polyene antibiotic - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	polyene antibiotic	go back to main search page
Accession:	CHEBI:26177	browse the term
Definition:	A family of antibiotics containing a conjugated polyene moiety, usuallly isolated from some species of Streptomyces.
Synonyms:	related_synonym:	polyene antibiotics

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Rat (357) Mouse (360) Human (394) Chinchilla (0) Bonobo (0) Dog (4) Squirrel (0) Pig (1) Green Monkey (0) Naked Mole-rat (0) All
Genes (394)

amphotericin B

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily A member 1

multiple interactions

[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of ABCA1 mRNA

NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155

G

ATP binding cassette subfamily A member 12

decreases expression

Amphotericin B analog results in decreased expression of ABCA12 mRNA

NCBI chr 2:214,931,542...215,138,626
Ensembl chr 2:214,931,542...215,138,626

G

ATP binding cassette subfamily B member 1

multiple interactions

[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCB1A mRNA

NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323

G

ATP binding cassette subfamily B member 11

multiple interactions

[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCB11 mRNA

NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324

G

ATP binding cassette subfamily C member 2

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCC2 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCC2 mRNA

NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594

G

ATP binding cassette subfamily C member 3

multiple interactions

[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCC3 mRNA

NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253

G

ATP binding cassette subfamily G member 1

decreases expression

Amphotericin B analog results in decreased expression of ABCG1 mRNA

NCBI chr21:42,199,689...42,297,244
Ensembl chr21:42,199,689...42,297,244

G

ATP binding cassette subfamily G member 2 (JR blood group)

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCG2 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCG2 mRNA

NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628

G

ATP binding cassette subfamily G member 5

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of ABCG5 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of ABCG5 mRNA

NCBI chr 2:43,806,211...43,839,231
Ensembl chr 2:43,812,472...43,838,865

G

acrosomal vesicle protein 1

increases expression

Amphotericin B analog results in increased expression of ACRV1 mRNA

NCBI chr11:125,671,522...125,680,847
Ensembl chr11:125,671,522...125,680,874

G

ADAM metallopeptidase with thrombospondin type 1 motif 12

increases expression

Amphotericin B analog results in increased expression of ADAMTS12 mRNA

NCBI chr 5:33,523,535...33,891,990
Ensembl chr 5:33,523,535...33,892,019

G

adenylate cyclase 2

increases expression

Amphotericin B analog results in increased expression of ADCY2 mRNA

NCBI chr 5:7,396,138...7,830,081
Ensembl chr 5:7,396,138...7,830,081

G

adenosine A3 receptor

increases expression

Amphotericin B analog results in increased expression of ADORA3 mRNA

NCBI chr 1:111,499,429...111,503,633
Ensembl chr 1:111,499,429...111,503,633

G

adrenoceptor alpha 2A

decreases expression

Amphotericin B analog results in decreased expression of ADRA2A mRNA

NCBI chr10:111,077,029...111,080,907
Ensembl chr10:111,077,029...111,080,907

G

aldehyde dehydrogenase 8 family member A1

decreases expression

Amphotericin B analog results in decreased expression of ALDH8A1 mRNA

NCBI chr 6:134,917,393...134,950,101
Ensembl chr 6:134,917,393...134,950,115

G

ALK receptor tyrosine kinase

increases expression

Amphotericin B results in increased expression of ALK mRNA

NCBI chr 2:29,192,774...29,921,586
Ensembl chr 2:29,192,774...29,921,586

G

arachidonate 5-lipoxygenase

decreases expression

Amphotericin B analog results in decreased expression of ALOX5 mRNA

NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119

G

alpha-methylacyl-CoA racemase

decreases expression

Amphotericin B analog results in decreased expression of AMACR mRNA

NCBI chr 5:33,986,165...34,008,050
Ensembl chr 5:33,986,165...34,008,104

G

ankyrin 3

decreases expression

Amphotericin B analog results in decreased expression of ANK3 mRNA

NCBI chr10:60,026,298...60,733,528
Ensembl chr10:60,026,298...60,733,490

G

annexin A9

decreases expression

Amphotericin B analog results in decreased expression of ANXA9 mRNA

NCBI chr 1:150,977,306...150,995,634
Ensembl chr 1:150,982,249...150,995,634

G

adaptor related protein complex 3 subunit beta 2

increases expression

Amphotericin B analog results in increased expression of AP3B2 mRNA

NCBI chr15:82,659,281...82,709,875
Ensembl chr15:82,659,281...82,710,112

G

amyloid beta precursor protein binding family B member 2

increases expression

Amphotericin B analog results in increased expression of APBB2 mRNA

NCBI chr 4:40,810,027...41,214,542
Ensembl chr 4:40,810,027...41,216,714

G

apolipoprotein C2

increases expression

Amphotericin B analog results in increased expression of APOC2 mRNA

NCBI chr19:44,946,051...44,949,565
Ensembl chr19:44,946,035...44,949,565

G

aquaporin 3 (Gill blood group)

decreases expression

Amphotericin B analog results in decreased expression of AQP3 mRNA

NCBI chr 9:33,441,160...33,447,593
Ensembl chr 9:33,441,156...33,447,596

G

aquaporin 5

increases expression

Amphotericin B analog results in increased expression of AQP5 mRNA

NCBI chr12:49,961,872...49,965,682
Ensembl chr12:49,961,872...49,965,682

G

arginase 2

decreases expression

Amphotericin B analog results in decreased expression of ARG2 mRNA

NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708

G

Rho guanine nucleotide exchange factor 26

increases expression

Amphotericin B results in increased expression of ARHGEF26 mRNA

NCBI chr 3:154,121,003...154,257,825
Ensembl chr 3:154,121,003...154,257,827

G

aryl hydrocarbon receptor nuclear translocator

multiple interactions

Amphotericin B inhibits the reaction [[HIF1A protein binds to ARNT protein] which binds to EPO enhancer]

NCBI chr 1:150,809,713...150,876,599
Ensembl chr 1:150,809,713...150,876,708

G

arrestin beta 1

increases expression

Amphotericin B analog results in increased expression of ARRB1 mRNA

NCBI chr11:75,260,122...75,351,661
Ensembl chr11:75,260,122...75,351,705

G

autophagy related 3

decreases expression

Amphotericin B results in decreased expression of ATG3 mRNA

NCBI chr 3:112,532,510...112,561,962
Ensembl chr 3:112,532,510...112,562,046

G

ATPase phospholipid transporting 10B (putative)

increases expression

Amphotericin B analog results in increased expression of ATP10B mRNA

NCBI chr 5:160,563,120...160,929,360
Ensembl chr 5:160,563,120...160,852,214

G

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4

increases expression

Amphotericin B analog results in increased expression of B3GNT4 mRNA

NCBI chr12:122,203,709...122,208,952
Ensembl chr12:122,203,681...122,208,952

G

BAG cochaperone 4

decreases expression

Amphotericin B analog results in decreased expression of BAG4 mRNA

NCBI chr 8:38,176,855...38,213,301
Ensembl chr 8:38,176,533...38,213,301

G

BCL6 transcription repressor

decreases expression

Amphotericin B analog results in decreased expression of BCL6 mRNA

NCBI chr 3:187,721,377...187,745,468
Ensembl chr 3:187,721,377...187,745,725

G

BEN domain containing 5

decreases expression

Amphotericin B analog results in decreased expression of BEND5 mRNA

NCBI chr 1:48,727,519...48,776,891
Ensembl chr 1:48,727,519...48,776,969

G

bone morphogenetic protein 2

decreases expression

Amphotericin B analog results in decreased expression of BMP2 mRNA; Amphotericin B results in decreased expression of BMP2 mRNA

NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246

G

bone morphogenetic protein 7

increases expression

Amphotericin B analog results in increased expression of BMP7 mRNA

NCBI chr20:57,168,753...57,266,641
Ensembl chr20:57,168,753...57,266,641

G

basonuclin zinc finger protein 1

increases expression

Amphotericin B analog results in increased expression of BNC1 mRNA

NCBI chr15:83,255,884...83,284,664
Ensembl chr15:83,255,884...83,284,664

G

BORA aurora kinase A activator

decreases expression

Amphotericin B analog results in decreased expression of BORA mRNA

NCBI chr13:72,727,923...72,756,196
Ensembl chr13:72,727,749...72,756,198

G

carbonic anhydrase 12

decreases expression

Amphotericin B analog results in decreased expression of CA12 mRNA

NCBI chr15:63,321,378...63,381,846
Ensembl chr15:63,321,378...63,381,846

G

carbonic anhydrase 14

increases expression

Amphotericin B analog results in increased expression of CA14 mRNA

NCBI chr 1:150,257,774...150,265,078
Ensembl chr 1:150,257,251...150,265,078

G

carbonic anhydrase 4

decreases expression

Amphotericin B analog results in decreased expression of CA4 mRNA

NCBI chr17:60,149,973...60,179,021
Ensembl chr17:60,149,942...60,170,899

G

carbonic anhydrase 9

decreases expression

Amphotericin B analog results in decreased expression of CA9 mRNA

NCBI chr 9:35,673,928...35,681,159
Ensembl chr 9:35,673,928...35,681,159

G

calcium/calmodulin dependent protein kinase II gamma

increases expression

Amphotericin B analog results in increased expression of CAMK2G mRNA

NCBI chr10:73,812,501...73,874,555
Ensembl chr10:73,812,501...73,874,591

G

calpain 6

decreases expression

Amphotericin B analog results in decreased expression of CAPN6 mRNA

NCBI chr X:111,245,099...111,270,483
Ensembl chr X:111,245,099...111,270,483

G

calcium responsive transcription factor

decreases expression

Amphotericin B analog results in decreased expression of CARF mRNA

NCBI chr 2:202,912,275...202,988,263
Ensembl chr 2:202,912,214...202,988,263

G

caspase 3

increases expression

Amphotericin B results in increased expression of CASP3 protein

NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062

G

calsequestrin 2

increases expression

Amphotericin B analog results in increased expression of CASQ2 mRNA

NCBI chr 1:115,700,021...115,768,714
Ensembl chr 1:115,700,021...115,768,884

G

catalase

decreases expression

Amphotericin B results in decreased expression of CAT mRNA

NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060

G

C-C motif chemokine ligand 20

increases expression

Amphotericin B analog results in increased expression of CCL20 mRNA; Amphotericin B results in increased expression of CCL20 mRNA

NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564

G

cyclin E2

decreases expression

Amphotericin B results in decreased expression of CCNE2 mRNA

NCBI chr 8:94,880,224...94,896,693
Ensembl chr 8:94,879,770...94,896,678

G

C-C motif chemokine receptor 2

decreases expression

Amphotericin B results in decreased expression of CCR2 mRNA

NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940

G

CD14 molecule

decreases expression

Amphotericin B analog results in decreased expression of CD14 mRNA

NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700

G

CD1c molecule

increases expression

Amphotericin B analog results in increased expression of CD1C mRNA

NCBI chr 1:158,289,923...158,294,774
Ensembl chr 1:158,289,923...158,294,774

G

CD1d molecule

decreases expression

Amphotericin B analog results in decreased expression of CD1D mRNA

NCBI chr 1:158,178,030...158,186,427
Ensembl chr 1:158,178,030...158,186,427

G

CD2 molecule

increases expression

Amphotericin B analog results in increased expression of CD2 mRNA

NCBI chr 1:116,754,430...116,769,229
Ensembl chr 1:116,754,430...116,769,229

G

CD3 epsilon subunit of T-cell receptor complex

increases expression

Amphotericin B analog results in increased expression of CD3E mRNA

NCBI chr11:118,304,730...118,316,173
Ensembl chr11:118,304,730...118,316,175

G

CD84 molecule

increases expression

Amphotericin B analog results in increased expression of CD84 mRNA

NCBI chr 1:160,541,098...160,579,496
Ensembl chr 1:160,541,095...160,579,516

G

cyclin dependent kinase like 5

increases expression

Amphotericin B analog results in increased expression of CDKL5 mRNA

NCBI chr X:18,425,608...18,653,629
Ensembl chr X:18,425,583...18,653,629

G

corneodesmosin

increases expression

Amphotericin B analog results in increased expression of CDSN mRNA

NCBI chr 6:31,115,087...31,120,446
Ensembl chr 6:31,115,087...31,120,446

G

CEA cell adhesion molecule 21

increases expression

Amphotericin B analog results in increased expression of CEACAM21 mRNA

NCBI chr19:41,549,518...41,586,844
Ensembl chr19:41,549,518...41,586,844

G

centrosomal protein 76

decreases expression

Amphotericin B analog results in decreased expression of CEP76 mRNA

NCBI chr18:12,661,956...12,702,777
Ensembl chr18:12,661,833...12,702,777

G

glycoprotein hormones, alpha polypeptide

increases expression

Amphotericin B analog results in increased expression of CGA mRNA

NCBI chr 6:87,085,498...87,095,106
Ensembl chr 6:87,085,498...87,095,106

G

ChaC glutathione specific gamma-glutamylcyclotransferase 1

increases expression

Amphotericin B analog results in increased expression of CHAC1 mRNA

NCBI chr15:40,953,471...40,956,512
Ensembl chr15:40,952,962...40,956,512

G

chitinase 3 like 1

decreases expression

Amphotericin B analog results in decreased expression of CHI3L1 mRNA

NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704

G

cell adhesion molecule L1 like

decreases expression

Amphotericin B analog results in decreased expression of CHL1 mRNA

NCBI chr 3:196,763...409,417
Ensembl chr 3:196,763...409,417

G

calcineurin like EF-hand protein 1

decreases expression

Amphotericin B analog results in decreased expression of CHP1 mRNA

NCBI chr15:41,231,268...41,281,887
Ensembl chr15:41,230,839...41,281,887

G

cholinergic receptor nicotinic beta 3 subunit

increases expression

Amphotericin B analog results in increased expression of CHRNB3 mRNA

NCBI chr 8:42,697,366...42,737,407
Ensembl chr 8:42,697,366...42,737,407

G

clusterin

affects expression
decreases expression

Amphotericin B affects the expression of CLU mRNA
Amphotericin B analog results in decreased expression of CLU mRNA

PMID:20623750 PMID:28534445

NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700

G

cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene

decreases expression

Amphotericin B analog results in decreased expression of CMAHP mRNA

NCBI chr 6:25,081,067...25,138,392
Ensembl chr 6:25,081,862...25,138,081

G

cannabinoid receptor 2

increases expression

Amphotericin B analog results in increased expression of CNR2 mRNA

NCBI chr 1:23,870,515...23,913,362
Ensembl chr 1:23,870,515...23,913,362

G

contactin 5

increases expression

Amphotericin B analog results in increased expression of CNTN5 mRNA

NCBI chr11:99,020,949...100,358,885
Ensembl chr11:99,020,949...100,358,885

G

collagen type V alpha 1 chain

increases expression

Amphotericin B analog results in increased expression of COL5A1 mRNA

NCBI chr 9:134,641,803...134,844,843
Ensembl chr 9:134,641,803...134,844,843

G

catechol-O-methyltransferase

increases expression

Amphotericin B analog results in increased expression of COMT mRNA

NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975

G

carboxypeptidase D

decreases expression

Amphotericin B analog results in decreased expression of CPD mRNA

NCBI chr17:30,378,927...30,469,989
Ensembl chr17:30,378,927...30,469,989

G

carnitine palmitoyltransferase 1B

decreases expression

Amphotericin B analog results in decreased expression of CPT1B mRNA

NCBI chr22:50,568,861...50,578,612
Ensembl chr22:50,568,861...50,578,465

G

cysteine rich secretory protein LCCL domain containing 2

increases expression

Amphotericin B analog results in increased expression of CRISPLD2 mRNA

NCBI chr16:84,819,985...84,909,508
Ensembl chr16:84,819,985...84,920,768

G

crystallin beta B1

increases expression

Amphotericin B analog results in increased expression of CRYBB1 mRNA

NCBI chr22:26,599,278...26,618,027
Ensembl chr22:26,599,278...26,618,027

G

colony stimulating factor 2

increases expression

Amphotericin B analog results in increased expression of CSF2 mRNA; Amphotericin B results in increased expression of CSF2 mRNA

NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170

G

chondroitin sulfate N-acetylgalactosaminyltransferase 2

increases expression

Amphotericin B analog results in increased expression of CSGALNACT2 mRNA

NCBI chr10:43,138,445...43,185,308
Ensembl chr10:43,138,445...43,185,302

G

chondroitin sulfate proteoglycan 5

decreases expression

Amphotericin B analog results in decreased expression of CSPG5 mRNA

NCBI chr 3:47,562,238...47,580,240
Ensembl chr 3:47,562,238...47,580,792

G

C-X-C motif chemokine ligand 1

increases expression

Amphotericin B analog results in increased expression of CXCL1 mRNA

NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308

G

C-X-C motif chemokine ligand 2

increases expression

Amphotericin B analog results in increased expression of CXCL2 mRNA; Amphotericin B results in increased expression of CXCL2 mRNA

NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196

G

C-X-C motif chemokine ligand 5

increases expression

Amphotericin B results in increased expression of CXCL5 mRNA

NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677

G

C-X-C motif chemokine ligand 8

increases expression
multiple interactions

Amphotericin B analog results in increased expression of CXCL8 mRNA; Amphotericin B results in increased expression of CXCL8 mRNA
[Amphotericin B co-treated with lipopolysaccharide, E. coli O26-B6] results in increased expression of CXCL8 mRNA

PMID:28534445 PMID:29594315

NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716

G

C-X-C motif chemokine receptor 4

decreases expression

Amphotericin B analog results in decreased expression of CXCR4 mRNA

NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177

G

cytochrome P450 family 27 subfamily A member 1

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP27A1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP27A1 mRNA

NCBI chr 2:218,782,147...218,815,293
Ensembl chr 2:218,781,749...218,815,293

G

cytochrome P450 family 2 subfamily C member 19

increases expression

Amphotericin B analog results in increased expression of CYP2C19 mRNA

NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547

G

cytochrome P450 family 4 subfamily A member 11

increases expression

Amphotericin B analog results in increased expression of CYP4A11 mRNA

NCBI chr 1:46,929,188...46,941,476
Ensembl chr 1:46,929,177...46,941,484

G

cytochrome P450 family 4 subfamily B member 1

decreases expression

Amphotericin B analog results in decreased expression of CYP4B1 mRNA

NCBI chr 1:46,799,046...46,819,413
Ensembl chr 1:46,757,838...46,819,413

G

cytochrome P450 family 7 subfamily A member 1

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP7A1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP7A1 mRNA

NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163

G

cytochrome P450 family 7 subfamily B member 1

multiple interactions

[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP7B1 mRNA

NCBI chr 8:64,586,575...64,798,737
Ensembl chr 8:64,587,763...64,798,737

G

cytochrome P450 family 8 subfamily B member 1

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP8B1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP8B1 mRNA

NCBI chr 3:42,872,192...42,875,879
Ensembl chr 3:42,856,005...42,875,898

G

cytohesin 4

increases expression

Amphotericin B analog results in increased expression of CYTH4 mRNA

NCBI chr22:37,282,508...37,315,341
Ensembl chr22:37,282,027...37,315,341

G

doublecortin like kinase 1

decreases expression

Amphotericin B analog results in decreased expression of DCLK1 mRNA

NCBI chr13:35,768,652...36,131,939
Ensembl chr13:35,768,652...36,131,382

G

dendrocyte expressed seven transmembrane protein

increases expression

Amphotericin B analog results in increased expression of DCSTAMP mRNA

NCBI chr 8:104,339,796...104,356,689
Ensembl chr 8:104,339,087...104,356,689

G

DNA damage inducible transcript 3

increases expression

Amphotericin B results in increased expression of DDIT3 mRNA

NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737

G

DDR1 divergent transcript

increases expression

Amphotericin B analog results in increased expression of DDR1-DT mRNA

Ensembl chr 6:30,866,982...30,875,918

G

DEAD/H-box helicase 11

increases expression

Amphotericin B results in increased expression of DDX11 mRNA

NCBI chr12:31,073,860...31,104,799
Ensembl chr12:31,073,860...31,104,799

G

DEAD/H-box helicase 12, pseudogene

increases expression

Amphotericin B results in increased expression of DDX12P mRNA

NCBI chr12:9,417,691...9,448,172
Ensembl chr12:9,418,673...9,448,229

G

DEP domain containing MTOR interacting protein

decreases expression

Amphotericin B analog results in decreased expression of DEPTOR mRNA

NCBI chr 8:119,873,722...120,050,918
Ensembl chr 8:119,873,717...120,050,918

G

dehydrogenase/reductase 7

decreases expression

Amphotericin B analog results in decreased expression of DHRS7 mRNA

NCBI chr14:60,144,119...60,169,889
Ensembl chr14:60,144,119...60,169,856

G

dicer 1, ribonuclease III

decreases expression

Amphotericin B analog results in decreased expression of DICER1 mRNA

NCBI chr14:95,086,228...95,158,010
Ensembl chr14:95,086,228...95,158,010

G

dickkopf WNT signaling pathway inhibitor 4

increases expression

Amphotericin B analog results in increased expression of DKK4 mRNA

NCBI chr 8:42,374,063...42,391,322
Ensembl chr 8:42,374,063...42,377,229

G

DLG associated protein 1

decreases expression
increases expression

Amphotericin B analog results in decreased expression of DLGAP1 mRNA
Amphotericin B analog results in increased expression of DLGAP1 mRNA

