16:3,493,484...3,496,652
Ensembl chr16:3,493,484...3,495,489 		JBrowse link
G C1QTNF7 C1q and TNF related 7 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of C1QTNF7 mRNA CTD PMID:26923065 NCBI chr 4:15,339,786...15,446,167
Ensembl chr 4:15,339,818...15,446,167 		JBrowse link
G CA3 carbonic anhydrase 3 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of CA3 mRNA CTD PMID:26923065 NCBI chr 8:85,438,859...85,449,040
Ensembl chr 8:85,373,436...85,449,040 		JBrowse link
G CAGE1 cancer antigen 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of CAGE1 mRNA CTD PMID:26923065 NCBI chr 6:7,326,659...7,389,742
Ensembl chr 6:7,326,656...7,389,742 		JBrowse link
G CASP3 caspase 3 multiple interactions
increases activity		 EXP Acetylcysteine inhibits the reaction [arsenic trioxide promotes the reaction [Poly I-C results in increased activity of CASP3 protein]]; Acetylcysteine inhibits the reaction [Poly I-C promotes the reaction [arsenic trioxide results in increased activity of CASP3 protein]]; arsenic trioxide promotes the reaction [Poly I-C results in increased activity of CASP3 protein]; Poly I-C promotes the reaction [arsenic trioxide results in increased activity of CASP3 protein] CTD PMID:21418039 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP8 caspase 8 multiple interactions
increases activity		 EXP arsenic trioxide promotes the reaction [Poly I-C results in increased activity of CASP8 protein]; Poly I-C promotes the reaction [arsenic trioxide results in increased activity of CASP8 protein] CTD PMID:21418039 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CASP9 caspase 9 multiple interactions
increases activity		 EXP Acetylcysteine inhibits the reaction [arsenic trioxide promotes the reaction [Poly I-C results in increased activity of CASP9 protein]]; Acetylcysteine inhibits the reaction [Poly I-C promotes the reaction [arsenic trioxide results in increased activity of CASP9 protein]]; arsenic trioxide promotes the reaction [Poly I-C results in increased activity of CASP9 protein]; Poly I-C promotes the reaction [arsenic trioxide results in increased activity of CASP9 protein] CTD PMID:21418039 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAT catalase decreases expression ISO Poly I-C results in decreased expression of CAT mRNA CTD PMID:23939143 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CAV1 caveolin 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of CAV1 mRNA CTD PMID:26923065 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179 		JBrowse link
G CBX1 chromobox 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of CBX1 mRNA CTD PMID:26923065 NCBI chr17:48,070,059...48,101,478
Ensembl chr17:48,070,052...48,101,478 		JBrowse link
G CBX6 chromobox 6 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of CBX6 mRNA CTD PMID:26923065 NCBI chr22:38,861,422...38,872,216
Ensembl chr22:38,861,422...38,872,249 		JBrowse link
G CCL1 C-C motif chemokine ligand 1 increases expression EXP Poly I-C results in increased expression of CCL1 mRNA CTD PMID:27783115 NCBI chr17:34,360,328...34,363,233
Ensembl chr17:34,360,328...34,363,233 		JBrowse link
G CCL11 C-C motif chemokine ligand 11 multiple interactions
increases secretion		 ISO methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL11 protein] CTD PMID:24056979 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions
increases secretion
increases expression		 ISO
EXP		 methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL2 protein]
Poly I-C results in increased expression of CCL2 mRNA		 CTD PMID:23939143 PMID:24056979 PMID:34740670 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 multiple interactions
increases expression		 ISO Ethanol inhibits the reaction [Poly I-C results in increased expression of CCL3 protein] CTD PMID:19500611 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G CCL4 C-C motif chemokine ligand 4 multiple interactions
increases expression
increases secretion		 ISO
EXP		 Ethanol inhibits the reaction [Poly I-C results in increased expression of CCL4 protein]; methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL4 protein]
6-formylindolo(3,2-b)carbazole inhibits the reaction [Poly I-C results in increased expression of CCL4 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [Poly I-C results in increased expression of CCL4 mRNA]		 CTD PMID:19500611 PMID:24056979 PMID:27783115 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 multiple interactions
increases expression
increases secretion		 ISO
EXP		 APPL1 protein promotes the reaction [Poly I-C results in increased expression of CCL5 mRNA]; methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL5 protein]; trametinib promotes the reaction [Poly I-C results in increased expression of CCL5 mRNA]
Poly I-C results in increased expression of CCL5; Poly I-C results in increased expression of CCL5 mRNA
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; [Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; helenalin inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; IL4 protein promotes the reaction [Poly I-C results in increased expression of CCL5 mRNA]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; Particulate Matter inhibits the reaction [Poly I-C results in increased expression of CCL5]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; Vehicle Emissions inhibits the reaction [Poly I-C results in increased expression of CCL5]		 CTD PMID:23688403 PMID:24056979 PMID:24709138 PMID:25780039 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CD40 CD40 molecule increases expression
multiple interactions		 EXP Poly I-C results in increased expression of CD40 protein
[Poly I-C co-treated with IFNG protein] results in increased secretion of CD40 protein		 CTD PMID:15246609 PMID:16224278 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CD80 CD80 molecule increases expression EXP Poly I-C results in increased expression of CD80 protein CTD PMID:15246609 NCBI chr 3:119,524,293...119,559,614
Ensembl chr 3:119,524,293...119,559,614 		JBrowse link
G CD83 CD83 molecule increases expression
multiple interactions		 EXP Poly I-C results in increased expression of CD83 protein
CEP-11004 inhibits the reaction [Poly I-C results in increased expression of CD83 protein]; SB 203580 inhibits the reaction [Poly I-C results in increased expression of CD83 protein]		 CTD PMID:17698565 NCBI chr 6:14,117,256...14,136,918
Ensembl chr 6:14,117,256...14,136,918 		JBrowse link
G CD86 CD86 molecule multiple interactions
increases expression		 EXP [Poly I-C co-treated with IFNG protein] results in increased secretion of CD86 protein; CEP-11004 inhibits the reaction [Poly I-C results in increased expression of CD86 protein]; Particulate Matter analog inhibits the reaction [Poly I-C results in increased expression of CD86 protein]; SB 203580 inhibits the reaction [Poly I-C results in increased expression of CD86 protein]; Vehicle Emissions analog inhibits the reaction [Poly I-C results in increased expression of CD86 protein] CTD PMID:15246609 PMID:16224278 PMID:16890772 PMID:17698565 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G CDC42 cell division cycle 42 multiple interactions EXP [Poly I-C co-treated with Atorvastatin] results in decreased expression of CDC42 mRNA CTD PMID:34696514 NCBI chr 1:22,052,709...22,101,360
Ensembl chr 1:22,052,627...22,101,360 		JBrowse link
G CDX2 caudal type homeobox 2 multiple interactions EXP [Poly I-C co-treated with 6-formylindolo(3,2-b)carbazole] results in increased expression of CDX2 mRNA; [Poly I-C co-treated with Tetrachlorodibenzodioxin] results in increased expression of CDX2 mRNA CTD PMID:27783115 NCBI chr13:27,960,918...27,969,315
Ensembl chr13:27,960,918...27,969,315 		JBrowse link
G CELF1 CUGBP Elav-like family member 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of CELF1 mRNA CTD PMID:26923065 NCBI chr11:47,465,937...47,565,539
Ensembl chr11:47,465,933...47,565,569 		JBrowse link
G CFAP263 cilia and flagella associated protein 263 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of CCDC113 mRNA CTD PMID:26923065 NCBI chr16:58,249,936...58,283,836
Ensembl chr16:58,231,157...58,283,836 		JBrowse link
G CFP complement factor properdin multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of CFP mRNA CTD PMID:26923065 NCBI chr  X:47,623,282...47,630,305
Ensembl chr  X:47,623,172...47,630,305 		JBrowse link
G CHSY1 chondroitin sulfate synthase 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of CHSY1 mRNA CTD PMID:26923065 NCBI chr15:101,175,727...101,252,048
Ensembl chr15:101,175,727...101,252,048 		JBrowse link
G CIBAR2 CBY1 interacting BAR domain containing 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of CIBAR2 mRNA CTD PMID:26923065 NCBI chr16:85,098,358...85,112,472
Ensembl chr16:85,098,358...85,112,472 		JBrowse link
G CLCC1 chloride channel CLIC like 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of CLCC1 mRNA CTD PMID:26923065 NCBI chr 1:108,929,505...108,963,484
Ensembl chr 1:108,881,885...108,963,527 		JBrowse link
G CLEC14A C-type lectin domain containing 14A multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of CLEC14A mRNA CTD PMID:26923065 NCBI chr14:38,254,000...38,256,093
Ensembl chr14:38,254,000...38,256,093 		JBrowse link
G CLIP3 CAP-Gly domain containing linker protein 3 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of CLIP3 mRNA CTD PMID:26923065 NCBI chr19:36,014,660...36,032,873
Ensembl chr19:36,014,660...36,033,343 		JBrowse link
G CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of CNNM1 mRNA CTD PMID:26923065 NCBI chr10:99,329,356...99,394,330
Ensembl chr10:99,329,356...99,394,330 		JBrowse link
G CNR1 cannabinoid receptor 1 multiple interactions ISO Cannabidiol inhibits the reaction [Poly I-C inhibits the reaction [Rimonabant binds to CNR1 protein]]; Poly I-C inhibits the reaction [Rimonabant binds to CNR1 protein] CTD PMID:31202911 NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347 		JBrowse link
G CNR2 cannabinoid receptor 2 increases expression ISO Poly I-C results in increased expression of CNR2 mRNA CTD PMID:27317300 NCBI chr 1:23,870,515...23,913,362
Ensembl chr 1:23,870,515...23,913,362 		JBrowse link
G CNTN1 contactin 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of CNTN1 mRNA CTD PMID:26923065 NCBI chr12:40,692,439...41,072,415
Ensembl chr12:40,692,439...41,072,415 		JBrowse link
G CRABP1 cellular retinoic acid binding protein 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of CRABP1 mRNA CTD PMID:26923065 NCBI chr15:78,340,353...78,348,225
Ensembl chr15:78,340,353...78,348,225 		JBrowse link
G CSF2 colony stimulating factor 2 multiple interactions
increases secretion
increases expression		 ISO
EXP		 Ethanol inhibits the reaction [Poly I-C results in increased expression of CSF2 protein]
Smoke inhibits the reaction [Poly I-C results in increased secretion of CSF2 protein]		 CTD PMID:19500611 PMID:35817128 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G CTTNBP2 cortactin binding protein 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of CTTNBP2 mRNA CTD PMID:26923065 NCBI chr 7:117,710,651...117,873,441
Ensembl chr 7:117,710,651...117,874,139 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 increases expression
multiple interactions		 ISO Poly I-C results in increased expression of CXCL1 mRNA
Poly I-C results in increased expression of CXCL1 protein
Ethanol inhibits the reaction [Poly I-C results in increased expression of CXCL1 protein]		 CTD PMID:19500611 PMID:23939143 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 multiple interactions
increases secretion
increases expression		 ISO
EXP		 APPL1 protein promotes the reaction [Poly I-C results in increased expression of CXCL10 mRNA]; chrysin inhibits the reaction [Poly I-C results in increased expression of CXCL10 mRNA]; eriodictyol inhibits the reaction [Poly I-C results in increased expression of CXCL10 mRNA]; Luteolin inhibits the reaction [Poly I-C results in increased expression of CXCL10 mRNA]; Quercetin inhibits the reaction [Poly I-C results in increased expression of CXCL10 mRNA]; trametinib promotes the reaction [Poly I-C results in increased expression of CXCL10 mRNA]
Poly I-C results in increased secretion of CXCL10 protein
cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester inhibits the reaction [Poly I-C results in increased expression of CXCL10 mRNA]
[Dronabinol co-treated with Cannabidiol] inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein]; [Pam(3)CSK(4) peptide co-treated with Antigens, Bacterial co-treated with Poly I-C co-treated with Lipopolysaccharides co-treated with FSL-1 lipoprotein, synthetic co-treated with Imiquimod co-treated with Polyribonucleotides co-treated with ProMune] results in increased expression of CXCL10 protein; bafilomycin A1 inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein]; Cannabidiol inhibits the reaction [Poly I-C results in increased expression of CXCL10 mRNA]; Cannabidiol inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein]; Cannabidiol inhibits the reaction [Poly I-C results in increased secretion of CXCL10 protein]; Chloroquine inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein]; Dronabinol inhibits the reaction [Poly I-C results in increased expression of CXCL10 mRNA]; Dronabinol inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein]; Particulate Matter inhibits the reaction [[Pam(3)CSK(4) peptide co-treated with Antigens, Bacterial co-treated with Poly I-C co-treated with Lipopolysaccharides co-treated with FSL-1 lipoprotein, synthetic co-treated with Imiquimod co-treated with Polyribonucleotides co-treated with ProMune] results in increased expression of CXCL10 protein]; Phosphorothioate Oligonucleotides inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein]; Smoke inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein]; Smoke inhibits the reaction [Poly I-C results in increased secretion of CXCL10 protein]; Vehicle Emissions inhibits the reaction [[Pam(3)CSK(4) peptide co-treated with Antigens, Bacterial co-treated with Poly I-C co-treated with Lipopolysaccharides co-treated with FSL-1 lipoprotein, synthetic co-treated with Imiquimod co-treated with Polyribonucleotides co-treated with ProMune] results in increased expression of CXCL10 protein]
Poly I-C results in increased expression of CXCL10 mRNA; Poly I-C results in increased expression of CXCL10 protein		 CTD PMID:19426678 PMID:25780039 PMID:26682054 PMID:28003376 PMID:28572013 More... NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 increases expression ISO Poly I-C results in increased expression of CXCL2 mRNA CTD PMID:23939143 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions
increases expression
increases secretion		 EXP 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [Estradiol promotes the reaction [Poly I-C results in increased expression of CXCL8 protein]]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane promotes the reaction [Poly I-C results in increased expression of CXCL8 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Poly I-C results in increased secretion of CXCL8 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Poly I-C results in increased secretion of CXCL8 protein]; 4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol promotes the reaction [Poly I-C results in increased expression of CXCL8 protein]; [Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; CpG ODN 2006 inhibits the reaction [Poly I-C results in increased secretion of CXCL8 protein]; Estradiol promotes the reaction [Poly I-C results in increased expression of CXCL8 protein]; helenalin inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; IL4 protein promotes the reaction [Poly I-C results in increased expression of CXCL8 mRNA]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; N-(3,5-bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide inhibits the reaction [Poly I-C results in increased secretion of CXCL8 protein]; Particulate Matter promotes the reaction [Poly I-C results in increased expression of CXCL8]; Poly I-C affects the reaction [Gold Sodium Thiosulfate results in increased secretion of CXCL8 protein]; pyrazolanthrone inhibits the reaction [Poly I-C results in increased secretion of CXCL8 protein]; RTKI cpd inhibits the reaction [Poly I-C results in increased secretion of CXCL8 protein]; SB 203580 inhibits the reaction [Poly I-C results in increased secretion of CXCL8 protein]; Smoke inhibits the reaction [Poly I-C results in increased secretion of CXCL8 protein]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; TLR3 protein affects the reaction [Poly I-C results in increased expression of CXCL8 mRNA]; TP53 protein affects the reaction [Poly I-C results in increased expression of CXCL8 mRNA]; Vehicle Emissions promotes the reaction [Poly I-C results in increased expression of CXCL8]; Vehicle Emissions promotes the reaction [Poly I-C results in increased secretion of CXCL8 protein]
