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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:polyprenol
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Accession:CHEBI:26199 term browser browse the term
Definition:Any member of the class of prenols possessing the general formula H-[CH2C(Me)=CHCH2]nOH in which the carbon skeleton is composed of more than one isoprene units.
Synonyms:related_synonym: Formula=(C5H8)nC10H18O;   polyprenols
 alt_id: CHEBI:8317
 xref: KEGG:C06081


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2-trans,6-trans,10-trans-geranylgeranyl diphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A multiple interactions EXP geranylgeranyl pyrophosphate inhibits the reaction [kuwanon G results in increased expression of ABCB1 protein] CTD PMID:29355567 NCBI chr 5:8,567,091...8,748,575
Ensembl chr 5:8,660,077...8,748,575
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 multiple interactions EXP geranylgeranyl pyrophosphate inhibits the reaction [kuwanon G results in increased expression of ABCG1 protein] CTD PMID:29355567 NCBI chr17:31,057,694...31,117,984
Ensembl chr17:31,057,675...31,117,988
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of AKT1 mRNA] CTD PMID:18031796 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of BCL2 mRNA] CTD PMID:18031796 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in decreased expression of BIRC5 protein] CTD PMID:17472962 NCBI chr11:117,849,237...117,855,743
Ensembl chr11:117,849,251...117,855,743
JBrowse link
G Bmp2 bone morphogenetic protein 2 multiple interactions EXP geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]] CTD PMID:18310456 NCBI chr 2:133,552,159...133,562,896
Ensembl chr 2:133,552,159...133,562,885
JBrowse link
G Casp3 caspase 3 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin results in increased activity of CASP3 protein]; geranylgeranyl pyrophosphate inhibits the reaction [cerivastatin results in increased activity of CASP3 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased activity of and results in increased cleavage of CASP3 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in increased activity of CASP3 protein] CTD PMID:15200425 PMID:16470222 PMID:18766339 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TGFB1 results in increased expression of CCN2 mRNA]] CTD PMID:15298857 NCBI chr10:24,595,442...24,598,683
Ensembl chr10:24,595,442...24,598,683
JBrowse link
G Ccna2 cyclin A2 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CCNA2 protein] CTD PMID:26577051 NCBI chr 3:36,564,865...36,573,038
Ensembl chr 3:36,564,865...36,572,150
JBrowse link
G Ccne1 cyclin E1 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CCNE1 protein] CTD PMID:26577051 NCBI chr 7:38,097,984...38,107,490
Ensembl chr 7:38,097,984...38,107,534
JBrowse link
G Cd40 CD40 antigen multiple interactions EXP geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CD40 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CD40 protein]] CTD PMID:17507688 NCBI chr 2:165,055,614...165,071,654
Ensembl chr 2:165,055,627...165,072,948
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CDK1 protein] CTD PMID:26577051 NCBI chr10:69,335,146...69,352,912
Ensembl chr10:69,335,146...69,352,938
JBrowse link
G Cdk2 cyclin-dependent kinase 2 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CDK2 protein] CTD PMID:26577051 NCBI chr10:128,697,938...128,705,051
Ensembl chr10:128,697,939...128,705,031
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in increased expression of CDKN1A protein] CTD PMID:18625202 NCBI chr17:29,090,979...29,100,722
Ensembl chr17:29,090,976...29,100,727
JBrowse link
G Col1a1 collagen, type I, alpha 1 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of COL1A1 mRNA] CTD PMID:16575855 NCBI chr11:94,936,224...94,953,042
Ensembl chr11:94,936,224...94,953,042
JBrowse link
G Crp C-reactive protein, pentraxin-related multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [CRP results in increased expression of RETN mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [CRP results in increased secretion of RETN protein]] CTD PMID:18023360 NCBI chr 1:172,698,056...172,699,966
Ensembl chr 1:172,698,055...172,833,031
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]] CTD PMID:16511915 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CYP17A1 mRNA] CTD PMID:21918126 NCBI chr19:46,667,165...46,673,000
Ensembl chr19:46,667,165...46,673,172
JBrowse link
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 multiple interactions EXP geranylgeranyl pyrophosphate inhibits the reaction [resveratrol results in increased expression of CYP7A1 mRNA] CTD PMID:22607622 NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633
JBrowse link
G F3 coagulation factor III multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of F3 mRNA] CTD PMID:18031796 NCBI chr 3:121,723,537...121,735,052
Ensembl chr 3:121,723,537...121,735,048
JBrowse link
G Fbxo32 F-box protein 32 multiple interactions EXP geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased expression of FBXO32 mRNA]; geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased expression of FBXO32 protein] CTD PMID:19406843 NCBI chr15:58,175,879...58,214,892
Ensembl chr15:58,175,879...58,214,932
JBrowse link
G Ggps1 geranylgeranyl diphosphate synthase 1 decreases activity ISO geranylgeranyl pyrophosphate analog results in decreased activity of GGPS1 protein CTD PMID:16787319 NCBI chr13:14,049,790...14,063,566
Ensembl chr13:14,050,659...14,063,488
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase multiple interactions ISO [Lovastatin results in decreased activity of HMGCR protein] which results in decreased abundance of geranylgeranyl pyrophosphate CTD PMID:17208200 NCBI chr13:96,648,962...96,670,936
Ensembl chr13:96,648,967...96,670,936
JBrowse link
G Hras Harvey rat sarcoma virus oncogene multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased activity of HRAS protein]] CTD PMID:18625914 NCBI chr 7:141,189,934...141,194,019
Ensembl chr 7:141,189,105...141,194,005
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of ICAM1 protein]] CTD PMID:10946302 NCBI chr 9:21,015,940...21,028,814
Ensembl chr 9:21,015,985...21,028,817
JBrowse link
G Ifng interferon gamma multiple interactions EXP geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CD40 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CD40 protein]] CTD PMID:17507688 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Il12b interleukin 12b multiple interactions EXP geranylgeranyl pyrophosphate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B protein] CTD PMID:15187114 NCBI chr11:44,400,063...44,414,677
Ensembl chr11:44,400,063...44,414,033
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased expression of MMP9 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]]
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in decreased expression of NOS2 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in increased abundance of Nitric Oxide]]
CTD PMID:15705589 PMID:15728660 NCBI chr 2:129,299,609...129,310,186
Ensembl chr 2:129,299,610...129,309,972
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased secretion of IL1B protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of ICAM1 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]] CTD PMID:10946302 PMID:17075836 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of IL6 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased secretion of IL6 protein]]
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [[Lipopolysaccharides co-treated with TNF] results in increased expression of IL6 protein]]
CTD PMID:16511915 PMID:17075836 PMID:17729120 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Lep leptin multiple interactions EXP geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of LEP mRNA]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased secretion of LEP protein] CTD PMID:19254925 NCBI chr 6:29,060,221...29,073,876
Ensembl chr 6:29,060,220...29,073,877
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin results in decreased phosphorylation of MAPK1 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]] CTD PMID:16470222 PMID:18625914 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin results in decreased phosphorylation of MAPK3 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]] CTD PMID:16470222 PMID:18625914 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mbp myelin basic protein multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased expression of MBP mRNA] CTD PMID:20578043 NCBI chr18:82,475,091...82,585,637
Ensembl chr18:82,475,146...82,585,637
JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of MMP1]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of MMP1 mRNA]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of MMP1 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased secretion of MMP1 protein] CTD PMID:17303772 PMID:18625914 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased expression of MMP9 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]]
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Smoke analog results in increased expression of MMP9 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Smoke analog results in increased expression of MMP9]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Smoke analog results in increased secretion of MMP9 protein]]
CTD PMID:15728660 PMID:19299917 NCBI chr 2:164,940,326...164,955,850
Ensembl chr 2:164,940,780...164,955,850
JBrowse link
G Mvk mevalonate kinase decreases activity
decreases chemical synthesis
multiple interactions
ISO geranylgeranyl pyrophosphate results in decreased activity of MVK protein
MVK protein mutant form results in decreased chemical synthesis of geranylgeranyl pyrophosphate
geranylgeranyl pyrophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; geranylgeranyl pyrophosphate inhibits the reaction [MVK protein results in increased phosphorylation of Mevalonic Acid]
CTD PMID:9392419 PMID:24073415 NCBI chr 5:114,444,264...114,460,591
Ensembl chr 5:114,444,269...114,460,591
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased degradation of NFKBIA protein]] CTD PMID:17075836 NCBI chr12:55,489,409...55,492,647
Ensembl chr12:55,489,410...55,492,647
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in decreased expression of NOS2 protein]] CTD PMID:15705589 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 decreases activity EXP geranylgeranyl pyrophosphate results in decreased activity of NR1H3 protein CTD PMID:22607622 NCBI chr 2:91,184,061...91,202,829
Ensembl chr 2:91,184,061...91,202,834
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of NR4A3 mRNA] CTD PMID:16005304 NCBI chr 4:48,045,078...48,086,447
Ensembl chr 4:48,045,153...48,086,447
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [TNFSF10 protein promotes the reaction [Simvastatin results in increased cleavage of PARP1 protein]] CTD PMID:21910007 NCBI chr 1:180,568,891...180,600,999
Ensembl chr 1:180,568,924...180,601,254
JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased expression of MMP9 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]] CTD PMID:15728660 NCBI chr15:79,995,865...80,024,614
Ensembl chr15:79,995,874...80,014,977
JBrowse link
G Plat plasminogen activator, tissue multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased expression of PLAT protein] CTD PMID:10412747 NCBI chr 8:22,757,722...22,782,848
Ensembl chr 8:22,757,727...22,782,844
JBrowse link
G Pon1 paraoxonase 1 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in increased expression of PON1 mRNA] CTD PMID:14500290 NCBI chr 6:5,168,090...5,193,987
Ensembl chr 6:5,168,090...5,193,946
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased expression of PPARG mRNA] CTD PMID:20578043 NCBI chr 6:115,360,879...115,490,404
Ensembl chr 6:115,360,951...115,490,399
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased expression of PTEN mRNA] CTD PMID:20578043 NCBI chr19:32,757,577...32,826,160
Ensembl chr19:32,757,497...32,826,160
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin inhibits the reaction [Glucose results in increased localization of RAC1 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased activity of RAC1 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased localization of RAC1 protein]] CTD PMID:17279352 PMID:18625914 NCBI chr 5:143,505,481...143,528,031
Ensembl chr 5:143,503,634...143,528,036
JBrowse link
G Retn resistin multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [CRP results in increased expression of RETN mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [CRP results in increased secretion of RETN protein]] CTD PMID:18023360 NCBI chr 8:3,655,770...3,659,818
Ensembl chr 8:3,655,770...3,660,110
JBrowse link
G Rhoa ras homolog family member A multiple interactions ISO
EXP
geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin results in decreased activity of RHOA protein]; geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin results in increased localization of RHOA protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin affects the localization of and results in decreased activity of RHOA protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in decreased activity of RHOA protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased activity of RHOA protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased activity of RHOA protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in increased localization of RHOA protein]; Simvastatin inhibits the reaction [geranylgeranyl pyrophosphate affects the localization of RHOA protein]
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF affects the localization of RHOA protein]]
CTD PMID:16005304 PMID:16470222 PMID:17075836 PMID:18031796 PMID:18310456 PMID:18625202 PMID:18625914 NCBI chr 9:108,306,160...108,337,943
Ensembl chr 9:108,306,129...108,337,934
JBrowse link
G Runx2 runt related transcription factor 2 multiple interactions EXP geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]] CTD PMID:18310456 NCBI chr17:44,495,987...44,814,797
Ensembl chr17:44,495,987...44,814,797
JBrowse link
G Sele selectin, endothelial cell multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]] CTD PMID:10946302 NCBI chr 1:164,039,614...164,058,487
Ensembl chr 1:164,048,234...164,057,677
JBrowse link
G Sox10 SRY (sex determining region Y)-box 10 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased expression of SOX10 mRNA] CTD PMID:20578043 NCBI chr15:79,154,913...79,164,490
Ensembl chr15:79,154,908...79,165,240
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions
increases expression
EXP geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of STAT1 mRNA]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of STAT1 protein]
geranylgeranyl pyrophosphate results in increased expression of STAT1 protein
CTD PMID:17507688 NCBI chr 1:52,119,438...52,161,865
Ensembl chr 1:52,119,440...52,161,865
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TGFB1 results in increased expression of CCN2 mRNA]] CTD PMID:15298857 NCBI chr 7:25,687,002...25,705,077
Ensembl chr 7:25,687,002...25,705,077
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased activity of RHOA protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased degradation of NFKBIA protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of IL6 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased secretion of IL1B protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased secretion of IL6 protein]]
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF affects the localization of RHOA protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [[Lipopolysaccharides co-treated with TNF] results in increased abundance of Nitric Oxide]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [[Lipopolysaccharides co-treated with TNF] results in increased expression of IL6 protein]]
CTD PMID:16511915 PMID:17075836 PMID:17729120 PMID:18310456 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [TNFSF10 protein promotes the reaction [Simvastatin results in increased cleavage of PARP1 protein]] CTD PMID:21910007 NCBI chr 3:27,317,077...27,339,665
Ensembl chr 3:27,317,028...27,342,427
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in increased expression of VEGFA mRNA] CTD PMID:18356691 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link
2-trans,6-trans-farnesyl diphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Lovastatin results in decreased expression of BIRC5 protein] CTD PMID:17472962 NCBI chr11:117,849,237...117,855,743
Ensembl chr11:117,849,251...117,855,743
JBrowse link
G Bmp2 bone morphogenetic protein 2 multiple interactions EXP farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]] CTD PMID:18310456 NCBI chr 2:133,552,159...133,562,896
Ensembl chr 2:133,552,159...133,562,885
JBrowse link
G Casp3 caspase 3 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Lovastatin results in increased activity of and results in increased cleavage of CASP3 protein]
farnesyl pyrophosphate inhibits the reaction [Simvastatin results in increased activity of CASP3 protein]
CTD PMID:15200425 PMID:18766339 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CYP17A1 mRNA] CTD PMID:21918126 NCBI chr19:46,667,165...46,673,000
Ensembl chr19:46,667,165...46,673,172
JBrowse link
G Fnta farnesyltransferase, CAAX box, alpha multiple interactions ISO [FNTA protein binds to FNTB protein] binds to [farnesyl pyrophosphate analog co-treated with KRAS protein] CTD PMID:10673434 NCBI chr 8:25,998,688...26,015,610
Ensembl chr 8:25,998,722...26,015,650
JBrowse link
G Fntb farnesyltransferase, CAAX box, beta multiple interactions ISO [FNTA protein binds to FNTB protein] binds to [farnesyl pyrophosphate analog co-treated with KRAS protein] CTD PMID:10673434 NCBI chr12:76,837,400...76,921,412
Ensembl chr12:76,765,589...76,921,412
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of FOS mRNA] CTD PMID:16005304 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase multiple interactions ISO [Lovastatin results in decreased activity of HMGCR protein] which results in decreased abundance of farnesyl pyrophosphate CTD PMID:17208200 NCBI chr13:96,648,962...96,670,936
Ensembl chr13:96,648,967...96,670,936
JBrowse link
G Hras Harvey rat sarcoma virus oncogene multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased activity of HRAS protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased localization of HRAS protein]] CTD PMID:18625914 NCBI chr 7:141,189,934...141,194,019
Ensembl chr 7:141,189,105...141,194,005
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of ICAM1 protein]] CTD PMID:10946302 NCBI chr 9:21,015,940...21,028,814
Ensembl chr 9:21,015,985...21,028,817
JBrowse link
G Il12b interleukin 12b multiple interactions EXP farnesyl pyrophosphate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B protein] CTD PMID:15187114 NCBI chr11:44,400,063...44,414,677
Ensembl chr11:44,400,063...44,414,033
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of ICAM1 protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]] CTD PMID:10946302 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog multiple interactions ISO [FNTA protein binds to FNTB protein] binds to [farnesyl pyrophosphate analog co-treated with KRAS protein] CTD PMID:10673434 NCBI chr 6:145,216,699...145,250,420
Ensembl chr 6:145,216,699...145,250,239
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions EXP farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK1 protein]] CTD PMID:18310456 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions EXP farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK3 protein]] CTD PMID:18310456 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein]] CTD PMID:18310456 NCBI chr14:33,377,898...33,447,353
Ensembl chr14:33,377,898...33,447,158
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Smoke analog results in increased expression of MMP9 mRNA]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Smoke analog results in increased secretion of MMP9 protein]] CTD PMID:19299917 NCBI chr 2:164,940,326...164,955,850
Ensembl chr 2:164,940,780...164,955,850
JBrowse link
G Mvk mevalonate kinase decreases activity
decreases chemical synthesis
multiple interactions
ISO farnesyl pyrophosphate results in decreased activity of MVK protein
MVK protein mutant form results in decreased chemical synthesis of farnesyl pyrophosphate
farnesyl pyrophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; farnesyl pyrophosphate inhibits the reaction [MVK protein results in increased phosphorylation of Mevalonic Acid]
CTD PMID:9392419 PMID:24073415 NCBI chr 5:114,444,264...114,460,591
Ensembl chr 5:114,444,269...114,460,591
JBrowse link
G Pon1 paraoxonase 1 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [pitavastatin results in increased expression of PON1 mRNA]; farnesyl pyrophosphate inhibits the reaction [Simvastatin results in increased expression of PON1 mRNA] CTD PMID:14500290 PMID:15690306 NCBI chr 6:5,168,090...5,193,987
Ensembl chr 6:5,168,090...5,193,946
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased activity of RAC1 protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased localization of RAC1 protein]] CTD PMID:18625914 NCBI chr 5:143,505,481...143,528,031
Ensembl chr 5:143,503,634...143,528,036
JBrowse link
G Rhoa ras homolog family member A multiple interactions ISO
EXP
farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in decreased activity of RHOA protein]]
farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF affects the localization of RHOA protein]]
CTD PMID:18310456 PMID:18625914 NCBI chr 9:108,306,160...108,337,943
Ensembl chr 9:108,306,129...108,337,934
JBrowse link
G Runx2 runt related transcription factor 2 multiple interactions EXP farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]] CTD PMID:18310456 NCBI chr17:44,495,987...44,814,797
