The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Any organic aromatic compound with a structure based on a phenylpropane skeleton. The class includes naturally occurring phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules as well as their semi-synthetic and synthetic analogues. Phenylpropanoids are also precursors of lignin.
epigallocatechin gallate inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl affects the localization of and results in increased activity of AHR protein]; epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased activity of AHR protein]; epigallocatechin gallate inhibits the reaction [[alpha-naphthoflavone co-treated with 3,4,3',4'-tetrachlorobiphenyl] results in increased activity of AHR protein]; epigallocatechin gallate inhibits the reaction [alpha-naphthoflavone results in increased activity of AHR protein]
epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA]; epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 protein]; epigallocatechin gallate inhibits the reaction [titanium dioxide results in increased expression of CCL2 mRNA]; epigallocatechin gallate inhibits the reaction [TNF protein results in increased expression of CCL2 protein]; HMOX1 protein promotes the reaction [epigallocatechin gallate inhibits the reaction [TNF protein results in increased expression of CCL2 protein]] epigallocatechin gallate results in decreased expression of CCL2 mRNA
epigallocatechin gallate inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased activity of CYP1A1 protein]; epigallocatechin gallate inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 mRNA]; epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein]; epigallocatechin gallate inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; epigallocatechin gallate inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA] epigallocatechin gallate results in decreased activity of CYP1A1 protein epigallocatechin gallate results in decreased expression of CYP1A1 mRNA
[epigallocatechin gallate co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of GSTO1 mRNA; NFE2L2 protein affects the reaction [epigallocatechin gallate results in increased expression of GSTO1 mRNA]
NFE2L2 protein affects the reaction [epigallocatechin gallate results in increased expression of GSTO1 mRNA]; NFE2L2 protein affects the reaction [epigallocatechin gallate results in increased expression of NQO1 mRNA]
epigallocatechin gallate results in increased expression of NQO1 mRNA [epigallocatechin gallate co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of NQO1 mRNA; NFE2L2 protein affects the reaction [epigallocatechin gallate results in increased expression of NQO1 mRNA]
epigallocatechin gallate inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; epigallocatechin gallate inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; epigallocatechin gallate inhibits the reaction [SLCO1A2 protein results in increased uptake of Penicillins]; epigallocatechin gallate inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]
epigallocatechin gallate inhibits the reaction [TNF protein results in increased expression of CCL2 protein]; HMOX1 protein promotes the reaction [epigallocatechin gallate inhibits the reaction [TNF protein results in increased expression of CCL2 protein]]
epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA]; epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 protein]; epigallocatechin gallate inhibits the reaction [titanium dioxide results in increased expression of VCAM1 mRNA] epigallocatechin gallate results in decreased expression of VCAM1 mRNA
[alpha-naphthoflavone co-treated with 3,4,3',4'-tetrachlorobiphenyl] results in increased activity of AHR protein; epigallocatechin gallate inhibits the reaction [[alpha-naphthoflavone co-treated with 3,4,3',4'-tetrachlorobiphenyl] results in increased activity of AHR protein]; epigallocatechin gallate inhibits the reaction [alpha-naphthoflavone results in increased activity of AHR protein]
alpha-naphthoflavone inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 mRNA] alpha-naphthoflavone results in increased expression of CYP1A1 mRNA alpha-naphthoflavone results in decreased activity of CYP1A1 protein
beta-Naphthoflavone results in increased expression of CYP1A1 mRNA; beta-Naphthoflavone results in increased expression of CYP1A1 protein epigallocatechin gallate inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; epigallocatechin gallate inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]
Chlorogenic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of CXCL8 protein]; Chlorogenic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]
Chlorogenic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL6 protein]; Chlorogenic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]
CYP2A19 protein results in increased hydroxylation of coumarin 2-aminoacetophenone inhibits the reaction [[CYP2A19 protein results in increased hydroxylation of coumarin] which results in increased chemical synthesis of 7-hydroxycoumarin]; 2-aminoacetophenone inhibits the reaction [CYP2A19 protein results in increased hydroxylation of coumarin]; [CYP2A19 protein results in increased hydroxylation of coumarin] which results in increased chemical synthesis of 7-hydroxycoumarin; Skatole inhibits the reaction [[CYP2A19 protein results in increased hydroxylation of coumarin] which results in increased chemical synthesis of 7-hydroxycoumarin]; Skatole inhibits the reaction [CYP2A19 protein results in increased hydroxylation of coumarin]
daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of Penicillins]; daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]
