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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:pheromone
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Accession:CHEBI:26013 term browser browse the term
Definition:A semiochemical used in olfactory communication between organisms of the same species eliciting a change in sexual or social behaviour.
Synonyms:related_synonym: ectohormone;   feromone;   pheromones
 xref: PMID:23988175;   Wikipedia:Pheromone

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5alpha-androst-16-en-3alpha-ol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 multiple interactions EXP [1,4-bis(2-(3,5-dichloropyridyloxy))benzene inhibits the reaction [androst-16-en-3-ol results in decreased activity of NR1I3 protein]] which results in increased expression of CYP2B6 mRNA; [Endosulfan inhibits the reaction [androst-16-en-3-ol results in decreased activity of NR1I3 protein]] which results in increased expression of CYP2B6 mRNA CTD PMID:20361990 NCBI chr 7:25,897,658...25,926,624
Ensembl chr 7:25,897,620...25,926,624 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 decreases activity
multiple interactions		 EXP androst-16-en-3-ol results in decreased activity of NR1I3 protein
1,4-bis(2-(3,5-dichloropyridyloxy))benzene inhibits the reaction [androst-16-en-3-ol results in decreased activity of NR1I3 protein]; [1,4-bis(2-(3,5-dichloropyridyloxy))benzene inhibits the reaction [androst-16-en-3-ol results in decreased activity of NR1I3 protein]] which results in increased expression of CYP2B6 mRNA; [Endosulfan inhibits the reaction [androst-16-en-3-ol results in decreased activity of NR1I3 protein]] which results in increased expression of CYP2B6 mRNA		 CTD PMID:20361990 NCBI chr 1:171,213,934...171,218,845
Ensembl chr 1:171,213,970...171,220,701 		JBrowse link
actinidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ocln occludin increases cleavage ISO actinidine results in increased cleavage of OCLN protein CTD PMID:25042511 NCBI chr13:100,496,504...100,552,718
Ensembl chr13:100,496,507...100,552,718 		JBrowse link
dodecan-1-ol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf3 activating transcription factor 3 increases expression ISO Dodecanol analog results in increased expression of ATF3 mRNA CTD PMID:27965148 NCBI chr 1:191,170,296...191,183,333
Ensembl chr 1:191,170,296...191,218,039 		JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 increases expression ISO Dodecanol analog results in increased expression of CXCL8 mRNA CTD PMID:27965148 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067 		JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO Dodecanol analog results in increased expression of DNAJB4 mRNA CTD PMID:27965148 NCBI chr 3:152,181,580...152,210,432
Ensembl chr 3:152,178,511...152,210,302 		JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit increases expression ISO Dodecanol analog results in increased expression of GCLM mRNA CTD PMID:27965148 NCBI chr 3:122,245,487...122,267,215
Ensembl chr 3:122,245,557...122,270,732 		JBrowse link
geranic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tyr tyrosinase decreases expression EXP decaprenoic acid results in decreased expression of TYR protein CTD PMID:23286867 NCBI chr 7:87,424,771...87,493,512
Ensembl chr 7:87,424,771...87,493,512 		JBrowse link
heptan-2-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gna15 guanine nucleotide binding protein, alpha 15 multiple interactions
increases response to substance		 ISO [GNA15 protein results in increased susceptibility to 2-heptanone] which results in decreased activity of OLFR154 protein CTD PMID:15598656 NCBI chr10:81,502,313...81,524,447
Ensembl chr10:81,502,306...81,524,225 		JBrowse link
G Gnal guanine nucleotide binding protein, alpha stimulating, olfactory type increases response to substance
multiple interactions		 ISO GNAL protein results in increased susceptibility to 2-heptanone
[GNAL protein results in increased susceptibility to 2-heptanone] which results in increased activity of OLFR154 protein		 CTD PMID:15598656 NCBI chr18:67,088,298...67,226,792
Ensembl chr18:67,088,216...67,226,792 		JBrowse link
G Gstp1 glutathione S-transferase, pi 1 decreases activity ISO 2-heptanone results in decreased activity of GSTP1 protein CTD PMID:18409811 NCBI chr19:4,035,411...4,037,912
Ensembl chr19:4,035,407...4,037,985 		JBrowse link
G Olfr1002 olfactory receptor 1002 multiple interactions ISO [GNA15 protein results in increased susceptibility to 2-heptanone] which results in decreased activity of OLFR154 protein; [GNAL protein results in increased susceptibility to 2-heptanone] which results in increased activity of OLFR154 protein CTD PMID:15598656 NCBI chr 2:85,647,363...85,648,319
Ensembl chr 2:85,646,057...85,650,704 		JBrowse link
G Olfr154 olfactory receptor 154 increases activity EXP 2-heptanone results in increased activity of OLFR154 protein CTD PMID:15598656 NCBI chr 2:85,663,377...85,664,455
Ensembl chr 2:85,663,377...85,664,455 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21569
    role 21548
      biological role 21546
        molecular messenger 18818
          semiochemical 13
            pheromone 13
              (E)-non-2-en-1-ol + 0
              (R)-3-[(R)-3-hydroxybutanoyloxy]butanoic acid 0
              (R)-3-hydroxybutyric acid + 0
              (Z)-hexadec-11-enal 0
              (Z)-non-6-en-1-ol 0
              1-heptadecene 0
              2-isobutylthiazole 0
              2-methoxy-4-vinylphenol 0
              2-nonanol + 0
              3-hydroxy-3-methylbut-1-ene 0
              5alpha-androst-16-en-3-one 0
              5alpha-androst-16-en-3alpha-ol 2
              actinidine 1
              alarm pheromone + 0
              ascr#1 + 0
              ascr#2 + 0
              ascr#3 + 0
              ascr#4 0
              ascr#5 0
              ascr#7 + 0
              ascr#8 0
              bombykol 0
              cis-cis-nepetalactol 0
              cis-isogeraniol 0
              cis-trans-nepetalactone 0
              civetone 0
              coniferol + 0
              dodecan-1-ol + 4
              felinine 0
              geranic acid 1
              henicosane + 0
              heptan-2-one 5
              lavandulol + 0
              palmityl acetate 0
              pentan-3-ol 0
              peptide pheromone + 0
              phenylacetonitrile + 0
              sulcatol 0
              trisporic acid 0
paths to the root