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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:pheromone
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Accession:CHEBI:26013 term browser browse the term
Definition:A semiochemical used in olfactory communication between organisms of the same species eliciting a change in sexual or social behaviour.
Synonyms:related_synonym: ectohormone;   feromone;   pheromones
 xref: PMID:23988175;   Wikipedia:Pheromone


show annotations for term's descendants           Sort by:
(+)-pinoresinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions
decreases expression 		ISO [loliolide co-treated with pinoresinol] results in decreased expression of ACACA protein
pinoresinol results in decreased expression of ACACA protein 		CTD PMID:31610126 NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888 		JBrowse link
G Fasn fatty acid synthase multiple interactions
decreases expression 		ISO [loliolide co-treated with pinoresinol] results in decreased expression of FASN protein
pinoresinol results in decreased expression of FASN protein 		CTD PMID:31610126 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583 		JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 multiple interactions ISO pinoresinol results in increased ubiquitination of and results in increased degradation of and results in decreased expression of NR1H2 protein CTD PMID:31610126 NCBI chr 1:104,178,483...104,183,863
Ensembl chr 1:104,178,234...104,183,863 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions ISO pinoresinol results in increased ubiquitination of and results in increased degradation of and results in decreased expression of NR1H3 protein CTD PMID:31610126 NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:97,614,616...97,624,532 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO pinoresinol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:21191767 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression
multiple interactions 		ISO pinoresinol results in decreased expression of SREBF1 protein
[loliolide co-treated with pinoresinol] results in decreased expression of SREBF1 protein 		CTD PMID:31610126 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164 		JBrowse link
G Tnf tumor necrosis factor decreases secretion ISO pinoresinol results in decreased secretion of TNF protein CTD PMID:29740324 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP fluorotelomer alcohols results in increased expression of ABCC3 mRNA CTD PMID:38903859 NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494 		JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 decreases expression EXP fluorotelomer alcohols results in decreased expression of ABCG5 mRNA CTD PMID:38903859 NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:15,717,936...15,743,376 		JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 increases expression EXP fluorotelomer alcohols results in increased expression of ACAT1 mRNA CTD PMID:38903859 NCBI chr 8:62,876,003...62,905,080
Ensembl chr 8:62,876,003...62,905,042 		JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression EXP fluorotelomer alcohols results in increased expression of ACOX1 mRNA CTD PMID:38903859 NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,905,083...101,930,136 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 increases expression EXP fluorotelomer alcohols results in increased expression of ACSL1 mRNA CTD PMID:38903859 NCBI chr16:52,487,870...52,554,110
Ensembl chr16:52,487,870...52,554,023 		JBrowse link
G Angptl4 angiopoietin-like 4 increases expression EXP fluorotelomer alcohols results in increased expression of ANGPTL4 mRNA CTD PMID:38903859 NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:15,252,473...15,258,681 		JBrowse link
G Ccna1 cyclin A1 decreases expression ISO fluorotelomer alcohols results in decreased expression of CCNA1 mRNA CTD PMID:30794351 NCBI chr 2:141,383,352...141,428,205
Ensembl chr 2:141,382,468...141,393,300 		JBrowse link
G Ccna2 cyclin A2 decreases expression ISO fluorotelomer alcohols results in decreased expression of CCNA2 mRNA CTD PMID:30794351 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO fluorotelomer alcohols results in decreased expression of CCND1 mRNA CTD PMID:30794351 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G Ccne2 cyclin E2 decreases expression ISO fluorotelomer alcohols results in decreased expression of CCNE2 mRNA CTD PMID:30794351 NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:29,082,703...29,094,882 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression EXP fluorotelomer alcohols results in decreased expression of CDKN1A mRNA CTD PMID:38903859 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Cebpe CCAAT/enhancer binding protein epsilon decreases expression ISO fluorotelomer alcohols results in decreased expression of CEBPE mRNA CTD PMID:30794351 NCBI chr15:32,139,716...32,141,476
Ensembl chr15:32,139,716...32,141,476 		JBrowse link
