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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:pheromone
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Accession:CHEBI:26013 term browser browse the term
Definition:A semiochemical used in olfactory communication between organisms of the same species eliciting a change in sexual or social behaviour.
Synonyms:related_synonym: ectohormone;   feromone;   pheromones
 xref: PMID:23988175;   Wikipedia:Pheromone

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5alpha-androst-16-en-3alpha-ol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 multiple interactions ISO [1,4-bis(2-(3,5-dichloropyridyloxy))benzene inhibits the reaction [androst-16-en-3-ol results in decreased activity of NR1I3 protein]] which results in increased expression of CYP2B6 mRNA; [Endosulfan inhibits the reaction [androst-16-en-3-ol results in decreased activity of NR1I3 protein]] which results in increased expression of CYP2B6 mRNA CTD PMID:20361990 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398 		JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 decreases activity
multiple interactions		 ISO androst-16-en-3-ol results in decreased activity of NR1I3 protein
1,4-bis(2-(3,5-dichloropyridyloxy))benzene inhibits the reaction [androst-16-en-3-ol results in decreased activity of NR1I3 protein]; [1,4-bis(2-(3,5-dichloropyridyloxy))benzene inhibits the reaction [androst-16-en-3-ol results in decreased activity of NR1I3 protein]] which results in increased expression of CYP2B6 mRNA; [Endosulfan inhibits the reaction [androst-16-en-3-ol results in decreased activity of NR1I3 protein]] which results in increased expression of CYP2B6 mRNA		 CTD PMID:20361990 NCBI chr 1:161,229,666...161,238,623
Ensembl chr 1:161,229,666...161,238,302
Ensembl chr 1:161,229,666...161,238,302 		JBrowse link
actinidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OCLN occludin increases cleavage EXP actinidine results in increased cleavage of OCLN protein CTD PMID:25042511 NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104 		JBrowse link
dodecan-1-ol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF3 activating transcription factor 3 increases expression EXP Dodecanol analog results in increased expression of ATF3 mRNA CTD PMID:27965148 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression EXP Dodecanol analog results in increased expression of CXCL8 mRNA CTD PMID:27965148 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,541...73,743,716 		JBrowse link
G DNAJB4 DnaJ heat shock protein family (Hsp40) member B4 increases expression EXP Dodecanol analog results in increased expression of DNAJB4 mRNA CTD PMID:27965148 NCBI chr 1:77,979,175...78,017,964
Ensembl chr 1:77,979,175...78,017,964 		JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit increases expression EXP Dodecanol analog results in increased expression of GCLM mRNA CTD PMID:27965148 NCBI chr 1:93,885,199...93,910,370
Ensembl chr 1:93,885,199...93,909,456 		JBrowse link
geranic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TYR tyrosinase decreases expression ISO decaprenoic acid results in decreased expression of TYR protein CTD PMID:23286867 NCBI chr11:89,177,565...89,295,759
Ensembl chr11:89,177,875...89,295,759 		JBrowse link
heptan-2-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GNA15 G protein subunit alpha 15 increases response to substance
multiple interactions		 EXP GNA15 protein results in increased susceptibility to 2-heptanone
[GNA15 protein results in increased susceptibility to 2-heptanone] which results in decreased activity of OLFR154 protein		 CTD PMID:15598656 NCBI chr19:3,136,033...3,163,749
Ensembl chr19:3,136,033...3,163,749 		JBrowse link
G GNAL G protein subunit alpha L multiple interactions
increases response to substance		 EXP [GNAL protein results in increased susceptibility to 2-heptanone] which results in increased activity of OLFR154 protein CTD PMID:15598656 NCBI chr18:11,689,015...11,885,685
Ensembl chr18:11,689,264...11,885,685 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 decreases activity EXP 2-heptanone results in decreased activity of GSTP1 protein CTD PMID:18409811 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G OR5G5P olfactory receptor family 5 subfamily G member 5 pseudogene multiple interactions EXP [GNA15 protein results in increased susceptibility to 2-heptanone] which results in decreased activity of OLFR154 protein; [GNAL protein results in increased susceptibility to 2-heptanone] which results in increased activity of OLFR154 protein CTD PMID:15598656 NCBI chr11:56,801,859...56,802,794
Ensembl chr11:56,801,856...56,820,422 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 24387
    role 24297
      biological role 24264
        molecular messenger 19166
          semiochemical 12
            pheromone 12
              (E)-non-2-en-1-ol + 0
              (R)-3-[(R)-3-hydroxybutanoyloxy]butanoic acid 0
              (R)-3-hydroxybutyric acid + 0
              (Z)-hexadec-11-enal 0
              (Z)-non-6-en-1-ol 0
              1-heptadecene 0
              2-isobutylthiazole 0
              2-methoxy-4-vinylphenol 0
              2-nonanol + 0
              3-hydroxy-3-methylbut-1-ene 0
              5alpha-androst-16-en-3-one 0
              5alpha-androst-16-en-3alpha-ol 2
              actinidine 1
              alarm pheromone + 0
              ascr#1 + 0
              ascr#2 + 0
              ascr#3 + 0
              ascr#4 0
              ascr#5 0
              ascr#7 + 0
              ascr#8 0
              bombykol 0
              cis-cis-nepetalactol 0
              cis-isogeraniol 0
              cis-trans-nepetalactone 0
              civetone 0
              coniferol + 0
              dodecan-1-ol + 4
              felinine 0
              geranic acid 1
              henicosane + 0
              heptan-2-one 4
              lavandulol + 0
              palmityl acetate 0
              pentan-3-ol 0
              peptide pheromone + 0
              phenylacetonitrile + 0
              sulcatol 0
              trisporic acid 0
paths to the root