NCBI chr18:3,496,032...4,455,307
Ensembl chr18:3,496,032...4,455,307

G

dynein axonemal heavy chain 3

increases expression

Amphotericin B analog results in increased expression of DNAH3 mRNA

NCBI chr16:20,933,111...21,159,459
Ensembl chr16:20,933,111...21,159,441

G

DnaJ heat shock protein family (Hsp40) member A4

increases expression

Amphotericin B analog results in increased expression of DNAJA4 mRNA

NCBI chr15:78,264,145...78,282,191
Ensembl chr15:78,264,086...78,282,196

G

deltex E3 ubiquitin ligase 4

decreases expression

Amphotericin B analog results in decreased expression of DTX4 mRNA

NCBI chr11:59,171,430...59,208,588
Ensembl chr11:59,171,430...59,208,588

G

dual oxidase 2

increases expression

Amphotericin B analog results in increased expression of DUOX2 mRNA

NCBI chr15:45,092,650...45,114,172
Ensembl chr15:45,092,650...45,114,172

G

DAZ interacting zinc finger protein 3

decreases expression

Amphotericin B analog results in decreased expression of DZIP3 mRNA

NCBI chr 3:108,589,510...108,694,840
Ensembl chr 3:108,589,705...108,694,840

G

E2F transcription factor 2

increases expression

Amphotericin B analog results in increased expression of E2F2 mRNA

NCBI chr 1:23,505,212...23,531,233
Ensembl chr 1:23,506,438...23,531,233

G

endothelin receptor type B

increases expression

Amphotericin B results in increased expression of EDNRB mRNA

NCBI chr13:77,895,481...77,975,527
Ensembl chr13:77,895,481...77,975,529

G

EFR3 homolog B

increases expression

Amphotericin B analog results in increased expression of EFR3B mRNA

NCBI chr 2:25,042,076...25,159,135
Ensembl chr 2:25,042,076...25,159,135

G

egl-9 family hypoxia inducible factor 3

decreases expression

Amphotericin B analog results in decreased expression of EGLN3 mRNA

NCBI chr14:33,924,227...33,951,074
Ensembl chr14:33,924,227...34,462,774

G

empty spiracles homeobox 2

decreases expression

Amphotericin B analog results in decreased expression of EMX2 mRNA

NCBI chr10:117,542,746...117,549,546
Ensembl chr10:117,542,445...117,549,546

G

enolase 1

multiple interactions

Amphotericin B inhibits the reaction [Oxygen deficiency results in increased expression of ENO1 mRNA]; Amphotericin B results in increased expression of and results in increased secretion of ENO1 protein

PMID:16189267 PMID:26259607

NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190

G

ectonucleotide pyrophosphatase/phosphodiesterase 2

decreases expression

Amphotericin B analog results in decreased expression of ENPP2 mRNA

NCBI chr 8:119,557,086...119,673,390
Ensembl chr 8:119,557,086...119,673,453

G

E1A binding protein p300

multiple interactions

Amphotericin B inhibits the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]

NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,592...41,180,077

G

erythropoietin

multiple interactions
decreases expression

Amphotericin B inhibits the reaction [[HIF1A protein binds to ARNT protein] which binds to EPO enhancer]; Amphotericin B inhibits the reaction [Oxygen deficiency results in increased expression of EPO mRNA]
Amphotericin B results in decreased expression of EPO protein

PMID:697352 PMID:2299214 PMID:16189267

NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700

G

erythropoietin receptor

increases expression

Amphotericin B analog results in increased expression of EPOR mRNA; Amphotericin B results in increased expression of EPOR mRNA

NCBI chr19:11,377,207...11,384,314
Ensembl chr19:11,377,207...11,384,342

G

epiregulin

increases expression

Amphotericin B analog results in increased expression of EREG mRNA

NCBI chr 4:74,365,145...74,388,749
Ensembl chr 4:74,365,145...74,388,749

G

family with sequence similarity 13 member A

decreases expression

Amphotericin B analog results in decreased expression of FAM13A mRNA

NCBI chr 4:88,725,960...89,057,185
Ensembl chr 4:88,725,955...89,111,398

G

family with sequence similarity 200 member C

decreases expression

Amphotericin B analog results in decreased expression of ZBED8 mRNA

NCBI chr 5:160,393,148...160,400,054
Ensembl chr 5:160,393,148...160,400,054

G

fatty acid synthase

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of FASN mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of FASN mRNA

NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294

G

fibulin 1

increases expression

Amphotericin B analog results in increased expression of FBLN1 mRNA

NCBI chr22:45,502,883...45,601,135
Ensembl chr22:45,502,238...45,601,135

G

Fc gamma receptor Ia

increases expression

Amphotericin B analog results in increased expression of FCGR1A mRNA

NCBI chr 1:149,782,694...149,800,609
Ensembl chr 1:149,782,671...149,791,675

G

Fc gamma receptor Ic, pseudogene

increases expression

Amphotericin B analog results in increased expression of FCGR1CP mRNA

NCBI chr 1:143,874,743...143,883,733
Ensembl chr 1:143,874,793...143,883,575

G

fibrinogen beta chain

decreases expression

Amphotericin B analog results in decreased expression of FGB mRNA

NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807

G

fibroblast growth factor 4

increases expression

Amphotericin B analog results in increased expression of FGF4 mRNA

NCBI chr11:69,771,022...69,775,341
Ensembl chr11:69,771,022...69,775,341

G

FKBP prolyl isomerase 5

decreases expression

Amphotericin B analog results in decreased expression of FKBP5 mRNA

NCBI chr 6:35,573,590...35,728,583
Ensembl chr 6:35,573,585...35,728,583

G

fibronectin leucine rich transmembrane protein 3

decreases expression

Amphotericin B analog results in decreased expression of FLRT3 mRNA; Amphotericin B results in decreased expression of FLRT3 mRNA

NCBI chr20:14,322,985...14,337,612
Ensembl chr20:14,322,985...14,337,614

G

FosB proto-oncogene, AP-1 transcription factor subunit

increases expression

Amphotericin B analog results in increased expression of FOSB mRNA

NCBI chr19:45,467,996...45,475,179
Ensembl chr19:45,467,995...45,475,179

G

FERM domain containing 4B

decreases expression

Amphotericin B analog results in decreased expression of FRMD4B mRNA

NCBI chr 3:69,168,782...69,542,586
Ensembl chr 3:69,168,782...69,542,583

G

fibrinogen silencer binding protein

decreases expression

Amphotericin B analog results in decreased expression of FSBP mRNA

NCBI chr 8:94,427,716...94,436,944
Ensembl chr 8:94,378,377...94,436,952

G

far upstream element binding protein 1

decreases expression

Amphotericin B analog results in decreased expression of FUBP1 mRNA

NCBI chr 1:77,944,055...77,979,501
Ensembl chr 1:77,944,055...77,979,110

G

FMR1 autosomal homolog 1

decreases expression

Amphotericin B analog results in decreased expression of FXR1 mRNA

NCBI chr 3:180,912,670...180,982,753
Ensembl chr 3:180,868,141...180,982,753

G

FXYD domain containing ion transport regulator 3

increases expression

Amphotericin B analog results in increased expression of FXYD3 mRNA

NCBI chr19:35,115,823...35,124,324
Ensembl chr19:35,115,823...35,124,324

G

galactose-3-O-sulfotransferase 1

decreases expression

Amphotericin B analog results in decreased expression of GAL3ST1 mRNA

NCBI chr22:30,554,635...30,574,665
Ensembl chr22:30,554,635...30,574,665

G

galanin receptor 3

increases expression

Amphotericin B analog results in increased expression of GALR3 mRNA

NCBI chr22:37,823,382...37,825,485
Ensembl chr22:37,823,382...37,825,485

G

growth differentiation factor 15

increases expression

Amphotericin B analog results in increased expression of GDF15 mRNA; Amphotericin B results in increased expression of GDF15 mRNA

NCBI chr19:18,386,158...18,389,176
Ensembl chr19:18,374,731...18,389,176

G

GDNF family receptor alpha 3

increases expression

Amphotericin B analog results in increased expression of GFRA3 mRNA

NCBI chr 5:138,252,380...138,274,621
Ensembl chr 5:138,252,380...138,274,621

G

GDNF family receptor alpha 4

increases expression

Amphotericin B analog results in increased expression of GFRA4 mRNA

NCBI chr20:3,659,248...3,663,399
Ensembl chr20:3,659,248...3,663,399

G

glucuronic acid epimerase

decreases expression

Amphotericin B analog results in decreased expression of GLCE mRNA

NCBI chr15:69,160,635...69,272,207
Ensembl chr15:69,160,584...69,272,217

G

glyoxalase domain containing 4

decreases expression

Amphotericin B results in decreased expression of GLOD4 mRNA

NCBI chr17:759,330...785,895
Ensembl chr17:757,097...782,294

G

glutaminase

increases expression

Amphotericin B analog results in increased expression of GLS mRNA

NCBI chr 2:190,880,821...190,965,552
Ensembl chr 2:190,880,821...190,965,552

G

glutamate-ammonia ligase

decreases expression

Amphotericin B analog results in decreased expression of GLUL mRNA

NCBI chr 1:182,378,098...182,391,790
Ensembl chr 1:182,378,098...182,392,206

G

glycoprotein Ib platelet subunit alpha

increases expression

Amphotericin B analog results in increased expression of GP1BA mRNA

NCBI chr17:4,932,277...4,935,023
Ensembl chr17:4,932,277...4,935,023

G

G protein-coupled receptor 20

increases expression

Amphotericin B results in increased expression of GPR20 mRNA

NCBI chr 8:141,356,470...141,367,286
Ensembl chr 8:141,356,470...141,367,286

G

glutamic--pyruvic transaminase

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased activity of GPT protein]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased activity of GPT protein

NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174

G

glutamate ionotropic receptor delta type subunit 2

increases expression

Amphotericin B analog results in increased expression of GRID2 mRNA

NCBI chr 4:92,303,966...93,810,456
Ensembl chr 4:92,303,966...93,810,157

G

glutamate metabotropic receptor 6

increases expression

Amphotericin B analog results in increased expression of GRM6 mRNA

NCBI chr 5:178,978,327...178,995,320
Ensembl chr 5:178,977,587...178,996,206

G

glutathione S-transferase pi 1

decreases expression
multiple interactions

Amphotericin B results in decreased expression of GSTP1 mRNA
Amphotericin B inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate]

