|
G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
Phenylhydrazines binds to and results in increased activity of AHR protein |
CTD |
PMID:11790108 |
|
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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|
G |
Ahsp |
alpha hemoglobin stabilizing protein |
increases expression |
EXP |
phenylhydrazine results in increased expression of AHSP mRNA |
CTD |
PMID:17082564 |
|
NCBI chr 1:182,879,901...182,885,508
Ensembl chr 1:182,880,076...182,885,506
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|
G |
Akap10 |
A-kinase anchoring protein 10 |
increases expression |
EXP |
phenylhydrazine results in increased expression of AKAP10 mRNA |
CTD |
PMID:17082564 |
|
NCBI chr10:46,545,464...46,608,768
Ensembl chr10:46,551,532...46,608,769
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|
G |
Alas2 |
5'-aminolevulinate synthase 2 |
increases expression |
EXP |
phenylhydrazine results in increased expression of ALAS2 mRNA |
CTD |
PMID:17082564 |
|
NCBI chr X:19,463,146...19,486,526
Ensembl chr X:19,463,171...19,486,519
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|
G |
Alb |
albumin |
multiple interactions |
EXP |
Folic Acid inhibits the reaction [phenylhydrazine inhibits the reaction [ALB protein binds to Bilirubin]]; phenylhydrazine inhibits the reaction [ALB protein binds to Bilirubin] |
CTD |
PMID:33788065 |
|
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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|
G |
Cbs |
cystathionine beta synthase |
decreases activity multiple interactions |
EXP |
phenylhydrazine results in decreased activity of CBS protein Folic Acid inhibits the reaction [phenylhydrazine results in decreased activity of CBS protein] |
CTD |
PMID:33788065 |
|
NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
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|
G |
Ccnd1 |
cyclin D1 |
multiple interactions affects expression decreases expression |
ISO |
Ascorbic Acid inhibits the reaction [phenylhydrazine results in decreased expression of CCND1 mRNA]; royal jelly inhibits the reaction [phenylhydrazine affects the expression of CCND1 mRNA] |
CTD |
PMID:30140404 PMID:35099105 |
|
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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|
G |
Cd7 |
Cd7 molecule |
decreases expression |
EXP |
phenylhydrazine results in decreased expression of CD7 mRNA |
CTD |
PMID:17698508 |
|
NCBI chr10:106,304,046...106,306,963
Ensembl chr10:106,304,056...106,306,967
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|
G |
Cd8a |
CD8 subunit alpha |
decreases expression |
EXP |
phenylhydrazine results in decreased expression of CD8A mRNA |
CTD |
PMID:17698508 |
|
NCBI chr 4:103,365,804...103,370,041
Ensembl chr 4:103,365,804...103,370,040
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|
G |
Ceacam4 |
CEA cell adhesion molecule 4 |
increases expression |
EXP |
phenylhydrazine results in increased expression of CEACAM10 mRNA |
CTD |
PMID:17082564 |
|
NCBI chr 1:80,376,667...80,382,943
Ensembl chr 1:80,376,648...80,382,915
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|
G |
Chchd6 |
coiled-coil-helix-coiled-coil-helix domain containing 6 |
increases expression |
EXP |
phenylhydrazine results in increased expression of CHCHD6 mRNA |
CTD |
PMID:17698508 |
|
NCBI chr 4:121,803,501...122,024,209
Ensembl chr 4:121,792,717...122,024,216
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|
G |
Creg1 |
cellular repressor of E1A-stimulated genes 1 |
increases expression |
EXP |
phenylhydrazine results in increased expression of CREG1 mRNA |
CTD |
PMID:17698508 |
|
NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308
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|
G |
Ctsb |
cathepsin B |
increases expression |
EXP |
phenylhydrazine results in increased expression of CTSB mRNA |
CTD |
PMID:17698508 |
|
NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
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|
G |
Ctsd |
cathepsin D |
increases expression |
EXP |
phenylhydrazine results in increased expression of CTSD mRNA |
CTD |
PMID:17698508 |
|
NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
