CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: pesticide synergist
Accession: CHEBI:25943
browse the term
Definition: A substance that increases the efficacy of a pesticide.
Synonyms: related_synonym: pesticide synergists
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Aaas
aladin WD repeat nucleoporin
increases expression
EXP
Piperonyl Butoxide results in increased expression of AAAS mRNA
CTD
PMID:22484513
NCBI chr 7:133,464,315...133,483,961
Ensembl chr 7:133,464,315...133,483,961
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Aadac
arylacetamide deacetylase
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of AADAC mRNA
CTD
PMID:22484513
NCBI chr 2:144,163,436...144,186,086
Ensembl chr 2:144,135,319...144,174,734
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Abcb1a
ATP binding cassette subfamily B member 1A
increases expression
EXP
Piperonyl Butoxide results in increased expression of ABCB1A mRNA
CTD
PMID:22484513
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Abcb6
ATP binding cassette subfamily B member 6
increases expression
EXP
Piperonyl Butoxide results in increased expression of ABCB6 mRNA
CTD
PMID:22484513
NCBI chr 9:76,668,554...76,677,263
Ensembl chr 9:76,668,554...76,676,924
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Abcc2
ATP binding cassette subfamily C member 2
increases expression
ISO
Piperonyl Butoxide results in increased expression of ABCC2 mRNA
CTD
PMID:19690152
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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Abcc3
ATP binding cassette subfamily C member 3
multiple interactions increases expression
ISO EXP
[Piperonyl Butoxide co-treated with Diethylnitrosamine] results in increased expression of ABCC3 mRNA Piperonyl Butoxide results in increased expression of ABCC3 mRNA [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of ABCC3 mRNA
CTD
PMID:17498859 PMID:18648771 PMID:19690152 PMID:22484513
NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
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Abcc4
ATP binding cassette subfamily C member 4
increases expression multiple interactions
ISO
Piperonyl Butoxide results in increased expression of ABCC4 mRNA [Piperonyl Butoxide co-treated with Diethylnitrosamine] results in increased expression of ABCC4 mRNA
CTD
PMID:19690152
NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
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Abr
ABR activator of RhoGEF and GTPase
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of ABR gene
CTD
PMID:23968726
NCBI chr10:61,262,516...61,461,331
Ensembl chr10:61,262,516...61,461,505
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Aco1
aconitase 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of ACO1 mRNA
CTD
PMID:15890375
NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
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Acox1
acyl-CoA oxidase 1
multiple interactions
ISO
[NR1I2 gene mutant form affects the susceptibility to Piperonyl Butoxide] which results in increased expression of ACOX1 mRNA; [NR1I3 gene mutant form affects the susceptibility to Piperonyl Butoxide] which results in increased expression of ACOX1 mRNA
CTD
PMID:32320717
NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
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Actn3
actinin alpha 3
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of ACTN3 gene
CTD
PMID:23968726
NCBI chr 1:202,159,081...202,175,012
Ensembl chr 1:202,159,082...202,175,012
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Ahr
aryl hydrocarbon receptor
multiple interactions increases expression decreases activity
ISO EXP
[Piperonyl Butoxide co-treated with Diethylnitrosamine] results in increased expression of AHR mRNA Piperonyl Butoxide results in increased expression of AHR mRNA Piperonyl Butoxide results in decreased activity of AHR protein
CTD
PMID:18544911 PMID:19690152 PMID:30203046
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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Aig1
androgen-induced 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of AIG1 mRNA
CTD
PMID:22484513
NCBI chr 1:8,046,430...8,269,276
Ensembl chr 1:8,046,430...8,269,084
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Akr7a3
aldo-keto reductase family 7 member A3
increases expression multiple interactions
EXP
Piperonyl Butoxide results in increased expression of AKR7A3 mRNA Triterpenes promotes the reaction [Piperonyl Butoxide results in increased expression of AKR7A3 mRNA]
CTD
PMID:18544911 PMID:22484513
NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
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Aldh1a1
aldehyde dehydrogenase 1 family, member A1
increases expression
EXP
Piperonyl Butoxide results in increased expression of ALDH1A1 mRNA
CTD
PMID:22484513
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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Ankhd1
ankyrin repeat and KH domain containing 1
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of ANKHD1-EIF4EBP3 mRNA
CTD
PMID:22484513
NCBI chr18:28,161,882...28,260,917
Ensembl chr18:28,162,311...28,268,024
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Anxa7
annexin A7
increases expression
EXP
Piperonyl Butoxide results in increased expression of ANXA7 mRNA
CTD
PMID:22484513
NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385
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Ap1m1
adaptor related protein complex 1 subunit mu 1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of AP1M1 gene
CTD
PMID:23968726
NCBI chr16:17,586,886...17,602,410
Ensembl chr16:17,584,730...17,602,403
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Apex1
apurinic/apyrimidinic endodeoxyribonuclease 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of APEX1 mRNA
CTD
PMID:15890375
NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
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Apoa4
apolipoprotein A4
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of APOA4 mRNA
CTD
PMID:22484513
NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
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App
amyloid beta precursor protein
increases expression
EXP
Piperonyl Butoxide results in increased expression of APP mRNA
CTD
PMID:22484513
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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Aqp9
aquaporin 9
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of AQP9 mRNA
CTD
PMID:22484513
NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
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Ar
androgen receptor
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of AR mRNA
CTD
PMID:22467018
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Arap1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of ARAP1 gene
CTD
PMID:23968726
NCBI chr 1:155,748,622...155,814,186
Ensembl chr 1:155,748,652...155,814,184
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Arpp19
cAMP-regulated phosphoprotein 19
increases expression
EXP
Piperonyl Butoxide results in increased expression of ARPP19 mRNA
CTD
PMID:22484513
NCBI chr 8:75,779,640...75,802,474
Ensembl chr 8:75,779,523...75,802,452 Ensembl chr 8:75,779,523...75,802,452
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Arsb
arylsulfatase B
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of ARSB gene
CTD
PMID:23968726
NCBI chr 2:25,002,210...25,162,675
Ensembl chr 2:25,002,346...25,162,671
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Art1
ADP-ribosyltransferase 1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of ART1 gene
CTD
PMID:23968726
NCBI chr 1:156,478,096...156,487,172
Ensembl chr 1:156,482,621...156,487,172
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Atf2
activating transcription factor 2
multiple interactions increases expression increases phosphorylation
ISO
[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of ATF2 mRNA Piperonyl Butoxide results in increased expression of ATF2 mRNA Piperonyl Butoxide results in increased phosphorylation of ATF2 protein
CTD
PMID:18228000 PMID:19690152
NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
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Atf3
activating transcription factor 3
multiple interactions increases expression
ISO EXP
[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of ATF3 mRNA Piperonyl Butoxide results in increased expression of ATF3 mRNA
CTD
PMID:15890375 PMID:19690152
NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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Atp5f1b
ATP synthase F1 subunit beta
multiple interactions
EXP
[Piperonyl Butoxide co-treated with beta-Naphthoflavone] results in decreased expression of ATP5F1B protein
CTD
PMID:28903497
NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
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Aurkb
aurora kinase B
increases expression
EXP
Piperonyl Butoxide results in increased expression of AURKB protein
CTD
PMID:23411599
NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
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Bag4
BAG cochaperone 4
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of BAG4 gene
CTD
PMID:23968726
NCBI chr16:66,288,678...66,305,893
Ensembl chr16:66,288,678...66,308,663
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Bahd1
bromo adjacent homology domain containing 1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of BAHD1 gene
CTD
PMID:23968726
NCBI chr 3:105,891,207...105,914,414
Ensembl chr 3:105,892,478...105,914,410
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Bax
BCL2 associated X, apoptosis regulator
increases expression
EXP
Piperonyl Butoxide results in increased expression of BAX mRNA
CTD
PMID:15890375
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcor
BCL6 co-repressor
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of BCOR gene
CTD
PMID:23968726
NCBI chr X:10,609,756...10,729,613
Ensembl chr X:10,687,732...10,729,613
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Bhmt
betaine-homocysteine S-methyltransferase
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of BHMT mRNA
CTD
PMID:22484513
NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
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Bpifb4
BPI fold containing family B, member 4
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of BPIFB4 gene
CTD
PMID:23968726
NCBI chr 3:142,423,571...142,448,044
Ensembl chr 3:142,400,976...142,448,044
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Btg2
BTG anti-proliferation factor 2
increases expression
EXP
Piperonyl Butoxide results in increased expression of BTG2 mRNA
CTD
PMID:15890375
NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
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Bub1
BUB1 mitotic checkpoint serine/threonine kinase
increases expression
ISO
Piperonyl Butoxide results in increased expression of BUB1 mRNA
CTD
PMID:30572783
NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
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C1qtnf3
C1q and TNF related 3
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of C1QTNF3 gene
CTD
PMID:23968726
NCBI chr 2:59,917,099...59,939,519
Ensembl chr 2:59,917,188...59,939,433
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C1s
complement C1s
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of C1S mRNA
CTD
PMID:22484513
NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303
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Camk2a
calcium/calmodulin-dependent protein kinase II alpha
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CAMK2A gene
CTD
PMID:23968726
NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
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Capg
capping actin protein, gelsolin like
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CAPG gene
CTD
PMID:23968726
NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856
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Cars1
cysteinyl-tRNA synthetase 1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CARS1 gene
CTD
PMID:23968726
NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941
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Caskin1
CASK interacting protein 1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CASKIN1 gene
CTD
PMID:23968726
NCBI chr10:13,512,684...13,533,380
Ensembl chr10:13,513,465...13,533,377
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Casp3
caspase 3
increases expression
EXP
Piperonyl Butoxide results in increased expression of CASP3 mRNA
CTD
PMID:22484513
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Cbarp
CACN subunit beta associated regulatory protein
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CBARP gene
CTD
PMID:23968726
NCBI chr 7:9,566,637...9,575,204
Ensembl chr 7:9,566,364...9,575,204
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Ccdc33
coiled-coil domain containing 33
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CCDC33 gene
CTD
PMID:23968726
NCBI chr 8:58,434,798...58,534,338