[bisphenol A co-treated with fisetin] results in decreased expression of CYP11A1 mRNA; fisetin promotes the reaction [bisphenol A results in decreased expression of CYP11A1 mRNA]
bisphenol A promotes the reaction [fisetin inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]]; fisetin inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]; fisetin promotes the reaction [bisphenol A inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]]
bisphenol A promotes the reaction [fisetin results in decreased expression of HSD3B1 mRNA]; fisetin promotes the reaction [bisphenol A results in decreased expression of HSD3B1 mRNA]
[bisphenol A co-treated with fisetin] results in decreased expression of STAR mRNA; fisetin promotes the reaction [bisphenol A results in decreased expression of STAR mRNA]
Genistein inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]; Genistein inhibits the reaction [TNF protein results in increased expression of HIF1A protein]
Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of Penicillins]; Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]
kuwanon G results in decreased activity of PNLIP protein kuwanon G inhibits the reaction [PNLIP protein results in increased hydrolysis of 4-methylumbelliferyl oleate]
Masoprocol inhibits the reaction [Ritonavir results in decreased expression of NOS3 mRNA]; Masoprocol inhibits the reaction [Ritonavir results in decreased expression of NOS3 protein]
naringin inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; naringin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; naringin inhibits the reaction [SLCO1A2 protein results in increased uptake of Penicillins]; naringin inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]
caffeic acid phenethyl ester inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of PTGS2 protein]
[Heterocyclic Compounds results in decreased activity of NFE2L2 protein] inhibits the reaction [Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of HMOX1 mRNA]]; [Heterocyclic Compounds results in decreased activity of NFE2L2 protein] inhibits the reaction [Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of HMOX1 protein]]; Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of HMOX1 mRNA]; Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of HMOX1 protein]
[Heterocyclic Compounds results in decreased activity of NFE2L2 protein] inhibits the reaction [Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of HMOX1 mRNA]]; [Heterocyclic Compounds results in decreased activity of NFE2L2 protein] inhibits the reaction [Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of HMOX1 protein]]; [Heterocyclic Compounds results in decreased activity of NFE2L2 protein] inhibits the reaction [Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of NFE2L2 mRNA]]; [Heterocyclic Compounds results in decreased activity of NFE2L2 protein] inhibits the reaction [Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of NFE2L2 protein]]; [Heterocyclic Compounds results in decreased activity of NFE2L2 protein] inhibits the reaction [Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of NQO1 mRNA]]; [Heterocyclic Compounds results in decreased activity of NFE2L2 protein] inhibits the reaction [Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of NQO1 protein]]; Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of NFE2L2 mRNA]; Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of NFE2L2 protein]
[Heterocyclic Compounds results in decreased activity of NFE2L2 protein] inhibits the reaction [Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of NQO1 mRNA]]; [Heterocyclic Compounds results in decreased activity of NFE2L2 protein] inhibits the reaction [Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of NQO1 protein]]; Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of NQO1 mRNA]; Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of NQO1 protein]
Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of and results in increased phosphorylation of CAV1 protein]
Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased activity of CYP1A1 protein]; Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 protein]; Quercetin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein] Quercetin results in decreased activity of CYP1A1 protein
Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of VCAM1 mRNA]; Quercetin inhibits the reaction [Linoleic Acid results in increased expression of VCAM1 mRNA]
2-aminoacetophenone inhibits the reaction [[CYP2A19 protein results in increased hydroxylation of coumarin] which results in increased chemical synthesis of 7-hydroxycoumarin]; [CYP2A19 protein results in increased hydroxylation of coumarin] which results in increased chemical synthesis of 7-hydroxycoumarin; Skatole inhibits the reaction [[CYP2A19 protein results in increased hydroxylation of coumarin] which results in increased chemical synthesis of 7-hydroxycoumarin]
[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of BMP2 mRNA; [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of BMP2 protein; leptomycin B inhibits the reaction [Warfarin results in increased expression of BMP2 mRNA]; LRP6 protein affects the reaction [SOX5 protein inhibits the reaction [Warfarin results in increased expression of BMP2 mRNA]]; LRP6 protein affects the reaction [Warfarin results in increased expression of BMP2 mRNA]; SNAI2 protein promotes the reaction [[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of BMP2 mRNA]; SOX5 protein inhibits the reaction [Warfarin results in increased expression of BMP2 mRNA]