PMID:20623750 PMID:23769903

NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656

G

glutathione S-transferase theta 1

decreases expression

Amphotericin B results in decreased expression of GSTT1 mRNA

G

H2A clustered histone 4

decreases expression

Amphotericin B analog results in decreased expression of HIST1H2AC mRNA

NCBI chr 6:26,033,092...26,033,618
Ensembl chr 6:26,033,092...26,033,618

G

hypoxia inducible factor 1 subunit alpha

multiple interactions
decreases activity

Amphotericin B inhibits the reaction [[HIF1A protein binds to ARNT protein] which binds to EPO enhancer]; Amphotericin B inhibits the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]; Amphotericin B promotes the reaction [HIF1AN protein binds to and results in increased hydroxylation of and results in decreased activity of HIF1A protein]
Amphotericin B results in decreased activity of HIF1A protein

NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259

G

hypoxia inducible factor 1 subunit alpha inhibitor

multiple interactions

Amphotericin B promotes the reaction [HIF1AN protein binds to and results in increased hydroxylation of and results in decreased activity of HIF1A protein]

NCBI chr10:100,535,943...100,559,998
Ensembl chr10:100,529,072...100,559,998

G

hypoxia inducible lipid droplet associated

decreases expression

Amphotericin B analog results in decreased expression of HILPDA mRNA

NCBI chr 7:128,455,878...128,458,418
Ensembl chr 7:128,455,849...128,458,418

G

homeodomain interacting protein kinase 1

decreases expression

Amphotericin B analog results in decreased expression of HIPK1 mRNA

NCBI chr 1:113,929,324...113,977,869
Ensembl chr 1:113,929,324...113,977,869

G

major histocompatibility complex, class I, F

increases expression

Amphotericin B results in increased expression of HLA-F mRNA

NCBI chr 6:29,723,434...29,738,532
Ensembl chr 6:29,722,775...29,738,528

G

3-hydroxy-3-methylglutaryl-CoA reductase

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of HMGCR mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of HMGCR mRNA

NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001

G

heme oxygenase 1

increases expression

Amphotericin B analog results in increased expression of HMOX1 mRNA; Amphotericin B results in increased expression of HMOX1 mRNA

NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214

G

hook microtubule tethering protein 1

decreases expression

Amphotericin B analog results in decreased expression of HOOK1 mRNA

NCBI chr 1:59,814,949...59,876,322
Ensembl chr 1:59,814,786...59,876,322

G

homeobox D3

decreases expression

Amphotericin B analog results in decreased expression of HOXD3 mRNA

NCBI chr 2:176,152,529...176,173,098
Ensembl chr 2:176,136,612...176,173,102

G

homeobox D4

decreases expression

Amphotericin B analog results in decreased expression of HOXD4 mRNA

NCBI chr 2:176,151,550...176,153,226
Ensembl chr 2:176,151,550...176,153,226

G

hemopexin

increases expression

Amphotericin B analog results in increased expression of HPX mRNA

NCBI chr11:6,431,049...6,440,987
Ensembl chr11:6,431,049...6,442,617

G

heat shock protein family A (Hsp70) member 1A

decreases expression

Amphotericin B analog results in decreased expression of HSPA1A mRNA

NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946

G

heat shock protein family A (Hsp70) member 1B

decreases expression

Amphotericin B analog results in decreased expression of HSPA1B mRNA

NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254

G

heat shock protein family A (Hsp70) member 2

decreases expression

Amphotericin B analog results in decreased expression of HSPA2 mRNA

NCBI chr14:64,535,905...64,543,237
Ensembl chr14:64,535,905...64,546,173

G

heat shock protein family A (Hsp70) member 8

multiple interactions

Amphotericin B results in increased expression of and results in increased secretion of HSPA8 protein

NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230

G

heat shock protein family B (small) member 3

increases expression

Amphotericin B analog results in increased expression of HSPB3 mRNA

NCBI chr 5:54,455,699...54,456,377
Ensembl chr 5:54,455,699...54,456,377

G

5-hydroxytryptamine receptor 3A

increases expression

Amphotericin B analog results in increased expression of HTR3A mRNA

NCBI chr11:113,975,108...113,990,313
Ensembl chr11:113,975,075...113,990,313

G

intercellular adhesion molecule 1

increases expression

Amphotericin B analog results in increased expression of ICAM1 mRNA; Amphotericin B results in increased expression of ICAM1 mRNA

NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615

G

inhibitor of DNA binding 2

decreases expression

Amphotericin B analog results in decreased expression of ID2 mRNA

NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461

G

inhibitor of DNA binding 2B (pseudogene)

decreases expression

Amphotericin B analog results in decreased expression of ID2B mRNA

NCBI chr 3:62,123,426...62,124,718

G

inhibitor of DNA binding 4

decreases expression

Amphotericin B analog results in decreased expression of ID4 mRNA; Amphotericin B results in decreased expression of ID4 mRNA

NCBI chr 6:19,837,370...19,842,197
Ensembl chr 6:19,837,370...19,842,197

G

interferon alpha 21

increases expression

Amphotericin B analog results in increased expression of IFNA21 mRNA

NCBI chr 9:21,165,637...21,166,660
Ensembl chr 9:21,165,637...21,166,660

G

interferon gamma

multiple interactions
increases expression

[Amphotericin B co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Antimony Sodium Gluconate co-treated with Amphotericin B] results in increased expression of IFNG protein
Amphotericin B analog results in increased expression of IFNG mRNA

PMID:17911647 PMID:28534445 PMID:29594315

NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740

G

interferon gamma receptor 1

increases expression

Amphotericin B results in increased expression of IFNGR1

NCBI chr 6:137,197,484...137,219,385
Ensembl chr 6:137,197,483...137,219,449

G

insulin like growth factor binding protein 5

decreases expression

Amphotericin B results in decreased expression of IGFBP5 mRNA

NCBI chr 2:216,672,105...216,695,549
Ensembl chr 2:216,672,105...216,695,549

G

interleukin 10

multiple interactions

[Antimony Sodium Gluconate co-treated with Amphotericin B] results in decreased expression of IL10 protein

NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541

G

interleukin 13 receptor subunit alpha 2

increases expression

Amphotericin B analog results in increased expression of IL13RA2 mRNA

NCBI chr X:115,003,982...115,017,616
Ensembl chr X:115,003,975...115,019,977

G

interleukin 1 beta

increases expression

Amphotericin B results in increased expression of IL1B mRNA

NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816

G

interleukin 1 receptor type 2

decreases expression

Amphotericin B analog results in decreased expression of IL1R2 mRNA

NCBI chr 2:101,991,960...102,028,544
Ensembl chr 2:101,991,960...102,028,544

G

interleukin 1 receptor accessory protein like 2

increases expression

Amphotericin B analog results in increased expression of IL1RAPL2 mRNA

NCBI chr X:104,566,199...105,767,829
Ensembl chr X:104,566,199...105,767,829

G

interleukin 2

multiple interactions

[Amphotericin B co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA

NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725

G

interleukin 6

increases expression

Amphotericin B analog results in increased expression of IL6 mRNA

NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002

G

inhibin subunit beta A

increases expression

Amphotericin B analog results in increased expression of INHBA mRNA

NCBI chr 7:41,685,114...41,705,406
Ensembl chr 7:41,667,168...41,705,834

G

INO80 complex subunit B

decreases expression

Amphotericin B analog results in decreased expression of INO80B mRNA

NCBI chr 2:74,455,087...74,457,944
Ensembl chr 2:74,455,087...74,457,944

G

insulin induced gene 1

increases expression

Amphotericin B analog results in increased expression of INSIG1 mRNA; Amphotericin B results in increased expression of INSIG1 mRNA

NCBI chr 7:155,297,878...155,310,235
Ensembl chr 7:155,297,776...155,310,235

G

interferon regulatory factor 5

increases expression

Amphotericin B analog results in increased expression of IRF5 mRNA

NCBI chr 7:128,937,032...128,950,038
Ensembl chr 7:128,937,457...128,950,038

G

jagged canonical Notch ligand 1

decreases expression

Amphotericin B results in decreased expression of JAG1 mRNA

NCBI chr20:10,637,684...10,673,999
Ensembl chr20:10,637,684...10,673,999

G

kazrin, periplakin interacting protein

increases expression

Amphotericin B analog results in increased expression of KAZN mRNA

NCBI chr 1:13,892,824...15,118,043
Ensembl chr 1:13,892,792...15,118,043

G

potassium voltage-gated channel subfamily B member 1

decreases expression

Amphotericin B analog results in decreased expression of KCNB1 mRNA

NCBI chr20:49,363,877...49,483,362
Ensembl chr20:49,293,394...49,484,297

G

potassium voltage-gated channel subfamily Q member 4

decreases expression

Amphotericin B results in decreased expression of KCNQ4 mRNA

NCBI chr 1:40,783,787...40,840,452
Ensembl chr 1:40,783,787...40,840,452

G

KLF transcription factor 12

increases expression

Amphotericin B analog results in increased expression of KLF12 mRNA

NCBI chr13:73,686,089...74,306,045
Ensembl chr13:73,686,089...74,134,404

G

KLF transcription factor 9

decreases expression

Amphotericin B analog results in decreased expression of KLF9 mRNA

NCBI chr 9:70,384,604...70,414,657
Ensembl chr 9:70,384,604...70,414,657

G

kelch like family member 24

decreases expression

Amphotericin B analog results in decreased expression of KLHL24 mRNA

NCBI chr 3:183,635,623...183,684,519
Ensembl chr 3:183,635,610...183,684,519

G

kallikrein related peptidase 2

increases expression

Amphotericin B analog results in increased expression of KLK2 mRNA

NCBI chr19:50,873,439...50,880,567
Ensembl chr19:50,861,568...50,880,567

G

killer cell lectin like receptor B1

increases expression

Amphotericin B analog results in increased expression of KLRB1 mRNA

NCBI chr12:9,594,551...9,607,916
Ensembl chr12:9,594,551...9,607,916

G

kynurenine 3-monooxygenase

decreases expression

Amphotericin B analog results in decreased expression of KMO mRNA

NCBI chr 1:241,532,378...241,595,642
Ensembl chr 1:241,532,134...241,595,642

G

lactalbumin alpha

increases expression

Amphotericin B analog results in increased expression of LALBA mRNA

NCBI chr12:48,567,684...48,571,845
Ensembl chr12:48,567,684...48,570,066

G

lipocalin 2

decreases expression

Amphotericin B analog results in decreased expression of LCN2 mRNA

NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453

G

low density lipoprotein receptor

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA

NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820

G

low density lipoprotein receptor class A domain containing 4

increases expression

Amphotericin B analog results in increased expression of LDLRAD4 mRNA

NCBI chr18:13,217,682...13,652,754
Ensembl chr18:13,217,498...13,652,755

G

galectin 4

increases expression

Amphotericin B analog results in increased expression of LGALS4 mRNA

NCBI chr19:38,801,674...38,812,945
Ensembl chr19:38,801,671...38,812,945

G

LIM domain kinase 1

increases expression

Amphotericin B analog results in increased expression of LIMK1 mRNA

NCBI chr 7:74,083,804...74,122,525
Ensembl chr 7:74,082,933...74,122,525

G

long intergenic non-protein coding RNA 1278

increases expression

Amphotericin B analog results in increased expression of LINC01278 mRNA

NCBI chr X:63,426,558...63,561,095
Ensembl chr X:63,222,993...63,561,095

G

lipin 1

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LPIN1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LPIN1 mRNA