G Csf3r colony stimulating factor 3 receptor decreases expression ISO fluorotelomer alcohols results in decreased expression of CSF3R mRNA CTD PMID:30794351 NCBI chr 5:143,583,126...143,604,382
Ensembl chr 5:143,583,213...143,602,411 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression ISO fluorotelomer alcohols results in decreased expression of CXCL1 mRNA CTD PMID:30536526 NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression ISO fluorotelomer alcohols results in decreased expression of CYP11A1 mRNA; fluorotelomer alcohols results in decreased expression of CYP11A1 protein CTD PMID:20615422 NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 decreases expression ISO fluorotelomer alcohols results in decreased expression of CYP11B1 mRNA; fluorotelomer alcohols results in decreased expression of CYP11B1 protein CTD PMID:20615422 NCBI chr 7:108,719,349...108,726,024
Ensembl chr 7:108,719,349...108,725,763 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 decreases expression ISO fluorotelomer alcohols results in decreased expression of CYP11B2 mRNA; fluorotelomer alcohols results in decreased expression of CYP11B2 protein CTD PMID:20615422 NCBI chr 7:108,689,319...108,694,808
Ensembl chr 7:108,689,165...108,694,921 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression ISO fluorotelomer alcohols results in decreased expression of CYP17A1 mRNA; fluorotelomer alcohols results in decreased expression of CYP17A1 protein CTD PMID:20615422 NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression ISO fluorotelomer alcohols results in increased expression of CYP19A1 mRNA CTD PMID:23142464 NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases expression EXP fluorotelomer alcohols results in decreased expression of CYP1A2 mRNA CTD PMID:38903859 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO fluorotelomer alcohols results in decreased activity of CYP2E1 protein CTD PMID:35121066 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 affects expression EXP fluorotelomer alcohols affects the expression of CYP7A1 mRNA CTD PMID:38903859 NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases expression ISO fluorotelomer alcohols results in decreased expression of ERBB2 mRNA CTD PMID:16393665 NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,907,460...83,931,481 		JBrowse link
G Esr1 estrogen receptor 1 increases activity
multiple interactions
increases expression 		ISO fluorotelomer alcohols results in increased activity of ESR1 protein
fluorotelomer alcohols promotes the reaction [ESR1 protein binds to NCOA2 protein]
fluorotelomer alcohols results in increased expression of ESR1 mRNA 		CTD PMID:16393665 PMID:17603182 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
increases activity 		ISO fluorotelomer alcohols promotes the reaction [ESR2 protein binds to NCOA2 protein]
fluorotelomer alcohols results in increased activity of ESR2 protein 		CTD PMID:17603182 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709 		JBrowse link
G G0s2 G0/G1switch 2 affects expression EXP fluorotelomer alcohols affects the expression of G0S2 mRNA CTD PMID:38903859 NCBI chr13:107,335,036...107,335,948
Ensembl chr13:107,335,036...107,336,293 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha decreases expression ISO fluorotelomer alcohols results in decreased expression of HNF4A mRNA CTD PMID:38953992 NCBI chr 3:172,606,220...172,667,758
Ensembl chr 3:172,606,220...172,667,758 		JBrowse link
G Ifng interferon gamma multiple interactions ISO fluorotelomer alcohols inhibits the reaction [Mitogens results in increased secretion of IFNG protein] CTD PMID:30536526 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 affects expression EXP fluorotelomer alcohols affects the expression of IGFBP1 mRNA CTD PMID:38903859 NCBI chr14:86,261,277...86,266,344
Ensembl chr14:86,261,277...86,266,344 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression EXP fluorotelomer alcohols results in decreased expression of IGFBP3 mRNA CTD PMID:38903859 NCBI chr14:86,270,208...86,277,944
Ensembl chr14:86,270,208...86,277,944 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
affects expression 		ISO fluorotelomer alcohols results in decreased expression of and results in decreased secretion of IL1B protein
fluorotelomer alcohols affects the expression of IL1B mRNA 		CTD PMID:30536526 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il6 interleukin 6 decreases expression ISO fluorotelomer alcohols results in decreased expression of IL6 mRNA CTD PMID:30536526 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Insig1 insulin induced gene 1 decreases expression ISO fluorotelomer alcohols results in decreased expression of INSIG1 mRNA CTD PMID:38953992 NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:8,049,556...8,057,778 		JBrowse link
G Itgam integrin subunit alpha M decreases expression ISO fluorotelomer alcohols results in decreased expression of ITGAM mRNA CTD PMID:30794351 NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943 		JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid decreases expression EXP fluorotelomer alcohols results in decreased expression of MFSD2A mRNA CTD PMID:38903859 NCBI chr 5:140,510,933...140,525,828
