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ONTOLOGY REPORT - ANNOTATIONS


Term:aminoglutethimide
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Accession:CHEBI:2654 term browser browse the term
Definition:A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.
Synonyms:exact_synonym: 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione
 related_synonym: 2-(p-Aminophenyl)-2-ethylglutarimide;   3-Ethyl-3-(p-aminophenyl)-2,6-dioxopiperidine;   DL-Aminoglutethimide;   Formula=C13H16N2O2;   InChI=1S/C13H16N2O2/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9/h3-6H,2,7-8,14H2,1H3,(H,15,16,17);   InChIKey=ROBVIMPUHSLWNV-UHFFFAOYSA-N;   SMILES=CCC1(CCC(=O)NC1=O)c1ccc(N)cc1;   alpha-(p-Aminophenyl)-alpha-ethylglutarimide;   aminoglutethimidum;   aminoglutetimida;   p-Aminoglutethimide
 xref: Beilstein:210656 "Beilstein";   CAS:125-84-8 "ChemIDplus";   CAS:125-84-8 "DrugBank";   CAS:125-84-8 "KEGG COMPOUND";   CAS:125-84-8 "KEGG DRUG";   CAS:125-84-8 "NIST Chemistry WebBook";   DrugBank:DB00357;   Drug_Central:164 "DrugCentral";   HMDB:HMDB0014501;   KEGG:C07617;   KEGG:D00574;   LINCS:LSM-1409
 xref_mesh: MESH:D000616
 xref: PMID:11916226 "Europe PMC";   PMID:17602675 "Europe PMC";   PMID:24350727 "Europe PMC";   Patent:US2848455;   Reaxys:210656 "Reaxys";   Wikipedia:Aminoglutethimide


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aminoglutethimide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acp1 acid phosphatase 1 JBrowse link 6 49,836,064 49,851,714 RGD:6480464
G Anp32b acidic nuclear phosphoprotein 32 family member B JBrowse link 5 62,070,709 62,094,633 RGD:6480464
G Basp1 brain abundant, membrane attached signal protein 1 JBrowse link 2 77,586,424 77,632,626 RGD:6480464
G Bcap31 B-cell receptor-associated protein 31 JBrowse link X 157,094,365 157,126,397 RGD:6480464
G Cct4 chaperonin containing TCP1 subunit 4 JBrowse link 14 107,767,392 107,780,270 RGD:6480464
G Cct6a chaperonin containing TCP1 subunit 6A JBrowse link 12 30,491,584 30,501,813 RGD:6480464
G Cct7 chaperonin containing TCP1 subunit 7 JBrowse link 4 117,235,023 117,252,265 RGD:6480464
G Comt catechol-O-methyltransferase JBrowse link 11 86,715,981 86,735,630 RGD:6480464
G Cuta cutA divalent cation tolerance homolog JBrowse link 20 5,532,024 5,533,640 RGD:6480464
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 JBrowse link 8 62,798,317 62,809,848 RGD:6480464
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 JBrowse link 1 266,422,127 266,429,947 RGD:6480464
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:6480464
G Fshb follicle stimulating hormone subunit beta JBrowse link 3 98,088,321 98,092,131 RGD:6480464
G Gatd3a glutamine amidotransferase like class 1 domain containing 3A JBrowse link 20 11,244,353 11,252,450 RGD:6480464
G Gns glucosamine (N-acetyl)-6-sulfatase JBrowse link 7 63,467,027 63,501,054 RGD:6480464
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:6480464
G Gsn gelsolin JBrowse link 3 14,456,106 14,508,922 RGD:6480464
G H1f2 H1.2 linker histone, cluster member JBrowse link 17 43,638,938 43,640,445 RGD:6480464
G H2az1 H2A.Z variant histone 1 JBrowse link 2 243,105,224 243,107,333 RGD:6480464
G H2bc12 H2B clustered histone 12 JBrowse link 17 44,527,421 44,527,801 RGD:6480464
G Hmgb2 high mobility group box 2 JBrowse link 16 36,077,615 36,080,191 RGD:6480464
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 JBrowse link 10 35,872,619 35,879,911 RGD:6480464
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 JBrowse link 10 88,987,558 88,989,758 RGD:6480464
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 JBrowse link X 21,696,796 21,699,241 RGD:6480464
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 JBrowse link 18 44,810,462 44,897,677 RGD:6480464
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 JBrowse link 13 88,288,116 88,308,019 RGD:6480464