Poly I-C results in increased expression of CXCL8; Poly I-C results in increased expression of CXCL8 mRNA; Poly I-C results in increased expression of CXCL8 protein		 CTD PMID:17669408 PMID:18779317 PMID:20932985 PMID:23618096 PMID:23688403 More... NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 multiple interactions
increases secretion
increases expression		 ISO Luteolin inhibits the reaction [Poly I-C results in increased expression of CXCL9 mRNA]; methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CXCL9 protein] CTD PMID:19426678 PMID:24056979 NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509 		JBrowse link
G CYFIP2 cytoplasmic FMR1 interacting protein 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of CYFIP2 mRNA CTD PMID:26923065 NCBI chr 5:157,266,123...157,395,594
Ensembl chr 5:157,266,079...157,395,595 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions EXP Poly I-C promotes the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1A1 mRNA] CTD PMID:27783115 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP2C18 cytochrome P450 family 2 subfamily C member 18 decreases expression ISO Poly I-C results in decreased expression of CYP2C11 mRNA CTD PMID:23939143 NCBI chr10:94,683,729...94,736,190
Ensembl chr10:94,683,729...94,736,190 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 decreases expression ISO Poly I-C results in decreased expression of CYP2C6V1 mRNA CTD PMID:23939143 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547 		JBrowse link
G CYRIA CYFIP related Rac1 interactor A multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of CYRIA mRNA CTD PMID:26923065 NCBI chr 2:16,549,459...16,665,834
Ensembl chr 2:16,549,459...16,666,331 		JBrowse link
G CYSRT1 cysteine rich tail 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of CYSRT1 mRNA CTD PMID:26923065 NCBI chr 9:137,225,174...137,226,315
Ensembl chr 9:137,225,174...137,226,315 		JBrowse link
G DAB1 DAB adaptor protein 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of DAB1 mRNA CTD PMID:26923065 NCBI chr 1:56,994,778...58,546,726
Ensembl chr 1:56,994,778...58,546,734 		JBrowse link
G DCK deoxycytidine kinase multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of DCK mRNA CTD PMID:26923065 NCBI chr 4:70,993,649...71,030,914
Ensembl chr 4:70,992,538...71,030,914 		JBrowse link
G DCUN1D3 defective in cullin neddylation 1 domain containing 3 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of DCUN1D3 mRNA CTD PMID:26923065 NCBI chr16:20,854,925...20,900,358
Ensembl chr16:20,854,925...20,900,358 		JBrowse link
G DCUN1D4 defective in cullin neddylation 1 domain containing 4 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of DCUN1D4 mRNA CTD PMID:26923065 NCBI chr 4:51,833,884...51,916,837
Ensembl chr 4:51,843,000...51,916,837 		JBrowse link
G DDX3X DEAD-box helicase 3 X-linked multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of DDX3X mRNA CTD PMID:26923065 NCBI chr  X:41,333,308...41,364,472
Ensembl chr  X:41,333,348...41,364,472 		JBrowse link
G DEFB4A defensin beta 4A increases secretion EXP Poly I-C results in increased secretion of DEFB4 protein CTD PMID:17669408 NCBI chr 8:7,894,677...7,896,716
Ensembl chr 8:7,894,677...7,896,716
Ensembl chr 8:7,894,677...7,896,716 		JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of DLG1 mRNA CTD PMID:26923065 NCBI chr 3:197,042,560...197,299,321
Ensembl chr 3:197,042,560...197,299,330 		JBrowse link
G DNM2 dynamin 2 multiple interactions ISO DNM2 protein promotes the reaction [Poly I-C results in increased phosphorylation of IRF3 protein] CTD PMID:25780039 NCBI chr19:10,718,079...10,831,903
Ensembl chr19:10,718,055...10,833,488 		JBrowse link
G DNMT1 DNA methyltransferase 1 multiple interactions EXP [Arsenicals co-treated with Poly I-C co-treated with Alitretinoin] results in increased expression of DNMT1 mRNA; [Arsenicals co-treated with Poly I-C] results in increased expression of DNMT1 mRNA CTD PMID:34303791 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha multiple interactions EXP [Arsenicals co-treated with Poly I-C co-treated with Alitretinoin] results in increased expression of DNMT3A mRNA; [Arsenicals co-treated with Poly I-C] results in increased expression of DNMT3A mRNA CTD PMID:34303791 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590 		JBrowse link
G EEA1 early endosome antigen 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of EEA1 mRNA CTD PMID:26923065 NCBI chr12:92,770,637...92,929,295
Ensembl chr12:92,770,637...92,929,331 		JBrowse link
G EGR1 early growth response 1 multiple interactions
affects methylation		 ISO [Poly I-C results in increased susceptibility to 4-iodo-2,5-dimethoxyphenylisopropylamine] which results in increased expression of EGR1 mRNA; Poly I-C promotes the reaction [4-iodo-2,5-dimethoxyphenylisopropylamine results in increased expression of EGR1 mRNA]
Poly I-C affects the methylation of EGR1 promoter		 CTD PMID:24889602 PMID:32843831 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303 		JBrowse link
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 increases expression
increases phosphorylation
increases response to substance		 EXP
ISO		 Poly I-C results in increased expression of EIF2AK2 mRNA
Poly I-C results in increased phosphorylation of EIF2AK2 protein
EIF2AK2 results in increased susceptibility to Poly I-C		 CTD PMID:10944112 PMID:17669408 PMID:22240577 PMID:22558189 NCBI chr 2:37,099,210...37,156,980
Ensembl chr 2:37,099,210...37,157,522 		JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation EXP Poly I-C results in increased phosphorylation of EIF2S1 protein CTD PMID:22240577 NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,328...67,386,516 		JBrowse link
G F11R F11 receptor multiple interactions
decreases expression		 EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Poly I-C results in decreased expression of F11R protein]; CpG ODN 2006 inhibits the reaction [Poly I-C results in decreased expression of F11R protein]; N-(3,5-bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide inhibits the reaction [Poly I-C results in decreased expression of F11R protein]; RTKI cpd inhibits the reaction [Poly I-C results in decreased expression of F11R protein]; SB 203580 inhibits the reaction [Poly I-C results in decreased expression of F11R protein] CTD PMID:20932985 NCBI chr 1:160,995,211...161,021,152
Ensembl chr 1:160,995,211...161,021,175 		JBrowse link
G FABP4 fatty acid binding protein 4 increases expression ISO Poly I-C results in increased expression of FABP4 mRNA CTD PMID:15705927 NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236 		JBrowse link
G FAM107A family with sequence similarity 107 member A multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of FAM107A mRNA CTD PMID:26923065 NCBI chr 3:58,564,117...58,627,610
Ensembl chr 3:58,564,117...58,627,610 		JBrowse link
G FMR1 fragile X messenger ribonucleoprotein 1 multiple interactions
decreases expression		 ISO Suramin inhibits the reaction [Poly I-C results in decreased expression of FMR1 protein] CTD PMID:23516405 NCBI chr  X:147,911,919...147,951,125
Ensembl chr  X:147,911,919...147,951,125 		JBrowse link
G FXYD3 FXYD domain containing ion transport regulator 3 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of FXYD3 mRNA CTD PMID:26923065 NCBI chr19:35,115,823...35,124,324
Ensembl chr19:35,115,823...35,124,324 		JBrowse link
G FYTTD1 forty-two-three domain containing 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of FYTTD1 mRNA CTD PMID:26923065 NCBI chr 3:197,749,533...197,787,596
Ensembl chr 3:197,737,179...197,787,596 		JBrowse link
G G3BP1 G3BP stress granule assembly factor 1 affects localization EXP Poly I-C affects the localization of G3BP1 protein CTD PMID:22240577 NCBI chr 5:151,771,954...151,812,785
Ensembl chr 5:151,771,045...151,812,911 		JBrowse link
G G3BP2 G3BP stress granule assembly factor 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of G3BP2 mRNA CTD PMID:26923065 NCBI chr 4:75,642,786...75,724,437
Ensembl chr 4:75,641,849...75,724,589 		JBrowse link
G GABRA1 gamma-aminobutyric acid type A receptor subunit alpha1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of GABRA1 mRNA CTD PMID:26923065 NCBI chr 5:161,847,191...161,899,971
Ensembl chr 5:161,847,063...161,899,981 		JBrowse link
G GABRB2 gamma-aminobutyric acid type A receptor subunit beta2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of GABRB2 mRNA CTD PMID:26923065 NCBI chr 5:161,288,436...161,548,404
Ensembl chr 5:161,288,429...161,549,044 		JBrowse link
G GABRG2 gamma-aminobutyric acid type A receptor subunit gamma2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of GABRG2 mRNA CTD PMID:26923065 NCBI chr 5:162,067,465...162,155,539
Ensembl chr 5:162,000,057...162,162,977 		JBrowse link
G GAD1 glutamate decarboxylase 1 decreases expression
multiple interactions		 ISO Poly I-C results in decreased expression of GAD1 protein
Cannabidiol inhibits the reaction [Poly I-C results in decreased expression of GAD1 protein]		 CTD PMID:31202911 NCBI chr 2:170,813,210...170,861,151
Ensembl chr 2:170,813,213...170,861,151 		JBrowse link
G GDAP1 ganglioside induced differentiation associated protein 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of GDAP1 mRNA CTD PMID:26923065 NCBI chr 8:74,350,403...74,488,872
Ensembl chr 8:74,320,613...74,518,007 		JBrowse link
G GDI1 GDP dissociation inhibitor 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of GDI1 mRNA CTD PMID:26923065 NCBI chr  X:154,437,154...154,443,467
Ensembl chr  X:154,436,913...154,443,467 		JBrowse link
G GET3 guided entry of tail-anchored proteins factor 3, ATPase multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of GET3 mRNA CTD PMID:26923065 NCBI chr19:12,737,106...12,748,323
Ensembl chr19:12,737,139...12,748,323 		JBrowse link
G GFAP glial fibrillary acidic protein increases expression ISO Poly I-C results in increased expression of GFAP mRNA CTD PMID:27317300 NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937 		JBrowse link
G GH1 growth hormone 1 decreases expression ISO Poly I-C results in decreased expression of GH protein CTD PMID:21195166 NCBI chr17:63,917,203...63,918,839
Ensembl chr17:63,917,200...63,918,839 		JBrowse link
G GLCE glucuronic acid epimerase multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of GLCE mRNA CTD PMID:26923065 NCBI chr15:69,160,635...69,272,207
Ensembl chr15:69,160,584...69,272,217 		JBrowse link
G GLRB glycine receptor beta multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of GLRB mRNA CTD PMID:26923065 NCBI chr 4:157,076,150...157,172,090
Ensembl chr 4:157,076,125...157,172,090 		JBrowse link
G GLYR1 glyoxylate reductase 1 homolog multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of GLYR1 mRNA CTD PMID:26923065 NCBI chr16:4,803,203...4,847,288
Ensembl chr16:4,803,203...4,847,288 		JBrowse link
G GMFB glia maturation factor beta multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of GMFB mRNA CTD PMID:26923065 NCBI chr14:54,474,485...54,488,980
Ensembl chr14:54,474,484...54,489,025 		JBrowse link
G GMPPB GDP-mannose pyrophosphorylase B multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of GMPPB mRNA CTD PMID:26923065 NCBI chr 3:49,719,916...49,723,951
Ensembl chr 3:49,716,844...49,723,973 		JBrowse link
G GPATCH2L G-patch domain containing 2 like multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of GPATCH2L mRNA CTD PMID:26923065 NCBI chr14:76,151,922...76,235,555
Ensembl chr14:76,151,916...76,254,342 		JBrowse link
G GPBP1 GC-rich promoter binding protein 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of GPBP1 mRNA CTD PMID:26923065 NCBI chr 5:57,174,059...57,264,679
Ensembl chr 5:57,173,948...57,264,679 		JBrowse link
G GSR glutathione-disulfide reductase decreases expression ISO Poly I-C results in decreased expression of GSR mRNA CTD PMID:23939143 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846 		JBrowse link
G GZMB granzyme B increases expression
multiple interactions		 EXP Poly I-C results in increased expression of GZMB mRNA; Poly I-C results in increased expression of GZMB protein
Particulate Matter inhibits the reaction [Poly I-C results in increased expression of GZMB mRNA]; Particulate Matter inhibits the reaction [Poly I-C results in increased expression of GZMB protein]; Vehicle Emissions inhibits the reaction [Poly I-C results in increased expression of GZMB mRNA]; Vehicle Emissions inhibits the reaction [Poly I-C results in increased expression of GZMB protein]		 CTD PMID:23618096 NCBI chr14:24,630,954...24,634,190
Ensembl chr14:24,630,954...24,634,267 		JBrowse link
G HEY2 hes related family bHLH transcription factor with YRPW motif 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of HEY2 mRNA CTD PMID:26923065 NCBI chr 6:125,749,632...125,761,269
Ensembl chr 6:125,747,664...125,761,269 		JBrowse link
G HMGB1 high mobility group box 1 multiple interactions EXP Indoprofen inhibits the reaction [Poly I-C results in increased secretion of and affects the localization of HMGB1 protein]; Poly I-C results in increased secretion of and affects the localization of HMGB1 protein CTD PMID:34755645 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions
increases expression		 ISO Diclofenac promotes the reaction [Poly I-C results in increased expression of HMOX1 mRNA] CTD PMID:23939143 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 increases expression ISO Poly I-C results in increased expression of HSP90AA1 mRNA CTD PMID:23939143 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A increases expression ISO Poly I-C results in increased expression of HSPA1A mRNA CTD PMID:23939143 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 increases expression ISO Poly I-C results in increased expression of HSPA8 mRNA CTD PMID:23939143 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230 		JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A increases expression ISO Poly I-C results in increased expression of HTR2A mRNA CTD PMID:24889602 NCBI chr13:46,831,546...46,898,082
Ensembl chr13:46,831,546...46,897,076 		JBrowse link
G IBTK inhibitor of Bruton tyrosine kinase multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of IBTK mRNA CTD PMID:26923065 NCBI chr 6:82,169,987...82,247,744
Ensembl chr 6:82,169,986...82,247,754 		JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 increases expression
multiple interactions		 EXP Poly I-C results in increased expression of IDO1 mRNA
poly(I:C) co-treated with tryptophan or alone increases activity and expression of IDO1 protein in Langerhans cell-like dendritic cells		 CTD
RGD		 PMID:27783115 PMID:26198597 RGD:11528429 NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790 		JBrowse link
G IDO2 indoleamine 2,3-dioxygenase 2 increases expression EXP Poly I-C results in increased expression of IDO2 mRNA CTD PMID:27783115 NCBI chr 8:39,934,651...40,016,392
Ensembl chr 8:39,934,614...40,016,392 		JBrowse link
