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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:ambenonium chloride
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Accession:CHEBI:2628 term browser browse the term
Definition:A symmetrical oxalamide-based bis-quaternary ammonium salt having ethyl and 2-chlorobenzyl groups attached to the nitrogens.
Synonyms:exact_synonym: 2,2'-[(1,2-dioxoethane-1,2-diyl)diimino]bis[N-(2-chlorobenzyl)-N,N-diethylethanaminium] dichloride
 related_synonym: (Oxalylbis(iminoethylene))bis((o-chlorobenzyl)diethylammonium) dichloride;   Ambenonium dichloride;   Ambestigmin chloride;   Chlorure d'ambenonium;   Cloruro de ambenonio;   Formula=C28H42Cl2N4O2.2Cl;   Formula=C28H42Cl4N4O2;   InChI=1S/C28H40Cl2N4O2.2ClH/c1-5-33(6-2,21-23-13-9-11-15-25(23)29)19-17-31-27(35)28(36)32-18-20-34(7-3,8-4)22-24-14-10-12-16-26(24)30;;/h9-16H,5-8,17-22H2,1-4H3;2*1H;   InChIKey=DXUUXWKFVDVHIK-UHFFFAOYSA-N;   N,N'-Bis(2-diethylaminoethyl)oxamide bis(2-chlorobenzyl chloride);   SMILES=[Cl-].[Cl-].CC[N+](CC)(CCNC(=O)C(=O)NCC[N+](CC)(CC)Cc1ccccc1Cl)Cc1ccccc1Cl;   ambenonii chloridum
 xref: Beilstein:7563564;   CAS:115-79-7;   DrugBank:DB01122;   KEGG:D01001
 xref_mesh: MESH:D000549
 xref: Patent:DE1024517


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ambenonium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO Ambenonium Chloride results in decreased activity of ACHE protein CTD PMID:33844597 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G App amyloid beta precursor protein affects cleavage EXP Ambenonium Chloride affects the cleavage of APP protein CTD PMID:11099780 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
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Path 1
Term Annotations click to browse term
  CHEBI ontology 19831
    role 19807
      biological role 19805
        pharmacological role 19054
          neurotransmitter agent 16734
            ambenonium chloride 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19831
    subatomic particle 19829
      composite particle 19829
        hadron 19829
          baryon 19829
            nucleon 19829
              atomic nucleus 19829
                atom 19829
                  main group element atom 19779
                    main group molecular entity 19779
                      s-block molecular entity 19617
                        hydrogen molecular entity 19604
                          hydrides 19102
                            inorganic hydride 18114
                              pnictogen hydride 18103
                                nitrogen hydride 18010
                                  ammonium 8311
                                    ammonium ion derivative 8306
                                      ammonium compound 5195
                                        organoammonium salt 655
                                          quaternary ammonium salt 537
                                            ambenonium chloride 2
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