NCBI chr 2:11,677,544...11,827,409
Ensembl chr 2:11,677,595...11,827,409

G

large 60S subunit nuclear export GTPase 1

decreases expression

Amphotericin B results in decreased expression of LSG1 mRNA

NCBI chr 3:194,640,791...194,672,191
Ensembl chr 3:194,640,791...194,672,463

G

lysosomal trafficking regulator

increases expression

Amphotericin B analog results in increased expression of LYST mRNA

NCBI chr 1:235,661,031...235,883,713
Ensembl chr 1:235,661,041...235,883,724

G

mucosal vascular addressin cell adhesion molecule 1

increases expression

Amphotericin B analog results in increased expression of MADCAM1 mRNA

NCBI chr19:496,486...505,343
Ensembl chr19:489,176...505,343

G

MAF bZIP transcription factor

decreases expression

Amphotericin B analog results in decreased expression of MAF mRNA

NCBI chr16:79,202,622...79,600,737
Ensembl chr16:79,585,843...79,600,737

G

monoamine oxidase A

decreases expression

Amphotericin B analog results in decreased expression of MAOA mRNA

NCBI chr X:43,655,006...43,746,817
Ensembl chr X:43,654,907...43,746,817

G

microtubule associated protein 1 light chain 3 beta

increases expression

Amphotericin B results in increased expression of MAP1LC3B protein

NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779

G

mitogen-activated protein kinase kinase kinase 19

increases expression

Amphotericin B analog results in increased expression of MAP3K19 mRNA

NCBI chr 2:134,964,491...135,047,447
Ensembl chr 2:134,964,485...135,047,468

G

minichromosome maintenance complex component 3 associated protein

increases expression

Amphotericin B analog results in increased expression of MCM3AP mRNA

NCBI chr21:46,235,133...46,286,265
Ensembl chr21:46,235,133...46,286,297

G

MTOR associated protein, eak-7 homolog

increases expression

Amphotericin B analog results in increased expression of TLDC1 mRNA

NCBI chr16:84,476,355...84,504,659
Ensembl chr16:84,476,355...84,554,033

G

myocyte enhancer factor 2C

decreases expression

Amphotericin B analog results in decreased expression of MEF2C mRNA

NCBI chr 5:88,717,117...88,904,105
Ensembl chr 5:88,717,117...88,904,257

G

microRNA 106b

increases expression

Amphotericin B analog results in increased expression of MIR106B

NCBI chr 7:100,093,993...100,094,074
Ensembl chr 7:100,093,993...100,094,074

G

microRNA 1180

increases expression

Amphotericin B analog results in increased expression of MIR1180

NCBI chr17:19,344,506...19,344,574
Ensembl chr17:19,344,506...19,344,574

G

microRNA 1268a

increases expression

Amphotericin B results in increased expression of MIR1268A

NCBI chr15:22,225,278...22,225,329
Ensembl chr15:22,225,278...22,225,329

G

microRNA 1275

increases expression

Amphotericin B results in increased expression of MIR1275

NCBI chr 6:33,999,972...34,000,051
Ensembl chr 6:33,999,972...34,000,051

G

microRNA 138-1

increases expression

Amphotericin B results in increased expression of MIR138

NCBI chr 3:44,114,212...44,114,310
Ensembl chr 3:44,114,212...44,114,310

G

microRNA 17

increases expression

Amphotericin B analog results in increased expression of MIR17

NCBI chr13:91,350,605...91,350,688
Ensembl chr13:91,350,605...91,350,688

G

microRNA 181c

increases expression

Amphotericin B analog results in increased expression of MIR181C

NCBI chr19:13,874,699...13,874,808
Ensembl chr19:13,874,699...13,874,808

G

microRNA 181d

decreases expression

Amphotericin B analog results in decreased expression of MIR181D

NCBI chr19:13,874,875...13,875,011
Ensembl chr19:13,874,875...13,875,011

G

microRNA 2277

increases expression

Amphotericin B results in increased expression of MIR2277

NCBI chr 5:93,620,696...93,620,788
Ensembl chr 5:93,620,696...93,620,788

G

microRNA 3141

decreases expression

Amphotericin B analog results in decreased expression of MIR3141

NCBI chr 5:154,596,012...154,596,072
Ensembl chr 5:154,596,012...154,596,072

G

microRNA 3153

decreases expression

Amphotericin B results in decreased expression of MIR3153

NCBI chr 9:89,312,225...89,312,306
Ensembl chr 9:89,312,225...89,312,306

G

microRNA 3197

decreases expression

Amphotericin B analog results in decreased expression of MIR3197; Amphotericin B results in decreased expression of MIR3197

NCBI chr21:41,167,557...41,167,629
Ensembl chr21:41,167,557...41,167,629

G

microRNA 320c-2

increases expression

Amphotericin B analog results in increased expression of MIR320C2

NCBI chr18:24,321,675...24,321,746
Ensembl chr18:24,321,686...24,321,735

G

microRNA 320e

increases expression

Amphotericin B analog results in increased expression of MIR320E

NCBI chr19:46,709,282...46,709,354
Ensembl chr19:46,709,293...46,709,345

G

microRNA 421

increases expression

Amphotericin B analog results in increased expression of MIR421

NCBI chr X:74,218,377...74,218,461
Ensembl chr X:74,218,377...74,218,461

G

microRNA 423

increases expression

Amphotericin B analog results in increased expression of MIR423; Amphotericin B results in increased expression of MIR423

NCBI chr17:30,117,079...30,117,172
Ensembl chr17:30,117,079...30,117,172

G

microRNA 4298

decreases expression

Amphotericin B analog results in decreased expression of MIR4298; Amphotericin B results in decreased expression of MIR4298

NCBI chr11:1,859,464...1,859,536
Ensembl chr11:1,859,464...1,859,536

G

microRNA 494

decreases expression

Amphotericin B analog results in decreased expression of MIR494; Amphotericin B results in decreased expression of MIR494

NCBI chr14:101,029,634...101,029,714
Ensembl chr14:101,029,634...101,029,714

G

microRNA 885

decreases expression

Amphotericin B analog results in decreased expression of MIR885

NCBI chr 3:10,394,489...10,394,562
Ensembl chr 3:10,394,489...10,394,562

G

microRNA 99b

increases expression

Amphotericin B analog results in increased expression of MIR99B

NCBI chr19:51,692,612...51,692,681
Ensembl chr19:51,692,612...51,692,681

G

microRNA let-7g

decreases expression

Amphotericin B analog results in decreased expression of MIRLET7G

NCBI chr 3:52,268,278...52,268,361
Ensembl chr 3:52,268,278...52,268,361

G

matrix metallopeptidase 28

decreases expression

Amphotericin B analog results in decreased expression of MMP28 mRNA

NCBI chr17:35,756,249...35,795,641
Ensembl chr17:35,756,249...35,795,707

G

M-phase phosphoprotein 8

decreases expression

Amphotericin B analog results in decreased expression of MPHOSPH8 mRNA

NCBI chr13:19,633,659...19,673,441
Ensembl chr13:19,633,659...19,673,441

G

metal response element binding transcription factor 2

decreases expression

Amphotericin B analog results in decreased expression of MTF2 mRNA

NCBI chr 1:93,079,283...93,139,076
Ensembl chr 1:93,079,235...93,139,079

G

mucin 2, oligomeric mucus/gel-forming

increases expression

Amphotericin B analog results in increased expression of MUC2 mRNA

NCBI chr11:1,074,874...1,110,508
Ensembl chr11:1,074,875...1,110,511

G

MX dynamin like GTPase 2

increases expression

Amphotericin B analog results in increased expression of MX2 mRNA

NCBI chr21:41,362,027...41,409,393
Ensembl chr21:41,361,999...41,409,393

G

myosin XVB

increases expression

Amphotericin B analog results in increased expression of MYO15B mRNA

NCBI chr17:75,587,800...75,626,849
Ensembl chr17:75,587,800...75,626,849

G

myosin VIIA

increases expression

Amphotericin B analog results in increased expression of MYO7A mRNA

NCBI chr11:77,128,246...77,215,241
Ensembl chr11:77,128,246...77,215,241

G

N-acetyltransferase 8 (putative)

decreases expression

Amphotericin B analog results in decreased expression of NAT8 mRNA

NCBI chr 2:73,640,723...73,642,422
Ensembl chr 2:73,640,723...73,642,422

G

neural precursor cell expressed, developmentally down-regulated 9

decreases expression

Amphotericin B analog results in decreased expression of NEDD9 mRNA

NCBI chr 6:11,183,298...11,382,348
Ensembl chr 6:11,183,298...11,382,348

G

neurofilament light chain

decreases expression

Amphotericin B analog results in decreased expression of NEFL mRNA

NCBI chr 8:24,950,955...24,956,612
Ensembl chr 8:24,950,955...24,956,721

G

neurofilament medium chain

decreases expression

Amphotericin B analog results in decreased expression of NEFM mRNA

NCBI chr 8:24,913,761...24,919,093
Ensembl chr 8:24,913,758...24,919,098

G

NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor

decreases expression

Amphotericin B analog results in decreased expression of NF2 mRNA

NCBI chr22:29,603,556...29,698,600
Ensembl chr22:29,603,556...29,698,598

G

nucleolar protein 3

decreases expression

Amphotericin B analog results in decreased expression of NOL3 mRNA

NCBI chr16:67,170,538...67,175,737
Ensembl chr16:67,170,154...67,175,737

G

NPR2 like, GATOR1 complex subunit

decreases expression

Amphotericin B results in decreased expression of NPRL2 mRNA

NCBI chr 3:50,347,330...50,350,775
Ensembl chr 3:50,347,330...50,350,826

G

nuclear receptor subfamily 2 group E member 1

increases expression

Amphotericin B analog results in increased expression of NR2E1 mRNA

NCBI chr 6:108,166,022...108,188,809
Ensembl chr 6:108,166,022...108,188,805

G

nuclear receptor subfamily 2 group F member 1

decreases expression

Amphotericin B analog results in decreased expression of NR2F1 mRNA

NCBI chr 5:93,583,222...93,594,611
Ensembl chr 5:93,583,222...93,594,611

G

5'-nucleotidase, cytosolic II

increases expression

Amphotericin B results in increased expression of NT5C2 mRNA

NCBI chr10:103,088,017...103,193,272
Ensembl chr10:103,087,185...103,277,605

G

neurotrophic receptor tyrosine kinase 2

decreases expression
increases expression

Amphotericin B analog results in decreased expression of NTRK2 mRNA
Amphotericin B analog results in increased expression of NTRK2 mRNA