G IFIH1 interferon induced with helicase C domain 1 multiple interactions
increases expression		 EXP IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of IFIH1 mRNA]; Nicotine inhibits the reaction [Poly I-C results in increased expression of IFIH1 mRNA] CTD PMID:30341573 PMID:31154625 NCBI chr 2:162,267,074...162,318,684
Ensembl chr 2:162,267,074...162,318,684 		JBrowse link
G IFIT1 interferon induced protein with tetratricopeptide repeats 1 increases expression
multiple interactions		 EXP Poly I-C results in increased expression of IFIT1 mRNA
IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of IFIT1 mRNA]; Nicotine inhibits the reaction [Poly I-C results in increased expression of IFIT1 mRNA]		 CTD PMID:31154625 NCBI chr10:89,392,623...89,406,487
Ensembl chr10:89,392,546...89,406,487 		JBrowse link
G IFIT2 interferon induced protein with tetratricopeptide repeats 2 increases expression
multiple interactions		 EXP Poly I-C results in increased expression of IFIT2 mRNA
Acetylcysteine inhibits the reaction [Dieldrin inhibits the reaction [Poly I-C results in increased expression of IFIT2 mRNA]]; Dieldrin inhibits the reaction [Poly I-C results in increased expression of IFIT2 mRNA]		 CTD PMID:34051100 NCBI chr10:89,302,046...89,309,271
Ensembl chr10:89,283,694...89,309,271 		JBrowse link
G IFITM1 interferon induced transmembrane protein 1 increases expression EXP Poly I-C results in increased expression of IFITM1 mRNA CTD PMID:22240577 NCBI chr11:314,040...315,272
Ensembl chr11:310,041...315,272 		JBrowse link
G IFNA1 interferon alpha 1 increases expression ISO Poly I-C results in increased expression of IFNA1 mRNA CTD PMID:28726298 NCBI chr 9:21,440,439...21,441,316
Ensembl chr 9:21,440,439...21,441,316 		JBrowse link
G IFNB1 interferon beta 1 increases expression
increases secretion
multiple interactions		 EXP
ISO		 Poly I-C results in increased expression of IFNB1 mRNA; Poly I-C results in increased expression of IFNB1 protein
Poly I-C results in increased secretion of IFNB1 protein
MIR26A mRNA inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]
apilimod inhibits the reaction [Poly I-C results in increased secretion of IFNB1 protein]; APPL1 protein promotes the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; BX795 inhibits the reaction [Poly I-C results in increased expression of IFNB1 protein]; Luteolin inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; pitavastatin inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; Pravastatin inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; Progesterone inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; Resveratrol inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; sodium arsenite inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; sodium arsenite inhibits the reaction [Poly I-C results in increased secretion of IFNB1 protein]; Sodium Selenite inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; trametinib promotes the reaction [Poly I-C results in increased expression of IFNB1 mRNA]
[Dronabinol co-treated with Cannabidiol] inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; [Vehicle Emissions analog co-treated with Poly I-C] results in increased expression of IFNB1 mRNA; Cannabidiol inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; Dronabinol inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; IRF7 protein affects the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; IRF7 protein mutant form affects the reaction [Nicotine inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]]; IRF7 protein mutant form inhibits the reaction [Nicotine inhibits the reaction [Poly I-C results in increased secretion of IFNB1 protein]]; IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased secretion of IFNB1 protein]; Nicotine inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; Nicotine inhibits the reaction [Poly I-C results in increased secretion of IFNB1 protein]; Smoke inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; TLR3 protein affects the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; TP53 protein affects the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; Wortmannin inhibits the reaction [[Vehicle Emissions analog co-treated with Poly I-C] results in increased expression of IFNB1 mRNA]		 CTD PMID:16116226 PMID:16399790 PMID:17669408 PMID:18279804 PMID:18323514 More... NCBI chr 9:21,077,104...21,077,942
Ensembl chr 9:21,077,104...21,077,942 		JBrowse link
G IFNG interferon gamma multiple interactions
increases secretion
increases expression		 EXP
ISO		 [Poly I-C co-treated with IFNG protein] results in increased secretion of CD40 protein; [Poly I-C co-treated with IFNG protein] results in increased secretion of CD86 protein; Smoke inhibits the reaction [Poly I-C results in increased expression of IFNG mRNA]
Poly I-C results in increased secretion of IFNG protein
Ethanol inhibits the reaction [Poly I-C results in increased expression of IFNG protein]
Poly I-C results in increased expression of IFNG mRNA; Poly I-C results in increased expression of IFNG protein		 CTD PMID:9328138 PMID:16224278 PMID:17321468 PMID:19500611 PMID:23618096 More... NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IFNL1 interferon lambda 1 increases expression
multiple interactions		 EXP Poly I-C results in increased expression of IFNL1 mRNA
Smoke inhibits the reaction [Poly I-C results in increased expression of IFNL1 mRNA]		 CTD PMID:35817128 NCBI chr19:39,296,407...39,298,673
Ensembl chr19:39,296,407...39,298,673 		JBrowse link
G IGF1 insulin like growth factor 1 multiple interactions
decreases expression		 ISO IL6 protein affects the reaction [Poly I-C results in decreased expression of IGF1 protein]
Poly I-C results in decreased expression of IGF1 mRNA; Poly I-C results in decreased expression of IGF1 protein		 CTD PMID:1705203 PMID:21195166 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 multiple interactions
decreases expression		 ISO IL6 protein affects the reaction [Poly I-C results in decreased expression of IGFBP3 protein] CTD PMID:21195166 NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874 		JBrowse link
G IGSF6 immunoglobulin superfamily member 6 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of IGSF6 mRNA CTD PMID:26923065 NCBI chr16:21,639,550...21,652,608
Ensembl chr16:21,639,550...21,652,608 		JBrowse link
G IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon multiple interactions
increases phosphorylation		 ISO APPL1 protein promotes the reaction [Poly I-C results in increased phosphorylation of IKBKE protein] CTD PMID:25780039 NCBI chr 1:206,470,476...206,496,889
Ensembl chr 1:206,470,476...206,496,889 		JBrowse link
G IL10 interleukin 10 multiple interactions
increases expression
increases secretion		 EXP
ISO		 CEP-11004 inhibits the reaction [Poly I-C results in increased secretion of IL10 protein]; SB 203580 inhibits the reaction [Poly I-C results in increased secretion of IL10 protein]
Poly I-C results in increased expression of IL10 mRNA
Poly I-C results in increased expression of IL10 mRNA; Poly I-C results in increased expression of IL10 protein
Citrinin inhibits the reaction [Poly I-C results in increased expression of IL10 mRNA]; Citrinin inhibits the reaction [Poly I-C results in increased expression of IL10 protein]		 CTD PMID:16224278 PMID:17698565 PMID:22771370 PMID:23618096 PMID:23939143 More... NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL12A interleukin 12A multiple interactions
increases expression		 EXP 6-formylindolo(3,2-b)carbazole inhibits the reaction [Poly I-C results in increased expression of IL12A mRNA]; indole-3-carbinol inhibits the reaction [Poly I-C results in increased expression of IL12A mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [Poly I-C results in increased expression of IL12A mRNA] CTD PMID:27783115 NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019 		JBrowse link
G IL12B interleukin 12B multiple interactions
increases expression		 EXP
ISO		 [[Poly I-C binds to and results in increased activity of TLR3 protein] which co-treated with Nanotubes, Carbon] results in increased secretion of IL12B protein; Particulate Matter analog inhibits the reaction [Poly I-C results in increased expression of IL12B protein]; Vehicle Emissions analog inhibits the reaction [Poly I-C results in increased expression of IL12B protein]
Poly I-C results in increased expression of IL12B mRNA; Poly I-C results in increased expression of IL12B protein
Ethanol inhibits the reaction [Poly I-C results in increased expression of IL12B protein]; Luteolin inhibits the reaction [Poly I-C results in increased expression of IL12B mRNA]		 CTD PMID:16890772 PMID:19426678 PMID:19500611 PMID:23266719 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G IL17A interleukin 17A increases expression ISO Poly I-C results in increased expression of IL17A protein CTD PMID:30836164 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL1B interleukin 1 beta multiple interactions
increases secretion
increases expression		 ISO
EXP		 APPL1 protein inhibits the reaction [Poly I-C results in increased expression of IL1B protein]; Citrinin inhibits the reaction [Poly I-C results in increased expression of IL1B mRNA]; Ethanol inhibits the reaction [Poly I-C results in increased expression of IL1B protein]; Poly I-C promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]
Poly I-C results in increased secretion of IL1B protein
2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane promotes the reaction [Poly I-C results in increased expression of IL1B protein]; 4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol promotes the reaction [Poly I-C results in increased expression of IL1B protein]; 6-formylindolo(3,2-b)carbazole promotes the reaction [Poly I-C results in increased expression of IL1B mRNA]; Estradiol promotes the reaction [Poly I-C results in increased expression of IL1B protein]; Tetrachlorodibenzodioxin promotes the reaction [Poly I-C results in increased expression of IL1B mRNA]
Poly I-C results in increased expression of IL1B mRNA; Poly I-C results in increased expression of IL1B protein		 CTD PMID:16687389 PMID:17321468 PMID:19500611 PMID:22771370 PMID:23618096 More... NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL2 interleukin 2 increases expression
increases secretion		 ISO
EXP		 Poly I-C results in increased expression of IL2 mRNA
Poly I-C results in increased secretion of IL2 protein		 CTD PMID:9328138 PMID:23618096 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL27 interleukin 27 increases expression
multiple interactions		 ISO Poly I-C results in increased expression of IL27 mRNA
Luteolin inhibits the reaction [Poly I-C results in increased expression of IL27 mRNA]		 CTD PMID:19426678 NCBI chr16:28,499,362...28,506,834
Ensembl chr16:28,499,362...28,512,051 		JBrowse link
G IL33 interleukin 33 multiple interactions
increases expression		 EXP
ISO		 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane promotes the reaction [Poly I-C results in increased expression of IL33 protein]; 4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol promotes the reaction [Poly I-C results in increased expression of IL33 protein]; Estradiol promotes the reaction [Poly I-C results in increased expression of IL33 protein]
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Poly I-C results in increased expression of IL33 protein]		 CTD PMID:25747661 PMID:30017638 NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983 		JBrowse link
G IL4 interleukin 4 multiple interactions
increases expression
increases secretion
increases response to substance		 EXP
ISO		 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; 4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol promotes the reaction [Poly I-C results in increased expression of IL4 protein]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; [Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2; [Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2; [Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein; [Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA; [Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA; [Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA; [Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein; [Poly I-C co-treated with IL4 protein] results in increased secretion of Dinoprost; [Poly I-C co-treated with IL4 protein] results in increased secretion of Dinoprostone; [Poly I-C co-treated with IL4 protein] results in increased secretion of Thromboxane B2; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Thromboxane B2]; amorolfine promotes the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Dinoprostone]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Thromboxane B2]; butenafine promotes the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Dinoprostone]; Estradiol promotes the reaction [Poly I-C results in increased expression of IL4 protein]; helenalin inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; helenalin inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; helenalin inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; helenalin inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; IL4 protein promotes the reaction [Poly I-C results in increased expression of CCL5 mRNA]; IL4 protein promotes the reaction [Poly I-C results in increased expression of CXCL8 mRNA]; IL4 protein promotes the reaction [Poly I-C results in increased expression of TSLP mRNA]; IL4 protein promotes the reaction [Poly I-C results in increased expression of TSLP protein]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Thromboxane B2]; Itraconazole promotes the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Dinoprostone]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Thromboxane B2]; Ketoconazole promotes the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Dinoprostone]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Thromboxane B2]; luliconazole promotes the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Dinoprostone]; Particulate Matter inhibits the reaction [Poly I-C results in increased secretion of IL4 protein]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Thromboxane B2]; Terbinafine promotes the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Dinoprostone]; Vehicle Emissions inhibits the reaction [Poly I-C results in increased secretion of IL4 protein]
IL4 protein results in increased susceptibility to Poly I-C		 CTD PMID:23618096 PMID:23688403 PMID:30017638 PMID:30836164 PMID:34740670 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL6 interleukin 6 multiple interactions
increases secretion
increases expression		 EXP
ISO		 [Vehicle Emissions analog co-treated with Poly I-C] results in increased secretion of IL6 protein; CEP-11004 inhibits the reaction [Poly I-C results in increased secretion of IL6 protein]; Particulate Matter promotes the reaction [Poly I-C results in increased expression of IL6]; SB 203580 inhibits the reaction [Poly I-C results in increased secretion of IL6 protein]; Smoke inhibits the reaction [Poly I-C results in increased secretion of IL6 protein]; TLR3 mRNA promotes the reaction [Poly I-C results in increased expression of IL6 mRNA]; TRAF6 mutant form inhibits the reaction [Vehicle Emissions analog promotes the reaction [Poly I-C results in increased expression of IL6 mRNA]]; Vehicle Emissions analog promotes the reaction [Poly I-C results in increased expression of IL6 mRNA]; Vehicle Emissions promotes the reaction [Poly I-C results in increased expression of IL6]
Poly I-C results in increased expression of IL6 mRNA; Poly I-C results in increased expression of IL6 protein