LRP6 protein affects the reaction [SOX5 protein inhibits the reaction [Warfarin results in increased expression of BMP2 mRNA]]; LRP6 protein affects the reaction [SOX5 protein inhibits the reaction [Warfarin results in increased expression of RUNX2 mRNA]]; LRP6 protein affects the reaction [Warfarin results in increased expression of BMP2 mRNA]; LRP6 protein affects the reaction [Warfarin results in increased expression of RUNX2 mRNA]; SOX5 protein promotes the reaction [Warfarin promotes the reaction [SOX9 protein binds to LRP6 promoter]]; SOX5 protein promotes the reaction [Warfarin results in increased expression of LRP6 protein]; Warfarin promotes the reaction [SOX9 protein binds to LRP6 promoter] Warfarin results in increased expression of LRP6 mRNA; Warfarin results in increased expression of LRP6 protein
[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of RUNX2 mRNA; [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of RUNX2 protein; Ammonium Chloride inhibits the reaction [SOX5 protein inhibits the reaction [Warfarin results in increased expression of RUNX2 mRNA]]; LRP6 protein affects the reaction [SOX5 protein inhibits the reaction [Warfarin results in increased expression of RUNX2 mRNA]]; LRP6 protein affects the reaction [Warfarin results in increased expression of RUNX2 mRNA]; SNAI2 protein promotes the reaction [[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of RUNX2 mRNA]; SNAI2 protein promotes the reaction [[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of RUNX2 protein]; SOX5 protein inhibits the reaction [Warfarin promotes the reaction [SOX9 protein binds to RUNX2 promoter]]; SOX5 protein inhibits the reaction [Warfarin results in increased expression of RUNX2 mRNA]; SOX5 protein inhibits the reaction [Warfarin results in increased expression of RUNX2 protein]; Warfarin promotes the reaction [SOX9 protein binds to RUNX2 promoter] Warfarin results in increased expression of RUNX2 mRNA; Warfarin results in increased expression of RUNX2 protein
[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of SNAI2 protein; SNAI2 protein promotes the reaction [[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of BMP2 mRNA]; SNAI2 protein promotes the reaction [[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of RUNX2 mRNA]; SNAI2 protein promotes the reaction [[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of RUNX2 protein]; SNAI2 protein promotes the reaction [TP53 protein results in increased susceptibility to Warfarin]; Warfarin promotes the reaction [TP53 protein binds to SNAI2 promoter]
Warfarin results in decreased expression of SOX5 mRNA Ammonium Chloride inhibits the reaction [SOX5 protein inhibits the reaction [Warfarin results in increased expression of RUNX2 mRNA]]; LRP6 protein affects the reaction [SOX5 protein inhibits the reaction [Warfarin results in increased expression of BMP2 mRNA]]; LRP6 protein affects the reaction [SOX5 protein inhibits the reaction [Warfarin results in increased expression of RUNX2 mRNA]]; SOX5 protein affects the reaction [Warfarin results in decreased expression of SOX9 mRNA]; SOX5 protein inhibits the reaction [Warfarin promotes the reaction [SOX9 protein binds to RUNX2 promoter]]; SOX5 protein inhibits the reaction [Warfarin results in decreased expression of and affects the localization of SOX9 protein]; SOX5 protein inhibits the reaction [Warfarin results in increased expression of BMP2 mRNA]; SOX5 protein inhibits the reaction [Warfarin results in increased expression of RUNX2 mRNA]; SOX5 protein inhibits the reaction [Warfarin results in increased expression of RUNX2 protein]; SOX5 protein promotes the reaction [Warfarin promotes the reaction [SOX9 protein binds to LRP6 promoter]]; SOX5 protein promotes the reaction [Warfarin results in increased expression of LRP6 protein]; Warfarin promotes the reaction [SOX5 protein binds to SOX9 promoter]; Warfarin results in decreased expression of and affects the localization of SOX5 protein
SOX5 protein affects the reaction [Warfarin results in decreased expression of SOX9 mRNA]; SOX5 protein inhibits the reaction [Warfarin promotes the reaction [SOX9 protein binds to RUNX2 promoter]]; SOX5 protein inhibits the reaction [Warfarin results in decreased expression of and affects the localization of SOX9 protein]; SOX5 protein promotes the reaction [Warfarin promotes the reaction [SOX9 protein binds to LRP6 promoter]]; Warfarin promotes the reaction [SOX5 protein binds to SOX9 promoter]; Warfarin promotes the reaction [SOX9 protein binds to LRP6 promoter]; Warfarin promotes the reaction [SOX9 protein binds to RUNX2 promoter]; Warfarin results in decreased expression of and affects the localization of SOX9 protein
TP53 protein results in increased susceptibility to Warfarin Warfarin results in increased expression of TP53 mRNA [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of BMP2 mRNA; [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of BMP2 protein; [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of CDKN1A protein; [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of EP300 protein; [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of RUNX2 mRNA; [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of RUNX2 protein; [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of SNAI2 protein; SNAI2 protein promotes the reaction [[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of BMP2 mRNA]; SNAI2 protein promotes the reaction [[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of RUNX2 mRNA]; SNAI2 protein promotes the reaction [[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of RUNX2 protein]; SNAI2 protein promotes the reaction [TP53 protein results in increased susceptibility to Warfarin]; Warfarin promotes the reaction [TP53 protein binds to SNAI2 promoter]; Warfarin results in increased expression of and results in decreased acetylation of TP53 protein
browse the term