Ensembl chr17:44,495,987...44,814,797
JBrowse link
G Sele selectin, endothelial cell multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]] CTD PMID:10946302 NCBI chr 1:164,039,614...164,058,487
Ensembl chr 1:164,048,234...164,057,677
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF affects the localization of RHOA protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK1 protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK3 protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein]] CTD PMID:18310456 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
dolichyl phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mvk mevalonate kinase decreases activity
multiple interactions
ISO dolichol monophosphate results in decreased activity of MVK protein
dolichol monophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; dolichol monophosphate inhibits the reaction [MVK protein results in increased phosphorylation of Mevalonic Acid]
CTD PMID:9392419 NCBI chr 5:114,444,264...114,460,591
Ensembl chr 5:114,444,269...114,460,591
JBrowse link
farnesol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa1b acetyl-Coenzyme A acyltransferase 1B multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACAA1 mRNA CTD PMID:30611723 NCBI chr 9:119,148,043...119,157,093
Ensembl chr 9:119,148,023...119,157,093
JBrowse link
G Acaa2 acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) multiple interactions
increases expression
ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACAA2 mRNA
Farnesol analog results in increased expression of ACAA2 mRNA
CTD PMID:30611723 NCBI chr18:74,779,212...74,806,207
Ensembl chr18:74,779,197...74,806,208
JBrowse link
G Acadm acyl-Coenzyme A dehydrogenase, medium chain multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACADM mRNA CTD PMID:30611723 NCBI chr 3:153,922,353...153,944,643
Ensembl chr 3:153,922,357...153,944,632
JBrowse link
G Acads acyl-Coenzyme A dehydrogenase, short chain multiple interactions
increases expression
ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACADS mRNA
Farnesol analog results in increased expression of ACADS mRNA
CTD PMID:30611723 NCBI chr 5:115,110,299...115,119,346
Ensembl chr 5:115,110,299...115,119,346
JBrowse link
G Acat1 acetyl-Coenzyme A acetyltransferase 1 increases expression ISO Farnesol analog results in increased expression of ACAT1 mRNA CTD PMID:30611723 NCBI chr 9:53,580,522...53,610,350
Ensembl chr 9:53,580,522...53,610,382
JBrowse link
G Acat2 acetyl-Coenzyme A acetyltransferase 2 increases expression ISO Farnesol analog results in increased expression of ACAT2 mRNA CTD PMID:30611723 NCBI chr17:12,943,042...12,960,725
Ensembl chr17:12,942,890...12,960,747
JBrowse link
G Acot1 acyl-CoA thioesterase 1 multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACOT1 mRNA CTD PMID:30611723 NCBI chr12:84,009,502...84,017,670
Ensembl chr12:84,009,490...84,018,371
JBrowse link
G Acot12 acyl-CoA thioesterase 12 multiple interactions
increases expression
ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACOT12 mRNA
Farnesol analog results in increased expression of ACOT12 mRNA
CTD PMID:30611723 NCBI chr13:91,741,326...91,786,148
Ensembl chr13:91,741,512...91,786,148
JBrowse link
G Acot6 acyl-CoA thioesterase 6 multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in decreased expression of ACOT6 mRNA CTD PMID:30611723 NCBI chr12:84,100,654...84,109,783
Ensembl chr12:84,100,654...84,111,349
JBrowse link
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA CTD PMID:30611723 NCBI chr11:116,171,883...116,199,045
Ensembl chr11:116,171,888...116,199,045
JBrowse link
G Acox2 acyl-Coenzyme A oxidase 2, branched chain increases expression
decreases expression
ISO Farnesol analog results in increased expression of ACOX2 mRNA
Farnesol analog results in decreased expression of ACOX2 mRNA
CTD PMID:30611723 NCBI chr14:8,225,511...8,259,019
Ensembl chr14:8,225,511...8,259,353
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACSL4 mRNA CTD PMID:30611723 NCBI chr  X:142,317,993...142,390,802
Ensembl chr  X:142,317,993...142,390,535
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACSL5 mRNA CTD PMID:30611723 NCBI chr19:55,251,861...55,296,628
Ensembl chr19:55,251,938...55,297,720
JBrowse link
G Agpat1 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in decreased expression of AGPAT1 mRNA CTD PMID:30611723 NCBI chr17:34,604,195...34,613,449
Ensembl chr17:34,604,262...34,613,449
JBrowse link
G Akr1b10 aldo-keto reductase family 1, member B10 (aldose reductase) increases chemical synthesis ISO AKR1B10 protein results in increased chemical synthesis of Farnesol CTD PMID:21187079 NCBI chr 6:34,384,247...34,396,949
Ensembl chr 6:34,384,218...34,396,950
JBrowse link
G Akr1c18 aldo-keto reductase family 1, member C18 increases chemical synthesis
multiple interactions
ISO AKR1C3 protein results in increased chemical synthesis of Farnesol
[Flurbiprofen results in decreased activity of AKR1C3 protein] which results in increased metabolism of Farnesol; [tolfenamic acid results in decreased activity of AKR1C3 protein] which results in increased metabolism of Farnesol
CTD PMID:21187079 NCBI chr13:4,132,615...4,150,646
Ensembl chr13:4,132,615...4,150,654
JBrowse link
G Akr1c20 aldo-keto reductase family 1, member C20 increases expression ISO Farnesol results in increased expression of AKR1C1 mRNA CTD PMID:30806763 NCBI chr13:4,486,856...4,523,354
Ensembl chr13:4,486,849...4,523,345
JBrowse link
G Apoa5 apolipoprotein A-V increases expression
multiple interactions
ISO Farnesol analog results in increased expression of APOA5 mRNA
[Farnesol analog co-treated with Oleic Acid] results in increased expression of APOA5 mRNA
CTD PMID:30611723 NCBI chr 9:46,268,608...46,271,921
Ensembl chr 9:46,268,633...46,271,919
JBrowse link
G Apoc4 apolipoprotein C-IV decreases expression ISO Farnesol analog results in decreased expression of APOC4 mRNA CTD PMID:30611723 NCBI chr 7:19,678,084...19,681,460
Ensembl chr 7:19,678,083...19,681,479
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Farnesol results in increased expression of ATF3 mRNA CTD PMID:27965148 NCBI chr 1:191,170,296...191,183,333
Ensembl chr 1:191,170,296...191,218,039
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO Farnesol results in increased expression of BAK1 protein CTD PMID:12530055 NCBI chr17:27,019,812...27,028,627
Ensembl chr17:27,019,810...27,029,009
JBrowse link
G Casp3 caspase 3 increases activity
decreases activity
ISO Farnesol results in increased activity of CASP3 protein
Farnesol results in decreased activity of CASP3 protein
CTD PMID:10733934 PMID:21453689 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Cat catalase increases expression
multiple interactions
ISO Farnesol results in increased expression of CAT protein
Farnesol inhibits the reaction [Tobacco Smoke Pollution results in decreased activity of CAT protein]
CTD PMID:18793622 PMID:21453689 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Ccl4 chemokine (C-C motif) ligand 4 increases secretion ISO Farnesol results in increased secretion of CCL4 protein CTD PMID:30806763 NCBI chr11:83,648,624...83,664,683
Ensembl chr11:83,662,584...83,664,683
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Farnesol results in decreased expression of CCNA2 protein CTD PMID:17138864 NCBI chr 3:36,564,865...36,573,038
Ensembl chr 3:36,564,865...36,572,150
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Farnesol results in decreased expression of CCNB1 protein CTD PMID:17138864 NCBI chr13:100,778,739...100,786,486
Ensembl chr13:100,778,650...100,786,570
JBrowse link
G Cdk2 cyclin-dependent kinase 2 decreases expression
multiple interactions
ISO Farnesol results in decreased expression of CDK2 protein
Farnesol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein]; Farnesol promotes the reaction [CDKN1B protein binds to and results in decreased activity of CDK2 protein]
CTD PMID:17138864 NCBI chr10:128,697,938...128,705,051
Ensembl chr10:128,697,939...128,705,031
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) increases response to substance
increases expression
multiple interactions
ISO CDKN1A protein results in increased susceptibility to Farnesol
Farnesol results in increased expression of CDKN1A protein
Farnesol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein]
CTD PMID:17138864 NCBI chr17:29,090,979...29,100,722
Ensembl chr17:29,090,976...29,100,727
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression
increases response to substance
multiple interactions
ISO Farnesol results in increased expression of CDKN1B protein
CDKN1B protein results in increased susceptibility to Farnesol
Farnesol promotes the reaction [CDKN1B protein binds to and results in decreased activity of CDK2 protein]
CTD PMID:17138864 NCBI chr 6:134,920,401...134,925,525
Ensembl chr 6:134,920,401...134,925,513
JBrowse link
G Cox10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 10 decreases expression ISO Farnesol analog results in decreased expression of COX10 mRNA CTD PMID:30611723 NCBI chr11:63,962,627...64,079,472
Ensembl chr11:63,962,627...64,079,468
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of CPT1A mRNA CTD PMID:30611723 NCBI chr19:3,322,326...3,385,735
Ensembl chr19:3,322,334...3,385,733
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 increases expression
increases secretion
ISO Farnesol results in increased expression of CXCL8 mRNA
Farnesol results in increased secretion of CXCL8 protein
CTD PMID:27965148 PMID:30806763 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity ISO Farnesol results in increased activity of CYP19A1 protein CTD PMID:15840382 NCBI chr 9:54,165,937...54,268,164
Ensembl chr 9:54,165,937...54,268,110
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
increases expression
ISO Farnesol results in increased activity of CYP1A1 protein
Farnesol results in increased expression of CYP1A1 mRNA
CTD PMID:15840382 PMID:30806763 NCBI chr 9:57,687,928...57,703,824
Ensembl chr 9:57,687,928...57,703,824
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases activity
multiple interactions
ISO Farnesol results in increased activity of CYP1A2 protein
Farnesol analog inhibits the reaction [Oleic Acid results in decreased expression of CYP1A2 mRNA]
CTD PMID:15840382 PMID:30611723 NCBI chr 9:57,676,937...57,683,655
Ensembl chr 9:57,676,937...57,683,703
JBrowse link
G Cyp2a22 cytochrome P450, family 2, subfamily a, polypeptide 22 increases activity ISO Farnesol results in increased activity of CYP2A1 protein CTD PMID:15840382 NCBI chr 7:26,931,631...26,939,413
Ensembl chr 7:26,931,631...26,939,384
JBrowse link
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 increases activity ISO Farnesol results in increased activity of CYP2A3 protein CTD PMID:15840382 NCBI chr 7:26,835,339...26,843,264
Ensembl chr 7:26,835,305...26,843,548
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 increases activity
increases expression
multiple interactions
ISO Farnesol results in increased activity of CYP2B1 protein
Farnesol analog results in increased expression of CYP2B6 mRNA; Farnesol results in increased expression of CYP2B6 mRNA
[Farnesol analog co-treated with Oleic Acid] results in increased expression of CYP2B6 mRNA; Farnesol analog inhibits the reaction [Oleic Acid results in decreased expression of CYP2B6 mRNA]
CTD PMID:15840382 PMID:30611723 NCBI chr 7:25,897,658...25,926,624
Ensembl chr 7:25,897,620...25,926,624
JBrowse link
G Cyp2b13 cytochrome P450, family 2, subfamily b, polypeptide 13 increases activity ISO Farnesol results in increased activity of CYP2B2 protein CTD PMID:15840382 NCBI chr 7:26,061,388...26,096,197
Ensembl chr 7:26,061,497...26,096,197
JBrowse link
G Cyp2c52-ps cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene increases activity ISO Farnesol results in increased activity of CYP2C11 protein CTD PMID:15840382 NCBI chr19:38,976,662...39,003,627
Ensembl chr19:38,976,647...39,003,289
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases activity
decreases expression
multiple interactions
ISO Farnesol results in increased activity of CYP2E1 protein
Farnesol analog results in decreased expression of CYP2E1 mRNA; Farnesol results in decreased expression of CYP2E1 mRNA
[Farnesol analog co-treated with Oleic Acid] results in increased expression of CYP2E1 mRNA; Farnesol analog inhibits the reaction [Oleic Acid results in increased expression of CYP2E1 mRNA]
CTD PMID:15840382 PMID:30611723 NCBI chr 7:140,763,819...140,774,990
Ensembl chr 7:140,763,739...140,774,987
JBrowse link
G Cyp4a12b cytochrome P450, family 4, subfamily a, polypeptide 12B increases activity ISO Farnesol results in increased activity of CYP4A1 protein CTD PMID:15840382 NCBI chr 4:115,411,624...115,439,034
Ensembl chr 4:115,411,624...115,439,034
JBrowse link
G Decr1 2,4-dienoyl CoA reductase 1, mitochondrial multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in decreased expression of DECR1 mRNA CTD PMID:30611723 NCBI chr 4:15,917,240...15,945,377
Ensembl chr 4:15,917,240...15,945,507
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 decreases expression ISO Farnesol analog results in decreased expression of DGAT1 mRNA CTD PMID:30611723 NCBI chr15:76,502,012...76,512,021
Ensembl chr15:76,502,015...76,511,953
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of DGAT2 mRNA CTD PMID:30611723 NCBI chr 7:99,153,663...99,182,713
Ensembl chr 7:99,153,658...99,182,719
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO Farnesol results in increased expression of DNAJB4 mRNA CTD PMID:27965148 NCBI chr 3:152,181,580...152,210,432
Ensembl chr 3:152,178,511...152,210,302
JBrowse link
G Ech1 enoyl coenzyme A hydratase 1, peroxisomal increases expression ISO Farnesol analog results in increased expression of ECH1 mRNA CTD PMID:30611723 NCBI chr 7:28,825,338...28,832,239
Ensembl chr 7:28,825,217...28,832,247
JBrowse link
G Egf epidermal growth factor multiple interactions ISO Farnesol analog inhibits the reaction [EGF protein results in increased activity of RHOA protein]; Farnesol analog results in decreased susceptibility to [INS protein co-treated with EGF protein] CTD PMID:24587105 NCBI chr 3:129,677,574...129,755,322
Ensembl chr 3:129,677,565...129,755,316
JBrowse link
G Elovl6 ELOVL family member 6, elongation of long chain fatty acids (yeast) multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of ELOVL6 mRNA CTD PMID:30611723 NCBI chr 3:129,532,386...129,638,495
Ensembl chr 3:129,532,355...129,638,495
JBrowse link
G Fabp1 fatty acid binding protein 1, liver increases expression ISO Farnesol analog results in increased expression of FABP1 mRNA CTD PMID:30611723 NCBI chr 6:71,199,879...71,205,034
Ensembl chr 6:71,199,827...71,205,023
JBrowse link
G Fabp4 fatty acid binding protein 4, adipocyte increases expression ISO Farnesol results in increased expression of FABP4 mRNA CTD PMID:30806763 NCBI chr 3:10,204,342...10,208,616
Ensembl chr 3:10,204,088...10,208,576
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of FASN mRNA CTD PMID:30611723 NCBI chr11:120,805,958...120,825,166
Ensembl chr11:120,805,846...120,824,547
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression ISO Farnesol analog results in increased expression of FDFT1 mRNA CTD PMID:30611723 NCBI chr14:63,145,150...63,181,687
Ensembl chr14:63,145,150...63,179,578
JBrowse link
G Fnta farnesyltransferase, CAAX box, alpha multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of FNTA mRNA CTD PMID:30611723 NCBI chr 8:25,998,688...26,015,610
Ensembl chr 8:25,998,722...26,015,650
JBrowse link
G Fntb farnesyltransferase, CAAX box, beta decreases expression ISO Farnesol analog results in decreased expression of FNTB mRNA CTD PMID:30611723 NCBI chr12:76,837,400...76,921,412
Ensembl chr12:76,765,589...76,921,412
JBrowse link
G Gpat4 glycerol-3-phosphate acyltransferase 4 multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of GPAT4 mRNA CTD PMID:30611723 NCBI chr 8:23,171,265...23,208,453
Ensembl chr 8:23,171,265...23,208,346
JBrowse link
G Gsr glutathione reductase increases activity
increases expression
ISO Farnesol results in increased activity of GSR protein
Farnesol results in increased expression of GSR protein
CTD PMID:15840382 PMID:21453689 NCBI chr 8:33,653,238...33,698,162
Ensembl chr 8:33,652,523...33,698,163
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha multiple interactions
increases expression
ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of HADHA mRNA
Farnesol analog results in increased expression of HADHA mRNA
CTD PMID:30611723 NCBI chr 5:30,119,423...30,154,980
Ensembl chr 5:30,118,304...30,155,162
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta multiple interactions
increases expression
ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of HADHB mRNA
Farnesol analog results in increased expression of HADHB mRNA
CTD PMID:30611723 NCBI chr 5:30,155,253...30,184,593
Ensembl chr 5:30,155,248...30,184,593
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase multiple interactions
increases expression
decreases activity
ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of HMGCR mRNA
Farnesol results in increased expression of HMGCR protein
Farnesol results in decreased activity of HMGCR protein
CTD PMID:12477733 PMID:16332721 PMID:30611723 NCBI chr13:96,648,962...96,670,936
Ensembl chr13:96,648,967...96,670,936
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Farnesol results in increased expression of HMOX1 mRNA CTD PMID:30806763 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Hras Harvey rat sarcoma virus oncogene multiple interactions ISO Farnesol inhibits the reaction [Simvastatin results in decreased farnesylation of and affects the localization of HRAS protein] CTD PMID:12477733 NCBI chr 7:141,189,934...141,194,019
Ensembl chr 7:141,189,105...141,194,005
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Farnesol results in increased expression of ICAM1 mRNA CTD PMID:30806763 NCBI chr 9:21,015,940...21,028,814
Ensembl chr 9:21,015,985...21,028,817
JBrowse link
G Il16 interleukin 16 increases secretion ISO Farnesol results in increased secretion of IL16 protein CTD PMID:30806763 NCBI chr 7:83,642,819...83,746,028
Ensembl chr 7:83,642,825...83,745,726
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Farnesol results in increased expression of IL1A mRNA CTD PMID:30806763 NCBI chr 2:129,299,609...129,310,186
Ensembl chr 2:129,299,610...129,309,972
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
Farnesol inhibits the reaction [[Alendronate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]
Farnesol inhibits the reaction [[MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased expression of IL1B protein]
CTD PMID:20304105 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il1r2 interleukin 1 receptor, type II increases expression ISO Farnesol results in increased expression of IL1R2 mRNA CTD PMID:30806763 NCBI chr 1:40,084,692...40,125,230
Ensembl chr 1:40,074,079...40,125,231
JBrowse link
G Ins2 insulin II multiple interactions ISO Farnesol analog results in decreased susceptibility to [INS protein co-treated with EGF protein] CTD PMID:24587105 NCBI chr 7:142,678,656...142,679,726
Ensembl chr 7:142,678,656...142,743,381
JBrowse link
G Lipc lipase, hepatic increases expression ISO Farnesol analog results in increased expression of LIPC mRNA CTD PMID:30611723 NCBI chr 9:70,798,128...70,952,221
Ensembl chr 9:70,798,128...70,952,226
JBrowse link
G Lpin1 lipin 1 multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of LPIN1 mRNA CTD PMID:30611723 NCBI chr12:16,535,669...16,653,903
Ensembl chr12:16,535,669...16,646,966
JBrowse link
G Lpin3 lipin 3 decreases expression ISO Farnesol analog results in decreased expression of LPIN3 mRNA CTD PMID:30611723 NCBI chr 2:160,880,670...160,906,000
Ensembl chr 2:160,880,670...160,906,002
JBrowse link
G Mlxipl MLX interacting protein-like multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in decreased expression of MLXIPL mRNA CTD PMID:30611723 NCBI chr 5:135,089,890...135,139,768
Ensembl chr 5:135,089,890...135,138,382
JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression ISO Farnesol results in increased expression of MMP3 mRNA CTD PMID:30806763 NCBI chr 9:7,445,822...7,455,975
Ensembl chr 9:7,445,822...7,455,975
JBrowse link
G Mvk mevalonate kinase multiple interactions
decreases activity
ISO Farnesol inhibits the reaction [[MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased expression of IL1B protein]; Farnesol inhibits the reaction [MVK gene mutant form results in increased susceptibility to Lipopolysaccharides]; Farnesol inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; Farnesol inhibits the reaction [MVK protein results in increased phosphorylation of Mevalonic Acid]
Farnesol results in decreased activity of MVK protein
CTD PMID:9392419 PMID:20304105 NCBI chr 5:114,444,264...114,460,591
Ensembl chr 5:114,444,269...114,460,591
JBrowse link
G Myl9 myosin, light polypeptide 9, regulatory multiple interactions ISO Farnesol analog inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MYL9 protein] CTD PMID:24587105 NCBI chr 2:156,775,408...156,781,657
Ensembl chr 2:156,775,420...156,781,658
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 increases activity ISO Farnesol results in increased activity of NQO1 protein CTD PMID:15840382 NCBI chr 8:107,388,225...107,403,205
Ensembl chr 8:107,388,225...107,403,206
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression
multiple interactions
ISO Farnesol analog results in decreased expression of NR0B2 mRNA
[Farnesol analog co-treated with Oleic Acid] results in decreased expression of NR0B2 mRNA
CTD PMID:30611723 NCBI chr 4:133,553,376...133,556,686
Ensembl chr 4:133,553,376...133,556,536
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions
decreases expression
