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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:prostaglandins F
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Accession:CHEBI:26340 term browser browse the term
Synonyms:related_synonym: Formula=C5H8O2R2;   PGF;   SMILES=OC1C[C@@H](O)[C@H]([*])[C@H]1[*]
 xref_mesh: MESH:D011460


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6-oxoprostaglandin F1alpha term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EDN1 endothelin 1 multiple interactions EXP [15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid co-treated with EDN1 protein] results in decreased chemical synthesis of 6-Ketoprostaglandin F1 alpha CTD PMID:16325014 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348 		JBrowse link
prostaglandin F2alpha term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP3 caspase 3 increases activity
multiple interactions
increases expression		 EXP Dinoprost results in increased activity of CASP3 protein
[epostane co-treated with Dinoprost] results in increased activity of CASP3 protein; Dinoprost promotes the reaction [epostane results in increased expression of CASP3 mRNA]; epostane promotes the reaction [Dinoprost results in increased expression of CASP3 mRNA]		 CTD PMID:20739670 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213 		JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 increases expression
multiple interactions		 EXP Dinoprost results in increased expression of CCL2 mRNA
[Dinoprost co-treated with epostane] results in increased expression of CCL2 mRNA		 CTD PMID:21505051 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026 		JBrowse link
G CCL4 C-C motif chemokine ligand 4 increases expression
multiple interactions		 EXP Dinoprost results in increased expression of CCL4 mRNA
[Dinoprost co-treated with epostane] results in increased expression of CCL4 mRNA		 CTD PMID:21505051 NCBI chr12:39,479,190...39,480,511
Ensembl chr12:39,478,882...39,481,082 		JBrowse link
G CCL8 chemokine (C-C motif) ligand 8 increases expression
multiple interactions		 EXP Dinoprost results in increased expression of CCL8 mRNA
[Dinoprost co-treated with epostane] results in increased expression of CCL8 mRNA		 CTD PMID:21505051 NCBI chr12:40,740,468...40,741,970
Ensembl chr12:40,740,023...40,742,022 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 multiple interactions
increases expression		 EXP epostane promotes the reaction [Dinoprost results in increased expression of CCR1 mRNA] CTD PMID:21505051 NCBI chr13:29,227,218...29,233,862
Ensembl chr13:29,227,222...29,233,960 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 increases expression
multiple interactions		 EXP Dinoprost results in increased expression of CCR2 mRNA
epostane promotes the reaction [Dinoprost results in increased expression of CCR2 mRNA]		 CTD PMID:21505051 NCBI chr13:29,368,735...29,374,564
Ensembl chr13:29,285,012...29,376,343 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 increases expression
multiple interactions		 EXP Dinoprost results in increased expression of CCR5 mRNA
epostane promotes the reaction [Dinoprost results in increased expression of CCR5 mRNA]		 CTD PMID:21505051 NCBI chr13:29,382,383...29,387,902
Ensembl chr13:29,383,303...29,387,895 		JBrowse link
G CXCL2 chemokine (C-X-C motif) ligand 2 multiple interactions
increases expression		 EXP [Dinoprost co-treated with epostane] results in increased expression of CXCL2 mRNA
Dinoprost results in increased expression of CXCL2 mRNA		 CTD PMID:21505051 NCBI chr 8:70,157,253...70,159,145
Ensembl chr 8:70,157,214...70,159,138 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression
multiple interactions		 EXP Dinoprost results in increased expression of CXCL8 mRNA
[Dinoprost co-treated with epostane] results in increased expression of CXCL8 mRNA		 CTD PMID:21505051 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861 		JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 multiple interactions
increases expression		 EXP epostane promotes the reaction [Dinoprost results in increased expression of CXCR2 mRNA] CTD PMID:21505051 NCBI chr15:120,219,657...120,230,203 JBrowse link
G CYP19A3 cytochrome P450 19A3 multiple interactions EXP [epostane co-treated with Dinoprost] results in increased expression of CYP19A1 mRNA CTD PMID:20739670 NCBI chr 1:120,476,890...120,556,103
Ensembl chr 1:120,367,667...120,695,899 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide increases secretion
multiple interactions		 EXP GHRL protein results in increased secretion of Dinoprost
STAT1 protein inhibits the reaction [GHRL protein results in increased secretion of Dinoprost]		 CTD PMID:19528263 NCBI chr13:66,442,106...66,453,576
Ensembl chr13:66,445,992...66,452,917 		JBrowse link
G NFKBIA NFKB inhibitor alpha increases phosphorylation EXP Dinoprost results in increased phosphorylation of NFKBIA protein CTD PMID:21505051 NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,507,822...64,511,277 		JBrowse link
G OXT oxytocin/neurophysin I prepropeptide multiple interactions
increases abundance
increases secretion		 EXP Progesterone inhibits the reaction [OXT protein results in increased abundance of Dinoprost]; Progesterone inhibits the reaction [OXT protein results in increased secretion of Dinoprost] CTD PMID:16997130 PMID:21370738 NCBI chr17:32,605,586...32,606,449
Ensembl chr17:32,605,586...32,606,546 		JBrowse link
G PLA2G1B phospholipase A2 group IB multiple interactions EXP [epostane co-treated with Dinoprost] results in increased expression of PLA2G1B mRNA CTD PMID:20739670 NCBI chr14:40,314,520...40,322,315
Ensembl chr14:40,314,520...40,322,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [epostane co-treated with Dinoprost] results in increased expression of PTGS2 mRNA CTD PMID:20739670 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 multiple interactions
increases secretion		 EXP STAT1 protein inhibits the reaction [GHRL protein results in increased secretion of Dinoprost]
STAT1 protein results in increased secretion of Dinoprost		 CTD PMID:19528263 NCBI chr15:95,593,201...95,646,324
Ensembl chr15:95,593,211...95,646,260 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 5052
    chemical entity 5080
      atom 5043
        nonmetal atom 5006
          carbon atom 4954
            organic molecular entity 4926
              lipid 4408
                fatty acid derivative 91
                  icosanoid 27
                    prostanoid 27
                      prostaglandin 22
                        prostaglandins F 18
                          11-epi-prostaglandin F2alpha + 0
                          prostaglandins Falpha + 18
                          prostaglandins Fbeta + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 5052
    subatomic particle 5043
      composite particle 5043
        hadron 5071
          baryon 5043
            nucleon 5043
              atomic nucleus 5043
                atom 5043
                  main group element atom 5013
                    p-block element atom 5010
                      carbon group element atom 4927
                        carbon atom 4954
                          organic molecular entity 4926
                            heteroorganic entity 4768
                              organochalcogen compound 4730
                                organooxygen compound 4692
                                  carbon oxoacid 368
                                    carboxylic acid 364
                                      monocarboxylic acid 206
                                        fatty acid 131
                                          fatty acid derivative 91
                                            icosanoid 27
                                              prostanoid 27
                                                prostaglandin 22
                                                  prostaglandins F 18
                                                    11-epi-prostaglandin F2alpha + 0
                                                    prostaglandins Falpha + 18
                                                    prostaglandins Fbeta + 0
paths to the root