Ensembl chr 8:58,435,661...58,534,370
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Ccnb1
cyclin B1
increases expression
EXP
Piperonyl Butoxide results in increased expression of CCNB1 mRNA
CTD
PMID:15890375 PMID:22484513
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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Ccnb2
cyclin B2
increases expression
ISO
Piperonyl Butoxide results in increased expression of CCNB2 mRNA
CTD
PMID:30572783
NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
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Ccnc
cyclin C
decreases expression
ISO
Piperonyl Butoxide results in decreased expression of CCNC mRNA
CTD
PMID:17014948
NCBI chr 5:35,266,828...35,284,943
Ensembl chr 5:35,266,823...35,296,584
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Ccnd1
cyclin D1
multiple interactions increases expression
ISO EXP
[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of CCND1 mRNA Piperonyl Butoxide results in increased expression of CCND1 mRNA
CTD
PMID:15890375 PMID:17014948 PMID:19690152 PMID:20101389
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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Ccng1
cyclin G1
increases expression
ISO EXP
Piperonyl Butoxide results in increased expression of CCNG1 mRNA
CTD
PMID:15890375 PMID:19690152
NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
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Cct3
chaperonin containing TCP1 subunit 3
increases expression
EXP
Piperonyl Butoxide results in increased expression of CCT3 mRNA
CTD
PMID:15890375
NCBI chr 2:173,765,701...173,790,353
Ensembl chr 2:173,765,698...173,790,757
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Cct5
chaperonin containing TCP1 subunit 5
increases expression
EXP
Piperonyl Butoxide results in increased expression of CCT5 mRNA
CTD
PMID:22484513
NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
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Cd36
CD36 molecule
increases expression
EXP
Piperonyl Butoxide results in increased expression of CD36 mRNA
CTD
PMID:22467018
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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Cd37
CD37 molecule
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CD37 gene
CTD
PMID:23968726
NCBI chr 1:95,719,171...95,724,662
Ensembl chr 1:95,719,190...95,724,648
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Cdc20
cell division cycle 20
increases expression
EXP
Piperonyl Butoxide results in increased expression of CDC20 mRNA
CTD
PMID:15890375
NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
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Cdc34
cell division cycle 34, ubiqiutin conjugating enzyme
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CDC34 gene
CTD
PMID:23968726
NCBI chr 7:10,017,588...10,023,586
Ensembl chr 7:10,017,588...10,023,186
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Cdc42bpb
CDC42 binding protein kinase beta
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CDC42BPB gene
CTD
PMID:23968726
NCBI chr 6:130,333,712...130,416,631
Ensembl chr 6:130,333,712...130,416,377
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Cdc42se1
CDC42 small effector 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of CDC42SE1 mRNA
CTD
PMID:22484513
NCBI chr 2:182,805,691...182,813,520
Ensembl chr 2:182,804,925...182,814,028
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Cdk1
cyclin-dependent kinase 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of CDK1 mRNA; Piperonyl Butoxide results in increased expression of CDK1 protein
CTD
PMID:15890375 PMID:23411599
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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Cdk16
cyclin-dependent kinase 16
increases expression
EXP
Piperonyl Butoxide results in increased expression of CDK16 mRNA
CTD
PMID:15890375
NCBI chr X:1,492,814...1,504,309
Ensembl chr X:1,492,814...1,504,148
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Cdk4
cyclin-dependent kinase 4
increases expression
EXP
Piperonyl Butoxide results in increased expression of CDK4 mRNA
CTD
PMID:15890375
NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
EXP
Piperonyl Butoxide results in increased expression of CDKN1A mRNA; Piperonyl Butoxide results in increased expression of CDKN1A protein
CTD
PMID:15890375 PMID:23411599
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Cdkn3
cyclin-dependent kinase inhibitor 3
increases expression
EXP
Piperonyl Butoxide results in increased expression of CDKN3 mRNA
CTD
PMID:22484513
NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
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Cdo1
cysteine dioxygenase type 1
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of CDO1 mRNA
CTD
PMID:22484513
NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
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Ces2h
carboxylesterase 2H
increases expression
EXP
Piperonyl Butoxide results in increased expression of CES2 mRNA
CTD
PMID:22484513
NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
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Cgn
cingulin
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CGN gene
CTD
PMID:23968726
NCBI chr 2:182,308,389...182,335,747
Ensembl chr 2:182,308,714...182,334,645
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Cgref1
cell growth regulator with EF hand domain 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of CGREF1 mRNA
CTD
PMID:15890375
NCBI chr 6:25,431,846...25,443,853
Ensembl chr 6:25,431,799...25,443,852
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Cgrrf1
cell growth regulator with ring finger domain 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of CGRRF1 mRNA
CTD
PMID:15890375
NCBI chr15:20,088,564...20,109,042
Ensembl chr15:20,088,571...20,109,037
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Champ1
chromosome alignment maintaining phosphoprotein 1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CHAMP1 gene
CTD
PMID:23968726
NCBI chr16:75,733,958...75,744,931
Ensembl chr16:75,733,805...75,744,984
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Chchd6
coiled-coil-helix-coiled-coil-helix domain containing 6
increases expression
EXP
Piperonyl Butoxide results in increased expression of CHCHD6 mRNA
CTD
PMID:22484513
NCBI chr 4:121,803,501...122,024,209
Ensembl chr 4:121,792,717...122,024,216
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Chst12
carbohydrate sulfotransferase 12
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CHST12 gene