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|
G |
Cul4a |
cullin 4A |
affects response to substance |
ISO |
CUL4A protein affects the susceptibility to phenylhydrazine |
CTD |
PMID:16467204 |
|
NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330
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|
G |
Cyp2c22 |
cytochrome P450, family 2, subfamily c, polypeptide 22 |
decreases expression |
EXP |
phenylhydrazine results in decreased expression of CYP2C22 mRNA |
CTD |
PMID:17082564 |
|
NCBI chr 1:238,991,698...239,031,323
Ensembl chr 1:238,991,610...239,021,738
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|
G |
Emb |
embigin |
increases expression |
EXP |
phenylhydrazine results in increased expression of EMB mRNA |
CTD |
PMID:17082564 |
|
NCBI chr 2:49,070,509...49,125,042
Ensembl chr 2:49,069,087...49,125,050
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|
G |
Epo |
erythropoietin |
increases expression |
EXP |
phenylhydrazine results in increased expression of EPO mRNA |
CTD |
PMID:22908232 |
|
NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
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|
G |
Epor |
erythropoietin receptor |
affects response to substance |
ISO |
EPOR gene mutant form affects the susceptibility to phenylhydrazine |
CTD |
PMID:16511603 |
|
NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257
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|
G |
Fabp4 |
fatty acid binding protein 4 |
increases expression |
EXP |
phenylhydrazine results in increased expression of FABP4 mRNA |
CTD |
PMID:17698508 |
|
NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
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G |
Fabp5 |
fatty acid binding protein 5 |
increases expression |
EXP |
phenylhydrazine results in increased expression of FABP5 mRNA |
CTD |
PMID:17698508 |
|
NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
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|
G |
Fcgr2b |
Fc gamma receptor 2B |
increases expression |
EXP |
phenylhydrazine results in increased expression of FCGR2B mRNA |
CTD |
PMID:17082564 |
|
NCBI chr13:83,191,253...83,207,776
Ensembl chr13:83,193,163...83,207,778
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|
G |
Flg |
filaggrin |
increases expression |
EXP |
phenylhydrazine results in increased expression of FLG mRNA |
CTD |
PMID:17082564 |
|
NCBI chr 2:178,888,688...178,912,731
|
|
G |
Frem2 |
FRAS1 related extracellular matrix 2 |
decreases expression |
EXP |
phenylhydrazine results in decreased expression of FREM2 mRNA |
CTD |
PMID:17082564 |
|
NCBI chr 2:137,602,784...137,740,785
Ensembl chr 2:137,602,784...137,740,785
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|
G |
Ftl1 |
ferritin light chain 1 |
increases expression |
EXP |
phenylhydrazine results in increased expression of FTL1 mRNA |
CTD |
PMID:17698508 |
|
NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725
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|
G |
G0s2 |
G0/G1switch 2 |
decreases expression |
EXP |
phenylhydrazine results in decreased expression of G0S2 mRNA |
CTD |
PMID:17082564 |
|
NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
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|
G |
Gcgr |
glucagon receptor |
increases expression |
EXP |
phenylhydrazine results in increased expression of GCGR mRNA |
CTD |
PMID:17698508 |
|
NCBI chr10:105,808,474...105,816,641
Ensembl chr10:105,808,473...105,816,640
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|
G |
Gfra1 |
GDNF family receptor alpha 1 |
increases expression |
EXP |
phenylhydrazine results in increased expression of GFRA1 mRNA |
CTD |
PMID:17698508 |
|
NCBI chr 1:257,315,682...257,552,004
Ensembl chr 1:257,321,742...257,551,473
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|
G |
Gpnmb |
glycoprotein nmb |
increases expression |
EXP |
phenylhydrazine results in increased expression of GPNMB mRNA |
CTD |
PMID:17082564 PMID:17698508 |
|
NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
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|
G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions increases activity |
ISO EXP |
