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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ambenonium chloride
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Accession:CHEBI:2628 term browser browse the term
Definition:A symmetrical oxalamide-based bis-quaternary ammonium salt having ethyl and 2-chlorobenzyl groups attached to the nitrogens.
Synonyms:exact_synonym: 2,2'-[(1,2-dioxoethane-1,2-diyl)diimino]bis[N-(2-chlorobenzyl)-N,N-diethylethanaminium] dichloride
 related_synonym: (Oxalylbis(iminoethylene))bis((o-chlorobenzyl)diethylammonium) dichloride;   Ambenonium dichloride;   Ambestigmin chloride;   Chlorure d'ambenonium;   Cloruro de ambenonio;   Formula=C28H42Cl2N4O2.2Cl;   Formula=C28H42Cl4N4O2;   InChI=1S/C28H40Cl2N4O2.2ClH/c1-5-33(6-2,21-23-13-9-11-15-25(23)29)19-17-31-27(35)28(36)32-18-20-34(7-3,8-4)22-24-14-10-12-16-26(24)30;;/h9-16H,5-8,17-22H2,1-4H3;2*1H;   InChIKey=DXUUXWKFVDVHIK-UHFFFAOYSA-N;   N,N'-Bis(2-diethylaminoethyl)oxamide bis(2-chlorobenzyl chloride);   SMILES=[Cl-].[Cl-].CC[N+](CC)(CCNC(=O)C(=O)NCC[N+](CC)(CC)Cc1ccccc1Cl)Cc1ccccc1Cl;   ambenonii chloridum
 xref: Beilstein:7563564;   CAS:115-79-7;   DrugBank:DB01122;   KEGG:D01001
 xref_mesh: MESH:D000549
 xref: Patent:DE1024517

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ambenonium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO Ambenonium Chloride results in decreased activity of ACHE protein CTD PMID:33844597 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
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G App amyloid beta precursor protein affects cleavage EXP Ambenonium Chloride affects the cleavage of APP protein CTD PMID:11099780 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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  CHEBI ontology 19730
    role 19703
      biological role 19701
        pharmacological role 18949
          neurotransmitter agent 16594
            ambenonium chloride 2
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  CHEBI ontology 19730
    subatomic particle 19728
      composite particle 19728
        hadron 19728
          baryon 19728
            nucleon 19728
              atomic nucleus 19728
                atom 19728
                  main group element atom 19676
                    main group molecular entity 19676
                      s-block molecular entity 19531
                        hydrogen molecular entity 19523
                          hydrides 19007
                            inorganic hydride 17942
                              pnictogen hydride 17927
                                nitrogen hydride 17822
                                  ammonium 8298
                                    ammonium ion derivative 8294
                                      ammonium compound 5187
                                        organoammonium salt 642
                                          quaternary ammonium salt 530
                                            ambenonium chloride 2
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