CTD
PMID:23968726
NCBI chr12:14,110,631...14,129,099
Ensembl chr12:14,110,393...14,129,057
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Cidea
cell death-inducing DFFA-like effector a
increases expression
EXP
Piperonyl Butoxide results in increased expression of CIDEA mRNA
CTD
PMID:22484513
NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481
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Cldn15
claudin 15
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CLDN15 gene
CTD
PMID:23968726
NCBI chr12:19,698,167...19,708,419
Ensembl chr12:19,698,337...19,706,819
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Cltb
clathrin, light chain B
increases expression
EXP
Piperonyl Butoxide results in increased expression of CLTB mRNA
CTD
PMID:22484513
NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169
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Cmtm6
CKLF-like MARVEL transmembrane domain containing 6
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the expression of and affects the localization of CMTM6 protein; [Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CMTM6 gene
CTD
PMID:23968726
NCBI chr 8:114,422,934...114,441,034
Ensembl chr 8:114,422,921...114,441,033
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Col26a1
collagen type XXVI alpha 1 chain
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of COL26A1 gene
CTD
PMID:23968726
NCBI chr12:19,792,693...19,938,556
Ensembl chr12:19,792,728...19,938,556
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Commd3
COMM domain containing 3
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of COMMD3 gene
CTD
PMID:23968726
NCBI chr17:81,327,444...81,331,191
Ensembl chr17:81,327,405...81,331,177
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Coq8a
coenzyme Q8A
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of COQ8A mRNA
CTD
PMID:22484513
NCBI chr13:91,904,731...91,933,588
Ensembl chr13:91,904,739...91,931,431
G
Cpt2
carnitine palmitoyltransferase 2
increases expression
EXP
Piperonyl Butoxide results in increased expression of CPT2 mRNA
CTD
PMID:22484513
NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
G
Cr1l
complement C3b/C4b receptor 1 like
increases expression
EXP
Piperonyl Butoxide results in increased expression of CR1L mRNA
CTD
PMID:15890375
NCBI chr13:106,606,952...106,660,442
Ensembl chr13:106,574,858...106,660,445
G
Creld2
cysteine-rich with EGF-like domains 2
increases expression
EXP
Piperonyl Butoxide results in increased expression of CRELD2 mRNA
CTD
PMID:22484513
NCBI chr 7:119,909,626...119,916,556
Ensembl chr 7:119,909,633...119,916,543
G
Cryl1
crystallin, lambda 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of CRYL1 mRNA
CTD
PMID:22484513
NCBI chr15:31,427,011...31,545,997
Ensembl chr15:31,427,054...31,545,997
G
Cstb
cystatin B
increases expression
EXP
Piperonyl Butoxide results in increased expression of CSTB mRNA
CTD
PMID:15890375
NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526
G
Ctsd
cathepsin D
increases expression
EXP
Piperonyl Butoxide results in increased expression of CTSD mRNA
CTD
PMID:15890375 PMID:22484513
NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
G
Cxcl10
C-X-C motif chemokine ligand 10
increases expression
EXP
Piperonyl Butoxide results in increased expression of CXCL10 mRNA
CTD
PMID:15890375
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
G
Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of CYP17A1 mRNA
CTD
PMID:22484513
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression multiple interactions affects expression
ISO EXP
Piperonyl Butoxide results in increased expression of CYP1A1 mRNA; Piperonyl Butoxide results in increased expression of CYP1A1 protein [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of CYP1A1 mRNA; [Permethrin co-treated with Piperonyl Butoxide] results in increased expression of CYP1A1 mRNA; Piperonyl Butoxide affects the reaction [Phenobarbital affects the expression of CYP1A1 mRNA] [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of CYP1A1 mRNA; [Piperonyl Butoxide co-treated with Cycloheximide] results in increased expression of CYP1A1 mRNA Piperonyl Butoxide affects the expression of CYP1A1 mRNA
CTD
PMID:8722114 PMID:9233375 PMID:11377398 PMID:17014948 PMID:17498859 PMID:18648771 PMID:19690152 PMID:20101389 PMID:20735435 PMID:21784029 PMID:22008526 PMID:24025784 More...
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
G
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
increases expression multiple interactions
ISO EXP
Piperonyl Butoxide results in increased expression of CYP1A2 mRNA; Piperonyl Butoxide results in increased expression of CYP1A2 protein Triterpenes promotes the reaction [Piperonyl Butoxide results in increased expression of CYP1A2 mRNA]
CTD
PMID:8722114 PMID:9233375 PMID:18544911 PMID:20735435 PMID:21784029 PMID:30572783 PMID:32320717 More...
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
G
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
increases expression
ISO
Piperonyl Butoxide results in increased expression of CYP1B1 mRNA
CTD
PMID:10402558
NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
G
Cyp26a1
cytochrome P450, family 26, subfamily a, polypeptide 1
increases expression
ISO
Piperonyl Butoxide results in increased expression of CYP26A1 mRNA
CTD
PMID:30572783
NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
G
Cyp2b1
cytochrome P450, family 2, subfamily b, polypeptide 1
multiple interactions increases expression
EXP
[Permethrin co-treated with Piperonyl Butoxide] results in increased expression of CYP2B1 mRNA; Piperonyl Butoxide inhibits the reaction [Permethrin results in increased expression of CYP2B1 mRNA] Piperonyl Butoxide results in increased expression of CYP2B1 mRNA
CTD
PMID:11377398 PMID:20735435
NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
G
Cyp2b2
cytochrome P450, family 2, subfamily b, polypeptide 2
affects expression multiple interactions
EXP
Piperonyl Butoxide affects the expression of CYP2B2 mRNA Piperonyl Butoxide affects the reaction [Phenobarbital affects the expression of CYP2B2 mRNA]
CTD
PMID:24025784
NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
G
Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
increases expression multiple interactions
ISO
Piperonyl Butoxide results in increased expression of CYP2B10 mRNA [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of CYP2B10 mRNA
CTD
PMID:17014948 PMID:19690152 PMID:20101389 PMID:22972318 PMID:23531792 PMID:26558459 PMID:32320717 More...