SESN2 protein inhibits the reaction [phenylhydrazine results in increased activity of GPT protein] Folic Acid inhibits the reaction [phenylhydrazine results in increased activity of GPT protein] |
CTD |
PMID:31323261 PMID:33788065 |
|
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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|
G |
Gpx4 |
glutathione peroxidase 4 |
decreases expression |
ISO |
phenylhydrazine results in decreased expression of GPX4 protein |
CTD |
PMID:31323261 |
|
NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
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|
G |
Gsn |
gelsolin |
affects response to substance |
ISO |
GSN protein affects the susceptibility to phenylhydrazine |
CTD |
PMID:22271892 |
|
NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
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|
G |
Gzmk |
granzyme K |
decreases expression |
EXP |
phenylhydrazine results in decreased expression of GZMK mRNA |
CTD |
PMID:17698508 |
|
NCBI chr 2:44,840,811...44,848,829
Ensembl chr 2:44,840,811...44,848,894
|
|
G |
Hba-a1 |
hemoglobin alpha, adult chain 1 |
increases expression |
EXP |
phenylhydrazine results in increased expression of HBA-A1 mRNA |
CTD |
PMID:17082564 |
|
NCBI chr10:15,337,265...15,338,121
Ensembl chr10:15,307,815...15,338,392
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|
G |
Hbe2 |
hemoglobin, epsilon 2 |
increases expression |
EXP |
phenylhydrazine results in increased expression of HBE2 mRNA |
CTD |
PMID:17082564 |
|
NCBI chr 1:158,279,285...158,280,913
Ensembl chr 1:158,279,285...158,280,913
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|
G |
Hmox1 |
heme oxygenase 1 |
increases expression |
EXP |
phenylhydrazine results in increased expression of HMOX1 mRNA; phenylhydrazine results in increased expression of HMOX1 protein |
CTD |
PMID:17082564 PMID:17698508 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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|
G |
Lbp |
lipopolysaccharide binding protein |
increases expression |
EXP |
phenylhydrazine results in increased expression of LBP mRNA |
CTD |
PMID:17082564 |
|
NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586
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|
G |
Lgals3 |
galectin 3 |
increases expression |
EXP |
phenylhydrazine results in increased expression of LGALS3 mRNA |
CTD |
PMID:17082564 PMID:17698508 |
|
NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
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|
G |
Lgmn |
legumain |
increases expression |
EXP |
phenylhydrazine results in increased expression of LGMN mRNA |
CTD |
PMID:17698508 |
|
NCBI chr 6:121,544,048...121,582,495
Ensembl chr 6:121,544,053...121,582,480
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|
G |
Mt1 |
metallothionein 1 |
increases expression |
EXP |
phenylhydrazine results in increased expression of MT1A mRNA |
CTD |
PMID:17082564 |
|
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
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|
G |
Mthfr |
methylenetetrahydrofolate reductase |
multiple interactions decreases activity |
EXP |
Folic Acid inhibits the reaction [phenylhydrazine results in decreased activity of MTHFR protein] |
CTD |
PMID:33788065 |
|
NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
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|
G |
Mtr |
5-methyltetrahydrofolate-homocysteine methyltransferase |
decreases activity multiple interactions |
EXP |
phenylhydrazine results in decreased activity of MTR protein Folic Acid inhibits the reaction [phenylhydrazine results in decreased activity of MTR protein] |
CTD |
PMID:33788065 |
|
NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
|
|
G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
multiple interactions decreases expression |
ISO |
Ascorbic Acid inhibits the reaction [phenylhydrazine results in decreased expression of MYC mRNA]; royal jelly inhibits the reaction [phenylhydrazine results in decreased expression of MYC mRNA] |
CTD |
PMID:30140404 PMID:35099105 |
|
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
|
|
G |
Nat2 |
N-acetyltransferase 2 |
increases acetylation |
ISO |
NAT2 protein results in increased acetylation of phenylhydrazine |
CTD |
