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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:purine nucleoside
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Accession:CHEBI:26394 term browser browse the term
Synonyms:related_synonym: purine nucleosides

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2',3'-dideoxyadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 multiple interactions ISO Dideoxyadenosine inhibits the reaction [[EGF protein co-treated with 1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone] results in decreased activity of ABCC2 protein]; Dideoxyadenosine inhibits the reaction [Taurolithocholic Acid affects the localization of ABCC2 protein]; Dideoxyadenosine inhibits the reaction [Taurolithocholic Acid results in decreased activity of ABCC2 protein] CTD PMID:25813982 PMID:31300867 NCBI chr19:43,782,308...43,838,332
Ensembl chr19:43,782,192...43,840,740 		JBrowse link
G Egf epidermal growth factor multiple interactions ISO Dideoxyadenosine inhibits the reaction [[EGF protein co-treated with 1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone] results in decreased activity of ABCC2 protein] CTD PMID:25813982 NCBI chr 3:129,677,574...129,755,322
Ensembl chr 3:129,677,565...129,755,316 		JBrowse link
2'-deoxyadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) decreases expression ISO 2'-deoxyadenosine results in decreased expression of CDKN1A mRNA CTD PMID:24211769 NCBI chr17:29,090,979...29,100,722
Ensembl chr17:29,090,976...29,100,727 		JBrowse link
G Polb polymerase (DNA directed), beta multiple interactions ISO [diepoxybutane binds to 2'-deoxyadenosine] which results in decreased activity of POLB protein CTD PMID:26098310 NCBI chr 8:22,628,119...22,653,464
Ensembl chr 8:22,628,126...22,653,435 		JBrowse link
G Poli polymerase (DNA directed), iota multiple interactions ISO [diepoxybutane binds to 2'-deoxyadenosine] which results in decreased activity of POLI protein; POLN protein inhibits the reaction [[diepoxybutane binds to 2'-deoxyadenosine] which results in decreased activity of POLI protein] CTD PMID:26098310 NCBI chr18:70,508,680...70,534,950
Ensembl chr18:70,508,680...70,530,620 		JBrowse link
G Polk polymerase (DNA directed), kappa multiple interactions ISO [diepoxybutane binds to 2'-deoxyadenosine] which results in decreased activity of POLK protein CTD PMID:26098310 NCBI chr13:96,480,687...96,542,579
Ensembl chr13:96,480,690...96,542,579 		JBrowse link
G Poln DNA polymerase N multiple interactions ISO [diepoxybutane binds to 2'-deoxyadenosine] which results in decreased activity of POLN protein; POLN protein inhibits the reaction [[diepoxybutane binds to 2'-deoxyadenosine] which results in decreased activity of POLI protein] CTD PMID:26098310 NCBI chr 5:34,007,179...34,169,526
Ensembl chr 5:34,007,179...34,169,448 		JBrowse link
G Slc29a1 solute carrier family 29 (nucleoside transporters), member 1 multiple interactions EXP 2'-deoxyadenosine inhibits the reaction [SLC29A1 protein results in increased uptake of Uridine] CTD PMID:11085929 NCBI chr17:45,585,200...45,599,618
Ensembl chr17:45,585,200...45,599,606 		JBrowse link
G Slc29a2 solute carrier family 29 (nucleoside transporters), member 2 multiple interactions EXP 2'-deoxyadenosine inhibits the reaction [SLC29A2 protein results in increased uptake of Uridine] CTD PMID:11085929 NCBI chr19:5,019,057...5,031,972
Ensembl chr19:5,023,860...5,031,972 		JBrowse link
2'-deoxyguanosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO [9-deaza-9-(3-thienylmethyl)guanine co-treated with Deoxyguanosine] results in increased activity of CASP3 protein; Deoxycytidine inhibits the reaction [[9-deaza-9-(3-thienylmethyl)guanine co-treated with Deoxyguanosine] results in increased activity of CASP3 protein] CTD PMID:9297556 PMID:9403342 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO CYP1A1 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr 9:57,687,928...57,703,824
Ensembl chr 9:57,687,928...57,703,824 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO CYP1A2 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine]; CYP1A2 protein promotes the reaction [Estrone binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr 9:57,676,937...57,683,655
Ensembl chr 9:57,676,937...57,683,703 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO CYP1B1 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr17:79,706,940...79,715,061
Ensembl chr17:79,701,537...79,715,061 		JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 multiple interactions ISO CYP3A4 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine]; CYP3A4 protein promotes the reaction [Estrone binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr 5:145,854,607...145,879,854
Ensembl chr 5:145,854,426...145,879,964 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases activity ISO Deoxyguanosine analog results in decreased activity of MGMT protein CTD PMID:17880193 NCBI chr 7:136,894,463...137,128,193
Ensembl chr 7:136,894,614...137,130,266 		JBrowse link
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 affects activity ISO Puromycin Aminonucleoside affects the activity of ACE protein CTD PMID:1318808 NCBI chr11:105,967,948...105,989,964
Ensembl chr11:105,967,945...105,989,964 		JBrowse link
G Acmsd amino carboxymuconate semialdehyde decarboxylase decreases activity ISO Puromycin Aminonucleoside results in decreased activity of ACMSD protein CTD PMID:16711654 NCBI chr 1:127,729,413...127,767,564
Ensembl chr 1:127,729,413...127,767,978 		JBrowse link
G Actb actin, beta decreases expression ISO Puromycin Aminonucleoside results in decreased expression of ACTB protein CTD PMID:19264907 NCBI chr 5:142,903,115...142,907,976
Ensembl chr 5:142,903,115...142,906,754 		JBrowse link
G Actg1 actin, gamma, cytoplasmic 1 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of ACTG1 protein CTD PMID:19264907 NCBI chr11:120,345,687...120,348,495
Ensembl chr11:120,345,690...120,348,542 		JBrowse link
G Actr2 ARP2 actin-related protein 2 increases expression ISO Puromycin Aminonucleoside results in increased expression of ACTR2 mRNA; Puromycin Aminonucleoside results in increased expression of ACTR2 protein CTD PMID:19617259 NCBI chr11:20,062,304...20,112,951
Ensembl chr11:20,062,304...20,112,913 		JBrowse link
G Actr3 ARP3 actin-related protein 3 increases expression ISO Puromycin Aminonucleoside results in increased expression of ACTR3 protein CTD PMID:19264907 NCBI chr 1:125,392,905...125,435,727
Ensembl chr 1:125,392,905...125,435,727 		JBrowse link
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) affects expression
decreases expression
increases expression
multiple interactions		 ISO Puromycin Aminonucleoside affects the expression of AGT protein
Puromycin Aminonucleoside results in decreased expression of AGT protein
Puromycin Aminonucleoside results in increased expression of AGT mRNA
[Puromycin Aminonucleoside co-treated with Cholesterol] results in increased expression of AGT mRNA		 CTD PMID:2236972 PMID:8446257 PMID:12495295 NCBI chr 8:124,556,587...124,569,706
Ensembl chr 8:124,556,534...124,569,706 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 multiple interactions
increases expression		 ISO [Puromycin Aminonucleoside co-treated with Cholesterol] results in increased expression of AGTR2 mRNA
Puromycin Aminonucleoside results in increased expression of AGTR2 mRNA		 CTD PMID:12495295 NCBI chr  X:21,484,624...21,488,833
Ensembl chr  X:21,484,544...21,489,164 		JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 increases expression ISO Puromycin Aminonucleoside results in increased expression of AGXT2 protein CTD PMID:19264907 NCBI chr15:10,358,516...10,410,158
Ensembl chr15:10,358,532...10,410,153 		JBrowse link
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 multiple interactions
affects localization		 EXP Dexamethasone inhibits the reaction [Puromycin Aminonucleoside affects the localization of AIFM1 protein] CTD PMID:15987750 NCBI chr  X:48,474,944...48,513,563
Ensembl chr  X:48,474,944...48,513,563 		JBrowse link
G Alb albumin affects transport
increases secretion
increases expression
affects localization
decreases expression		 EXP
ISO		 Puromycin Aminonucleoside affects the transport of ALB protein
Puromycin Aminonucleoside results in increased secretion of ALB protein
Puromycin Aminonucleoside results in increased expression of ALB mRNA; Puromycin Aminonucleoside results in increased expression of ALB protein
Puromycin Aminonucleoside affects the localization of ALB protein
Puromycin Aminonucleoside results in decreased expression of ALB protein		 CTD PMID:1453496 PMID:3301049 PMID:8413769 PMID:15798086 PMID:19264907 PMID:20438795 PMID:20540862 NCBI chr 5:90,460,870...90,476,602
Ensembl chr 5:90,460,897...90,476,602 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 increases expression ISO Puromycin Aminonucleoside results in increased expression of ALDH1A2 mRNA CTD PMID:12660332 NCBI chr 9:71,215,789...71,296,243
Ensembl chr 9:71,215,789...71,296,243 		JBrowse link
G Angpt1 angiopoietin 1 increases expression ISO Puromycin Aminonucleoside results in increased expression of ANGPT1 mRNA CTD PMID:17667850 NCBI chr15:42,424,667...42,676,977
Ensembl chr15:42,424,723...42,676,977 		JBrowse link
G Apex1 apurinic/apyrimidinic endonuclease 1 multiple interactions
increases expression		 EXP 1,3-dimethylthiourea inhibits the reaction [Puromycin Aminonucleoside results in increased expression of APEX1 protein] CTD PMID:17035936 NCBI chr14:50,924,949...50,927,188
Ensembl chr14:50,924,968...50,927,139 		JBrowse link
G Apoa1 apolipoprotein A-I decreases response to substance
increases expression		 ISO APOA1 protein results in decreased susceptibility to Puromycin Aminonucleoside
Puromycin Aminonucleoside results in increased expression of APOA1 mRNA; Puromycin Aminonucleoside results in increased expression of APOA1 protein		 CTD PMID:7066357 PMID:7442475 PMID:7595070 PMID:8412754 PMID:8413767 PMID:8506949 PMID:9059516 NCBI chr 9:46,228,630...46,230,469
Ensembl chr 9:46,228,580...46,230,466 		JBrowse link
G Apoa2 apolipoprotein A-II increases expression ISO Puromycin Aminonucleoside results in increased expression of APOA2 protein CTD PMID:7442475 NCBI chr 1:171,221,564...171,226,379
Ensembl chr 1:171,225,054...171,226,379 		JBrowse link
G Apoa4 apolipoprotein A-IV decreases expression
increases expression		 ISO Puromycin Aminonucleoside results in decreased expression of APOA4 protein
Puromycin Aminonucleoside results in increased expression of APOA4 mRNA; Puromycin Aminonucleoside results in increased expression of APOA4 protein		 CTD PMID:7442475 PMID:8412754 NCBI chr 9:46,240,844...46,243,458
Ensembl chr 9:46,240,696...46,243,459 		JBrowse link
G Apob apolipoprotein B increases expression ISO Puromycin Aminonucleoside results in increased expression of APOB protein CTD PMID:2725289 PMID:7442475 PMID:8506949 NCBI chr12:7,977,629...8,016,839
Ensembl chr12:7,977,648...8,016,835 		JBrowse link
G Apoe apolipoprotein E decreases response to substance
increases expression
affects expression		 EXP
ISO		 APOE protein results in decreased susceptibility to Puromycin Aminonucleoside
Puromycin Aminonucleoside results in increased expression of APOE protein
Puromycin Aminonucleoside affects the expression of APOE mRNA		 CTD PMID:7442475 PMID:8413767 PMID:12472773 NCBI chr 7:19,696,244...19,701,310
Ensembl chr 7:19,696,109...19,699,188 		JBrowse link
G Aqp2 aquaporin 2 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of AQP2 protein CTD PMID:9013444 NCBI chr15:99,579,056...99,584,545
Ensembl chr15:99,579,055...99,584,547 		JBrowse link
G Aqp3 aquaporin 3 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of AQP3 protein CTD PMID:9013444 NCBI chr 4:41,092,724...41,098,183
Ensembl chr 4:41,092,722...41,098,183 		JBrowse link
G Arc activity regulated cytoskeletal-associated protein increases expression ISO Puromycin Aminonucleoside results in increased expression of ARC mRNA CTD PMID:19617259 NCBI chr15:74,669,081...74,672,570
Ensembl chr15:74,669,083...74,672,570 		JBrowse link
G Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide decreases expression
increases expression		 ISO Puromycin Aminonucleoside results in decreased expression of ATP1A1 protein
Puromycin Aminonucleoside results in increased expression of ATP1A1 mRNA		 CTD PMID:11675400 PMID:15075188 NCBI chr 3:101,576,219...101,604,707
Ensembl chr 3:101,576,219...101,604,684 		JBrowse link
G Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide increases expression ISO Puromycin Aminonucleoside results in increased expression of ATP1B1 mRNA CTD PMID:11675400 NCBI chr 1:164,437,099...164,458,355
Ensembl chr 1:164,437,109...164,458,355 		JBrowse link
G Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of ATP2A2 mRNA; Puromycin Aminonucleoside results in decreased expression of ATP2A2 protein CTD PMID:17457379 NCBI chr 5:122,453,513...122,502,225
Ensembl chr 5:122,453,513...122,502,225 		JBrowse link
G Avp arginine vasopressin increases expression ISO Puromycin Aminonucleoside results in increased expression of AVP protein CTD PMID:7810534 NCBI chr 2:130,580,620...130,582,588
Ensembl chr 2:130,580,620...130,582,554 		JBrowse link
G Bax BCL2-associated X protein increases expression
multiple interactions		 EXP
ISO		 Puromycin Aminonucleoside results in increased expression of BAX protein
Dinoprostone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of BAX protein]
Dexamethasone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of BAX protein]		 CTD PMID:15113391 PMID:15987750 PMID:16152783 PMID:16396944 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898 		JBrowse link
G Bcat2 branched chain aminotransferase 2, mitochondrial decreases activity
decreases expression		 ISO Puromycin Aminonucleoside results in decreased activity of BCAT2 protein
Puromycin Aminonucleoside results in decreased expression of BCAT2 mRNA		 CTD PMID:9399633 NCBI chr 7:45,568,967...45,589,710
Ensembl chr 7:45,570,153...45,589,711 		JBrowse link
G Bche butyrylcholinesterase increases activity ISO Puromycin Aminonucleoside results in increased activity of BCHE protein CTD PMID:1462003 NCBI chr 3:73,635,805...73,708,436
Ensembl chr 3:73,635,808...73,708,415 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions
increases expression		 ISO [Puromycin Aminonucleoside co-treated with Melatonin] results in increased expression of BCL2 protein
Puromycin Aminonucleoside results in increased expression of BCL2 protein		 CTD PMID:14993511 PMID:15113391 PMID:16152783 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274 		JBrowse link
G Bcl2l1 BCL2-like 1 multiple interactions
decreases expression		 EXP
ISO		 [Puromycin Aminonucleoside co-treated with pifithrin] results in increased expression of BCL2L1 protein; Dexamethasone inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of BCL2L1 protein]
Dinoprostone affects the reaction [Puromycin Aminonucleoside results in decreased expression of BCL2L1 protein]		 CTD PMID:15987750 PMID:16396944 NCBI chr 2:152,758,732...152,833,803
Ensembl chr 2:152,780,668...152,831,728 		JBrowse link
G Bglap bone gamma carboxyglutamate protein increases expression ISO Puromycin Aminonucleoside results in increased expression of BGLAP protein CTD PMID:9154658 NCBI chr 3:88,383,495...88,384,466
Ensembl chr 3:88,383,501...88,384,464 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression ISO Puromycin Aminonucleoside results in increased expression of BIRC5 mRNA; Puromycin Aminonucleoside results in increased expression of BIRC5 protein CTD PMID:19617259 NCBI chr11:117,849,237...117,855,743
Ensembl chr11:117,849,251...117,855,743 		JBrowse link
G Bmp7 bone morphogenetic protein 7 multiple interactions
decreases expression		 ISO 1,25-dihydroxyvitamin D inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of BMP7 mRNA]; 1,25-dihydroxyvitamin D inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of BMP7 protein]
Puromycin Aminonucleoside results in decreased expression of BMP7 mRNA; Puromycin Aminonucleoside results in decreased expression of BMP7 protein		 CTD PMID:19594554 NCBI chr 2:172,868,012...172,940,321
Ensembl chr 2:172,868,012...172,940,321 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor, type II (serine/threonine kinase) multiple interactions
increases expression		 ISO Drugs, Chinese Herbal inhibits the reaction [Puromycin Aminonucleoside results in increased expression of BMPR2 mRNA]; Fosinopril inhibits the reaction [Puromycin Aminonucleoside results in increased expression of BMPR2 mRNA] CTD PMID:17803470 NCBI chr 1:59,764,279...59,878,081
Ensembl chr 1:59,763,400...59,879,014 		JBrowse link
G C3 complement component 3 multiple interactions
increases expression
decreases expression		 ISO cobra venom factor inhibits the reaction [Puromycin Aminonucleoside results in increased expression of C3 protein]; mizoribine inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of C3 protein] CTD PMID:8919236 PMID:9250166 NCBI chr17:57,203,967...57,228,136
Ensembl chr17:57,203,970...57,228,136 		JBrowse link
G C9 complement component 9 multiple interactions ISO CR1 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of [C5 protein alternative form binds to C9 protein]]
cobra venom factor inhibits the reaction [Puromycin Aminonucleoside results in increased expression of [C5 protein alternative form binds to C9 protein]]; Puromycin Aminonucleoside results in increased expression of [C5 protein alternative form binds to C9 protein]		 CTD PMID:9250166 NCBI chr15:6,445,346...6,498,825
Ensembl chr15:6,445,327...6,498,751 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity		 ISO Colforsin inhibits the reaction [Puromycin Aminonucleoside results in increased activity of CASP3 protein]; Dinoprostone inhibits the reaction [Puromycin Aminonucleoside results in increased activity of CASP3 protein]; L-161982 promotes the reaction [Puromycin Aminonucleoside results in increased activity of CASP3 protein] CTD PMID:16396944 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689 		JBrowse link
G Cat catalase increases activity
decreases activity
decreases expression
affects activity
multiple interactions		 EXP
ISO		 Puromycin Aminonucleoside results in increased activity of CAT protein
Puromycin Aminonucleoside results in decreased activity of CAT protein
Puromycin Aminonucleoside results in decreased expression of CAT mRNA
Puromycin Aminonucleoside affects the activity of CAT protein
[Methylprednisolone co-treated with Puromycin Aminonucleoside] results in increased activity of CAT protein; Cyclosporine inhibits the reaction [Puromycin Aminonucleoside results in decreased activity of CAT protein]; Puromycin Aminonucleoside results in decreased expression of and results in decreased activity of CAT protein; sho-saiko-to-kyo-shokyo-ka-oren-bukuryo inhibits the reaction [Puromycin Aminonucleoside results in decreased activity of CAT protein]		 CTD PMID:1744988 PMID:1942778 PMID:6246912 PMID:8289993 PMID:9355075 PMID:10468195 PMID:15113391 PMID:15496159 PMID:20685819 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160 		JBrowse link
G Ccl1 chemokine (C-C motif) ligand 1 affects expression ISO Puromycin Aminonucleoside affects the expression of CCL1 mRNA CTD PMID:10867541 NCBI chr11:82,176,666...82,179,812
Ensembl chr11:82,176,657...82,305,690 		JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 multiple interactions
increases expression
affects expression		 ISO fluvastatin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of CCL2 mRNA]; Tretinoin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of CCL2 protein]
Puromycin Aminonucleoside results in increased expression of CCL2 mRNA; Puromycin Aminonucleoside results in increased expression of CCL2 protein
Puromycin Aminonucleoside affects the expression of CCL2 mRNA		 CTD PMID:10867541 PMID:12813006 PMID:16452496 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453 		JBrowse link
G Ccl3 chemokine (C-C motif) ligand 3 affects expression ISO Puromycin Aminonucleoside affects the expression of CCL3 mRNA CTD PMID:10867541 NCBI chr11:83,647,843...83,649,378
Ensembl chr11:83,647,844...83,649,355 		JBrowse link
G Ccl7 chemokine (C-C motif) ligand 7 affects expression ISO Puromycin Aminonucleoside affects the expression of CCL7 mRNA CTD PMID:10867541 NCBI chr11:82,045,712...82,047,525
Ensembl chr11:82,045,712...82,047,525 		JBrowse link
G Cd2ap CD2-associated protein multiple interactions
decreases expression		 ISO celecoxib inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of CD2AP mRNA] CTD PMID:19194550 NCBI chr17:42,748,887...42,876,707
Ensembl chr17:42,792,951...42,876,665 		JBrowse link
G Cd36 CD36 molecule multiple interactions
increases expression		 EXP
ISO		 Puromycin Aminonucleoside results in increased expression of and results in increased glycosylation of CD36 protein
Puromycin Aminonucleoside results in increased expression of CD36 mRNA		 CTD PMID:19264907 NCBI chr 5:17,781,690...17,888,959
Ensembl chr 5:17,781,690...17,888,801 		JBrowse link
G Cd44 CD44 antigen increases expression ISO Puromycin Aminonucleoside results in increased expression of CD44 protein CTD PMID:8635280 NCBI chr 2:102,811,141...102,901,669
Ensembl chr 2:102,811,141...102,901,665 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) multiple interactions
increases expression		 EXP
ISO		 1,3-dimethylthiourea inhibits the reaction [Puromycin Aminonucleoside results in increased expression of CDKN1A protein] CTD PMID:17035936 NCBI chr17:29,090,979...29,100,722
Ensembl chr17:29,090,976...29,100,727 		JBrowse link
G Chst11 carbohydrate sulfotransferase 11 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of CHST11 mRNA CTD PMID:15585670 NCBI chr10:82,984,440...83,195,904
Ensembl chr10:82,985,498...83,195,900 		JBrowse link
G Chsy1 chondroitin sulfate synthase 1 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of CHSY1 mRNA CTD PMID:15585670 NCBI chr 7:66,109,492...66,173,798
Ensembl chr 7:66,109,515...66,173,798 		JBrowse link
G Cldn6 claudin 6 affects localization ISO Puromycin Aminonucleoside affects the localization of CLDN6 protein CTD PMID:18367650 NCBI chr17:23,679,348...23,682,446
Ensembl chr17:23,679,249...23,682,446 		JBrowse link
G Clic5 chloride intracellular channel 5 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of CLIC5 protein CTD PMID:19264907 NCBI chr17:44,134,762...44,280,169
Ensembl chr17:44,188,584...44,280,172
Ensembl chr17:44,188,584...44,280,172 		JBrowse link
G Col1a1 collagen, type I, alpha 1 multiple interactions
increases expression		 ISO 4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide inhibits the reaction [Puromycin Aminonucleoside results in increased expression of COL1A1 mRNA] CTD PMID:9527400 PMID:16570917 NCBI chr11:94,936,224...94,953,042
Ensembl chr11:94,936,224...94,953,042 		JBrowse link
G Col3a1 collagen, type III, alpha 1 increases expression ISO Puromycin Aminonucleoside results in increased expression of COL3A1 mRNA CTD PMID:9527400 NCBI chr 1:45,311,538...45,349,706
Ensembl chr 1:45,311,538...45,349,706 		JBrowse link
G Col4a1 collagen, type IV, alpha 1 multiple interactions
increases expression		 ISO Enalapril inhibits the reaction [Puromycin Aminonucleoside results in increased expression of COL4A1 mRNA]; FR 139317 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of COL4A1 mRNA]; Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of COL4A1 mRNA] CTD PMID:1762292 PMID:9175058 NCBI chr 8:11,198,423...11,312,889
Ensembl chr 8:11,198,423...11,312,826 		JBrowse link
G Corin corin, serine peptidase decreases expression ISO Puromycin Aminonucleoside results in decreased expression of CORIN mRNA; Puromycin Aminonucleoside results in decreased expression of CORIN protein CTD PMID:20613715 NCBI chr 5:72,299,948...72,504,540
Ensembl chr 5:72,300,025...72,504,473 		JBrowse link
G Ctnnb1 catenin (cadherin associated protein), beta 1 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of CTNNB1 protein CTD PMID:12065681 NCBI chr 9:120,933,400...120,960,507
Ensembl chr 9:120,929,216...120,960,507 		JBrowse link
G Ctsb cathepsin B decreases activity ISO Puromycin Aminonucleoside results in decreased activity of CTSB protein CTD PMID:10394110 NCBI chr14:63,122,462...63,145,923
Ensembl chr14:63,122,462...63,145,923 		JBrowse link
G Ctsd cathepsin D increases activity ISO Puromycin Aminonucleoside results in increased activity of CTSD protein CTD PMID:6497855 NCBI chr 7:142,375,910...142,387,827
Ensembl chr 7:142,375,911...142,388,038 		JBrowse link
G Ctsh cathepsin H decreases activity ISO Puromycin Aminonucleoside results in decreased activity of CTSH protein CTD PMID:10394110 NCBI chr 9:90,054,267...90,076,095
Ensembl chr 9:90,054,152...90,076,089 		JBrowse link
G Ctsl cathepsin L decreases response to substance
multiple interactions
decreases activity
affects expression		 EXP
ISO		 CTSL gene mutant form results in decreased susceptibility to Puromycin Aminonucleoside
Puromycin Aminonucleoside results in increased activity of and results in increased expression of CTSL protein
Puromycin Aminonucleoside results in decreased activity of CTSL protein
Puromycin Aminonucleoside affects the expression of CTSL mRNA; Puromycin Aminonucleoside affects the expression of CTSL protein		 CTD PMID:10394110 PMID:15197181 NCBI chr13:64,361,890...64,370,772
Ensembl chr13:64,359,337...64,370,890 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
decreases expression		 ISO [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of CYP11A1 mRNA]; CGB3 protein inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of CYP11A1 mRNA]; FSHB protein inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of CYP11A1 mRNA] CTD PMID:16574160 NCBI chr 9:57,998,024...58,027,031
Ensembl chr 9:58,006,411...58,027,023 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 increases expression ISO Puromycin Aminonucleoside results in increased expression of CYP24A1 mRNA CTD PMID:19297354 NCBI chr 2:170,482,957...170,497,145
Ensembl chr 2:170,482,708...170,497,145 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of CYP27B1 mRNA CTD PMID:19297354 NCBI chr10:127,048,246...127,054,884
Ensembl chr10:127,048,250...127,053,006 		JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of CYP2B1 protein CTD PMID:12806184 NCBI chr 7:25,897,658...25,926,624
Ensembl chr 7:25,897,620...25,926,624 		JBrowse link
G Ddc dopa decarboxylase decreases activity ISO Puromycin Aminonucleoside results in decreased activity of DDC protein CTD PMID:16204272 NCBI chr11:11,814,101...11,898,144
Ensembl chr11:11,814,101...11,898,144 		JBrowse link
G Ddn dendrin decreases expression ISO Puromycin Aminonucleoside results in decreased expression of DDN protein CTD PMID:20588063 NCBI chr15:98,803,782...98,807,925
Ensembl chr15:98,803,777...98,809,490 		JBrowse link
G Des desmin increases expression
multiple interactions		 ISO Puromycin Aminonucleoside results in increased expression of DES protein
triptolide inhibits the reaction [Puromycin Aminonucleoside results in increased expression of DES protein]		 CTD PMID:2183627 PMID:18509322 NCBI chr 1:75,360,292...75,368,579
Ensembl chr 1:75,360,329...75,368,579 		JBrowse link
G Dnm3 dynamin 3 increases expression ISO Puromycin Aminonucleoside results in increased expression of DNM3 mRNA CTD PMID:19617259 NCBI chr 1:161,982,450...162,478,321
Ensembl chr 1:161,982,453...162,478,034 		JBrowse link
G Ece1 endothelin converting enzyme 1 increases expression ISO Puromycin Aminonucleoside results in increased expression of ECE1 mRNA; Puromycin Aminonucleoside results in increased expression of ECE1 protein CTD PMID:12972712 NCBI chr 4:137,862,237...137,965,229
Ensembl chr 4:137,862,237...137,965,229 		JBrowse link
G Echs1 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial decreases expression ISO Puromycin Aminonucleoside results in decreased expression of ECHS1 protein CTD PMID:19264907 NCBI chr 7:140,105,710...140,116,421
Ensembl chr 7:140,105,710...140,116,476 		JBrowse link
G Edn1 endothelin 1 multiple interactions
increases expression		 ISO Enalapril inhibits the reaction [Puromycin Aminonucleoside results in increased expression of EDN1 mRNA]; FR 139317 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of EDN1 mRNA]; Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of EDN1 mRNA]; Puromycin Aminonucleoside inhibits the reaction [EDN1 protein results in increased abundance of Cyclic GMP] CTD PMID:7756592 PMID:9175058 PMID:12972712 NCBI chr13:42,301,476...42,307,990