NCBI chr 9:84,668,522...85,027,054
Ensembl chr 9:84,668,375...85,095,751

G

olfactory receptor family 10 subfamily J member 1

increases expression

Amphotericin B analog results in increased expression of OR10J1 mRNA

NCBI chr 1:159,397,465...159,440,967
Ensembl chr 1:159,437,845...159,443,078

G

olfactory receptor family 2 subfamily H member 2

increases expression

Amphotericin B analog results in increased expression of OR2H2 mRNA

NCBI chr 6:29,585,121...29,590,500
Ensembl chr 6:29,585,121...29,590,500

G

ovo like zinc finger 2

increases expression

Amphotericin B analog results in increased expression of OVOL2 mRNA

NCBI chr20:18,024,152...18,059,188
Ensembl chr20:17,956,979...18,059,188

G

poly(A) binding protein interacting protein 1

decreases expression

Amphotericin B results in decreased expression of PAIP1 mRNA

NCBI chr 5:43,526,267...43,557,411
Ensembl chr 5:43,526,267...43,557,758

G

par-3 family cell polarity regulator

decreases expression

Amphotericin B results in decreased expression of PARD3 mRNA

NCBI chr10:34,109,561...34,815,296
Ensembl chr10:34,109,560...34,815,325

G

par-6 family cell polarity regulator beta

increases expression

Amphotericin B analog results in increased expression of PARD6B mRNA

NCBI chr20:50,731,580...50,753,741
Ensembl chr20:50,731,580...50,756,795

G

prostate androgen-regulated transcript 1

increases expression

Amphotericin B results in increased expression of PART1 mRNA

NCBI chr 5:60,487,713...60,547,657
Ensembl chr 5:60,487,713...60,548,813

G

phosphodiesterase 1A

decreases expression

Amphotericin B analog results in decreased expression of PDE1A mRNA

NCBI chr 2:182,140,041...182,716,797
Ensembl chr 2:182,139,968...182,523,359

G

phosphodiesterase 4D

decreases expression

Amphotericin B analog results in decreased expression of PDE4D mRNA

NCBI chr 5:58,969,038...60,522,128
Ensembl chr 5:58,969,038...60,522,120

G

phosphodiesterase 4D interacting protein

decreases expression

Amphotericin B analog results in decreased expression of PDE4DIP mRNA

NCBI chr 1:148,808,434...149,033,016
Ensembl chr 1:148,808,140...149,048,286

G

PDZ and LIM domain 7

decreases expression

Amphotericin B analog results in decreased expression of PDLIM7 mRNA

NCBI chr 5:177,483,394...177,497,604
Ensembl chr 5:177,483,394...177,497,606

G

platelet and endothelial cell adhesion molecule 1

increases expression

Amphotericin B analog results in increased expression of PECAM1 mRNA

NCBI chr17:64,319,415...64,390,860
Ensembl chr17:64,319,415...64,413,776

G

phosphoglycerate kinase 1

multiple interactions

Amphotericin B inhibits the reaction [Oxygen deficiency results in increased expression of PGK1 mRNA]

NCBI chr X:78,104,248...78,129,295
Ensembl chr X:77,910,739...78,129,295

G

phosphoinositide-3-kinase regulatory subunit 1

decreases expression

Amphotericin B analog results in decreased expression of PIK3R1 mRNA

NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821

G

paired like homeodomain 2

decreases expression

Amphotericin B analog results in decreased expression of PITX2 mRNA; Amphotericin B results in decreased expression of PITX2 mRNA

NCBI chr 4:110,617,423...110,642,123
Ensembl chr 4:110,617,423...110,642,123

G

pyruvate kinase L/R

increases expression

Amphotericin B analog results in increased expression of PKLR mRNA

NCBI chr 1:155,289,293...155,308,654
Ensembl chr 1:155,289,293...155,301,438

G

plakophilin 1

increases expression

Amphotericin B analog results in increased expression of PKP1 mRNA

NCBI chr 1:201,283,506...201,332,989
Ensembl chr 1:201,283,452...201,332,993

G

phospholipase A2 group IIA

increases expression

Amphotericin B analog results in increased expression of PLA2G2A mRNA

NCBI chr 1:19,975,431...19,980,434
Ensembl chr 1:19,975,431...19,980,416

G

phospholipase C beta 1

increases expression

Amphotericin B analog results in increased expression of PLCB1 mRNA

NCBI chr20:8,132,266...8,884,900
Ensembl chr20:8,077,251...8,968,360

G

phorbol-12-myristate-13-acetate-induced protein 1

increases expression

Amphotericin B analog results in increased expression of PMAIP1 mRNA

NCBI chr18:59,899,996...59,904,305
Ensembl chr18:59,899,996...59,904,305

G

DNA polymerase gamma, catalytic subunit

increases expression

Amphotericin B analog results in increased expression of POLG mRNA; Amphotericin B results in increased expression of POLG mRNA

NCBI chr15:89,316,320...89,334,824
Ensembl chr15:89,305,198...89,334,861

G

DNA polymerase mu

increases expression

Amphotericin B results in increased expression of POLM mRNA

NCBI chr 7:44,072,062...44,082,530
Ensembl chr 7:44,072,062...44,082,530

G

periplakin

decreases expression

Amphotericin B analog results in decreased expression of PPL mRNA

NCBI chr16:4,882,507...4,937,148
Ensembl chr16:4,882,507...4,960,741

G

protein phosphatase 1 regulatory subunit 3C

decreases expression

Amphotericin B analog results in decreased expression of PPP1R3C mRNA

NCBI chr10:91,628,442...91,633,071
Ensembl chr10:91,628,442...91,633,071

G

phosphoserine aminotransferase 1

decreases expression

Amphotericin B analog results in decreased expression of PSAT1 mRNA

NCBI chr 9:78,297,125...78,330,093
Ensembl chr 9:78,297,125...78,330,093

G

pregnancy specific beta-1-glycoprotein 11

increases expression

Amphotericin B analog results in increased expression of PSG11 mRNA

NCBI chr19:43,007,656...43,026,469
Ensembl chr19:43,007,656...43,026,474

G

protein tyrosine phosphatase non-receptor type 22

decreases expression

Amphotericin B analog results in decreased expression of PTPN22 mRNA

NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753

G

protein tyrosine phosphatase receptor type T

increases expression

Amphotericin B analog results in increased expression of PTPRT mRNA

NCBI chr20:42,031,890...43,189,906
Ensembl chr20:42,072,752...43,189,970

G

RAD54 homolog B

increases expression

Amphotericin B analog results in increased expression of RAD54B mRNA

NCBI chr 8:94,371,960...94,475,115
Ensembl chr 8:94,371,960...94,475,115

G

receptor activity modifying protein 3

increases expression

Amphotericin B analog results in increased expression of RAMP3 mRNA

NCBI chr 7:45,157,791...45,184,250
Ensembl chr 7:45,157,791...45,186,302

G

retinoic acid receptor responder 1

decreases expression

Amphotericin B analog results in decreased expression of RARRES1 mRNA

NCBI chr 3:158,696,892...158,732,457
Ensembl chr 3:158,696,892...158,732,489

G

RAS guanyl releasing protein 1

decreases expression

Amphotericin B analog results in decreased expression of RASGRP1 mRNA

NCBI chr15:38,488,103...38,564,814
Ensembl chr15:38,488,103...38,565,575

G

RB binding protein 5, histone lysine methyltransferase complex subunit

decreases expression

Amphotericin B analog results in decreased expression of RBBP5 mRNA; Amphotericin B results in decreased expression of RBBP5 mRNA

NCBI chr 1:205,086,142...205,121,978
Ensembl chr 1:205,086,142...205,122,015

G

RNA binding motif protein 47

decreases expression

Amphotericin B analog results in decreased expression of RBM47 mRNA

NCBI chr 4:40,423,280...40,630,852
Ensembl chr 4:40,423,267...40,630,875

G

regulator of calcineurin 2

decreases expression

Amphotericin B analog results in decreased expression of RCAN2 mRNA

NCBI chr 6:46,220,736...46,491,970
Ensembl chr 6:46,220,736...46,491,972

G

REL proto-oncogene, NF-kB subunit

decreases expression

Amphotericin B analog results in decreased expression of REL mRNA

NCBI chr 2:60,881,574...60,931,612
Ensembl chr 2:60,881,491...60,931,612

G

RALBP1 associated Eps domain containing 2

decreases expression

Amphotericin B analog results in decreased expression of REPS2 mRNA

NCBI chr X:16,946,658...17,196,655
Ensembl chr X:16,946,658...17,153,272

G

regulator of G protein signaling 2

decreases expression

Amphotericin B analog results in decreased expression of RGS2 mRNA; Amphotericin B results in decreased expression of RGS2 mRNA

NCBI chr 1:192,809,039...192,812,275
Ensembl chr 1:192,809,039...192,812,275

G

Rh blood group D antigen

increases expression

Amphotericin B analog results in increased expression of RHD mRNA

NCBI chr 1:25,272,486...25,330,445
Ensembl chr 1:25,272,393...25,330,445

G

RHO family interacting cell polarization regulator 2

decreases expression

Amphotericin B analog results in decreased expression of FAM65B mRNA; Amphotericin B results in decreased expression of FAM65B mRNA