ISO Farnesol binds to and results in increased activity of NR1H4 protein
Farnesol analog results in decreased expression of NR1H4 mRNA
CTD PMID:15491415 PMID:30611723 NCBI chr10:89,454,234...89,533,645
Ensembl chr10:89,454,234...89,533,585
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic multiple interactions
decreases expression
ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of PCK1 mRNA
Farnesol analog results in decreased expression of PCK1 mRNA
CTD PMID:30611723 NCBI chr 2:173,153,073...173,159,274
Ensembl chr 2:173,153,048...173,159,273
JBrowse link
G Pdss1 prenyl (solanesyl) diphosphate synthase, subunit 1 increases expression ISO Farnesol analog results in increased expression of PDSS1 mRNA CTD PMID:30611723 NCBI chr 2:22,894,382...22,940,266
Ensembl chr 2:22,895,522...22,940,266
JBrowse link
G Plin2 perilipin 2 multiple interactions
increases expression
ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of PLIN2 mRNA
Farnesol analog results in increased expression of PLIN2 mRNA
CTD PMID:30611723 NCBI chr 4:86,626,910...86,670,217
Ensembl chr 4:86,648,386...86,670,060
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of PPARA mRNA; Farnesol inhibits the reaction [cerivastatin promotes the reaction [Bezafibrate results in increased activity of [PPARA protein binds to RXRA protein]]] CTD PMID:11779144 PMID:30611723 NCBI chr15:85,734,910...85,806,851
Ensembl chr15:85,734,983...85,802,819
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions
increases expression
ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of PPARG mRNA
Farnesol analog results in increased expression of PPARG mRNA
CTD PMID:30611723 NCBI chr 6:115,360,879...115,490,404
Ensembl chr 6:115,360,951...115,490,399
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha multiple interactions ISO Farnesol inhibits the reaction [Atorvastatin inhibits the reaction [TNF protein results in decreased expression of PPARGC1A protein]] CTD PMID:22343369 NCBI chr 5:51,454,249...52,115,853
Ensembl chr 5:51,454,250...51,567,726
JBrowse link
G Rabggta Rab geranylgeranyl transferase, a subunit multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in decreased expression of RABGGTA mRNA CTD PMID:30611723 NCBI chr14:55,715,864...55,722,263
Ensembl chr14:55,715,416...55,722,263
JBrowse link
G Rabggtb Rab geranylgeranyl transferase, b subunit multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in decreased expression of RABGGTB mRNA CTD PMID:30611723 NCBI chr 3:153,907,289...153,912,966
Ensembl chr 3:153,907,287...153,913,009
JBrowse link
G Rhoa ras homolog family member A multiple interactions ISO Farnesol inhibits the reaction [Lovastatin affects the localization of RHOA protein]
Farnesol analog inhibits the reaction [EGF protein results in increased activity of RHOA protein]; Farnesol analog inhibits the reaction [lysophosphatidic acid results in increased activity of RHOA protein]
CTD PMID:9398081 PMID:24587105 NCBI chr 9:108,306,160...108,337,943
Ensembl chr 9:108,306,129...108,337,934
JBrowse link
G Rhoc ras homolog family member C multiple interactions ISO Farnesol analog inhibits the reaction [lysophosphatidic acid results in increased activity of RHOC protein] CTD PMID:24587105 NCBI chr 3:104,789,034...104,794,459
Ensembl chr 3:104,788,375...104,794,459
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO Farnesol inhibits the reaction [cerivastatin promotes the reaction [Bezafibrate results in increased activity of [PPARA protein binds to RXRA protein]]] CTD PMID:11779144 NCBI chr 2:27,676,445...27,763,319
Ensembl chr 2:27,676,440...27,762,957
JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in decreased expression of SCD mRNA CTD PMID:30611723 NCBI chr19:44,293,676...44,306,864
Ensembl chr19:44,293,674...44,306,864
JBrowse link
G Scd3 stearoyl-coenzyme A desaturase 3 multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in decreased expression of SCD5 mRNA CTD PMID:30611723 NCBI chr19:44,203,288...44,244,016
Ensembl chr19:44,203,269...44,244,016
JBrowse link
G Serpinb3d serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3D increases expression ISO Farnesol results in increased expression of SERPINB3 mRNA CTD PMID:30806763 NCBI chr 1:107,078,163...107,083,480
Ensembl chr 1:107,078,167...107,083,506
JBrowse link
G Slc25a20 solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of SLC25A20 mRNA CTD PMID:30611723 NCBI chr 9:108,662,136...108,684,642
Ensembl chr 9:108,662,088...108,684,641
JBrowse link
G Slc27a1 solute carrier family 27 (fatty acid transporter), member 1 multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of SLC27A1 mRNA CTD PMID:30611723 NCBI chr 8:71,568,728...71,587,307
Ensembl chr 8:71,568,882...71,587,302
JBrowse link
G Slc27a2 solute carrier family 27 (fatty acid transporter), member 2 increases expression ISO Farnesol analog results in increased expression of SLC27A2 mRNA CTD PMID:30611723 NCBI chr 2:126,553,024...126,588,243
Ensembl chr 2:126,552,407...126,588,243
JBrowse link
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 increases expression ISO Farnesol results in increased expression of SLC7A11 mRNA CTD PMID:30806763 NCBI chr 3:50,364,936...50,499,087
Ensembl chr 3:49,892,526...50,443,614
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO Farnesol inhibits the reaction [Atorvastatin inhibits the reaction [TNF protein results in decreased expression of PPARGC1A protein]]
Farnesol results in increased expression of TNF mRNA
CTD PMID:22343369 PMID:30806763 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of Farnesol CTD PMID:15320866 NCBI chr 1:88,211,959...88,220,002
Ensembl chr 1:88,211,959...88,218,997
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of Farnesol CTD PMID:15320866 NCBI chr 1:88,200,611...88,220,002
Ensembl chr 1:88,200,601...88,218,997
JBrowse link
G Ugt1a5 UDP glucuronosyltransferase 1 family, polypeptide A5 increases glucuronidation ISO UGT1A4 protein results in increased glucuronidation of Farnesol CTD PMID:15320866 NCBI chr 1:88,166,012...88,220,002
Ensembl chr 1:88,166,012...88,218,997
JBrowse link
G Ugt1a6b UDP glucuronosyltransferase 1 family, polypeptide A6B increases glucuronidation ISO UGT1A6 protein results in increased glucuronidation of Farnesol CTD PMID:15320866 NCBI chr 1:88,103,257...88,218,998
Ensembl chr 1:88,103,252...88,219,003
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of Farnesol CTD PMID:15320866 NCBI chr 1:88,070,779...88,220,002
Ensembl chr 1:88,070,800...88,218,997
JBrowse link
G Ugt2b34 UDP glucuronosyltransferase 2 family, polypeptide B34 increases glucuronidation ISO UGT2B7 protein results in increased glucuronidation of Farnesol CTD PMID:15320866 NCBI chr 5:86,889,770...86,906,937
Ensembl chr 5:86,889,767...86,906,937
JBrowse link
farnesyl diphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Lovastatin results in decreased expression of BIRC5 protein] CTD PMID:17472962 NCBI chr11:117,849,237...117,855,743
Ensembl chr11:117,849,251...117,855,743
JBrowse link
G Bmp2 bone morphogenetic protein 2 multiple interactions EXP farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]] CTD PMID:18310456 NCBI chr 2:133,552,159...133,562,896
Ensembl chr 2:133,552,159...133,562,885
JBrowse link
G Casp3 caspase 3 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Lovastatin results in increased activity of and results in increased cleavage of CASP3 protein]
farnesyl pyrophosphate inhibits the reaction [Simvastatin results in increased activity of CASP3 protein]
CTD PMID:15200425 PMID:18766339 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CYP17A1 mRNA] CTD PMID:21918126 NCBI chr19:46,667,165...46,673,000
Ensembl chr19:46,667,165...46,673,172
JBrowse link
G Fnta farnesyltransferase, CAAX box, alpha multiple interactions ISO [FNTA protein binds to FNTB protein] binds to [farnesyl pyrophosphate analog co-treated with KRAS protein] CTD PMID:10673434 NCBI chr 8:25,998,688...26,015,610
Ensembl chr 8:25,998,722...26,015,650
JBrowse link
G Fntb farnesyltransferase, CAAX box, beta multiple interactions ISO [FNTA protein binds to FNTB protein] binds to [farnesyl pyrophosphate analog co-treated with KRAS protein] CTD PMID:10673434 NCBI chr12:76,837,400...76,921,412
Ensembl chr12:76,765,589...76,921,412
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of FOS mRNA] CTD PMID:16005304 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase multiple interactions ISO [Lovastatin results in decreased activity of HMGCR protein] which results in decreased abundance of farnesyl pyrophosphate CTD PMID:17208200 NCBI chr13:96,648,962...96,670,936
Ensembl chr13:96,648,967...96,670,936
JBrowse link
G Hras Harvey rat sarcoma virus oncogene multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased activity of HRAS protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased localization of HRAS protein]] CTD PMID:18625914 NCBI chr 7:141,189,934...141,194,019
Ensembl chr 7:141,189,105...141,194,005
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of ICAM1 protein]] CTD PMID:10946302 NCBI chr 9:21,015,940...21,028,814
Ensembl chr 9:21,015,985...21,028,817
JBrowse link
G Il12b interleukin 12b multiple interactions EXP farnesyl pyrophosphate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B protein] CTD PMID:15187114 NCBI chr11:44,400,063...44,414,677
Ensembl chr11:44,400,063...44,414,033
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of ICAM1 protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]] CTD PMID:10946302 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog multiple interactions ISO [FNTA protein binds to FNTB protein] binds to [farnesyl pyrophosphate analog co-treated with KRAS protein] CTD PMID:10673434 NCBI chr 6:145,216,699...145,250,420
Ensembl chr 6:145,216,699...145,250,239
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions EXP farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK1 protein]] CTD PMID:18310456 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions EXP farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK3 protein]] CTD PMID:18310456 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein]] CTD PMID:18310456 NCBI chr14:33,377,898...33,447,353
Ensembl chr14:33,377,898...33,447,158
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Smoke analog results in increased expression of MMP9 mRNA]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Smoke analog results in increased secretion of MMP9 protein]] CTD PMID:19299917 NCBI chr 2:164,940,326...164,955,850
Ensembl chr 2:164,940,780...164,955,850
JBrowse link
G Mvk mevalonate kinase decreases activity
decreases chemical synthesis
multiple interactions
ISO farnesyl pyrophosphate results in decreased activity of MVK protein
MVK protein mutant form results in decreased chemical synthesis of farnesyl pyrophosphate
farnesyl pyrophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; farnesyl pyrophosphate inhibits the reaction [MVK protein results in increased phosphorylation of Mevalonic Acid]
CTD PMID:9392419 PMID:24073415 NCBI chr 5:114,444,264...114,460,591
Ensembl chr 5:114,444,269...114,460,591
JBrowse link
G Pon1 paraoxonase 1 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [pitavastatin results in increased expression of PON1 mRNA]; farnesyl pyrophosphate inhibits the reaction [Simvastatin results in increased expression of PON1 mRNA] CTD PMID:14500290 PMID:15690306 NCBI chr 6:5,168,090...5,193,987
Ensembl chr 6:5,168,090...5,193,946
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased activity of RAC1 protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased localization of RAC1 protein]] CTD PMID:18625914 NCBI chr 5:143,505,481...143,528,031
Ensembl chr 5:143,503,634...143,528,036
JBrowse link
G Rhoa ras homolog family member A multiple interactions ISO
EXP
farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in decreased activity of RHOA protein]]
farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF affects the localization of RHOA protein]]
CTD PMID:18310456 PMID:18625914 NCBI chr 9:108,306,160...108,337,943
Ensembl chr 9:108,306,129...108,337,934
JBrowse link
G Runx2 runt related transcription factor 2 multiple interactions EXP farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]] CTD PMID:18310456 NCBI chr17:44,495,987...44,814,797
Ensembl chr17:44,495,987...44,814,797
JBrowse link
G Sele selectin, endothelial cell multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]] CTD PMID:10946302 NCBI chr 1:164,039,614...164,058,487
Ensembl chr 1:164,048,234...164,057,677
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF affects the localization of RHOA protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK1 protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK3 protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein]] CTD PMID:18310456 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
geraniol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 multiple interactions ISO geraniol inhibits the reaction [Fructose results in decreased expression of ABCC2 mRNA]; geraniol inhibits the reaction [Fructose results in decreased expression of ABCC2 protein] CTD PMID:31005848 NCBI chr19:43,782,308...43,838,332
Ensembl chr19:43,782,192...43,840,740
JBrowse link
G Acaca acetyl-Coenzyme A carboxylase alpha decreases expression EXP geraniol results in decreased expression of ACACA mRNA CTD PMID:26141755 NCBI chr11:84,129,635...84,401,651
Ensembl chr11:84,129,672...84,401,651
JBrowse link
G Ache acetylcholinesterase multiple interactions ISO geraniol inhibits the reaction [Acrylamide results in increased activity of ACHE protein]; geraniol inhibits the reaction [Streptozocin results in increased activity of ACHE protein] CTD PMID:24752916 PMID:25199698 NCBI chr 5:137,288,247...137,294,466
Ensembl chr 5:137,287,519...137,294,466
JBrowse link
G Acta2 actin, alpha 2, smooth muscle, aorta multiple interactions ISO geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ACTA2 mRNA] CTD PMID:26695085 NCBI chr19:34,240,336...34,255,585
Ensembl chr19:34,241,090...34,255,590
JBrowse link
G Actl6a actin-like 6A decreases expression ISO geraniol results in decreased expression of ACTL6A mRNA CTD PMID:27683099 NCBI chr 3:32,708,546...32,726,973
Ensembl chr 3:32,706,298...32,726,973
JBrowse link
G Acvr1 activin A receptor, type 1 increases expression ISO geraniol results in increased expression of ACVR1 mRNA CTD PMID:27683099 NCBI chr 2:58,446,438...58,566,828
Ensembl chr 2:58,388,644...58,567,157
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO geraniol inhibits the reaction [Fructose results in decreased secretion of ADIPOQ protein]; geraniol promotes the reaction [Streptozocin results in decreased expression of ADIPOQ protein] CTD PMID:25679220 PMID:28178614 NCBI chr16:23,146,536...23,157,968
Ensembl chr16:23,146,536...23,158,028
JBrowse link
G Aff4 AF4/FMR2 family, member 4 increases expression ISO geraniol results in increased expression of AFF4 mRNA CTD PMID:27683099 NCBI chr11:53,350,640...53,421,830
Ensembl chr11:53,350,833...53,421,830
JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions ISO geraniol inhibits the reaction [Fructose results in increased expression of AGER protein] CTD PMID:25679220 NCBI chr17:34,597,460...34,600,937
Ensembl chr17:34,597,862...34,600,936
JBrowse link
G Ahctf1 AT hook containing transcription factor 1 decreases expression ISO geraniol results in decreased expression of AHCTF1 mRNA CTD PMID:27683099 NCBI chr 1:179,744,904...179,804,015
Ensembl chr 1:179,744,894...179,803,680
JBrowse link
G Akr1c20 aldo-keto reductase family 1, member C20 increases expression ISO geraniol results in increased expression of AKR1C1 mRNA CTD PMID:30806763 NCBI chr13:4,486,856...4,523,354
Ensembl chr13:4,486,849...4,523,345
JBrowse link
G Ap5z1 adaptor-related protein complex 5, zeta 1 subunit increases expression ISO geraniol results in increased expression of AP5Z1 mRNA CTD PMID:27683099 NCBI chr 5:142,463,207...142,478,716
Ensembl chr 5:142,463,944...142,478,710
JBrowse link
G Apbb2 amyloid beta (A4) precursor protein-binding, family B, member 2 increases expression ISO geraniol results in increased expression of APBB2 mRNA CTD PMID:27683099 NCBI chr 5:66,298,725...66,619,064
Ensembl chr 5:66,298,703...66,618,784
JBrowse link
G Appl1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 decreases expression ISO geraniol results in decreased expression of APPL1 mRNA CTD PMID:27683099 NCBI chr14:26,918,986...26,970,611
Ensembl chr14:26,918,988...26,971,232
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like increases expression ISO geraniol results in increased expression of ARNTL mRNA CTD PMID:27683099 NCBI chr 7:113,178,471...113,314,126
Ensembl chr 7:113,207,465...113,314,126
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO geraniol results in increased expression of ATF3 mRNA CTD PMID:27683099 NCBI chr 1:191,170,296...191,183,333
Ensembl chr 1:191,170,296...191,218,039
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO geraniol inhibits the reaction [Rotenone results in increased expression of ATF4 protein] CTD PMID:30141137 NCBI chr15:80,255,184...80,257,545
Ensembl chr15:80,255,184...80,257,541
JBrowse link
G Atf6 activating transcription factor 6 increases expression
multiple interactions
ISO geraniol results in increased expression of ATF6 mRNA
geraniol inhibits the reaction [Rotenone results in increased expression of ATF6 protein]
CTD PMID:27683099 PMID:30141137 NCBI chr 1:170,704,457...170,868,585
Ensembl chr 1:170,704,674...170,867,771
JBrowse link
G Atg12 autophagy related 12 multiple interactions ISO geraniol inhibits the reaction [Rotenone results in decreased expression of ATG12 protein] CTD PMID:30141137 NCBI chr18:46,732,417...46,741,724
Ensembl chr18:46,730,144...46,741,580
JBrowse link
G Atg5 autophagy related 5 multiple interactions ISO geraniol inhibits the reaction [Rotenone results in decreased expression of ATG5 protein] CTD PMID:30141137 NCBI chr10:44,268,322...44,364,299
Ensembl chr10:44,268,358...44,364,291
JBrowse link
G Atg7 autophagy related 7 multiple interactions ISO geraniol inhibits the reaction [Rotenone results in decreased expression of ATG7 protein] CTD PMID:30141137 NCBI chr 6:114,643,127...114,860,604
Ensembl chr 6:114,643,097...114,860,614
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO geraniol results in increased expression of BAK1 protein CTD PMID:12530055 NCBI chr17:27,019,812...27,028,627
Ensembl chr17:27,019,810...27,029,009
JBrowse link
G Bax BCL2-associated X protein multiple interactions
increases expression
EXP
ISO
geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of BAX mRNA]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of BAX protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in decreased expression of BAX protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of BAX protein]
geraniol results in increased expression of BAX mRNA; geraniol results in increased expression of BAX protein
CTD PMID:21371438 PMID:22760862 PMID:24768735 PMID:29050341 PMID:29745075 PMID:30506710 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B decreases expression ISO geraniol results in decreased expression of BAZ1B mRNA CTD PMID:27683099 NCBI chr 5:135,187,323...135,246,131
Ensembl chr 5:135,187,264...135,246,129
JBrowse link
G Baz2b bromodomain adjacent to zinc finger domain, 2B increases expression ISO geraniol results in increased expression of BAZ2B mRNA CTD PMID:27683099 NCBI chr 2:59,899,363...60,209,913
Ensembl chr 2:59,899,363...60,209,839
JBrowse link
G Bbx bobby sox HMG box containing increases expression ISO geraniol results in increased expression of BBX mRNA CTD PMID:27683099 NCBI chr16:50,191,844...50,432,466
Ensembl chr16:50,191,844...50,432,390
JBrowse link
G Bcl11a B cell CLL/lymphoma 11A (zinc finger protein) decreases expression ISO geraniol results in decreased expression of BCL11A mRNA CTD PMID:27683099 NCBI chr11:24,076,564...24,173,558
Ensembl chr11:24,078,056...24,174,123
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions
decreases expression
increases expression
EXP
ISO
geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of BCL2 mRNA]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of BCL2 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of BCL2 protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of BCL2 protein]
geraniol results in decreased expression of BCL2 mRNA; geraniol results in decreased expression of BCL2 protein
geraniol results in increased expression of BCL2 protein
CTD PMID:21371438 PMID:21445532 PMID:22760862 PMID:24768735 PMID:29050341 PMID:29745075 PMID:30506710 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Bcl2l1 BCL2-like 1 multiple interactions ISO geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of BCL2L1 protein] CTD PMID:26695085 NCBI chr 2:152,758,732...152,833,803
Ensembl chr 2:152,780,668...152,831,728
JBrowse link
G Bcl2l2 BCL2-like 2 decreases expression ISO geraniol results in decreased expression of BCL2L2 protein CTD PMID:21371438 NCBI chr14:54,883,366...54,890,858
Ensembl chr14:54,892,500...54,898,169
Ensembl chr14:54,892,500...54,898,169
JBrowse link
G Bcl6 B cell leukemia/lymphoma 6 increases expression ISO geraniol results in increased expression of BCL6 mRNA CTD PMID:27683099 NCBI chr16:23,965,050...23,988,866
Ensembl chr16:23,965,052...23,988,852
JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 decreases expression ISO geraniol results in decreased expression of BCLAF1 mRNA CTD PMID:27683099 NCBI chr10:20,310,512...20,342,644
Ensembl chr10:20,312,469...20,344,613
JBrowse link
G Bdnf brain derived neurotrophic factor multiple interactions EXP geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BDNF mRNA]; geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BDNF protein] CTD PMID:23943375 NCBI chr 2:109,674,700...109,727,043
Ensembl chr 2:109,674,700...109,727,007