Ensembl chr13:42,301,476...42,307,990 		JBrowse link
G Edn3 endothelin 3 multiple interactions ISO Puromycin Aminonucleoside promotes the reaction [EDN3 protein results in increased abundance of Cyclic GMP] CTD PMID:12972712 NCBI chr 2:174,760,619...174,784,042
Ensembl chr 2:174,760,619...174,784,042 		JBrowse link
G Ednra endothelin receptor type A increases expression ISO Puromycin Aminonucleoside results in increased expression of EDNRA mRNA CTD PMID:12972712 NCBI chr 8:77,663,029...77,724,452
Ensembl chr 8:77,663,031...77,724,464 		JBrowse link
G Ednrb endothelin receptor type B multiple interactions
increases expression		 ISO Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of EDNRB mRNA] CTD PMID:7756592 NCBI chr14:103,814,615...103,844,508
Ensembl chr14:103,814,625...103,844,402 		JBrowse link
G Etfa electron transferring flavoprotein, alpha polypeptide decreases expression ISO Puromycin Aminonucleoside results in decreased expression of ETFA protein CTD PMID:19264907 NCBI chr 9:55,454,436...55,512,243
Ensembl chr 9:55,454,508...55,512,243 		JBrowse link
G Etfb electron transferring flavoprotein, beta polypeptide decreases expression ISO Puromycin Aminonucleoside results in decreased expression of ETFB protein CTD PMID:19264907 NCBI chr 7:43,444,072...43,457,800
Ensembl chr 7:43,444,083...43,457,800 		JBrowse link
G Ezr ezrin decreases expression ISO Puromycin Aminonucleoside results in decreased expression of EZR protein CTD PMID:19264907 NCBI chr17:6,738,131...6,782,780
Ensembl chr17:6,738,041...6,782,784 		JBrowse link
G Fas Fas (TNF receptor superfamily member 6) multiple interactions
increases expression		 ISO Melatonin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of FAS protein] CTD PMID:14993511 PMID:16152783 NCBI chr19:34,290,647...34,327,775
Ensembl chr19:34,290,666...34,327,772 		JBrowse link
G Fasl Fas ligand (TNF superfamily, member 6) increases expression
multiple interactions		 ISO Puromycin Aminonucleoside results in increased expression of FASL protein
Melatonin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of FASLG protein]		 CTD PMID:14993511 PMID:16152783 NCBI chr 1:161,780,691...161,788,495
Ensembl chr 1:161,780,689...161,788,495 		JBrowse link
G Fat1 FAT atypical cadherin 1 increases expression ISO Puromycin Aminonucleoside results in increased expression of FAT1 mRNA; Puromycin Aminonucleoside results in increased expression of FAT1 protein CTD PMID:16014031 NCBI chr 8:44,933,100...45,052,257
Ensembl chr 8:44,935,447...45,052,257 		JBrowse link
G Flt1 FMS-like tyrosine kinase 1 increases expression
affects expression		 ISO Puromycin Aminonucleoside results in increased expression of FLT1 protein
Puromycin Aminonucleoside affects the expression of FLT1 mRNA		 CTD PMID:11744811 PMID:14752241 NCBI chr 5:147,561,604...147,726,438
Ensembl chr 5:147,561,604...147,726,011 		JBrowse link
G Fn1 fibronectin 1 increases expression
multiple interactions		 ISO Puromycin Aminonucleoside results in increased expression of FN1 mRNA; Puromycin Aminonucleoside results in increased expression of FN1 protein
Tretinoin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of FN1 protein]		 CTD PMID:9527400 PMID:12813006 NCBI chr 1:71,585,473...71,653,280
Ensembl chr 1:71,585,520...71,653,200 		JBrowse link
G Fshb follicle stimulating hormone beta multiple interactions
decreases expression		 ISO [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased abundance of Estradiol]; [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased abundance of Progesterone]; [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased abundance of Testosterone]; [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of CYP11A1 mRNA]; [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of STAR mRNA]; FSHB protein inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of CYP11A1 mRNA]; Puromycin Aminonucleoside inhibits the reaction [GNRH1 protein results in increased secretion of FSHB protein]
Puromycin Aminonucleoside results in decreased expression of FSHB protein		 CTD PMID:12269381 PMID:16574160 NCBI chr 2:107,055,986...107,059,651
Ensembl chr 2:107,056,140...107,059,656 		JBrowse link
G Gnaq guanine nucleotide binding protein, alpha q polypeptide increases response to substance EXP GNAQ protein results in increased susceptibility to Puromycin Aminonucleoside CTD PMID:16267159 NCBI chr19:16,132,684...16,388,520
Ensembl chr19:16,132,831...16,387,463 		JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 multiple interactions ISO Puromycin Aminonucleoside inhibits the reaction [GNRH1 protein results in increased secretion of FSHB protein]; Puromycin Aminonucleoside inhibits the reaction [GNRH1 protein results in increased secretion of LHB protein] CTD PMID:12269381 NCBI chr14:67,745,181...67,749,440
Ensembl chr14:67,745,181...67,749,439 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
increases expression		 ISO [Methylprednisolone co-treated with Puromycin Aminonucleoside] results in increased activity of GPX1 protein
Puromycin Aminonucleoside results in increased expression of GPX1 mRNA		 CTD PMID:1942778 PMID:20685819 NCBI chr 9:108,339,080...108,340,342
Ensembl chr 9:108,338,903...108,340,343 		JBrowse link
G Gpx3 glutathione peroxidase 3 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of GPX3 mRNA CTD PMID:20685819 NCBI chr11:54,902,854...54,910,387
Ensembl chr11:54,902,453...54,910,377 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation		 ISO mizoribine inhibits the reaction [Puromycin Aminonucleoside results in increased phosphorylation of GSK3B protein] CTD PMID:20502051 NCBI chr16:38,089,001...38,246,084
Ensembl chr16:38,089,001...38,246,084 		JBrowse link
G Gstp1 glutathione S-transferase, pi 1 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of GSTP1 protein CTD PMID:19264907 NCBI chr19:4,035,411...4,037,912
Ensembl chr19:4,035,407...4,037,985 		JBrowse link
G Guca2b guanylate cyclase activator 2b (retina) increases expression
affects expression		 ISO Puromycin Aminonucleoside results in increased expression of GUCA2B protein
Puromycin Aminonucleoside affects the expression of GUCA2B mRNA		 CTD PMID:15590761 NCBI chr 4:119,656,601...119,658,945
Ensembl chr 4:119,656,607...119,658,954 		JBrowse link
G Hadh hydroxyacyl-Coenzyme A dehydrogenase decreases expression EXP
ISO		 Puromycin Aminonucleoside results in decreased expression of HADH protein CTD PMID:19264907 NCBI chr 3:131,233,419...131,272,101
Ensembl chr 3:131,233,419...131,272,101 		JBrowse link
G Hc hemolytic complement multiple interactions ISO CR1 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of [C5 protein alternative form binds to C9 protein]]
cobra venom factor inhibits the reaction [Puromycin Aminonucleoside results in increased expression of [C5 protein alternative form binds to C9 protein]]; Puromycin Aminonucleoside results in increased expression of [C5 protein alternative form binds to C9 protein]		 CTD PMID:9250166 NCBI chr 2:34,983,329...35,068,506
Ensembl chr 2:34,983,331...35,061,438 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase increases activity ISO Puromycin Aminonucleoside results in increased activity of HMGCR protein CTD PMID:3794548 NCBI chr13:96,648,962...96,670,936
Ensembl chr13:96,648,967...96,670,936 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression		 ISO [piperine co-treated with Cimetidine co-treated with Pyruvates] inhibits the reaction [Puromycin Aminonucleoside results in increased expression of HMOX1 protein]
Puromycin Aminonucleoside results in increased expression of HMOX1 mRNA; Puromycin Aminonucleoside results in increased expression of HMOX1 protein		 CTD PMID:12806184 PMID:20685819 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589 		JBrowse link
G Hpse heparanase increases expression ISO Puromycin Aminonucleoside results in increased expression of HPSE mRNA; Puromycin Aminonucleoside results in increased expression of HPSE protein CTD PMID:11576343 NCBI chr 5:100,679,484...100,719,716
Ensembl chr 5:100,679,484...100,719,716 		JBrowse link
G Hs3st1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of HS3ST1 mRNA CTD PMID:15585670 NCBI chr 5:39,613,935...39,645,592
Ensembl chr 5:39,613,935...39,755,475 		JBrowse link
G Hs6st1 heparan sulfate 6-O-sulfotransferase 1 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of HS6ST1 mRNA CTD PMID:15585670 NCBI chr 1:36,068,400...36,106,446
Ensembl chr 1:36,068,400...36,106,446 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 decreases activity ISO Puromycin Aminonucleoside results in decreased activity of HSD11B2 protein CTD PMID:11981059 NCBI chr 8:105,518,746...105,523,988
Ensembl chr 8:105,518,755...105,523,988 		JBrowse link
G Hspa5 heat shock protein 5 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of HSPA5 protein CTD PMID:19264907 NCBI chr 2:34,772,090...34,776,529
Ensembl chr 2:34,771,970...34,777,547 		JBrowse link
G Hspa8 heat shock protein 8 affects localization ISO Puromycin Aminonucleoside affects the localization of HSPA8 protein CTD PMID:1614035 NCBI chr 9:40,801,276...40,805,202
Ensembl chr 9:40,800,984...40,810,087 		JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) decreases expression ISO Puromycin Aminonucleoside results in decreased expression of HSPD1 protein CTD PMID:19264907 NCBI chr 1:55,077,833...55,088,243
Ensembl chr 1:55,077,835...55,088,243 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Puromycin Aminonucleoside results in increased expression of ICAM1 protein CTD PMID:8635280 NCBI chr 9:21,015,940...21,028,814
Ensembl chr 9:21,015,985...21,028,817 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO Puromycin Aminonucleoside results in increased expression of IL1B mRNA CTD PMID:17457379 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139 		JBrowse link
G Ilk integrin linked kinase multiple interactions
increases activity		 ISO mizoribine inhibits the reaction [Puromycin Aminonucleoside results in increased activity of ILK protein] CTD PMID:20502051 NCBI chr 7:105,736,590...105,742,925
Ensembl chr 7:105,736,592...105,742,925 		JBrowse link
G Itga3 integrin alpha 3 decreases expression
affects expression		 ISO Puromycin Aminonucleoside results in decreased expression of ITGA3 mRNA; Puromycin Aminonucleoside results in decreased expression of ITGA3 protein
Puromycin Aminonucleoside affects the expression of ITGA3 protein		 CTD PMID:9249603 PMID:10845833 PMID:11274237 PMID:15197181 NCBI chr11:95,044,475...95,076,844
Ensembl chr11:95,044,474...95,076,801 		JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) decreases expression
increases expression		 ISO Puromycin Aminonucleoside results in decreased expression of ITGB1 mRNA; Puromycin Aminonucleoside results in decreased expression of ITGB1 protein
Puromycin Aminonucleoside results in increased expression of ITGB1 protein		 CTD PMID:11274237 PMID:12065681 PMID:14559718 NCBI chr 8:128,685,654...128,733,579
Ensembl chr 8:128,685,654...128,733,200 		JBrowse link
G Kdr kinase insert domain protein receptor affects expression
increases expression
decreases expression		 ISO Puromycin Aminonucleoside affects the expression of KDR mRNA
Puromycin Aminonucleoside results in increased expression of KDR mRNA; Puromycin Aminonucleoside results in increased expression of KDR protein
Puromycin Aminonucleoside results in decreased expression of KDR mRNA		 CTD PMID:11744811 PMID:14752241 PMID:17667850 NCBI chr 5:75,932,827...75,979,072
Ensembl chr 5:75,932,827...75,978,458 		JBrowse link
G Kirrel kirre like nephrin family adhesion molecule 1 decreases expression
multiple interactions		 EXP Puromycin Aminonucleoside results in decreased expression of KIRREL mRNA
Y 27632 inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of KIRREL mRNA]		 CTD PMID:18367845 NCBI chr 3:87,078,593...87,174,777
Ensembl chr 3:87,078,593...87,174,747 		JBrowse link
G Krt7 keratin 7 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of KRT7 mRNA; Puromycin Aminonucleoside results in decreased expression of KRT7 protein CTD PMID:19617259 NCBI chr15:101,412,403...101,427,806
Ensembl chr15:101,411,043...101,430,313 		JBrowse link
G Lamb1 laminin B1 multiple interactions
increases expression		 ISO Enalapril inhibits the reaction [Puromycin Aminonucleoside results in increased expression of LAMB1 mRNA]; FR 139317 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of LAMB1 mRNA]; Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of LAMB1 mRNA] CTD PMID:1762292 PMID:9175058 NCBI chr12:31,265,146...31,329,644
Ensembl chr12:31,265,234...31,329,644 		JBrowse link
G Lamb2 laminin, beta 2 multiple interactions
increases expression		 ISO Enalapril inhibits the reaction [Puromycin Aminonucleoside results in increased expression of LAMB2 mRNA]; FR 139317 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of LAMB2 mRNA]; Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of LAMB2 mRNA] CTD PMID:1762292 PMID:9175058 NCBI chr 9:108,479,847...108,490,530
Ensembl chr 9:108,479,736...108,490,530 		JBrowse link
G Lcn2 lipocalin 2 increases secretion ISO Puromycin Aminonucleoside results in increased secretion of LCN2 protein CTD PMID:20438795 NCBI chr 2:32,384,637...32,387,739
Ensembl chr 2:32,384,633...32,388,252 		JBrowse link
G Lgals1 lectin, galactose binding, soluble 1 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of LGALS1 protein CTD PMID:19079321 NCBI chr15:78,926,725...78,930,465
Ensembl chr15:78,926,725...78,930,465 		JBrowse link
G Lhb luteinizing hormone beta multiple interactions
decreases expression		 ISO [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased abundance of Estradiol]; [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased abundance of Progesterone]; [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased abundance of Testosterone]; [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of CYP11A1 mRNA]; [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of STAR mRNA]; CGB3 protein inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of CYP11A1 mRNA]; Puromycin Aminonucleoside inhibits the reaction [GNRH1 protein results in increased secretion of LHB protein]
Puromycin Aminonucleoside results in decreased expression of LHB protein		 CTD PMID:12269381 PMID:16574160 NCBI chr 7:45,417,608...45,421,855
Ensembl chr 7:45,420,820...45,421,897
Ensembl chr 7:45,420,820...45,421,897 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO Puromycin Aminonucleoside results in increased expression of and results in increased phosphorylation of MAPK1 protein CTD PMID:14559718 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO Puromycin Aminonucleoside results in increased expression of and results in increased phosphorylation of MAPK3 protein CTD PMID:14559718 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Puromycin Aminonucleoside binds to and results in increased activity of MAPK8 protein CTD PMID:15351692 NCBI chr14:33,377,898...33,447,353
Ensembl chr14:33,377,898...33,447,158 		JBrowse link
G Mdk midkine multiple interactions
decreases expression		 ISO Tretinoin inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of MDK mRNA] CTD PMID:12660332 NCBI chr 2:91,929,805...91,932,297
Ensembl chr 2:91,929,805...91,932,297 		JBrowse link
G Mme membrane metallo endopeptidase decreases expression ISO Puromycin Aminonucleoside results in decreased expression of MME protein CTD PMID:19885019 NCBI chr 3:63,295,211...63,383,713
Ensembl chr 3:63,241,537...63,386,030 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression		 ISO FR 139317 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of MMP2 mRNA] CTD PMID:9175058 NCBI chr 8:92,827,290...92,853,421
Ensembl chr 8:92,827,291...92,853,420 		JBrowse link
G Msn moesin increases expression ISO Puromycin Aminonucleoside results in increased expression of MSN protein CTD PMID:19264907 NCBI chr  X:96,096,045...96,168,553
Ensembl chr  X:96,096,042...96,168,552 		JBrowse link
G mt-Co1 cytochrome c oxidase I, mitochondrial decreases expression ISO Puromycin Aminonucleoside results in decreased expression of COX1 protein CTD PMID:16609681 NCBI chr MT:5,328...6,872
Ensembl chr MT:5,328...6,872 		JBrowse link
G Myh10 myosin, heavy polypeptide 10, non-muscle increases expression
affects expression		 ISO Puromycin Aminonucleoside results in increased expression of MYH10 protein
Puromycin Aminonucleoside affects the expression of MYH10 mRNA; Puromycin Aminonucleoside affects the expression of MYH10 protein		 CTD PMID:7671567 PMID:8918620 NCBI chr11:68,691,915...68,816,626
Ensembl chr11:68,691,559...68,816,632 		JBrowse link
G Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha affects expression ISO Puromycin Aminonucleoside affects the expression of MYH6 mRNA CTD PMID:17457379 NCBI chr14:54,941,921...54,968,017
Ensembl chr14:54,941,921...54,966,927 		JBrowse link
G Napsa napsin A aspartic peptidase increases expression ISO Puromycin Aminonucleoside results in increased expression of NAPSA mRNA; Puromycin Aminonucleoside results in increased expression of NAPSA protein CTD PMID:12501893 NCBI chr 7:44,572,445...44,586,846
Ensembl chr 7:44,572,380...44,586,862 		JBrowse link
G Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 decreases expression
affects expression		 ISO Puromycin Aminonucleoside results in decreased expression of NDST1 mRNA
Puromycin Aminonucleoside affects the expression of NDST1 mRNA		 CTD PMID:14966466 NCBI chr18:60,684,494...60,749,035
Ensembl chr18:60,684,494...60,748,650 		JBrowse link
G Nebl nebulette decreases expression ISO Puromycin Aminonucleoside results in decreased expression of NEBL mRNA CTD PMID:19617259 NCBI chr 2:17,342,673...17,734,949
Ensembl chr 2:17,343,909...17,731,464 		JBrowse link
G Nedd4l neural precursor cell expressed, developmentally down-regulated gene 4-like decreases expression ISO Puromycin Aminonucleoside results in decreased expression of NEDD4L protein CTD PMID:16020936 NCBI chr18:64,884,480...65,217,826
Ensembl chr18:64,887,705...65,217,828 		JBrowse link
G Nos1 nitric oxide synthase 1, neuronal multiple interactions
increases expression		 ISO Puromycin Aminonucleoside results in decreased expression of and results in decreased activity of NOS1 protein
Puromycin Aminonucleoside results in increased expression of NOS1 mRNA		 CTD PMID:15039144 NCBI chr 5:117,866,839...117,958,840
Ensembl chr 5:117,781,032...117,958,840 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible increases expression ISO Puromycin Aminonucleoside results in increased expression of NOS2 mRNA CTD PMID:15039144 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell increases expression
multiple interactions		 ISO Puromycin Aminonucleoside results in increased expression of NOS3 mRNA
Puromycin Aminonucleoside results in decreased expression of and results in decreased activity of NOS3 protein		 CTD PMID:15039144 NCBI chr 5:24,364,816...24,384,474
Ensembl chr 5:24,364,810...24,384,474 		JBrowse link
G Nphs2 nephrosis 2, podocin decreases expression
multiple interactions
affects expression		 EXP
ISO		 Puromycin Aminonucleoside results in decreased expression of NPHS2 protein
triptolide inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS2 protein]
Puromycin Aminonucleoside affects the expression of NPHS2 mRNA; Puromycin Aminonucleoside affects the expression of NPHS2 protein		 CTD PMID:12065681 PMID:15363039 PMID:18509322 NCBI chr 1:156,310,535...156,328,035
Ensembl chr 1:156,310,727...156,328,035 		JBrowse link
G Nppa natriuretic peptide type A affects metabolic processing
increases response to substance
increases expression
multiple interactions
affects expression		 ISO Puromycin Aminonucleoside affects the metabolism of NPPA protein
Puromycin Aminonucleoside results in increased susceptibility to NPPA protein
Puromycin Aminonucleoside results in increased expression of NPPA mRNA; Puromycin Aminonucleoside results in increased expression of NPPA protein
Puromycin Aminonucleoside inhibits the reaction [NPPA protein results in increased abundance of Cyclic GMP]
Puromycin Aminonucleoside affects the expression of NPPA protein		 CTD PMID:2526952 PMID:12972712 PMID:15590761 PMID:19885019 PMID:20613715 NCBI chr 4:148,000,722...148,002,074
Ensembl chr 4:148,000,722...148,002,079 		JBrowse link
G Nppb natriuretic peptide type B affects expression ISO Puromycin Aminonucleoside affects the expression of NPPB mRNA CTD PMID:17457379 NCBI chr 4:147,985,786...147,987,205
Ensembl chr 4:147,985,788...147,987,205 		JBrowse link
G Npr1 natriuretic peptide receptor 1 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of NPR1 mRNA CTD PMID:19885019 NCBI chr 3:90,450,591...90,465,928
Ensembl chr 3:90,450,591...90,465,866 		JBrowse link
G Npr3 natriuretic peptide receptor 3 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of NPR3 mRNA CTD PMID:19885019 NCBI chr15:11,839,896...11,907,837
Ensembl chr15:11,839,896...11,907,287 		JBrowse link
G Nrf1 nuclear respiratory factor 1 affects expression ISO Puromycin Aminonucleoside affects the expression of NRF1 mRNA CTD PMID:16609681 NCBI chr 6:30,047,985...30,153,458
Ensembl chr 6:30,047,988...30,153,458 		JBrowse link
G Optn optineurin increases expression ISO Puromycin Aminonucleoside results in increased expression of OPTN protein CTD PMID:25096716 NCBI chr 2:5,020,521...5,064,399
Ensembl chr 2:5,020,642...5,064,051 		JBrowse link
G Pdpn podoplanin decreases expression EXP
ISO		 Puromycin Aminonucleoside results in decreased expression of PDPN mRNA; Puromycin Aminonucleoside results in decreased expression of PDPN protein CTD PMID:9327748 PMID:12032185 NCBI chr 4:143,267,409...143,299,564
Ensembl chr 4:143,267,431...143,299,564 		JBrowse link
G Plekhh2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of PLEKHH2 protein CTD PMID:20588063 NCBI chr17:84,511,895...84,622,143
Ensembl chr17:84,511,895...84,622,138 		JBrowse link
G Pln phospholamban increases expression ISO Puromycin Aminonucleoside results in increased expression of PLN mRNA CTD PMID:17457379 NCBI chr10:53,337,686...53,345,999
Ensembl chr10:53,337,667...53,345,987 		JBrowse link
G Podxl podocalyxin-like increases expression
affects metabolic processing		 ISO Puromycin Aminonucleoside results in increased expression of PODXL mRNA; Puromycin Aminonucleoside results in increased expression of PODXL protein
Puromycin Aminonucleoside affects the metabolism of PODXL protein		 CTD PMID:8780404 PMID:11274237 NCBI chr 6:31,519,493...31,563,937
Ensembl chr 6:31,519,488...31,563,981 		JBrowse link
G Polb polymerase (DNA directed), beta increases expression
multiple interactions		 EXP Puromycin Aminonucleoside results in increased expression of POLB protein
1,3-dimethylthiourea inhibits the reaction [Puromycin Aminonucleoside results in increased expression of POLB protein]		 CTD PMID:17035936 NCBI chr 8:22,628,119...22,653,464
Ensembl chr 8:22,628,126...22,653,435 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions
increases expression		 ISO pioglitazone affects the reaction [Puromycin Aminonucleoside results in increased expression of PPARG protein] CTD PMID:16598202 NCBI chr 6:115,360,879...115,490,404
Ensembl chr 6:115,360,951...115,490,399 		JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A increases phosphorylation
increases expression
multiple interactions		 EXP
ISO		 Puromycin Aminonucleoside results in increased phosphorylation of PPP1R12A protein
Puromycin Aminonucleoside results in increased expression of PPP1R12A protein modified form
Y 27632 inhibits the reaction [Puromycin Aminonucleoside results in increased phosphorylation of PPP1R12A protein]
fluvastatin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of PPP1R12A protein modified form]		 CTD PMID:16452496 PMID:18367845 NCBI chr10:108,162,092...108,279,985
Ensembl chr10:108,162,193...108,284,475 		JBrowse link
G Prdx3 peroxiredoxin 3 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of PRDX3 protein CTD PMID:19264907 NCBI chr19:60,864,066...60,874,538
Ensembl chr19:60,864,051...60,874,556 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
affects response to substance
multiple interactions		 EXP
ISO		 Puromycin Aminonucleoside results in increased expression of PTGS2 mRNA; Puromycin Aminonucleoside results in increased expression of PTGS2 protein
PTGS2 protein affects the susceptibility to Puromycin Aminonucleoside
celecoxib inhibits the reaction [Puromycin Aminonucleoside results in increased expression of PTGS2 mRNA]		 CTD PMID:16396944 PMID:17890881 PMID:19194550 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227 		JBrowse link
G Pth parathyroid hormone increases expression ISO Puromycin Aminonucleoside results in increased expression of PTH protein CTD PMID:1328752 NCBI chr 7:113,385,576...113,388,672
Ensembl chr 7:113,385,580...113,388,570 		JBrowse link
G Ptk2 PTK2 protein tyrosine kinase 2 multiple interactions ISO Puromycin Aminonucleoside results in increased expression of and results in increased phosphorylation of PTK2 protein CTD PMID:14559718 NCBI chr15:73,205,102...73,423,820
Ensembl chr15:73,205,102...73,423,280 		JBrowse link
G Ptpro protein tyrosine phosphatase, receptor type, O affects expression ISO Puromycin Aminonucleoside affects the expression of PTPRO mRNA; Puromycin Aminonucleoside affects the expression of PTPRO protein CTD PMID:11961407 NCBI chr 6:137,252,299...137,464,634
Ensembl chr 6:137,252,319...137,463,233 		JBrowse link
G Rara retinoic acid receptor, alpha increases expression ISO Puromycin Aminonucleoside results in increased expression of RARA mRNA; Puromycin Aminonucleoside results in increased expression of RARA protein CTD PMID:12660332 NCBI chr11:98,927,800...98,974,942
Ensembl chr11:98,927,818...98,974,942 		JBrowse link
G Rbbp7 retinoblastoma binding protein 7, chromatin remodeling factor decreases expression EXP Puromycin Aminonucleoside results in decreased expression of RBBP7 protein CTD PMID:15798086 NCBI chr  X:162,760,372...162,779,090
Ensembl chr  X:162,760,402...162,779,092 		JBrowse link
G Ren1 renin 1 structural multiple interactions
increases expression
affects expression		 ISO Puromycin Aminonucleoside affects the expression of and affects the activity of REN protein; Puromycin Aminonucleoside results in increased expression of and results in increased activity of REN protein
Puromycin Aminonucleoside results in increased expression of REN protein
Puromycin Aminonucleoside affects the expression of REN protein		 CTD PMID:2236972 PMID:2267444 PMID:8446257 PMID:9171944 NCBI chr 1:133,350,674...133,360,320
Ensembl chr 1:133,350,510...133,360,325 		JBrowse link
G Rhoa ras homolog family member A multiple interactions
increases expression		 EXP
ISO		 fluvastatin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of RHOA protein] CTD PMID:16452496 NCBI chr 9:108,306,160...108,337,943
Ensembl chr 9:108,306,129...108,337,934 		JBrowse link
G Scnn1a sodium channel, nonvoltage-gated 1 alpha affects expression
multiple interactions
decreases expression
affects localization		 ISO Puromycin Aminonucleoside affects the expression of SCNN1A mRNA
Puromycin Aminonucleoside results in increased expression of and results in increased localization of SCNN1A protein
Puromycin Aminonucleoside results in decreased expression of SCNN1A mRNA
Puromycin Aminonucleoside affects the localization of SCNN1A protein		 CTD PMID:12653683 PMID:15075188 PMID:16020936 PMID:16267158 NCBI chr 6:125,314,271...125,344,943
Ensembl chr 6:125,320,659...125,344,943 		JBrowse link
G Scnn1b sodium channel, nonvoltage-gated 1 beta affects expression
increases expression
decreases expression
multiple interactions
affects localization		 ISO Puromycin Aminonucleoside affects the expression of SCNN1B mRNA
Puromycin Aminonucleoside results in increased expression of SCNN1B mRNA
Puromycin Aminonucleoside results in decreased expression of SCNN1B mRNA
Puromycin Aminonucleoside results in increased expression of and results in increased localization of SCNN1B protein
Puromycin Aminonucleoside affects the localization of SCNN1B protein		 CTD PMID:12653683 PMID:15075188 PMID:16020936 PMID:16267158 NCBI chr 7:121,865,038...121,918,728
Ensembl chr 7:121,865,038...121,918,514 		JBrowse link
G Scnn1g sodium channel, nonvoltage-gated 1 gamma multiple interactions