Ethanol inhibits the reaction [Poly I-C results in increased expression of IL6 protein]; IL6 protein affects the reaction [Poly I-C results in decreased expression of IGF1 protein]; IL6 protein affects the reaction [Poly I-C results in decreased expression of IGFBP3 protein]; IL6 protein affects the reaction [Poly I-C results in increased expression of PRL2B1 mRNA]; IL6 protein affects the reaction [Poly I-C results in increased phosphorylation of and results in increased activity of STAT3 protein]; Luteolin inhibits the reaction [Poly I-C results in increased expression of IL6 mRNA]; pitavastatin inhibits the reaction [Poly I-C results in increased expression of IL6 mRNA]; Poly I-C promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Pravastatin inhibits the reaction [Poly I-C results in increased expression of IL6 mRNA]; sodium arsenite inhibits the reaction [Poly I-C results in increased expression of IL6 mRNA]
Poly I-C results in increased expression of IL6; Poly I-C results in increased expression of IL6 mRNA		 CTD PMID:9328138 PMID:16399790 PMID:16687389 PMID:17698565 PMID:18323514 More... NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IRF3 interferon regulatory factor 3 increases phosphorylation
affects localization
multiple interactions		 EXP
ISO		 Poly I-C results in increased phosphorylation of IRF3 protein
Poly I-C affects the localization of IRF3 protein
APPL1 protein promotes the reaction [Poly I-C results in increased phosphorylation of IRF3 protein]; BX795 inhibits the reaction [Poly I-C results in increased phosphorylation of IRF3 protein]; Chloroquine inhibits the reaction [Poly I-C results in increased phosphorylation of IRF3 protein]; chrysin inhibits the reaction [Poly I-C results in increased expression of IRF3 mRNA]; DNM2 protein promotes the reaction [Poly I-C results in increased phosphorylation of IRF3 protein]; eriodictyol inhibits the reaction [Poly I-C results in increased expression of IRF3 mRNA]; Quercetin inhibits the reaction [Poly I-C results in increased expression of IRF3 mRNA]; Sodium Selenite inhibits the reaction [Poly I-C results in increased activity of IRF3 protein]
[Dronabinol co-treated with Cannabidiol] inhibits the reaction [Poly I-C affects the localization of IRF3 protein]; [Vehicle Emissions analog co-treated with Poly I-C] affects the localization of IRF3 protein; Cannabidiol inhibits the reaction [Poly I-C affects the localization of IRF3 protein]; Dronabinol inhibits the reaction [Poly I-C results in increased localization of IRF3 protein]; TP53 protein affects the reaction [Poly I-C results in increased phosphorylation of IRF3 protein]		 CTD PMID:16399790 PMID:18279804 PMID:18779317 PMID:19426678 PMID:25780039 More... NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875 		JBrowse link
G IRF7 interferon regulatory factor 7 increases expression
multiple interactions		 EXP
ISO		 Poly I-C results in increased expression of IRF7 mRNA
cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester inhibits the reaction [Poly I-C results in increased expression of IRF7 mRNA]
IRF7 protein affects the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; IRF7 protein mutant form affects the reaction [Nicotine inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]]; IRF7 protein mutant form inhibits the reaction [Nicotine inhibits the reaction [Poly I-C results in increased secretion of IFNB1 protein]]; IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of IFIH1 mRNA]; IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of IFIT1 mRNA]; IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of IRF7 mRNA]; IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of IRF9 mRNA]; IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of ISG15 mRNA]; IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of OAS1 mRNA]; IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of RIGI mRNA]; IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of STAT1 mRNA]; IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of STAT2 mRNA]; IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased secretion of IFNB1 protein]; Nicotine inhibits the reaction [Poly I-C results in increased expression of IRF7 mRNA]		 CTD PMID:22240577 PMID:28726298 PMID:31154625 NCBI chr11:612,555...615,950
Ensembl chr11:612,553...615,983 		JBrowse link
G IRF9 interferon regulatory factor 9 increases expression
multiple interactions		 EXP Poly I-C results in increased expression of IRF9 mRNA
IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of IRF9 mRNA]		 CTD PMID:22240577 PMID:31154625 NCBI chr14:24,161,265...24,166,565
Ensembl chr14:24,161,234...24,168,043 		JBrowse link
G ISG15 ISG15 ubiquitin like modifier increases expression
multiple interactions		 EXP
ISO		 Poly I-C results in increased expression of ISG15 mRNA
IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of ISG15 mRNA]; Nicotine inhibits the reaction [Poly I-C results in increased expression of ISG15 mRNA]		 CTD PMID:31154625 PMID:36958387 NCBI chr 1:1,013,497...1,014,540
Ensembl chr 1:1,001,138...1,014,540 		JBrowse link
G ITGAM integrin subunit alpha M increases expression ISO Poly I-C results in increased expression of ITGAM mRNA; Poly I-C results in increased expression of ITGAM protein CTD PMID:27317300 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892 		JBrowse link
G JCAD junctional cadherin 5 associated multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of JCAD mRNA CTD PMID:26923065 NCBI chr10:30,012,803...30,115,494
Ensembl chr10:30,012,803...30,115,494 		JBrowse link
G KCNA2 potassium voltage-gated channel subfamily A member 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of KCNA2 mRNA CTD PMID:26923065 NCBI chr 1:110,593,580...110,631,440
Ensembl chr 1:110,519,837...110,631,474 		JBrowse link
G KCNIP4 potassium voltage-gated channel interacting protein 4 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of KCNIP4 mRNA CTD PMID:26923065 NCBI chr 4:20,728,606...21,948,772
Ensembl chr 4:20,728,606...21,948,772 		JBrowse link
G KCNQ5 potassium voltage-gated channel subfamily Q member 5 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of KCNQ5 mRNA CTD PMID:26923065 NCBI chr 6:72,622,064...73,198,853
Ensembl chr 6:72,621,792...73,198,853 		JBrowse link
G KIF5B kinesin family member 5B multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of KIF5B mRNA CTD PMID:26923065 NCBI chr10:32,009,015...32,056,425
Ensembl chr10:32,009,015...32,056,425 		JBrowse link
G KIF5C kinesin family member 5C multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of KIF5C mRNA CTD PMID:26923065 NCBI chr 2:148,875,227...149,026,759
Ensembl chr 2:148,875,227...149,026,759 		JBrowse link
G KLF4 KLF transcription factor 4 multiple interactions
increases expression		 EXP Poly I-C promotes the reaction [MSI1 protein results in increased expression of KLF4 protein]
Poly I-C results in increased expression of KLF4 protein		 CTD PMID:29486283 NCBI chr 9:107,484,852...107,489,769
Ensembl chr 9:107,484,852...107,490,482 		JBrowse link
G KLRK1 killer cell lectin like receptor K1 increases expression ISO Poly I-C results in increased expression of KLRK1 mRNA; Poly I-C results in increased expression of KLRK1 protein CTD PMID:16472598 NCBI chr12:10,372,353...10,390,041
Ensembl chr12:10,372,353...10,391,874 		JBrowse link
G KPNA3 karyopherin subunit alpha 3 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of KPNA3 mRNA CTD PMID:26923065 NCBI chr13:49,699,320...49,792,682
Ensembl chr13:49,699,320...49,792,682 		JBrowse link
G KPNA7 karyopherin subunit alpha 7 increases expression
multiple interactions		 EXP Poly I-C results in increased expression of KPNA7 mRNA
Atorvastatin inhibits the reaction [Poly I-C results in increased expression of KPNA7 mRNA]; Ivermectin inhibits the reaction [Poly I-C results in increased expression of KPNA7 mRNA]		 CTD PMID:34696514 NCBI chr 7:99,145,804...99,219,419
Ensembl chr 7:99,173,572...99,250,075 		JBrowse link
G LSM14B LSM family member 14B multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of LSM14B mRNA CTD PMID:26923065 NCBI chr20:62,122,475...62,135,374
Ensembl chr20:62,122,461...62,135,374 		JBrowse link
G MAL2 mal, T cell differentiation protein 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of MAL2 mRNA CTD PMID:26923065 NCBI chr 8:119,208,363...119,245,673
Ensembl chr 8:119,165,034...119,245,673 		JBrowse link
G MAP3K11 mitogen-activated protein kinase kinase kinase 11 increases phosphorylation EXP Poly I-C results in increased phosphorylation of MAP3K11 protein CTD PMID:17698565 NCBI chr11:65,597,757...65,614,221
Ensembl chr11:65,597,756...65,615,382 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 decreases phosphorylation
increases phosphorylation
multiple interactions		 ISO Poly I-C results in decreased phosphorylation of MAPK1 protein
Poly I-C results in increased phosphorylation of MAPK1 protein
Suramin inhibits the reaction [Poly I-C results in decreased phosphorylation of MAPK1 protein]; trametinib inhibits the reaction [Poly I-C results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Poly I-C results in increased phosphorylation of MAPK1 protein]		 CTD PMID:23516405 PMID:25780039 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 decreases phosphorylation
increases phosphorylation
multiple interactions		 ISO Poly I-C results in decreased phosphorylation of MAPK3 protein
Poly I-C results in increased phosphorylation of MAPK3 protein
Suramin inhibits the reaction [Poly I-C results in decreased phosphorylation of MAPK3 protein]; trametinib inhibits the reaction [Poly I-C results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Poly I-C results in increased phosphorylation of MAPK3 protein]		 CTD PMID:23516405 PMID:25780039 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK4 mitogen-activated protein kinase 4 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of MAPK4 mRNA CTD PMID:26923065 NCBI chr18:50,559,612...50,731,826
Ensembl chr18:50,560,087...50,731,826 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of MAPK9 mRNA CTD PMID:26923065 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099 		JBrowse link
G MAPRE1 microtubule associated protein RP/EB family member 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of MAPRE1 mRNA CTD PMID:26923065 NCBI chr20:32,819,777...32,850,405
Ensembl chr20:32,819,954...32,850,405 		JBrowse link
G MARCHF7 membrane associated ring-CH-type finger 7 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of MARCHF7 mRNA CTD PMID:26923065 NCBI chr 2:159,712,506...159,771,027
Ensembl chr 2:159,712,457...159,771,027 		JBrowse link
G MBLAC2 metallo-beta-lactamase domain containing 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of MBLAC2 mRNA CTD PMID:26923065 NCBI chr 5:90,458,209...90,474,771
Ensembl chr 5:90,458,209...90,474,771 		JBrowse link
G MBP myelin basic protein multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of MBP mRNA CTD PMID:26923065 NCBI chr18:76,978,833...77,133,708
Ensembl chr18:76,978,827...77,133,683 		JBrowse link
G MEF2C myocyte enhancer factor 2C multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of MEF2C mRNA CTD PMID:26923065 NCBI chr 5:88,717,117...88,904,105
Ensembl chr 5:88,717,117...88,904,257 		JBrowse link
G MICOS13 mitochondrial contact site and cristae organizing system subunit 13 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of MICOS13 mRNA CTD PMID:26923065 NCBI chr19:5,678,422...5,680,516
Ensembl chr19:5,678,421...5,680,516 		JBrowse link
G MICU3 mitochondrial calcium uptake family member 3 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of MICU3 mRNA CTD PMID:26923065 NCBI chr 8:17,027,238...17,138,640
Ensembl chr 8:17,027,238...17,122,642 		JBrowse link
G MIR148B microRNA 148b multiple interactions EXP [Arsenicals co-treated with Poly I-C] results in decreased expression of MIR148B mRNA CTD PMID:34303791 NCBI chr12:54,337,216...54,337,314
Ensembl chr12:54,337,216...54,337,314 		JBrowse link
G MIR152 microRNA 152 multiple interactions EXP [Arsenicals co-treated with Poly I-C co-treated with Alitretinoin] results in decreased expression of MIR152 mRNA; [Arsenicals co-treated with Poly I-C] results in decreased expression of MIR152 mRNA CTD PMID:34303791 NCBI chr17:48,037,161...48,037,247
Ensembl chr17:48,037,161...48,037,247 		JBrowse link
G MIR155 microRNA 155 multiple interactions
increases expression		 ISO MIR155 mRNA inhibits the reaction [Progesterone inhibits the reaction [Poly I-C results in increased expression of MIR155 mRNA]]; Progesterone inhibits the reaction [Poly I-C results in increased expression of MIR155 mRNA] CTD PMID:22546503 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044 		JBrowse link
G MIR26A1 microRNA 26a-1 multiple interactions ISO MIR26A mRNA inhibits the reaction [Poly I-C results in increased activity of TLR3 protein]; MIR26A mRNA inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; MIR26A mRNA inhibits the reaction [Poly I-C results in increased expression of TNF mRNA]; MIR26A mRNA inhibits the reaction [Poly I-C results in increased expression of TNF protein] CTD PMID:24423102 NCBI chr 3:37,969,404...37,969,480
Ensembl chr 3:37,969,404...37,969,480 		JBrowse link
G MIR29C microRNA 29c multiple interactions EXP [Arsenicals co-treated with Poly I-C co-treated with Alitretinoin] results in decreased expression of MIR29C mRNA; [Arsenicals co-treated with Poly I-C] results in decreased expression of MIR29C mRNA CTD PMID:34303791 NCBI chr 1:207,801,852...207,801,939
Ensembl chr 1:207,801,852...207,801,939 		JBrowse link
G MRPS15 mitochondrial ribosomal protein S15 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of MRPS15 mRNA CTD PMID:26923065 NCBI chr 1:36,455,718...36,464,384
Ensembl chr 1:36,455,718...36,464,384 		JBrowse link
G MSI1 musashi RNA binding protein 1 multiple interactions EXP Poly I-C promotes the reaction [MSI1 protein results in increased expression of KLF4 protein]; Poly I-C promotes the reaction [MSI1 protein results in increased expression of MYC protein]; Poly I-C promotes the reaction [MSI1 protein results in increased expression of POU5F1 protein]; Poly I-C promotes the reaction [MSI1 protein results in increased expression of SOX2 protein] CTD PMID:29486283 NCBI chr12:120,339,662...120,369,164
Ensembl chr12:120,341,330...120,369,164 		JBrowse link
G MTPN myotrophin multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of MTPN mRNA CTD PMID:26923065 NCBI chr 7:135,926,760...135,977,359
Ensembl chr 7:135,926,760...135,977,359 		JBrowse link
G MTREX Mtr4 exosome RNA helicase multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of MTREX mRNA CTD PMID:26923065 NCBI chr 5:55,307,989...55,425,579
Ensembl chr 5:55,307,989...55,425,579 		JBrowse link
G MX1 MX dynamin like GTPase 1 increases expression
multiple interactions		 EXP Poly I-C results in increased expression of MX1 mRNA
Acetylcysteine inhibits the reaction [Dieldrin inhibits the reaction [Poly I-C results in increased expression of MX1 mRNA]]; Dieldrin inhibits the reaction [Poly I-C results in increased expression of MX1 mRNA]		 CTD PMID:17669408 PMID:22558189 PMID:34051100 NCBI chr21:41,420,558...41,459,214
Ensembl chr21:41,420,020...41,470,071 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor increases expression
multiple interactions		 EXP Poly I-C results in increased expression of MYC protein
Poly I-C promotes the reaction [MSI1 protein results in increased expression of MYC protein]		 CTD PMID:29486283 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor increases expression
multiple interactions		 ISO Poly I-C results in increased expression of MYD88 mRNA
cinnamaldehyde inhibits the reaction [Poly I-C results in increased expression of MYD88 mRNA]		 CTD PMID:18306459 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G NAA60 N-alpha-acetyltransferase 60, NatF catalytic subunit multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of NAA60 mRNA CTD PMID:26923065 NCBI chr16:3,443,611...3,486,963
Ensembl chr16:3,443,649...3,486,953 		JBrowse link
G NAPB NSF attachment protein beta multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of NAPB mRNA CTD PMID:26923065 NCBI chr20:23,374,522...23,421,488
