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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:prostaglandins F
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Accession:CHEBI:26340 term browser browse the term
Synonyms:related_synonym: Formula=C5H8O2R2;   PGF;   SMILES=OC1C[C@@H](O)[C@H]([*])[C@H]1[*]
 xref_mesh: MESH:D011460


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6-oxoprostaglandin F1alpha term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EDN1 endothelin 1 multiple interactions EXP [15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid co-treated with EDN1 protein] results in decreased chemical synthesis of 6-Ketoprostaglandin F1 alpha CTD PMID:16325014 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348
JBrowse link
prostaglandin F2alpha term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP3 caspase 3 increases activity
multiple interactions
increases expression
EXP Dinoprost results in increased activity of CASP3 protein
[epostane co-treated with Dinoprost] results in increased activity of CASP3 protein; Dinoprost promotes the reaction [epostane results in increased expression of CASP3 mRNA]; epostane promotes the reaction [Dinoprost results in increased expression of CASP3 mRNA]
CTD PMID:20739670 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,749...45,763,773
JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 increases expression
multiple interactions
EXP Dinoprost results in increased expression of CCL2 mRNA
[Dinoprost co-treated with epostane] results in increased expression of CCL2 mRNA
CTD PMID:21505051 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,028
JBrowse link
G CCL4 C-C motif chemokine ligand 4 increases expression
multiple interactions
EXP Dinoprost results in increased expression of CCL4 mRNA
[Dinoprost co-treated with epostane] results in increased expression of CCL4 mRNA
CTD PMID:21505051 NCBI chr12:39,479,190...39,480,511
Ensembl chr12:39,478,885...39,557,358
JBrowse link
G CCL8 chemokine (C-C motif) ligand 8 increases expression
multiple interactions
EXP Dinoprost results in increased expression of CCL8 mRNA
[Dinoprost co-treated with epostane] results in increased expression of CCL8 mRNA
CTD PMID:21505051 NCBI chr12:40,740,468...40,741,970
Ensembl chr12:40,740,023...40,742,022
JBrowse link
G CCR1 C-C motif chemokine receptor 1 multiple interactions
increases expression
EXP epostane promotes the reaction [Dinoprost results in increased expression of CCR1 mRNA] CTD PMID:21505051 NCBI chr13:29,227,218...29,233,862
Ensembl chr13:29,227,220...29,233,960
JBrowse link
G CCR2 C-C motif chemokine receptor 2 increases expression
multiple interactions
EXP Dinoprost results in increased expression of CCR2 mRNA
epostane promotes the reaction [Dinoprost results in increased expression of CCR2 mRNA]
CTD PMID:21505051 NCBI chr13:29,368,735...29,374,564
Ensembl chr13:29,251,959...29,376,346
JBrowse link
G CCR5 chemokine (C-C motif) receptor 5 increases expression
multiple interactions
EXP Dinoprost results in increased expression of CCR5 mRNA
epostane promotes the reaction [Dinoprost results in increased expression of CCR5 mRNA]
CTD PMID:21505051 NCBI chr13:29,382,383...29,387,902
Ensembl chr13:29,383,303...29,387,902
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression
multiple interactions
EXP Dinoprost results in increased expression of CXCL8 mRNA
[Dinoprost co-treated with epostane] results in increased expression of CXCL8 mRNA
CTD PMID:21505051 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861
JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 multiple interactions
increases expression
EXP epostane promotes the reaction [Dinoprost results in increased expression of CXCR2 mRNA] CTD PMID:21505051 NCBI chr15:120,219,657...120,230,203 JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 multiple interactions EXP [epostane co-treated with Dinoprost] results in increased expression of CYP19A1 mRNA CTD PMID:20739670 NCBI chr 1:120,596,235...120,627,806
Ensembl chr 1:120,367,667...120,695,899
JBrowse link
G GHRL ghrelin and obestatin prepropeptide increases secretion
multiple interactions
EXP GHRL protein results in increased secretion of Dinoprost
STAT1 protein inhibits the reaction [GHRL protein results in increased secretion of Dinoprost]
CTD PMID:19528263 NCBI chr13:66,442,106...66,453,576
Ensembl chr13:66,316,436...66,452,917
JBrowse link
G NFKBIA NFKB inhibitor alpha increases phosphorylation EXP Dinoprost results in increased phosphorylation of NFKBIA protein CTD PMID:21505051 NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,508,016...64,558,057
JBrowse link
G OXT oxytocin/neurophysin I prepropeptide multiple interactions
increases abundance
increases secretion
EXP Progesterone inhibits the reaction [OXT protein results in increased abundance of Dinoprost]; Progesterone inhibits the reaction [OXT protein results in increased secretion of Dinoprost] CTD PMID:16997130 PMID:21370738 NCBI chr17:32,605,586...32,606,449
Ensembl chr17:32,605,588...32,606,483
JBrowse link
G PLA2G1B phospholipase A2 group IB multiple interactions EXP [epostane co-treated with Dinoprost] results in increased expression of PLA2G1B mRNA CTD PMID:20739670 NCBI chr14:40,314,520...40,322,315
Ensembl chr14:40,314,444...40,322,319
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [epostane co-treated with Dinoprost] results in increased expression of PTGS2 mRNA CTD PMID:20739670 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,013...127,858,884
JBrowse link
G STAT1 signal transducer and activator of transcription 1 multiple interactions
increases secretion
EXP STAT1 protein inhibits the reaction [GHRL protein results in increased secretion of Dinoprost]
STAT1 protein results in increased secretion of Dinoprost
CTD PMID:19528263 NCBI chr15:95,593,201...95,646,324
Ensembl chr15:95,593,211...95,646,260
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 903
    chemical entity 903
      atom 888
        nonmetal atom 847
          carbon atom 829
            organic molecular entity 829
              fatty acid derivative 24
                icosanoid 21
                  prostanoid 21
                    prostaglandin 21
                      prostaglandins F 17
                        11-epi-prostaglandin F2alpha + 0
                        prostaglandins Falpha + 17
                        prostaglandins Fbeta + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 903
    subatomic particle 888
      composite particle 888
        hadron 888
          baryon 888
            nucleon 888
              atomic nucleus 888
                atom 888
                  main group element atom 857
                    p-block element atom 854
                      carbon group element atom 830
                        carbon atom 829
                          organic molecular entity 829
                            organic group 392
                              organic divalent group 390
                                organodiyl group 390
                                  carbonyl group 389
                                    carbonyl compound 389
                                      carboxylic acid 267
                                        monocarboxylic acid 135
                                          fatty acid 77
                                            fatty acid derivative 24
                                              icosanoid 21
                                                prostanoid 21
                                                  prostaglandin 21
                                                    prostaglandins F 17
                                                      11-epi-prostaglandin F2alpha + 0
                                                      prostaglandins Falpha + 17
                                                      prostaglandins Fbeta + 0
paths to the root