increases expression
decreases expression		 ISO Puromycin Aminonucleoside affects the localization of and affects the expression of SCNN1G protein; Puromycin Aminonucleoside results in increased expression of and results in increased localization of SCNN1G protein
Puromycin Aminonucleoside results in increased expression of SCNN1G mRNA
Puromycin Aminonucleoside results in decreased expression of SCNN1G mRNA		 CTD PMID:12653683 PMID:15075188 PMID:16020936 PMID:16267158 NCBI chr 7:121,734,420...121,768,482
Ensembl chr 7:121,734,479...121,768,475 		JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 multiple interactions
increases expression		 ISO pioglitazone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of SERPINE1 mRNA] CTD PMID:16598202 NCBI chr 5:137,061,504...137,072,272
Ensembl chr 5:137,061,504...137,072,268 		JBrowse link
G Slc12a1 solute carrier family 12, member 1 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of SLC12A1 protein CTD PMID:15075188 NCBI chr 2:125,152,510...125,230,002
Ensembl chr 2:125,152,505...125,230,002 		JBrowse link
G Slc12a3 solute carrier family 12, member 3 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of SLC12A3 protein CTD PMID:15075188 NCBI chr 8:94,329,109...94,366,222
Ensembl chr 8:94,329,201...94,366,214 		JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 affects expression ISO Puromycin Aminonucleoside affects the expression of SLC22A2 mRNA CTD PMID:22005293 NCBI chr17:12,584,189...12,628,489
Ensembl chr17:12,584,132...12,628,488 		JBrowse link
G Slc29a4 solute carrier family 29 (nucleoside transporters), member 4 increases response to substance ISO SLC29A4 results in increased susceptibility to Puromycin Aminonucleoside CTD PMID:19357181 NCBI chr 5:142,692,478...142,722,490
Ensembl chr 5:142,692,512...142,722,490 		JBrowse link
G Slc5a3 solute carrier family 5 (inositol transporters), member 3 increases expression ISO Puromycin Aminonucleoside results in increased expression of SLC5A3 mRNA CTD PMID:15031335 NCBI chr16:92,058,322...92,087,473
Ensembl chr16:92,058,322...92,087,473 		JBrowse link
G Slc9a3 solute carrier family 9 (sodium/hydrogen exchanger), member 3 multiple interactions
decreases expression
affects expression		 ISO [piperine co-treated with Cimetidine co-treated with Pyruvates] inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of SLC9A3 protein]
Puromycin Aminonucleoside affects the expression of SLC9A3 protein		 CTD PMID:12191963 PMID:12806184 PMID:15075188 NCBI chr13:74,086,255...74,169,442
Ensembl chr13:74,121,457...74,169,442 		JBrowse link
G Smad1 SMAD family member 1 increases expression ISO Puromycin Aminonucleoside results in increased expression of SMAD1 mRNA CTD PMID:17803470 NCBI chr 8:79,338,395...79,399,428
Ensembl chr 8:79,338,395...79,399,518 		JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial affects expression
decreases expression
multiple interactions		 EXP
ISO		 Puromycin Aminonucleoside affects the expression of SOD2 protein
Puromycin Aminonucleoside results in decreased expression of SOD2 protein
[Methylprednisolone co-treated with Puromycin Aminonucleoside] results in increased activity of SOD2 protein		 CTD PMID:1942778 PMID:19264907 NCBI chr17:13,007,839...13,018,119
Ensembl chr17:13,006,846...13,040,063 		JBrowse link
G Sod3 superoxide dismutase 3, extracellular decreases expression ISO Puromycin Aminonucleoside results in decreased expression of SOD3 mRNA CTD PMID:20685819 NCBI chr 5:52,363,804...52,369,738
Ensembl chr 5:52,363,791...52,371,418 		JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions
increases expression		 ISO Drugs, Chinese Herbal inhibits the reaction [Puromycin Aminonucleoside results in increased expression of SPP1 protein]; fluvastatin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of SPP1 mRNA]
Puromycin Aminonucleoside results in increased expression of SPP1 mRNA; Puromycin Aminonucleoside results in increased expression of SPP1 protein		 CTD PMID:14738908 PMID:16452496 NCBI chr 5:104,435,111...104,441,053
Ensembl chr 5:104,435,118...104,441,050 		JBrowse link
G Src Rous sarcoma oncogene multiple interactions ISO Puromycin Aminonucleoside results in increased expression of and results in increased phosphorylation of SRC protein CTD PMID:14559718 NCBI chr 2:157,423,906...157,471,838
Ensembl chr 2:157,418,444...157,471,862 		JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
decreases expression		 ISO [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of STAR mRNA] CTD PMID:16574160 NCBI chr 8:25,808,474...25,815,982
Ensembl chr 8:25,806,555...25,815,982 		JBrowse link
G Synpo synaptopodin decreases expression EXP Puromycin Aminonucleoside results in decreased expression of SYNPO protein CTD PMID:15798086 NCBI chr18:60,593,981...60,660,173
Ensembl chr18:60,593,973...60,660,142 		JBrowse link
G Tagln transgelin increases expression ISO Puromycin Aminonucleoside results in increased expression of TAGLN mRNA; Puromycin Aminonucleoside results in increased expression of TAGLN protein CTD PMID:19617259 NCBI chr 9:45,929,628...45,936,058
Ensembl chr 9:45,929,619...45,936,058 		JBrowse link
G Tek TEK receptor tyrosine kinase decreases expression ISO Puromycin Aminonucleoside results in decreased expression of TEK mRNA CTD PMID:17667850 NCBI chr 4:94,739,086...94,874,976
Ensembl chr 4:94,739,289...94,874,976 		JBrowse link
G Tfam transcription factor A, mitochondrial affects expression ISO Puromycin Aminonucleoside affects the expression of TFAM mRNA CTD PMID:16609681 NCBI chr10:71,225,468...71,238,328
Ensembl chr10:71,225,464...71,238,280 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases expression
affects expression		 ISO Celecoxib inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TGFB1 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TGFB1 protein]; Masoprocol inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TGFB1 mRNA]
Puromycin Aminonucleoside results in increased expression of TGFB1 mRNA; Puromycin Aminonucleoside results in increased expression of TGFB1 protein
Puromycin Aminonucleoside affects the expression of TGFB1 mRNA		 CTD PMID:9527400 PMID:12397044 PMID:14738908 PMID:19194550 PMID:19594554 NCBI chr 7:25,687,002...25,705,077
Ensembl chr 7:25,687,002...25,705,077 		JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 multiple interactions
increases expression		 ISO FR 139317 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TIMP1 mRNA] CTD PMID:9175058 NCBI chr  X:20,870,166...20,874,737
Ensembl chr  X:20,870,166...20,874,735 		JBrowse link
G Tjp1 tight junction protein 1 multiple interactions
increases expression
affects localization		 ISO
EXP		 Cyclosporine inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TJP1 protein]
Puromycin Aminonucleoside affects the localization of TJP1 protein		 CTD PMID:15744817 PMID:15798086 NCBI chr 7:65,296,165...65,527,850
Ensembl chr 7:65,296,165...65,527,781 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression		 ISO Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TNF mRNA] CTD PMID:8384958 PMID:17457379 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007 		JBrowse link
G Tnnc1 troponin C, cardiac/slow skeletal decreases expression ISO Puromycin Aminonucleoside results in decreased expression of TNNC1 mRNA CTD PMID:19617259 NCBI chr14:31,208,312...31,211,729
Ensembl chr14:31,208,312...31,211,729 		JBrowse link
G Trf transferrin increases expression ISO Puromycin Aminonucleoside results in increased expression of TF mRNA CTD PMID:8413769 NCBI chr 9:103,208,876...103,230,286
Ensembl chr 9:103,204,001...103,230,444 		JBrowse link
G Trp53 transformation related protein 53 multiple interactions
increases expression		 ISO
EXP		 1,3-dimethylthiourea inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TP53 protein]; Melatonin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TP53 protein]
Puromycin Aminonucleoside results in increased expression of TRP53 protein
1,3-dimethylthiourea inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TRP53 protein]; Dexamethasone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TRP53 protein]		 CTD PMID:14993511 PMID:15113391 PMID:15987750 PMID:16152783 PMID:17035936 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873 		JBrowse link
G Ttr transthyretin increases expression ISO Puromycin Aminonucleoside results in increased expression of TTR protein CTD PMID:19264907 NCBI chr18:20,664,209...20,674,326
Ensembl chr18:20,665,280...20,674,321 		JBrowse link
G Ucp3 uncoupling protein 3 (mitochondrial, proton carrier) decreases expression EXP Puromycin Aminonucleoside results in decreased expression of UCP3 protein CTD PMID:19264907 NCBI chr 7:100,472,991...100,486,432
Ensembl chr 7:100,472,990...100,486,432 		JBrowse link
G Vcan versican decreases expression ISO Puromycin Aminonucleoside results in decreased expression of VCAN mRNA; Puromycin Aminonucleoside results in decreased expression of VCAN protein CTD PMID:15585670 NCBI chr13:89,655,309...89,743,027
Ensembl chr13:89,655,312...89,742,509 		JBrowse link
G Vcl vinculin affects localization
increases expression		 EXP
ISO		 Puromycin Aminonucleoside affects the localization of VCL protein
Puromycin Aminonucleoside results in increased expression of VCL mRNA; Puromycin Aminonucleoside results in increased expression of VCL protein		 CTD PMID:19617259 NCBI chr14:20,929,383...21,033,676
Ensembl chr14:20,929,398...21,033,676 		JBrowse link
G Vegfa vascular endothelial growth factor A affects expression
increases expression		 ISO Puromycin Aminonucleoside affects the expression of VEGFA mRNA
Puromycin Aminonucleoside results in increased expression of VEGFA protein		 CTD PMID:11744811 PMID:14752241 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369 		JBrowse link
G Vim vimentin multiple interactions
increases expression		 ISO fluvastatin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of VIM mRNA] CTD PMID:16452496 NCBI chr 2:13,574,311...13,582,826
Ensembl chr 2:13,573,927...13,582,826 		JBrowse link
G Wtip WT1-interacting protein affects localization EXP Puromycin Aminonucleoside affects the localization of WTIP protein CTD PMID:15798086 NCBI chr 7:34,109,547...34,133,268
Ensembl chr 7:34,109,543...34,133,268 		JBrowse link
G Xcl1 chemokine (C motif) ligand 1 affects expression ISO Puromycin Aminonucleoside affects the expression of XCL1 mRNA CTD PMID:10867541 NCBI chr 1:164,931,644...164,935,522
Ensembl chr 1:164,931,644...164,935,527 		JBrowse link
G Xdh xanthine dehydrogenase increases activity
multiple interactions		 ISO Puromycin Aminonucleoside results in increased activity of XDH
[Tungsten co-treated with Puromycin Aminonucleoside] results in decreased activity of XDH protein		 CTD PMID:7583048 PMID:11041286 NCBI chr17:73,883,895...73,950,397
Ensembl chr17:73,883,895...73,950,196 		JBrowse link
3'-phospho-5'-adenylyl sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nat2 N-acetyltransferase 2 (arylamine N-acetyltransferase) multiple interactions ISO [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone] CTD PMID:20545351 NCBI chr 8:67,494,875...67,502,644
Ensembl chr 8:67,494,858...67,502,584 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions ISO [NQO1 protein co-treated with NADP co-treated with Phosphoadenosine Phosphosulfate co-treated with SULT1A1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone CTD PMID:20545351 NCBI chr 8:107,388,225...107,403,205
Ensembl chr 8:107,388,225...107,403,206 		JBrowse link
G P2ry1 purinergic receptor P2Y, G-protein coupled 1 decreases activity ISO Phosphoadenosine Phosphosulfate results in decreased activity of P2RY1 protein CTD PMID:22273509 NCBI chr 3:61,002,785...61,008,982
Ensembl chr 3:61,002,795...61,008,982 		JBrowse link
G Sult1a1 sulfotransferase family 1A, phenol-preferring, member 1 multiple interactions ISO [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone] CTD PMID:20545351 NCBI chr 7:126,672,865...126,690,443
Ensembl chr 7:126,672,865...126,676,432 		JBrowse link
G Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 multiple interactions ISO [Phosphoadenosine Phosphosulfate co-treated with SULT2A1 protein] affects the sulfation of Ethinyl Estradiol; Celecoxib affects the reaction [[Phosphoadenosine Phosphosulfate co-treated with SULT2A1 protein] affects the sulfation of Ethinyl Estradiol]; SULT2A1 protein affects the metabolism of [Phosphoadenosine Phosphosulfate co-treated with Ethinyl Estradiol] CTD PMID:15483193 NCBI chr 7:13,796,246...13,837,410
Ensembl chr 7:13,796,246...13,837,409 		JBrowse link
3-iodobenzyl-5'-N-methylcarboxamidoadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora3 adenosine A3 receptor multiple interactions ISO
EXP		 2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA3 mRNA]]; 2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA3 protein]]; N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine binds to and results in increased activity of ADORA3 protein; N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA3 mRNA]; N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA3 protein]
[N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine binds to and results in increased activity of ADORA3 protein] which results in decreased susceptibility to Dizocilpine Maleate; [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine binds to and results in increased activity of ADORA3 protein] which results in decreased susceptibility to Scopolamine; N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine binds to and results in increased activity of ADORA3 protein		 CTD PMID:12672554 PMID:15452191 PMID:19966059 NCBI chr 3:105,904,421...105,908,928
Ensembl chr 3:105,870,858...105,908,926 		JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions ISO Pertussis Toxin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in increased phosphorylation of AKT1 protein]; wortmannin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in increased phosphorylation of AKT1 protein] CTD PMID:16116186 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression
decreases response to substance		 ISO N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of BIRC3 mRNA
BIRC3 protein results in decreased susceptibility to N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine		 CTD PMID:16088125 NCBI chr 9:7,847,468...7,873,205
Ensembl chr 9:7,848,699...7,873,186 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases response to substance ISO BIRC5 protein results in decreased susceptibility to N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine CTD PMID:16088125 NCBI chr11:117,849,237...117,855,743
Ensembl chr11:117,849,251...117,855,743 		JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions ISO N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of FOS mRNA] CTD PMID:15452191 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273 		JBrowse link
G Il12a interleukin 12a multiple interactions ISO N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]; Pertussis Toxin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]]; wortmannin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]] CTD PMID:16116186 NCBI chr 3:68,690,644...68,698,550
Ensembl chr 3:68,690,644...68,698,547 		JBrowse link
G Il12b interleukin 12b multiple interactions ISO N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]; Pertussis Toxin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]]; wortmannin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]] CTD PMID:16116186 NCBI chr11:44,400,063...44,414,677
Ensembl chr11:44,400,063...44,414,033 		JBrowse link
G Naip2 NLR family, apoptosis inhibitory protein 2 decreases response to substance
decreases expression		 ISO NAIP protein results in decreased susceptibility to N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine
N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of NAIP mRNA		 CTD PMID:16088125 NCBI chr13:100,144,063...100,202,122
Ensembl chr13:100,144,063...100,202,092 		JBrowse link
G Nppa natriuretic peptide type A multiple interactions ISO 2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]; N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA] CTD PMID:15452191 PMID:19966059 NCBI chr 4:148,000,722...148,002,074
Ensembl chr 4:148,000,722...148,002,079 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 multiple interactions ISO N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of RGS2 mRNA] CTD PMID:15452191 NCBI chr 1:143,999,338...144,004,149
Ensembl chr 1:143,999,338...144,004,161 		JBrowse link
G Slc9a1 solute carrier family 9 (sodium/hydrogen exchanger), member 1 multiple interactions ISO N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of SLC9A1 protein] CTD PMID:15452191 NCBI chr 4:133,369,711...133,423,702
Ensembl chr 4:133,369,706...133,423,702 		JBrowse link
5'-S-methyl-5'-thioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen, type I, alpha 1 decreases expression ISO 5'-methylthioadenosine results in decreased expression of COL1A1 mRNA CTD PMID:15983038 NCBI chr11:94,936,224...94,953,042
Ensembl chr11:94,936,224...94,953,042 		JBrowse link
G Col1a2 collagen, type I, alpha 2 decreases expression ISO 5'-methylthioadenosine results in decreased expression of COL1A2 mRNA CTD PMID:15983038 NCBI chr 6:4,505,618...4,541,543
Ensembl chr 6:4,504,814...4,541,544 		JBrowse link
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial multiple interactions
increases abundance		 EXP Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of 5'-methylthioadenosine] CTD PMID:27469509 NCBI chr 7:80,094,845...80,118,608
Ensembl chr 7:80,094,846...80,115,392 		JBrowse link
G Ifng interferon gamma multiple interactions EXP 5'-methylthioadenosine inhibits the reaction [fumonisin B1 results in increased expression of IFNG mRNA] CTD PMID:17080400 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP 5'-methylthioadenosine inhibits the reaction [fumonisin B1 results in increased expression of IL1B mRNA] CTD PMID:17080400 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139 		JBrowse link
G Il2 interleukin 2 multiple interactions EXP 5'-methylthioadenosine inhibits the reaction [fumonisin B1 results in increased expression of IL2 mRNA] CTD PMID:17080400 NCBI chr 3:37,120,713...37,125,954
Ensembl chr 3:37,120,523...37,125,959 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP 5'-methylthioadenosine inhibits the reaction [fumonisin B1 results in increased expression of IL6 mRNA] CTD PMID:17080400 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981 		JBrowse link
G Ltb lymphotoxin B multiple interactions EXP 5'-methylthioadenosine inhibits the reaction [fumonisin B1 results in increased expression of LTB mRNA] CTD PMID:17080400 NCBI chr17:35,194,507...35,196,305
Ensembl chr17:35,194,439...35,196,320 		JBrowse link
6-methylthioinosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc29a1 solute carrier family 29 (nucleoside transporters), member 1 affects transport ISO SLC29A1 mRNA affects the transport of Methylthioinosine CTD PMID:16859645 NCBI chr17:45,585,200...45,599,618
Ensembl chr17:45,585,200...45,599,606 		JBrowse link
7-methyl-GTP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif4e eukaryotic translation initiation factor 4E multiple interactions ISO 7-methylguanosine triphosphate inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein]; 7-methylguanosine triphosphate inhibits the reaction [RNA Caps binds to EIF4E protein] CTD PMID:27592390 NCBI chr 3:138,526,191...138,559,696
Ensembl chr 3:138,526,179...138,559,696 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
affects binding		 ISO 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one promotes the reaction [EIF4EBP1 protein binds to 7-methylguanosine triphosphate]; Sirolimus promotes the reaction [EIF4EBP1 protein binds to 7-methylguanosine triphosphate] CTD PMID:25940091 NCBI chr 8:27,260,327...27,275,656
Ensembl chr 8:27,260,329...27,276,674 		JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4, gamma 1 multiple interactions
affects binding		 ISO 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one inhibits the reaction [EIF4G1 protein binds to 7-methylguanosine triphosphate]; Sirolimus inhibits the reaction [EIF4G1 protein binds to 7-methylguanosine triphosphate] CTD PMID:25940091 NCBI chr16:20,672,720...20,692,883
Ensembl chr16:20,668,313...20,692,884 		JBrowse link
8,5'-cyclo-2'-deoxyadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neil1 nei endonuclease VIII-like 1 (E. coli) affects metabolic processing EXP NEIL1 protein affects the metabolism of 8,5'-cyclo-2'-deoxyadenosine CTD PMID:20067321 NCBI chr 9:57,142,788...57,148,688
Ensembl chr 9:57,142,800...57,148,305 		JBrowse link
8-chloro-2'-deoxyguanosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl5 chemokine (C-C motif) ligand 5 decreases expression EXP 8-chloro-2'-deoxyguanosine results in decreased expression of CCL5 mRNA CTD PMID:31066272 NCBI chr11:83,525,778...83,530,518
Ensembl chr11:83,525,778...83,530,518 		JBrowse link
G Il18 interleukin 18 increases expression EXP 8-chloro-2'-deoxyguanosine results in increased expression of IL18 mRNA CTD PMID:31066272 NCBI chr 9:50,554,700...50,581,841
Ensembl chr 9:50,554,827...50,581,840 		JBrowse link
G Il1b interleukin 1 beta increases secretion
increases expression		 EXP 8-chloro-2'-deoxyguanosine results in increased secretion of IL1B protein
8-chloro-2'-deoxyguanosine results in increased expression of IL1B mRNA		 CTD PMID:31066272 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139 		JBrowse link
8-hydroxy-2'-deoxyguanosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) increases abundance ISO AGT protein modified form results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine CTD PMID:30354818 NCBI chr 8:124,556,587...124,569,706
Ensembl chr 8:124,556,534...124,569,706 		JBrowse link
G Apex1 apurinic/apyrimidinic endonuclease 1 affects abundance ISO APEX1 gene SNP affects the abundance of 8-Hydroxy-2'-Deoxyguanosine CTD PMID:19896490 NCBI chr14:50,924,949...50,927,188
Ensembl chr14:50,924,968...50,927,139 		JBrowse link
G Brca1 breast cancer 1, early onset multiple interactions EXP [BRCA1 gene mutant form results in increased susceptibility to Ethanol] which results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine CTD PMID:26629949 NCBI chr11:101,488,761...101,551,955
Ensembl chr11:101,488,764...101,551,955 		JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 multiple interactions ISO [Eugenol co-treated with Copper co-treated with CYP2D6 protein] results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine CTD PMID:15576237 NCBI chr15:82,370,527...82,380,260
Ensembl chr15:82,370,527...82,380,260 		JBrowse link
G Dnmt1 DNA methyltransferase (cytosine-5) 1 affects abundance ISO DNMT1 gene SNP affects the abundance of 8-Hydroxy-2'-Deoxyguanosine CTD PMID:19896490 NCBI chr 9:20,907,206...20,959,888
Ensembl chr 9:20,907,209...20,959,888 		JBrowse link
G Dnmt3b DNA methyltransferase 3B affects abundance ISO DNMT3B gene SNP affects the abundance of 8-Hydroxy-2'-Deoxyguanosine CTD PMID:19896490 NCBI chr 2:153,649,411...153,687,730
Ensembl chr 2:153,649,450...153,687,730 		JBrowse link
G Glrx glutaredoxin affects abundance ISO GLRX gene SNP affects the abundance of 8-Hydroxy-2'-Deoxyguanosine CTD PMID:19896490 NCBI chr13:75,839,885...75,850,151
Ensembl chr13:75,839,868...75,850,154 		JBrowse link
G Hras Harvey rat sarcoma virus oncogene multiple interactions
increases abundance		 EXP PRDX1 protein inhibits the reaction [HRAS protein mutant form results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine] CTD PMID:27517622 NCBI chr 7:141,189,934...141,194,019
Ensembl chr 7:141,189,105...141,194,005 		JBrowse link
G Ogg1 8-oxoguanine DNA-glycosylase 1 increases cleavage
multiple interactions		 ISO OGG1 protein results in increased cleavage of 8-Hydroxy-2'-Deoxyguanosine
thymidine glycol inhibits the reaction [OGG1 protein results in increased cleavage of 8-Hydroxy-2'-Deoxyguanosine]; thymidine glycol promotes the reaction [OGG1 protein results in increased cleavage of 8-Hydroxy-2'-Deoxyguanosine]		 CTD PMID:19193190 NCBI chr 6:113,326,972...113,334,877
Ensembl chr 6:113,326,972...113,335,068 		JBrowse link
G Por P450 (cytochrome) oxidoreductase multiple interactions ISO [Nitrofurazone co-treated with POR protein co-treated with Copper] results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine CTD PMID:15488632 NCBI chr 5:135,670,040...135,735,326
Ensembl chr 5:135,670,033...135,735,326 		JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions EXP PRDX1 protein inhibits the reaction [HRAS protein mutant form results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine] CTD PMID:27517622 NCBI chr 4:116,685,599...116,700,000
Ensembl chr 4:116,685,544...116,700,822 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO [[Arachidonic Acid results in increased activity of PTGS1 protein] which results in increased susceptibility to 3,4-Methylenedioxyamphetamine] which results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine; [[Arachidonic Acid results in increased activity of PTGS1 protein] which results in increased susceptibility to Methamphetamine] which results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine CTD PMID:21163909 NCBI chr 2:36,216,742...36,258,593
Ensembl chr 2:36,230,426...36,252,272 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [[Arachidonic Acid results in increased activity of PTGS2 protein] which results in increased susceptibility to 3,4-Methylenedioxyamphetamine] which results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine; [[Arachidonic Acid results in increased activity of PTGS2 protein] which results in increased susceptibility to Methamphetamine] which results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine CTD PMID:21163909 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227 		JBrowse link
G Txnrd1 thioredoxin reductase 1 affects abundance ISO TXNRD1 gene SNP affects the abundance of 8-Hydroxy-2'-Deoxyguanosine CTD PMID:19896490 NCBI chr10:82,833,951...82,897,724
Ensembl chr10:82,833,951...82,897,712 		JBrowse link
G Txnrd2 thioredoxin reductase 2 affects abundance ISO TXNRD2 gene SNP affects the abundance of 8-Hydroxy-2'-Deoxyguanosine CTD PMID:19896490 NCBI chr16:18,426,417...18,479,073
Ensembl chr16:18,426,384...18,479,073 		JBrowse link
8-Hydroxyguanosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egf epidermal growth factor increases abundance
multiple interactions		 ISO EGF protein results in increased abundance of 8-hydroxyguanosine
Acetylcysteine inhibits the reaction [EGF protein results in increased abundance of 8-hydroxyguanosine]; Selenium inhibits the reaction [EGF protein results in increased abundance of 8-hydroxyguanosine]		 CTD PMID:11158190 NCBI chr 3:129,677,574...129,755,322
Ensembl chr 3:129,677,565...129,755,316 		JBrowse link
acetoacetyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 affects binding ISO acetoacetyl CoA binds to HSD17B2 protein CTD PMID:25526675 NCBI chr 8:117,700,982...117,759,030
Ensembl chr 8:117,701,904...117,759,027 		JBrowse link
acetyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acly ATP citrate lyase increases abundance EXP ACLY protein results in increased abundance of Acetyl Coenzyme A CTD PMID:28077572 NCBI chr11:100,476,352...100,528,000
Ensembl chr11:100,476,353...100,528,000 		JBrowse link
G App amyloid beta (A4) precursor protein affects localization
increases secretion
multiple interactions		 EXP
ISO		 APP protein affects the localization of Acetyl Coenzyme A
Acetyl Coenzyme A results in increased secretion of APP protein modified form
Acetyl Coenzyme A inhibits the reaction [Hydrogen Peroxide results in decreased secretion of APP protein modified form]
IL1B protein affects the reaction [APP protein affects the localization of Acetyl Coenzyme A]		 CTD PMID:16122837 PMID:22906069 NCBI chr16:84,952,666...85,175,255
Ensembl chr16:84,949,685...85,173,766 		JBrowse link
G Crat carnitine acetyltransferase decreases activity ISO Acetyl Coenzyme A deficiency results in decreased activity of CRAT protein CTD PMID:8075222 NCBI chr 2:30,400,476...30,416,017
Ensembl chr 2:30,400,471...30,415,813 		JBrowse link
G Ercc6 excision repair cross-complementing rodent repair deficiency, complementation group 6 decreases abundance
multiple interactions		 ISO ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A