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
G
Cyp2j4
cytochrome P450, family 2, subfamily j, polypeptide 4
increases expression
EXP
Piperonyl Butoxide results in increased expression of CYP2J4 mRNA
CTD
PMID:22484513
NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
G
Cyp7b1
cytochrome P450 family 7 subfamily B member 1
decreases expression
ISO
Piperonyl Butoxide results in decreased expression of CYP7B1 mRNA
CTD
PMID:30572783
NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
G
Cyp8b1
cytochrome P450 family 8 subfamily B member 1
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of CYP8B1 mRNA
CTD
PMID:22484513
NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
G
Ddah1
dimethylarginine dimethylaminohydrolase 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of DDAH1 mRNA
CTD
PMID:15890375
NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339
G
Ddx21
DExD-box helicase 21
increases expression
EXP
Piperonyl Butoxide results in increased expression of DDX21 mRNA
CTD
PMID:15890375
NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543
G
Ddx39a
DExD-box helicase 39A
increases expression
EXP
Piperonyl Butoxide results in increased expression of DDX39A mRNA
CTD
PMID:22484513
NCBI chr19:24,418,743...24,427,422
Ensembl chr19:24,418,114...24,426,954
G
Decr1
2,4-dienoyl-CoA reductase 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of DECR1 mRNA
CTD
PMID:22484513
NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
G
Defb17
defensin beta 17
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of DEFB41 gene
CTD
PMID:23968726
NCBI chr 9:20,880,246...20,883,875
G
Dennd4a
DENN domain containing 4A
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of DENND4A gene
CTD
PMID:23968726
NCBI chr 8:65,322,920...65,436,331
Ensembl chr 8:65,322,941...65,436,330
G
Dixdc1
DIX domain containing 1
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of DIXDC1 mRNA
CTD
PMID:22484513
NCBI chr 8:51,007,835...51,081,191
Ensembl chr 8:51,007,838...51,081,090
G
Dkc1
dyskerin pseudouridine synthase 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of DKC1 mRNA
CTD
PMID:15890375
G
Dmgdh
dimethylglycine dehydrogenase
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of DMGDH mRNA
CTD
PMID:22484513
NCBI chr 2:24,912,600...24,987,533
Ensembl chr 2:24,912,578...24,987,528
G
Dmrt1
doublesex and mab-3 related transcription factor 1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of DMRT1 gene
CTD
PMID:23968726
NCBI chr 1:223,142,859...223,241,333
Ensembl chr 1:223,142,859...223,241,333
G
Dnmt1
DNA methyltransferase 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of DNMT1 mRNA
CTD
PMID:22484513
NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
G
Dpyd
dihydropyrimidine dehydrogenase
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of DPYD mRNA
CTD
PMID:15890375
NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
G
Dusp6
dual specificity phosphatase 6
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of DUSP6 mRNA
CTD
PMID:15890375 PMID:22484513
NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
G
Dut
deoxyuridine triphosphatase
increases expression
EXP
Piperonyl Butoxide results in increased expression of DUT mRNA
CTD
PMID:15890375 PMID:22484513
NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771
G
Dynll1
dynein light chain LC8-type 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of DYNLL1 mRNA
CTD
PMID:22484513
NCBI chr12:41,312,365...41,316,157
Ensembl chr12:41,312,367...41,314,741
G
E2f1
E2F transcription factor 1
multiple interactions
ISO
[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of E2F1 mRNA
CTD
PMID:20101389
NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
G
Ech1
enoyl-CoA hydratase 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of ECH1 mRNA
CTD
PMID:22484513
NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
G
Eef1g
eukaryotic translation elongation factor 1 gamma
increases expression
EXP
Piperonyl Butoxide results in increased expression of EEF1G mRNA
CTD
PMID:15890375
NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382
G
Eef2
eukaryotic translation elongation factor 2
increases expression
EXP
Piperonyl Butoxide results in increased expression of EEF2 mRNA
CTD
PMID:15890375
NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
G
Efna3
ephrin A3
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of EFNA3 gene
CTD
PMID:23968726
NCBI chr 2:174,729,192...174,738,111
Ensembl chr 2:174,729,764...174,738,736
G
Egf
epidermal growth factor
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of EGF mRNA
CTD
PMID:22484513
NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
G
Egfr
epidermal growth factor receptor
multiple interactions
ISO
[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in decreased expression of EGFR mRNA
CTD
PMID:20101389
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
G
Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of EIF4EBP1 mRNA
CTD
PMID:15890375
NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
G
Epb41
erythrocyte membrane protein band 4.1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of EPB41 gene
CTD
PMID:23968726
NCBI chr 5:144,110,010...144,264,037
Ensembl chr 5:144,111,906...144,237,821
G
Ephx1
epoxide hydrolase 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of EPHX1 mRNA
CTD
PMID:15890375 PMID:22484513
NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
G
Esr1
estrogen receptor 1
decreases expression
EXP
[Piperonyl Butoxide results in decreased expression of ESR1 mRNA] which results in decreased expression of LIFR mRNA; Piperonyl Butoxide results in decreased expression of ESR1 mRNA
CTD
PMID:22467018
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
G
Exoc2
exocyst complex component 2
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of EXOC2 gene
CTD
PMID:23968726
NCBI chr17:33,506,289...33,698,246
Ensembl chr17:33,506,338...33,693,289
G
Extl1
exostosin-like glycosyltransferase 1
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of EXTL1 mRNA
CTD
PMID:22484513
NCBI chr 5:146,573,911...146,589,115
Ensembl chr 5:146,573,912...146,589,115
G
Fabp5
fatty acid binding protein 5
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of FABP5 mRNA
CTD
PMID:22484513
NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
G
Fam162a
family with sequence similarity 162, member A
increases expression
EXP
Piperonyl Butoxide results in increased expression of FAM162A mRNA
CTD
PMID:15890375
NCBI chr11:64,680,978...64,709,865
Ensembl chr11:64,680,323...64,711,239
G
Fgf1
fibroblast growth factor 1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of FGF1 gene