Ensembl chr20:23,374,519...23,421,519 		JBrowse link
G NAPEPLD N-acyl phosphatidylethanolamine phospholipase D multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of NAPEPLD mRNA CTD PMID:26923065 NCBI chr 7:103,099,776...103,150,001
Ensembl chr 7:103,099,776...103,149,560 		JBrowse link
G NBEA neurobeachin multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of NBEA mRNA CTD PMID:26923065 NCBI chr13:34,942,270...35,672,736
Ensembl chr13:34,942,270...35,673,022 		JBrowse link
G NDST3 N-deacetylase and N-sulfotransferase 3 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of NDST3 mRNA CTD PMID:26923065 NCBI chr 4:118,033,322...118,258,634
Ensembl chr 4:118,033,618...118,258,634 		JBrowse link
G NECAB1 N-terminal EF-hand calcium binding protein 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of NECAB1 mRNA CTD PMID:26923065 NCBI chr 8:90,791,775...90,959,393
Ensembl chr 8:90,791,741...90,959,393 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 increases expression
multiple interactions		 EXP Poly I-C results in increased expression of NFKB1 mRNA
[Ivermectin co-treated with Atorvastatin] inhibits the reaction [Poly I-C results in increased expression of NFKB1 mRNA]; Atorvastatin inhibits the reaction [Poly I-C results in increased expression of NFKB1 mRNA]; Ivermectin inhibits the reaction [Poly I-C results in increased expression of NFKB1 mRNA]		 CTD PMID:34696514 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NFKBIA NFKB inhibitor alpha increases phosphorylation
multiple interactions		 EXP Poly I-C results in increased phosphorylation of NFKBIA protein
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; [Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; N-(3,5-bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide inhibits the reaction [Poly I-C results in increased phosphorylation of NFKBIA protein]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; TP53 protein affects the reaction [Poly I-C results in increased phosphorylation of NFKBIA protein]		 CTD PMID:18779317 PMID:20932985 PMID:23688403 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NLGN3 neuroligin 3 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of NLGN3 mRNA CTD PMID:26923065 NCBI chr  X:71,144,841...71,175,307
Ensembl chr  X:71,144,821...71,175,255 		JBrowse link
G NMU neuromedin U multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of NMU mRNA CTD PMID:26923065 NCBI chr 4:55,595,231...55,636,793
Ensembl chr 4:55,595,229...55,636,698 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions
increases expression		 ISO pitavastatin inhibits the reaction [Poly I-C results in increased expression of NOS2 mRNA]; Pravastatin inhibits the reaction [Poly I-C results in increased expression of NOS2 mRNA]; sodium arsenite inhibits the reaction [Poly I-C results in increased expression of NOS2 mRNA]; sodium arsenite inhibits the reaction [Poly I-C results in increased expression of NOS2 protein]; Sodium Selenite inhibits the reaction [Poly I-C results in increased expression of NOS2 protein]
Diclofenac promotes the reaction [Poly I-C results in increased expression of NOS2 mRNA]
Poly I-C results in increased expression of NOS2 mRNA; Poly I-C results in increased expression of NOS2 protein		 CTD PMID:17321468 PMID:18279804 PMID:18323514 PMID:21195166 PMID:23939143 More... NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NRSN1 neurensin 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of NRSN1 mRNA CTD PMID:26923065 NCBI chr 6:24,126,215...24,147,530
Ensembl chr 6:24,126,186...24,154,900 		JBrowse link
G NUF2 NUF2 component of NDC80 kinetochore complex multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of NUF2 mRNA CTD PMID:26923065 NCBI chr 1:163,321,954...163,355,759
Ensembl chr 1:163,266,576...163,355,764 		JBrowse link
G OAS1 2'-5'-oligoadenylate synthetase 1 increases expression
multiple interactions		 EXP Poly I-C results in increased expression of OAS1 mRNA
[[Poly I-C co-treated with Interferon-alpha] results in increased activity of OAS1 protein] which results in increased abundance of 2',5'-oligoadenylate; [Poly I-C co-treated with Interferon-alpha] results in increased activity of OAS1 protein; IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of OAS1 mRNA]; Nicotine inhibits the reaction [Poly I-C results in increased expression of OAS1 mRNA]		 CTD PMID:17669408 PMID:22240577 PMID:26055709 PMID:31154625 NCBI chr12:112,906,962...112,933,219
Ensembl chr12:112,905,856...112,933,219 		JBrowse link
G OAS2 2'-5'-oligoadenylate synthetase 2 increases expression EXP Poly I-C results in increased expression of OAS2 mRNA CTD PMID:22240577 PMID:22558189 NCBI chr12:112,978,519...113,011,723
Ensembl chr12:112,978,395...113,011,723 		JBrowse link
G OR4E1 olfactory receptor family 4 subfamily E member 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of OR4E1 mRNA CTD PMID:26923065 NCBI chr14:21,667,886...21,673,818
Ensembl chr14:21,667,886...21,673,818 		JBrowse link
G P2RX7 purinergic receptor P2X 7 decreases expression
multiple interactions		 ISO Poly I-C results in decreased expression of P2RX7 protein
Suramin inhibits the reaction [Poly I-C results in decreased expression of P2RX7 protein]		 CTD PMID:23516405 NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032 		JBrowse link
G P2RY2 purinergic receptor P2Y2 decreases expression
multiple interactions		 ISO Poly I-C results in decreased expression of P2RY2 protein
Suramin inhibits the reaction [Poly I-C results in decreased expression of P2RY2 protein]		 CTD PMID:23516405 NCBI chr11:73,218,281...73,242,427
Ensembl chr11:73,218,281...73,242,427 		JBrowse link
G PAK2 p21 (RAC1) activated kinase 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of PAK2 mRNA CTD PMID:26923065 NCBI chr 3:196,739,857...196,832,647
Ensembl chr 3:196,739,857...196,832,647 		JBrowse link
G PARD6G par-6 family cell polarity regulator gamma multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of PARD6G mRNA CTD PMID:26923065 NCBI chr18:80,157,232...80,247,514
Ensembl chr18:80,157,232...80,247,514 		JBrowse link
G PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of PCMTD1 mRNA CTD PMID:26923065 NCBI chr 8:51,817,575...51,899,186
Ensembl chr 8:51,817,575...51,899,186 		JBrowse link
G PDAP1 PDGFA associated protein 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of PDAP1 mRNA CTD PMID:26923065 NCBI chr 7:99,394,673...99,408,597
Ensembl chr 7:99,392,048...99,408,597 		JBrowse link
G PDCD6IP programmed cell death 6 interacting protein multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of PDCD6IP mRNA CTD PMID:26923065 NCBI chr 3:33,798,630...33,869,703
Ensembl chr 3:33,798,571...33,869,707 		JBrowse link
G PHACTR1 phosphatase and actin regulator 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of PHACTR1 mRNA CTD PMID:26923065 NCBI chr 6:12,716,767...13,287,837
Ensembl chr 6:12,716,312...13,290,446 		JBrowse link
G PHF7 PHD finger protein 7 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of PHF7 mRNA CTD PMID:26923065 NCBI chr 3:52,410,660...52,423,641
Ensembl chr 3:52,410,660...52,423,641 		JBrowse link
G PKIB cAMP-dependent protein kinase inhibitor beta decreases expression
multiple interactions		 ISO Poly I-C results in decreased expression of PKIB mRNA
[Poly I-C co-treated with HU 211] results in decreased expression of PKIB mRNA		 CTD PMID:26923065 NCBI chr 6:122,471,921...122,726,373
Ensembl chr 6:122,471,917...122,726,373 		JBrowse link
G PLCB1 phospholipase C beta 1 increases expression ISO Poly I-C results in increased expression of PLCB1 mRNA CTD PMID:24889602 NCBI chr20:8,132,266...8,884,900
Ensembl chr20:8,077,251...8,968,360 		JBrowse link
G PLCXD2 phosphatidylinositol specific phospholipase C X domain containing 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of PLCXD2 mRNA CTD PMID:26923065 NCBI chr 3:111,674,676...111,727,007
Ensembl chr 3:111,674,676...111,846,447 		JBrowse link
G PLEKHA8 pleckstrin homology domain containing A8 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of PLEKHA8 mRNA CTD PMID:26923065 NCBI chr 7:30,028,412...30,130,483
Ensembl chr 7:30,027,404...30,130,483 		JBrowse link
G PLPPR4 phospholipid phosphatase related 4 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of PLPPR4 mRNA CTD PMID:26923065 NCBI chr 1:99,262,924...99,309,584
Ensembl chr 1:99,264,292...99,309,590 		JBrowse link
G PMVK phosphomevalonate kinase multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of PMVK mRNA CTD PMID:26923065 NCBI chr 1:154,924,740...154,942,658
Ensembl chr 1:154,924,740...154,936,719 		JBrowse link
G POU5F1 POU class 5 homeobox 1 multiple interactions
increases expression		 EXP Poly I-C promotes the reaction [MSI1 protein results in increased expression of POU5F1 protein]
Poly I-C results in increased expression of POU5F1 protein		 CTD PMID:29486283 NCBI chr 6:31,164,337...31,170,682
Ensembl chr 6:31,164,337...31,180,731 		JBrowse link
G PRF1 perforin 1 multiple interactions
increases expression		 EXP Particulate Matter inhibits the reaction [Poly I-C results in increased expression of PRF1 protein]; Vehicle Emissions inhibits the reaction [Poly I-C results in increased expression of PRF1 protein]
Poly I-C results in increased expression of PRF1 mRNA; Poly I-C results in increased expression of PRF1 protein		 CTD PMID:23618096 NCBI chr10:70,597,348...70,602,741
Ensembl chr10:70,597,348...70,602,759 		JBrowse link
G PRKCI protein kinase C iota multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of PRKCI mRNA CTD PMID:26923065 NCBI chr 3:170,222,424...170,305,977
Ensembl chr 3:170,222,424...170,305,977 		JBrowse link
G PRODH2 proline dehydrogenase 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of PRODH2 mRNA CTD PMID:26923065 NCBI chr19:35,799,988...35,812,845
Ensembl chr19:35,799,988...35,813,299 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions		 ISO Poly I-C results in increased expression of PTGS2 protein
[Poly I-C results in increased susceptibility to 4-iodo-2,5-dimethoxyphenylisopropylamine] which results in increased expression of PTGS2 mRNA; Poly I-C promotes the reaction [4-iodo-2,5-dimethoxyphenylisopropylamine results in increased expression of PTGS2 mRNA]; resveratrol inhibits the reaction [Poly I-C results in increased expression of PTGS2 protein]; Sodium Selenite inhibits the reaction [Poly I-C results in increased expression of PTGS2 protein]		 CTD PMID:16116226 PMID:18279804 PMID:24889602 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PVALB parvalbumin multiple interactions ISO [Poly I-C co-treated with Cannabidiol] results in increased expression of PVALB protein CTD PMID:31326506 NCBI chr22:36,800,703...36,819,499
Ensembl chr22:36,800,684...36,819,479 		JBrowse link
G RAC1 Rac family small GTPase 1 multiple interactions ISO
EXP		 [Poly I-C co-treated with HU 211] results in decreased expression of RAC1 mRNA
[Poly I-C co-treated with Atorvastatin] results in decreased expression of RAC1 mRNA; [Poly I-C co-treated with Ivermectin] results in decreased expression of RAC1 mRNA		 CTD PMID:26923065 PMID:34696514 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967 		JBrowse link
G RARB retinoic acid receptor beta multiple interactions EXP [Arsenicals co-treated with Poly I-C co-treated with Alitretinoin] results in decreased expression of RARB mRNA; [Arsenicals co-treated with Poly I-C co-treated with Alitretinoin] results in decreased expression of RARB protein; [Arsenicals co-treated with Poly I-C] affects the expression of RARB mRNA; [Arsenicals co-treated with Poly I-C] results in decreased expression of RARB protein CTD PMID:34303791 NCBI chr 3:24,829,321...25,597,932
Ensembl chr 3:24,687,887...25,597,932 		JBrowse link
G RDM1 RAD52 motif containing 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of RDM1 mRNA CTD PMID:26923065 NCBI chr17:35,918,080...35,930,773
Ensembl chr17:35,918,066...35,930,773 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit affects localization
increases phosphorylation
multiple interactions		 EXP Poly I-C affects the localization of RELA protein
Poly I-C results in increased phosphorylation of RELA protein
TP53 protein affects the reaction [Poly I-C affects the localization of RELA protein]		 CTD PMID:18779317 PMID:24709138 PMID:27836898 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RGS4 regulator of G protein signaling 4 increases expression ISO Poly I-C results in increased expression of RGS4 mRNA CTD PMID:24889602 NCBI chr 1:163,068,871...163,076,802
Ensembl chr 1:163,068,775...163,076,802 		JBrowse link
G RHOA ras homolog family member A multiple interactions EXP [Poly I-C co-treated with Atorvastatin co-treated with Ivermectin] results in increased expression of RHOA mRNA; [Poly I-C co-treated with Atorvastatin] results in increased expression of RHOA mRNA CTD PMID:34696514 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998 		JBrowse link
G RIGI RNA sensor RIG-I increases expression
multiple interactions		 EXP Poly I-C results in increased expression of RIGI mRNA
IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of RIGI mRNA]; Nicotine inhibits the reaction [Poly I-C results in increased expression of RIGI mRNA]		 CTD PMID:27183587 PMID:30341573 PMID:31154625 NCBI chr 9:32,455,302...32,526,196
Ensembl chr 9:32,455,302...32,526,208 		JBrowse link
G RIMBP2 RIMS binding protein 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of RIMBP2 mRNA CTD PMID:26923065 NCBI chr12:130,396,133...130,716,299
Ensembl chr12:130,396,133...130,768,228 		JBrowse link
G RIMOC1 RAB7A interacting MON1-CCZ1 complex subunit 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of RIMOC1 mRNA CTD PMID:26923065 NCBI chr 5:41,904,344...41,921,636
Ensembl chr 5:41,904,188...41,921,636 		JBrowse link
G RNF141 ring finger protein 141 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of RNF141 mRNA CTD PMID:26923065 NCBI chr11:10,511,673...10,541,187
Ensembl chr11:10,511,673...10,541,230 		JBrowse link
G RPL31 ribosomal protein L31 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of RPL31 mRNA CTD PMID:26923065 NCBI chr 2:101,002,289...101,019,724
Ensembl chr 2:101,002,229...101,024,032 		JBrowse link
G RPS6KB2 ribosomal protein S6 kinase B2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of RPS6KB2 mRNA CTD PMID:26923065 NCBI chr11:67,428,494...67,435,401
Ensembl chr11:67,428,460...67,435,401 		JBrowse link
G RTN4RL1 reticulon 4 receptor like 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of RTN4RL1 mRNA CTD PMID:26923065 NCBI chr17:1,934,677...2,025,334
Ensembl chr17:1,934,677...2,025,334 		JBrowse link
G S100A3 S100 calcium binding protein A3 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of S100A3 mRNA CTD PMID:26923065 NCBI chr 1:153,547,329...153,549,258
Ensembl chr 1:153,547,329...153,549,258 		JBrowse link
G SEMA6D semaphorin 6D multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SEMA6D mRNA CTD PMID:26923065 NCBI chr15:47,184,089...47,774,228
Ensembl chr15:47,184,101...47,774,228 		JBrowse link
G SEPTIN6 septin 6 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SEPTIN6 mRNA CTD PMID:26923065 NCBI chr  X:119,615,724...119,693,168
Ensembl chr  X:119,615,724...119,693,370 		JBrowse link
G SERPINE1 serpin family E member 1 increases expression
multiple interactions		 EXP Poly I-C results in increased expression of SERPINE1 mRNA; Poly I-C results in increased expression of SERPINE1 protein
Chloroquine inhibits the reaction [Poly I-C results in increased expression of SERPINE1 mRNA]; Chloroquine inhibits the reaction [Poly I-C results in increased expression of SERPINE1 protein]; Hydroxychloroquine inhibits the reaction [Poly I-C results in increased expression of SERPINE1 mRNA]; Hydroxychloroquine inhibits the reaction [Poly I-C results in increased expression of SERPINE1 protein]; TLR3 mRNA promotes the reaction [Poly I-C results in increased expression of SERPINE1 mRNA]		 CTD PMID:30341573 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SESN2 sestrin 2 increases expression ISO Poly I-C results in increased expression of SESN2 mRNA CTD PMID:25637945 NCBI chr 1:28,259,518...28,282,491