3-Hydroxybutyric Acid inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A]		 CTD PMID:25440059 NCBI chr14:32,513,291...32,580,990
Ensembl chr14:32,513,521...32,580,990 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP IL1B protein affects the reaction [APP protein affects the localization of Acetyl Coenzyme A] CTD PMID:16122837 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139 		JBrowse link
G Kat2b K(lysine) acetyltransferase 2B affects binding EXP Acetyl Coenzyme A binds to KAT2B protein CTD PMID:28077572 NCBI chr17:53,566,774...53,672,721
Ensembl chr17:53,566,861...53,672,720 		JBrowse link
G Metrnl meteorin, glial cell differentiation regulator-like multiple interactions EXP METRNL protein inhibits the reaction [Dietary Fats results in decreased abundance of Acetyl Coenzyme A] CTD PMID:30213948 NCBI chr11:121,702,427...121,717,389
Ensembl chr11:121,701,544...121,716,306 		JBrowse link
G Nat1 N-acetyl transferase 1 multiple interactions
affects binding		 ISO [NQO1 protein co-treated with NADP co-treated with Acetyl Coenzyme A co-treated with NAT1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone; Acetyl Coenzyme A inhibits the reaction [Cyanamide results in decreased activity of NAT1 protein]; Acetyl Coenzyme A inhibits the reaction [Iodoacetamide results in decreased activity of NAT1 protein]
Acetyl Coenzyme A binds to NAT1 protein		 CTD PMID:20545351 PMID:22835378 NCBI chr 8:67,490,968...67,492,531
Ensembl chr 8:67,480,921...67,492,104 		JBrowse link
G Nat2 N-acetyltransferase 2 (arylamine N-acetyltransferase) multiple interactions ISO [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]; [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone] CTD PMID:20545351 NCBI chr 8:67,494,875...67,502,644
Ensembl chr 8:67,494,858...67,502,584 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions ISO [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]; [NQO1 protein co-treated with NADP co-treated with Acetyl Coenzyme A co-treated with NAT1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone CTD PMID:20545351 NCBI chr 8:107,388,225...107,403,205
Ensembl chr 8:107,388,225...107,403,206 		JBrowse link
G Sult1a1 sulfotransferase family 1A, phenol-preferring, member 1 multiple interactions ISO [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone] CTD PMID:20545351 NCBI chr 7:126,672,865...126,690,443
Ensembl chr 7:126,672,865...126,676,432 		JBrowse link
acryloyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Echs1 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial increases abundance ISO ECHS1 gene mutant form results in increased abundance of acryloyl-coenzyme A CTD PMID:25125611 NCBI chr 7:140,105,710...140,116,421
Ensembl chr 7:140,105,710...140,116,476 		JBrowse link
G Hibch 3-hydroxyisobutyryl-Coenzyme A hydrolase increases abundance ISO HIBCH gene mutant form results in increased abundance of acryloyl-coenzyme A CTD PMID:25125611 NCBI chr 1:52,845,038...52,920,986
Ensembl chr 1:52,844,929...52,920,986 		JBrowse link
adenine arabinoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Vidarabine results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr16:38,248,349...38,294,849
Ensembl chr16:38,248,323...38,294,824 		JBrowse link
adenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase decreases metabolic processing
increases metabolic processing		 ISO ADA alternative form results in decreased metabolism of Adenosine
ADA protein results in increased metabolism of Adenosine		 CTD PMID:16221767 NCBI chr 2:163,726,571...163,750,239
Ensembl chr 2:163,726,584...163,750,239 		JBrowse link
G Adora1 adenosine A1 receptor multiple interactions
affects binding		 ISO Adenosine analog binds to and affects the activity of ADORA1 protein; Adenosine analog binds to and results in decreased activity of ADORA1 protein; PD 81723 affects the reaction [Adenosine analog binds to and affects the activity of ADORA1 protein]; VUF 5455 affects the reaction [Adenosine analog binds to and affects the activity of ADORA1 protein]
[lead acetate results in increased expression of ADORA1 protein] which results in increased abundance of Adenosine; Adenosine analog binds to and results in increased activity of ADORA1 protein
Adenosine binds to ADORA1 protein		 CTD PMID:10649980 PMID:11520205 PMID:18404447 PMID:20571079 PMID:20932874 NCBI chr 1:134,199,215...134,235,457
Ensembl chr 1:134,199,223...134,235,431 		JBrowse link
G Adora2a adenosine A2a receptor multiple interactions
affects binding		 ISO Adenosine analog binds to and results in decreased activity of ADORA2A protein; Adenosine promotes the reaction [Lipopolysaccharides results in increased expression of ADORA2A mRNA]
Adenosine binds to ADORA2A protein		 CTD PMID:18404447 PMID:20067761 NCBI chr10:75,316,877...75,334,792
Ensembl chr10:75,316,877...75,334,784 		JBrowse link
G Adora2b adenosine A2b receptor affects response to substance EXP ADORA2B protein affects the susceptibility to Adenosine CTD PMID:16920807 NCBI chr11:62,248,984...62,266,452
Ensembl chr11:62,248,984...62,266,453 		JBrowse link
G Adora3 adenosine A3 receptor multiple interactions
affects binding
increases expression		 ISO Adenosine analog binds to and affects the activity of ADORA3 protein; Adenosine analog binds to and results in decreased activity of ADORA3 protein; Adenosine analog binds to and results in increased activity of ADORA3 protein; PD 81723 affects the reaction [Adenosine analog binds to and affects the activity of ADORA3 protein]; VUF 5455 affects the reaction [Adenosine analog binds to and affects the activity of ADORA3 protein]
Adenosine binds to ADORA3 protein
Adenosine results in increased expression of ADORA3 mRNA		 CTD PMID:11520205 PMID:18404447 PMID:20067761 PMID:20571079 NCBI chr 3:105,904,421...105,908,928
Ensembl chr 3:105,870,858...105,908,926 		JBrowse link
G Alpi alkaline phosphatase, intestinal multiple interactions ISO Adenosine inhibits the reaction [Methotrexate results in increased activity of ALPI protein] CTD PMID:16598758 NCBI chr 1:87,098,002...87,101,606
Ensembl chr 1:87,098,002...87,101,606 		JBrowse link
G Ampd2 adenosine monophosphate deaminase 2 multiple interactions ISO [tofacitinib results in decreased expression of AMPD2 protein] which affects the abundance of Adenosine CTD PMID:25496463 NCBI chr 3:108,074,059...108,086,687
Ensembl chr 3:108,074,062...108,086,651 		JBrowse link
G Bax BCL2-associated X protein increases localization
multiple interactions		 ISO Adenosine results in increased localization of BAX protein
Thymidine inhibits the reaction [Adenosine results in increased localization of BAX protein]		 CTD PMID:11570579 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898 		JBrowse link
G Bcl2l1 BCL2-like 1 decreases expression
multiple interactions		 ISO Adenosine results in decreased expression of BCL2L1 mRNA; Adenosine results in decreased expression of BCL2L1 protein
Dipyridamole inhibits the reaction [Adenosine results in decreased expression of BCL2L1 mRNA]; Dipyridamole inhibits the reaction [Adenosine results in decreased expression of BCL2L1 protein]		 CTD PMID:20063052 NCBI chr 2:152,758,732...152,833,803
Ensembl chr 2:152,780,668...152,831,728 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO Adenosine results in decreased expression of BIRC2 mRNA; Adenosine results in decreased expression of BIRC2 protein CTD PMID:20063052 NCBI chr 9:7,818,226...7,837,131
Ensembl chr 9:7,818,227...7,837,064 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO Adenosine results in decreased expression of BIRC3 mRNA CTD PMID:20063052 NCBI chr 9:7,847,468...7,873,205
Ensembl chr 9:7,848,699...7,873,186 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity		 ISO Dipyridamole inhibits the reaction [Adenosine results in increased activity of CASP3 protein]; Thymidine inhibits the reaction [Adenosine results in increased activity of CASP3 protein] CTD PMID:11570579 PMID:16469385 PMID:17303086 PMID:20063052 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689 		JBrowse link
G Casp8 caspase 8 increases activity
multiple interactions		 ISO Adenosine results in increased activity of CASP8 protein
Dipyridamole inhibits the reaction [Adenosine results in increased activity of CASP8 protein]		 CTD PMID:16469385 PMID:17303086 NCBI chr 1:58,795,233...58,847,503
Ensembl chr 1:58,795,374...58,847,503 		JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions		 ISO Adenosine results in increased activity of CASP9 protein
Thymidine inhibits the reaction [Adenosine results in increased activity of CASP9 protein]		 CTD PMID:11570579 PMID:16469385 NCBI chr 4:141,793,612...141,815,978
Ensembl chr 4:141,793,612...141,815,976 		JBrowse link
G Cd14 CD14 antigen increases expression ISO Adenosine results in increased expression of CD14 mRNA CTD PMID:21538184 NCBI chr18:36,725,064...36,726,815
Ensembl chr18:36,725,067...36,726,798 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression
multiple interactions		 ISO Adenosine results in decreased expression of CFLAR mRNA; Adenosine results in decreased expression of CFLAR mRNA alternative form; Adenosine results in decreased expression of CFLAR protein
Dipyridamole inhibits the reaction [Adenosine results in decreased expression of CFLAR mRNA alternative form]; Dipyridamole inhibits the reaction [Adenosine results in decreased expression of CFLAR mRNA]; Dipyridamole inhibits the reaction [Adenosine results in decreased expression of CFLAR protein]		 CTD PMID:17303086 NCBI chr 1:58,711,311...58,758,884
Ensembl chr 1:58,711,508...58,758,884 		JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator increases activity
multiple interactions		 ISO Adenosine results in increased activity of CFTR protein
[Isoproterenol co-treated with Adenosine] results in increased activity of CFTR protein		 CTD PMID:15039139 NCBI chr 6:18,170,687...18,322,770
Ensembl chr 6:18,170,687...18,322,768 		JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 multiple interactions ISO [Adenosine co-treated with Homocysteine] inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; [Adenosine co-treated with Homocysteine] results in decreased expression of CXCL8 mRNA CTD PMID:24224954 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein increases expression
multiple interactions		 ISO Adenosine results in increased expression of DIABLO mRNA; Adenosine results in increased expression of DIABLO protein
Dipyridamole inhibits the reaction [Adenosine results in increased expression of DIABLO mRNA]; Dipyridamole inhibits the reaction [Adenosine results in increased expression of DIABLO protein]		 CTD PMID:20063052 NCBI chr 5:123,511,330...123,524,164
Ensembl chr 5:123,509,765...123,524,176 		JBrowse link
G Dpp4 dipeptidylpeptidase 4 decreases expression
multiple interactions		 ISO Adenosine results in decreased expression of DPP4 mRNA; Adenosine results in decreased expression of DPP4 protein
[Adenosine results in decreased phosphorylation of MAPK1 protein] which results in decreased expression of DPP4 mRNA; [Adenosine results in decreased phosphorylation of MAPK1 protein] which results in decreased expression of DPP4 protein; [Adenosine results in decreased phosphorylation of MAPK3 protein] which results in decreased expression of DPP4 mRNA; [Adenosine results in decreased phosphorylation of MAPK3 protein] which results in decreased expression of DPP4 protein		 CTD PMID:16611738 NCBI chr 2:62,330,073...62,412,315
Ensembl chr 2:62,330,073...62,412,231 		JBrowse link
G Fadd Fas (TNFRSF6)-associated via death domain decreases expression
multiple interactions		 ISO Adenosine results in decreased expression of FADD mRNA
Dipyridamole inhibits the reaction [Adenosine results in decreased expression of FADD mRNA]		 CTD PMID:17303086 NCBI chr 7:144,578,323...144,582,441
Ensembl chr 7:144,577,318...144,582,463 		JBrowse link
G Fasl Fas ligand (TNF superfamily, member 6) increases expression
multiple interactions		 ISO
EXP		 Adenosine results in increased expression of FASLG protein
[Adenosine co-treated with Coformycin] results in decreased expression of FASL mRNA		 CTD PMID:11992407 PMID:16419169 NCBI chr 1:161,780,691...161,788,495
Ensembl chr 1:161,780,689...161,788,495 		JBrowse link
G Gzmb granzyme B multiple interactions EXP [Adenosine co-treated with Coformycin] results in decreased expression of GZMB mRNA CTD PMID:11992407 NCBI chr14:56,258,836...56,262,334
Ensembl chr14:56,258,838...56,262,260 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit increases expression ISO Adenosine results in increased expression of HIF1A mRNA CTD PMID:20067761 NCBI chr12:73,901,324...73,947,554
Ensembl chr12:73,901,375...73,947,530 		JBrowse link
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial multiple interactions
increases abundance		 EXP Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Adenosine] CTD PMID:27469509 NCBI chr 7:80,094,845...80,118,608
Ensembl chr 7:80,094,846...80,115,392 		JBrowse link
G Ifng interferon gamma multiple interactions EXP [Adenosine co-treated with Coformycin] results in decreased expression of IFNG protein CTD PMID:11992407 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892 		JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression		 EXP Adenosine promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]
Adenosine results in increased expression of IL10 mRNA; Adenosine results in increased expression of IL10 protein		 CTD PMID:11023991 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974 		JBrowse link
G Il12b interleukin 12b decreases expression
multiple interactions		 EXP Adenosine results in decreased expression of IL12B protein
Adenosine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]		 CTD PMID:11023991 NCBI chr11:44,400,063...44,414,677
Ensembl chr11:44,400,063...44,414,033 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Adenosine inhibits the reaction [IL1B protein results in increased abundance of Nitric Oxide]; Adenosine inhibits the reaction [IL1B protein results in increased expression of IL1R1]; Adenosine inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; Adenosine inhibits the reaction [IL1B protein results in increased expression of NOS2 protein] CTD PMID:24878381 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139 		JBrowse link
G Il1r1 interleukin 1 receptor, type I multiple interactions ISO Adenosine inhibits the reaction [IL1B protein results in increased expression of IL1R1] CTD PMID:24878381 NCBI chr 1:40,222,480...40,316,201
Ensembl chr 1:40,225,080...40,317,257 		JBrowse link
G Il2 interleukin 2 multiple interactions EXP [Adenosine co-treated with Coformycin] results in decreased expression of IL2 protein CTD PMID:11992407 NCBI chr 3:37,120,713...37,125,954
Ensembl chr 3:37,120,523...37,125,959 		JBrowse link
G Ly96 lymphocyte antigen 96 increases expression ISO Adenosine results in increased expression of LY96 mRNA CTD PMID:21538184 NCBI chr 1:16,688,456...16,709,605
Ensembl chr 1:16,688,051...16,709,611 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
decreases phosphorylation		 ISO [Adenosine results in decreased phosphorylation of MAPK1 protein] which results in decreased expression of DPP4 mRNA; [Adenosine results in decreased phosphorylation of MAPK1 protein] which results in decreased expression of DPP4 protein CTD PMID:16611738 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 decreases phosphorylation
multiple interactions		 ISO Adenosine results in decreased phosphorylation of MAPK3 protein
[Adenosine results in decreased phosphorylation of MAPK3 protein] which results in decreased expression of DPP4 mRNA; [Adenosine results in decreased phosphorylation of MAPK3 protein] which results in decreased expression of DPP4 protein		 CTD PMID:16611738 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819 		JBrowse link
G Myc myelocytomatosis oncogene decreases expression
multiple interactions		 ISO Adenosine results in decreased expression of MYC protein
Thymidine inhibits the reaction [Adenosine results in decreased expression of MYC protein]; Uridine inhibits the reaction [Adenosine results in decreased expression of MYC protein]		 CTD PMID:9808420 NCBI chr15:61,985,341...61,990,361
Ensembl chr15:61,985,391...61,990,374 		JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions ISO [Adenosine co-treated with Homocysteine] affects the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]; [Adenosine co-treated with Homocysteine] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; [Adenosine co-treated with Homocysteine] results in decreased expression of NFKBIA mRNA CTD PMID:24224954 NCBI chr12:55,489,409...55,492,647
Ensembl chr12:55,489,410...55,492,647 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible decreases stability
multiple interactions		 ISO Adenosine results in decreased stability of NOS2 mRNA
Adenosine inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; Adenosine inhibits the reaction [IL1B protein results in increased expression of NOS2 protein]		 CTD PMID:24878381 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254 		JBrowse link
G Nt5e 5' nucleotidase, ecto multiple interactions EXP [alpha,beta-methyleneadenosine 5'-diphosphate results in decreased activity of NT5E protein] inhibits the reaction [Oxygen deficiency results in increased abundance of Adenosine] CTD PMID:23437309 NCBI chr 9:88,327,609...88,372,089
Ensembl chr 9:88,327,197...88,372,092 		JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha increases expression ISO Adenosine results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr 5:51,454,249...52,115,853
Ensembl chr 5:51,454,250...51,567,726 		JBrowse link
G Prf1 perforin 1 (pore forming protein) multiple interactions EXP [Adenosine co-treated with Coformycin] results in decreased expression of PRF1 mRNA CTD PMID:11992407 NCBI chr10:61,297,751...61,304,684
Ensembl chr10:61,297,833...61,304,680 		JBrowse link
G Ptgdr prostaglandin D receptor multiple interactions EXP [Prostaglandin D2 results in increased activity of PTGDR protein] which results in increased metabolism of Adenosine; [Prostaglandin D2 results in increased activity of PTGDR protein] which results in increased secretion of Adenosine CTD PMID:11562489 NCBI chr14:44,851,235...44,859,375
Ensembl chr14:44,851,235...44,859,375 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO [Adenosine co-treated with Homocysteine] affects the reaction [TNF protein affects the localization of RELA protein modified form]; [Adenosine co-treated with Homocysteine] affects the reaction [TNF protein results in increased phosphorylation of RELA protein] CTD PMID:24224954 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130 		JBrowse link
G Ren1 renin 1 structural decreases secretion ISO Adenosine results in decreased secretion of REN protein CTD PMID:3044993 NCBI chr 1:133,350,674...133,360,320
Ensembl chr 1:133,350,510...133,360,325 		JBrowse link
G Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 multiple interactions ISO [Adenosine co-treated with Homocysteine co-treated with TNF protein] results in increased cleavage of RIPK1 protein CTD PMID:24224954 NCBI chr13:34,002,225...34,035,170
Ensembl chr13:34,002,363...34,037,147 		JBrowse link
G Slc28a1 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 affects transport
multiple interactions		 ISO SLC28A1 protein affects the transport of Adenosine
Adenosine inhibits the reaction [SLC28A1 protein results in increased uptake of Uridine]		 CTD PMID:9124315 NCBI chr 7:81,113,269...81,170,416
Ensembl chr 7:81,114,799...81,170,416 		JBrowse link
G Slc28a2 solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 increases transport ISO SLC28A2 protein results in increased transport of Adenosine CTD PMID:10087507 NCBI chr 2:122,426,357...122,461,152
Ensembl chr 2:122,426,477...122,461,137 		JBrowse link
G Slc29a1 solute carrier family 29 (nucleoside transporters), member 1 multiple interactions
increases uptake
affects abundance		 EXP
ISO		 4-nitrobenzylthioinosine inhibits the reaction [SLC29A1 protein alternative form results in increased uptake of Adenosine]; 4-nitrobenzylthioinosine inhibits the reaction [SLC29A1 protein results in increased uptake of Adenosine]; [4-nitrobenzylthioinosine results in decreased activity of SLC29A1 protein] inhibits the reaction [Oxygen deficiency results in increased abundance of Adenosine]; [SLC29A1 co-treated with Oxygen deficiency] affects the abundance of Adenosine; Dipyridamole inhibits the reaction [SLC29A1 protein alternative form results in increased uptake of Adenosine]; Dipyridamole inhibits the reaction [SLC29A1 protein results in increased uptake of Adenosine]; Dipyridamole promotes the reaction [[SLC29A1 co-treated with Oxygen deficiency] affects the abundance of Adenosine]
SLC29A1 protein alternative form results in increased uptake of Adenosine; SLC29A1 protein results in increased uptake of Adenosine
cilostazol inhibits the reaction [SLC29A1 protein results in increased uptake of Adenosine]; Dipyridamole inhibits the reaction [SLC29A1 protein results in increased uptake of Adenosine]; draflazine inhibits the reaction [SLC29A1 protein results in increased uptake of Adenosine]; Ethanol promotes the reaction [SLC29A1 protein alternative form results in increased uptake of Adenosine]; Ethanol promotes the reaction [SLC29A1 protein results in increased uptake of Adenosine]; Ticagrelor inhibits the reaction [SLC29A1 protein results in increased uptake of Adenosine]
Adenosine inhibits the reaction [SLC29A1 protein results in increased uptake of Uridine]
SLC29A1 affects the abundance of Adenosine		 CTD PMID:9353301 PMID:9396714 PMID:11179696 PMID:21283641 PMID:21872611 PMID:23437309 PMID:28041785 NCBI chr17:45,585,200...45,599,618
Ensembl chr17:45,585,200...45,599,606 		JBrowse link
G Slc29a2 solute carrier family 29 (nucleoside transporters), member 2 increases uptake ISO SLC29A2 protein results in increased uptake of Adenosine CTD PMID:9396714 NCBI chr19:5,019,057...5,031,972
Ensembl chr19:5,023,860...5,031,972 		JBrowse link
G Slc29a3 solute carrier family 29 (nucleoside transporters), member 3 affects transport ISO SLC29A3 protein affects the transport of Adenosine CTD PMID:19164483 NCBI chr10:60,712,072...60,752,849
Ensembl chr10:60,712,072...60,752,794 		JBrowse link
G Slc5a5 solute carrier family 5 (sodium iodide symporter), member 5 increases expression ISO Adenosine results in increased expression of SLC5A5 mRNA; Adenosine results in increased expression of SLC5A5 protein CTD PMID:16954431 NCBI chr 8:70,882,885...70,892,785
Ensembl chr 8:70,882,889...70,892,757 		JBrowse link
G Tlr4 toll-like receptor 4 increases expression
affects localization
multiple interactions		 ISO Adenosine results in increased expression of TLR4 mRNA
Adenosine affects the localization of TLR4 protein
Adenosine promotes the reaction [lipopolysaccharide, E. coli O26-B6 affects the localization of TLR4 protein]		 CTD PMID:21538184 NCBI chr 4:66,827,551...66,846,581
Ensembl chr 4:66,827,584...66,930,284 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression		 ISO
EXP		 5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine inhibits the reaction [Adenosine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of TNF protein]]; [Adenosine co-treated with Homocysteine co-treated with TNF protein] results in increased cleavage of RIPK1 protein; [Adenosine co-treated with Homocysteine] affects the reaction [TNF protein affects the localization of RELA protein modified form]; [Adenosine co-treated with Homocysteine] affects the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]; [Adenosine co-treated with Homocysteine] affects the reaction [TNF protein results in increased phosphorylation of RELA protein]; [Adenosine co-treated with Homocysteine] inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; [Adenosine co-treated with Homocysteine] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; [Adenosine co-treated with Homocysteine] inhibits the reaction [TNF protein results in increased expression of TNFAIP3 mRNA]; [Adenosine co-treated with Homocysteine] inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]; [Adenosine co-treated with Homocysteine] results in increased susceptibility to TNF protein; Adenosine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF mRNA]; Adenosine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of TNF protein]; ZM 241385 inhibits the reaction [Adenosine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of TNF protein]]
Adenosine results in decreased expression of TNF protein		 CTD PMID:11023991 PMID:21538184 PMID:24224954 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007 		JBrowse link
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 multiple interactions ISO [Adenosine co-treated with Homocysteine] inhibits the reaction [TNF protein results in increased expression of TNFAIP3 mRNA]; [Adenosine co-treated with Homocysteine] inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]; [Adenosine co-treated with Homocysteine] results in decreased expression of TNFAIP3 mRNA; [Adenosine co-treated with Homocysteine] results in decreased expression of TNFAIP3 protein CTD PMID:24224954 NCBI chr10:19,000,910...19,015,410
Ensembl chr10:19,000,910...19,015,657 		JBrowse link
G Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 multiple interactions EXP [Adenosine co-treated with Coformycin] results in decreased expression of TNFSF10 mRNA CTD PMID:11992407 NCBI chr 3:27,317,077...27,339,665
Ensembl chr 3:27,317,028...27,342,427 		JBrowse link
G Upp1 uridine phosphorylase 1 increases metabolic processing EXP UPP1 protein results in increased metabolism of Adenosine CTD PMID:15772079 NCBI chr11:9,118,008...9,136,170
Ensembl chr11:9,118,103...9,136,170 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases expression
increases secretion		 ISO Adenosine promotes the reaction [Dipyridamole results in increased secretion of VEGFA protein]
Adenosine results in increased expression of VEGFA mRNA
Adenosine results in increased secretion of VEGFA protein		 CTD PMID:20067761 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369 		JBrowse link
adenosine 3',5'-bismonophosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sult1a1 sulfotransferase family 1A, phenol-preferring, member 1 multiple interactions ISO Glutathione Disulfide affects the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT1A1 protein]; Glutathione Disulfide affects the reaction [Polychlorinated Biphenyls analog affects the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT1A1 protein]]; Polychlorinated Biphenyls analog affects the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT1A1 protein] CTD PMID:21130751 NCBI chr 7:126,672,865...126,690,443
Ensembl chr 7:126,672,865...126,676,432 		JBrowse link
G Sult1e1 sulfotransferase family 1E, member 1 multiple interactions ISO [2,2',4,4'-tetrabromodiphenyl ether metabolite co-treated with adenosine 3'-phosphate-5'-phosphate] binds to SULT1E1 protein; [Estradiol co-treated with adenosine 3'-phosphate-5'-phosphate] binds to SULT1E1 protein; [tetrabromobisphenol A co-treated with adenosine 3'-phosphate-5'-phosphate] binds to SULT1E1 protein; Estradiol inhibits the reaction [[tetrabromobisphenol A co-treated with adenosine 3'-phosphate-5'-phosphate] binds to SULT1E1 protein]; tetrabromobisphenol A inhibits the reaction [[Estradiol co-treated with adenosine 3'-phosphate-5'-phosphate] binds to SULT1E1 protein] CTD PMID:23959441 NCBI chr 5:87,575,968...87,591,611
Ensembl chr 5:87,575,969...87,591,594 		JBrowse link
G Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 affects binding
multiple interactions		 ISO adenosine 3'-phosphate-5'-phosphate binds to SULT2A1 protein
Benzoquinones analog inhibits the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT2A1 protein]; Dehydroepiandrosterone inhibits the reaction [Benzoquinones analog inhibits the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT2A1 protein]]		 CTD PMID:24059442 NCBI chr 7:13,796,246...13,837,410
Ensembl chr 7:13,796,246...13,837,409 		JBrowse link
adenosine 5'-(hexahydrogen pentaphosphate) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt10 nudix (nucleoside diphosphate linked moiety X)-type motif 10 multiple interactions ISO [NUDT11 protein results in increased metabolism of diadenosine 5',5''''-P1,P6-hexaphosphate] which results in increased chemical synthesis of adenosine 5'-pentaphosphate CTD PMID:12121577 NCBI chr  X:6,168,696...6,173,009