CTD
PMID:23968726
NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
G
Fkbp4
FKBP prolyl isomerase 4
increases expression
EXP
Piperonyl Butoxide results in increased expression of FKBP4 mRNA
CTD
PMID:15890375
NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833
G
Flywch1
FLYWCH-type zinc finger 1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of FLYWCH1 gene
CTD
PMID:23968726
NCBI chr10:12,774,644...12,794,373
Ensembl chr10:12,774,653...12,794,267
G
Fmo1
flavin containing dimethylaniline monoxygenase 1
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of FMO1 mRNA
CTD
PMID:22484513
NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
G
Fn1
fibronectin 1
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of FN1 mRNA
CTD
PMID:15890375
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] results in increased expression of FOS mRNA
CTD
PMID:19690152
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
G
G6pd
glucose-6-phosphate dehydrogenase
multiple interactions
EXP
[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of G6PD protein
CTD
PMID:28903497
NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
G
Gaa
alpha glucosidase
increases expression
EXP
Piperonyl Butoxide results in increased expression of GAA mRNA
CTD
PMID:22484513
NCBI chr10:104,529,673...104,546,836
Ensembl chr10:104,529,747...104,546,836
G
Gadd45a
growth arrest and DNA-damage-inducible, alpha
increases expression multiple interactions
EXP
Piperonyl Butoxide results in increased expression of GADD45A mRNA Triterpenes promotes the reaction [Piperonyl Butoxide results in increased expression of GADD45A mRNA]
CTD
PMID:15890375 PMID:18544911
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
G
Galnt2
polypeptide N-acetylgalactosaminyltransferase 2
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of GALNT2 gene
CTD
PMID:23968726
NCBI chr19:52,213,226...52,324,816
Ensembl chr19:52,213,351...52,324,813
G
Gas6
growth arrest specific 6
increases expression
EXP
Piperonyl Butoxide results in increased expression of GAS6 mRNA
CTD
PMID:15890375
NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
G
Gclc
glutamate-cysteine ligase, catalytic subunit
increases expression
EXP
Piperonyl Butoxide results in increased expression of GCLC mRNA
CTD
PMID:15890375
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
G
Gdf15
growth differentiation factor 15
increases expression
EXP
Piperonyl Butoxide results in increased expression of GDF15 mRNA
CTD
PMID:15890375
NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
G
Ggt1
gamma-glutamyltransferase 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of GGT1 mRNA
CTD
PMID:22008526
NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
G
Ghr
growth hormone receptor
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of GHR mRNA
CTD
PMID:22484513
NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735
G
Gins4
GINS complex subunit 4
increases expression
EXP
Piperonyl Butoxide results in increased expression of GINS4 mRNA
CTD
PMID:22484513
NCBI chr16:68,787,572...68,799,938
Ensembl chr16:68,767,339...68,802,273
G
Gja1
gap junction protein, alpha 1
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of GJA1 mRNA
CTD
PMID:22484513
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
G
Gli1
GLI family zinc finger 1
decreases expression multiple interactions
ISO
Piperonyl Butoxide results in decreased expression of GLI1 mRNA Piperonyl Butoxide affects the reaction [PTCH1 protein affects the expression of GLI1 protein]; Piperonyl Butoxide inhibits the reaction [SMO protein results in increased expression of GLI1 protein]; SAG compound affects the reaction [Piperonyl Butoxide affects the reaction [PTCH1 protein affects the expression of GLI1 protein]] Piperonyl Butoxide inhibits the reaction [SHH protein results in increased expression of GLI1 mRNA]
CTD
PMID:31642701
NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251
G
Glrx
glutaredoxin
increases expression
EXP
Piperonyl Butoxide results in increased expression of GLRX mRNA
CTD
PMID:17498859
NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
G
Gls2
glutaminase 2
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of GLS2 mRNA
CTD
PMID:22484513
NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426
G
Glul
glutamate-ammonia ligase
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of GLUL mRNA
CTD
PMID:22484513
NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108
G
Gnmt
glycine N-methyltransferase
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of GNMT mRNA
CTD
PMID:22484513
NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434
G
Gpx2
glutathione peroxidase 2
multiple interactions increases expression affects expression
EXP
Piperonyl Butoxide affects the reaction [Phenobarbital affects the expression of GPX2 mRNA]; Triterpenes promotes the reaction [Piperonyl Butoxide results in increased expression of GPX2 mRNA] Piperonyl Butoxide affects the expression of GPX2 mRNA
CTD
PMID:17498859 PMID:18544911 PMID:22484513 PMID:24025784
NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
G
Grin2c
glutamate ionotropic receptor NMDA type subunit 2C
increases expression
EXP
Piperonyl Butoxide results in increased expression of GRIN2C mRNA
CTD
PMID:22008526 PMID:22484513
NCBI chr10:100,488,430...100,507,083
Ensembl chr10:100,488,431...100,506,427
G
Grpel1
GrpE-like 1, mitochondrial
increases expression
EXP
Piperonyl Butoxide results in increased expression of GRPEL1 mRNA
CTD
PMID:15890375
NCBI chr14:74,292,023...74,298,243
Ensembl chr14:74,292,023...74,298,200
G
Gspt1
G1 to S phase transition 1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of GSPT1 gene
CTD
PMID:23968726
NCBI chr10:4,362,528...4,397,215
Ensembl chr10:4,362,510...4,397,198
G
Gsr
glutathione-disulfide reductase
multiple interactions increases expression
EXP
Triterpenes promotes the reaction [Piperonyl Butoxide results in increased expression of GSR mRNA]
CTD
PMID:15890375 PMID:18544911 PMID:22484513
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
G
Gss
glutathione synthetase
increases expression
EXP
Piperonyl Butoxide results in increased expression of GSS mRNA
CTD
PMID:15890375 PMID:22484513
NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
G
Gsta2
glutathione S-transferase alpha 2
increases expression
EXP
Piperonyl Butoxide results in increased expression of GSTA2 mRNA
CTD
PMID:15890375 PMID:18544911
NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
G
Gsta4
glutathione S-transferase alpha 4
increases expression
EXP
Piperonyl Butoxide results in increased expression of GSTA4 mRNA
CTD
PMID:22484513
NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182
G
Gsta5
glutathione S-transferase alpha 5
increases expression multiple interactions
EXP
Piperonyl Butoxide results in increased expression of GSTA5 mRNA Triterpenes promotes the reaction [Piperonyl Butoxide results in increased expression of GSTA5 mRNA]
CTD
PMID:18544911
NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
G
Gstm1
glutathione S-transferase mu 1
increases expression multiple interactions
EXP
Piperonyl Butoxide results in increased expression of GSTM1 mRNA Triterpenes promotes the reaction [Piperonyl Butoxide results in increased expression of GSTM1 mRNA]
CTD
PMID:18544911
NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
G
Gstm4
glutathione S-transferase mu 4
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of GSTM4 gene
CTD
PMID:23968726
NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
G
Gstm5
glutathione S-transferase, mu 5
multiple interactions increases expression
EXP
Piperonyl Butoxide affects the reaction [Phenobarbital affects the expression of GSTM3 mRNA] Piperonyl Butoxide results in increased expression of GSTM3 mRNA
CTD
PMID:18544911 PMID:22484513 PMID:24025784
NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553
G
Gstp1
glutathione S-transferase pi 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of GSTP1 protein
CTD
PMID:18648771
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
G
H1f0
H1.0 linker histone
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of H1F0 mRNA
CTD
PMID:22484513
NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694
G
H2ax
H2A.X variant histone
increases expression
EXP
Piperonyl Butoxide results in increased expression of H2AX mRNA
CTD
PMID:15890375
NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
G
H2az1
H2A.Z variant histone 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of H2AZ1 mRNA
CTD
PMID:15890375
NCBI chr 2:226,355,668...226,357,984
Ensembl chr 2:226,355,708...226,358,485
G
Hal
histidine ammonia lyase
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of HAL mRNA
CTD
PMID:22484513
NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
G
Hdc
histidine decarboxylase
increases expression
EXP
Piperonyl Butoxide results in increased expression of HDC mRNA
CTD
PMID:15890375
NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
G
Hes6
hes family bHLH transcription factor 6
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of HES6 mRNA
CTD
PMID:22484513
NCBI chr 9:92,001,849...92,003,562
Ensembl chr 9:92,001,841...92,003,559
G
Hibch
3-hydroxyisobutyryl-CoA hydrolase
increases expression
EXP
Piperonyl Butoxide results in increased expression of HIBCH mRNA
CTD
PMID:22484513
NCBI chr 9:48,590,097...48,669,896
Ensembl chr 9:48,590,099...48,669,824
G
Hirip3
HIRA interacting protein 3
increases expression
EXP
Piperonyl Butoxide results in increased expression of HIRIP3 mRNA
CTD
PMID:22484513
NCBI chr 1:181,472,537...181,475,082
Ensembl chr 1:181,472,056...181,475,079
G
Hmgb2
high mobility group box 2
increases expression
EXP
Piperonyl Butoxide results in increased expression of HMGB2 mRNA
CTD
PMID:15890375
NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
G
Hmox1
heme oxygenase 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of HMOX1 mRNA
CTD
PMID:15890375
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Hpcal4
hippocalcin-like 4
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of HPCAL4 gene
CTD
PMID:23968726
NCBI chr 5:135,454,477...135,466,417
Ensembl chr 5:135,454,540...135,466,416
G
Hs3st3a1
heparan sulfate-glucosamine 3-sulfotransferase 3A1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of HS3ST3A1 gene
CTD
PMID:23968726
NCBI chr10:49,092,850...49,180,676
Ensembl chr10:49,094,026...49,180,676
G
Hscb
HscB mitochondrial iron-sulfur cluster co-chaperone
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of HSCB gene
CTD
PMID:23968726
NCBI chr12:45,821,527...45,831,902
Ensembl chr12:45,821,555...45,831,909
G
Hsd11b1
hydroxysteroid 11-beta dehydrogenase 1
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of HSD11B1 mRNA
CTD
PMID:22484513
NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
G
Hsf1
heat shock transcription factor 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of HSF1 mRNA
CTD
PMID:15890375
NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
G
Hsp90aa1
heat shock protein 90 alpha family class A member 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of HSP90AA1 mRNA
CTD
PMID:22484513
NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
G
Hspa9
heat shock protein family A (Hsp70) member 9
increases expression
EXP
Piperonyl Butoxide results in increased expression of HSPA9 mRNA
CTD
PMID:15890375
NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
G
Hspb1
heat shock protein family B (small) member 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of HSPB1 mRNA
CTD
PMID:15890375 PMID:22484513
NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
G
Hspe1
heat shock protein family E (Hsp10) member 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of HSPE1 mRNA
CTD
PMID:15890375
NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
G
Hsph1
heat shock protein family H (Hsp110) member 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of HSPH1 mRNA
CTD
PMID:15890375 PMID:22484513
NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
G
Htatip2
HIV-1 Tat interactive protein 2
increases expression
EXP
Piperonyl Butoxide results in increased expression of HTATIP2 mRNA
CTD
PMID:22484513
NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
G
Htr6
5-hydroxytryptamine receptor 6
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of HTR6 gene
CTD
PMID:23968726
NCBI chr 5:151,295,269...151,312,853
Ensembl chr 5:151,296,662...151,311,912
G
Hyal3
hyaluronidase 3
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of HYAL3 mRNA
CTD
PMID:22484513
NCBI chr 8:108,254,385...108,260,020
Ensembl chr 8:108,250,667...108,260,647
G
Icam1
intercellular adhesion molecule 1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of ICAM1 gene
CTD
PMID:23968726
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
G
Ide
insulin degrading enzyme
increases expression
EXP
Piperonyl Butoxide results in increased expression of IDE mRNA
CTD
PMID:15890375
NCBI chr 1:235,002,984...235,102,448
Ensembl chr 1:234,995,351...235,102,440
G
Ifi27l2a
interferon, alpha-inducible protein 27 like 2A
increases expression
EXP
Piperonyl Butoxide results in increased expression of ISG12(B) mRNA
CTD
PMID:22484513
NCBI chr 6:122,598,872...122,600,358
Ensembl chr 6:122,598,872...122,600,360
G
Ifng
interferon gamma
