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Accession:CHEBI:2637 term browser browse the term
Definition:An amino cyclitol glycoside that is kanamycin A acylated at the N-1 position by a 4-amino-2-hydroxybutyryl group.
Synonyms:exact_synonym: (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-(3-amino-3-deoxy-alpha-D-glucopyranosyloxy)-4-(6-amino-6-deoxy-alpha-D-glucopyranosyloxy)-3-hydroxycyclohexyl]-2-hydroxybutanamide
 related_synonym: 1-N-(L(-)-gamma-amino-alpha-hydroxybutyryl)kanamycin A;   Formula=C22H43N5O13;   InChI=1S/C22H43N5O13/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36)/t6-,7+,8-,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+/m0/s1;   InChIKey=LKCWBDHBTVXHDL-RMDFUYIESA-N;   O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1->4)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1->6))-N(3)-(4-amino-L-2-hydroxybutyryl)-2-deoxy-L-streptamine;   SMILES=NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](N)[C@H]1O;   amikacina;   amikacine;   amikacinum
 xref: Beilstein:5915117;   CAS:37517-28-5;   DrugBank:DB00479;   Drug_Central:157;   HMDB:HMDB0014622;   KEGG:C06820;   KEGG:D02543;   LINCS:LSM-5935
 xref_mesh: MESH:D000583
 xref: MetaCyc:CPD-14197;   PMID:11744283;   PMID:15305513;   PMID:17365906;   PMID:19495517;   PMID:19752274;   PMID:20195673;   PMID:25296102;   PMID:25327505;   PMID:25339395;   PMID:25630642;   PMID:8622103;   PMID:8622117;   PMID:9327246;   Patent:DE2234315;   Patent:US3781268;   Reaxys:5915117;   Wikipedia:Amikacin
 cyclic_relationship: is_conjugate_base_of CHEBI:84739

show annotations for term's descendants       view all columns           Sort by:
amikacin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc3 ATP binding cassette subfamily C member 3 JBrowse link 10 82,047,308 82,116,928 RGD:6480464
G Abcc4 ATP binding cassette subfamily C member 4 JBrowse link 15 103,695,415 103,927,980 RGD:6480464
G Casr calcium-sensing receptor JBrowse link 11 67,188,204 67,262,261 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Pgd phosphogluconate dehydrogenase JBrowse link 5 165,966,128 165,982,327 RGD:6480464
G Tyr tyrosinase JBrowse link 1 151,012,598 151,106,802 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19717
      biological role 19716
        antimicrobial agent 17260
          amikacin 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19655
                    p-block element atom 19655
                      carbon group element atom 19548
                        carbon atom 19537
                          organic molecular entity 19537
                            heteroorganic entity 19129
                              organochalcogen compound 18828
                                organooxygen compound 18747
                                  carbohydrates and carbohydrate derivatives 12146
                                    carbohydrate 12146
                                      monosaccharide 4019
                                        aldose 2534
                                          aldohexose 2180
                                            glucose 2141
                                              D-glucose 2141
                                                D-glucopyranose 1703
                                                  alpha-D-glucose 127
                                                    alpha-D-glucoside 126
                                                      amikacin 6
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.