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO geraniol results in decreased expression of BIRC5 mRNA CTD PMID:27683099 NCBI chr11:117,849,237...117,855,743
Ensembl chr11:117,849,251...117,855,743
JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO geraniol results in increased expression of BMP6 mRNA CTD PMID:27683099 NCBI chr13:38,345,716...38,500,314
Ensembl chr13:38,345,107...38,500,302
JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 increases expression ISO geraniol results in increased expression of BNIP3 protein CTD PMID:21371438 NCBI chr 7:138,890,836...138,909,506
Ensembl chr 7:138,890,836...138,909,519
JBrowse link
G Brca1 breast cancer 1, early onset decreases expression ISO geraniol results in decreased expression of BRCA1 mRNA CTD PMID:27683099 NCBI chr11:101,488,761...101,551,955
Ensembl chr11:101,488,764...101,551,955
JBrowse link
G Brca2 breast cancer 2, early onset decreases expression ISO geraniol results in decreased expression of BRCA2 mRNA CTD PMID:27683099 NCBI chr 5:150,522,297...150,570,147
Ensembl chr 5:150,522,630...150,570,329
JBrowse link
G Btf3 basic transcription factor 3 decreases expression ISO geraniol results in decreased expression of BTF3 mRNA CTD PMID:27683099 NCBI chr13:98,309,897...98,317,006
Ensembl chr13:98,309,896...98,317,006
JBrowse link
G Bub1 BUB1, mitotic checkpoint serine/threonine kinase decreases expression ISO geraniol results in decreased expression of BUB1 mRNA CTD PMID:27683099 NCBI chr 2:127,800,197...127,831,859
Ensembl chr 2:127,801,122...127,831,865
JBrowse link
G Bub1b BUB1B, mitotic checkpoint serine/threonine kinase decreases expression ISO geraniol results in decreased expression of BUB1B mRNA CTD PMID:27683099 NCBI chr 2:118,598,202...118,641,592
Ensembl chr 2:118,598,211...118,641,591
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
ISO
EXP
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased cleavage of CASP3 protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of CASP3 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP3 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP3 mRNA]; geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased activity of CASP3 protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein]
geraniol results in increased expression of CASP3 mRNA; geraniol results in increased expression of CASP3 protein
geraniol results in increased activity of CASP3 protein
geraniol results in increased expression of CASP3 protein modified form
geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CASP3 protein]
CTD PMID:21371438 PMID:21907755 PMID:22509279 PMID:24875281 PMID:26154255 PMID:26165751 PMID:26364502 PMID:26695085 PMID:29050341 PMID:30506710 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp8 caspase 8 multiple interactions
increases expression
ISO geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP8 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP8 mRNA]
geraniol results in increased expression of CASP8 mRNA; geraniol results in increased expression of CASP8 protein
CTD PMID:21907755 PMID:30506710 NCBI chr 1:58,795,233...58,847,503
Ensembl chr 1:58,795,374...58,847,503
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
ISO
EXP
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased cleavage of CASP9 protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of CASP9 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP9 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP9 mRNA]; geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased activity of CASP9 protein]
geraniol results in increased expression of CASP9 mRNA; geraniol results in increased expression of CASP9 protein
geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CASP9 mRNA]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CASP9 protein]
CTD PMID:21907755 PMID:22509279 PMID:24768735 PMID:26364502 PMID:26695085 PMID:30506710 NCBI chr 4:141,793,612...141,815,978
Ensembl chr 4:141,793,612...141,815,976
JBrowse link
G Cat catalase multiple interactions
decreases activity
increases activity
EXP
ISO
geraniol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CAT protein]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased activity of CAT protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CAT protein]
geraniol results in decreased activity of CAT protein
geraniol results in increased activity of CAT protein
geraniol inhibits the reaction [2-Acetylaminofluorene results in decreased activity of CAT protein]; geraniol inhibits the reaction [ferric nitrilotriacetate results in decreased activity of CAT protein]; geraniol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]
CTD PMID:21907755 PMID:22760862 PMID:23033690 PMID:23399806 PMID:24752916 PMID:24768735 PMID:25574396 PMID:26364502 PMID:28178614 PMID:32119866 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Cbfa2t2 CBFA2/RUNX1 translocation partner 2 increases expression ISO geraniol results in increased expression of CBFA2T2 mRNA CTD PMID:27683099 NCBI chr 2:154,436,098...154,539,356
Ensembl chr 2:154,436,481...154,539,356
JBrowse link
G Cbfb core binding factor beta decreases expression ISO geraniol results in decreased expression of CBFB mRNA CTD PMID:27683099 NCBI chr 8:105,170,674...105,217,989
Ensembl chr 8:105,170,674...105,217,989
JBrowse link
G Ccl4 chemokine (C-C motif) ligand 4 increases secretion ISO geraniol results in increased secretion of CCL4 protein CTD PMID:30806763 NCBI chr11:83,648,624...83,664,683
Ensembl chr11:83,662,584...83,664,683
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO geraniol results in decreased expression of CCNA2 mRNA; geraniol results in decreased expression of CCNA2 protein CTD PMID:17138864 PMID:27683099 NCBI chr 3:36,564,865...36,573,038
Ensembl chr 3:36,564,865...36,572,150
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO geraniol results in decreased expression of CCNB1 protein CTD PMID:17138864 PMID:21371438 NCBI chr13:100,778,739...100,786,486
Ensembl chr13:100,778,650...100,786,570
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO geraniol results in decreased expression of CCND1 protein CTD PMID:15450939 NCBI chr 7:144,929,931...144,939,831
Ensembl chr 7:144,929,931...144,939,925
JBrowse link
G Cd3eap CD3E antigen, epsilon polypeptide associated protein decreases expression ISO geraniol results in decreased expression of POLR1G mRNA CTD PMID:27683099 NCBI chr 7:19,356,007...19,359,483
Ensembl chr 7:19,356,014...19,359,483
JBrowse link
G Cd86 CD86 antigen increases expression ISO geraniol results in increased expression of CD86 protein CTD PMID:30806763 NCBI chr16:36,568,956...36,666,158
Ensembl chr16:36,603,869...36,666,081
JBrowse link
G Cdc20 cell division cycle 20 decreases expression ISO geraniol results in decreased expression of CDC20 mRNA CTD PMID:27683099 NCBI chr 4:118,432,901...118,437,343
Ensembl chr 4:118,432,901...118,437,352
JBrowse link
G Cdc25a cell division cycle 25A decreases expression ISO geraniol results in decreased expression of CDC25A mRNA CTD PMID:27683099 NCBI chr 9:109,875,518...109,893,895
Ensembl chr 9:109,875,579...109,893,895
JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO geraniol results in decreased expression of CDC25C mRNA CTD PMID:27683099 NCBI chr18:34,732,993...34,751,564
Ensembl chr18:34,732,993...34,751,533
JBrowse link
G Cdc45 cell division cycle 45 decreases expression ISO geraniol results in decreased expression of CDC45 mRNA CTD PMID:27683099 NCBI chr16:18,780,447...18,811,972
Ensembl chr16:18,780,447...18,811,987
JBrowse link
G Cdc7 cell division cycle 7 (S. cerevisiae) decreases expression ISO geraniol results in decreased expression of CDC7 mRNA CTD PMID:27683099 NCBI chr 5:106,964,315...106,984,440
Ensembl chr 5:106,964,322...106,984,432
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 protein] CTD PMID:28428697 NCBI chr 8:106,603,350...106,670,247
Ensembl chr 8:106,603,351...106,670,246
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO geraniol results in decreased expression of CDK1 protein CTD PMID:21371438 NCBI chr10:69,335,146...69,352,912
Ensembl chr10:69,335,146...69,352,938
JBrowse link
G Cdk2 cyclin-dependent kinase 2 decreases expression
multiple interactions
ISO geraniol results in decreased expression of CDK2 mRNA; geraniol results in decreased expression of CDK2 protein
geraniol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein]; geraniol promotes the reaction [CDKN1B protein binds to and results in decreased activity of CDK2 protein]
CTD PMID:15450939 PMID:17138864 PMID:27683099 NCBI chr10:128,697,938...128,705,051
Ensembl chr10:128,697,939...128,705,031
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO geraniol results in decreased expression of CDK4 protein CTD PMID:15450939 PMID:21371438 NCBI chr10:127,063,535...127,067,288
Ensembl chr10:127,063,534...127,067,920
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) increases response to substance
increases expression
multiple interactions
ISO CDKN1A protein results in increased susceptibility to geraniol
geraniol results in increased expression of CDKN1A protein
geraniol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein]
CTD PMID:17138864 PMID:21371438 NCBI chr17:29,090,979...29,100,722
Ensembl chr17:29,090,976...29,100,727
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression
multiple interactions
increases response to substance
ISO geraniol results in increased expression of CDKN1B protein
geraniol promotes the reaction [CDKN1B protein binds to and results in decreased activity of CDK2 protein]
CDKN1B protein results in increased susceptibility to geraniol
CTD PMID:17138864 PMID:21371438 NCBI chr 6:134,920,401...134,925,525
Ensembl chr 6:134,920,401...134,925,513
JBrowse link
G Cdkn2c cyclin dependent kinase inhibitor 2C decreases expression ISO geraniol results in decreased expression of CDKN2C mRNA CTD PMID:27683099 NCBI chr 4:109,660,876...109,666,756
Ensembl chr 4:109,660,876...109,667,189
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression ISO geraniol results in decreased expression of CDKN3 mRNA CTD PMID:27683099 NCBI chr14:46,760,461...46,771,530
Ensembl chr14:46,760,541...46,771,669
JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 decreases expression ISO geraniol results in decreased expression of CDT1 mRNA CTD PMID:27683099 NCBI chr 8:122,568,015...122,573,130
Ensembl chr 8:122,568,015...122,573,554
JBrowse link
G Cebpb CCAAT/enhancer binding protein (C/EBP), beta increases expression ISO geraniol results in increased expression of CEBPB mRNA CTD PMID:27683099 NCBI chr 2:167,688,915...167,690,432
Ensembl chr 2:167,688,915...167,690,418
JBrowse link
G Cebpg CCAAT/enhancer binding protein (C/EBP), gamma increases expression ISO geraniol results in increased expression of CEBPG mRNA CTD PMID:27683099 NCBI chr 7:35,046,422...35,056,566
Ensembl chr 7:35,046,422...35,056,573
JBrowse link
G Cenpe centromere protein E decreases expression ISO geraniol results in decreased expression of CENPE mRNA CTD PMID:27683099 NCBI chr 3:135,212,563...135,273,540
Ensembl chr 3:135,212,537...135,273,611
JBrowse link
G Cenpf centromere protein F decreases expression ISO geraniol results in decreased expression of CENPF mRNA CTD PMID:27683099 NCBI chr 1:189,640,606...189,688,107
Ensembl chr 1:189,640,606...189,688,086
JBrowse link
G Chek1 checkpoint kinase 1 decreases expression ISO geraniol results in decreased expression of CHEK1 mRNA CTD PMID:27683099 NCBI chr 9:36,708,482...36,726,658
Ensembl chr 9:36,708,482...36,727,065
JBrowse link
G Cit citron decreases expression ISO geraniol results in decreased expression of CIT mRNA CTD PMID:27683099 NCBI chr 5:115,845,224...116,008,953
Ensembl chr 5:115,845,278...116,008,947
JBrowse link
G Cnbp cellular nucleic acid binding protein decreases expression ISO geraniol results in decreased expression of CNBP mRNA CTD PMID:27683099 NCBI chr 6:87,842,615...87,851,106
Ensembl chr 6:87,842,615...87,851,106
JBrowse link
G Cnga2 cyclic nucleotide gated channel alpha 2 multiple interactions ISO CNGA2 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein] CTD PMID:29070885 NCBI chr  X:71,991,849...72,010,218
Ensembl chr  X:71,991,849...72,010,218
JBrowse link
G Col1a1 collagen, type I, alpha 1 multiple interactions ISO geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA] CTD PMID:26695085 NCBI chr11:94,936,224...94,953,042
Ensembl chr11:94,936,224...94,953,042
JBrowse link
G Cox7c cytochrome c oxidase subunit 7C multiple interactions EXP geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of COX7C mRNA] CTD PMID:24768735 NCBI chr13:86,044,798...86,046,795
Ensembl chr13:86,044,816...86,046,904
JBrowse link
G Creb3 cAMP responsive element binding protein 3 increases expression ISO geraniol results in increased expression of CREB3 mRNA CTD PMID:27683099 NCBI chr 4:43,562,658...43,567,061
Ensembl chr 4:43,562,332...43,567,060
JBrowse link
G Creb3l2 cAMP responsive element binding protein 3-like 2 increases expression ISO geraniol results in increased expression of CREB3L2 mRNA CTD PMID:27683099 NCBI chr 6:37,327,255...37,442,276
Ensembl chr 6:37,327,255...37,442,146
JBrowse link
G Ctnnb1 catenin (cadherin associated protein), beta 1 multiple interactions ISO geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CTNNB1 mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 protein] CTD PMID:26165751 PMID:28428697 NCBI chr 9:120,933,400...120,960,507
Ensembl chr 9:120,929,216...120,960,507
JBrowse link
G Ctsd cathepsin D multiple interactions ISO geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased activity of CTSD protein] CTD PMID:23499697 NCBI chr 7:142,375,910...142,387,827
Ensembl chr 7:142,375,911...142,388,038
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 increases expression
increases secretion
ISO geraniol results in increased expression of CXCL8 mRNA
geraniol results in increased secretion of CXCL8 protein
CTD PMID:20713136 PMID:21920952 PMID:30806763 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Cyb5a cytochrome b5 type A (microsomal) multiple interactions ISO geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased activity of CYB5A protein] CTD PMID:23499697 NCBI chr18:84,851,338...84,879,871
Ensembl chr18:84,838,704...84,879,871
JBrowse link
G Cybb cytochrome b-245, beta polypeptide multiple interactions ISO
EXP
geraniol inhibits the reaction [Palmitic Acid results in increased expression of CYBB protein]
geraniol inhibits the reaction [Dietary Fats results in increased expression of CYBB protein]
CTD PMID:27107694 NCBI chr  X:9,435,252...9,487,766
Ensembl chr  X:9,435,252...9,487,771
JBrowse link
G Cyc1 cytochrome c-1 multiple interactions EXP geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CYC1 protein] CTD PMID:24768735 NCBI chr15:76,343,513...76,346,260
Ensembl chr15:76,343,523...76,346,260
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases metabolic processing
multiple interactions
ISO CYP1A1 protein results in increased metabolism of geraniol
[[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol; [CYP1A1 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [CYP1A1 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite
CTD PMID:18824010 NCBI chr 9:57,687,928...57,703,824
Ensembl chr 9:57,687,928...57,703,824
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol CTD PMID:18824010 NCBI chr17:79,706,940...79,715,061
Ensembl chr17:79,701,537...79,715,061
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 multiple interactions
increases metabolic processing
ISO [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol; [CYP2B6 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; geraniol inhibits the reaction [CYP2B6 protein results in increased hydrolysis of Bupropion] CTD PMID:18611395 PMID:18824010 NCBI chr 7:25,897,658...25,926,624
Ensembl chr 7:25,897,620...25,926,624
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CYP2E1 protein]
[[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol
CTD PMID:18824010 PMID:26695085 NCBI chr 7:140,763,819...140,774,990
Ensembl chr 7:140,763,739...140,774,987
JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 increases metabolic processing
multiple interactions
ISO CYP3A5 protein results in increased metabolism of geraniol
[[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol; [CYP3A5 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [CYP3A5 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite
CTD PMID:18824010 NCBI chr 5:145,854,607...145,879,854
Ensembl chr 5:145,854,426...145,879,964
JBrowse link
G Dbf4 DBF4 zinc finger decreases expression ISO geraniol results in decreased expression of DBF4 mRNA CTD PMID:27683099 NCBI chr 5:8,396,969...8,422,725
Ensembl chr 5:8,396,973...8,422,716
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO geraniol results in increased expression of DDIT3 mRNA
geraniol inhibits the reaction [Rotenone results in increased expression of DDIT3 protein]
CTD PMID:27683099 PMID:30141137 NCBI chr10:127,290,793...127,296,291
Ensembl chr10:127,290,774...127,296,288
Ensembl chr10:127,290,774...127,296,288
JBrowse link
G Dek DEK proto-oncogene (DNA binding) decreases expression ISO geraniol results in decreased expression of DEK mRNA CTD PMID:27683099 NCBI chr13:47,084,767...47,107,530
Ensembl chr13:47,084,775...47,106,201
JBrowse link
G Dmtf1 cyclin D binding myb-like transcription factor 1 increases expression ISO geraniol results in increased expression of DMTF1 mRNA CTD PMID:27683099 NCBI chr 5:9,118,868...9,161,806
Ensembl chr 5:9,118,801...9,161,776
JBrowse link
G Dnajc1 DnaJ heat shock protein family (Hsp40) member C1 increases expression ISO geraniol results in increased expression of DNAJC1 mRNA CTD PMID:27683099 NCBI chr 2:18,205,634...18,394,099
Ensembl chr 2:18,195,654...18,392,830
JBrowse link
G Dr1 down-regulator of transcription 1 decreases expression ISO geraniol results in decreased expression of DR1 mRNA CTD PMID:27683099 NCBI chr 5:108,268,897...108,280,521
Ensembl chr 5:108,268,897...108,280,526
JBrowse link
G Dtymk deoxythymidylate kinase decreases expression ISO geraniol results in decreased expression of DTYMK mRNA CTD PMID:27683099 NCBI chr 1:93,792,576...93,802,068
Ensembl chr 1:93,792,576...93,801,934
JBrowse link
G E2f1 E2F transcription factor 1 decreases expression ISO geraniol results in decreased expression of E2F1 mRNA CTD PMID:27683099 NCBI chr 2:154,559,400...154,569,892
Ensembl chr 2:154,559,407...154,569,892
JBrowse link
G E2f8 E2F transcription factor 8 decreases expression ISO geraniol results in decreased expression of E2F8 mRNA; geraniol results in decreased expression of E2F8 protein CTD PMID:27683099 NCBI chr 7:48,866,429...48,882,073
Ensembl chr 7:48,866,429...48,881,596
JBrowse link
G Ehf ets homologous factor decreases expression ISO geraniol results in decreased expression of EHF mRNA CTD PMID:27683099 NCBI chr 2:103,263,431...103,303,275
Ensembl chr 2:103,263,433...103,303,278
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions ISO geraniol inhibits the reaction [Rotenone results in increased expression of EIF2AK3 protein] CTD PMID:30141137 NCBI chr 6:70,844,484...70,905,241
Ensembl chr 6:70,844,515...70,905,245
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha multiple interactions ISO geraniol inhibits the reaction [Rotenone results in increased expression of EIF2S1 protein] CTD PMID:30141137 NCBI chr12:78,862,072...78,887,010
Ensembl chr12:78,861,819...78,887,010
JBrowse link
G Elavl2 ELAV like RNA binding protein 1 decreases expression ISO geraniol results in decreased expression of ELAVL2 mRNA CTD PMID:27683099 NCBI chr 4:91,211,533...91,400,108
Ensembl chr 4:91,250,763...91,400,785
JBrowse link
G Elf1 E74 like ETS transcription factor 1 increases expression ISO geraniol results in increased expression of ELF1 mRNA CTD PMID:27683099 NCBI chr14:79,481,174...79,582,491
Ensembl chr14:79,481,194...79,582,494
JBrowse link
G Elk4 ELK4, member of ETS oncogene family increases expression ISO geraniol results in increased expression of ELK4 mRNA CTD PMID:27683099 NCBI chr 1:132,007,577...132,026,448
Ensembl chr 1:132,007,607...132,032,612
JBrowse link
G Erc1 ELKS/RAB6-interacting/CAST family member 1 increases expression ISO geraniol results in increased expression of ERC1 mRNA CTD PMID:27683099 NCBI chr 6:119,570,796...119,848,184
Ensembl chr 6:119,570,796...119,848,167
JBrowse link
G Ern1 endoplasmic reticulum (ER) to nucleus signalling 1 multiple interactions ISO geraniol inhibits the reaction [Rotenone results in increased expression of ERN1 protein] CTD PMID:30141137 NCBI chr11:106,397,620...106,487,796
Ensembl chr11:106,394,650...106,487,852
JBrowse link
G Espl1 extra spindle pole bodies 1, separase decreases expression ISO geraniol results in decreased expression of ESPL1 mRNA CTD PMID:27683099 NCBI chr15:102,296,254...102,324,357
Ensembl chr15:102,296,266...102,324,357
JBrowse link
G Esr1 estrogen receptor 1 (alpha) affects binding
multiple interactions
ISO geraniol binds to ESR1 protein
geraniol inhibits the reaction [Estradiol binds to ESR1 protein]
CTD PMID:12495555 NCBI chr10:4,611,989...5,005,633
Ensembl chr10:4,611,593...5,005,614
JBrowse link
G Esr2 estrogen receptor 2 (beta) affects binding
multiple interactions
ISO geraniol binds to ESR2 protein
geraniol inhibits the reaction [Estradiol binds to ESR2 protein]
CTD PMID:12495555 NCBI chr12:76,120,419...76,177,259
Ensembl chr12:76,120,419...76,177,259
JBrowse link
G Ets2 E26 avian leukemia oncogene 2, 3' domain increases expression ISO geraniol results in increased expression of ETS2 mRNA CTD PMID:27683099 NCBI chr16:95,702,407...95,721,049
Ensembl chr16:95,702,075...95,721,051
JBrowse link
G Etv1 ets variant 1 decreases expression ISO geraniol results in decreased expression of ETV1 mRNA CTD PMID:27683099 NCBI chr12:38,780,082...38,870,483
Ensembl chr12:38,779,380...38,870,484
JBrowse link
G Ewsr1 Ewing sarcoma breakpoint region 1 decreases expression ISO geraniol results in decreased expression of EWSR1 mRNA CTD PMID:27683099 NCBI chr11:5,069,687...5,099,107
