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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:prostaglandins A
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Accession:CHEBI:26334 term browser browse the term
Synonyms:related_synonym: Formula=C5H4OR2;   PGA;   SMILES=[*][C@@H]1[C@@H]([*])C=CC1=O


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prostaglandin A1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars1 alanyl-tRNA synthetase 1 increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of AARS protein CTD PMID:19800325 NCBI chr19:43,193,264...43,215,281
Ensembl chr19:43,193,257...43,215,281
JBrowse link
G Actn1 actinin, alpha 1 increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of ACTN1 protein CTD PMID:19800325 NCBI chr 6:103,376,557...103,470,497
Ensembl chr 6:103,375,799...103,470,555
JBrowse link
G Actn3 actinin alpha 3 increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of ACTN3 protein CTD PMID:19800325 NCBI chr 1:220,120,532...220,136,460
Ensembl chr 1:220,120,533...220,136,470
JBrowse link
G Actn4 actinin alpha 4 increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of ACTN4 protein CTD PMID:19800325 NCBI chr 1:87,078,012...87,147,347
Ensembl chr 1:87,078,020...87,147,333
JBrowse link
G Cryab crystallin, alpha B multiple interactions EXP prostaglandin A1 promotes the reaction [arsenite results in increased expression of CRYAB mRNA]; prostaglandin A1 promotes the reaction [arsenite results in increased expression of CRYAB protein] CTD PMID:9066782 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of EEF1A1 protein CTD PMID:19800325 NCBI chr 8:85,838,594...85,841,816
Ensembl chr 8:85,838,869...85,840,818
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of EEF2 protein CTD PMID:19800325 NCBI chr 7:11,401,501...11,406,771
Ensembl chr 7:11,401,501...11,406,771
JBrowse link
G Eno1 enolase 1 increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of ENO1 protein CTD PMID:19800325 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of GAPDH protein CTD PMID:19800325 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gpi glucose-6-phosphate isomerase increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of GPI1 protein CTD PMID:19800325 NCBI chr 1:90,063,411...90,091,287
Ensembl chr 1:90,063,411...90,091,287
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of HMGCS1 protein CTD PMID:19800325 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO prostaglandin A1 analog results in increased expression of HMOX1 protein; prostaglandin A1 results in increased expression of HMOX1 protein CTD PMID:19800325 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of HSP90AA1 protein CTD PMID:19800325 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of HSP90AB1 protein CTD PMID:19800325 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of HSP90B1 protein CTD PMID:19800325 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of HSPA4 protein CTD PMID:19800325 NCBI chr10:38,601,624...38,642,397
Ensembl chr10:38,601,624...38,642,397
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of HSPA8 protein CTD PMID:19800325 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of HSPH1 protein CTD PMID:19800325 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of IDH2 protein CTD PMID:19800325 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Ipo7 importin 7 increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of IPO7 protein CTD PMID:19800325 NCBI chr 1:174,655,939...174,696,173
Ensembl chr 1:174,655,939...174,696,173
JBrowse link
G Ldha lactate dehydrogenase A increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of LDHA protein CTD PMID:19800325 NCBI chr 1:102,900,288...102,909,713
Ensembl chr 1:102,900,286...102,909,707
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO prostaglandin A1 inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] CTD PMID:12031542 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Npepps aminopeptidase puromycin sensitive increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of NPEPPS protein CTD PMID:19800325 NCBI chr10:85,140,368...85,222,861
Ensembl chr10:85,140,370...85,222,861
JBrowse link
G Pgk1 phosphoglycerate kinase 1 increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of PGK1 protein CTD PMID:19800325 NCBI chr  X:77,263,399...77,279,373
Ensembl chr  X:77,263,359...77,279,367
JBrowse link
G Pgm1 phosphoglucomutase 1 increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of PGM1 protein CTD PMID:19800325 NCBI chr 5:118,743,632...118,803,055
Ensembl chr 5:118,743,632...118,803,055
JBrowse link
G Phgdh phosphoglycerate dehydrogenase increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of PHGDH protein CTD PMID:19800325 NCBI chr 2:200,484,245...200,513,564
Ensembl chr 2:200,484,246...200,513,564
JBrowse link
G Psat1 phosphoserine aminotransferase 1 increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of PSAT1 protein CTD PMID:19800325 NCBI chr 1:233,124,089...233,145,941
Ensembl chr 1:233,124,092...233,145,941
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO prostaglandin A1 inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:12031542 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rack1 receptor for activated C kinase 1 increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of RACK1 protein CTD PMID:19800325 NCBI chr10:34,149,717...34,155,198
Ensembl chr10:34,149,717...34,155,198
Ensembl chr12:34,149,717...34,155,198
JBrowse link
G Tubb5 tubulin, beta 5 class I increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of TUBB5 protein CTD PMID:19800325 NCBI chr20:3,422,448...3,426,420
Ensembl chr20:3,422,461...3,426,371
JBrowse link
G Uba1 ubiquitin-like modifier activating enzyme 1 increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of UBA1 protein CTD PMID:19800325 NCBI chr  X:1,723,135...1,745,147
Ensembl chr  X:1,723,174...1,741,701
JBrowse link
G Vcp valosin-containing protein increases metabolic processing ISO prostaglandin A1 analog results in increased metabolism of VCP protein CTD PMID:19800325 NCBI chr 5:58,426,548...58,445,953
Ensembl chr 5:58,426,549...58,445,953
JBrowse link
prostaglandin A2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cryab crystallin, alpha B multiple interactions EXP prostaglandin A2 promotes the reaction [arsenite results in increased expression of CRYAB mRNA]; prostaglandin A2 promotes the reaction [arsenite results in increased expression of CRYAB protein] CTD PMID:9066782 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 affects metabolic processing ISO GSTA1 protein affects the metabolism of prostaglandin A2 CTD PMID:9084911 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 affects metabolic processing ISO GSTA2 protein affects the metabolism of prostaglandin A2 CTD PMID:9084911 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects metabolic processing ISO GSTM1 protein affects the metabolism of prostaglandin A2 CTD PMID:9084911 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Tnf tumor necrosis factor increases abundance ISO TNF protein results in increased abundance of prostaglandin A2 CTD PMID:1993070 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    chemical entity 19785
      atom 19782
        nonmetal atom 19657
          carbon atom 19561
            organic molecular entity 19561
              olefinic compound 14455
                enone 8519
                  prostaglandins A 36
                    15-dehydroprostaglandin A1 0
                    15-deoxy-Delta(12,14)-prostaglandin A2 0
                    20-hydroxyprostaglandin A1 0
                    prostaglandin A1 + 32
                    prostaglandin A2 + 5
                    prostaglandin A3 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18493
                              organic divalent group 18486
                                organodiyl group 18486
                                  carbonyl group 18389
                                    carbonyl compound 18389
                                      carboxylic acid 18060
                                        monocarboxylic acid 17406
                                          fatty acid 15844
                                            fatty acid derivative 1021
                                              icosanoid 453
                                                prostanoid 395
                                                  prostaglandin 390
                                                    prostaglandins A 36
                                                      15-dehydroprostaglandin A1 0
                                                      15-deoxy-Delta(12,14)-prostaglandin A2 0
                                                      20-hydroxyprostaglandin A1 0
                                                      prostaglandin A1 + 32
                                                      prostaglandin A2 + 5
                                                      prostaglandin A3 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.