Ensembl chr 5:140,510,953...140,525,916 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor affects expression EXP fluorotelomer alcohols affects the expression of MYC mRNA CTD PMID:38903859 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO fluorotelomer alcohols promotes the reaction [ESR1 protein binds to NCOA2 protein]; fluorotelomer alcohols promotes the reaction [ESR2 protein binds to NCOA2 protein] CTD PMID:17603182 NCBI chr 5:10,618,712...10,852,776
Ensembl chr 5:10,618,722...10,852,776 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP fluorotelomer alcohols results in increased expression of NQO1 mRNA CTD PMID:38903859 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 affects expression EXP fluorotelomer alcohols affects the expression of PCK1 mRNA CTD PMID:38903859 NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561 		JBrowse link
G Pdzk1 PDZ domain containing 1 increases expression ISO fluorotelomer alcohols results in increased expression of PDZK1 mRNA CTD PMID:16393665 NCBI chr 2:187,064,995...187,096,348
Ensembl chr 2:187,065,013...187,096,806 		JBrowse link
G Pgr progesterone receptor increases expression ISO fluorotelomer alcohols results in increased expression of PGR mRNA CTD PMID:16393665 NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta decreases expression ISO fluorotelomer alcohols results in decreased expression of PPARD mRNA CTD PMID:38953992 NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,352,183...6,365,707 		JBrowse link
G Scd stearoyl-CoA desaturase increases expression EXP fluorotelomer alcohols results in increased expression of SCD mRNA CTD PMID:38903859 NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785 		JBrowse link
G Slc22a7 solute carrier family 22 member 7 increases expression EXP fluorotelomer alcohols results in increased expression of SLC22A7 mRNA CTD PMID:21530637 NCBI chr 9:22,044,672...22,052,051
Ensembl chr 9:22,045,435...22,051,681 		JBrowse link
G Spi1 Spi-1 proto-oncogene decreases expression ISO fluorotelomer alcohols results in decreased expression of SPI1 mRNA CTD PMID:30794351 NCBI chr 3:97,529,509...97,548,204
Ensembl chr 3:97,527,572...97,549,540 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression ISO fluorotelomer alcohols results in decreased expression of STAR mRNA; fluorotelomer alcohols results in decreased expression of STAR protein CTD PMID:20615422 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447 		JBrowse link
G Tat tyrosine aminotransferase affects expression EXP fluorotelomer alcohols affects the expression of TAT mRNA CTD PMID:38903859 NCBI chr19:54,856,604...54,867,168
Ensembl chr19:54,856,563...54,867,482 		JBrowse link
G Tff1 trefoil factor 1 increases expression ISO fluorotelomer alcohols results in increased expression of TFF1 mRNA CTD PMID:16393665 NCBI chr20:9,237,095...9,240,956
Ensembl chr20:9,237,095...9,240,956 		JBrowse link
G Tnf tumor necrosis factor decreases expression ISO fluorotelomer alcohols results in decreased expression of TNF mRNA CTD PMID:30536526 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tspo translocator protein decreases expression ISO fluorotelomer alcohols results in decreased expression of TSPO mRNA CTD PMID:23142464 NCBI chr 7:116,600,214...116,610,461
Ensembl chr 7:116,600,210...116,610,460 		JBrowse link
5alpha-androst-16-en-3alpha-ol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO [1,4-bis(2-(3,5-dichloropyridyloxy))benzene inhibits the reaction [androst-16-en-3-ol results in decreased activity of NR1I3 protein]] which results in increased expression of CYP2B6 mRNA; [Endosulfan inhibits the reaction [androst-16-en-3-ol results in decreased activity of NR1I3 protein]] which results in increased expression of CYP2B6 mRNA CTD PMID:20361990 NCBI chr 1:90,780,468...90,859,852 JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 decreases activity
multiple interactions 		ISO androst-16-en-3-ol results in decreased activity of NR1I3 protein
1,4-bis(2-(3,5-dichloropyridyloxy))benzene inhibits the reaction [androst-16-en-3-ol results in decreased activity of NR1I3 protein]; [1,4-bis(2-(3,5-dichloropyridyloxy))benzene inhibits the reaction [androst-16-en-3-ol results in decreased activity of NR1I3 protein]] which results in increased expression of CYP2B6 mRNA; [Endosulfan inhibits the reaction [androst-16-en-3-ol results in decreased activity of NR1I3 protein]] which results in increased expression of CYP2B6 mRNA 		CTD PMID:20361990 NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370 		JBrowse link
actinidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ocln occludin increases cleavage ISO actinidine results in increased cleavage of OCLN protein CTD PMID:25042511 NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411 		JBrowse link