Ensembl chr11:5,069,689...5,099,266
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit decreases expression ISO geraniol results in decreased expression of EZH2 mRNA CTD PMID:27683099 NCBI chr 6:47,530,274...47,595,270
Ensembl chr 6:47,530,139...47,595,341
JBrowse link
G Fabp4 fatty acid binding protein 4, adipocyte increases expression ISO geraniol results in increased expression of FABP4 mRNA CTD PMID:30806763 NCBI chr 3:10,204,342...10,208,616
Ensembl chr 3:10,204,088...10,208,576
JBrowse link
G Fads1 fatty acid desaturase 1 decreases activity
multiple interactions
ISO geraniol results in decreased activity of FADS1 protein
[geraniol results in decreased activity of FADS1 protein] which results in decreased chemical synthesis of Arachidonic Acid; [geraniol results in decreased activity of FADS1 protein] which results in decreased metabolism of 8,11,14-Eicosatrienoic Acid
CTD PMID:16462894 NCBI chr19:10,182,877...10,196,874
Ensembl chr19:10,182,888...10,196,877
JBrowse link
G Fancg Fanconi anemia, complementation group G decreases expression ISO geraniol results in decreased expression of FANCG mRNA CTD PMID:27683099 NCBI chr 4:43,002,337...43,010,567
Ensembl chr 4:43,002,343...43,010,506
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO geraniol promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of FASN mRNA] CTD PMID:26695085 NCBI chr11:120,805,958...120,825,166
Ensembl chr11:120,805,846...120,824,547
JBrowse link
G Fbxo5 F-box protein 5 decreases expression ISO geraniol results in decreased expression of FBXO5 mRNA CTD PMID:27683099 NCBI chr10:5,799,158...5,805,465
Ensembl chr10:5,799,160...5,805,600
JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression ISO geraniol results in increased expression of FOS mRNA CTD PMID:27683099 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273
JBrowse link
G Fosl1 fos-like antigen 1 decreases expression ISO geraniol results in decreased expression of FOSL1 mRNA CTD PMID:27683099 NCBI chr19:5,447,698...5,455,938
Ensembl chr19:5,447,547...5,455,946
JBrowse link
G Fosl2 fos-like antigen 2 increases expression ISO geraniol results in increased expression of FOSL2 mRNA CTD PMID:27683099 NCBI chr 5:32,136,472...32,157,840
Ensembl chr 5:32,135,801...32,157,842
JBrowse link
G Foxa2 forkhead box A2 decreases expression ISO geraniol results in decreased expression of FOXA2 mRNA CTD PMID:27683099 NCBI chr 2:148,042,877...148,046,969
Ensembl chr 2:148,042,877...148,046,969
JBrowse link
G Foxj3 forkhead box J3 increases expression ISO geraniol results in increased expression of FOXJ3 mRNA CTD PMID:27683099 NCBI chr 4:119,539,661...119,629,119
Ensembl chr 4:119,537,004...119,629,119
JBrowse link
G Foxm1 forkhead box M1 decreases expression ISO geraniol results in decreased expression of FOXM1 mRNA CTD PMID:27683099 NCBI chr 6:128,362,994...128,375,886
Ensembl chr 6:128,362,967...128,376,146
JBrowse link
G Foxo4 forkhead box O4 increases expression ISO geraniol results in increased expression of FOXO4 mRNA CTD PMID:27683099 NCBI chr  X:101,254,261...101,260,873
Ensembl chr  X:101,254,528...101,260,873
JBrowse link
G Fst follistatin increases expression ISO geraniol results in increased expression of FST mRNA CTD PMID:27683099 NCBI chr13:114,452,262...114,458,989
Ensembl chr13:114,452,290...114,458,951
JBrowse link
G Fubp1 far upstream element (FUSE) binding protein 1 decreases expression ISO geraniol results in decreased expression of FUBP1 mRNA CTD PMID:27683099 NCBI chr 3:152,210,422...152,236,830
Ensembl chr 3:152,210,422...152,236,826
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked multiple interactions EXP
ISO
geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of G6PD protein]
geraniol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]
CTD PMID:23399806 PMID:28330423 NCBI chr  X:74,409,483...74,428,880
Ensembl chr  X:74,409,483...74,429,194
JBrowse link
G Gatad1 GATA zinc finger domain containing 1 increases expression ISO geraniol results in increased expression of GATAD1 mRNA CTD PMID:27683099 NCBI chr 5:3,639,961...3,647,936
Ensembl chr 5:3,632,932...3,657,185
JBrowse link
G Gbx2 gastrulation brain homeobox 2 decreases expression ISO geraniol results in decreased expression of GBX2 mRNA CTD PMID:27683099 NCBI chr 1:89,927,962...89,931,176
Ensembl chr 1:89,927,956...89,931,179
JBrowse link
G Gcg glucagon increases secretion
multiple interactions
EXP
ISO
geraniol results in increased secretion of GCG protein
9-(tetrahydro-2-furyl)-adenine inhibits the reaction [geraniol results in increased secretion of GCG protein]; CNGA2 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein]; GNAL mRNA promotes the reaction [geraniol results in increased secretion of GCG protein]; OR1A1 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein]; OR1G1 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein]
CTD PMID:29070885 NCBI chr 2:62,474,530...62,483,653
Ensembl chr 2:62,474,530...62,483,650
JBrowse link
G Gdnf glial cell line derived neurotrophic factor multiple interactions EXP geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of GDNF mRNA]; geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of GDNF protein] CTD PMID:23943375 NCBI chr15:7,810,048...7,837,580
Ensembl chr15:7,810,846...7,837,575
JBrowse link
G Gmnn geminin decreases expression ISO geraniol results in decreased expression of GMNN mRNA CTD PMID:27683099 NCBI chr13:24,751,845...24,761,937
Ensembl chr13:24,751,845...24,761,923
JBrowse link
G Gna15 guanine nucleotide binding protein, alpha 15 increases response to substance
multiple interactions
ISO GNA15 protein results in increased susceptibility to geraniol
[GNA15 protein results in increased susceptibility to geraniol] which results in increased activity of OLFR43 protein
CTD PMID:15598656 NCBI chr10:81,502,313...81,524,447
Ensembl chr10:81,502,306...81,524,225
JBrowse link
G Gnal guanine nucleotide binding protein, alpha stimulating, olfactory type multiple interactions
increases response to substance
ISO [GNAL protein results in increased susceptibility to geraniol] which results in increased activity of OLFR43 protein; GNAL mRNA promotes the reaction [geraniol results in increased secretion of GCG protein] CTD PMID:15598656 PMID:29070885 NCBI chr18:67,088,298...67,226,792
Ensembl chr18:67,088,216...67,226,792
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of GPX1 mRNA] CTD PMID:22509279 NCBI chr 9:108,339,080...108,340,342
Ensembl chr 9:108,338,903...108,340,343
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein] CTD PMID:26165751 NCBI chr16:38,089,001...38,246,084
Ensembl chr16:38,089,001...38,246,084
JBrowse link
G Gsr glutathione reductase multiple interactions
decreases activity
EXP
ISO
geraniol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of GSR protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GSR protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of GSR protein]
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased activity of GSR protein]; [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of GSR mRNA]; geraniol inhibits the reaction [2-Acetylaminofluorene results in decreased activity of GSR protein]; geraniol inhibits the reaction [Streptozocin affects the activity of GSR protein]
geraniol results in decreased activity of GSR protein
CTD PMID:22509279 PMID:22760862 PMID:23033690 PMID:23399806 PMID:24752916 PMID:26364502 PMID:28817314 NCBI chr 8:33,653,238...33,698,162
Ensembl chr 8:33,652,523...33,698,163
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 multiple interactions ISO geraniol inhibits the reaction [Diethylnitrosamine results in increased expression of GSTP1 protein] CTD PMID:27046949 NCBI chr19:4,035,411...4,037,912
Ensembl chr19:4,035,407...4,037,985
JBrowse link
G Gtf2b general transcription factor IIB increases expression ISO geraniol results in increased expression of GTF2B mRNA CTD PMID:27683099 NCBI chr 3:142,765,247...142,783,606
Ensembl chr 3:142,765,045...142,783,606
JBrowse link
G Gtf2h1 general transcription factor II H, polypeptide 1 increases expression ISO geraniol results in increased expression of GTF2H1 mRNA CTD PMID:27683099 NCBI chr 7:46,796,094...46,823,800
Ensembl chr 7:46,796,103...46,823,800
JBrowse link
G Gtf2ird1 general transcription factor II I repeat domain-containing 1 increases expression ISO geraniol results in increased expression of GTF2IRD1 mRNA CTD PMID:27683099 NCBI chr 5:134,357,661...134,456,867
Ensembl chr 5:134,357,656...134,456,716
JBrowse link
G Gtf3a general transcription factor III A decreases expression ISO geraniol results in decreased expression of GTF3A mRNA CTD PMID:27683099 NCBI chr 5:146,948,657...146,955,614
Ensembl chr 5:146,948,657...146,955,614
JBrowse link
G Gtf3c1 general transcription factor III C 1 increases expression ISO geraniol results in increased expression of GTF3C1 mRNA CTD PMID:27683099 NCBI chr 7:125,640,954...125,707,688
Ensembl chr 7:125,640,954...125,707,780
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions ISO geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of HAVCR1 mRNA]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of HAVCR1 protein] CTD PMID:21907755 NCBI chr11:46,739,822...46,779,578
Ensembl chr11:46,735,080...46,779,578
JBrowse link
G Hbb-b1 hemoglobin, beta adult major chain multiple interactions ISO geraniol inhibits the reaction [Fructose promotes the reaction [Glucose binds to HBB protein]] CTD PMID:25679220
G Hbp1 high mobility group box transcription factor 1 increases expression ISO geraniol results in increased expression of HBP1 mRNA CTD PMID:27683099 NCBI chr12:31,926,452...31,950,530
Ensembl chr12:31,926,254...31,950,535
JBrowse link
G Hivep1 human immunodeficiency virus type I enhancer binding protein 1 increases expression ISO geraniol results in increased expression of HIVEP1 mRNA CTD PMID:27683099 NCBI chr13:42,051,899...42,185,030
Ensembl chr13:42,052,021...42,192,537
JBrowse link
G Hlf hepatic leukemia factor decreases expression ISO geraniol results in decreased expression of HLF mRNA CTD PMID:27683099 NCBI chr11:90,336,535...90,390,917
Ensembl chr11:90,336,536...90,390,895
JBrowse link
G Hmbox1 homeobox containing 1 increases expression ISO geraniol results in increased expression of HMBOX1 mRNA CTD PMID:27683099 NCBI chr14:64,811,600...64,949,899
Ensembl chr14:64,811,600...64,949,871
JBrowse link
G Hmg20b high mobility group 20B decreases expression ISO geraniol results in decreased expression of HMG20B mRNA CTD PMID:27683099 NCBI chr10:81,346,046...81,350,943
Ensembl chr10:81,346,048...81,350,480
JBrowse link
G Hmgb2 high mobility group box 2 decreases expression ISO geraniol results in decreased expression of HMGB2 mRNA CTD PMID:27683099 NCBI chr 8:57,511,843...57,515,999
Ensembl chr 8:57,511,907...57,515,999
JBrowse link
G Hmgb3 high mobility group box 3 decreases expression ISO geraniol results in decreased expression of HMGB3 mRNA CTD PMID:27683099 NCBI chr  X:71,555,917...71,560,673
Ensembl chr  X:71,555,918...71,560,676
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase decreases expression
affects expression
decreases activity
increases expression
ISO
EXP
geraniol results in decreased expression of HMGCR protein
geraniol affects the expression of HMGCR mRNA
geraniol results in decreased activity of HMGCR protein
geraniol results in increased expression of HMGCR mRNA
CTD PMID:12477733 PMID:15450939 PMID:16462894 PMID:23668785 PMID:24875281 PMID:26141755 NCBI chr13:96,648,962...96,670,936
Ensembl chr13:96,648,967...96,670,936
JBrowse link
G Hmgxb3 HMG box domain containing 3 increases expression ISO geraniol results in increased expression of HMGXB3 mRNA CTD PMID:27683099 NCBI chr18:61,131,277...61,177,050
Ensembl chr18:61,131,277...61,177,050
JBrowse link
G Hmgxb4 HMG box domain containing 4 decreases expression ISO geraniol results in decreased expression of HMGXB4 mRNA CTD PMID:27683099 NCBI chr 8:74,993,650...75,031,978
Ensembl chr 8:74,993,356...75,031,978
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO geraniol results in increased expression of HMOX1 mRNA
geraniol results in increased expression of HMOX1 protein
CTD PMID:20713136 PMID:28334550 PMID:30806763 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Hnrnpab heterogeneous nuclear ribonucleoprotein A/B decreases expression ISO geraniol results in decreased expression of HNRNPAB mRNA CTD PMID:27683099 NCBI chr11:51,600,100...51,606,881
Ensembl chr11:51,600,100...51,606,847
JBrowse link
G Hoxa5 homeobox A5 increases expression ISO geraniol results in increased expression of HOXA5 mRNA CTD PMID:27683099 NCBI chr 6:52,201,754...52,204,587
Ensembl chr 6:52,201,754...52,204,587
JBrowse link
G Hoxb13 homeobox B13 decreases expression ISO geraniol results in decreased expression of HOXB13 mRNA CTD PMID:27683099 NCBI chr11:96,194,316...96,196,610
Ensembl chr11:96,194,316...96,197,447
JBrowse link
G Hoxc6 homeobox C6 increases expression ISO geraniol results in increased expression of HOXC6 mRNA CTD PMID:27683099 NCBI chr15:102,998,226...103,011,882
Ensembl chr15:102,998,257...103,011,881
JBrowse link
G Hras Harvey rat sarcoma virus oncogene multiple interactions EXP [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with geraniol] affects the localization of HRAS protein CTD PMID:22760862 NCBI chr 7:141,189,934...141,194,019
Ensembl chr 7:141,189,105...141,194,005
JBrowse link
G Hspa2 heat shock protein 2 decreases expression ISO geraniol results in decreased expression of HSPA2 mRNA CTD PMID:27683099 NCBI chr12:76,403,812...76,406,938
Ensembl chr12:76,404,176...76,406,938
JBrowse link
G Htr3a 5-hydroxytryptamine (serotonin) receptor 3A decreases activity ISO geraniol results in decreased activity of HTR3A protein CTD PMID:26456648 NCBI chr 9:48,899,213...48,911,152
Ensembl chr 9:48,899,213...48,911,099
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions EXP
ISO
geraniol inhibits the reaction [Dietary Fats results in increased expression of ICAM1 protein]
geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]
geraniol inhibits the reaction [Palmitic Acid results in increased expression of ICAM1 protein]
CTD PMID:26165751 PMID:27107694 NCBI chr 9:21,015,940...21,028,814
Ensembl chr 9:21,015,985...21,028,817
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression ISO geraniol results in increased expression of ID1 mRNA CTD PMID:27683099 NCBI chr 2:152,736,251...152,737,410
Ensembl chr 2:152,736,251...152,737,410
JBrowse link
G Id3 inhibitor of DNA binding 3 increases expression ISO geraniol results in increased expression of ID3 mRNA CTD PMID:27683099 NCBI chr 4:136,143,822...136,145,392
Ensembl chr 4:136,143,497...136,145,755
JBrowse link
G Ifng interferon gamma multiple interactions EXP geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IFNG protein] CTD PMID:26973525 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression
EXP
ISO
geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL10 protein]
geraniol results in increased expression of IL10 protein
CTD PMID:24934659 PMID:26973525 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974
JBrowse link
G Il16 interleukin 16 increases secretion ISO geraniol results in increased secretion of IL16 protein CTD PMID:30806763 NCBI chr 7:83,642,819...83,746,028
Ensembl chr 7:83,642,825...83,745,726
JBrowse link
G Il17a interleukin 17A multiple interactions EXP geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL17A protein] CTD PMID:26973525 NCBI chr 1:20,730,905...20,734,496
Ensembl chr 1:20,730,905...20,734,496
JBrowse link
G Il18 interleukin 18 multiple interactions EXP geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]; geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]]; geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]]; geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]] CTD PMID:21430599 NCBI chr 9:50,554,700...50,581,841
Ensembl chr 9:50,554,827...50,581,840
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO geraniol results in increased expression of IL1A protein CTD PMID:19878710 NCBI chr 2:129,299,609...129,310,186
Ensembl chr 2:129,299,610...129,309,972
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of IL1B protein]; geraniol inhibits the reaction [Fructose results in increased expression of IL1B protein]; geraniol inhibits the reaction [Fructose results in increased secretion of IL1B protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]
geraniol inhibits the reaction [[MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased expression of IL1B protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL1B protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]
2-chloro-5-nitrobenzanilide inhibits the reaction [geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of IL1B protein]]; geraniol inhibits the reaction [[Alendronate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]; geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of IL1B protein]; geraniol inhibits the reaction [[Pamidronate co-treated with Acetylmuramyl-Alanyl-Isoglutamine] results in increased secretion of IL1B protein]; geraniol inhibits the reaction [[Pamidronate co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]; geraniol inhibits the reaction [ovalbumin-alum results in increased expression of and results in increased secretion of IL1B protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]]; geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]]; geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]]
CTD PMID:20304105 PMID:21282739 PMID:21430599 PMID:23399806 PMID:25679220 PMID:26165751 PMID:26190278 PMID:26973525 PMID:28397014 PMID:29050341 PMID:30254419 PMID:30550845 PMID:31005848 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il1r2 interleukin 1 receptor, type II increases expression ISO geraniol results in increased expression of IL1R2 mRNA CTD PMID:30806763 NCBI chr 1:40,084,692...40,125,230
Ensembl chr 1:40,074,079...40,125,231
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO
EXP
geraniol results in increased expression of IL6 mRNA
geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL6 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]
geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; geraniol inhibits the reaction [Dietary Fats results in increased expression of IL6 protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]
geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 protein]; geraniol inhibits the reaction [Fructose results in increased expression of IL6 protein]
CTD PMID:23399806 PMID:26190278 PMID:26695085 PMID:26973525 PMID:27107694 PMID:28358702 PMID:29050341 PMID:30254419 PMID:31005848 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Il7r interleukin 7 receptor increases expression ISO geraniol results in increased expression of IL7R mRNA CTD PMID:20713136 NCBI chr15:9,506,159...9,529,941
Ensembl chr15:9,505,788...9,530,176
JBrowse link
G Ilf2 interleukin enhancer binding factor 2 decreases expression ISO geraniol results in decreased expression of ILF2 mRNA CTD PMID:27683099 NCBI chr 3:90,476,201...90,488,379
Ensembl chr 3:90,476,126...90,488,379
JBrowse link
G Ins1 insulin I increases secretion EXP geraniol results in increased secretion of INS1 protein CTD PMID:29070885 NCBI chr19:52,264,297...52,265,015
Ensembl chr19:52,264,297...52,265,476
JBrowse link
G Irf1 interferon regulatory factor 1 increases expression ISO geraniol results in increased expression of IRF1 mRNA CTD PMID:27683099 NCBI chr11:53,770,014...53,778,374
Ensembl chr11:53,770,014...53,778,374
JBrowse link
G Irf6 interferon regulatory factor 6 increases expression ISO geraniol results in increased expression of IRF6 mRNA CTD PMID:27683099 NCBI chr 1:193,153,112...193,172,036
Ensembl chr 1:193,153,111...193,172,023
JBrowse link
G Irf7 interferon regulatory factor 7 increases expression ISO geraniol results in increased expression of IRF7 mRNA CTD PMID:27683099 NCBI chr 7:141,263,183...141,266,499
Ensembl chr 7:141,262,706...141,266,481
JBrowse link
G Irf9 interferon regulatory factor 9 increases expression ISO geraniol results in increased expression of IRF9 mRNA CTD PMID:27683099 NCBI chr14:55,603,985...55,610,030
Ensembl chr14:55,603,571...55,610,030
JBrowse link
G Jarid2 jumonji, AT rich interactive domain 2 increases expression ISO geraniol results in increased expression of JARID2 mRNA CTD PMID:27683099 NCBI chr13:44,730,774...44,921,643
Ensembl chr13:44,729,474...44,921,643
JBrowse link
G Jmjd1c jumonji domain containing 1C increases expression ISO geraniol results in increased expression of JMJD1C mRNA CTD PMID:27683099 NCBI chr10:67,096,351...67,256,326
Ensembl chr10:67,096,125...67,256,326
JBrowse link
G Jun jun proto-oncogene increases expression ISO geraniol results in increased expression of JUN mRNA CTD PMID:27683099 NCBI chr 4:95,049,036...95,052,222
Ensembl chr 4:95,049,034...95,052,222
JBrowse link
G Junb jun B proto-oncogene increases expression ISO geraniol results in increased expression of JUNB mRNA CTD PMID:27683099 NCBI chr 8:84,976,909...84,978,748
Ensembl chr 8:84,974,484...84,978,718
Ensembl chr 8:84,974,484...84,978,718
JBrowse link
G Jund jun D proto-oncogene increases expression ISO geraniol results in increased expression of JUND mRNA CTD PMID:27683099 NCBI chr 8:70,697,739...70,700,616
Ensembl chr 8:70,698,949...70,700,616
JBrowse link
G Kdr kinase insert domain protein receptor decreases expression EXP geraniol results in decreased expression of KDR protein CTD PMID:26154255 NCBI chr 5:75,932,827...75,979,072
Ensembl chr 5:75,932,827...75,978,458
JBrowse link
G Khdrbs1 KH domain containing, RNA binding, signal transduction associated 1 decreases expression ISO geraniol results in decreased expression of KHDRBS1 mRNA CTD PMID:27683099 NCBI chr 4:129,702,380...129,743,878
Ensembl chr 4:129,703,164...129,742,303
JBrowse link
