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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:piperidinemonocarboxylic acid
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Accession:CHEBI:26148 term browser browse the term
Definition:Any member of the class of piperidines in which one of the carbons of the piperidine ring is substituted by a carboxy group.
Synonyms:related_synonym: piperidinemonocarboxylic acids
 alt_id: CHEBI:26150


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pipecolic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pipox pipecolic acid and sarcosine oxidase multiple interactions
increases oxidation
ISO PIPOX protein results in increased oxidation of and results in increased degradation of pipecolic acid
PIPOX protein results in increased oxidation of pipecolic acid
CTD PMID:10642506, PMID:10772957 NCBI chr10:64,951,986...64,964,865
Ensembl chr10:64,952,119...64,964,862
JBrowse link
tiagabine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase decreases activity EXP tiagabine results in decreased activity of AADAT protein CTD PMID:16765940 NCBI chr16:32,832,001...32,868,680
Ensembl chr16:32,832,061...32,868,702
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases expression
EXP Amino Acids, Peptides, and Proteins inhibits the reaction [tiagabine results in increased expression of ABCB1 protein] CTD PMID:18473823 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression EXP tiagabine results in increased expression of ABCC1 protein CTD PMID:18473823 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP tiagabine results in increased expression of ABCC2 protein CTD PMID:18473823 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO tiagabine results in decreased activity of CYP19A1 protein CTD PMID:17959350 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Kyat1 kynurenine aminotransferase 1 decreases activity EXP tiagabine results in decreased activity of KYAT1 protein CTD PMID:16765940 NCBI chr 3:8,752,289...8,785,617
Ensembl chr 3:8,752,625...8,766,433
JBrowse link
G Slc6a1 solute carrier family 6 member 1 decreases activity ISO tiagabine results in decreased activity of SLC6A1 protein CTD PMID:15788781 NCBI chr 4:146,258,842...146,292,176
Ensembl chr 4:146,276,862...146,292,213
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      chemical role 19248
        donor 18377
          Bronsted acid 18240
            oxoacid 18192
              carbon oxoacid 18071
                carboxylic acid 18060
                  monocarboxylic acid 17406
                    piperidinemonocarboxylic acid 8
                      (2R,4R)-4-methylpiperidine-2-carboxylic acid 0
                      (2S)-1-acetylpiperidine-2-carboxylic acid 0
                      1-[3-(4-carboxypiperidin-1-yl)-3-deoxy-beta-D-arabinofuranosyl]pyrimidine-2,4(1H,3H)-dione 0
                      1-piperideine-2-carboxylic acid 0
                      4-aminopiperidine-1-carboxylic acid 0
                      5-hydroxypipecolic acid + 0
                      N-[2-(4-aminophenyl)ethyl]-4-phenylisonipecotic acid + 0
                      N-hydroxypipecolic acid + 0
                      TOAC 0
                      argatroban 0
                      difenoxin + 0
                      nipecotic acid + 7
                      pipecolic acid + 1
                      piperidine-4-carboxylic acid 0
                      tiagabine 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18493
                              organic divalent group 18486
                                organodiyl group 18486
                                  carbonyl group 18389
                                    carbonyl compound 18389
                                      carboxylic acid 18060
                                        monocarboxylic acid 17406
                                          piperidinemonocarboxylic acid 8
                                            (2R,4R)-4-methylpiperidine-2-carboxylic acid 0
                                            (2S)-1-acetylpiperidine-2-carboxylic acid 0
                                            1-[3-(4-carboxypiperidin-1-yl)-3-deoxy-beta-D-arabinofuranosyl]pyrimidine-2,4(1H,3H)-dione 0
                                            1-piperideine-2-carboxylic acid 0
                                            4-aminopiperidine-1-carboxylic acid 0
                                            5-hydroxypipecolic acid + 0
                                            N-[2-(4-aminophenyl)ethyl]-4-phenylisonipecotic acid + 0
                                            N-hydroxypipecolic acid + 0
                                            TOAC 0
                                            argatroban 0
                                            difenoxin + 0
                                            nipecotic acid + 7
                                            pipecolic acid + 1
                                            piperidine-4-carboxylic acid 0
                                            tiagabine 7
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