androsterone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c14 aldo-keto reductase family 1, member C14 increases reduction EXP AKR1C14 protein results in increased reduction of Androsterone CTD PMID:1922097 NCBI chr17:71,066,197...71,083,184
Ensembl chr17:71,066,200...71,083,157 		JBrowse link
G Ar androgen receptor affects binding EXP Androsterone binds to AR protein CTD PMID:14565775 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 affects chemical synthesis ISO CYP17A1 protein affects the chemical synthesis of Androsterone CTD PMID:14522586 NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974 		JBrowse link
G Dhrs11 dehydrogenase/reductase 11 increases reduction ISO DHRS11 protein results in increased reduction of Androsterone CTD PMID:30926317 NCBI chr10:70,195,637...70,205,735
Ensembl chr10:70,195,637...70,205,893 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity EXP Androsterone results in decreased activity of G6PD protein CTD PMID:7752092 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144 		JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 increases metabolic processing ISO HSD17B12 protein results in increased metabolism of Androsterone CTD PMID:17641292 NCBI chr 3:100,445,393...100,568,898
Ensembl chr 3:100,445,400...100,568,938 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Androsterone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions ISO Androsterone inhibits the reaction [UGT1A1 protein results in increased glucuronidation of Diethylstilbestrol] CTD PMID:23126256 NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 multiple interactions ISO Androsterone inhibits the reaction [[UGT1A3 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]; Androsterone inhibits the reaction [UGT1A3 protein results in increased glucuronidation of Hymecromone] CTD PMID:33290829 NCBI chr 9:96,239,019...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 increases glucuronidation ISO UGT1A4 protein SNP results in increased glucuronidation of Androsterone analog CTD PMID:15708967 NCBI chr 9:96,210,053...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Ugt2b UDP glycosyltransferase 2 family, polypeptide B increases glucuronidation EXP UGT2B protein results in increased glucuronidation of Androsterone CTD PMID:2429951 NCBI chr14:20,985,449...21,006,267
Ensembl chr14:20,985,108...21,020,850 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 increases metabolic processing ISO UGT2B17 protein results in increased metabolism of Androsterone CTD PMID:8798464 NCBI chr14:21,378,882...21,390,631
Ensembl chr14:21,378,853...21,392,331 		JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 increases glucuronidation
decreases activity
multiple interactions 		ISO UGT2B7 protein results in increased glucuronidation of Androsterone
Androsterone results in decreased activity of UGT2B7 protein
Androsterone inhibits the reaction [[UGT2B7 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]; Androsterone inhibits the reaction [UGT2B7 protein results in increased glucuronidation of Diethylstilbestrol]; Androsterone inhibits the reaction [UGT2B7 protein results in increased glucuronidation of Hymecromone] 		CTD PMID:11186130 PMID:23126256 PMID:26875642 PMID:33290829 NCBI chr14:21,251,535...21,274,451
Ensembl chr14:21,251,535...21,274,451 		JBrowse link
androsterone 3-glucosiduronic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kl Klotho multiple interactions ISO androsterone glucuronide inhibits the reaction [KL protein results in increased hydrolysis of Glucuronides] CTD PMID:14701853 NCBI chr12:5,326,003...5,367,016
Ensembl chr12:5,325,959...5,367,015 		JBrowse link
decan-1-ol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b15 aldo-keto reductase family 1 member B15 multiple interactions EXP [AKR1B8 protein co-treated with NADP] affects the oxidation of n-decyl alcohol CTD PMID:18845131 NCBI chr 4:63,964,421...63,976,995
Ensembl chr 4:63,960,880...63,978,349 		JBrowse link
G Cftr CF transmembrane conductance regulator increases activity ISO n-decyl alcohol results in increased activity of CFTR protein CTD PMID:14967738 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643 		JBrowse link
dodecan-1-ol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf3 activating transcription factor 3 increases expression ISO Dodecanol analog results in increased expression of ATF3 mRNA CTD PMID:27965148 NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750 		JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO Dodecanol analog results in increased expression of DNAJB4 mRNA CTD PMID:27965148 NCBI chr 2:243,790,296...243,819,042
Ensembl chr 2:243,790,297...243,819,042 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Dodecanol analog results in increased expression of GCLM mRNA CTD PMID:27965148 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003 		JBrowse link
geranic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tyr tyrosinase decreases expression ISO decaprenoic acid results in decreased expression of TYR protein CTD PMID:23286867 NCBI chr 1:150,527,687...150,622,857