Ensembl chr 1:28,259,518...28,282,491 		JBrowse link
G SGTB small glutamine rich tetratricopeptide repeat co-chaperone beta multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SGTB mRNA CTD PMID:26923065 NCBI chr 5:65,665,928...65,723,013
Ensembl chr 5:65,665,928...65,723,035 		JBrowse link
G SH3RF1 SH3 domain containing ring finger 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SH3RF1 mRNA CTD PMID:26923065 NCBI chr 4:169,094,259...169,270,956
Ensembl chr 4:169,094,259...169,270,956 		JBrowse link
G SHROOM2 shroom family member 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SHROOM2 mRNA CTD PMID:26923065 NCBI chr  X:9,786,429...9,949,443
Ensembl chr  X:9,786,429...9,949,443 		JBrowse link
G SIDT1 SID1 transmembrane family member 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SIDT1 mRNA CTD PMID:26923065 NCBI chr 3:113,532,555...113,637,111
Ensembl chr 3:113,532,555...113,629,575 		JBrowse link
G SLC14A1 solute carrier family 14 member 1 (Kidd blood group) multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SLC14A1 mRNA CTD PMID:26923065 NCBI chr18:45,724,181...45,752,520
Ensembl chr18:45,687,025...45,752,520 		JBrowse link
G SLC17A7 solute carrier family 17 member 7 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SLC17A7 mRNA CTD PMID:26923065 NCBI chr19:49,429,401...49,441,527
Ensembl chr19:49,429,401...49,442,360 		JBrowse link
G SLC25A12 solute carrier family 25 member 12 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SLC25A12 mRNA CTD PMID:26923065 NCBI chr 2:171,783,405...171,894,244
Ensembl chr 2:171,783,405...171,999,859 		JBrowse link
G SLC25A14 solute carrier family 25 member 14 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SLC25A14 mRNA CTD PMID:26923065 NCBI chr  X:130,339,919...130,373,357
Ensembl chr  X:130,339,888...130,373,361 		JBrowse link
G SLC2A13 solute carrier family 2 member 13 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SLC2A13 mRNA CTD PMID:26923065 NCBI chr12:39,755,025...40,106,081
Ensembl chr12:39,755,025...40,106,089 		JBrowse link
G SLC3A1 solute carrier family 3 member 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SLC3A1 mRNA CTD PMID:26923065 NCBI chr 2:44,275,480...44,322,437
Ensembl chr 2:44,275,458...44,321,494 		JBrowse link
G SLC4A10 solute carrier family 4 member 10 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SLC4A10 mRNA CTD PMID:26923065 NCBI chr 2:161,624,416...161,985,270
Ensembl chr 2:161,424,332...161,985,282 		JBrowse link
G SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SMARCD1 mRNA CTD PMID:26923065 NCBI chr12:50,085,342...50,100,707
Ensembl chr12:50,085,200...50,100,707 		JBrowse link
G SND1 staphylococcal nuclease and tudor domain containing 1 affects localization EXP Poly I-C affects the localization of SND1 protein CTD PMID:22240577 NCBI chr 7:127,652,194...128,092,593
Ensembl chr 7:127,652,194...128,092,609 		JBrowse link
G SNRK SNF related kinase multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SNRK mRNA CTD PMID:26923065 NCBI chr 3:43,286,540...43,351,143
Ensembl chr 3:43,286,512...43,424,764 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 increases expression
multiple interactions		 ISO Poly I-C results in increased expression of SOCS1 mRNA
Progesterone promotes the reaction [Poly I-C results in increased expression of SOCS1 mRNA]		 CTD PMID:22546503 NCBI chr16:11,254,417...11,256,204
Ensembl chr16:11,254,417...11,256,204 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 increases expression ISO Poly I-C results in increased expression of SOCS3 mRNA CTD PMID:21195166 NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077 		JBrowse link
G SOD2 superoxide dismutase 2 increases expression ISO Poly I-C results in increased expression of SOD2 mRNA CTD PMID:23939143 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SOX2 SRY-box transcription factor 2 multiple interactions
increases expression		 EXP Poly I-C promotes the reaction [MSI1 protein results in increased expression of SOX2 protein]
Poly I-C results in increased expression of SOX2 protein		 CTD PMID:29486283 NCBI chr 3:181,711,925...181,714,436
Ensembl chr 3:181,711,925...181,714,436 		JBrowse link
G SPAG6 sperm associated antigen 6 decreases expression ISO Poly I-C results in decreased expression of SPAG6 mRNA CTD PMID:26923065 NCBI chr10:22,345,496...22,417,610
Ensembl chr10:22,345,445...22,454,224 		JBrowse link
G SRSF12 serine and arginine rich splicing factor 12 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SRSF12 mRNA CTD PMID:26923065 NCBI chr 6:89,095,959...89,118,071
Ensembl chr 6:89,095,959...89,118,071 		JBrowse link
G SRSF7 serine and arginine rich splicing factor 7 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SRSF7 mRNA CTD PMID:26923065 NCBI chr 2:38,743,599...38,751,494
Ensembl chr 2:38,743,599...38,751,494 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 multiple interactions
increases expression
increases phosphorylation		 ISO
EXP		 sodium arsenite inhibits the reaction [Poly I-C results in increased phosphorylation of STAT1 protein]
Poly I-C results in increased expression of STAT1 mRNA
IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of STAT1 mRNA]; Nicotine inhibits the reaction [Poly I-C results in increased expression of STAT1 mRNA]		 CTD PMID:30726814 PMID:31154625 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960 		JBrowse link
G STAT2 signal transducer and activator of transcription 2 multiple interactions
increases expression		 EXP IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of STAT2 mRNA] CTD PMID:31154625 NCBI chr12:56,341,597...56,360,107
Ensembl chr12:56,341,597...56,360,203 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 multiple interactions ISO IL6 protein affects the reaction [Poly I-C results in increased phosphorylation of and results in increased activity of STAT3 protein]; Poly I-C results in increased phosphorylation of and results in increased activity of STAT3 protein CTD PMID:21195166 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G STXBP6 syntaxin binding protein 6 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of STXBP6 mRNA CTD PMID:26923065 NCBI chr14:24,809,454...25,050,147
Ensembl chr14:24,809,454...25,050,147 		JBrowse link
G SVIP small VCP interacting protein multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SVIP mRNA CTD PMID:26923065 NCBI chr11:22,818,927...22,829,801
Ensembl chr11:22,813,799...22,830,299 		JBrowse link
G SYT11 synaptotagmin 11 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SYT11 mRNA CTD PMID:26923065 NCBI chr 1:155,859,567...155,885,199
Ensembl chr 1:155,859,567...155,885,199 		JBrowse link
G TBC1D9 TBC1 domain family member 9 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of TBC1D9 mRNA CTD PMID:26923065 NCBI chr 4:140,620,782...140,756,385
Ensembl chr 4:140,620,782...140,756,385 		JBrowse link
G TBK1 TANK binding kinase 1 increases phosphorylation
multiple interactions		 ISO Poly I-C results in increased phosphorylation of TBK1 protein
APPL1 protein promotes the reaction [Poly I-C results in increased phosphorylation of TBK1 protein]; bafilomycin A1 promotes the reaction [Poly I-C results in increased phosphorylation of TBK1 protein]		 CTD PMID:25780039 NCBI chr12:64,452,120...64,502,114
Ensembl chr12:64,452,090...64,502,114 		JBrowse link
G TFB1M transcription factor B1, mitochondrial multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of TFB1M mRNA CTD PMID:26923065 NCBI chr 6:155,229,871...155,314,484
Ensembl chr 6:155,256,134...155,314,493 		JBrowse link
G TGFB1 transforming growth factor beta 1 increases secretion EXP Poly I-C results in increased secretion of TGFB1 protein CTD PMID:34740670 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G THY1 Thy-1 cell surface antigen multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of THY1 mRNA CTD PMID:26923065 NCBI chr11:119,415,476...119,424,985
Ensembl chr11:119,415,476...119,424,985 		JBrowse link
G TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 affects localization EXP Poly I-C affects the localization of TIAL1 protein CTD PMID:22240577 NCBI chr10:119,573,465...119,596,964
Ensembl chr10:119,571,802...119,597,029 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 increases expression EXP Poly I-C results in increased expression of TICAM1 mRNA CTD PMID:21418039 NCBI chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 increases expression ISO Poly I-C results in increased expression of TIMP1 mRNA CTD PMID:21195166 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
G TLR2 toll like receptor 2 increases expression EXP Poly I-C results in increased expression of TLR2 mRNA CTD PMID:17669408 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260 		JBrowse link
G TLR3 toll like receptor 3 multiple interactions
increases activity
increases expression		 EXP
ISO		 [[Poly I-C binds to and results in increased activity of TLR3 protein] which co-treated with Nanotubes, Carbon] results in increased secretion of IL12B protein; [[Poly I-C binds to and results in increased activity of TLR3 protein] which co-treated with Nanotubes, Carbon] results in increased secretion of TNF protein; [Poly I-C binds to TLR3 protein] which affects the susceptibility to 1-aminopyrene; [Poly I-C binds to TLR3 protein] which affects the susceptibility to 1-nitropyrene; [Poly I-C binds to TLR3 protein] which affects the susceptibility to pyrene; [Vehicle Emissions analog co-treated with Poly I-C] results in increased expression of TLR3 mRNA; [Vehicle Emissions analog co-treated with Poly I-C] results in increased expression of TLR3 protein; Chloroquine inhibits the reaction [Poly I-C results in increased activity of TLR3 protein]; Poly I-C binds to and results in increased activity of TLR3 protein; Quinacrine inhibits the reaction [Poly I-C results in increased activity of TLR3 protein]; TLR3 mRNA promotes the reaction [Poly I-C results in increased expression of IL6 mRNA]; TLR3 mRNA promotes the reaction [Poly I-C results in increased expression of SERPINE1 mRNA]; TLR3 protein affects the reaction [Poly I-C results in increased expression of CXCL8 mRNA]; TLR3 protein affects the reaction [Poly I-C results in increased expression of IFNB1 mRNA]
MIR26A mRNA inhibits the reaction [Poly I-C results in increased activity of TLR3 protein]
Poly I-C results in increased expression of TLR3 mRNA
cinnamaldehyde inhibits the reaction [Poly I-C results in increased expression of TLR3 mRNA]		 CTD PMID:16399790 PMID:17669408 PMID:18306459 PMID:18779317 PMID:21398612 More... NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,068,911...186,088,073 		JBrowse link
G TLR7 toll like receptor 7 increases expression EXP Poly I-C results in increased expression of TLR7 mRNA CTD PMID:17669408 NCBI chr  X:12,867,072...12,890,361
Ensembl chr  X:12,867,072...12,890,361 		JBrowse link
G TMEM266 transmembrane protein 266 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of TMEM266 mRNA CTD PMID:26923065 NCBI chr15:76,059,985...76,204,963
Ensembl chr15:76,059,958...76,229,121 		JBrowse link
G TMEM273 transmembrane protein 273 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of TMEM273 mRNA CTD PMID:26923065 NCBI chr10:49,154,736...49,188,391
Ensembl chr10:49,154,725...49,188,585 		JBrowse link
G TMPRSS2 transmembrane serine protease 2 decreases response to substance ISO TMPRSS2 gene mutant form results in decreased susceptibility to Poly I-C CTD PMID:30626688 NCBI chr21:41,529,791...41,531,118
Ensembl chr21:41,464,300...41,531,116 		JBrowse link
G TMX1 thioredoxin related transmembrane protein 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of TMX1 mRNA CTD PMID:26923065 NCBI chr14:51,240,247...51,257,655
Ensembl chr14:51,240,162...51,257,655 		JBrowse link
G TNF tumor necrosis factor increases secretion
increases expression
multiple interactions		 EXP
ISO		 Poly I-C results in increased secretion of TNF protein
Poly I-C results in increased expression of TNF mRNA; Poly I-C results in increased expression of TNF protein
cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester inhibits the reaction [Poly I-C results in increased expression of TNF mRNA]; MIR26A mRNA inhibits the reaction [Poly I-C results in increased expression of TNF mRNA]; MIR26A mRNA inhibits the reaction [Poly I-C results in increased expression of TNF protein]
APPL1 protein inhibits the reaction [Poly I-C results in increased expression of TNF protein]; Citrinin inhibits the reaction [Poly I-C results in increased expression of TNF mRNA]; Citrinin inhibits the reaction [Poly I-C results in increased expression of TNF protein]; Cycloheximide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; Dimethyl Sulfoxide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; Ethanol inhibits the reaction [Poly I-C results in increased expression of TNF mRNA]; Ethanol inhibits the reaction [Poly I-C results in increased expression of TNF protein]; Ethanol inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; Ethanol promotes the reaction [Hydroxamic Acids analog promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]]]; Hydroxamic Acids analog inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; Hydroxamic Acids analog promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]]; Luteolin inhibits the reaction [Poly I-C results in increased expression of TNF mRNA]; Poly I-C promotes the reaction [deoxynivalenol results in increased expression of TNF mRNA]; sodium arsenite inhibits the reaction [Poly I-C results in increased expression of TNF mRNA]
2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane promotes the reaction [Poly I-C results in increased expression of TNF protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; 4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol promotes the reaction [Poly I-C results in increased expression of TNF protein]; [[Poly I-C binds to and results in increased activity of TLR3 protein] which co-treated with Nanotubes, Carbon] results in increased secretion of TNF protein; CEP-11004 inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; CpG ODN 2006 inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; Estradiol promotes the reaction [Poly I-C results in increased expression of TNF protein]; N-(3,5-bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; pyrazolanthrone inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; RTKI cpd inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; SB 203580 inhibits the reaction [Poly I-C results in increased secretion of TNF protein]		 CTD PMID:16687389 PMID:17238832 PMID:17321468 PMID:17669408 PMID:17698565 More... NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFSF10 TNF superfamily member 10 increases expression ISO Poly I-C results in increased expression of TNFSF10 mRNA; Poly I-C results in increased expression of TNFSF10 protein CTD PMID:16472598 NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475 		JBrowse link
G TNKS2 tankyrase 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of TNKS2 mRNA CTD PMID:26923065 NCBI chr10:91,798,426...91,865,475
Ensembl chr10:91,798,426...91,865,475 		JBrowse link
G TP53 tumor protein p53 multiple interactions EXP TP53 protein affects the reaction [Poly I-C affects the localization of RELA protein]; TP53 protein affects the reaction [Poly I-C results in increased expression of CXCL8 mRNA]; TP53 protein affects the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; TP53 protein affects the reaction [Poly I-C results in increased phosphorylation of IRF3 protein]; TP53 protein affects the reaction [Poly I-C results in increased phosphorylation of NFKBIA protein]; TP53 results in increased susceptibility to [Poly I-C co-treated with Fluorouracil] CTD PMID:18779317 PMID:20367642 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538 		JBrowse link