G Kif11 kinesin family member 11 decreases expression ISO geraniol results in decreased expression of KIF11 mRNA CTD PMID:27683099 NCBI chr19:37,376,382...37,421,863
Ensembl chr19:37,376,403...37,421,859
JBrowse link
G Kif15 kinesin family member 15 decreases expression ISO geraniol results in decreased expression of KIF15 mRNA CTD PMID:27683099 NCBI chr 9:122,951,081...123,018,733
Ensembl chr 9:122,951,046...123,018,733
JBrowse link
G Kif22 kinesin family member 22 decreases expression ISO geraniol results in decreased expression of KIF22 mRNA CTD PMID:27683099 NCBI chr 7:127,027,729...127,042,467
Ensembl chr 7:127,027,729...127,042,471
JBrowse link
G Kif23 kinesin family member 23 decreases expression ISO geraniol results in decreased expression of KIF23 mRNA CTD PMID:27683099 NCBI chr 9:61,917,277...61,946,810
Ensembl chr 9:61,915,905...61,946,774
JBrowse link
G Kif2c kinesin family member 2C decreases expression ISO geraniol results in decreased expression of KIF2C mRNA CTD PMID:27683099 NCBI chr 4:117,159,633...117,182,624
Ensembl chr 4:117,159,639...117,182,639
JBrowse link
G Klf11 Kruppel-like factor 11 increases expression ISO geraniol results in increased expression of KLF11 mRNA CTD PMID:27683099 NCBI chr12:24,651,371...24,662,782
Ensembl chr12:24,651,274...24,662,789
JBrowse link
G Klf13 Kruppel-like factor 13 increases expression ISO geraniol results in increased expression of KLF13 mRNA CTD PMID:27683099 NCBI chr 7:63,886,351...63,938,915
Ensembl chr 7:63,886,351...63,938,915
JBrowse link
G Klf3 Kruppel-like factor 3 (basic) increases expression ISO geraniol results in increased expression of KLF3 mRNA CTD PMID:27683099 NCBI chr 5:64,803,521...64,832,901
Ensembl chr 5:64,803,388...64,832,901
JBrowse link
G Klf4 Kruppel-like factor 4 (gut) increases expression ISO geraniol results in increased expression of KLF4 mRNA CTD PMID:27683099 NCBI chr 4:55,527,137...55,532,475
Ensembl chr 4:55,527,143...55,532,466
JBrowse link
G Klf5 Kruppel-like factor 5 increases expression ISO geraniol results in increased expression of KLF5 mRNA CTD PMID:27683099 NCBI chr14:99,298,691...99,313,412
Ensembl chr14:99,298,691...99,315,036
JBrowse link
G Klf6 Kruppel-like factor 6 increases expression ISO geraniol results in increased expression of KLF6 mRNA CTD PMID:27683099 NCBI chr13:5,861,489...5,870,393
Ensembl chr13:5,861,482...5,870,394
JBrowse link
G Klf7 Kruppel-like factor 7 (ubiquitous) increases expression ISO geraniol results in increased expression of KLF7 mRNA CTD PMID:27683099 NCBI chr 1:64,029,448...64,122,345
Ensembl chr 1:64,029,447...64,122,282
JBrowse link
G Kntc1 kinetochore associated 1 decreases expression ISO geraniol results in decreased expression of KNTC1 mRNA CTD PMID:27683099 NCBI chr 5:123,749,692...123,821,593
Ensembl chr 5:123,749,716...123,821,593
JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog multiple interactions ISO geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of KRAS mRNA] CTD PMID:28428697 NCBI chr 6:145,216,699...145,250,420
Ensembl chr 6:145,216,699...145,250,239
JBrowse link
G Ldlr low density lipoprotein receptor increases expression EXP geraniol results in increased expression of LDLR mRNA CTD PMID:26141755 NCBI chr 9:21,723,576...21,749,919
Ensembl chr 9:21,723,483...21,749,919
JBrowse link
G Lif leukemia inhibitory factor decreases expression ISO geraniol results in decreased expression of LIF protein CTD PMID:19878710 NCBI chr11:4,257,568...4,272,514
Ensembl chr11:4,257,557...4,272,514
JBrowse link
G Lztfl1 leucine zipper transcription factor-like 1 increases expression ISO geraniol results in increased expression of LZTFL1 mRNA CTD PMID:27683099 NCBI chr 9:123,694,404...123,717,625
Ensembl chr 9:123,694,416...123,717,697
JBrowse link
G Lztr1 leucine-zipper-like transcriptional regulator, 1 increases expression ISO geraniol results in increased expression of LZTR1 mRNA CTD PMID:27683099 NCBI chr16:17,508,260...17,526,333
Ensembl chr16:17,508,688...17,526,333
JBrowse link
G Mad2l1 MAD2 mitotic arrest deficient-like 1 decreases expression ISO geraniol results in decreased expression of MAD2L1 mRNA CTD PMID:27683099 NCBI chr 6:66,535,221...66,541,107
Ensembl chr 6:66,535,390...66,547,220
JBrowse link
G Maff v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) increases expression ISO geraniol results in increased expression of MAFF mRNA CTD PMID:27683099 NCBI chr15:79,346,621...79,359,078
Ensembl chr15:79,346,621...79,359,076
JBrowse link
G Mafg v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian) increases expression ISO geraniol results in increased expression of MAFG mRNA CTD PMID:27683099 NCBI chr11:120,625,117...120,634,955
Ensembl chr11:120,625,117...120,633,600
JBrowse link
G Maob monoamine oxidase B multiple interactions EXP geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of MAOB protein] CTD PMID:24103762 NCBI chr  X:16,709,281...16,817,366
Ensembl chr  X:16,709,282...16,817,366
JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 multiple interactions ISO geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of MAP2K1 mRNA] CTD PMID:28428697 NCBI chr 9:64,185,769...64,253,605
Ensembl chr 9:64,185,770...64,253,631
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
decreases phosphorylation
EXP
ISO
geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK1 protein]
geraniol results in decreased phosphorylation of MAPK1 protein
CTD PMID:12388655 PMID:22760862 PMID:26154255 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
decreases phosphorylation
EXP
ISO
geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK3 protein]
geraniol results in decreased phosphorylation of MAPK3 protein
CTD PMID:12388655 PMID:22760862 PMID:26154255 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 decreases expression ISO geraniol results in decreased expression of MCM2 mRNA CTD PMID:27683099 NCBI chr 6:88,883,474...88,898,780
Ensembl chr 6:88,883,474...88,898,780
JBrowse link
G Mef2a myocyte enhancer factor 2A increases expression ISO geraniol results in increased expression of MEF2A mRNA CTD PMID:27683099 NCBI chr 7:67,231,163...67,376,456
Ensembl chr 7:67,231,163...67,372,858
JBrowse link
G Men1 multiple endocrine neoplasia 1 increases expression ISO geraniol results in increased expression of MEN1 mRNA CTD PMID:27683099 NCBI chr19:6,334,979...6,340,894
Ensembl chr19:6,334,979...6,340,891
JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 decreases expression ISO
EXP
geraniol results in decreased expression of MKI67 mRNA
geraniol results in decreased expression of MKI67 protein
CTD PMID:26154255 PMID:27683099 NCBI chr 7:135,689,784...135,716,450
Ensembl chr 7:135,689,784...135,716,361
JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression ISO geraniol results in increased expression of MMP3 mRNA CTD PMID:30806763 NCBI chr 9:7,445,822...7,455,975
Ensembl chr 9:7,445,822...7,455,975
JBrowse link
G Mnt max binding protein increases expression ISO geraniol results in increased expression of MNT mRNA CTD PMID:27683099 NCBI chr11:74,830,806...74,845,725
Ensembl chr11:74,830,920...74,845,725
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP
ISO
2-chloro-5-nitrobenzanilide inhibits the reaction [geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased activity of MPO protein]]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased activity of MPO protein]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of MPO protein]
geraniol inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of MPO protein]; geraniol inhibits the reaction [Cysteamine results in increased expression of MPO protein]; geraniol inhibits the reaction [Ethanol results in increased expression of MPO protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]
CTD PMID:24337826 PMID:26165751 PMID:26190278 PMID:30550845 NCBI chr11:87,793,784...87,804,412
Ensembl chr11:87,793,581...87,804,413
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases activity
multiple interactions
ISO geraniol results in decreased activity of MTOR protein
geraniol inhibits the reaction [Rotenone results in increased phosphorylation of MTOR protein]
CTD PMID:22200837 PMID:30141137 NCBI chr 4:148,448,582...148,557,685
Ensembl chr 4:148,448,611...148,557,683
JBrowse link
G Mvk mevalonate kinase multiple interactions ISO geraniol inhibits the reaction [[MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased expression of IL1B protein]; geraniol inhibits the reaction [MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] CTD PMID:20304105 NCBI chr 5:114,444,264...114,460,591
Ensembl chr 5:114,444,269...114,460,591
JBrowse link
G Mxd1 MAX dimerization protein 1 increases expression ISO geraniol results in increased expression of MXD1 mRNA CTD PMID:27683099 NCBI chr 6:86,647,044...86,669,234
Ensembl chr 6:86,647,042...86,669,161
JBrowse link
G Mxd4 Max dimerization protein 4 increases expression ISO geraniol results in increased expression of MXD4 mRNA CTD PMID:27683099 NCBI chr 5:34,176,580...34,187,710
Ensembl chr 5:34,173,883...34,187,720
JBrowse link
G Mxi1 MAX interactor 1, dimerization protein increases expression ISO geraniol results in increased expression of MXI1 mRNA CTD PMID:27683099 NCBI chr19:53,310,128...53,373,293
Ensembl chr19:53,310,518...53,375,810
JBrowse link
G Myb myeloblastosis oncogene decreases expression ISO geraniol results in decreased expression of MYB mRNA CTD PMID:27683099 NCBI chr10:21,124,930...21,160,984
Ensembl chr10:21,124,935...21,160,984
JBrowse link
G Mybl1 myeloblastosis oncogene-like 1 decreases expression ISO geraniol results in decreased expression of MYBL1 mRNA CTD PMID:27683099 NCBI chr 1:9,667,407...9,700,439
Ensembl chr 1:9,667,415...9,700,209
JBrowse link
G Mybl2 myeloblastosis oncogene-like 2 decreases expression ISO geraniol results in decreased expression of MYBL2 mRNA CTD PMID:27683099 NCBI chr 2:163,054,327...163,084,688
Ensembl chr 2:163,054,687...163,084,688
JBrowse link
G Myo6 myosin VI increases expression ISO geraniol results in increased expression of MYO6 mRNA CTD PMID:27683099 NCBI chr 9:80,164,976...80,311,729
Ensembl chr 9:80,165,031...80,311,729
JBrowse link
G Nasp nuclear autoantigenic sperm protein (histone-binding) decreases expression ISO geraniol results in decreased expression of NASP mRNA CTD PMID:27683099 NCBI chr 4:116,601,052...116,628,676
Ensembl chr 4:116,601,052...116,627,941
JBrowse link
G Ncaph non-SMC condensin I complex, subunit H decreases expression ISO geraniol results in decreased expression of NCAPH mRNA CTD PMID:27683099 NCBI chr 2:127,103,809...127,133,954
Ensembl chr 2:127,103,809...127,133,954
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 increases expression ISO geraniol results in increased expression of NCOR1 mRNA CTD PMID:27683099 NCBI chr11:62,315,663...62,457,414
Ensembl chr11:62,316,426...62,458,541
JBrowse link
G Ndp Norrie disease (pseudoglioma) (human) decreases expression ISO geraniol results in decreased expression of NDP mRNA CTD PMID:27683099 NCBI chr  X:16,885,521...16,911,774
Ensembl chr  X:16,885,521...16,911,774
JBrowse link
G Nek2 NIMA (never in mitosis gene a)-related expressed kinase 2 decreases expression ISO geraniol results in decreased expression of NEK2 mRNA CTD PMID:27683099 NCBI chr 1:191,821,449...191,833,049
Ensembl chr 1:191,821,444...191,833,050
JBrowse link
G Nfat5 nuclear factor of activated T cells 5 increases expression ISO geraniol results in increased expression of NFAT5 mRNA CTD PMID:27683099 NCBI chr 8:107,293,435...107,379,517
Ensembl chr 8:107,293,470...107,379,517
JBrowse link
G Nfe2l1 nuclear factor, erythroid derived 2,-like 1 increases expression ISO geraniol results in increased expression of NFE2L1 mRNA CTD PMID:27683099 NCBI chr11:96,817,414...96,829,968
Ensembl chr11:96,817,414...96,829,968
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 increases expression ISO geraniol results in increased expression of NFE2L2 mRNA
geraniol results in increased expression of NFE2L2 protein
CTD PMID:27683099 PMID:28334550 NCBI chr 2:75,675,513...75,704,663
Ensembl chr 2:75,675,513...75,704,641
JBrowse link
G Nfil3 nuclear factor, interleukin 3, regulated increases expression ISO geraniol results in increased expression of NFIL3 mRNA CTD PMID:27683099 NCBI chr13:52,967,209...52,982,878
Ensembl chr13:52,967,209...52,981,073
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions ISO geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of NFKB1 mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NFKB1 protein] CTD PMID:21907755 PMID:26165751 NCBI chr 3:135,584,655...135,691,969
Ensembl chr 3:135,584,655...135,691,547
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions EXP geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of NFKBIA mRNA]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of NFKBIA protein modified form]; geraniol inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKBIA protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NFKBIA protein modified form]; geraniol inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:20506077 PMID:26190278 PMID:29050341 PMID:30550845 NCBI chr12:55,489,409...55,492,647
Ensembl chr12:55,489,410...55,492,647
JBrowse link
G Nfyb nuclear transcription factor-Y beta decreases expression ISO geraniol results in decreased expression of NFYB mRNA CTD PMID:27683099 NCBI chr10:82,748,700...82,764,151
Ensembl chr10:82,748,701...82,764,144
JBrowse link
G Nos2 nitric oxide synthase 2, inducible decreases expression
multiple interactions
EXP
ISO
geraniol results in decreased expression of NOS2 mRNA; geraniol results in decreased expression of NOS2 protein
geraniol inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 protein]
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased expression of NOS2 mRNA]; [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased expression of NOS2 protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of NOS2 protein]; geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of NOS2 protein]; geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of NOS2 protein]
CTD PMID:20506077 PMID:22509279 PMID:26190278 PMID:26364502 PMID:26695085 PMID:28397014 PMID:29050341 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254
JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions ISO geraniol inhibits the reaction [Palmitic Acid results in increased expression of NOX1 protein] CTD PMID:27107694 NCBI chr  X:134,086,421...134,137,711
Ensembl chr  X:134,086,421...134,221,956
JBrowse link
G Npm1 nucleophosmin 1 decreases expression ISO geraniol results in decreased expression of NPM1 mRNA CTD PMID:27683099 NCBI chr11:33,152,498...33,164,142
Ensembl chr11:33,152,287...33,163,206
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions ISO geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in decreased activity of NQO1 protein] CTD PMID:23499697 NCBI chr 8:107,388,225...107,403,205
Ensembl chr 8:107,388,225...107,403,206
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 increases expression ISO geraniol results in increased expression of NR1D1 mRNA CTD PMID:27683099 NCBI chr11:98,767,932...98,775,377
Ensembl chr11:98,767,932...98,775,333
JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 increases expression ISO geraniol results in increased expression of NR1D2 mRNA CTD PMID:27683099 NCBI chr14:18,204,056...18,239,106
Ensembl chr14:18,204,054...18,239,127
JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 decreases expression ISO geraniol results in decreased expression of NR2F1 mRNA CTD PMID:27683099 NCBI chr13:78,188,971...78,198,873
Ensembl chr13:78,188,973...78,199,757
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases expression ISO geraniol results in increased expression of NR3C1 mRNA CTD PMID:27683099 NCBI chr18:39,410,545...39,519,421
Ensembl chr18:39,410,545...39,519,421
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases expression ISO geraniol results in increased expression of NR4A2 mRNA CTD PMID:27683099 NCBI chr 2:57,106,830...57,124,003
Ensembl chr 2:57,106,830...57,124,003
JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 decreases expression ISO geraniol results in decreased expression of NSD2 mRNA CTD PMID:27683099 NCBI chr 5:33,820,676...33,897,966
Ensembl chr 5:33,820,725...33,897,975
JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 decreases expression ISO geraniol results in decreased expression of NUSAP1 mRNA CTD PMID:27683099 NCBI chr 2:119,618,298...119,650,165
Ensembl chr 2:119,618,298...119,651,244
JBrowse link
G Odc1 ornithine decarboxylase, structural 1 multiple interactions
decreases activity
EXP
ISO
geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 protein]
geraniol results in decreased activity of ODC1 protein
CTD PMID:11408542 PMID:22760862 NCBI chr12:17,544,808...17,551,502
Ensembl chr12:17,544,794...17,551,505
JBrowse link
G Ogg1 8-oxoguanine DNA-glycosylase 1 multiple interactions ISO [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased expression of OGG1 protein] CTD PMID:22509279 NCBI chr 6:113,326,972...113,334,877
Ensembl chr 6:113,326,972...113,335,068
JBrowse link
G Olfr43 olfactory receptor 43 multiple interactions ISO [GNA15 protein results in increased susceptibility to geraniol] which results in increased activity of OLFR43 protein; [GNAL protein results in increased susceptibility to geraniol] which results in increased activity of OLFR43 protein; OR1A1 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein] CTD PMID:15598656 PMID:29070885 NCBI chr11:74,206,198...74,207,289
Ensembl chr11:74,205,664...74,211,379
JBrowse link
G Pa2g4 proliferation-associated 2G4 decreases expression ISO geraniol results in decreased expression of PA2G4 mRNA CTD PMID:27683099 NCBI chr10:128,557,766...128,565,934
Ensembl chr10:128,557,766...128,565,987
JBrowse link
G Pbx1 pre B cell leukemia homeobox 1 decreases expression ISO geraniol results in decreased expression of PBX1 mRNA CTD PMID:27683099 NCBI chr 1:168,119,364...168,432,365
Ensembl chr 1:168,119,364...168,432,270
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions
decreases expression
ISO
EXP
geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of PCNA protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of PCNA mRNA]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of PCNA protein]; geraniol inhibits the reaction [Diethylnitrosamine results in increased expression of PCNA protein]; geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA protein]
geraniol results in decreased expression of PCNA protein
CTD PMID:21907755 PMID:26154255 PMID:26364502 PMID:27046949 PMID:28428697 NCBI chr 2:132,249,286...132,253,180
Ensembl chr 2:132,249,162...132,253,314
JBrowse link
G Pgr progesterone receptor multiple interactions ISO geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of PGR protein] CTD PMID:28428697 NCBI chr 9:8,898,900...8,968,611
Ensembl chr 9:8,899,833...8,968,611
JBrowse link
G Phb prohibitin decreases expression
multiple interactions
ISO geraniol results in decreased expression of PHB mRNA
geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PHB protein]
CTD PMID:26695085 PMID:27683099 NCBI chr11:95,666,957...95,680,773
Ensembl chr11:95,666,957...95,680,773
JBrowse link
G Phf1 PHD finger protein 1 increases expression ISO geraniol results in increased expression of PHF1 mRNA CTD PMID:27683099 NCBI chr17:26,933,127...26,937,908
Ensembl chr17:26,933,052...26,937,908
JBrowse link
G Phf21a PHD finger protein 21A increases expression ISO geraniol results in increased expression of PHF21A mRNA CTD PMID:27683099 NCBI chr 2:92,183,751...92,364,667
Ensembl chr 2:92,093,117...92,364,666
JBrowse link
G Phtf1 putative homeodomain transcription factor 1 increases expression ISO geraniol results in increased expression of PHTF1 mRNA CTD PMID:27683099 NCBI chr 3:103,968,110...104,007,490
Ensembl chr 3:103,968,110...104,024,598
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions ISO geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PIK3R1 mRNA] CTD PMID:28428697 NCBI chr13:101,680,761...101,768,217
Ensembl chr13:101,680,563...101,768,217
JBrowse link
G Pkmyt1 protein kinase, membrane associated tyrosine/threonine 1 decreases expression ISO geraniol results in decreased expression of PKMYT1 mRNA CTD PMID:27683099 NCBI chr17:23,726,336...23,736,735
Ensembl chr17:23,726,336...23,736,735
JBrowse link
G Plagl1 pleiomorphic adenoma gene-like 1 increases expression ISO geraniol results in increased expression of PLAGL1 mRNA CTD PMID:27683099 NCBI chr10:13,090,832...13,131,694
Ensembl chr10:13,060,504...13,131,694
JBrowse link
G Plk1 polo like kinase 1 decreases expression ISO geraniol results in decreased expression of PLK1 mRNA CTD PMID:27683099 NCBI chr 7:122,159,435...122,169,884
Ensembl chr 7:122,159,439...122,169,873
JBrowse link
G Pola1 polymerase (DNA directed), alpha 1 decreases expression ISO geraniol results in decreased expression of POLA1 mRNA CTD PMID:27683099 NCBI chr  X:93,304,766...93,632,387
Ensembl chr  X:93,304,767...93,632,155
JBrowse link
G Pole polymerase (DNA directed), epsilon decreases expression ISO geraniol results in decreased expression of POLE mRNA CTD PMID:27683099 NCBI chr 5:110,286,319...110,337,468
Ensembl chr 5:110,286,306...110,337,474
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions ISO geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased activity of POR protein] CTD PMID:23499697 NCBI chr 5:135,670,040...135,735,326
Ensembl chr 5:135,670,033...135,735,326
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
increases activity
ISO geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PPARA mRNA]
geraniol results in increased activity of PPARA protein
CTD PMID:21597168 PMID:26695085 NCBI chr15:85,734,910...85,806,851
Ensembl chr15:85,734,983...85,802,819
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma decreases expression
increases activity
multiple interactions
ISO
EXP
geraniol results in decreased expression of PPARG mRNA
geraniol results in increased activity of PPARG protein
geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in decreased expression of PPARG mRNA]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in decreased expression of PPARG protein]
geraniol inhibits the reaction [Fructose results in decreased activity of PPARG protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]
CTD PMID:21597168 PMID:25679220 PMID:26165751 PMID:27683099 PMID:30550845 NCBI chr 6:115,360,879...115,490,404
Ensembl chr 6:115,360,951...115,490,399
JBrowse link
G Prc1 protein regulator of cytokinesis 1 decreases expression ISO geraniol results in decreased expression of PRC1 mRNA CTD PMID:27683099 NCBI chr 7:80,294,445...80,316,259
Ensembl chr 7:80,294,450...80,316,259
JBrowse link
G Prdm4 PR domain containing 4 increases expression ISO geraniol results in increased expression of PRDM4 mRNA CTD PMID:27683099 NCBI chr10:85,891,964...85,917,152
Ensembl chr10:85,891,966...85,917,142
JBrowse link
G Prdx3 peroxiredoxin 3 decreases expression ISO geraniol results in decreased expression of PRDX3 mRNA CTD PMID:27683099 NCBI chr19:60,864,066...60,874,538
Ensembl chr19:60,864,051...60,874,556
JBrowse link
G Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit multiple interactions ISO geraniol inhibits the reaction [Rotenone results in increased expression of PRKAA1 protein] CTD PMID:30141137 NCBI chr15:5,143,861...5,181,899
Ensembl chr15:5,143,861...5,181,899
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of PTEN protein] CTD PMID:28428697 NCBI chr19:32,757,577...32,826,160
Ensembl chr19:32,757,497...32,826,160
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP
ISO
geraniol inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 mRNA]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; geraniol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of PTGS2 protein]
CTD PMID:20506077 PMID:21597168 PMID:22760862 PMID:23399806 PMID:26190278 PMID:26364502 PMID:26973525 PMID:28397014 PMID:29050341 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Pttg1 pituitary tumor-transforming gene 1 decreases expression ISO geraniol results in decreased expression of PTTG1 mRNA CTD PMID:27683099 NCBI chr11:43,420,244...43,427,463
Ensembl chr11:43,420,250...43,426,251
JBrowse link
G Pwp1 PWP1 homolog, endonuclein decreases expression ISO geraniol results in decreased expression of PWP1 mRNA CTD PMID:27683099 NCBI chr10:85,871,831...85,889,103
Ensembl chr10:85,829,494...85,889,096
JBrowse link
G Racgap1 Rac GTPase-activating protein 1 decreases expression ISO geraniol results in decreased expression of RACGAP1 mRNA CTD PMID:27683099 NCBI chr15:99,620,496...99,651,656
Ensembl chr15:99,620,496...99,651,656
JBrowse link
G Rad51 RAD51 recombinase decreases expression ISO geraniol results in decreased expression of RAD51 mRNA CTD PMID:27683099 NCBI chr 2:119,112,814...119,136,073
Ensembl chr 2:119,112,793...119,147,445
JBrowse link
G Rad54b RAD54 homolog B (S. cerevisiae) decreases expression ISO geraniol results in decreased expression of RAD54B mRNA CTD PMID:27683099 NCBI chr 4:11,558,920...11,615,808
Ensembl chr 4:11,558,922...11,615,805
JBrowse link
G Rad54l RAD54 like (S. cerevisiae) decreases expression ISO geraniol results in decreased expression of RAD54L mRNA CTD PMID:27683099 NCBI chr 4:116,094,261...116,123,700
Ensembl chr 4:116,094,264...116,123,690
JBrowse link
G Raf1 v-raf-leukemia viral oncogene 1 multiple interactions EXP geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RAF1 protein] CTD PMID:22760862 NCBI chr 6:115,618,569...115,676,635
Ensembl chr 6:115,618,067...115,676,635
JBrowse link
G Rcan1 regulator of calcineurin 1 increases expression ISO geraniol results in increased expression of RCAN1 mRNA CTD PMID:27683099 NCBI chr16:92,391,951...92,466,169
Ensembl chr16:92,391,953...92,470,867
JBrowse link
G Rcor3 REST corepressor 3 increases expression ISO geraniol results in increased expression of RCOR3 mRNA CTD PMID:27683099 NCBI chr 1:192,098,546...192,138,074
Ensembl chr 1:192,098,546...192,138,062
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO
EXP
geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of RELA protein]; geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of and affects the localization of RELA protein]
geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of RELA mRNA]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of RELA protein modified form]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of and affects the localization of and results in increased activity of RELA protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of RELA protein modified form]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]
CTD PMID:23399806 PMID:26190278 PMID:26364502 PMID:28397014 PMID:29050341 PMID:30550845 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130
JBrowse link
G Rfx5 regulatory factor X, 5 (influences HLA class II expression) increases expression ISO geraniol results in increased expression of RFX5 mRNA CTD PMID:27683099 NCBI chr 3:94,950,689...94,961,561
Ensembl chr 3:94,954,075...94,961,561
JBrowse link
G Rnf19a ring finger protein 19A increases expression ISO geraniol results in increased expression of RNF19A mRNA CTD PMID:27683099 NCBI chr15:36,239,934...36,283,147
Ensembl chr15:36,239,933...36,283,147
JBrowse link
G Ruvbl1 RuvB-like protein 1 decreases expression ISO geraniol results in decreased expression of RUVBL1 mRNA CTD PMID:27683099 NCBI chr 6:88,465,409...88,497,566
Ensembl chr 6:88,465,409...88,497,572
JBrowse link
G Ruvbl2 RuvB-like protein 2 decreases expression ISO geraniol results in decreased expression of RUVBL2 mRNA CTD PMID:27683099 NCBI chr 7:45,421,896...45,436,171
Ensembl chr 7:45,421,760...45,438,096
JBrowse link
G Satb1 special AT-rich sequence binding protein 1 increases expression ISO geraniol results in increased expression of SATB1 mRNA CTD PMID:27683099 NCBI chr17:51,736,187...51,833,290
Ensembl chr17:51,736,187...51,833,290
JBrowse link
G Serpinb3d serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3D increases expression ISO geraniol results in increased expression of SERPINB3 mRNA CTD PMID:30806763 NCBI chr 1:107,078,163...107,083,480
Ensembl chr 1:107,078,167...107,083,506
JBrowse link
G Sim2 single-minded family bHLH transcription factor 2 increases expression ISO geraniol results in increased expression of SIM2 mRNA CTD PMID:27683099 NCBI chr16:94,085,104...94,127,032
Ensembl chr16:94,084,931...94,127,032
JBrowse link
G Sirt1 sirtuin 1 increases expression ISO geraniol results in increased expression of SIRT1 mRNA CTD PMID:27683099 NCBI chr10:63,319,005...63,339,035
Ensembl chr10:63,319,005...63,381,704
JBrowse link
G Skp2 S-phase kinase-associated protein 2 decreases expression ISO geraniol results in decreased expression of SKP2 mRNA CTD PMID:27683099 NCBI chr15:9,111,982...9,155,425
Ensembl chr15:9,111,985...9,155,425
JBrowse link
G Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 multiple interactions EXP geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SLC18A2 protein] CTD PMID:23943375 NCBI chr19:59,260,878...59,296,012
Ensembl chr19:59,260,896...59,296,012
JBrowse link
G Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 multiple interactions EXP geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SLC6A3 protein] CTD PMID:23943375 NCBI chr13:73,536,128...73,578,672
Ensembl chr13:73,536,747...73,578,672
JBrowse link
G Smad3 SMAD family member 3 decreases expression ISO geraniol results in decreased expression of SMAD3 mRNA CTD PMID:27683099 NCBI chr 9:63,646,766...63,757,994
Ensembl chr 9:63,646,767...63,757,994
JBrowse link
G Smad6 SMAD family member 6 decreases expression ISO geraniol results in decreased expression of SMAD6 mRNA CTD PMID:27683099 NCBI chr 9:63,953,076...64,022,085
Ensembl chr 9:63,953,076...64,022,059
JBrowse link
G Smad7 SMAD family member 7 increases expression ISO geraniol results in increased expression of SMAD7 mRNA CTD PMID:27683099 NCBI chr18:75,367,365...75,395,935
Ensembl chr18:75,367,529...75,395,935
JBrowse link
G Smarca2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 decreases expression ISO geraniol results in decreased expression of SMARCA2 mRNA CTD PMID:27683099 NCBI chr19:26,605,073...26,778,321
Ensembl chr19:26,605,050...26,778,322
JBrowse link
G Smarcal1 SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 increases expression ISO geraniol results in increased expression of SMARCAL1 mRNA CTD PMID:27683099 NCBI chr 1:72,536,695...72,636,790
Ensembl chr 1:72,583,251...72,633,134
JBrowse link
G Smc4 structural maintenance of chromosomes 4 decreases expression ISO geraniol results in decreased expression of SMC4 mRNA CTD PMID:27683099 NCBI chr 3:69,004,738...69,034,623
Ensembl chr 3:69,004,738...69,034,623
JBrowse link
G Snca synuclein, alpha multiple interactions ISO
EXP
geraniol inhibits the reaction [Rotenone results in increased expression of SNCA protein]; geraniol inhibits the reaction [SNCA protein results in decreased abundance of Dopamine]; geraniol inhibits the reaction [SNCA protein results in decreased abundance of Glutathione]; geraniol inhibits the reaction [SNCA protein results in increased abundance of Thiobarbituric Acid Reactive Substances]
geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SNCA mRNA]; geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SNCA protein]
CTD PMID:24103762 PMID:27026137 PMID:30141137 NCBI chr 6:60,731,573...60,829,855
Ensembl chr 6:60,731,575...60,829,855
JBrowse link
G Sod1 superoxide dismutase 1, soluble multiple interactions ISO [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of SOD1 mRNA]
geraniol inhibits the reaction [Rotenone results in decreased activity of SOD1 protein]
CTD PMID:22509279 PMID:30141137 NCBI chr16:90,220,762...90,226,333
Ensembl chr16:90,220,754...90,226,329
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial multiple interactions ISO [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of SOD2 mRNA]; [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of SOD2 protein]
geraniol inhibits the reaction [Rotenone results in decreased activity of SOD2 protein]
CTD PMID:22509279 PMID:30141137 NCBI chr17:13,007,839...13,018,119
Ensembl chr17:13,006,846...13,040,063
JBrowse link
G Sox9 SRY (sex determining region Y)-box 9 decreases expression ISO geraniol results in decreased expression of SOX9 mRNA CTD PMID:27683099 NCBI chr11:112,782,210...112,787,757
Ensembl chr11:112,782,224...112,787,760
JBrowse link
G Sp100 nuclear antigen Sp100 increases expression ISO geraniol results in increased expression of SP100 mRNA CTD PMID:27683099 NCBI chr 1:85,649,948...85,709,998
Ensembl chr 1:85,649,988...85,709,998
JBrowse link
G Sp140 Sp140 nuclear body protein increases expression ISO geraniol results in increased expression of SP140L mRNA CTD PMID:27683099 NCBI chr 1:85,587,491...85,645,040
Ensembl chr 1:85,600,378...85,645,037
JBrowse link
G Sqstm1 sequestosome 1 increases expression
multiple interactions
ISO geraniol results in increased expression of SQSTM1 mRNA
geraniol inhibits the reaction [Rotenone results in decreased expression of SQSTM1 protein]
CTD PMID:27683099 PMID:30141137 NCBI chr11:50,200,152...50,210,820
Ensembl chr11:50,199,366...50,210,827
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO geraniol promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of SREBF1 mRNA] CTD PMID:26695085 NCBI chr11:60,199,084...60,224,186
Ensembl chr11:60,199,089...60,222,581
JBrowse link
G Srebf2 sterol regulatory element binding factor 2 increases expression ISO geraniol results in increased expression of SREBF2 mRNA CTD PMID:23668785 NCBI chr15:82,147,269...82,205,379
Ensembl chr15:82,147,181...82,205,379
JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression ISO geraniol results in increased expression of STAT1 mRNA CTD PMID:27683099 NCBI chr 1:52,119,438...52,161,865
Ensembl chr 1:52,119,440...52,161,865
JBrowse link
G Stat2 signal transducer and activator of transcription 2 increases expression ISO geraniol results in increased expression of STAT2 mRNA CTD PMID:27683099 NCBI chr10:128,270,498...128,292,853
Ensembl chr10:128,270,559...128,292,849
JBrowse link
G Stat6 signal transducer and activator of transcription 6 increases expression ISO geraniol results in increased expression of STAT6 mRNA CTD PMID:27683099 NCBI chr10:127,642,955...127,660,987
Ensembl chr10:127,642,986...127,660,957
JBrowse link
G Stmn1 stathmin 1 decreases expression ISO geraniol results in decreased expression of STMN1 mRNA CTD PMID:27683099 NCBI chr 4:134,468,320...134,473,843
Ensembl chr 4:134,468,320...134,473,843
JBrowse link
G Sub1 SUB1 homolog, transcriptional regulator decreases expression ISO geraniol results in decreased expression of SUB1 mRNA CTD PMID:27683099 NCBI chr15:11,981,336...11,996,038
Ensembl chr15:11,981,339...11,996,983
JBrowse link
G Supt16 SPT16, facilitates chromatin remodeling subunit decreases expression ISO geraniol results in decreased expression of SUPT16H mRNA CTD PMID:27683099 NCBI chr14:52,160,419...52,197,239
Ensembl chr14:52,160,414...52,197,416
JBrowse link
G Supt5 suppressor of Ty 5, DSIF elongation factor subunit increases expression ISO geraniol results in increased expression of SUPT5H mRNA CTD PMID:27683099 NCBI chr 7:28,314,891...28,338,804
Ensembl chr 7:28,314,891...28,338,746
JBrowse link
G Tardbp TAR DNA binding protein decreases expression ISO geraniol results in decreased expression of TARDBP mRNA CTD PMID:27683099 NCBI chr 4:148,612,382...148,627,084
Ensembl chr 4:148,612,382...148,627,019
JBrowse link
G Tceal1 transcription elongation factor A (SII)-like 1 increases expression ISO geraniol results in increased expression of TCEAL1 mRNA CTD PMID:27683099 NCBI chr  X:136,707,982...136,709,873
Ensembl chr  X:136,707,982...136,711,478
JBrowse link
G Tcf12 transcription factor 12 increases expression ISO geraniol results in increased expression of TCF12 mRNA CTD PMID:27683099 NCBI chr 9:71,844,252...72,111,893
Ensembl chr 9:71,842,688...72,111,871
JBrowse link
G Tcf25 transcription factor 25 (basic helix-loop-helix) increases expression ISO geraniol results in increased expression of TCF25 mRNA CTD PMID:27683099 NCBI chr 8:123,370,772...123,404,174
Ensembl chr 8:123,373,753...123,403,835
JBrowse link
G Tcf4 transcription factor 4 decreases expression ISO geraniol results in decreased expression of TCF4 mRNA CTD PMID:27683099 NCBI chr18:69,343,429...69,687,967
Ensembl chr18:69,343,356...69,689,079
JBrowse link
G Tcf7l2 transcription factor 7 like 2, T cell specific, HMG box decreases expression ISO geraniol results in decreased expression of TCF7L2 mRNA CTD PMID:27683099 NCBI chr19:55,741,797...55,933,659
Ensembl chr19:55,741,820...55,933,654
JBrowse link
G Terf1 telomeric repeat binding factor 1 decreases expression ISO geraniol results in decreased expression of TERF1 mRNA CTD PMID:27683099 NCBI chr 1:15,805,546...15,844,052
Ensembl chr 1:15,805,646...15,844,052
JBrowse link
G Tfap2a transcription factor AP-2, alpha increases expression ISO geraniol results in increased expression of TFAP2A mRNA CTD PMID:27683099 NCBI chr13:40,713,802...40,738,238
Ensembl chr13:40,715,302...40,738,376
JBrowse link
G Tfcp2 transcription factor CP2 decreases expression ISO geraniol results in decreased expression of TFCP2 mRNA CTD PMID:27683099 NCBI chr15:100,497,781...100,552,014
Ensembl chr15:100,498,012...100,552,008
JBrowse link
G Tfdp1 transcription factor Dp 1 decreases expression ISO geraniol results in decreased expression of TFDP1 mRNA CTD PMID:27683099 NCBI chr 8:13,338,725...13,378,448
Ensembl chr 8:13,338,751...13,378,448
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of TGFB1 mRNA] CTD PMID:28428697 NCBI chr 7:25,687,002...25,705,077
Ensembl chr 7:25,687,002...25,705,077
JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 increases expression ISO geraniol results in increased expression of TGIF1 mRNA CTD PMID:27683099 NCBI chr17:70,844,205...70,853,532
Ensembl chr17:70,844,205...70,853,546
JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein] CTD PMID:23943375 NCBI chr 7:142,892,779...142,899,995
Ensembl chr 7:142,892,752...142,931,128
JBrowse link
G Timeless timeless circadian clock 1 decreases expression ISO geraniol results in decreased expression of TIMELESS mRNA CTD PMID:27683099 NCBI chr10:128,232,063...128,252,941
Ensembl chr10:128,232,065...128,252,941
JBrowse link
G Tk1 thymidine kinase 1 decreases expression
multiple interactions
ISO geraniol results in decreased expression of TK1 mRNA
Fluorouracil promotes the reaction [geraniol results in decreased expression of TK1 mRNA]
CTD PMID:15374632 NCBI chr11:117,815,519...117,826,087
Ensembl chr11:117,815,526...117,826,092
JBrowse link
G Tle1 transducin-like enhancer of split 1 increases expression ISO geraniol results in increased expression of TLE1 mRNA CTD PMID:27683099 NCBI chr 4:72,109,945...72,200,989
Ensembl chr 4:72,117,142...72,200,919
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TLR4 mRNA]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TLR4 protein] CTD PMID:29050341 NCBI chr 4:66,827,551...66,846,581
Ensembl chr 4:66,827,584...66,930,284
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO
EXP
geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of TNF protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]
2-chloro-5-nitrobenzanilide inhibits the reaction [geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of TNF protein]]; geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of TNF protein]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]]; geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]]; geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]]
geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of TNF protein]; geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF protein]; geraniol inhibits the reaction [Fructose results in increased secretion of TNF protein]
geraniol results in increased expression of TNF mRNA
CTD PMID:21430599 PMID:23399806 PMID:25679220 PMID:26190278 PMID:26695085 PMID:26973525 PMID:28358702 PMID:28397014 PMID:29050341 PMID:30254419 PMID:30550845 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tpx2 TPX2, microtubule-associated decreases expression ISO geraniol results in decreased expression of TPX2 mRNA CTD PMID:27683099 NCBI chr 2:152,847,964...152,895,321
Ensembl chr 2:152,847,964...152,895,321
JBrowse link
G Traip TRAF-interacting protein decreases expression ISO geraniol results in decreased expression of TRAIP mRNA CTD PMID:27683099 NCBI chr 9:107,950,325...107,972,270
Ensembl chr 9:107,950,136...107,972,270
JBrowse link
G Trak1 trafficking protein, kinesin binding 1 increases expression ISO geraniol results in increased expression of TRAK1 mRNA CTD PMID:27683099 NCBI chr 9:121,297,502...121,474,919
Ensembl chr 9:121,297,502...121,474,918
JBrowse link
G Trim29 tripartite motif-containing 29 increases expression ISO geraniol results in increased expression of TRIM29 mRNA CTD PMID:27683099 NCBI chr 9:43,310,715...43,336,125
Ensembl chr 9:43,310,848...43,336,115
JBrowse link
G Trp53 transformation related protein 53 multiple interactions
increases expression
ISO geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 mRNA]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 protein]
geraniol results in increased expression of TP53 mRNA
CTD PMID:21907755 PMID:27683099 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
G Trps1 transcriptional repressor GATA binding 1 increases expression ISO geraniol results in increased expression of TRPS1 mRNA CTD PMID:27683099 NCBI chr15:50,654,757...50,890,631
Ensembl chr15:50,654,752...50,890,463
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions ISO geraniol binds to and results in increased activity of TRPV1 protein CTD PMID:20686244 NCBI chr11:73,234,149...73,261,322
Ensembl chr11:73,234,292...73,261,242
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 increases expression ISO geraniol results in increased expression of TSC22D3 mRNA CTD PMID:27683099 NCBI chr  X:140,539,528...140,600,522
Ensembl chr  X:140,539,528...140,600,659
JBrowse link
G Ttk Ttk protein kinase decreases expression ISO geraniol results in decreased expression of TTK mRNA CTD PMID:27683099 NCBI chr 9:83,834,651...83,872,390
Ensembl chr 9:83,834,689...83,872,389
JBrowse link
G Tulp3 tubby-like protein 3 increases expression ISO geraniol results in increased expression of TULP3 mRNA CTD PMID:27683099 NCBI chr 6:128,321,140...128,355,873
Ensembl chr 6:128,321,161...128,355,851
JBrowse link
G Tulp4 tubby like protein 4 increases expression ISO geraniol results in increased expression of TULP4 mRNA CTD PMID:27683099 NCBI chr17:6,106,253...6,240,637
Ensembl chr17:6,106,437...6,251,128
JBrowse link
G Tyms thymidylate synthase multiple interactions
decreases expression
ISO Fluorouracil promotes the reaction [geraniol results in decreased expression of TYMS mRNA] CTD PMID:15374632 NCBI chr 5:30,038,546...30,073,645
Ensembl chr 5:30,058,202...30,073,617
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C decreases expression ISO geraniol results in decreased expression of UBE2C mRNA CTD PMID:27683099 NCBI chr 2:164,769,929...164,772,902
Ensembl chr 2:164,769,898...164,778,822
JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N decreases expression ISO geraniol results in decreased expression of UBE2N mRNA CTD PMID:27683099 NCBI chr10:95,515,162...95,545,658
Ensembl chr10:95,515,145...95,545,657
JBrowse link
G Ubp1 upstream binding protein 1 decreases expression ISO geraniol results in decreased expression of UBP1 mRNA CTD PMID:27683099 NCBI chr 9:113,930,939...113,978,027
Ensembl chr 9:113,930,934...113,977,202
JBrowse link
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) multiple interactions ISO geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of UCP2 protein] CTD PMID:26695085 NCBI chr 7:100,493,337...100,499,629
Ensembl chr 7:100,493,337...100,502,020
