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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:ambenonium chloride
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Accession:CHEBI:2628 term browser browse the term
Definition:A symmetrical oxalamide-based bis-quaternary ammonium salt having ethyl and 2-chlorobenzyl groups attached to the nitrogens.
Synonyms:exact_synonym: 2,2'-[(1,2-dioxoethane-1,2-diyl)diimino]bis[N-(2-chlorobenzyl)-N,N-diethylethanaminium] dichloride
 related_synonym: (Oxalylbis(iminoethylene))bis((o-chlorobenzyl)diethylammonium) dichloride;   Ambenonium dichloride;   Ambestigmin chloride;   Chlorure d'ambenonium;   Cloruro de ambenonio;   Formula=C28H42Cl2N4O2.2Cl;   Formula=C28H42Cl4N4O2;   InChI=1S/C28H40Cl2N4O2.2ClH/c1-5-33(6-2,21-23-13-9-11-15-25(23)29)19-17-31-27(35)28(36)32-18-20-34(7-3,8-4)22-24-14-10-12-16-26(24)30;;/h9-16H,5-8,17-22H2,1-4H3;2*1H;   InChIKey=DXUUXWKFVDVHIK-UHFFFAOYSA-N;   N,N'-Bis(2-diethylaminoethyl)oxamide bis(2-chlorobenzyl chloride);   SMILES=[Cl-].[Cl-].CC[N+](CC)(CCNC(=O)C(=O)NCC[N+](CC)(CC)Cc1ccccc1Cl)Cc1ccccc1Cl;   ambenonii chloridum
 xref: Beilstein:7563564;   CAS:115-79-7;   DrugBank:DB01122;   KEGG:D01001
 xref_mesh: MESH:D000549
 xref: Patent:DE1024517


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ambenonium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO Ambenonium Chloride results in decreased activity of ACHE protein CTD PMID:33844597 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G App amyloid beta precursor protein affects cleavage EXP Ambenonium Chloride affects the cleavage of APP protein CTD PMID:11099780 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
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Term Annotations click to browse term
  CHEBI ontology 20856
    role 20816
      biological role 20814
        pharmacological role 19906
          neurotransmitter agent 16942
            ambenonium chloride 2
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Term Annotations click to browse term
  CHEBI ontology 20856
    subatomic particle 20854
      composite particle 20854
        hadron 20854
          baryon 20854
            nucleon 20854
              atomic nucleus 20854
                atom 20854
                  main group element atom 20777
                    main group molecular entity 20777
                      s-block molecular entity 20573
                        hydrogen molecular entity 20557
                          hydrides 19691
                            inorganic hydride 18601
                              pnictogen hydride 18587
                                nitrogen hydride 18502
                                  ammonium 8464
                                    ammonium ion derivative 8459
                                      ammonium compound 5335
                                        organoammonium salt 673
                                          quaternary ammonium salt 555
                                            ambenonium chloride 2
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