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:6480464
G Hyou1 hypoxia up-regulated 1 JBrowse link 8 48,699,796 48,711,912 RGD:6480464
G Impdh2 inosine monophosphate dehydrogenase 2 JBrowse link 8 117,346,983 117,351,619 RGD:6480464
G Lhb luteinizing hormone subunit beta JBrowse link 1 101,409,992 101,413,725 RGD:6480464
G Lmna lamin A/C JBrowse link 2 187,842,884 187,863,552 RGD:6480464
G Lmnb2 lamin B2 JBrowse link 7 11,657,870 11,676,936 RGD:6480464
G LOC680322 similar to Histone H2A type 1 JBrowse link 17 44,527,990 44,528,557 RGD:6480464
G LOC684762 similar to CG31613-PA JBrowse link 17 43,776,018 43,776,779 RGD:6480464
G Mcm3 minichromosome maintenance complex component 3 JBrowse link 9 26,914,057 26,932,201 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Myo18a myosin XVIIIa JBrowse link 10 64,979,770 65,080,535 RGD:6480464
G Npm3 nucleophosmin/nucleoplasmin, 3 JBrowse link 1 265,504,105 265,506,080 RGD:6480464
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 11 65,022,100 65,058,546 RGD:6480464
G Nup210 nucleoporin 210 JBrowse link 4 122,643,952 122,741,322 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Pitpnb phosphatidylinositol transfer protein, beta JBrowse link 12 51,279,194 51,341,752 RGD:6480464
G Ppp1ca protein phosphatase 1 catalytic subunit alpha JBrowse link 1 219,439,953 219,443,570 RGD:6480464
G Prdx3 peroxiredoxin 3 JBrowse link 1 282,238,774 282,251,193 RGD:6480464
G Psmb4 proteasome 20S subunit beta 4 JBrowse link 2 196,043,546 196,046,320 RGD:6480464
G Rtraf RNA transcription, translation and transport factor JBrowse link 15 4,882,925 4,893,890 RGD:6480464
G Spp1 secreted phosphoprotein 1 JBrowse link 14 6,673,686 6,679,965 RGD:6480464
G Ssb small RNA binding exonuclease protection factor La JBrowse link 3 56,092,425 56,102,008 RGD:6480464
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:6480464
G Tpt1 tumor protein, translationally-controlled 1 JBrowse link 15 57,891,680 57,894,504 RGD:6480464
G Ubc ubiquitin C JBrowse link 12 36,638,457 36,642,734 RGD:6480464
G Ube2k ubiquitin-conjugating enzyme E2K JBrowse link 14 44,289,247 44,348,691 RGD:6480464
G Wdr1 WD repeat domain 1 JBrowse link 14 76,990,014 77,023,739 RGD:6480464
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta JBrowse link 6 43,463,294 43,493,816 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19657
    role 19601
      application 19225
        pharmaceutical 19089
          drug 19089
            antineoplastic agent 16561
              aminoglutethimide 53
                (R)-aminoglutethimide 0
                (S)-aminoglutethimide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19657
    subatomic particle 19653
      composite particle 19653
        hadron 19653
          baryon 19653
            nucleon 19653
              atomic nucleus 19653
                atom 19653
                  main group element atom 19534
                    main group molecular entity 19534
                      s-block molecular entity 19319
                        hydrogen molecular entity 19310
                          hydrides 18237
                            inorganic hydride 17105
                              pnictogen hydride 17063
                                nitrogen hydride 16886
                                  azane 16564
                                    ammonia 16561
                                      organic amino compound 16560
                                        aromatic amine 13570
                                          anilines 12281
                                            substituted aniline 11776
                                              aminoglutethimide 53
                                                (R)-aminoglutethimide 0
                                                (S)-aminoglutethimide 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.