NCBI chr 6:24,804,284...25,042,168
Ensembl chr 6:24,804,282...25,042,170

G

required for meiotic nuclear division 5 homolog A

decreases expression

Amphotericin B analog results in decreased expression of RMND5A mRNA

NCBI chr 2:86,720,291...86,778,041
Ensembl chr 2:86,720,291...86,778,041

G

ribonuclease A family member 4

decreases expression

Amphotericin B analog results in decreased expression of RNASE4 mRNA

NCBI chr14:20,684,560...20,701,216
Ensembl chr14:20,684,560...20,701,216

G

Rho family GTPase 3

increases expression

Amphotericin B results in increased expression of RND3 mRNA

NCBI chr 2:150,468,193...150,487,695
Ensembl chr 2:150,468,195...150,539,011

G

RAR related orphan receptor A

decreases expression

Amphotericin B analog results in decreased expression of RORA mRNA

NCBI chr15:60,488,284...61,229,302
Ensembl chr15:60,488,284...61,229,302

G

ribosomal protein S10 pseudogene 2

increases expression

Amphotericin B analog results in increased expression of RPS10P2 mRNA

NCBI chr20:14,757,533...14,758,108
Ensembl chr20:14,757,563...14,758,056

G

ribosomal protein S8

increases expression

Amphotericin B analog results in increased expression of RPS8 mRNA

NCBI chr 1:44,775,540...44,778,779
Ensembl chr 1:44,775,251...44,778,779

G

RRAD, Ras related glycolysis inhibitor and calcium channel regulator

decreases expression

Amphotericin B analog results in decreased expression of RRAD mRNA

NCBI chr16:66,921,685...66,925,535
Ensembl chr16:66,921,685...66,925,535

G

ribosomal L1 domain containing 1

decreases expression

Amphotericin B analog results in decreased expression of RSL1D1 mRNA

NCBI chr16:11,833,850...11,851,542
Ensembl chr16:11,833,850...11,851,580

G

reticulon 1

decreases expression

Amphotericin B analog results in decreased expression of RTN1 mRNA

NCBI chr14:59,595,976...59,870,776
Ensembl chr14:59,595,976...59,870,776

G

RUNX family transcription factor 3

decreases expression

Amphotericin B results in decreased expression of RUNX3 mRNA

NCBI chr 1:24,899,511...24,965,138
Ensembl chr 1:24,899,511...24,965,121

G

Sin3A associated protein 30

increases expression

Amphotericin B analog results in increased expression of SAP30 mRNA

NCBI chr 4:173,370,954...173,377,532
Ensembl chr 4:173,369,969...173,377,532

G

sodium channel epithelial 1 subunit alpha

decreases expression

Amphotericin B analog results in decreased expression of SCNN1A mRNA

NCBI chr12:6,346,847...6,377,359
Ensembl chr12:6,346,843...6,377,730

G

serpin family A member 5

decreases expression

Amphotericin B analog results in decreased expression of SERPINA5 mRNA

NCBI chr14:94,581,426...94,593,118
Ensembl chr14:94,561,442...94,593,118

G

serpin family B member 4

decreases expression

Amphotericin B analog results in decreased expression of SERPINB4 mRNA

NCBI chr18:63,637,259...63,644,256
Ensembl chr18:63,637,259...63,644,256

G

serum/glucocorticoid regulated kinase family member 3

decreases expression

Amphotericin B results in decreased expression of SGK3 mRNA

NCBI chr 8:66,712,781...66,862,022
Ensembl chr 8:66,712,734...66,862,022

G

sialic acid binding Ig like lectin 1

increases expression

Amphotericin B analog results in increased expression of SIGLEC1 mRNA

NCBI chr20:3,686,970...3,712,600
Ensembl chr20:3,686,970...3,712,600

G

salt inducible kinase 1

increases expression

Amphotericin B analog results in increased expression of SIK1 mRNA; Amphotericin B results in increased expression of SIK1 mRNA

NCBI chr21:43,414,483...43,427,131
Ensembl chr21:43,414,483...43,427,131

G

solute carrier family 16 member 6

increases expression

Amphotericin B analog results in increased expression of SLC16A6 mRNA

NCBI chr17:68,267,026...68,291,479
Ensembl chr17:68,267,026...68,291,267

G

solute carrier family 22 member 14

increases expression

Amphotericin B analog results in increased expression of SLC22A14 mRNA

NCBI chr 3:38,278,832...38,318,575
Ensembl chr 3:38,282,294...38,318,575

G

solute carrier family 22 member 7

multiple interactions

[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SLC22A7 mRNA

NCBI chr 6:43,295,714...43,305,538
Ensembl chr 6:43,295,694...43,305,538

G

solute carrier family 27 member 2

decreases expression

Amphotericin B analog results in decreased expression of SLC27A2 mRNA

NCBI chr15:50,182,196...50,236,385
Ensembl chr15:50,182,196...50,236,385

G

solute carrier family 2 member 5

decreases expression

Amphotericin B analog results in decreased expression of SLC2A5 mRNA

NCBI chr 1:9,035,106...9,094,195
Ensembl chr 1:9,035,106...9,088,478

G

solute carrier family 39 member 7

decreases expression

Amphotericin B analog results in decreased expression of SLC39A7 mRNA

NCBI chr 6:33,200,867...33,204,437
Ensembl chr 6:33,200,305...33,204,439

G

solute carrier family 5 member 1

increases expression

Amphotericin B analog results in increased expression of SLC5A1 mRNA

NCBI chr22:32,043,261...32,113,029
Ensembl chr22:32,043,261...32,113,029

G

solute carrier family 6 member 6

decreases expression

Amphotericin B analog results in decreased expression of SLC6A6 mRNA

NCBI chr 3:14,402,576...14,489,349
Ensembl chr 3:14,402,576...14,489,349

G

slit guidance ligand 1

decreases expression

Amphotericin B results in decreased expression of SLIT1 mRNA

NCBI chr10:96,998,038...97,185,959
Ensembl chr10:96,998,038...97,185,959

G

sorbin and SH3 domain containing 1

decreases expression

Amphotericin B analog results in decreased expression of SORBS1 mRNA

NCBI chr10:95,311,773...95,561,371
Ensembl chr10:95,311,771...95,561,414

G

sortilin related receptor 1

decreases expression

Amphotericin B analog results in decreased expression of SORL1 mRNA

NCBI chr11:121,452,314...121,633,763
Ensembl chr11:121,452,314...121,633,763

G

sperm associated antigen 8

decreases expression

Amphotericin B analog results in decreased expression of SPAG8 mRNA

NCBI chr 9:35,807,785...35,812,262
Ensembl chr 9:35,808,045...35,812,272

G

secreted phosphoprotein 1

affects expression

Amphotericin B affects the expression of SPP1 mRNA

NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532

G

sprouty RTK signaling antagonist 1

decreases expression

Amphotericin B analog results in decreased expression of SPRY1 mRNA

NCBI chr 4:123,396,795...123,403,760
Ensembl chr 4:123,396,795...123,403,760

G

spectrin beta, non-erythrocytic 5

increases expression

Amphotericin B analog results in increased expression of SPTBN5 mRNA

NCBI chr15:41,848,146...41,894,053
Ensembl chr15:41,848,146...41,894,053

G

squalene epoxidase

multiple interactions

[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SQLE mRNA

NCBI chr 8:124,998,505...125,022,283
Ensembl chr 8:124,998,497...125,022,283

G

sterol regulatory element binding transcription factor 1

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA

NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002

G

sterol regulatory element binding transcription factor 2

multiple interactions

[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF2 mRNA

NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,105...41,907,306

G

stanniocalcin 1

decreases expression

Amphotericin B analog results in decreased expression of STC1 mRNA

NCBI chr 8:23,841,929...23,854,806
Ensembl chr 8:23,841,929...23,854,806

G

stathmin 4

increases expression

Amphotericin B analog results in increased expression of STMN4 mRNA

NCBI chr 8:27,235,308...27,258,404
Ensembl chr 8:27,235,308...27,258,420

G

tachykinin precursor 3

increases expression

Amphotericin B analog results in increased expression of TAC3 mRNA

NCBI chr12:57,010,000...57,016,529
Ensembl chr12:57,010,000...57,028,883

G

tumor associated calcium signal transducer 2

decreases expression

Amphotericin B analog results in decreased expression of TACSTD2 mRNA

NCBI chr 1:58,575,433...58,577,252
Ensembl chr 1:58,575,433...58,577,252

G

TATA-box binding protein associated factor 13

decreases expression

Amphotericin B analog results in decreased expression of TAF13 mRNA

NCBI chr 1:109,064,140...109,076,003
Ensembl chr 1:109,062,496...109,076,012

G

TAL bHLH transcription factor 1, erythroid differentiation factor

increases expression

Amphotericin B analog results in increased expression of TAL1 mRNA

NCBI chr 1:47,216,290...47,232,335
Ensembl chr 1:47,216,290...47,232,225

G

transcription factor 20

increases expression

Amphotericin B analog results in increased expression of TCF20 mRNA

NCBI chr22:42,160,013...42,343,537
Ensembl chr22:42,160,013...42,343,616

G

transcobalamin 1

decreases expression

Amphotericin B analog results in decreased expression of TCN1 mRNA

NCBI chr11:59,852,808...59,866,487
Ensembl chr11:59,852,800...59,866,489

G

teneurin transmembrane protein 1

decreases expression

Amphotericin B analog results in decreased expression of TENM1 mRNA

NCBI chr X:124,375,903...125,204,312
Ensembl chr X:124,375,903...125,204,312

G

terminal nucleotidyltransferase 5A

decreases expression

Amphotericin B analog results in decreased expression of FAM46A mRNA

NCBI chr 6:81,745,730...81,752,681
Ensembl chr 6:81,491,439...81,752,774

G

transcription factor Dp-2

decreases expression

Amphotericin B analog results in decreased expression of TFDP2 mRNA; Amphotericin B results in decreased expression of TFDP2 mRNA

NCBI chr 3:141,944,428...142,149,544
Ensembl chr 3:141,944,428...142,149,544

G

transcription factor EC

decreases expression

Amphotericin B analog results in decreased expression of TFEC mRNA

NCBI chr 7:115,935,152...116,159,896
Ensembl chr 7:115,935,148...116,159,896

G

trefoil factor 1

increases expression

Amphotericin B analog results in increased expression of TFF1 mRNA

NCBI chr21:42,362,282...42,366,535
Ensembl chr21:42,362,282...42,366,535

G

transforming growth factor beta 1

multiple interactions

[Antimony Sodium Gluconate co-treated with Amphotericin B] results in decreased expression of TGFB1 protein

NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922

G

thymocyte selection associated family member 2

decreases expression

Amphotericin B analog results in decreased expression of THEMIS2 mRNA

NCBI chr 1:27,872,544...27,886,675
Ensembl chr 1:27,872,543...27,886,685

G

transmembrane and coiled-coil domain family 1

decreases expression

Amphotericin B analog results in decreased expression of TMCC1 mRNA

NCBI chr 3:129,647,792...129,893,711
Ensembl chr 3:129,647,792...129,893,711

G

transmembrane protein 140

decreases expression

Amphotericin B analog results in decreased expression of TMEM140 mRNA

NCBI chr 7:135,148,072...135,166,215
Ensembl chr 7:135,148,072...135,166,215

G

transmembrane protein 151B

increases expression

Amphotericin B results in increased expression of TMEM151B mRNA

NCBI chr 6:44,270,450...44,279,444
Ensembl chr 6:44,270,450...44,307,506

G

transmembrane protein 176B

decreases expression

Amphotericin B analog results in decreased expression of TMEM176B mRNA

NCBI chr 7:150,791,301...150,801,360
Ensembl chr 7:150,791,285...150,801,360

G

transmembrane protein 255A

decreases expression

Amphotericin B analog results in decreased expression of TMEM255A mRNA

NCBI chr X:120,251,433...120,311,461
Ensembl chr X:120,258,650...120,311,556

G

transmembrane protein 45A

decreases expression

Amphotericin B analog results in decreased expression of TMEM45A mRNA

NCBI chr 3:100,492,619...100,577,444
Ensembl chr 3:100,492,619...100,577,444

G

transmembrane serine protease 2

increases expression

Amphotericin B results in increased expression of TMPRSS2 mRNA

NCBI chr21:41,464,305...41,508,158
Ensembl chr21:41,464,300...41,531,116

G

tumor necrosis factor

increases expression

Amphotericin B results in increased expression of TNF mRNA

NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336

G

TNF alpha induced protein 3

increases expression

Amphotericin B analog results in increased expression of TNFAIP3 mRNA

NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314

G

TNF superfamily member 4

decreases expression

Amphotericin B analog results in decreased expression of TNFSF4 mRNA

NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,183,731...173,207,331

G

TOX high mobility group box family member 3

decreases expression

Amphotericin B analog results in decreased expression of TOX3 mRNA

NCBI chr16:52,436,416...52,547,802
Ensembl chr16:52,436,417...52,547,802

G

tumor protein p63

increases expression

Amphotericin B analog results in increased expression of TP63 mRNA

NCBI chr 3:189,596,746...189,897,276
Ensembl chr 3:189,631,389...189,897,276

G

T cell receptor alpha variable 10

increases expression

Amphotericin B analog results in increased expression of TRAV10 mRNA

NCBI chr14:21,825,508...21,826,075
Ensembl chr14:21,825,472...21,826,075

G

triggering receptor expressed on myeloid cells 1

decreases expression

Amphotericin B analog results in decreased expression of TREM1 mRNA

NCBI chr 6:41,267,385...41,286,682
Ensembl chr 6:41,267,926...41,286,682

G

transient receptor potential cation channel subfamily M member 3

decreases expression

Amphotericin B analog results in decreased expression of TRPM3 mRNA

NCBI chr 9:70,529,060...71,446,971
Ensembl chr 9:70,529,060...71,446,904

G

transient receptor potential cation channel subfamily M member 6

increases expression

Amphotericin B analog results in increased expression of TRPM6 mRNA

NCBI chr 9:74,722,495...74,887,921
Ensembl chr 9:74,722,495...74,888,094

G

transcriptional repressor GATA binding 1

decreases expression

Amphotericin B analog results in decreased expression of TRPS1 mRNA

NCBI chr 8:115,408,496...115,668,975
Ensembl chr 8:115,408,496...115,809,673

G

testis specific serine kinase 2

increases expression

Amphotericin B analog results in increased expression of TSSK2 mRNA

NCBI chr22:19,131,308...19,132,622
Ensembl chr22:19,131,308...19,132,622

G

testis expressed transcript, Y-linked 2

increases expression

Amphotericin B analog results in increased expression of TTTY2 mRNA

NCBI chr Y:9,736,286...9,758,476
Ensembl chr Y:9,740,584...9,758,476

G

testis expressed transcript, Y-linked 2B

increases expression

Amphotericin B analog results in increased expression of TTTY2B mRNA

NCBI chr Y:6,406,244...6,428,444
Ensembl chr Y:6,406,244...6,462,091

G

thioredoxin interacting protein

decreases expression

Amphotericin B analog results in decreased expression of TXNIP mRNA

NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579

G

ubiquitin conjugating enzyme E2 D4 (putative)

increases expression

Amphotericin B analog results in increased expression of UBE2D4 mRNA

NCBI chr 7:43,926,436...43,956,136
Ensembl chr 7:43,926,436...43,956,136

G

UDP glucuronosyltransferase family 1 member A9

affects expression

Amphotericin B affects the expression of UGT1A9 mRNA

NCBI chr 2:233,671,898...233,773,300
Ensembl chr 2:233,671,898...233,773,300

G

ubiquitin specific peptidase 2

increases expression

Amphotericin B analog results in increased expression of USP2 mRNA

NCBI chr11:119,355,215...119,381,690
Ensembl chr11:119,355,215...119,381,711

G

ubiquitin specific peptidase 36

increases expression

Amphotericin B results in increased expression of USP36 mRNA

NCBI chr17:78,787,381...78,841,439
Ensembl chr17:78,787,381...78,841,441

G

vav guanine nucleotide exchange factor 3

decreases expression

Amphotericin B analog results in decreased expression of VAV3 mRNA; Amphotericin B results in decreased expression of VAV3 mRNA

NCBI chr 1:107,571,161...107,965,180
Ensembl chr 1:107,571,161...107,965,180

G

vestigial like family member 1

increases expression

Amphotericin B analog results in increased expression of VGLL1 mRNA

NCBI chr X:136,532,215...136,556,799
Ensembl chr X:136,532,215...136,556,807

G

vanin 1

decreases expression

Amphotericin B analog results in decreased expression of VNN1 mRNA

NCBI chr 6:132,680,849...132,714,055
Ensembl chr 6:132,680,849...132,714,055

G

X-prolyl aminopeptidase 2

increases expression

Amphotericin B analog results in increased expression of XPNPEP2 mRNA

NCBI chr X:129,738,979...129,769,536
Ensembl chr X:129,738,949...129,769,536

G

zinc finger BED-type containing 2

decreases expression

Amphotericin B results in decreased expression of ZBED2 mRNA

NCBI chr 3:111,592,900...111,595,346
Ensembl chr 3:111,592,900...111,595,346

G

zinc finger and BTB domain containing 16

decreases expression

Amphotericin B analog results in decreased expression of ZBTB16 mRNA

NCBI chr11:114,059,711...114,256,770
Ensembl chr11:114,059,041...114,256,765

G

ZFP36 ring finger protein like 2

decreases expression

Amphotericin B analog results in decreased expression of ZFP36L2 mRNA

NCBI chr 2:43,222,402...43,226,606
Ensembl chr 2:43,222,402...43,226,606

G

zinc finger protein X-linked

decreases expression

Amphotericin B results in decreased expression of ZFX mRNA

NCBI chr X:24,148,982...24,216,255
Ensembl chr X:24,149,173...24,216,255

G

zinc finger protein Y-linked

decreases expression

Amphotericin B results in decreased expression of ZFY mRNA

NCBI chr Y:2,935,381...2,982,506
Ensembl chr Y:2,935,281...2,982,506

G

zinc finger matrin-type 4

increases expression

Amphotericin B analog results in increased expression of ZMAT4 mRNA

NCBI chr 8:40,530,590...40,897,826
Ensembl chr 8:40,530,590...40,897,833

G

zinc finger protein 155

decreases expression

Amphotericin B analog results in decreased expression of ZNF155 mRNA

NCBI chr19:43,984,188...43,998,326
Ensembl chr19:43,967,862...43,998,326

G

zinc finger protein 224

decreases expression

Amphotericin B analog results in decreased expression of ZNF224 mRNA

NCBI chr19:44,094,361...44,109,826
Ensembl chr19:44,094,361...44,109,886

G

zinc finger protein 236

increases expression

Amphotericin B analog results in increased expression of ZNF236 mRNA

NCBI chr18:76,822,557...76,972,901
Ensembl chr18:76,822,557...76,972,901

G

zinc finger protein 343

increases expression

Amphotericin B analog results in increased expression of ZNF343 mRNA; Amphotericin B results in increased expression of ZNF343 mRNA

NCBI chr20:2,481,817...2,524,999
Ensembl chr20:2,481,817...2,524,702

G

zinc finger protein 652

decreases expression

Amphotericin B results in decreased expression of ZNF652 mRNA

NCBI chr17:49,288,117...49,362,473
Ensembl chr17:49,289,206...49,362,473

G

zinc finger protein 671

decreases expression

Amphotericin B results in decreased expression of ZNF671 mRNA

NCBI chr19:57,719,751...57,727,624
Ensembl chr19:57,719,751...57,727,624

amphotericin B methyl ester

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

hepatitis A virus cellular receptor 1

increases expression

methylamphotericin B results in increased expression of HAVCR1 mRNA

NCBI chr 5:157,029,413...157,069,407
Ensembl chr 5:157,026,742...157,069,396

G

lipocalin 2

increases expression

methylamphotericin B results in increased expression of LCN2 mRNA

NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453

G

secreted phosphoprotein 1

increases expression

methylamphotericin B results in increased expression of SPP1 mRNA

NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532

G

TIMP metallopeptidase inhibitor 1

increases expression

methylamphotericin B results in increased expression of TIMP1 mRNA

NCBI chr X:47,582,436...47,586,789
Ensembl chr X:47,582,408...47,586,789

natamycin

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

clusterin

increases expression

Natamycin results in increased expression of CLU mRNA

NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700

G

ceruloplasmin

increases expression

Natamycin results in increased expression of CP mRNA

NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829

G

fibrinogen alpha chain

increases expression

Natamycin results in increased expression of FGA mRNA

NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742

G

fibrinogen gamma chain

increases expression

Natamycin results in increased expression of FGG mRNA

NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967

G

hepatitis A virus cellular receptor 1

increases expression

Natamycin results in increased expression of HAVCR1 mRNA

NCBI chr 5:157,029,413...157,069,407
Ensembl chr 5:157,026,742...157,069,396

G

keratin 19

increases expression

Natamycin results in increased expression of KRT19 mRNA

NCBI chr17:41,523,617...41,528,308
Ensembl chr17:41,523,617...41,528,308

G

lipocalin 2

increases expression

Natamycin results in increased expression of LCN2 mRNA

NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453

G

secreted phosphoprotein 1

increases expression

Natamycin results in increased expression of SPP1 mRNA

NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532

G

TIMP metallopeptidase inhibitor 1

increases expression

Natamycin results in increased expression of TIMP1 mRNA

NCBI chr X:47,582,436...47,586,789
Ensembl chr X:47,582,408...47,586,789

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	26041
role	25957
biological role	25936
antimicrobial agent	21902
polyene antibiotic	394
(3Z)-ravenic acid	0
EI-1511-3	0
TMC-1A	0
TMC-1B	0
TMC-1C	0
TMC-1D	0
amphotericin B +	390
bacillaene	0
candicidin D +	0
mediomycin A	0
mediomycin B	0
natamycin	9
nystanin	0
sceliphrolactam	0
Path 2
Term	Annotations
CHEBI ontology	26041
subatomic particle	26016
composite particle	26016
hadron	26016
baryon	26016
nucleon	26016
atomic nucleus	26016
atom	26016
main group element atom	25841
p-block element atom	25841
p-block molecular entity	25836
chalcogen molecular entity	24924
oxygen molecular entity	24814
hydroxides	24056
organic hydroxy compound	22071
polyene antibiotic	394
(3Z)-ravenic acid	0
EI-1511-3	0
TMC-1A	0
TMC-1B	0
TMC-1C	0
TMC-1D	0
amphotericin B +	390
bacillaene	0
candicidin D +	0
mediomycin A	0
mediomycin B	0
natamycin	9
nystanin	0
sceliphrolactam	0

paths to the root