G TPD52 tumor protein D52 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of TPD52 mRNA CTD PMID:26923065 NCBI chr 8:80,031,082...80,171,564
Ensembl chr 8:80,034,745...80,231,232 		JBrowse link
G TPK1 thiamin pyrophosphokinase 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of TERF2IP mRNA CTD PMID:26923065 NCBI chr 7:144,451,941...144,836,437
Ensembl chr 7:144,451,941...144,836,395 		JBrowse link
G TRAF6 TNF receptor associated factor 6 multiple interactions EXP TRAF6 mutant form inhibits the reaction [Vehicle Emissions analog promotes the reaction [Poly I-C results in increased expression of IL6 mRNA]] CTD PMID:16399790 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G TRIM2 tripartite motif containing 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of TRIM2 mRNA CTD PMID:26923065 NCBI chr 4:153,152,163...153,339,317
Ensembl chr 4:153,152,163...153,339,319 		JBrowse link
G TSLP thymic stromal lymphopoietin multiple interactions
increases expression		 EXP 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; 4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol promotes the reaction [Poly I-C results in increased expression of TSLP protein]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; [Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA; [Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; Estradiol promotes the reaction [Poly I-C results in increased expression of TSLP protein]; helenalin inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; helenalin inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; IL4 protein promotes the reaction [Poly I-C results in increased expression of TSLP mRNA]; IL4 protein promotes the reaction [Poly I-C results in increased expression of TSLP protein]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]
Poly I-C results in increased expression of TSLP mRNA; Poly I-C results in increased expression of TSLP protein		 CTD PMID:23688403 PMID:30017638 NCBI chr 5:111,070,062...111,078,026
Ensembl chr 5:111,070,062...111,078,026 		JBrowse link
G TSPYL5 TSPY like 5 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of TSPYL5 mRNA CTD PMID:26923065 NCBI chr 8:97,273,488...97,277,928
Ensembl chr 8:97,273,488...97,277,928 		JBrowse link
G TTC3 tetratricopeptide repeat domain 3 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of TTC3 mRNA CTD PMID:26923065 NCBI chr21:37,073,254...37,203,118
Ensembl chr21:37,073,226...37,203,112 		JBrowse link
G TWIST1 twist family bHLH transcription factor 1 decreases expression ISO Poly I-C results in decreased expression of TWIST1 mRNA CTD PMID:26923065 NCBI chr 7:19,113,047...19,117,636
Ensembl chr 7:19,020,991...19,117,636 		JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of TWSG1 mRNA CTD PMID:26923065 NCBI chr18:9,334,773...9,402,420
Ensembl chr18:9,334,767...9,402,420 		JBrowse link
G TXN thioredoxin multiple interactions
increases expression		 ISO Diclofenac inhibits the reaction [Poly I-C results in increased expression of TXN1 mRNA] CTD PMID:23939143 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507 		JBrowse link
G UBL4A ubiquitin like 4A multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of UBL4A mRNA CTD PMID:26923065 NCBI chr  X:154,483,717...154,486,615
Ensembl chr  X:154,483,717...154,486,615 		JBrowse link
G UBR1 ubiquitin protein ligase E3 component n-recognin 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of UBR1 mRNA CTD PMID:26923065 NCBI chr15:42,942,897...43,106,038
Ensembl chr15:42,942,897...43,106,113 		JBrowse link
G UGT2B17 UDP glucuronosyltransferase family 2 member B17 decreases expression ISO Poly I-C results in decreased expression of UGT2B1 mRNA CTD PMID:23939143 NCBI chr 4:68,537,173...68,576,322
Ensembl chr 4:68,537,173...68,576,413 		JBrowse link
G USP32 ubiquitin specific peptidase 32 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of USP32 mRNA CTD PMID:26923065 NCBI chr17:60,177,327...60,422,416
Ensembl chr17:60,177,327...60,422,470 		JBrowse link
G VSNL1 visinin like 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of VSNL1 mRNA CTD PMID:26923065 NCBI chr 2:17,539,972...17,657,018
Ensembl chr 2:17,539,126...17,657,018 		JBrowse link
G WAC WW domain containing adaptor with coiled-coil multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of WAC mRNA CTD PMID:26923065 NCBI chr10:28,532,779...28,623,112
Ensembl chr10:28,532,493...28,623,112 		JBrowse link
G WDR47 WD repeat domain 47 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of WDR47 mRNA CTD PMID:26923065 NCBI chr 1:108,970,214...109,042,102
Ensembl chr 1:108,970,214...109,042,113 		JBrowse link
G ZBTB6 zinc finger and BTB domain containing 6 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ZBTB6 mRNA CTD PMID:26923065 NCBI chr 9:122,908,056...122,913,323
Ensembl chr 9:122,908,056...122,913,323 		JBrowse link
G ZDHHC21 zinc finger DHHC-type palmitoyltransferase 21 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ZDHHC21 mRNA CTD PMID:26923065 NCBI chr 9:14,588,797...14,693,432
Ensembl chr 9:14,611,071...14,693,432 		JBrowse link
G ZNF354C zinc finger protein 354C multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ZFP354C mRNA CTD PMID:26923065 NCBI chr 5:179,060,373...179,083,977
Ensembl chr 5:179,060,373...179,083,977 		JBrowse link
G ZNF487 zinc finger protein 487 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ZFP763 mRNA CTD PMID:26923065 NCBI chr10:43,436,848...43,523,894
Ensembl chr10:43,436,841...43,483,181 		JBrowse link
SAICAR term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PKM pyruvate kinase M1/2 multiple interactions EXP Glucose deficiency promotes the reaction [SAICAR binds to and results in increased activity of PKM protein] CTD PMID:23086999 NCBI chr15:72,199,029...72,231,591
Ensembl chr15:72,199,029...72,231,819 		JBrowse link
sofosbuvir term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KLRC1 killer cell lectin like receptor C1 decreases expression EXP sofosbuvir co-treated with ledipasvir decreases expression of NCR1 protein in natural killer cells RGD PMID:31218578 RGD:40400920 NCBI chr12:10,442,264...10,454,685
Ensembl chr12:10,442,264...10,454,685 		JBrowse link
G NCR1 natural cytotoxicity triggering receptor 1 affects expression EXP sofosbuvir co-treated with ledipasvir affects expression of NCR1 protein in natural killer cells RGD PMID:31218578 RGD:40400920 NCBI chr19:54,898,198...54,938,208
Ensembl chr19:54,906,148...54,916,140 		JBrowse link
stearoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSTA1 glutathione S-transferase alpha 1 multiple interactions EXP stearoyl-coenzyme A binds to and results in decreased activity of GSTA1 protein CTD PMID:10542059 NCBI chr 6:52,791,371...52,803,816
Ensembl chr 6:52,791,371...52,803,860 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions EXP stearoyl-coenzyme A binds to and results in increased activity of PPARA protein CTD PMID:11139385 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions EXP stearoyl-coenzyme A binds to and results in increased activity of PPARG protein CTD PMID:11139385 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
succinyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOT4 acyl-CoA thioesterase 4 affects hydrolysis ISO ACOT4 protein affects the hydrolysis of succinyl-coenzyme A CTD PMID:16141203 NCBI chr14:73,591,873...73,595,766
Ensembl chr14:73,591,873...73,595,766 		JBrowse link
TNP-ATP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2RX1 purinergic receptor P2X 1 affects binding ISO TNP-ATP binds to P2rx1 protein RGD PMID:12237343 RGD:727431 NCBI chr17:3,896,592...3,916,465
Ensembl chr17:3,896,592...3,916,476 		JBrowse link
G P2RX2 purinergic receptor P2X 2 multiple interactions ISO TNP-ATP binds to P2rx2 protein; TNP-ATP inhibits the reaction [ATP binds to P2rx2 protein] in transfected glial cells RGD PMID:16388598 RGD:1642662 NCBI chr12:132,618,776...132,622,388
Ensembl chr12:132,618,776...132,622,388 		JBrowse link
G P2RX5 purinergic receptor P2X 5 affects transport ISO TNP-ATP affects transport ion flux of P2rx5 receptor RGD PMID:12237343 RGD:727431 NCBI chr17:3,673,227...3,696,155
Ensembl chr17:3,672,199...3,696,240 		JBrowse link
UDP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCL2 C-X-C motif chemokine ligand 2 multiple interactions ISO P2RY6 gene affects the reaction [Uridine Diphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of CXCL2 protein]]; Uridine Diphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of CXCL2 protein] CTD PMID:18523137 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP [Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased expression of CXCL8 protein; montelukast inhibits the reaction [[Uridine Diphosphate metabolite results in increased activity of CYSLTR1 protein] which results in increased expression of CXCL8 protein]; zafirlukast inhibits the reaction [[Uridine Diphosphate metabolite results in increased activity of CYSLTR1 protein] which results in increased expression of CXCL8 protein] CTD PMID:20083671 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 multiple interactions EXP [Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased expression of CXCL8 protein; montelukast inhibits the reaction [[Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; montelukast inhibits the reaction [[Uridine Diphosphate metabolite results in increased activity of CYSLTR1 protein] which results in increased expression of CXCL8 protein]; Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein; zafirlukast inhibits the reaction [[Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; zafirlukast inhibits the reaction [[Uridine Diphosphate metabolite results in increased activity of CYSLTR1 protein] which results in increased expression of CXCL8 protein] CTD PMID:20083671 NCBI chr  X:78,271,468...78,327,611
Ensembl chr  X:78,271,468...78,327,691 		JBrowse link
G GPR17 G protein-coupled receptor 17 multiple interactions ISO cangrelor inhibits the reaction [Uridine Diphosphate results in increased activity of GPR17 protein] CTD PMID:18974869 NCBI chr 2:127,646,153...127,652,639
Ensembl chr 2:127,645,864...127,652,639 		JBrowse link
G H2AX H2A.X variant histone multiple interactions EXP Uridine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form] CTD PMID:32941855 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465 		JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
increases abundance		 ISO Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Uridine Diphosphate] CTD PMID:27469509 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477 		JBrowse link
G IL6 interleukin 6 multiple interactions
increases expression		 ISO MRS 2211 inhibits the reaction [Uridine Diphosphate results in increased expression of IL6 protein]; P2RY6 gene affects the reaction [Uridine Diphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; Uridine Diphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:18523137 PMID:24849676 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 increases phosphorylation
multiple interactions		 EXP
ISO		 Uridine Diphosphate results in increased phosphorylation of MAPK1 protein
P2RY6 gene mutant form inhibits the reaction [Uridine Diphosphate results in increased phosphorylation of MAPK1 protein]		 CTD PMID:15034929 PMID:18523137 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 increases phosphorylation
multiple interactions		 EXP
ISO		 Uridine Diphosphate results in increased phosphorylation of MAPK3 protein
P2RY6 gene mutant form inhibits the reaction [Uridine Diphosphate results in increased phosphorylation of MAPK3 protein]		 CTD PMID:15034929 PMID:18523137 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G P2RY6 pyrimidinergic receptor P2Y6 multiple interactions
affects response to substance		 ISO P2RY6 gene affects the reaction [Uridine Diphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of CXCL2 protein]]; P2RY6 gene affects the reaction [Uridine Diphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; P2RY6 gene mutant form inhibits the reaction [Uridine Diphosphate results in increased phosphorylation of MAPK1 protein]; P2RY6 gene mutant form inhibits the reaction [Uridine Diphosphate results in increased phosphorylation of MAPK3 protein]
P2RY6 gene affects the susceptibility to Uridine Diphosphate		 CTD PMID:18523137 NCBI chr11:73,264,506...73,298,625
Ensembl chr11:73,264,498...73,305,103 		JBrowse link
G TP53BP1 tumor protein p53 binding protein 1 multiple interactions EXP Uridine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein] CTD PMID:32941855 NCBI chr15:43,403,061...43,510,640
Ensembl chr15:43,403,061...43,510,728 		JBrowse link
UDP-alpha-D-galactose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GALE UDP-galactose-4-epimerase affects binding EXP Uridine Diphosphate Galactose binds to GALE protein CTD PMID:25526675 NCBI chr 1:23,795,599...23,800,754
Ensembl chr 1:23,795,599...23,800,781 		JBrowse link
G GPR17 G protein-coupled receptor 17 increases activity ISO Uridine Diphosphate Galactose results in increased activity of GPR17 protein CTD PMID:18974869 NCBI chr 2:127,646,153...127,652,639
Ensembl chr 2:127,645,864...127,652,639 		JBrowse link
G UXS1 UDP-glucuronate decarboxylase 1 multiple interactions EXP [Uridine Diphosphate Galactose co-treated with NAD] binds to UXS1 protein CTD PMID:25526675 NCBI chr 2:106,093,311...106,194,301
Ensembl chr 2:106,093,308...106,194,301 		JBrowse link
UDP-alpha-D-glucose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GALE UDP-galactose-4-epimerase affects binding EXP Uridine Diphosphate Glucose binds to GALE protein CTD PMID:25526675 NCBI chr 1:23,795,599...23,800,754
Ensembl chr 1:23,795,599...23,800,781 		JBrowse link
G GPR17 G protein-coupled receptor 17 increases activity ISO Uridine Diphosphate Glucose results in increased activity of GPR17 protein CTD PMID:18974869 NCBI chr 2:127,646,153...127,652,639
Ensembl chr 2:127,645,864...127,652,639 		JBrowse link
G UXS1 UDP-glucuronate decarboxylase 1 multiple interactions EXP [Uridine Diphosphate Glucose co-treated with NAD] binds to UXS1 protein CTD PMID:25526675 NCBI chr 2:106,093,311...106,194,301
Ensembl chr 2:106,093,308...106,194,301 		JBrowse link
UDP-alpha-D-glucuronic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB11 ATP binding cassette subfamily B member 11 multiple interactions EXP [NADP co-treated with Uridine Diphosphate Glucuronic Acid co-treated with Phosphoadenosine Phosphosulfate] promotes the reaction [[Enzymes and Coenzymes results in increased metabolism of diosbulbin B] inhibits the reaction [ABCB11 protein results in increased transport of Taurodeoxycholic Acid]]; [NADP co-treated with Uridine Diphosphate Glucuronic Acid co-treated with Phosphoadenosine Phosphosulfate] promotes the reaction [[Enzymes and Coenzymes results in increased metabolism of saikogenin A analog] inhibits the reaction [ABCB11 protein results in increased transport of Taurodeoxycholic Acid]]; [NADP co-treated with Uridine Diphosphate Glucuronic Acid co-treated with Phosphoadenosine Phosphosulfate] promotes the reaction [[Enzymes and Coenzymes results in increased metabolism of saikogenin A] inhibits the reaction [ABCB11 protein results in increased transport of Taurodeoxycholic Acid]] CTD PMID:35101544 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324 		JBrowse link
G B3GAT3 beta-1,3-glucuronyltransferase 3 affects binding
multiple interactions		 EXP B3GAT3 protein binds to Uridine Diphosphate Glucuronic Acid
Uridine Diphosphate Glucuronic Acid inhibits the reaction [Diacetyl results in decreased activity of B3GAT3 protein]		 CTD PMID:11986319 NCBI chr11:62,615,296...62,621,986
Ensembl chr11:62,615,296...62,622,154 		JBrowse link
G GALE UDP-galactose-4-epimerase affects binding EXP Uridine Diphosphate Glucuronic Acid binds to GALE protein CTD PMID:25526675 NCBI chr 1:23,795,599...23,800,754