PMID:15627487 |
|
NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520
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|
G |
Nck2 |
NCK adaptor protein 2 |
decreases expression |
EXP |
phenylhydrazine results in decreased expression of NCK2 mRNA |
CTD |
PMID:17082564 |
|
NCBI chr 9:45,713,979...45,840,330
Ensembl chr 9:45,714,883...45,840,307
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|
G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
increases activity |
ISO |
phenylhydrazine results in increased activity of NFE2L2 protein |
CTD |
PMID:30114225 PMID:30203046 |
|
NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
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|
G |
Nppb |
natriuretic peptide B |
multiple interactions increases expression |
EXP |
Doxorubicin inhibits the reaction [phenylhydrazine results in increased expression of NPPB mRNA] |
CTD |
PMID:22908232 |
|
NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
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|
G |
Npy |
neuropeptide Y |
increases expression |
EXP |
phenylhydrazine results in increased expression of NPY mRNA |
CTD |
PMID:17082564 |
|
NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
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|
G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
increases expression |
ISO |
phenylhydrazine results in increased expression of NR1I3 mRNA |
CTD |
PMID:25949234 |
|
NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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|
G |
Orc1 |
origin recognition complex, subunit 1 |
increases expression |
EXP |
phenylhydrazine results in increased expression of ORC1 mRNA |
CTD |
PMID:17698508 |
|
NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375
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|
G |
Plscr1 |
phospholipid scramblase 1 |
increases expression |
EXP |
phenylhydrazine results in increased expression of PLSCR1 mRNA |
CTD |
PMID:17082564 |
|
NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:92,784,356...92,804,692
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|
G |
Psmd6 |
proteasome 26S subunit, non-ATPase 6 |
increases expression |
EXP |
phenylhydrazine results in increased expression of PSMD6 mRNA |
CTD |
PMID:17082564 |
|
NCBI chr15:11,102,208...11,112,180
Ensembl chr15:11,102,180...11,205,620
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|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases expression |
ISO |
Plant Extracts inhibits the reaction [phenylhydrazine results in increased expression of PTGS2 protein]; SESN2 protein inhibits the reaction [phenylhydrazine results in increased expression of PTGS2 protein] |
CTD |
PMID:30626086 PMID:31323261 |
|
NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
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G |
Ptpmt1 |
protein tyrosine phosphatase, mitochondrial 1 |
increases expression |
EXP |
phenylhydrazine results in increased expression of PTPMT1 mRNA |
CTD |
PMID:17698508 |
|
NCBI chr 3:76,889,922...76,899,427
Ensembl chr 3:76,889,922...76,899,427
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|
G |
RGD1306195 |
similar to RAN protein |
increases expression |
EXP |
phenylhydrazine results in increased expression of RGD1306195 mRNA |
CTD |
PMID:17698508 |
|
NCBI chr 5:54,456,005...54,457,381
Ensembl chr 5:54,455,893...54,457,677
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|
G |
Rhd |
Rh blood group, D antigen |
increases expression |
EXP |
phenylhydrazine results in increased expression of RHD mRNA |
CTD |
PMID:17082564 |
|
NCBI chr 5:147,087,479...147,121,716
Ensembl chr 5:147,087,518...147,121,715
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|
G |
Ripk3 |
receptor-interacting serine-threonine kinase 3 |
increases expression |
EXP |
phenylhydrazine results in increased expression of RIPK3 mRNA |
CTD |
PMID:17082564 |
|
NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
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|
G |
RT1-Bb |
RT1 class II, locus Bb |
decreases expression |
EXP |
phenylhydrazine results in decreased expression of RT1-BB mRNA |
CTD |
PMID:17698508 |
|
NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