Ensembl chr  X:6,168,696...6,173,015
Ensembl chr  X:6,168,696...6,173,015 		JBrowse link
adenosine 5'-[gamma-thio]triphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd80 CD80 antigen increases expression EXP adenosine 5'-O-(3-thiotriphosphate) results in increased expression of CD80 protein CTD PMID:15944274 NCBI chr16:38,457,430...38,495,958
Ensembl chr16:38,455,561...38,496,335 		JBrowse link
G Cd86 CD86 antigen increases expression EXP adenosine 5'-O-(3-thiotriphosphate) results in increased expression of CD86 protein CTD PMID:15944274 NCBI chr16:36,568,956...36,666,158
Ensembl chr16:36,603,869...36,666,081 		JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 multiple interactions ISO [adenosine 5'-O-(3-thiotriphosphate) binds to and results in increased activity of P2RY11 protein] which results in increased expression of CXCL8 protein CTD PMID:19815812 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067 		JBrowse link
G Il10 interleukin 10 decreases expression EXP adenosine 5'-O-(3-thiotriphosphate) results in decreased expression of IL10 protein CTD PMID:15944274 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974 		JBrowse link
G Il12b interleukin 12b increases expression EXP adenosine 5'-O-(3-thiotriphosphate) results in increased expression of IL12B protein CTD PMID:15944274 NCBI chr11:44,400,063...44,414,677
Ensembl chr11:44,400,063...44,414,033 		JBrowse link
G Il1b interleukin 1 beta increases expression EXP adenosine 5'-O-(3-thiotriphosphate) results in increased expression of IL1B protein CTD PMID:15944274 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139 		JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 affects response to substance EXP P2RX7 protein affects the susceptibility to adenosine 5'-O-(3-thiotriphosphate) CTD PMID:12873706 NCBI chr 5:122,643,927...122,692,336
Ensembl chr 5:122,643,911...122,691,432 		JBrowse link
G Ptgdr prostaglandin D receptor multiple interactions ISO adenosine 5'-O-(3-thiotriphosphate) inhibits the reaction [Prostaglandin D2 binds to PTGDR protein] CTD PMID:9579725 NCBI chr14:44,851,235...44,859,375
Ensembl chr14:44,851,235...44,859,375 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 increases activity
multiple interactions		 ISO adenosine 5'-O-(3-thiotriphosphate) results in increased activity of TRPV1 protein
Capsaicin promotes the reaction [adenosine 5'-O-(3-thiotriphosphate) results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [adenosine 5'-O-(3-thiotriphosphate) results in increased activity of TRPV1 protein]		 CTD PMID:11140687 NCBI chr11:73,234,149...73,261,322
Ensembl chr11:73,234,292...73,261,242 		JBrowse link
adenosine 5'-monophosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 multiple interactions EXP Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]; Creatine metabolite inhibits the reaction [Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]] CTD PMID:11390963 NCBI chr 6:142,587,862...142,702,766
Ensembl chr 6:142,587,862...142,702,315 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 multiple interactions ISO [4-dimethylaminocinnamaldehyde co-treated with Adenosine Monophosphate] binds to ALDH1A1 protein CTD PMID:10609638 NCBI chr19:20,492,583...20,643,463
Ensembl chr19:20,492,715...20,643,465 		JBrowse link
G Ercc6 excision repair cross-complementing rodent repair deficiency, complementation group 6 increases abundance EXP ERCC6 gene mutant form results in increased abundance of Adenosine Monophosphate CTD PMID:25440059 NCBI chr14:32,513,291...32,580,990
Ensembl chr14:32,513,521...32,580,990 		JBrowse link
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 multiple interactions EXP Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]; Creatine metabolite inhibits the reaction [Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]] CTD PMID:11390963 NCBI chr 7:46,097,123...46,100,952
Ensembl chr 7:46,093,953...46,100,764 		JBrowse link
G Nudt10 nudix (nucleoside diphosphate linked moiety X)-type motif 10 multiple interactions ISO [NUDT11 protein results in increased metabolism of diadenosine 5',5''''-P1,P6-hexaphosphate] which results in increased chemical synthesis of Adenosine Monophosphate; [NUDT11 protein results in increased metabolism of P(1),P(5)-di(adenosine-5'-)pentaphosphate] which results in increased chemical synthesis of Adenosine Monophosphate CTD PMID:12121577 NCBI chr  X:6,168,696...6,173,009
Ensembl chr  X:6,168,696...6,173,015
Ensembl chr  X:6,168,696...6,173,015 		JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha increases expression ISO Adenosine Monophosphate results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr 5:51,454,249...52,115,853
Ensembl chr 5:51,454,250...51,567,726 		JBrowse link
G Trp73 transformation related protein 73 affects abundance EXP TP73 protein affects the abundance of Adenosine Monophosphate CTD PMID:25554796 NCBI chr 4:154,056,249...154,139,875
Ensembl chr 4:154,056,253...154,140,208
Ensembl chr 4:154,056,253...154,140,208 		JBrowse link
ADP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 multiple interactions
affects binding		 ISO estradiol-17 beta-glucuronide inhibits the reaction [Adenosine Diphosphate binds to ABCC1 protein mutant form]; estradiol-17 beta-glucuronide inhibits the reaction [Adenosine Diphosphate binds to ABCC1 protein]; Vanadates promotes the reaction [Adenosine Diphosphate binds to ABCC1 protein]
Adenosine Diphosphate binds to ABCC1 protein; Adenosine Diphosphate binds to ABCC1 protein mutant form		 CTD PMID:18336795 NCBI chr16:14,361,453...14,474,878
Ensembl chr16:14,361,558...14,475,737 		JBrowse link
G Ahr aryl-hydrocarbon receptor multiple interactions ISO Adenosine Diphosphate affects the folding of [Tetrachlorodibenzodioxin binds to AHR protein] CTD PMID:1848756 NCBI chr12:35,497,979...35,534,989
Ensembl chr12:35,497,974...35,535,038 		JBrowse link
G Ak1 adenylate kinase 1 increases abundance EXP AK1 protein results in increased abundance of Adenosine Diphosphate CTD PMID:11390963 NCBI chr 2:32,621,758...32,635,058
Ensembl chr 2:32,621,758...32,635,058 		JBrowse link
G Alb albumin decreases secretion
multiple interactions		 ISO Adenosine Diphosphate results in decreased secretion of ALB protein
Aspirin inhibits the reaction [Adenosine Diphosphate results in decreased secretion of ALB protein]		 CTD PMID:17303692 NCBI chr 5:90,460,870...90,476,602
Ensembl chr 5:90,460,897...90,476,602 		JBrowse link
G Axl AXL receptor tyrosine kinase decreases response to substance ISO AXL protein results in decreased susceptibility to Adenosine Diphosphate CTD PMID:15733062 NCBI chr 7:25,756,500...25,788,924
Ensembl chr 7:25,757,273...25,788,705 		JBrowse link
G Cat catalase multiple interactions ISO CAT protein inhibits the reaction [Adenosine Diphosphate results in increased glutathionylation of PTPN1 protein] CTD PMID:16781456 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160 		JBrowse link
G Cd40lg CD40 ligand increases expression
multiple interactions		 ISO
EXP		 Adenosine Diphosphate results in increased expression of CD40LG protein
clopidogrel inhibits the reaction [Adenosine Diphosphate results in increased expression of CD40LG protein]		 CTD PMID:11297035 PMID:17043144 NCBI chr  X:57,212,143...57,224,042
Ensembl chr  X:57,212,143...57,224,042 		JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator multiple interactions ISO Adenosine Diphosphate binds to and results in decreased activity of CFTR protein; P(1),P(5)-di(adenosine-5'-)pentaphosphate inhibits the reaction [Adenosine Diphosphate binds to and results in decreased activity of CFTR protein] CTD PMID:15684079 NCBI chr 6:18,170,687...18,322,770
Ensembl chr 6:18,170,687...18,322,768 		JBrowse link
G Chordc1 cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 multiple interactions EXP Adenosine Diphosphate binds to and affects the folding of CHORDC1 protein; Adenosine Diphosphate promotes the reaction [CHORDC1 protein binds to CHORDC1 protein]; Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to CHORDC1 protein] CTD PMID:23184943 NCBI chr 9:18,292,267...18,314,000
Ensembl chr 9:18,292,125...18,317,442 		JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 multiple interactions ISO CYP2C19 gene affects the susceptibility to [Adenosine Diphosphate co-treated with clopidogrel]; CYP2C19 gene SNP affects the reaction [Adenosine Diphosphate results in increased expression of SELP protein]; CYP2C19 gene SNP affects the susceptibility to [Adenosine Diphosphate co-treated with Arachidonic Acid] CTD PMID:16772608 PMID:18004210 PMID:18394438 NCBI chr19:39,389,556...39,463,103
Ensembl chr19:39,389,556...39,463,075 		JBrowse link
G Dtymk deoxythymidylate kinase multiple interactions ISO DTYMK protein binds to [N1-(4-bis(pivaloyloxymethyl)phosphinylbuten-2-yl)thymine co-treated with Adenosine Diphosphate] CTD PMID:21128666 NCBI chr 1:93,792,576...93,802,068
Ensembl chr 1:93,792,576...93,801,934 		JBrowse link
G Epha4 Eph receptor A4 increases phosphorylation
multiple interactions		 ISO Adenosine Diphosphate results in increased phosphorylation of EPHA4 protein
Benzoic Acid analog inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of EPHA4 protein]		 CTD PMID:22273509 NCBI chr 1:77,367,182...77,515,107
Ensembl chr 1:77,367,185...77,515,088 		JBrowse link
G Ern1 endoplasmic reticulum (ER) to nucleus signalling 1 multiple interactions
decreases activity		 EXP Adenosine Diphosphate inhibits the reaction [ERN1 protein binds to ERN1 protein]
Adenosine Diphosphate results in decreased activity of ERN1 protein		 CTD PMID:25164867 NCBI chr11:106,397,620...106,487,796
Ensembl chr11:106,394,650...106,487,852 		JBrowse link
G F2 coagulation factor II increases abundance
multiple interactions		 ISO F2 protein results in increased abundance of Adenosine Diphosphate
Quercetin inhibits the reaction [F2 protein results in increased abundance of Adenosine Diphosphate]; resveratrol inhibits the reaction [F2 protein results in increased abundance of Adenosine Diphosphate]		 CTD PMID:15342215 NCBI chr 2:91,612,397...91,636,457
Ensembl chr 2:91,625,320...91,636,414 		JBrowse link
G Fga fibrinogen alpha chain multiple interactions
increases secretion		 ISO Aspirin promotes the reaction [Adenosine Diphosphate results in increased secretion of FGA protein] CTD PMID:17303692 NCBI chr 3:83,026,153...83,033,627
Ensembl chr 3:83,026,076...83,033,627 		JBrowse link
G Fgb fibrinogen beta chain decreases secretion
multiple interactions		 ISO Adenosine Diphosphate results in decreased secretion of FGB protein
Aspirin inhibits the reaction [Adenosine Diphosphate results in decreased secretion of FGB protein]		 CTD PMID:17303692 NCBI chr 3:83,042,246...83,049,863
Ensembl chr 3:83,040,141...83,049,863 		JBrowse link
G Fgg fibrinogen gamma chain increases secretion
multiple interactions		 ISO Adenosine Diphosphate results in increased secretion of FGG protein
Aspirin promotes the reaction [Adenosine Diphosphate results in increased secretion of FGG protein]		 CTD PMID:17303692 NCBI chr 3:83,007,724...83,015,056
Ensembl chr 3:83,007,724...83,015,049 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions ISO Adenosine Diphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog] CTD PMID:15788719 NCBI chr 6:125,161,852...125,166,467
Ensembl chr 6:125,161,715...125,166,467 		JBrowse link
G Gas6 growth arrest specific 6 increases response to substance ISO GAS6 protein results in increased susceptibility to Adenosine Diphosphate CTD PMID:15733062 NCBI chr 8:13,465,374...13,494,535
Ensembl chr 8:13,465,374...13,494,490 		JBrowse link
G Hras Harvey rat sarcoma virus oncogene multiple interactions ISO Adenosine Diphosphate binds to and affects the folding of HRAS protein CTD PMID:16388579 NCBI chr 7:141,189,934...141,194,019
Ensembl chr 7:141,189,105...141,194,005 		JBrowse link
G Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 multiple interactions EXP Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]; Calcium promotes the reaction [Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]] CTD PMID:23184943 NCBI chr12:110,691,036...110,696,395
Ensembl chr12:110,690,605...110,702,728 		JBrowse link
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial multiple interactions
increases abundance		 EXP Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Adenosine Diphosphate] CTD PMID:27469509 NCBI chr 7:80,094,845...80,118,608
Ensembl chr 7:80,094,846...80,115,392 		JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions		 EXP Adenosine Diphosphate results in increased expression of IL6 protein
MRS 2211 inhibits the reaction [Adenosine Diphosphate results in increased expression of IL6 protein]		 CTD PMID:24849676 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981 		JBrowse link
G Itga2 integrin alpha 2 multiple interactions ISO ITGA2 gene SNP affects the susceptibility to [Aspirin co-treated with clopidogrel co-treated with Adenosine Diphosphate] CTD PMID:16214444 NCBI chr13:114,833,081...114,932,100
Ensembl chr13:114,833,081...114,932,100 		JBrowse link
G Itga2b integrin alpha 2b multiple interactions ISO cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]] CTD PMID:18404433 NCBI chr11:102,453,297...102,469,883
Ensembl chr11:102,453,297...102,470,122 		JBrowse link
G Itgb1bp2 integrin beta 1 binding protein 2 multiple interactions EXP Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to CHORDC1 protein]; Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]; Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to ITGB1BP2 protein]; Calcium promotes the reaction [Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]] CTD PMID:23184943 NCBI chr  X:101,449,088...101,466,122
Ensembl chr  X:101,449,088...101,453,541 		JBrowse link
G Itgb3 integrin beta 3 multiple interactions ISO cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]] CTD PMID:18404433 NCBI chr11:104,608,000...104,670,476
Ensembl chr11:104,608,000...104,670,476 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 increases phosphorylation ISO Adenosine Diphosphate results in increased phosphorylation of MAPK1 protein CTD PMID:15034929 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 increases phosphorylation ISO Adenosine Diphosphate results in increased phosphorylation of MAPK3 protein CTD PMID:15034929 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Dicumarol inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of MAPK8 protein] CTD PMID:24466103 NCBI chr14:33,377,898...33,447,353
Ensembl chr14:33,377,898...33,447,158 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO Dicumarol inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of MAPK9 protein] CTD PMID:24466103 NCBI chr11:49,846,728...49,886,421
Ensembl chr11:49,846,751...49,886,421 		JBrowse link
G Mertk MER proto-oncogene tyrosine kinase increases response to substance ISO MERTK protein results in increased susceptibility to Adenosine Diphosphate CTD PMID:15733062 NCBI chr 2:128,698,915...128,803,162
Ensembl chr 2:128,698,956...128,802,894 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP NOS2 protein affects the susceptibility to [Phenylephrine co-treated with Adenosine Diphosphate] CTD PMID:11498454 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254 		JBrowse link
G Nt5e 5' nucleotidase, ecto decreases activity ISO Adenosine Diphosphate analog results in decreased activity of NT5E protein CTD PMID:18404487 NCBI chr 9:88,327,609...88,372,089
Ensembl chr 9:88,327,197...88,372,092 		JBrowse link
G P2ry12 purinergic receptor P2Y, G-protein coupled 12 affects response to substance
increases response to substance
multiple interactions		 ISO
EXP		 P2RY12 gene polymorphism affects the susceptibility to Adenosine Diphosphate; P2RY12 protein affects the susceptibility to Adenosine Diphosphate
P2RY12 protein results in increased susceptibility to Adenosine Diphosphate
Epinephrine inhibits the reaction [P2RY12 gene mutant form results in decreased susceptibility to Adenosine Diphosphate]
P2RY12 protein affects the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]		 CTD PMID:11196645 PMID:11413167 PMID:18404433 PMID:23849096 NCBI chr 3:59,216,271...59,262,985
Ensembl chr 3:59,216,272...59,262,871 		JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide increases secretion
multiple interactions		 ISO Adenosine Diphosphate results in increased secretion of PDGFB protein
Aspirin promotes the reaction [Adenosine Diphosphate results in increased secretion of PDGFB protein]		 CTD PMID:17303692 NCBI chr15:79,995,865...80,024,614
Ensembl chr15:79,995,874...80,014,977 		JBrowse link
G Pf4 platelet factor 4 increases secretion ISO Adenosine Diphosphate results in increased secretion of PF4 protein CTD PMID:19428933 NCBI chr 5:90,772,435...90,773,383
Ensembl chr 5:90,772,435...90,773,383 		JBrowse link
G Pfkm phosphofructokinase, muscle multiple interactions ISO Adenosine Diphosphate inhibits the reaction [resveratrol results in decreased activity of PFKM protein] CTD PMID:23454376 NCBI chr15:98,092,589...98,132,447
Ensembl chr15:98,092,589...98,132,451 		JBrowse link
G Pgp phosphoglycolate phosphatase decreases phosphorylation EXP PGP protein results in decreased phosphorylation of Adenosine Diphosphate CTD PMID:24338473 NCBI chr17:24,470,426...24,473,110
Ensembl chr17:24,470,392...24,473,110 		JBrowse link
G Ppbp pro-platelet basic protein increases secretion ISO Adenosine Diphosphate results in increased secretion of PPBP protein CTD PMID:19428933 NCBI chr 5:90,768,518...90,770,063
Ensembl chr 5:90,768,518...90,770,063 		JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit multiple interactions ISO Adenosine Diphosphate binds to and affects the folding of PPP5C protein CTD PMID:23184943 NCBI chr 7:17,004,640...17,027,914
Ensembl chr 7:17,004,640...17,027,924 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 increases glutathionylation
multiple interactions		 ISO Adenosine Diphosphate results in increased glutathionylation of PTPN1 protein
CAT protein inhibits the reaction [Adenosine Diphosphate results in increased glutathionylation of PTPN1 protein]		 CTD PMID:16781456 NCBI chr 2:167,930,750...167,979,385
Ensembl chr 2:167,932,057...167,979,385 		JBrowse link
G Selp selectin, platelet multiple interactions
increases expression		 ISO cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]; CYP2C19 gene SNP affects the reaction [Adenosine Diphosphate results in increased expression of SELP protein]; Heparin promotes the reaction [Adenosine Diphosphate affects the localization of SELP protein]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]]; P2RY12 protein affects the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]; Quercetin inhibits the reaction [Adenosine Diphosphate results in increased expression of SELP protein] CTD PMID:9740346 PMID:18394438 PMID:18404433 PMID:23249183 NCBI chr 1:164,115,264...164,150,026
Ensembl chr 1:164,115,264...164,150,026 		JBrowse link
G Sirt3 sirtuin 3 decreases abundance EXP SIRT3 protein results in decreased abundance of Adenosine Diphosphate CTD PMID:23166782 NCBI chr 7:140,863,663...140,882,309
Ensembl chr 7:140,863,666...140,882,309 		JBrowse link
G Taldo1 transaldolase 1 increases abundance EXP TALDO1 gene mutant form results in increased abundance of Adenosine Diphosphate CTD PMID:19436114 NCBI chr 7:141,392,160...141,402,976
Ensembl chr 7:141,392,199...141,402,968 		JBrowse link
G Thbs1 thrombospondin 1 increases secretion ISO Adenosine Diphosphate results in increased secretion of THBS1 protein CTD PMID:17303692 NCBI chr 2:118,111,876...118,127,133
Ensembl chr 2:118,111,876...118,127,133 		JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase 3 increases response to substance ISO TYRO3 protein results in increased susceptibility to Adenosine Diphosphate CTD PMID:15733062 NCBI chr 2:119,797,740...119,818,104
Ensembl chr 2:119,797,733...119,818,104 		JBrowse link
G Vasp vasodilator-stimulated phosphoprotein multiple interactions
increases phosphorylation		 ISO N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of VASP protein] CTD PMID:25329809 NCBI chr 7:19,256,929...19,271,854
Ensembl chr 7:19,256,929...19,271,817 		JBrowse link
ADP-D-ribose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adprh ADP-ribosylarginine hydrolase increases hydrolysis ISO ADPRH protein results in increased hydrolysis of Adenosine Diphosphate Ribose metabolite CTD PMID:21498885 NCBI chr16:38,445,399...38,452,689
Ensembl chr16:38,444,030...38,452,703 		JBrowse link
G Adprs ADP-ribosylserine hydrolase increases hydrolysis
multiple interactions		 ISO ADPRS protein results in increased hydrolysis of Adenosine Diphosphate Ribose metabolite
Adenosine Diphosphate Ribose inhibits the reaction [ADPRS protein results in increased hydrolysis of O-Acetyl-ADP-Ribose]		 CTD PMID:21498885 NCBI chr 4:126,316,351...126,321,703
Ensembl chr 4:126,316,047...126,321,703 		JBrowse link
G Nos1 nitric oxide synthase 1, neuronal multiple interactions EXP NOS1 protein affects the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased ribosylation of Adenosine Diphosphate Ribose] CTD PMID:10318960 NCBI chr 5:117,866,839...117,958,840
Ensembl chr 5:117,781,032...117,958,840 		JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 multiple interactions
increases activity		 ISO
EXP		 Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]; Clotrimazole inhibits the reaction [Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]]; Flufenamic Acid inhibits the reaction [Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]]
Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein
2-aminoethoxydiphenyl borate inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; 4-amylcinnamoylanthranilic acid inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Copper Sulfate inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; ferrous chloride inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; lead nitrate inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Mercuric Chloride inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Miconazole inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Selenium Oxides inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]
TRPM2 protein promotes the reaction [Adenosine Diphosphate Ribose results in increased uptake of Calcium]		 CTD PMID:18204483 PMID:20878536 PMID:21900507 PMID:22750002 NCBI chr10:77,907,722...77,969,909
Ensembl chr10:77,907,722...77,970,563 		JBrowse link
AMP-PNP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl-hydrocarbon receptor multiple interactions ISO Adenylyl Imidodiphosphate affects the folding of [Tetrachlorodibenzodioxin binds to AHR protein] CTD PMID:1848756 NCBI chr12:35,497,979...35,534,989
Ensembl chr12:35,497,974...35,535,038 		JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator affects activity ISO Adenylyl Imidodiphosphate affects the activity of CFTR protein CTD PMID:15657297 NCBI chr 6:18,170,687...18,322,770
Ensembl chr 6:18,170,687...18,322,768 		JBrowse link
G Ptgdr prostaglandin D receptor multiple interactions ISO Adenylyl Imidodiphosphate inhibits the reaction [Prostaglandin D2 binds to PTGDR protein] CTD PMID:9579725 NCBI chr14:44,851,235...44,859,375
Ensembl chr14:44,851,235...44,859,375 		JBrowse link
arachidonoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO arachidonyl-coenzyme A binds to and results in increased activity of PPARA protein CTD PMID:11139385 NCBI chr15:85,734,910...85,806,851
Ensembl chr15:85,734,983...85,802,819 		JBrowse link
ATP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca8b ATP-binding cassette, sub-family A (ABC1), member 8b multiple interactions ISO Adenosine Triphosphate affects the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide] CTD PMID:12379217 NCBI chr11:109,932,206...109,996,274
Ensembl chr11:109,932,190...109,995,845 		JBrowse link
G Abcb11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 multiple interactions ISO Adenosine Triphosphate promotes the reaction [ABCB11 protein results in increased uptake of fexofenadine] CTD PMID:18245269 NCBI chr 2:69,238,282...69,342,616
Ensembl chr 2:69,238,282...69,342,616 		JBrowse link
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A multiple interactions
increases hydrolysis		 ISO [Cobalt results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate; [Magnesium results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate; [Manganese results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate; ABCB1 protein binds to and results in increased hydrolysis of Adenosine Triphosphate; aurapten promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]; crizotinib promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]; Disulfiram affects the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]; lapatinib promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]; nobiletin promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]
[Rifampin metabolite results in decreased activity of ABCB1A protein] which results in decreased abundance of Adenosine Triphosphate		 CTD PMID:2900677 PMID:14978246 PMID:18829547 PMID:18955043 PMID:22233293 PMID:23685082 NCBI chr 5:8,567,091...8,748,575
Ensembl chr 5:8,660,077...8,748,575 		JBrowse link
G Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 multiple interactions
affects activity
increases hydrolysis
affects binding		 ISO
EXP		 [Adenosine Triphosphate affects the activity of ABCC1 protein] which results in increased transport of Acetaminophen metabolite; ABCC1 protein binds to and results in increased degradation of Adenosine Triphosphate; ABCC1 protein binds to and results in increased hydrolysis of Adenosine Triphosphate; ABCC1 protein mutant form binds to and results in increased hydrolysis of Adenosine Triphosphate; Adenosine Triphosphate binds to and affects the folding of ABCC1 protein; Adenosine Triphosphate promotes the reaction [ABCC1 protein affects the transport of Bilirubin]; Adenosine Triphosphate promotes the reaction [ABCC1 protein affects the transport of estradiol-17 beta-glucuronide]; Adenosine Triphosphate promotes the reaction [ABCC1 protein affects the transport of Leukotriene C4]; daidzein promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Disulfiram affects the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; hesperetin promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; naringenin promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; nobiletin promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Quercetin affects the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Resveratrol promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Silymarin inhibits the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]
Daunorubicin promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Vanadates inhibits the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]
Adenosine Triphosphate binds to ABCC1 protein		 CTD PMID:10856430 PMID:11278000 PMID:14978246 PMID:15245331 PMID:15355964 PMID:15459206 PMID:15737336 PMID:15838832 PMID:16156793 PMID:18336795 PMID:18955043 PMID:32472168 NCBI chr16:14,361,453...14,474,878
Ensembl chr16:14,361,558...14,475,737 		JBrowse link
G Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 multiple interactions
affects activity
affects metabolic processing		 ISO
EXP		 Adenosine Triphosphate promotes the reaction [ABCC2 protein results in increased secretion of Fluo-3]; Adenosine Triphosphate promotes the reaction [ABCC2 protein results in increased transport of temocaprilat]
Adenosine Triphosphate affects the activity of ABCC2 protein
[Adenosine Triphosphate affects the activity of ABCC2 protein] which results in increased transport of Acetaminophen metabolite; [Adenosine Triphosphate co-treated with ABCC2 protein] results in increased uptake of estradiol-17 beta-glucuronide; Adenosine Triphosphate affects the reaction [ABCC2 protein results in increased transport of Mercury]; verlukast inhibits the reaction [[Adenosine Triphosphate co-treated with ABCC2 protein] results in increased uptake of estradiol-17 beta-glucuronide]
ABCC2 protein affects the metabolism of Adenosine Triphosphate
Adenosine Triphosphate promotes the reaction [ABCC2 protein results in increased transport of S-1,2-dichlorovinyl-N-acetylcysteine]		 CTD PMID:9067317 PMID:9794919 PMID:20060011 PMID:22027652 PMID:24039982 PMID:32003934 PMID:32472168 NCBI chr19:43,782,308...43,838,332