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions EXP
ISO
geraniol inhibits the reaction [Dietary Fats results in increased expression of VCAM1 protein]
geraniol inhibits the reaction [Palmitic Acid results in increased expression of VCAM1 protein]
CTD PMID:27107694 NCBI chr 3:116,110,020...116,129,688
Ensembl chr 3:116,109,949...116,129,688
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of VEGFA protein] CTD PMID:26364502 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link
G Vldlr very low density lipoprotein receptor increases expression EXP geraniol results in increased expression of VLDLR mRNA CTD PMID:26141755 NCBI chr19:27,216,480...27,254,231
Ensembl chr19:27,216,484...27,254,231
JBrowse link
G Xbp1 X-box binding protein 1 increases expression ISO geraniol results in increased expression of XBP1 mRNA CTD PMID:27683099 NCBI chr11:5,520,641...5,525,993
Ensembl chr11:5,520,659...5,525,893
JBrowse link
G Zbtb1 zinc finger and BTB domain containing 1 increases expression ISO geraniol results in increased expression of ZBTB1 mRNA CTD PMID:27683099 NCBI chr12:76,370,051...76,396,955
Ensembl chr12:76,370,266...76,396,950
JBrowse link
G Zbtb10 zinc finger and BTB domain containing 10 increases expression ISO geraniol results in increased expression of ZBTB10 mRNA CTD PMID:27683099 NCBI chr 3:9,250,567...9,285,333
Ensembl chr 3:9,250,602...9,285,333
JBrowse link
G Zbtb11 zinc finger and BTB domain containing 11 decreases expression ISO geraniol results in decreased expression of ZBTB11 mRNA CTD PMID:27683099 NCBI chr16:55,971,437...56,008,913
Ensembl chr16:55,973,883...56,008,913
JBrowse link
G Zbtb20 zinc finger and BTB domain containing 20 increases expression ISO geraniol results in increased expression of ZBTB20 mRNA CTD PMID:27683099 NCBI chr16:42,875,689...43,634,392
Ensembl chr16:42,875,881...43,642,602
JBrowse link
G Zfp110 zinc finger protein 110 increases expression ISO geraniol results in increased expression of ZNF274 mRNA CTD PMID:27683099 NCBI chr 7:12,834,761...12,850,586
Ensembl chr 7:12,834,761...12,850,577
JBrowse link
G Zfp189 zinc finger protein 189 increases expression ISO geraniol results in increased expression of ZNF189 mRNA CTD PMID:27683099 NCBI chr 4:49,521,176...49,531,558
Ensembl chr 4:49,521,176...49,531,517
JBrowse link
G Zfp207 zinc finger protein 207 decreases expression ISO geraniol results in decreased expression of ZNF207 mRNA CTD PMID:27683099 NCBI chr11:80,383,279...80,408,561
Ensembl chr11:80,383,279...80,405,733
JBrowse link
G Zfp248 zinc finger protein 248 decreases expression ISO geraniol results in decreased expression of ZNF248 mRNA CTD PMID:27683099 NCBI chr 6:118,427,319...118,455,699
Ensembl chr 6:118,427,319...118,455,528
JBrowse link
G Zfp263 zinc finger protein 263 increases expression ISO geraniol results in increased expression of ZNF263 mRNA CTD PMID:27683099 NCBI chr16:3,744,099...3,750,790
Ensembl chr16:3,744,093...3,750,790
JBrowse link
G Zfp264 zinc finger protein 264 increases expression ISO geraniol results in increased expression of ZNF264 mRNA CTD PMID:27683099 NCBI chr 7:6,977,445...6,990,228
Ensembl chr 7:6,977,246...6,991,087
JBrowse link
G Zfp281 zinc finger protein 281 increases expression ISO geraniol results in increased expression of ZNF281 mRNA CTD PMID:27683099 NCBI chr 1:136,624,901...136,630,391
Ensembl chr 1:136,624,901...136,630,053
JBrowse link
G Zfp300 zinc finger protein 300 increases expression ISO geraniol results in increased expression of ZNF84 mRNA CTD PMID:27683099 NCBI chr  X:21,078,208...21,089,698
Ensembl chr  X:21,079,174...21,089,527
JBrowse link
G Zfp329 zinc finger protein 329 increases expression ISO geraniol results in increased expression of ZNF329 mRNA CTD PMID:27683099 NCBI chr 7:12,803,778...12,818,895
Ensembl chr 7:12,804,977...12,818,858
JBrowse link
G Zfp334 zinc finger protein 334 increases expression ISO geraniol results in increased expression of ZNF334 mRNA CTD PMID:27683099 NCBI chr 2:165,374,264...165,388,315
Ensembl chr 2:165,374,264...165,388,259
JBrowse link
G Zfp354a zinc finger protein 354A increases expression ISO geraniol results in increased expression of ZNF354A mRNA CTD PMID:27683099 NCBI chr11:51,059,225...51,072,799
Ensembl chr11:51,059,257...51,072,799
JBrowse link
G Zfp410 zinc finger protein 410 increases expression ISO geraniol results in increased expression of ZNF410 mRNA CTD PMID:27683099 NCBI chr12:84,316,510...84,344,439
Ensembl chr12:84,316,852...84,343,723
JBrowse link
G Zfp467 zinc finger protein 467 increases expression ISO geraniol results in increased expression of ZNF467 mRNA CTD PMID:27683099 NCBI chr 6:48,427,692...48,445,992
Ensembl chr 6:48,427,697...48,445,825
JBrowse link
G Zfp606 zinc finger protein 606 increases expression ISO geraniol results in increased expression of ZNF606 mRNA CTD PMID:27683099 NCBI chr 7:12,478,280...12,496,235
Ensembl chr 7:12,478,293...12,496,235
JBrowse link
G Zfp612 zinc finger protein 612 increases expression ISO geraniol results in increased expression of ZNF23 mRNA CTD PMID:27683099 NCBI chr 8:110,079,705...110,092,753
Ensembl chr 8:110,079,746...110,092,741
JBrowse link
G Zfp768 zinc finger protein 768 increases expression ISO geraniol results in increased expression of ZNF768 mRNA CTD PMID:27683099 NCBI chr 7:127,342,795...127,345,314
Ensembl chr 7:127,342,795...127,345,589
JBrowse link
G Zhx2 zinc fingers and homeoboxes 2 increases expression ISO geraniol results in increased expression of ZHX2 mRNA CTD PMID:27683099 NCBI chr15:57,694,667...57,839,832
Ensembl chr15:57,694,665...57,839,832
JBrowse link
G Zkscan14 zinc finger with KRAB and SCAN domains 14 increases expression ISO geraniol results in increased expression of ZNF394 mRNA CTD PMID:27683099 NCBI chr 5:145,194,946...145,204,164
Ensembl chr 5:145,194,946...145,201,868
JBrowse link
G Zmiz1 zinc finger, MIZ-type containing 1 increases expression ISO geraniol results in increased expression of ZMIZ1 mRNA CTD PMID:27683099 NCBI chr14:25,457,875...25,666,743
Ensembl chr14:25,459,185...25,666,743
JBrowse link
G Zmym4 zinc finger, MYM-type 4 increases expression ISO geraniol results in increased expression of ZMYM4 mRNA CTD PMID:27683099 NCBI chr 4:126,861,819...126,969,377
Ensembl chr 4:126,861,939...126,968,135
JBrowse link
G Zmynd11 zinc finger, MYND domain containing 11 increases expression ISO geraniol results in increased expression of ZMYND11 mRNA CTD PMID:27683099 NCBI chr13:9,684,836...9,766,014
Ensembl chr13:9,684,833...9,765,330
JBrowse link
G Zscan18 zinc finger and SCAN domain containing 18 increases expression ISO geraniol results in increased expression of ZSCAN18 mRNA CTD PMID:27683099 NCBI chr 7:12,768,090...12,811,666
Ensembl chr 7:12,768,090...12,803,635
JBrowse link
G Zzz3 zinc finger, ZZ domain containing 3 increases expression ISO geraniol results in increased expression of ZZZ3 mRNA CTD PMID:27683099 NCBI chr 3:152,395,473...152,462,826
Ensembl chr 3:152,395,473...152,462,826
JBrowse link
geranyl acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2-associated X protein increases expression ISO geranyl acetate results in increased expression of BAX protein CTD PMID:29745075 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression ISO geranyl acetate results in decreased expression of BCL2 protein CTD PMID:29745075 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
geranyl diphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase multiple interactions
increases abundance
ISO [geranylgeraniol co-treated with geranyl pyrophosphate] results in decreased expression of HMGCR protein; Lovastatin inhibits the reaction [HMGCR protein results in increased abundance of geranyl diphosphate] CTD PMID:19819230 PMID:19856009 NCBI chr13:96,648,962...96,670,936
Ensembl chr13:96,648,967...96,670,936
JBrowse link
G Mvk mevalonate kinase multiple interactions
decreases activity
ISO geranyl diphosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; geranyl diphosphate inhibits the reaction [MVK protein results in increased phosphorylation of Mevalonic Acid]
geranyl diphosphate results in decreased activity of MVK protein
CTD PMID:9392419 NCBI chr 5:114,444,264...114,460,591
Ensembl chr 5:114,444,269...114,460,591
JBrowse link
G Rap1a RAS-related protein 1a multiple interactions ISO [geranylgeraniol co-treated with geranyl pyrophosphate] results in decreased expression of RAP1A protein modified form CTD PMID:19819230 NCBI chr 3:105,727,260...105,801,394
Ensembl chr 3:105,727,267...105,801,336
JBrowse link
geranylgeraniol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b10 aldo-keto reductase family 1, member B10 (aldose reductase) increases chemical synthesis ISO AKR1B10 protein results in increased chemical synthesis of geranylgeraniol CTD PMID:21187079 NCBI chr 6:34,384,247...34,396,949
Ensembl chr 6:34,384,218...34,396,950
JBrowse link
G Akr1c18 aldo-keto reductase family 1, member C18 increases chemical synthesis ISO AKR1C3 protein results in increased chemical synthesis of geranylgeraniol CTD PMID:21187079 NCBI chr13:4,132,615...4,150,646
Ensembl chr13:4,132,615...4,150,654
JBrowse link
G Casp3 caspase 3 increases activity ISO geranylgeraniol results in increased activity of CASP3 protein CTD PMID:9175767 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Cav1 caveolin 1, caveolae protein multiple interactions ISO geranylgeraniol inhibits the reaction [rosiglitazone results in increased expression of CAV1 mRNA] CTD PMID:15314095 NCBI chr 6:17,306,335...17,341,328
Ensembl chr 6:17,306,335...17,341,452
JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions ISO geranylgeraniol inhibits the reaction [Zoledronic Acid results in decreased expression of CCN1 protein] CTD PMID:19530242 NCBI chr 3:145,646,971...145,649,985
Ensembl chr 3:145,646,976...145,649,981
JBrowse link
G Egf epidermal growth factor multiple interactions ISO geranylgeraniol analog inhibits the reaction [EGF protein results in increased phosphorylation of RHOA protein] CTD PMID:24587105 NCBI chr 3:129,677,574...129,755,322
Ensembl chr 3:129,677,565...129,755,316
JBrowse link
G F3 coagulation factor III multiple interactions ISO geranylgeraniol inhibits the reaction [Fluvastatin results in decreased expression of F3 protein]; geranylgeraniol inhibits the reaction [Simvastatin results in decreased expression of F3] CTD PMID:9081680 PMID:12753293 NCBI chr 3:121,723,537...121,735,052
Ensembl chr 3:121,723,537...121,735,048
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase multiple interactions
decreases activity
ISO [geranylgeraniol co-treated with geranyl pyrophosphate] results in decreased expression of HMGCR protein; [MVK gene mutant form results in increased activity of HMGCR protein] which results in increased susceptibility to geranylgeraniol; MVK gene mutant form promotes the reaction [geranylgeraniol results in decreased activity of HMGCR protein] CTD PMID:12477733 PMID:19819230 NCBI chr13:96,648,962...96,670,936
Ensembl chr13:96,648,967...96,670,936
JBrowse link
G Ibsp integrin binding sialoprotein multiple interactions ISO geranylgeraniol inhibits the reaction [zoledronic acid results in increased expression of IBSP mRNA] CTD PMID:15324309 NCBI chr 5:104,299,287...104,311,472
Ensembl chr 5:104,299,171...104,311,469
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
geranylgeraniol inhibits the reaction [[MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased expression of IL1B protein]
geranylgeraniol inhibits the reaction [[Alendronate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]
CTD PMID:20304105 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Itga2 integrin alpha 2 multiple interactions ISO geranylgeraniol inhibits the reaction [Atorvastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]]; geranylgeraniol inhibits the reaction [Pravastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]] CTD PMID:12500026 NCBI chr13:114,833,081...114,932,100
Ensembl chr13:114,833,081...114,932,100
JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) multiple interactions ISO geranylgeraniol inhibits the reaction [Atorvastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]]; geranylgeraniol inhibits the reaction [Pravastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]] CTD PMID:12500026 NCBI chr 8:128,685,654...128,733,579
Ensembl chr 8:128,685,654...128,733,200
JBrowse link
G Mvk mevalonate kinase multiple interactions ISO [MVK gene mutant form results in increased activity of HMGCR protein] which results in increased susceptibility to geranylgeraniol; geranylgeraniol inhibits the reaction [[MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased expression of IL1B protein]; geranylgeraniol inhibits the reaction [MVK gene mutant form results in increased susceptibility to Lipopolysaccharides]; MVK gene mutant form promotes the reaction [geranylgeraniol results in decreased activity of HMGCR protein] CTD PMID:12477733 PMID:20304105 NCBI chr 5:114,444,264...114,460,591
Ensembl chr 5:114,444,269...114,460,591
JBrowse link
G Myl9 myosin, light polypeptide 9, regulatory multiple interactions ISO geranylgeraniol analog inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MYL9 protein] CTD PMID:24587105 NCBI chr 2:156,775,408...156,781,657
Ensembl chr 2:156,775,420...156,781,658
JBrowse link
G Plat plasminogen activator, tissue multiple interactions ISO geranylgeraniol inhibits the reaction [Simvastatin results in increased expression of PLAT mRNA]; geranylgeraniol inhibits the reaction [Simvastatin results in increased expression of PLAT] CTD PMID:12371961 PMID:12753293 NCBI chr 8:22,757,722...22,782,848
Ensembl chr 8:22,757,727...22,782,844
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO geranylgeraniol inhibits the reaction [cerivastatin promotes the reaction [Bezafibrate results in increased activity of [PPARA protein binds to RXRA protein]]] CTD PMID:11779144 NCBI chr15:85,734,910...85,806,851
Ensembl chr15:85,734,983...85,802,819
JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A multiple interactions ISO geranylgeraniol inhibits the reaction [Simvastatin inhibits the reaction [Phenylephrine results in increased phosphorylation of PPP1R12A protein]] CTD PMID:24449418 NCBI chr10:108,162,092...108,279,985
Ensembl chr10:108,162,193...108,284,475
JBrowse link
G Ppp1r14a protein phosphatase 1, regulatory inhibitor subunit 14A multiple interactions ISO geranylgeraniol inhibits the reaction [Simvastatin inhibits the reaction [Phenylephrine results in increased phosphorylation of PPP1R14A protein]] CTD PMID:24449418 NCBI chr 7:29,289,320...29,293,390
Ensembl chr 7:29,289,308...29,293,801
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO geranylgeraniol inhibits the reaction [Lovastatin affects the localization of RAC1 protein] CTD PMID:12933658 NCBI chr 5:143,505,481...143,528,031
Ensembl chr 5:143,503,634...143,528,036
JBrowse link
G Rap1a RAS-related protein 1a multiple interactions ISO [geranylgeraniol co-treated with geranyl pyrophosphate] results in decreased expression of RAP1A protein modified form; geranylgeraniol inhibits the reaction [zoledronic acid results in decreased geranoylation of RAP1A protein] CTD PMID:16539721 PMID:19819230 NCBI chr 3:105,727,260...105,801,394
Ensembl chr 3:105,727,267...105,801,336
JBrowse link
G Rhoa ras homolog family member A multiple interactions ISO geranylgeraniol analog inhibits the reaction [EGF protein results in increased phosphorylation of RHOA protein]; geranylgeraniol analog inhibits the reaction [lysophosphatidic acid results in increased activity of RHOA protein]; geranylgeraniol inhibits the reaction [Lovastatin affects the localization of RHOA protein]; geranylgeraniol inhibits the reaction [Simvastatin results in decreased geranoylation of and affects the localization of RHOA protein]; geranylgeraniol inhibits the reaction [Zoledronic Acid results in decreased expression of and affects the localization of RHOA protein]
geranylgeraniol inhibits the reaction [Lovastatin affects the localization of RHOA protein]; geranylgeraniol inhibits the reaction [Simvastatin inhibits the reaction [Phenylephrine results in increased activity of RHOA protein]]
CTD PMID:9398081 PMID:12477733 PMID:12933658 PMID:15324309 PMID:24449418 PMID:24587105 NCBI chr 9:108,306,160...108,337,943
Ensembl chr 9:108,306,129...108,337,934
JBrowse link
G Rhoc ras homolog family member C multiple interactions ISO geranylgeraniol analog inhibits the reaction [lysophosphatidic acid results in increased activity of RHOC protein] CTD PMID:24587105 NCBI chr 3:104,789,034...104,794,459
Ensembl chr 3:104,788,375...104,794,459
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO geranylgeraniol inhibits the reaction [cerivastatin promotes the reaction [Bezafibrate results in increased activity of [PPARA protein binds to RXRA protein]]] CTD PMID:11779144 NCBI chr 2:27,676,445...27,763,319
Ensembl chr 2:27,676,440...27,762,957
JBrowse link
G Sele selectin, endothelial cell multiple interactions ISO geranylgeraniol inhibits the reaction [Simvastatin promotes the reaction [TNF protein results in increased expression of SELE protein]] CTD PMID:16740276 NCBI chr 1:164,039,614...164,058,487
Ensembl chr 1:164,048,234...164,057,677
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO geranylgeraniol inhibits the reaction [Simvastatin promotes the reaction [TNF protein results in increased expression of SELE protein]] CTD PMID:16740276 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
solanesol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO 2-phenylacetylenesulfonamide inhibits the reaction [solanesol inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]]; solanesol inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]; solanesol promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]]; tin protoporphyrin IX inhibits the reaction [solanesol inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]] CTD PMID:25645596 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Cul3 cullin 3 multiple interactions ISO solanesol inhibits the reaction [KEAP1 protein binds to CUL3 protein binds to RBX1 protein] CTD PMID:25645596 NCBI chr 1:80,264,923...80,340,690
Ensembl chr 1:80,264,923...80,340,480
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO geldanamycin inhibits the reaction [solanesol results in increased expression of HMOX1 mRNA]; geldanamycin inhibits the reaction [solanesol results in increased expression of HMOX1 protein]
solanesol results in increased expression of HMOX1 mRNA; solanesol results in increased expression of HMOX1 protein
CTD PMID:25645596 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Hsf1 heat shock factor 1 multiple interactions
affects localization
ISO 2-phenylacetylenesulfonamide inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; geldanamycin inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; N2-(1H-indazole-5-yl)-N6-methyl-3-nitropyridine-2,6-diamine inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]
solanesol affects the localization of HSF1 protein
CTD PMID:25645596 NCBI chr15:76,477,362...76,501,155
Ensembl chr15:76,477,422...76,501,913
JBrowse link
G Keap1 kelch-like ECH-associated protein 1 multiple interactions ISO solanesol inhibits the reaction [KEAP1 protein binds to CUL3 protein binds to RBX1 protein]; solanesol inhibits the reaction [KEAP1 protein binds to NFE2L2 protein] CTD PMID:25645596 NCBI chr 9:21,229,730...21,239,332
Ensembl chr 9:21,229,730...21,239,361
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions ISO solanesol affects the localization of and results in increased activity of NFE2L2 protein; solanesol inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]; solanesol results in decreased ubiquitination of and results in decreased degradation of NFE2L2 protein CTD PMID:25645596 NCBI chr 2:75,675,513...75,704,663
Ensembl chr 2:75,675,513...75,704,641
JBrowse link
G Rbx1 ring-box 1 multiple interactions ISO solanesol inhibits the reaction [KEAP1 protein binds to CUL3 protein binds to RBX1 protein] CTD PMID:25645596 NCBI chr15:81,466,316...81,476,369
Ensembl chr15:81,466,296...81,476,369
JBrowse link
G Stub1 STIP1 homology and U-Box containing protein 1 multiple interactions ISO 2-phenylacetylenesulfonamide inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; geldanamycin inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; N2-(1H-indazole-5-yl)-N6-methyl-3-nitropyridine-2,6-diamine inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; solanesol promotes the reaction [HSF1 protein binds to STUB1 protein] CTD PMID:25645596 NCBI chr17:25,830,634...25,832,919
Ensembl chr17:25,830,505...25,833,404
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21720
    chemical entity 21718
      atom 21706
        nonmetal atom 21598
          carbon atom 21327
            organic molecular entity 21327
              isoprenoid 13223
                prenols 512
                  polyprenol 503
                    (2E,6E,10E)-omega-hydroxyfarnesol 0
                    3,7-dimethylocta-2,6-dien-1-ol + 390
                    Dolichol-16 0
                    Dolichol-17 0
                    Dolichol-18 0
                    Dolichol-19 0
                    archaeal dolichol + 0
                    decaprenol 0
                    ditrans,polycis-polyprenol 0
                    dolichol + 1
                    farnesol + 103
                    geranylgeraniol + 25
                    hexaprenols + 0
                    nonaprenol + 8
                    octaprenols + 0
                    omega-hydroxygeranylgeraniol 0
                    polyprenol phosphate + 64
                    undecaprenols + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 21720
    subatomic particle 21706
      composite particle 21706
        hadron 21706
          baryon 21706
            nucleon 21706
              atomic nucleus 21706
                atom 21706
                  main group element atom 21621