Ensembl chr 1:150,527,687...150,622,857 		JBrowse link
heptan-2-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gna15 G protein subunit alpha 15 increases response to substance
multiple interactions 		ISO GNA15 protein results in increased susceptibility to 2-heptanone
[GNA15 protein results in increased susceptibility to 2-heptanone] which results in decreased activity of OR5G26 protein 		CTD PMID:15598656 NCBI chr 7:8,835,396...8,856,269
Ensembl chr 7:8,835,357...8,856,268 		JBrowse link
G Gnal G protein subunit alpha L multiple interactions
increases response to substance 		ISO [GNAL protein results in increased susceptibility to 2-heptanone] which results in increased activity of OR5G26 protein CTD PMID:15598656 NCBI chr18:62,892,257...63,032,510
Ensembl chr18:62,892,226...63,043,129 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases activity ISO 2-heptanone results in decreased activity of GSTP1 protein CTD PMID:18409811 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705 		JBrowse link
G Or5g29 olfactory receptor family 5 subfamily G member 29 multiple interactions ISO [GNA15 protein results in increased susceptibility to 2-heptanone] which results in decreased activity of OR5G26 protein; [GNAL protein results in increased susceptibility to 2-heptanone] which results in increased activity of OR5G26 protein CTD PMID:15598656 NCBI chr 3:91,089,444...91,090,388
Ensembl chr 3:91,089,444...91,090,388 		JBrowse link
hexan-1-ol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b15 aldo-keto reductase family 1 member B15 multiple interactions EXP [AKR1B8 protein co-treated with NADP] affects the oxidation of 1-hexanol CTD PMID:18845131 NCBI chr 4:63,964,421...63,976,995
Ensembl chr 4:63,960,880...63,978,349 		JBrowse link
monohexyl phthalate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsf1 heat shock transcription factor 1 increases activity ISO mono-n-hexyl phthalate results in increased activity of HSF1 protein CTD PMID:34170685 NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:110,076,710...110,103,665 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha affects binding ISO mono-n-hexyl phthalate binds to PPARA protein CTD PMID:23843199 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta affects binding ISO mono-n-hexyl phthalate binds to PPARB protein CTD PMID:23843199 NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,352,183...6,365,707 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding ISO mono-n-hexyl phthalate binds to PPARG protein CTD PMID:23843199 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
nerolidol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions EXP [nerolidol co-treated with AGT protein] results in increased expression of GPX4 protein; nerolidol inhibits the reaction [AGT protein results in decreased expression of CAT protein]; nerolidol inhibits the reaction [AGT protein results in decreased expression of SOD2 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of AGTR1A protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of IL6 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of MMP2 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of MMP9 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of NOS2 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of PTGS2 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of TGFB1 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of TLR4 protein]; nerolidol inhibits the reaction [AGT protein results in increased expression of TNF protein]; nerolidol inhibits the reaction [AGT protein results in increased phosphorylation of and affects the localization of RELA protein]; nerolidol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; nerolidol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein] CTD PMID:33212213 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of AGTR1A protein] CTD PMID:33212213 NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased phosphorylation of AKT1 protein] CTD PMID:36169646 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO nerolidol results in increased expression of BAX mRNA CTD PMID:35357761 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO nerolidol results in decreased expression of BCL2 mRNA CTD PMID:35357761 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Casp3 caspase 3 increases expression ISO nerolidol results in increased expression of CASP3 mRNA CTD PMID:35357761 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Cat catalase multiple interactions EXP nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; nerolidol inhibits the reaction [AGT protein results in decreased expression of CAT protein] CTD PMID:33212213 PMID:36169646 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO nerolidol results in decreased expression of CCND1 mRNA CTD PMID:35357761 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions EXP nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of G6PD protein] CTD PMID:36169646 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144 		JBrowse link