Ensembl chr19:43,782,192...43,840,740 		JBrowse link
G Abcc3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 multiple interactions EXP Adenosine Triphosphate promotes the reaction [ABCC3 protein affects the transport of fexofenadine] CTD PMID:18245269 NCBI chr11:94,343,295...94,393,017
Ensembl chr11:94,343,295...94,392,997 		JBrowse link
G Abcc4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 multiple interactions
affects activity
increases hydrolysis		 ISO [Adenosine Triphosphate affects the activity of ABCC4 protein] which results in increased transport of Acetaminophen metabolite; ABCC4 protein binds to and results in increased hydrolysis of Adenosine Triphosphate; daidzein promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; Disulfiram inhibits the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; hesperetin promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; naringenin promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; Quercetin affects the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; Quercetin inhibits the reaction [Alprostadil promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]]; Resveratrol promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; Silymarin inhibits the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; Silymarin inhibits the reaction [Alprostadil promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]] CTD PMID:14978246 PMID:16156793 PMID:32472168 NCBI chr14:118,482,692...118,707,856
Ensembl chr14:118,482,692...118,706,219 		JBrowse link
G Abcc6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 affects binding ISO Adenosine Triphosphate binds to ABCC6 protein CTD PMID:11880368 NCBI chr 7:45,974,110...46,030,491
Ensembl chr 7:45,967,555...46,030,302 		JBrowse link
G Abcc8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 multiple interactions ISO Adenosine Triphosphate deficiency inhibits the reaction [Estradiol inhibits the reaction [Glyburide binds to ABCC8 protein]] CTD PMID:19095654 NCBI chr 7:46,104,523...46,180,039
Ensembl chr 7:46,104,523...46,180,033 		JBrowse link
G Abcc9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 multiple interactions ISO
EXP		 Adenosine Triphosphate results in decreased activity of [KCNJ8 protein binds to ABCC9 protein]
Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]; Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]; Creatine metabolite inhibits the reaction [Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]]		 CTD PMID:11390963 PMID:28842488 NCBI chr 6:142,587,862...142,702,766
Ensembl chr 6:142,587,862...142,702,315 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) increases hydrolysis
multiple interactions		 ISO ABCG2 protein results in increased hydrolysis of Adenosine Triphosphate
[Adenosine Triphosphate co-treated with ABCG2 protein] results in increased uptake of estrone sulfate; Lapatinib promotes the reaction [ABCG2 protein results in increased hydrolysis of Adenosine Triphosphate]; Sulfasalazine inhibits the reaction [[Adenosine Triphosphate co-treated with ABCG2 protein] results in increased uptake of estrone sulfate]		 CTD PMID:18829547 PMID:32003934 NCBI chr 6:58,584,491...58,692,451
Ensembl chr 6:58,584,523...58,695,676 		JBrowse link
G Abl1 c-abl oncogene 1, non-receptor tyrosine kinase multiple interactions ISO [ABL1 protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein; sorafenib inhibits the reaction [[ABL1 protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein] CTD PMID:19366808 NCBI chr 2:31,688,244...31,807,093
Ensembl chr 2:31,688,376...31,804,227 		JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 increases secretion ISO ADCYAP1 protein results in increased secretion of Adenosine Triphosphate CTD PMID:18563302 NCBI chr17:93,198,245...93,206,541
Ensembl chr17:93,199,017...93,206,537 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a decreases expression
multiple interactions		 ISO Adenosine Triphosphate results in decreased expression of AGTR1A mRNA
Adenosine Triphosphate results in decreased expression of and results in decreased activity of AGTR1A protein; ARRB2 protein affects the reaction [Adenosine Triphosphate results in decreased activity of AGTR1A protein]; CABIN1 protein inhibits the reaction [Adenosine Triphosphate results in decreased expression of and results in decreased activity of AGTR1A protein]; Cyclosporine inhibits the reaction [Adenosine Triphosphate results in decreased expression of AGTR1A mRNA]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Adenosine Triphosphate results in decreased expression of AGTR1A mRNA]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Adenosine Triphosphate results in decreased expression of AGTR1A protein]		 CTD PMID:21464294 NCBI chr13:30,336,356...30,382,867
Ensembl chr13:30,336,441...30,382,867 		JBrowse link
G Ahr aryl-hydrocarbon receptor multiple interactions ISO Adenosine Triphosphate affects the folding of [Tetrachlorodibenzodioxin binds to AHR protein] CTD PMID:1848756 NCBI chr12:35,497,979...35,534,989
Ensembl chr12:35,497,974...35,535,038 		JBrowse link
G Akt1 thymoma viral proto-oncogene 1 decreases activity
multiple interactions		 ISO Adenosine Triphosphate results in decreased activity of AKT1 protein
Alcohols inhibits the reaction [Adenosine Triphosphate results in decreased activity of AKT1 protein]		 CTD PMID:24300283 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884 		JBrowse link
G Aldh5a1 aldhehyde dehydrogenase family 5, subfamily A1 increases abundance EXP ALDH5A1 gene mutant form results in increased abundance of Adenosine Triphosphate CTD PMID:29031482 NCBI chr13:24,907,579...24,937,661
Ensembl chr13:24,907,579...24,937,661 		JBrowse link
G Alk anaplastic lymphoma kinase affects binding
multiple interactions		 ISO ALK protein binds to Adenosine Triphosphate
[ALK protein mutant form promotes the reaction [ALK protein binds to Adenosine Triphosphate]] which results in decreased susceptibility to crizotinib; ALK protein mutant form promotes the reaction [ALK protein binds to Adenosine Triphosphate]		 CTD PMID:22072639 NCBI chr17:71,868,988...72,604,702
Ensembl chr17:71,868,972...72,604,627 		JBrowse link
G Alpl alkaline phosphatase, liver/bone/kidney multiple interactions
increases response to substance		 EXP ALPL gene mutant form promotes the reaction [Adenosine Triphosphate results in increased expression of FOS mRNA]
ALPL gene mutant form results in increased susceptibility to Adenosine Triphosphate		 CTD PMID:27466191 NCBI chr 4:137,741,731...137,796,384
Ensembl chr 4:137,741,733...137,796,384 		JBrowse link
G Anxa1 annexin A1 multiple interactions ISO [Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein; arsenite affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]; Cadmium affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]; chromium hexavalent ion affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]; Lead affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein] CTD PMID:20655937 NCBI chr19:20,373,434...20,390,671
Ensembl chr19:20,373,428...20,390,944 		JBrowse link
G App amyloid beta (A4) precursor protein multiple interactions
increases secretion		 ISO Adenosine Triphosphate inhibits the reaction [Hydrogen Peroxide results in decreased secretion of APP protein modified form]; Adenosine Triphosphate inhibits the reaction [Rotenone results in decreased secretion of APP protein modified form]; Rotenone inhibits the reaction [Adenosine Triphosphate results in increased secretion of APP protein modified form]; Sodium Azide inhibits the reaction [Adenosine Triphosphate results in increased secretion of APP protein modified form] CTD PMID:22906069 NCBI chr16:84,952,666...85,175,255
Ensembl chr16:84,949,685...85,173,766 		JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions ISO Adenosine Triphosphate promotes the reaction [RELA protein binds to ARRB2 protein]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to ARRB2 protein]]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to NFKBIA protein]]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to NOS2 protein]]; ARRB2 protein affects the reaction [Adenosine Triphosphate results in decreased activity of AGTR1A protein] CTD PMID:21464294 NCBI chr11:70,432,485...70,440,828
Ensembl chr11:70,432,635...70,440,828 		JBrowse link
G Asic1 acid-sensing (proton-gated) ion channel 1 multiple interactions ISO [Acids binds to and affects the activity of ASIC1 protein] which results in increased secretion of Adenosine Triphosphate CTD PMID:19860742 NCBI chr15:99,670,197...99,701,130
Ensembl chr15:99,670,368...99,701,130 		JBrowse link
G Asic2 acid-sensing (proton-gated) ion channel 2 multiple interactions ISO [Acids binds to and affects the activity of ASIC2 protein] which results in increased secretion of Adenosine Triphosphate CTD PMID:19860742 NCBI chr11:80,880,163...81,968,396
Ensembl chr11:80,880,169...81,968,457 		JBrowse link
G Asic3 acid-sensing (proton-gated) ion channel 3 multiple interactions ISO [Acids binds to and affects the activity of ASIC3 protein] which results in increased secretion of Adenosine Triphosphate CTD PMID:19860742 NCBI chr 5:24,413,451...24,417,840
Ensembl chr 5:24,413,392...24,417,835 		JBrowse link
G Atp7a ATPase, Cu++ transporting, alpha polypeptide multiple interactions ISO [Copper co-treated with Adenosine Triphosphate] results in increased phosphorylation of ATP7A protein CTD PMID:20964302 NCBI chr  X:106,027,224...106,128,161
Ensembl chr  X:106,027,276...106,124,926 		JBrowse link
G Atp7b ATPase, Cu++ transporting, beta polypeptide multiple interactions
increases phosphorylation		 ISO [Copper co-treated with Adenosine Triphosphate] results in increased phosphorylation of ATP7B protein
Adenosine Triphosphate results in increased phosphorylation of ATP7B protein		 CTD PMID:19405516 PMID:20964302 NCBI chr 8:21,992,783...22,060,074
Ensembl chr 8:21,992,785...22,060,305 		JBrowse link
G Atp8b1 ATPase, class I, type 8B, member 1 increases hydrolysis ISO ATP8B1 protein results in increased hydrolysis of Adenosine Triphosphate CTD PMID:11584374 NCBI chr18:64,528,979...64,661,272
Ensembl chr18:64,528,967...64,661,267 		JBrowse link
G Avp arginine vasopressin multiple interactions
increases secretion		 ISO Adenosine Triphosphate promotes the reaction [Phenylephrine results in increased secretion of AVP protein]; bisindolylmaleimide I inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein]; Dactinomycin inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased secretion of AVP protein] CTD PMID:11102496 NCBI chr 2:130,580,620...130,582,588
Ensembl chr 2:130,580,620...130,582,554 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO [Adenosine Triphosphate binds to P2RY11 protein] which results in decreased expression of BCL2 protein CTD PMID:21503959 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274 		JBrowse link
G Bcr BCR activator of RhoGEF and GTPase multiple interactions ISO [BCR protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein; sorafenib inhibits the reaction [[BCR protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein] CTD PMID:19366808 NCBI chr10:75,060,560...75,184,923
Ensembl chr10:75,060,592...75,184,921 		JBrowse link
G Cabin1 calcineurin binding protein 1 multiple interactions ISO CABIN1 protein inhibits the reaction [Adenosine Triphosphate results in decreased expression of and results in decreased activity of AGTR1A protein] CTD PMID:21464294 NCBI chr10:75,646,110...75,764,357
Ensembl chr10:75,646,112...75,764,341 		JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha increases secretion
multiple interactions		 ISO Adenosine Triphosphate results in increased secretion of CALCA protein
Adenosine Triphosphate promotes the reaction [Protons results in increased secretion of CALCA protein]; Flurbiprofen inhibits the reaction [Adenosine Triphosphate promotes the reaction [Protons results in increased secretion of CALCA protein]]; Suramin inhibits the reaction [Adenosine Triphosphate promotes the reaction [Protons results in increased secretion of CALCA protein]]		 CTD PMID:12044622 NCBI chr 7:114,625,981...114,636,910
Ensembl chr 7:114,631,478...114,636,357 		JBrowse link
G Casp1 caspase 1 increases activity
multiple interactions		 ISO
EXP		 Adenosine Triphosphate results in increased activity of CASP1 mRNA; Adenosine Triphosphate results in increased activity of CASP1 protein
[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of CASP1 mRNA; [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased secretion of and results in increased activity of CASP1 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein; fraxinellone inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein]; KN 62 inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of CASP1 mRNA]; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased secretion of and results in increased activity of CASP1 protein]
[Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to CASP1 protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [PML protein binds to CASP1 protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein; Adenosine Triphosphate promotes the reaction [[CSTB gene mutant form results in increased susceptibility to lipopolysaccharide, E coli O55-B5] which results in increased cleavage of CASP1 protein]; Arsenic Trioxide inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to CASP1 protein]]; PYCARD protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]		 CTD PMID:18604214 PMID:19130485 PMID:21832250 PMID:23430110 PMID:24149798 PMID:25288807 PMID:25448682 PMID:26431797 PMID:26586371 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290 		JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions		 ISO Adenosine Triphosphate results in increased expression of CASP3
Suramin inhibits the reaction [Adenosine Triphosphate results in increased expression of CASP3]		 CTD PMID:19448140 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689 		JBrowse link
G Casp4 caspase 4, apoptosis-related cysteine peptidase multiple interactions ISO
EXP		 [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of CASP4 mRNA; [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased secretion of and results in increased activity of CASP4 protein; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of CASP4 mRNA]; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased secretion of and results in increased activity of CASP4 protein]
Adenosine Triphosphate promotes the reaction [[CSTB gene mutant form results in increased susceptibility to lipopolysaccharide, E coli O55-B5] which results in increased cleavage of CASP4 protein]		 CTD PMID:24149798 PMID:25288807 NCBI chr 9:5,308,849...5,336,791
Ensembl chr 9:5,308,828...5,336,783 		JBrowse link
G Cat catalase increases expression ISO Adenosine Triphosphate results in increased expression of CAT mRNA CTD PMID:22129738 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160 		JBrowse link
G Ccl3 chemokine (C-C motif) ligand 3 increases secretion
multiple interactions		 EXP Adenosine Triphosphate results in increased secretion of CCL3 protein
azetidine inhibits the reaction [Adenosine Triphosphate results in increased secretion of CCL3 protein]		 CTD PMID:26522449 NCBI chr11:83,647,843...83,649,378
Ensembl chr11:83,647,844...83,649,355 		JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator multiple interactions ISO 3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [Adenosine Triphosphate promotes the reaction [CFTR protein results in increased export of Chlorides]]; [Phosphatidylinositol 4,5-Diphosphate co-treated with Adenosine Triphosphate] results in increased activity of CFTR protein; Adenosine Triphosphate affects the reaction [Curcumin results in increased activity of CFTR protein mutant form]; Adenosine Triphosphate binds to and results in increased activity of CFTR protein; Adenosine Triphosphate promotes the reaction [CFTR protein results in increased export of Chlorides] CTD PMID:14710196 PMID:15623556 PMID:17178710 PMID:20675434 NCBI chr 6:18,170,687...18,322,770
Ensembl chr 6:18,170,687...18,322,768 		JBrowse link
G Chordc1 cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 multiple interactions ISO
EXP		 Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to PPP5C protein]; Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to SUGT1 protein]
Adenosine Triphosphate binds to and affects the folding of CHORDC1 protein; Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to CHORDC1 protein]; Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to HSP90AA1 protein]; Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to CHORDC1 protein]		 CTD PMID:23184943 NCBI chr 9:18,292,267...18,314,000
Ensembl chr 9:18,292,125...18,317,442 		JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO [Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased activity of COMT protein] which results in decreased abundance of Adenosine Triphosphate; [tolcapone results in decreased activity of COMT protein] which results in decreased abundance of Adenosine Triphosphate CTD PMID:14975680 NCBI chr16:18,406,882...18,426,716
Ensembl chr16:18,406,886...18,426,852 		JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 multiple interactions ISO [Bezafibrate results in increased activity of CPT2 protein] which results in increased abundance of Adenosine Triphosphate; Carnitine promotes the reaction [[Bezafibrate results in increased activity of CPT2 protein] which results in increased abundance of Adenosine Triphosphate] CTD PMID:21816645 NCBI chr 4:107,903,982...107,923,589
Ensembl chr 4:107,903,981...107,923,610 		JBrowse link
G Crkl v-crk avian sarcoma virus CT10 oncogene homolog-like multiple interactions ISO [ABL1 protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein; [BCR protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein; sorafenib inhibits the reaction [[ABL1 protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein]; sorafenib inhibits the reaction [[BCR protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein] CTD PMID:19366808 NCBI chr16:17,451,985...17,487,440
Ensembl chr16:17,451,987...17,487,434 		JBrowse link
G Csnk2a1 casein kinase 2, alpha 1 polypeptide multiple interactions
affects binding		 ISO 5-(3-chlorophenylamino)benzo(c)(2,6)naphthyridine-8-carboxylic acid inhibits the reaction [Adenosine Triphosphate binds to [CSNK2A1 protein binds to CSNK2A1 protein binds to CSNK2B protein binds to CSNK2B protein]] CTD PMID:21174434 NCBI chr 2:152,226,535...152,281,856
Ensembl chr 2:152,226,839...152,281,852 		JBrowse link
G Csnk2b casein kinase 2, beta polypeptide multiple interactions
affects binding		 ISO 5-(3-chlorophenylamino)benzo(c)(2,6)naphthyridine-8-carboxylic acid inhibits the reaction [Adenosine Triphosphate binds to [CSNK2A1 protein binds to CSNK2A1 protein binds to CSNK2B protein binds to CSNK2B protein]] CTD PMID:21174434 NCBI chr17:35,116,195...35,122,053
Ensembl chr17:35,116,196...35,122,053 		JBrowse link
G Cstb cystatin B multiple interactions EXP Adenosine Triphosphate promotes the reaction [[CSTB gene mutant form results in increased susceptibility to lipopolysaccharide, E coli O55-B5] which results in increased cleavage of CASP1 protein]; Adenosine Triphosphate promotes the reaction [[CSTB gene mutant form results in increased susceptibility to lipopolysaccharide, E coli O55-B5] which results in increased cleavage of CASP4 protein] CTD PMID:25288807 NCBI chr10:78,425,670...78,427,622
Ensembl chr10:78,425,669...78,427,622 		JBrowse link
G Ctsb cathepsin B increases activity
multiple interactions		 EXP Adenosine Triphosphate results in increased activity of CTSB protein
azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased expression of CTSB protein]		 CTD PMID:26522449 NCBI chr14:63,122,462...63,145,923
Ensembl chr14:63,122,462...63,145,923 		JBrowse link
G Cxcl2 chemokine (C-X-C motif) ligand 2 increases secretion
multiple interactions		 EXP Adenosine Triphosphate results in increased secretion of CXCL2 protein
azetidine inhibits the reaction [Adenosine Triphosphate results in increased secretion of CXCL2 protein]		 CTD PMID:26522449 NCBI chr 5:90,903,899...90,905,938
Ensembl chr 5:90,903,871...90,905,938 		JBrowse link
G Dmd dystrophin, muscular dystrophy increases secretion
multiple interactions		 EXP DMD gene mutant form results in increased secretion of Adenosine Triphosphate
Nifedipine inhibits the reaction [DMD gene mutant form results in increased secretion of Adenosine Triphosphate]		 CTD PMID:24349043 NCBI chr  X:82,814,664...85,205,050
Ensembl chr  X:82,948,870...85,206,141 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases phosphorylation		 ISO sodium arsenite promotes the reaction [Adenosine Triphosphate results in increased phosphorylation of EGFR protein] CTD PMID:26104857 NCBI chr11:16,752,203...16,913,907
Ensembl chr11:16,752,203...16,918,158 		JBrowse link
G Egr1 early growth response 1 multiple interactions
increases expression		 ISO Iodoacetates inhibits the reaction [Adenosine Triphosphate results in increased expression of EGR1 mRNA]; Potassium Cyanide inhibits the reaction [Adenosine Triphosphate results in increased expression of EGR1 mRNA]; Sodium Azide inhibits the reaction [Adenosine Triphosphate results in increased expression of EGR1 mRNA] CTD PMID:10723097 NCBI chr18:34,861,207...34,864,956
Ensembl chr18:34,859,823...34,864,984 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 multiple interactions ISO Adenosine Triphosphate promotes the reaction [Toluene 2,4-Diisocyanate results in increased expression of ENPP2 protein] CTD PMID:26072274 NCBI chr15:54,838,901...54,952,789
Ensembl chr15:54,838,901...54,952,892 		JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 decreases activity ISO Adenosine Triphosphate results in decreased activity of ENPP7 protein CTD PMID:12885774 NCBI chr11:118,988,181...118,993,221
Ensembl chr11:118,988,188...118,993,221 		JBrowse link
G Ercc6 excision repair cross-complementing rodent repair deficiency, complementation group 6 decreases abundance
multiple interactions		 EXP ERCC6 gene mutant form results in decreased abundance of Adenosine Triphosphate
nicotinamide-beta-riboside inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Adenosine Triphosphate]		 CTD PMID:25440059 NCBI chr14:32,513,291...32,580,990
Ensembl chr14:32,513,521...32,580,990 		JBrowse link
G F2 coagulation factor II multiple interactions
increases transport
increases abundance
increases secretion		 ISO
EXP		 calmidazolium affects the reaction [F2 protein results in increased secretion of Adenosine Triphosphate]; Fendiline affects the reaction [F2 protein results in increased secretion of Adenosine Triphosphate]; Quercetin inhibits the reaction [F2 protein results in increased abundance of Adenosine Triphosphate]; resveratrol inhibits the reaction [F2 protein results in increased abundance of Adenosine Triphosphate]
STXBP2 protein affects the reaction [F2 protein results in increased transport of Adenosine Triphosphate]		 CTD PMID:2030746 PMID:15342215 PMID:30696774 NCBI chr 2:91,612,397...91,636,457
Ensembl chr 2:91,625,320...91,636,414 		JBrowse link
G Fasn fatty acid synthase multiple interactions
decreases abundance		 ISO FASN protein promotes the reaction [rosiglitazone promotes the reaction [PPARG protein results in decreased abundance of Adenosine Triphosphate]]; Protein Kinase Inhibitors inhibits the reaction [FASN protein results in decreased abundance of Adenosine Triphosphate] CTD PMID:26670611 NCBI chr11:120,805,958...120,825,166
Ensembl chr11:120,805,846...120,824,547 		JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression
multiple interactions		 ISO
EXP		 Adenosine Triphosphate results in increased expression of FOS mRNA
ALPL gene mutant form promotes the reaction [Adenosine Triphosphate results in increased expression of FOS mRNA]
[Phenylephrine co-treated with Adenosine Triphosphate] results in increased expression of FOS mRNA; Glucose affects the reaction [Adenosine Triphosphate results in increased expression of FOS mRNA]; Iodoacetates inhibits the reaction [Adenosine Triphosphate results in increased expression of FOS mRNA]; Potassium Cyanide inhibits the reaction [Adenosine Triphosphate results in increased expression of FOS mRNA]; Sodium Azide inhibits the reaction [Adenosine Triphosphate results in increased expression of FOS mRNA]		 CTD PMID:10723097 PMID:19463813 PMID:27466191 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273 		JBrowse link
G Fscn1 fascin actin-bundling protein 1 increases expression
multiple interactions		 ISO
EXP		 Adenosine Triphosphate results in increased expression of FSCN1 mRNA
Niclosamide inhibits the reaction [Adenosine Triphosphate results in increased expression of FSCN1 mRNA]		 CTD PMID:29733962 NCBI chr 5:142,960,355...142,973,189
Ensembl chr 5:142,960,343...142,973,185 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions ISO Adenosine Triphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog] CTD PMID:15788719 NCBI chr 6:125,161,852...125,166,467
Ensembl chr 6:125,161,715...125,166,467 		JBrowse link
G Gh growth hormone multiple interactions
increases secretion		 ISO NCS1 protein promotes the reaction [Adenosine Triphosphate results in increased secretion of GH1 protein]; oxophenylarsine inhibits the reaction [NCS1 protein promotes the reaction [Adenosine Triphosphate results in increased secretion of GH1 protein]]
oxophenylarsine inhibits the reaction [Adenosine Triphosphate results in increased secretion of GH1 protein]; Phosphatidylinositol 4,5-Diphosphate affects the reaction [Adenosine Triphosphate results in increased secretion of GH1 protein]		 CTD PMID:12471042 NCBI chr11:106,300,261...106,303,703
Ensembl chr11:106,300,271...106,301,865 		JBrowse link
G Gja1 gap junction protein, alpha 1 increases export ISO GJA1 protein mutant form results in increased export of Adenosine Triphosphate; GJA1 protein results in increased export of Adenosine Triphosphate CTD PMID:17687502 NCBI chr10:56,377,300...56,390,419
Ensembl chr10:56,377,330...56,402,513 		JBrowse link
G Gm40318 predicted gene, 40318 increases expression ISO Adenosine Triphosphate results in increased expression of S100P mRNA CTD PMID:29733962 NCBI chr 5:36,762,504...36,767,419
Ensembl chr 5:36,762,617...36,766,695 		JBrowse link
G Gstp1 glutathione S-transferase, pi 1 multiple interactions ISO [GSTP1 protein co-treated with Glutathione] inhibits the reaction [[Adenosine Triphosphate results in increased metabolism of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-amino-1-methyl-6-phenolimidazo(4,5-b)pyridine-DNA adduct]; [GSTP1 protein co-treated with Glutathione] inhibits the reaction [Adenosine Triphosphate results in increased activity of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine] CTD PMID:11196146 NCBI chr19:4,035,411...4,037,912
Ensembl chr19:4,035,407...4,037,985 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit multiple interactions ISO Adenosine Triphosphate inhibits the reaction [protoporphyrin IX results in decreased activity of HIF1A protein] CTD PMID:23624237 NCBI chr12:73,901,324...73,947,554
Ensembl chr12:73,901,375...73,947,530 		JBrowse link
G Hmgb1 high mobility group box 1 affects chemical synthesis
multiple interactions		 EXP HMGB1 protein affects the chemical synthesis of Adenosine Triphosphate
Adenosine Triphosphate promotes the reaction [fullerene C60 results in increased secretion of HMGB1 protein]; Adenosine Triphosphate promotes the reaction [graphene oxide results in increased secretion of HMGB1 protein]; Adenosine Triphosphate promotes the reaction [Nanotubes, Carbon results in increased secretion of HMGB1 protein]		 CTD PMID:21641551 PMID:31504961 NCBI chr 5:149,046,702...149,053,057
Ensembl chr 5:149,046,702...149,184,489 		JBrowse link
G Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 multiple interactions EXP Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to HSP90AA1 protein]; Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]; Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]] CTD PMID:23184943 NCBI chr12:110,691,036...110,696,395
Ensembl chr12:110,690,605...110,702,728 		JBrowse link