Ensembl chr 1:23,795,599...23,800,781 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha increases expression EXP Uridine Diphosphate Glucuronic Acid results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 multiple interactions EXP [Uridine Diphosphate Glucuronic Acid co-treated with UGT1A1 protein] results in increased glucuronidation of Labetalol CTD PMID:18098064 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300 		JBrowse link
G UGT1A3 UDP glucuronosyltransferase family 1 member A3 multiple interactions EXP [Uridine Diphosphate Glucuronic Acid co-treated with UGT1A3 protein] results in increased metabolism of Lithocholic Acid CTD PMID:36473578 NCBI chr 2:233,729,042...233,773,300
Ensembl chr 2:233,729,042...233,773,300 		JBrowse link
G UGT2B7 UDP glucuronosyltransferase family 2 member B7 multiple interactions EXP [Uridine Diphosphate Glucuronic Acid co-treated with UGT2B7 protein] results in increased glucuronidation of Labetalol; [Uridine Diphosphate Glucuronic Acid co-treated with UGT2B7 protein] results in increased metabolism of hyodeoxycholic acid; Fluconazole inhibits the reaction [[Uridine Diphosphate Glucuronic Acid co-treated with UGT2B7 protein] results in increased glucuronidation of Labetalol] CTD PMID:18098064 PMID:36473578 NCBI chr 4:69,051,375...69,112,987
Ensembl chr 4:69,051,363...69,112,987 		JBrowse link
G UXS1 UDP-glucuronate decarboxylase 1 multiple interactions EXP [Uridine Diphosphate Glucuronic Acid co-treated with NAD] binds to UXS1 protein CTD PMID:25526675 NCBI chr 2:106,093,311...106,194,301
Ensembl chr 2:106,093,308...106,194,301 		JBrowse link
UDP-D-galactose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GALE UDP-galactose-4-epimerase affects binding EXP Uridine Diphosphate Galactose binds to GALE protein CTD PMID:25526675 NCBI chr 1:23,795,599...23,800,754
Ensembl chr 1:23,795,599...23,800,781 		JBrowse link
G GPR17 G protein-coupled receptor 17 increases activity ISO Uridine Diphosphate Galactose results in increased activity of GPR17 protein CTD PMID:18974869 NCBI chr 2:127,646,153...127,652,639
Ensembl chr 2:127,645,864...127,652,639 		JBrowse link
G UXS1 UDP-glucuronate decarboxylase 1 multiple interactions EXP [Uridine Diphosphate Galactose co-treated with NAD] binds to UXS1 protein CTD PMID:25526675 NCBI chr 2:106,093,311...106,194,301
Ensembl chr 2:106,093,308...106,194,301 		JBrowse link
UDP-D-glucose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GALE UDP-galactose-4-epimerase affects binding EXP Uridine Diphosphate Glucose binds to GALE protein CTD PMID:25526675 NCBI chr 1:23,795,599...23,800,754
Ensembl chr 1:23,795,599...23,800,781 		JBrowse link
G GPR17 G protein-coupled receptor 17 increases activity ISO Uridine Diphosphate Glucose results in increased activity of GPR17 protein CTD PMID:18974869 NCBI chr 2:127,646,153...127,652,639
Ensembl chr 2:127,645,864...127,652,639 		JBrowse link
G UXS1 UDP-glucuronate decarboxylase 1 multiple interactions EXP [Uridine Diphosphate Glucose co-treated with NAD] binds to UXS1 protein CTD PMID:25526675 NCBI chr 2:106,093,311...106,194,301
Ensembl chr 2:106,093,308...106,194,301 		JBrowse link
UDP-N-acetyl-alpha-D-galactosamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GALE UDP-galactose-4-epimerase affects binding EXP Uridine Diphosphate N-Acetylgalactosamine binds to GALE protein CTD PMID:25526675 NCBI chr 1:23,795,599...23,800,754
Ensembl chr 1:23,795,599...23,800,781 		JBrowse link
UDP-N-acetyl-alpha-D-glucosamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 increases abundance
multiple interactions		 ISO IDH2 protein mutant form results in increased abundance of Uridine Diphosphate N-Acetylglucosamine
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Uridine Diphosphate N-Acetylglucosamine]		 CTD PMID:27469509 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477 		JBrowse link
uridine 5'-monophosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BSG basigin (Ok blood group) decreases expression EXP Uridine Monophosphate results in decreased expression of BSG protein CTD PMID:36574092 NCBI chr19:571,283...583,493
Ensembl chr19:571,277...583,494 		JBrowse link
UTP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor multiple interactions ISO Uridine Triphosphate affects the folding of [Tetrachlorodibenzodioxin binds to AHR protein] CTD PMID:1848756 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G CALCA calcitonin related polypeptide alpha multiple interactions ISO Uridine Triphosphate promotes the reaction [Protons results in increased secretion of CALCA protein] CTD PMID:12044622 NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354 		JBrowse link
G EGFR epidermal growth factor receptor increases phosphorylation ISO Uridine Triphosphate results in increased phosphorylation of EGFR protein CTD PMID:14676212 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G GNAQ G protein subunit alpha q multiple interactions ISO Uridine Triphosphate inhibits the reaction [GNAQ protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]] CTD PMID:14676212 NCBI chr 9:77,716,097...78,031,811
Ensembl chr 9:77,716,097...78,031,811 		JBrowse link
G H2AX H2A.X variant histone multiple interactions EXP Uridine Triphosphate inhibits the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form] CTD PMID:32941855 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465 		JBrowse link
G HCAR2 hydroxycarboxylic acid receptor 2 multiple interactions EXP [Nicotinic Acids results in increased activity of HCAR2 protein] promotes the reaction [[Uridine Triphosphate results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased abundance of Arachidonic Acids]; [Nicotinic Acids results in increased activity of HCAR2 protein] promotes the reaction [[Uridine Triphosphate results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased abundance of Arachidonic Acids] CTD PMID:16674924 NCBI chr12:122,701,293...122,703,357
Ensembl chr12:122,701,293...122,703,357 		JBrowse link
G IL6 interleukin 6 multiple interactions
increases expression		 EXP
ISO		 NF157 compound inhibits the reaction [Uridine Triphosphate results in increased expression of IL6 protein]; Suramin inhibits the reaction [Uridine Triphosphate results in increased expression of IL6 protein]
MRS 2211 inhibits the reaction [Uridine Triphosphate results in increased expression of IL6 protein]		 CTD PMID:24793913 PMID:24849676 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation		 EXP
ISO		 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Uridine Triphosphate results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased abundance of Arachidonic Acids]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Uridine Triphosphate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; [Nicotinic Acids results in increased activity of HCAR2 protein] promotes the reaction [[Uridine Triphosphate results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased abundance of Arachidonic Acids]; [Uridine Triphosphate results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased abundance of Arachidonic Acids; Uridine Triphosphate results in increased phosphorylation of and results in increased activity of MAPK1 protein
RTKI cpd inhibits the reaction [Uridine Triphosphate results in increased phosphorylation of and results in increased activity of MAPK1 protein]
Uridine Triphosphate results in increased phosphorylation of MAPK1 protein		 CTD PMID:14676212 PMID:15034929 PMID:16674924 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation		 EXP
ISO		 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Uridine Triphosphate results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased abundance of Arachidonic Acids]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Uridine Triphosphate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; [Nicotinic Acids results in increased activity of HCAR2 protein] promotes the reaction [[Uridine Triphosphate results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased abundance of Arachidonic Acids]; [Uridine Triphosphate results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased abundance of Arachidonic Acids; Uridine Triphosphate results in increased phosphorylation of and results in increased activity of MAPK3 protein
RTKI cpd inhibits the reaction [Uridine Triphosphate results in increased phosphorylation of and results in increased activity of MAPK3 protein]
Uridine Triphosphate results in increased phosphorylation of MAPK3 protein		 CTD PMID:14676212 PMID:15034929 PMID:16674924 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MYL2 myosin light chain 2 multiple interactions ISO Uridine Triphosphate inhibits the reaction [MYL2 protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]]; Uridine Triphosphate inhibits the reaction [MYOCD protein results in increased expression of MYL2 protein] CTD PMID:14676212 NCBI chr12:110,910,845...110,921,449
Ensembl chr12:110,910,819...110,921,443 		JBrowse link
G MYOCD myocardin multiple interactions ISO Uridine Triphosphate inhibits the reaction [MYOCD protein results in increased expression of MYL2 protein]; Uridine Triphosphate inhibits the reaction [MYOCD protein results in increased expression of NPPA protein] CTD PMID:14676212 NCBI chr17:12,665,890...12,768,949
Ensembl chr17:12,665,890...12,768,949 		JBrowse link
G NPPA natriuretic peptide A multiple interactions
increases expression		 ISO Uridine Triphosphate inhibits the reaction [GNAQ protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]]; Uridine Triphosphate inhibits the reaction [MYL2 protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]]; Uridine Triphosphate inhibits the reaction [MYOCD protein results in increased expression of NPPA protein]; Uridine Triphosphate inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]
Uridine Triphosphate results in increased expression of NPPA mRNA		 CTD PMID:14676212 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345 		JBrowse link
G P2RX1 purinergic receptor P2X 1 affects binding ISO UTP binds to P2rx1 protein RGD PMID:12237343 RGD:727431 NCBI chr17:3,896,592...3,916,465
Ensembl chr17:3,896,592...3,916,476 		JBrowse link
G P2RY2 purinergic receptor P2Y2 multiple interactions ISO
EXP		 Uridine Triphosphate binds to and results in increased activity of P2RY2 protein
Endocannabinoids inhibits the reaction [Uridine Triphosphate binds to and results in increased activity of P2RY2 protein]; Uridine Triphosphate binds to and results in increased activity of P2RY2 protein		 CTD PMID:15654852 PMID:30102254 NCBI chr11:73,218,281...73,242,427
Ensembl chr11:73,218,281...73,242,427 		JBrowse link
G P2RY4 pyrimidinergic receptor P2Y4 multiple interactions ISO Uridine Triphosphate binds to and results in increased activity of P2RY4 protein CTD PMID:15654852 NCBI chr  X:70,258,166...70,260,204
Ensembl chr  X:70,258,166...70,260,204 		JBrowse link
G PANX1 pannexin 1 decreases activity ISO Uridine Triphosphate results in decreased activity of PANX1 protein CTD PMID:19023039 NCBI chr11:94,128,841...94,181,968
Ensembl chr11:94,128,841...94,181,968 		JBrowse link
G SFTPB surfactant protein B increases secretion ISO Uridine Triphosphate results in increased secretion of SFTPB protein CTD PMID:14565945 NCBI chr 2:85,657,307...85,668,741
Ensembl chr 2:85,657,314...85,668,741 		JBrowse link
G SFTPC surfactant protein C increases secretion ISO Uridine Triphosphate results in increased secretion of SFTPC protein CTD PMID:14565945 NCBI chr 8:22,157,383...22,164,479
Ensembl chr 8:22,156,913...22,164,479 		JBrowse link
G TP53BP1 tumor protein p53 binding protein 1 multiple interactions EXP Uridine Triphosphate inhibits the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein] CTD PMID:32941855 NCBI chr15:43,403,061...43,510,640
Ensembl chr15:43,403,061...43,510,728 		JBrowse link
G TRPC3 transient receptor potential cation channel subfamily C member 3 increases activity
multiple interactions		 ISO Uridine Triphosphate results in increased activity of TRPC3 protein
ethyl-1-(4-(2*3*3-trichloroacrylamide)phenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate inhibits the reaction [Uridine Triphosphate results in increased activity of TRPC3 protein]		 CTD PMID:19289841 NCBI chr 4:121,874,481...121,952,060
Ensembl chr 4:121,874,481...121,952,060 		JBrowse link
G TRPC5 transient receptor potential cation channel subfamily C member 5 increases activity ISO Uridine Triphosphate results in increased activity of TRPC5 protein CTD PMID:19289841 NCBI chr  X:111,768,011...112,082,776
Ensembl chr  X:111,768,011...112,082,776 		JBrowse link
G TRPC6 transient receptor potential cation channel subfamily C member 6 increases activity ISO Uridine Triphosphate results in increased activity of TRPC6 protein CTD PMID:19289841 NCBI chr11:101,451,564...101,584,007
Ensembl chr11:101,451,564...101,872,562 		JBrowse link
G TRPC7 transient receptor potential cation channel subfamily C member 7 increases activity ISO Uridine Triphosphate results in increased activity of TRPC7 protein CTD PMID:19289841 NCBI chr 5:136,212,745...136,365,545
Ensembl chr 5:136,212,745...136,365,545 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26034
    role 25961
      application 25172
        NMR chemical shift reference compound 20287
          phosphoric acid 11872
            phosphoric acid derivative 11674
              organic phosphate 11673
                carbohydrate phosphate 1897
                  phospho sugar 1742
                    aldose phosphate 1739
                      aldopentose phosphate 1731
                        ribose phosphate 1724
                          1-(phosphoribosyl)imidazole + 111
                          phosphomethylribose + 0
                          ribonucleotide + 1683
                          ribose bisphosphate + 0
                          ribose diphosphate + 0
                          ribose monophosphate + 1
                          ribose triphosphate + 0
                          thioribose phosphate + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 26034
    subatomic particle 26009
      composite particle 26009
        hadron 26020
          baryon 26009
            nucleon 26009
              atomic nucleus 26009
                atom 26009
                  main group element atom 25834
                    p-block element atom 25834
                      chalcogen 24917
                        oxygen atom 24817
                          oxygen molecular entity 24806
                            hydroxides 24049
                              oxoacid 22975
                                pnictogen oxoacid 13799
                                  phosphorus oxoacid 12848
                                    phosphoric acids 11880
                                      phosphoric acid 11872
                                        phosphoric acid derivative 11674
                                          phosphate 11673
                                            organic phosphate 11673
                                              carbohydrate phosphate 1897
                                                phospho sugar 1742
                                                  aldose phosphate 1739
                                                    aldopentose phosphate 1731
                                                      ribose phosphate 1724
                                                        1-(phosphoribosyl)imidazole + 111
                                                        phosphomethylribose + 0
                                                        ribonucleotide + 1683
                                                        ribose bisphosphate + 0
                                                        ribose diphosphate + 0
                                                        ribose monophosphate + 1
                                                        ribose triphosphate + 0
                                                        thioribose phosphate + 0
paths to the root