G Gck glucokinase multiple interactions EXP nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of GCK protein] CTD PMID:36169646 NCBI chr14:84,999,019...85,041,098
Ensembl chr14:84,999,020...85,040,949 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein] CTD PMID:36169646 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions EXP [nerolidol co-treated with AGT protein] results in increased expression of GPX4 protein CTD PMID:33212213 NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of IL6 protein] CTD PMID:33212213 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Ins1 insulin 1 multiple interactions EXP nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein] CTD PMID:36169646 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682 		JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions EXP nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of IRS1 protein] CTD PMID:36169646 NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein] CTD PMID:33212213 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein] CTD PMID:33212213 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO nerolidol results in increased expression of and results in increased phosphorylation of MAPK8 mRNA CTD PMID:35357761 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of MMP2 protein] CTD PMID:33212213 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of MMP9 protein] CTD PMID:33212213 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of NOS2 protein] CTD PMID:33212213 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of PTGS2 protein] CTD PMID:33212213 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased phosphorylation of and affects the localization of RELA protein] CTD PMID:33212213 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions EXP nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein] CTD PMID:36169646 NCBI chr10:55,164,721...55,170,289
Ensembl chr10:55,164,721...55,170,270 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in decreased expression of SOD2 protein] CTD PMID:33212213 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of TGFB1 protein] CTD PMID:33212213 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of TLR4 protein] CTD PMID:33212213 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP nerolidol inhibits the reaction [AGT protein results in increased expression of TNF protein] CTD PMID:33212213 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      biological role 20818
        molecular messenger 19442
          semiochemical 109
            pheromone 108
              (1S,6S,7R)-sesquipiperitol 0
              (2E,4E,6E)-nonatrienal 0
              (2E,4E,6Z)-nonatrienal 0
              (6R,7S)-himachala-9,11-diene 0
              (7Z)-tricosene 0
              (7Z,11Z)-nonacosadiene 0
              (E)-non-2-en-1-ol + 0
              (E,E)-2,4-hexadienyl acetate 0
              (R)-3-[(R)-3-hydroxybutanoyloxy]butanoic acid 0
              (R)-3-hydroxybutyric acid + 0
              (Z)-hexadec-11-enal 0
              (Z)-non-6-en-1-ol 0
              (Z)-pentacos-7-ene 0
              1-heptadecene 0
              2-butyl-3,5-dimethylpyrazine 0
              2-isobutylthiazole 0
              2-methoxy-4-vinylphenol 0
              2-methylhexacosane 0
              3-ethyl-2,7-dimethyloctane 0
              3-hydroxy-3-methylbut-1-ene 0
              5alpha-androst-16-en-3-one 0
              5alpha-androst-16-en-3alpha-ol 2
              6-oxo-nonan-1-ol 0
              7-methylmellein 0
              7-methyltricosane 0
              7-tricosene + 0
              N-acetyl-D-glucosamino-1,5-lactone + 0
              actinidine 1
              alarm pheromone + 5
              androsterone + 14
              ascr#1 + 0
              ascr#2 + 0
              ascr#3 + 0
              ascr#4 0
              ascr#5 0
              ascr#7 + 0
              ascr#8 0
              bombykol 0
              cis-cis-nepetalactol 0
              cis-isogeraniol 0
              cis-trans-nepetalactone 0
              civetone 0
              coniferol + 7
              decan-1-ol + 52
              decan-3-ol 0
              dodecan-1-ol + 3
              felinine 0
              geranic acid 1
              geranylgeranyl acetate 0
              henicosane + 0
              heptacosa-7,11-diene 0
              heptan-2-one 4
              hexan-3-ol 0
              lauryl acrylate 0
              lavandulol + 0
              linalool oxide pyranoside + 0
              nerolidol + 28
              nonan-2-ol + 0
              nonan-5-ol 0
              octan-3-ol 0
              palmityl acetate 0
              pentadecan-2-ol 0
              pentan-3-ol 0
              peptide pheromone + 0
              phenylacetonitrile + 0
              sobralene 0
              sulcatol 0
              tetradecan-1-ol + 0
              tridecan-2-ol 0
              trimethylpyrazine 0
              trisporic acid 0
              undecan-2-ol 0
paths to the root