G Hspa5 heat shock protein 5 multiple interactions ISO [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of HSPA5 mRNA; [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of HSPA5 protein; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of HSPA5 mRNA]; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of HSPA5 protein] CTD PMID:24149798 NCBI chr 2:34,772,090...34,776,529
Ensembl chr 2:34,771,970...34,777,547 		JBrowse link
G Hspb1 heat shock protein 1 affects chemical synthesis EXP HSPB1 protein affects the chemical synthesis of Adenosine Triphosphate CTD PMID:21641551 NCBI chr 5:135,887,919...135,889,563
Ensembl chr 5:135,887,919...135,889,563 		JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) multiple interactions
increases expression		 ISO bisindolylmaleimide I inhibits the reaction [Adenosine Triphosphate results in increased expression of HSPD1 protein]; chelerythrine inhibits the reaction [Adenosine Triphosphate results in increased expression of HSPD1 protein]; Neomycin inhibits the reaction [Adenosine Triphosphate results in increased expression of HSPD1 protein]; Resveratrol inhibits the reaction [Adenosine Triphosphate results in increased expression of HSPD1 protein]; tricyclodecane-9-yl-xanthogenate inhibits the reaction [Adenosine Triphosphate results in increased expression of HSPD1 protein] CTD PMID:16178011 NCBI chr 1:55,077,833...55,088,243
Ensembl chr 1:55,077,835...55,088,243 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Adenosine Triphosphate inhibits the reaction [Fructose results in increased expression of ICAM1 protein] CTD PMID:18508964 NCBI chr 9:21,015,940...21,028,814
Ensembl chr 9:21,015,985...21,028,817 		JBrowse link
G Ifng interferon gamma multiple interactions EXP Adenosine Triphosphate promotes the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased abundance of Dinoprostone] CTD PMID:14623498 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892 		JBrowse link
G Il12b interleukin 12b multiple interactions ISO Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein] CTD PMID:17707769 NCBI chr11:44,400,063...44,414,677
Ensembl chr11:44,400,063...44,414,033 		JBrowse link
G Il18 interleukin 18 multiple interactions
increases secretion		 ISO
EXP		 [Adenosine Triphosphate co-treated with K-12 lipopolysaccharide] results in increased secretion of IL18 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL18 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 mRNA; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein; resveratrol promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 mRNA]; resveratrol promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein]
Adenosine Triphosphate results in increased secretion of IL18 protein
3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL18 protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL18 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 mRNA; Acetylcysteine inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL18 protein]; diphenyleneiodonium inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL18 protein]		 CTD PMID:17404311 PMID:24149798 PMID:26431797 PMID:27311643 NCBI chr 9:50,554,700...50,581,841
Ensembl chr 9:50,554,827...50,581,840 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions EXP (N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1A protein]; (N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) inhibits the reaction [Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein]]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1A protein; Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein] CTD PMID:26068648 NCBI chr 2:129,299,609...129,310,186
Ensembl chr 2:129,299,610...129,309,972 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases secretion
decreases abundance		 ISO
EXP		 Enzyme Inhibitors inhibits the reaction [IL1B protein results in decreased abundance of Adenosine Triphosphate]; IL1B protein inhibits the reaction [Adenosine Triphosphate results in increased secretion of INS1 protein]; Quercetin inhibits the reaction [IL1B protein inhibits the reaction [Adenosine Triphosphate results in increased secretion of INS1 protein]]
Adenosine Triphosphate results in increased secretion of IL1B protein
(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; (N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) inhibits the reaction [Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]; 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL1B protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased activity of and results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B mRNA; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of and results in increased cleavage of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein; Acetylcysteine inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL1B protein]; Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; Adenosine Triphosphate promotes the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased abundance of Dinoprostone]; Adenosine Triphosphate promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; Adenosine Triphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Arsenic Trioxide inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]; diphenyleneiodonium inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL1B protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of IL1B protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of and results in increased cleavage of IL1B protein]; Okadaic Acid inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; PML protein promotes the reaction [[resiquimod co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]; PYCARD protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of and results in increased cleavage of IL1B protein]; zinc chloride inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]]
[Adenosine Triphosphate co-treated with K-12 lipopolysaccharide] results in increased secretion of IL1B protein modified form; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of and results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased cleavage of and results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B mRNA; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein; Adenosine Triphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Adenosine Triphosphate results in increased cleavage of and results in increased secretion of IL1B protein; Apigenin inhibits the reaction [Adenosine Triphosphate results in increased cleavage of and results in increased secretion of IL1B protein]; flavone analog inhibits the reaction [Adenosine Triphosphate results in increased cleavage of and results in increased secretion of IL1B protein]; KN 62 inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of IL1B protein]; MitoTEMPO inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; Resveratrol inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL1B protein]; Resveratrol inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B mRNA]; Resveratrol promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; tyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone analog inhibits the reaction [Adenosine Triphosphate results in increased cleavage of and results in increased secretion of IL1B protein]		 CTD PMID:10365824 PMID:14623498 PMID:17404311 PMID:18604214 PMID:19130485 PMID:22221676 PMID:23430110 PMID:24149798 PMID:24158569 PMID:24685903 PMID:26068648 PMID:26086368 PMID:26431797 PMID:26586371 PMID:26968431 PMID:27311643 PMID:29960001 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression		 ISO
EXP		 Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; NF157 compound inhibits the reaction [Adenosine Triphosphate results in increased expression of IL6 protein]; sodium arsenite promotes the reaction [Adenosine Triphosphate results in increased expression of IL6 protein]; Suramin inhibits the reaction [Adenosine Triphosphate results in increased expression of IL6 protein]
Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]; coomassie Brilliant Blue inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; resveratrol inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; SB 203580 inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]
azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased expression of IL6 protein]; MRS 2211 inhibits the reaction [Adenosine Triphosphate results in increased expression of IL6 protein]		 CTD PMID:17707769 PMID:24793913 PMID:24849676 PMID:25348860 PMID:26104857 PMID:26522449 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981 		JBrowse link
G Ins1 insulin I multiple interactions EXP Adenosine Triphosphate inhibits the reaction [Glucose results in increased secretion of INS1 protein] CTD PMID:10535451 NCBI chr19:52,264,297...52,265,015
Ensembl chr19:52,264,297...52,265,476 		JBrowse link
G Ins2 insulin II multiple interactions ISO [ammonium ferrous sulfate results in increased activity of INS protein modified form] which results in increased secretion of Adenosine Triphosphate; [chromic chloride results in increased activity of INS protein modified form] which results in increased secretion of Adenosine Triphosphate; INS protein inhibits the reaction [Acetaminophen results in decreased abundance of Adenosine Triphosphate]; Mannose inhibits the reaction [[chromic chloride results in increased activity of INS protein modified form] which results in increased secretion of Adenosine Triphosphate]; Phloretin inhibits the reaction [[chromic chloride results in increased activity of INS protein modified form] which results in increased secretion of Adenosine Triphosphate] CTD PMID:17965850 PMID:26739624 NCBI chr 7:142,678,656...142,679,726
Ensembl chr 7:142,678,656...142,743,381 		JBrowse link
G Itgb1bp2 integrin beta 1 binding protein 2 multiple interactions ISO
EXP		 Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to PPP5C protein]; Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to SUGT1 protein]; Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to SUGT1 protein]]
Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to CHORDC1 protein]; Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]; Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to ITGB1BP2 protein]; Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]]		 CTD PMID:23184943 NCBI chr  X:101,449,088...101,466,122
Ensembl chr  X:101,449,088...101,453,541 		JBrowse link
G Jun jun proto-oncogene multiple interactions ISO [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of JUN protein; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of JUN protein] CTD PMID:24149798 NCBI chr 4:95,049,036...95,052,222
Ensembl chr 4:95,049,034...95,052,222 		JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 decreases activity ISO Adenosine Triphosphate deficiency results in decreased activity of KCNH2 protein CTD PMID:12531891 NCBI chr 5:24,319,589...24,351,684
Ensembl chr 5:24,319,589...24,351,604 		JBrowse link
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 multiple interactions
decreases response to substance		 EXP Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]; Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]; Creatine metabolite inhibits the reaction [Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]]
KCNJ11 protein mutant form results in decreased susceptibility to Adenosine Triphosphate		 CTD PMID:11390963 PMID:28842488 NCBI chr 7:46,097,123...46,100,952
Ensembl chr 7:46,093,953...46,100,764 		JBrowse link
G Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 increases activity ISO Adenosine Triphosphate results in increased activity of KCNJ15 protein CTD PMID:15328350 NCBI chr16:95,257,558...95,300,260
Ensembl chr16:95,257,558...95,300,260 		JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 decreases response to substance
multiple interactions		 ISO KCNJ8 protein mutant form results in decreased susceptibility to Adenosine Triphosphate
Adenosine Triphosphate results in decreased activity of [KCNJ8 protein binds to ABCC9 protein]		 CTD PMID:28842488 NCBI chr 6:142,564,837...142,571,614
Ensembl chr 6:142,564,837...142,571,614 		JBrowse link
G Khk ketohexokinase multiple interactions ISO KHK protein promotes the reaction [Fructose results in decreased abundance of Adenosine Triphosphate] CTD PMID:19158351 NCBI chr 5:30,921,436...30,931,248
Ensembl chr 5:30,921,431...30,931,248 		JBrowse link
G Kif5a kinesin family member 5A multiple interactions
increases hydrolysis		 ISO Adenosine Triphosphate inhibits the reaction [zinc chloride results in decreased activity of KIF5A protein]; Cadmium Chloride inhibits the reaction [KIF5A protein results in increased hydrolysis of Adenosine Triphosphate]; Egtazic Acid inhibits the reaction [Cadmium Chloride inhibits the reaction [KIF5A protein results in increased hydrolysis of Adenosine Triphosphate]] CTD PMID:24239783 PMID:28122263 NCBI chr10:127,225,695...127,266,348
Ensembl chr10:127,225,696...127,263,348 		JBrowse link
G Lep leptin multiple interactions ISO [[Glucose co-treated with INS1 protein] results in increased abundance of Adenosine Triphosphate] which results in increased secretion of LEP protein; [Deoxyglucose results in decreased abundance of Adenosine Triphosphate] which results in decreased secretion of LEP protein CTD PMID:10780946 NCBI chr 6:29,060,221...29,073,876
Ensembl chr 6:29,060,220...29,073,877 		JBrowse link
G Lipe lipase, hormone sensitive increases activity ISO Adenosine Triphosphate results in increased activity of LIPE protein CTD PMID:7155675 NCBI chr 7:25,379,527...25,398,486
Ensembl chr 7:25,379,527...25,398,710 		JBrowse link
G Lpl lipoprotein lipase affects response to substance ISO LPL protein affects the susceptibility to Adenosine Triphosphate CTD PMID:11786490 NCBI chr 8:68,880,555...68,906,932
Ensembl chr 8:68,880,491...68,907,448 		JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 affects binding EXP Adenosine Triphosphate binds to MAP2K1 protein CTD PMID:17693661 NCBI chr 9:64,185,769...64,253,605
Ensembl chr 9:64,185,770...64,253,631 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation
increases activity		 ISO
EXP		 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Adenosine Triphosphate results in increased phosphorylation of MAPK1 protein]; [Alcohols co-treated with Adenosine Triphosphate] results in increased activity of MAPK1 protein; Alcohols inhibits the reaction [Adenosine Triphosphate results in increased activity of MAPK1 protein]; sodium arsenite promotes the reaction [Adenosine Triphosphate results in increased phosphorylation of MAPK1 protein]
azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased phosphorylation of MAPK1 protein]		 CTD PMID:12513686 PMID:15034929 PMID:21503959 PMID:24300283 PMID:26104857 PMID:26522449 PMID:30502331 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation
increases activity		 ISO
EXP		 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Adenosine Triphosphate results in increased phosphorylation of MAPK3 protein]; [Alcohols co-treated with Adenosine Triphosphate] results in increased activity of MAPK3 protein; Alcohols inhibits the reaction [Adenosine Triphosphate results in increased activity of MAPK3 protein]; sodium arsenite promotes the reaction [Adenosine Triphosphate results in increased phosphorylation of MAPK3 protein]
azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased phosphorylation of MAPK3 protein]		 CTD PMID:12513686 PMID:15034929 PMID:21503959 PMID:24300283 PMID:26104857 PMID:26522449 PMID:30502331 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819 		JBrowse link
G Mapt microtubule-associated protein tau multiple interactions ISO [annonacin results in decreased abundance of Adenosine Triphosphate] which affects the localization of MAPT protein CTD PMID:17634376 NCBI chr11:104,229,409...104,332,090
Ensembl chr11:104,231,390...104,332,090 		JBrowse link
G Metrnl meteorin, glial cell differentiation regulator-like multiple interactions EXP METRNL protein inhibits the reaction [Dietary Fats results in decreased abundance of Adenosine Triphosphate] CTD PMID:30213948 NCBI chr11:121,702,427...121,717,389
Ensembl chr11:121,701,544...121,716,306 		JBrowse link
G Mfn2 mitofusin 2 decreases response to substance
multiple interactions
increases chemical synthesis		 EXP
ISO		 MFN2 results in decreased susceptibility to Adenosine Triphosphate deficiency
MFN2 protein inhibits the reaction [TNF protein results in decreased chemical synthesis of Adenosine Triphosphate]
MFN2 protein results in increased chemical synthesis of Adenosine Triphosphate
MFN2 protein inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased chemical synthesis of Adenosine Triphosphate]		 CTD PMID:22292091 PMID:24898700 PMID:25416777 NCBI chr 4:147,873,586...147,904,909
Ensembl chr 4:147,873,599...147,904,704 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases activity
increases secretion		 ISO
EXP		 1,10-phenanthroline inhibits the reaction [Adenosine Triphosphate results in increased activity of MMP9 protein]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Adenosine Triphosphate results in increased activity of MMP9 protein]; SB 3CT compound inhibits the reaction [Adenosine Triphosphate results in increased activity of MMP9 protein]; wortmannin inhibits the reaction [Adenosine Triphosphate results in increased activity of MMP9 protein]
azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased expression of MMP9 protein]
Adenosine Triphosphate results in increased secretion of MMP9 protein		 CTD PMID:20195827 PMID:26522449 NCBI chr 2:164,940,326...164,955,850
Ensembl chr 2:164,940,780...164,955,850 		JBrowse link
G mt-Atp6 ATP synthase 6, mitochondrial affects abundance ISO ATP6 protein affects the abundance of Adenosine Triphosphate CTD PMID:18273840 NCBI chr MT:7,927...8,607
Ensembl chr MT:7,927...8,607 		JBrowse link
G mt-Co3 cytochrome c oxidase III, mitochondrial increases abundance ISO COX3 protein results in increased abundance of Adenosine Triphosphate CTD PMID:17428446 NCBI chr MT:8,607...9,390
Ensembl chr MT:8,607...9,390 		JBrowse link
G Mvd mevalonate (diphospho) decarboxylase increases hydrolysis ISO MVD protein results in increased hydrolysis of Adenosine Triphosphate CTD PMID:9392419 NCBI chr 8:122,433,596...122,443,422
Ensembl chr 8:122,433,601...122,443,422 		JBrowse link
G Mvk mevalonate kinase multiple interactions
increases hydrolysis		 ISO 3,3-dimethylallyl pyrophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; dolichol monophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; Farnesol inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; farnesyl pyrophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; geranyl diphosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; geranylgeranyl pyrophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; isopentenyl pyrophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate] CTD PMID:9392419 NCBI chr 5:114,444,264...114,460,591
Ensembl chr 5:114,444,269...114,460,591 		JBrowse link
G Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta increases abundance ISO MYH7 gene mutant form results in increased abundance of Adenosine Triphosphate CTD PMID:29741611 NCBI chr14:54,970,684...54,994,626
Ensembl chr14:54,970,684...54,994,626 		JBrowse link
G Nadsyn1 NAD synthetase 1 multiple interactions ISO [Ammonium Chloride co-treated with nicotinic acid adenine dinucleotide co-treated with Adenosine Triphosphate] results in increased activity of NADSYN1 protein; [NADSYN1 protein co-treated with Ammonium Chloride co-treated with nicotinic acid adenine dinucleotide co-treated with Adenosine Triphosphate] results in increased chemical synthesis of NAD CTD PMID:12547821 NCBI chr 7:143,795,589...143,822,862
Ensembl chr 7:143,795,584...143,822,849 		JBrowse link
G Ncs1 neuronal calcium sensor 1 multiple interactions
increases response to substance		 ISO NCS1 protein promotes the reaction [Adenosine Triphosphate results in increased secretion of GH1 protein]; oxophenylarsine inhibits the reaction [NCS1 protein promotes the reaction [Adenosine Triphosphate results in increased secretion of GH1 protein]]
NCS1 protein results in increased susceptibility to Adenosine Triphosphate		 CTD PMID:12471042 NCBI chr 2:31,245,708...31,295,989
Ensembl chr 2:31,245,823...31,295,989 		JBrowse link
G Nfatc1 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 affects localization
multiple interactions		 ISO
EXP		 Adenosine Triphosphate affects the localization of NFATC1 protein
azetidine analog inhibits the reaction [Adenosine Triphosphate affects the localization of NFATC1 protein]		 CTD PMID:21464294 PMID:26522449 NCBI chr18:80,606,205...80,713,071
Ensembl chr18:80,606,205...80,713,071 		JBrowse link
G Nfatc3 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3 affects localization ISO Adenosine Triphosphate affects the localization of NFATC3 protein CTD PMID:21464294 NCBI chr 8:106,058,818...106,130,537
Ensembl chr 8:106,058,840...106,130,537 		JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions ISO Adenosine Triphosphate promotes the reaction [RELA protein binds to NFKBIA protein]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to NFKBIA protein]]
[Adenosine Triphosphate co-treated with Lipopolysaccharides] affects the localization of NFKBIA protein; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] affects the localization of NFKBIA protein]		 CTD PMID:21464294 PMID:24149798 NCBI chr12:55,489,409...55,492,647
Ensembl chr12:55,489,410...55,492,647 		JBrowse link
G Ngf nerve growth factor multiple interactions ISO [NGF protein co-treated with Adenosine Triphosphate] results in increased uptake of Calcium CTD PMID:1374475 NCBI chr 3:102,469,919...102,521,013
Ensembl chr 3:102,469,919...102,521,013 		JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A multiple interactions ISO [Lipopolysaccharides co-treated with Adenosine Triphosphate co-treated with resveratrol] results in increased expression of NLRP1 mRNA CTD PMID:24149798 NCBI chr11:71,091,197...71,144,969
Ensembl chr11:71,092,236...71,144,704 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO
EXP		 [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased activity of NLRP3 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate co-treated with resveratrol] results in increased expression of NLRP3 mRNA; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 mRNA; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein; KN 62 inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]
[Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to CASP1 protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PML protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PYCARD protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of and results in increased cleavage of IL1B protein]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to CASP1 protein]]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PYCARD protein]]		 CTD PMID:18604214 PMID:23430110 PMID:24149798 PMID:26086368 PMID:26586371 NCBI chr11:59,541,569...59,566,955
Ensembl chr11:59,541,568...59,566,956 		JBrowse link
G Nolc1 nucleolar and coiled-body phosphoprotein 1 multiple interactions ISO Adenosine Triphosphate affects the reaction [Doxorubicin binds to NOLC1 protein] CTD PMID:17129415 NCBI chr19:46,075,847...46,085,543
Ensembl chr19:46,075,863...46,085,530 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions
increases expression		 ISO
EXP		 NOS2 protein affects the reaction [Adenosine Triphosphate results in increased metabolism of RELA protein]
azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased expression of NOS2 protein]
[Adenosine Triphosphate results in increased expression of NOS2 protein] promotes the reaction [NOS2 protein binds to RELA protein]; Adenosine Triphosphate promotes the reaction [RELA protein binds to NOS2 protein]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to NOS2 protein]]; Cyclosporine inhibits the reaction [[Adenosine Triphosphate results in increased expression of NOS2 protein] promotes the reaction [NOS2 protein binds to RELA protein]]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Adenosine Triphosphate results in increased expression of NOS2 protein]; NOS2 protein affects the reaction [Adenosine Triphosphate results in increased abundance of Nitric Oxide]		 CTD PMID:21464294 PMID:26522449 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell multiple interactions ISO Adenosine Triphosphate affects the reaction [Alcohols affects the phosphorylation of NOS3 protein]; Adenosine Triphosphate inhibits the reaction [Alcohols results in decreased expression of NOS3 protein] CTD PMID:24300283 NCBI chr 5:24,364,816...24,384,474
Ensembl chr 5:24,364,810...24,384,474 		JBrowse link
G Npy neuropeptide Y affects response to substance ISO NPY protein affects the susceptibility to Adenosine Triphosphate CTD PMID:15003356 NCBI chr 6:49,822,710...49,829,507
Ensembl chr 6:49,822,710...49,829,507 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 increases expression ISO Adenosine Triphosphate results in increased expression of NR4A1 mRNA CTD PMID:10723097 NCBI chr15:101,253,902...101,274,795
Ensembl chr15:101,254,269...101,274,795 		JBrowse link
G Oas1g 2'-5' oligoadenylate synthetase 1G multiple interactions ISO [OAS1 protein results in increased metabolism of Adenosine Triphosphate] which results in increased chemical synthesis of 2',5'-oligoadenylate CTD PMID:15732009 NCBI chr 5:120,876,142...120,887,613
Ensembl chr 5:120,876,142...120,887,613 		JBrowse link
G Oxt oxytocin multiple interactions
increases secretion		 ISO Adenosine Triphosphate promotes the reaction [Phenylephrine results in increased secretion of OXT protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of OXT protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased secretion of OXT protein] CTD PMID:11102496 NCBI chr 2:130,574,519...130,577,054
Ensembl chr 2:130,576,173...130,577,054 		JBrowse link
G P2rx1 purinergic receptor P2X, ligand-gated ion channel, 1 multiple interactions ISO geldanamycin promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX1]; herbimycin promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX1]; monorden promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX1] CTD PMID:11930156 NCBI chr11:72,999,056...73,015,200
Ensembl chr11:72,999,103...73,015,200 		JBrowse link
G P2rx2 purinergic receptor P2X, ligand-gated ion channel, 2 multiple interactions
increases activity
affects response to substance		 ISO
EXP		 1-amino-4-(3-(4,6-dichloro(1,3,5)triazine-2-ylamino)phenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]]; Acetylcysteine inhibits the reaction [Rotenone promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]]; Cadmium Chloride affects the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; cobaltous chloride affects the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; Copper promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; cupric chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; Dithiothreitol inhibits the reaction [Hydrogen Peroxide promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]]; Hydrogen Peroxide promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; Mercuric Chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; Mercury promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; methyl methanethiosulfonate inhibits the reaction [Hydrogen Peroxide promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]]; methyl methanethiosulfonate inhibits the reaction [Mercury promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]]; myxothiazol promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; nickel chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; palladium chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; Rotenone promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; zinc chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; Zinc promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]
P2RX2 protein affects the susceptibility to Adenosine Triphosphate		 CTD PMID:15081800 PMID:16190872 PMID:19793987 PMID:21207957 NCBI chr 5:110,339,812...110,343,320
Ensembl chr 5:110,339,812...110,343,212 		JBrowse link
G P2rx3 purinergic receptor P2X, ligand-gated ion channel, 3 multiple interactions