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|
G |
S100a8 |
S100 calcium binding protein A8 |
increases expression |
EXP |
phenylhydrazine results in increased expression of S100A8 mRNA |
CTD |
PMID:17082564 |
|
NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
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|
G |
S100a9 |
S100 calcium binding protein A9 |
increases expression |
EXP |
phenylhydrazine results in increased expression of S100A9 mRNA |
CTD |
PMID:17082564 |
|
NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
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|
G |
Serpina3n |
serine (or cysteine) peptidase inhibitor, clade A, member 3N |
increases expression |
EXP |
phenylhydrazine results in increased expression of SERPINA3N mRNA |
CTD |
PMID:17698508 |
|
NCBI chr 6:123,323,632...123,331,166
Ensembl chr 6:123,323,629...123,332,433
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|
G |
Sesn2 |
sestrin 2 |
multiple interactions |
ISO |
SESN2 protein inhibits the reaction [phenylhydrazine results in increased activity of GPT protein]; SESN2 protein inhibits the reaction [phenylhydrazine results in increased expression of PTGS2 protein] |
CTD |
PMID:31323261 |
|
NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
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|
G |
Slc39a14 |
solute carrier family 39 member 14 |
increases expression |
EXP |
phenylhydrazine results in increased expression of SLC39A14 mRNA |
CTD |
PMID:17082564 |
|
NCBI chr15:45,376,806...45,423,549
Ensembl chr15:45,376,917...45,423,524
|
|
G |
Slc40a1 |
solute carrier family 40 member 1 |
increases expression |
EXP |
phenylhydrazine results in increased expression of SLC40A1 mRNA |
CTD |
PMID:17082564 |
|
NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
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|
G |
Spata48 |
spermatogenesis associated 48 |
increases expression |
EXP |
phenylhydrazine results in increased expression of SPATA48 mRNA |
CTD |
PMID:17698508 |
|
NCBI chr14:86,030,577...86,085,644
Ensembl chr14:86,030,655...86,085,644
|
|
G |
Spink1 |
serine peptidase inhibitor, Kazal type 1 |
increases expression |
EXP |
phenylhydrazine results in increased expression of SPINK1 mRNA |
CTD |
PMID:17082564 |
|
NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
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|
G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
phenylhydrazine analog inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein] |
CTD |
PMID:26549477 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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|
G |
Tnfrsf17 |
TNF receptor superfamily member 17 |
decreases expression |
EXP |
phenylhydrazine results in decreased expression of TNFRSF17 mRNA |
CTD |
PMID:17698508 |
|
NCBI chr10:4,301,023...4,306,889
Ensembl chr10:4,301,038...4,306,788
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|
G |
Trib3 |
tribbles pseudokinase 3 |
increases expression |
EXP |
phenylhydrazine results in increased expression of TRIB3 mRNA |
CTD |
PMID:17082564 |
|
NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
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|
G |
Ucp2 |
uncoupling protein 2 |
affects response to substance |
ISO |
UCP2 protein affects the susceptibility to phenylhydrazine |
CTD |
PMID:18687678 |
|
NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
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|
G |
Vcam1 |
vascular cell adhesion molecule 1 |
increases expression |
EXP |
phenylhydrazine results in increased expression of VCAM1 mRNA |
CTD |
PMID:17082564 |
|
NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
|
|
G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions increases expression |
EXP |
Doxorubicin inhibits the reaction [phenylhydrazine results in increased expression of VEGFA mRNA] |
CTD |
PMID:22908232 |
|
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
|
|
G |
Zbtb44 |
zinc finger and BTB domain containing 44 |
decreases expression |
EXP |
phenylhydrazine results in decreased expression of ZBTB44 mRNA |
CTD |
PMID:17082564 |
|
NCBI chr 8:29,466,055...29,524,027
Ensembl chr 8:29,466,352...29,518,163
|
|