Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:purine nucleobase
go back to main search page
Accession:CHEBI:26386 term browser browse the term
Definition:A nucleobase whose skeleton is derived from purine.
Synonyms:related_synonym: Formula=C5H3N4R2;   SMILES=C1(NC(=NC=2NC=NC12)*)=*;   a purine nucleobase;   purine bases;   purine nucleobases
 xref: KEGG:C15587


show annotations for term's descendants           Sort by:
3-isobutyl-1-methyl-7H-xanthine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFTR CF transmembrane conductance regulator multiple interactions EXP [1-Methyl-3-isobutylxanthine co-treated with 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP] results in increased activity of CFTR protein CTD PMID:15161604 NCBI chr14:56,290,417...56,452,919
Ensembl chr14:56,290,275...56,453,977 		JBrowse link
acyclovir term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AVP arginine vasopressin decreases activity EXP Acyclovir results in decreased activity of AVP protein CTD PMID:2724137 NCBI chr24:18,183,057...18,184,827
Ensembl chr24:18,183,057...18,184,883 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 499
    chemical entity 499
      atom 499
        nonmetal atom 492
          nitrogen atom 416
            nitrogen molecular entity 416
              organonitrogen compound 409
                organonitrogen heterocyclic compound 374
                  nucleobase 6
                    purine nucleobase 2
                      adenine + 0
                      guanine + 2
                      hypoxanthine + 0
                      purine 2'-deoxyribonucleoside 5'-phosphate(2-) + 0
                      purines D-ribonucleoside + 0
                      xanthine + 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 499
    subatomic particle 499
      composite particle 499
        hadron 499
          baryon 499
            nucleon 499
              atomic nucleus 499
                atom 499
                  main group element atom 492
                    p-block element atom 492
                      carbon group element atom 481
                        carbon atom 480
                          organic molecular entity 480
                            organic molecule 471
                              organic cyclic compound 454
                                organic heterocyclic compound 417
                                  organic heteropolycyclic compound 95
                                    organic heterobicyclic compound 44
                                      imidazopyrimidine 21
                                        purines 21
                                          purine nucleobase 2
                                            adenine + 0
                                            guanine + 2
                                            hypoxanthine + 0
                                            purine 2'-deoxyribonucleoside 5'-phosphate(2-) + 0
                                            purines D-ribonucleoside + 0
                                            xanthine + 1
paths to the root