affects activity		 ISO Eugenol inhibits the reaction [P2RX3 protein affects the activity of Adenosine Triphosphate] CTD PMID:19967073 NCBI chr 2:84,996,549...85,037,108
Ensembl chr 2:84,998,583...85,037,462 		JBrowse link
G P2rx4 purinergic receptor P2X, ligand-gated ion channel 4 multiple interactions
increases activity		 ISO
EXP		 [Cadmium co-treated with Zinc] promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; [Mercury co-treated with Copper] inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; Cadmium promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; Cobalt promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; Copper inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; Copper inhibits the reaction [Zinc promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]]; Mercury inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; Zinc promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]
5-(3-bromophenyl)-1,3-dihydro-2H-benzofuro(3,2-e)-1,4-diazepin-2-one inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; [ginsenoside M1 co-treated with Adenosine Triphosphate] results in increased activity of P2RX4 protein; [Resveratrol co-treated with Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX4 mRNA; [Resveratrol co-treated with Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX4 protein; ginsenoside M1 promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; ginsenoside Rb1 promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; ginsenoside Rd promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; Ivermectin promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]		 CTD PMID:10737610 PMID:15629187 PMID:19793987 PMID:21638035 PMID:24149798 PMID:30545933 NCBI chr 5:122,707,518...122,729,739
Ensembl chr 5:122,707,544...122,729,738 		JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 multiple interactions
increases expression
decreases response to substance
increases response to substance
increases activity		 ISO
EXP		 [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 mRNA; [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 protein; AZ10606120 inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein]; P2RX7 protein affects the reaction [Adenosine Triphosphate results in increased secretion of SELL protein]; P2RX7 protein affects the reaction [Adenosine Triphosphate results in increased transport of Barium]; Resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 mRNA]; Resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 protein]
Adenosine Triphosphate results in increased expression of P2RX7 protein
P2RX7 gene mutant form results in decreased susceptibility to Adenosine Triphosphate
P2RX7 protein results in increased susceptibility to Adenosine Triphosphate
3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein]; azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased expression of P2RX7 protein]; coomassie Brilliant Blue inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein]		 CTD PMID:11003599 PMID:17728465 PMID:19023039 PMID:21638035 PMID:23565201 PMID:24101734 PMID:24149798 PMID:26522449 PMID:27466191 PMID:30545933 PMID:31504961 NCBI chr 5:122,643,927...122,692,336
Ensembl chr 5:122,643,911...122,691,432 		JBrowse link
G P2ry1 purinergic receptor P2Y, G-protein coupled 1 multiple interactions
affects activity		 ISO
EXP		 [Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein] which results in increased abundance of Calcium; Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate inhibits the reaction [P2RY1 protein promotes the reaction [Adenosine Triphosphate results in decreased susceptibility to Hydrogen Peroxide]]; P2RY1 protein promotes the reaction [Adenosine Triphosphate results in decreased susceptibility to Hydrogen Peroxide]; Trichloroethylene inhibits the reaction [[Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein] which results in increased abundance of Calcium]
[N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate binds to and results in decreased activity of P2RY1 protein] inhibits the reaction [Adenosine Triphosphate results in increased uptake of Calcium]
Adenosine Triphosphate affects the activity of P2RY1 protein		 CTD PMID:12694404 PMID:15243297 PMID:16973929 PMID:22129738 NCBI chr 3:61,002,785...61,008,982
Ensembl chr 3:61,002,795...61,008,982 		JBrowse link
G P2ry13 purinergic receptor P2Y, G-protein coupled 13 multiple interactions ISO MRS 2211 inhibits the reaction [P2RY13 protein promotes the reaction [Adenosine Triphosphate results in decreased susceptibility to Hydrogen Peroxide]]; P2RY13 protein promotes the reaction [Adenosine Triphosphate results in decreased susceptibility to Hydrogen Peroxide] CTD PMID:22129738 NCBI chr 3:59,207,892...59,210,882
Ensembl chr 3:59,207,892...59,210,882 		JBrowse link
G P2ry2 purinergic receptor P2Y, G-protein coupled 2 multiple interactions
affects activity
increases activity		 ISO
EXP		 [Adenosine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Calcium
[Adenosine Triphosphate results in increased activity of P2RY2 protein] which results in increased uptake of Calcium
Adenosine Triphosphate affects the activity of P2RY2 protein		 CTD PMID:11527950 PMID:15243297 PMID:17003265 NCBI chr 7:100,996,568...101,012,053
Ensembl chr 7:100,996,568...101,012,866 		JBrowse link
G P2ry4 pyrimidinergic receptor P2Y, G-protein coupled, 4 multiple interactions ISO [Adenosine Triphosphate binds to and results in increased activity of P2RY4 protein] which results in increased abundance of Calcium; Adenosine Triphosphate binds to and results in increased activity of P2RY4 protein; Trichloroethylene inhibits the reaction [[Adenosine Triphosphate binds to and results in increased activity of P2RY4 protein] which results in increased abundance of Calcium] CTD PMID:12694404 NCBI chr  X:100,588,358...100,594,927
Ensembl chr  X:100,590,154...100,594,869 		JBrowse link
G P2ry6 pyrimidinergic receptor P2Y, G-protein coupled, 6 multiple interactions ISO N,N''-1,4-butanediylbis(N'-(3-isothiocyanatophenyl))thiourea inhibits the reaction [P2RY6 protein promotes the reaction [Adenosine Triphosphate results in decreased susceptibility to Hydrogen Peroxide]]; P2RY6 protein promotes the reaction [Adenosine Triphosphate results in decreased susceptibility to Hydrogen Peroxide] CTD PMID:22129738 NCBI chr 7:100,937,630...100,975,498
Ensembl chr 7:100,937,630...100,974,649 		JBrowse link
G Panx1 pannexin 1 decreases activity
multiple interactions
increases export		 ISO
EXP		 Adenosine Triphosphate results in decreased activity of PANX1 protein
Carbenoxolone inhibits the reaction [PANX1 protein results in increased export of Adenosine Triphosphate]; Probenecid inhibits the reaction [PANX1 protein results in increased export of Adenosine Triphosphate]		 CTD PMID:19023039 PMID:19213873 NCBI chr 9:15,005,785...15,045,478
Ensembl chr 9:15,002,128...15,045,478 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions
increases expression		 ISO
EXP		 PARP1 mutant form inhibits the reaction [Cadmium results in decreased abundance of Adenosine Triphosphate]
PARP1 protein affects the reaction [pyrithione zinc results in decreased abundance of Adenosine Triphosphate]; PARP1 protein affects the reaction [Zinc results in decreased abundance of Adenosine Triphosphate]
Adenosine Triphosphate results in increased expression of PARP1 protein		 CTD PMID:17728843 PMID:19809895 PMID:21767558 PMID:22253048 NCBI chr 1:180,568,891...180,600,999
Ensembl chr 1:180,568,924...180,601,254 		JBrowse link
G Pdk1 pyruvate dehydrogenase kinase, isoenzyme 1 multiple interactions
affects response to substance		 EXP [PDK1 protein affects the susceptibility to Adenosine Triphosphate] which affects the abundance of Calcium; Adenosine Triphosphate promotes the reaction [PDK1 protein affects the abundance of Calcium]; tubacin affects the reaction [[PDK1 protein affects the susceptibility to Adenosine Triphosphate] which affects the abundance of Calcium] CTD PMID:28887310 NCBI chr 2:71,873,215...71,903,858
Ensembl chr 2:71,873,224...71,903,858 		JBrowse link
G Pfkm phosphofructokinase, muscle multiple interactions ISO Adenosine Triphosphate promotes the reaction [resveratrol results in decreased activity of PFKM protein] CTD PMID:23454376 NCBI chr15:98,092,589...98,132,447
Ensembl chr15:98,092,589...98,132,451 		JBrowse link
G Pgp phosphoglycolate phosphatase decreases phosphorylation EXP PGP protein results in decreased phosphorylation of Adenosine Triphosphate CTD PMID:24338473 NCBI chr17:24,470,426...24,473,110
Ensembl chr17:24,470,392...24,473,110 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha multiple interactions
affects binding		 ISO 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine inhibits the reaction [Adenosine Triphosphate binds to PIK3CA protein]; Adenosine Triphosphate inhibits the reaction [resveratrol results in decreased activity of [PIK3R1 protein binds to PIK3CA protein]] CTD PMID:17550345 PMID:18754654 NCBI chr 3:32,397,065...32,466,112
Ensembl chr 3:32,397,671...32,468,486 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions ISO Adenosine Triphosphate inhibits the reaction [resveratrol results in decreased activity of [PIK3R1 protein binds to PIK3CA protein]] CTD PMID:17550345 NCBI chr13:101,680,761...101,768,217
Ensembl chr13:101,680,563...101,768,217 		JBrowse link
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) increases activity EXP Adenosine Triphosphate results in increased activity of PLA2G4A protein CTD PMID:10535451 NCBI chr 1:149,829,618...149,961,290
Ensembl chr 1:149,829,618...149,961,290 		JBrowse link
G Plau plasminogen activator, urokinase increases secretion EXP Adenosine Triphosphate results in increased secretion of PLAU protein CTD PMID:20177776 NCBI chr14:20,836,662...20,843,388
Ensembl chr14:20,836,660...20,843,385 		JBrowse link
G Plpp3 phospholipid phosphatase 3 decreases chemical synthesis EXP PLPP3 gene mutant form results in decreased chemical synthesis of Adenosine Triphosphate CTD PMID:28982073 NCBI chr 4:105,157,347...105,232,767
Ensembl chr 4:105,157,347...105,232,764 		JBrowse link
G Pml promyelocytic leukemia multiple interactions EXP [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PML protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [PML protein binds to CASP1 protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of PML protein; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to CASP1 protein]]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PYCARD protein]]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased abundance of Reactive Oxygen Species]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; PML protein promotes the reaction [[resiquimod co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein] CTD PMID:23430110 NCBI chr 9:58,217,179...58,249,796
Ensembl chr 9:58,218,076...58,249,786 		JBrowse link
G Pmvk phosphomevalonate kinase increases hydrolysis ISO PMVK protein results in increased hydrolysis of Adenosine Triphosphate CTD PMID:9392419 NCBI chr 3:89,454,541...89,469,014
Ensembl chr 3:89,454,541...89,469,013 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP [Fenofibrate results in increased activity of PPARA protein] which results in decreased abundance of Adenosine Triphosphate CTD PMID:19593819 NCBI chr15:85,734,910...85,806,851
Ensembl chr15:85,734,983...85,802,819 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions
decreases abundance		 ISO FASN protein promotes the reaction [rosiglitazone promotes the reaction [PPARG protein results in decreased abundance of Adenosine Triphosphate]]; rosiglitazone promotes the reaction [PPARG protein results in decreased abundance of Adenosine Triphosphate]; UCP1 protein promotes the reaction [PPARG protein mutant form results in decreased abundance of Adenosine Triphosphate]; UCP1 protein promotes the reaction [rosiglitazone promotes the reaction [PPARG protein results in decreased abundance of Adenosine Triphosphate]]
PPARG protein mutant form results in decreased abundance of Adenosine Triphosphate; PPARG protein results in decreased abundance of Adenosine Triphosphate		 CTD PMID:26670611 NCBI chr 6:115,360,879...115,490,404
Ensembl chr 6:115,360,951...115,490,399 		JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit multiple interactions ISO Adenosine Triphosphate binds to and affects the folding of PPP5C protein; Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to PPP5C protein]; Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to PPP5C protein] CTD PMID:23184943 NCBI chr 7:17,004,640...17,027,914
Ensembl chr 7:17,004,640...17,027,924 		JBrowse link
G Prdx2 peroxiredoxin 2 increases expression ISO Adenosine Triphosphate results in increased expression of PRDX2 protein modified form CTD PMID:16178011 NCBI chr 8:84,969,622...84,974,811
Ensembl chr 8:84,969,587...84,974,834 		JBrowse link
G Prkca protein kinase C, alpha multiple interactions ISO [[Adenosine Triphosphate co-treated with PRKCA protein] results in increased phosphorylation of RALBP1 protein] which results in increased transport of Doxorubicin CTD PMID:16087181 NCBI chr11:107,933,387...108,343,888
Ensembl chr11:107,933,387...108,343,928 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of PTGS2 protein; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of PTGS2 protein] CTD PMID:24149798 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227 		JBrowse link
G Pycard PYD and CARD domain containing multiple interactions ISO
EXP		 [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in decreased expression of PYCARD mRNA; resveratrol inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in decreased expression of PYCARD mRNA]
[Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PYCARD protein]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PYCARD protein]]; PYCARD gene mutant form inhibits the reaction [Adenosine Triphosphate results in increased abundance of G(M3) Ganglioside]; PYCARD protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]; PYCARD protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of and results in increased cleavage of IL1B protein]		 CTD PMID:18604214 PMID:23430110 PMID:24149798 PMID:24475307 NCBI chr 7:127,991,373...127,993,867
Ensembl chr 7:127,989,708...127,993,867 		JBrowse link
G Ralbp1 ralA binding protein 1 multiple interactions ISO [[Adenosine Triphosphate co-treated with PRKCA protein] results in increased phosphorylation of RALBP1 protein] which results in increased transport of Doxorubicin; Adenosine Triphosphate promotes the reaction [RALBP1 protein affects the transport of Leukotriene C4] CTD PMID:15386349 PMID:16087181 NCBI chr17:65,848,415...65,885,755
Ensembl chr17:65,848,418...65,885,798 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO [Adenosine Triphosphate results in increased expression of NOS2 protein] promotes the reaction [NOS2 protein binds to RELA protein]; Adenosine Triphosphate promotes the reaction [RELA protein binds to ARRB2 protein]; Adenosine Triphosphate promotes the reaction [RELA protein binds to NFKBIA protein]; Adenosine Triphosphate promotes the reaction [RELA protein binds to NOS2 protein]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to ARRB2 protein]]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to NFKBIA protein]]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to NOS2 protein]]; Cyclosporine inhibits the reaction [[Adenosine Triphosphate results in increased expression of NOS2 protein] promotes the reaction [NOS2 protein binds to RELA protein]]
[Adenosine Triphosphate co-treated with Lipopolysaccharides] affects the localization of RELA protein; NOS2 protein affects the reaction [Adenosine Triphosphate results in increased metabolism of RELA protein]; resveratrol promotes the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] affects the localization of RELA protein]; S-Nitrosoglutathione promotes the reaction [Adenosine Triphosphate results in increased metabolism of RELA protein]		 CTD PMID:21464294 PMID:24149798 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130 		JBrowse link
G Rhof ras homolog family member F (in filopodia) increases expression
multiple interactions		 ISO
EXP		 Adenosine Triphosphate results in increased expression of RHOF mRNA
Niclosamide inhibits the reaction [Adenosine Triphosphate results in increased expression of RHOF mRNA]		 CTD PMID:29733962 NCBI chr 5:123,118,180...123,141,808
Ensembl chr 5:123,103,044...123,132,692 		JBrowse link
G S100a10 S100 calcium binding protein A10 (calpactin) increases expression ISO Adenosine Triphosphate results in increased expression of S100A10 mRNA CTD PMID:29733962 NCBI chr 3:93,555,117...93,564,645
Ensembl chr 3:93,555,080...93,564,643 		JBrowse link
G S100a11 S100 calcium binding protein A11 increases expression ISO Adenosine Triphosphate results in increased expression of S100A11 mRNA CTD PMID:29733962 NCBI chr 3:93,520,496...93,526,288
Ensembl chr 3:93,520,488...93,526,287 		JBrowse link
G S100a4 S100 calcium binding protein A4 multiple interactions
increases expression		 EXP
ISO		 Adenosine Triphosphate results in increased expression of and results in increased secretion of S100A4 protein; Niclosamide inhibits the reaction [Adenosine Triphosphate results in increased expression of S100A4 protein]
Adenosine Triphosphate results in increased expression of S100A4 mRNA		 CTD PMID:29733962 NCBI chr 3:90,603,770...90,606,045
Ensembl chr 3:90,603,771...90,606,045 		JBrowse link
G S100a6 S100 calcium binding protein A6 (calcyclin) increases expression ISO Adenosine Triphosphate results in increased expression of S100A6 mRNA CTD PMID:29733962 NCBI chr 3:90,612,894...90,614,414
Ensembl chr 3:90,612,882...90,624,181 		JBrowse link
G Sell selectin, lymphocyte multiple interactions ISO P2RX7 protein affects the reaction [Adenosine Triphosphate results in increased secretion of SELL protein] CTD PMID:11003599 NCBI chr 1:164,061,987...164,082,930
Ensembl chr 1:164,061,982...164,084,181 		JBrowse link
G Sftpa1 surfactant associated protein A1 multiple interactions ISO [SFTPA1 protein polymorphism binds to SFTPA2 protein polymorphism] inhibits the reaction [Adenosine Triphosphate results in increased secretion of Phosphatidylcholines]; Ozone inhibits the reaction [[SFTPA1 protein polymorphism binds to SFTPA2 protein polymorphism] inhibits the reaction [Adenosine Triphosphate results in increased secretion of Phosphatidylcholines]]; Ozone inhibits the reaction [SFTPA1 protein polymorphism inhibits the reaction [Adenosine Triphosphate results in increased secretion of Phosphatidylcholines]] CTD PMID:15065867 NCBI chr14:41,131,788...41,136,373
Ensembl chr14:41,131,782...41,136,452 		JBrowse link
G Sftpb surfactant associated protein B increases secretion
multiple interactions		 EXP
ISO		 Adenosine Triphosphate results in increased secretion of SFTPB protein
Ro 31-8220 inhibits the reaction [Adenosine Triphosphate results in increased secretion of SFTPB protein]		 CTD PMID:11704537 PMID:14565945 NCBI chr 6:72,304,610...72,314,373
Ensembl chr 6:72,304,610...72,314,371 		JBrowse link
G Sftpc surfactant associated protein C increases secretion
multiple interactions		 ISO
EXP		 Adenosine Triphosphate results in increased secretion of SFTPC protein
Ro 31-8220 inhibits the reaction [Adenosine Triphosphate results in increased secretion of SFTPC protein]		 CTD PMID:11704537 PMID:14565945 NCBI chr14:70,520,941...70,524,081
Ensembl chr14:70,520,949...70,524,081 		JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO [SIRT1 protein results in decreased expression of UCP2 mRNA] promotes the reaction [Glucose results in increased abundance of Adenosine Triphosphate]; SIRT1 protein promotes the reaction [[Glucose results in increased abundance of Adenosine Triphosphate] which results in increased expression of INS1 protein]; SIRT1 protein promotes the reaction [Glucose results in increased abundance of Adenosine Triphosphate] CTD PMID:16366736 NCBI chr10:63,319,005...63,339,035
Ensembl chr10:63,319,005...63,381,704 		JBrowse link
G Sirt3 sirtuin 3 multiple interactions EXP SIRT3 protein inhibits the reaction [Metformin results in decreased abundance of Adenosine Triphosphate] CTD PMID:23166782 NCBI chr 7:140,863,663...140,882,309
Ensembl chr 7:140,863,666...140,882,309 		JBrowse link
G Slc25a14 solute carrier family 25 (mitochondrial carrier, brain), member 14 decreases chemical synthesis ISO SLC25A14 protein results in decreased chemical synthesis of Adenosine Triphosphate CTD PMID:20600837 NCBI chr  X:48,623,418...48,662,298
Ensembl chr  X:48,623,413...48,662,294 		JBrowse link
G Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 decreases stability ISO Adenosine Triphosphate results in decreased stability of SLC2A1 protein CTD PMID:11420438 NCBI chr 4:119,108,745...119,137,330
Ensembl chr 4:119,108,711...119,137,983 		JBrowse link
G Slc46a1 solute carrier family 46, member 1 multiple interactions ISO [SLC46A1 protein results in increased susceptibility to N-((5-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo(2,3-d)pyrimidin-6-yl)propyl)thiophen-2-yl)carbonyl)glutamic acid] which results in decreased chemical synthesis of Adenosine Triphosphate CTD PMID:21879757 NCBI chr11:78,465,701...78,471,945
Ensembl chr11:78,465,697...78,472,059 		JBrowse link
G Slc5a5 solute carrier family 5 (sodium iodide symporter), member 5 multiple interactions ISO Adenosine Triphosphate inhibits the reaction [TSHB protein results in increased expression of SLC5A5 protein] CTD PMID:16439463 NCBI chr 8:70,882,885...70,892,785
Ensembl chr 8:70,882,889...70,892,757 		JBrowse link
G Snca synuclein, alpha multiple interactions
decreases abundance		 ISO GW8510 inhibits the reaction [SNCA protein results in decreased abundance of Adenosine Triphosphate]; SB 216763 inhibits the reaction [SNCA protein results in decreased abundance of Adenosine Triphosphate] CTD PMID:24989254 NCBI chr 6:60,731,573...60,829,855
Ensembl chr 6:60,731,575...60,829,855 		JBrowse link
G Sod1 superoxide dismutase 1, soluble increases expression ISO Adenosine Triphosphate results in increased expression of SOD1 protein CTD PMID:16178011 PMID:22129738 NCBI chr16:90,220,762...90,226,333
Ensembl chr16:90,220,754...90,226,329 		JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial affects chemical synthesis
decreases abundance
multiple interactions		 EXP SOD2 protein affects the chemical synthesis of Adenosine Triphosphate
SOD2 gene mutant form results in decreased abundance of Adenosine Triphosphate
MK-886 promotes the reaction [SOD2 gene mutant form results in decreased abundance of Adenosine Triphosphate]		 CTD PMID:20638473 PMID:25362851 NCBI chr17:13,007,839...13,018,119
Ensembl chr17:13,006,846...13,040,063 		JBrowse link
G Stxbp2 syntaxin binding protein 2 multiple interactions EXP STXBP2 protein affects the reaction [F2 protein results in increased transport of Adenosine Triphosphate] CTD PMID:30696774 NCBI chr 8:3,630,960...3,643,998
Ensembl chr 8:3,630,955...3,643,644 		JBrowse link
G Sugt1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) multiple interactions ISO Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to SUGT1 protein]; Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to SUGT1 protein]; Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to SUGT1 protein]] CTD PMID:23184943 NCBI chr14:79,587,660...79,630,797
Ensembl chr14:79,587,691...79,635,196 		JBrowse link
G Syn2 synapsin II multiple interactions EXP SYN2 mutant form inhibits the reaction [Adenosine Triphosphate results in increased abundance of Calcium] CTD PMID:18701217 NCBI chr 6:115,134,902...115,282,626
Ensembl chr 6:115,134,902...115,282,006 		JBrowse link
G Tac1 tachykinin 1 increases secretion
multiple interactions		 ISO Adenosine Triphosphate results in increased secretion of TAC1 protein
Iloprost promotes the reaction [Adenosine Triphosphate results in increased secretion of TAC1 protein]		 CTD PMID:16039053 NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834 		JBrowse link
G Taldo1 transaldolase 1 increases abundance EXP TALDO1 gene mutant form results in increased abundance of Adenosine Triphosphate CTD PMID:19436114 NCBI chr 7:141,392,160...141,402,976
Ensembl chr 7:141,392,199...141,402,968 		JBrowse link
G Tas2r115 taste receptor, type 2, member 115 increases activity EXP Adenosine Triphosphate results in increased activity of TAS2R115 protein CTD PMID:29347925 NCBI chr 6:132,737,054...132,737,986
Ensembl chr 6:132,737,003...132,738,035 		JBrowse link
G Tas2r131 taste receptor, type 2, member 131 increases activity EXP Adenosine Triphosphate results in increased activity of TAS2R131 protein CTD PMID:29347925 NCBI chr 6:132,956,912...132,957,844
Ensembl chr 6:132,956,884...132,957,919 		JBrowse link
G Tas2r143 taste receptor, type 2, member 143 increases activity EXP Adenosine Triphosphate results in increased activity of TAS2R143 protein CTD PMID:29347925 NCBI chr 6:42,400,238...42,401,119
Ensembl chr 6:42,400,238...42,401,119 		JBrowse link
G Timm17a translocase of inner mitochondrial membrane 17a multiple interactions
decreases expression		 ISO 1,10-phenanthroline inhibits the reaction [Adenosine Triphosphate results in decreased expression of TIMM17A protein] CTD PMID:24315374 NCBI chr 1:135,301,535...135,313,737
Ensembl chr 1:135,295,213...135,313,778 		JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 decreases secretion
multiple interactions		 EXP Adenosine Triphosphate results in decreased secretion of TIMP1 protein
azetidine analog inhibits the reaction [Adenosine Triphosphate results in decreased secretion of TIMP1 protein]		 CTD PMID:26522449 NCBI chr  X:20,870,166...20,874,737
Ensembl chr  X:20,870,166...20,874,735 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases chemical synthesis		 EXP
ISO		 [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of TNF protein; Adenosine Triphosphate deficiency inhibits the reaction [TNF protein results in increased transport of Chlorides]; Adenosine Triphosphate deficiency inhibits the reaction [TNF protein results in increased transport of Potassium]; Adenosine Triphosphate promotes the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased abundance of Dinoprostone]; azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased secretion of TNF protein]
TNF protein promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased chemical synthesis of Adenosine Triphosphate]
TNF protein results in decreased chemical synthesis of Adenosine Triphosphate
[Asbestos, Amosite co-treated with TNF protein] results in increased metabolism of Adenosine Triphosphate; Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; MFN2 protein inhibits the reaction [TNF protein results in decreased chemical synthesis of Adenosine Triphosphate]; Rosiglitazone inhibits the reaction [TNF protein results in decreased chemical synthesis of Adenosine Triphosphate]; Vitamin K 3 promotes the reaction [[Asbestos, Amosite co-treated with TNF protein] results in increased metabolism of Adenosine Triphosphate]		 CTD PMID:8817062 PMID:10783394 PMID:14623498 PMID:17707769 PMID:23430110 PMID:24898700 PMID:26522449 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007 		JBrowse link
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 increases abundance EXP TNFSF11 protein results in increased abundance of Adenosine Triphosphate CTD PMID:26287518 NCBI chr14:78,277,446...78,308,043
Ensembl chr14:78,277,445...78,308,043 		JBrowse link
G Top2a topoisomerase (DNA) II alpha multiple interactions
increases hydrolysis		 ISO Cannabidiol metabolite inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]; copper-thiosemicarbazone complex analog inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]; Dithiothreitol inhibits the reaction [Cannabidiol metabolite inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]]; Emodin inhibits the reaction [TOP2A results in increased hydrolysis of Adenosine Triphosphate]; Etoposide metabolite inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]; Thiosemicarbazones analog inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]
TOP2A protein results in increased hydrolysis of Adenosine Triphosphate; TOP2A results in increased hydrolysis of Adenosine Triphosphate		 CTD PMID:20855424 PMID:26982206 PMID:27533850 PMID:29272108 NCBI chr11:98,992,947...99,024,199
Ensembl chr11:98,992,943...99,024,189