multiple interactions increases expression
ISO
[bioallethrin co-treated with Piperonyl Butoxide] results in increased expression of IFNG protein Piperonyl Butoxide results in increased expression of IFNG protein
CTD
PMID:10414782 PMID:22842586
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
G
Ifrd1
interferon-related developmental regulator 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of IFRD1 mRNA
CTD
PMID:22484513
NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
G
Igfbp1
insulin-like growth factor binding protein 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of IGFBP1 mRNA
CTD
PMID:15890375
NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
G
Igfbp3
insulin-like growth factor binding protein 3
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of IGFBP3 mRNA
CTD
PMID:15890375
NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
G
Igsf9
immunoglobulin superfamily, member 9
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of IGSF9 gene
CTD
PMID:23968726
NCBI chr13:84,948,643...84,965,616
Ensembl chr13:84,948,619...84,965,607
G
Ihh
Indian hedgehog signaling molecule
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of IHH gene
CTD
PMID:23968726
NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
G
Il13
interleukin 13
increases expression multiple interactions
ISO
Piperonyl Butoxide results in increased expression of IL13 mRNA [Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of IL13 gene
CTD
PMID:22842586 PMID:23968726
NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
G
Il17a
interleukin 17A
increases expression
ISO
Piperonyl Butoxide results in increased expression of IL17A mRNA
CTD
PMID:22842586
NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
G
Il1b
interleukin 1 beta
increases expression
ISO
Piperonyl Butoxide results in increased expression of IL1B protein
CTD
PMID:36941454
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Il4
interleukin 4
multiple interactions increases expression
ISO
[bioallethrin co-treated with Piperonyl Butoxide] results in increased expression of IL4 protein Piperonyl Butoxide results in increased expression of IL4 mRNA; Piperonyl Butoxide results in increased expression of IL4 protein
CTD
PMID:10414782 PMID:22842586
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
G
Il6
interleukin 6
increases expression
ISO
Piperonyl Butoxide results in increased expression of IL6 protein
CTD
PMID:22842586
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Incenp
inner centromere protein
increases expression
EXP
Piperonyl Butoxide results in increased expression of INCENP protein
CTD
PMID:23411599
NCBI chr 1:206,520,655...206,550,575
Ensembl chr 1:206,523,380...206,553,265
G
Itgax
integrin subunit alpha X
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of ITGAX gene
CTD
PMID:23968726
NCBI chr 1:182,709,653...182,740,709
Ensembl chr 1:182,719,609...182,740,698
G
Jun
Jun proto-oncogene, AP-1 transcription factor subunit
multiple interactions increases phosphorylation
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] results in increased expression of JUN mRNA Piperonyl Butoxide results in increased phosphorylation of JUN protein
CTD
PMID:18228000 PMID:19690152
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
G
Kcng4
potassium voltage-gated channel modifier subfamily G member 4
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of KCNG4 gene
CTD
PMID:23968726
NCBI chr19:47,677,307...47,689,410
Ensembl chr19:47,677,327...47,689,268
G
Kcnj9
potassium inwardly-rectifying channel, subfamily J, member 9
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of KCNJ9 gene
CTD
PMID:23968726
NCBI chr13:84,780,826...84,787,928
Ensembl chr13:84,779,741...84,787,928
G
Kcnq1
potassium voltage-gated channel subfamily Q member 1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of KCNQ1 gene
CTD
PMID:23968726
NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
G
Kif26b
kinesin family member 26B
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of KIF26B gene
CTD
PMID:23968726
NCBI chr13:90,282,821...90,689,058
Ensembl chr13:90,283,404...90,682,811
G
Klf6
KLF transcription factor 6
increases expression
EXP
Piperonyl Butoxide results in increased expression of KLF6 mRNA
CTD
PMID:23411599
NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
G
Kras
KRAS proto-oncogene, GTPase
increases mutagenesis
ISO
Piperonyl Butoxide results in increased mutagenesis of KRAS gene
CTD
PMID:7565889
NCBI chr 4:178,185,418...178,218,484
G
Krt18
keratin 18
multiple interactions
ISO
[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of KRT18 protein
CTD
PMID:20101389
NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
G
Krt73
keratin 73
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of KRT73 gene
CTD
PMID:23968726
NCBI chr 7:132,927,812...132,936,323
Ensembl chr 7:132,928,256...132,936,280
G
Krt8
keratin 8
multiple interactions
ISO
[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of KRT8 protein
CTD
PMID:20101389
NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
G
Lcmt2
leucine carboxyl methyltransferase 2
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of LCMT2 mRNA
CTD
PMID:22484513
NCBI chr 3:108,099,960...108,102,084
Ensembl chr 3:108,099,961...108,102,084
G
Lgals3
galectin 3
increases expression
EXP
Piperonyl Butoxide results in increased expression of LGALS3 mRNA
CTD
PMID:15890375
NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
G
Lifr
LIF receptor subunit alpha
decreases expression
EXP
[Piperonyl Butoxide results in decreased expression of ESR1 mRNA] which results in decreased expression of LIFR mRNA; Piperonyl Butoxide results in decreased expression of LIFR mRNA
CTD
PMID:22467018
NCBI chr 2:56,224,393...56,292,988
Ensembl chr 2:56,250,120...56,286,699
G
Lrrc42
leucine rich repeat containing 42
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of LRRC42 gene
CTD
PMID:23968726
NCBI chr 5:122,014,678...122,035,792
Ensembl chr 5:122,014,678...122,035,829
G
Lrrc52
leucine rich repeat containing 52
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of LRRC52 gene
CTD
PMID:23968726
NCBI chr13:79,597,244...79,620,640
Ensembl chr13:79,597,245...79,620,640
G
Lsp1
lymphocyte-specific protein 1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of LSP1 gene
CTD
PMID:23968726
NCBI chr 1:197,614,677...197,648,414
Ensembl chr 1:197,614,687...197,648,416
G
Lta4h
leukotriene A4 hydrolase
multiple interactions
ISO
Piperonyl Butoxide inhibits the reaction [LTA4H protein results in increased chemical synthesis of Leukotriene B4]; Piperonyl Butoxide inhibits the reaction [LTA4H protein results in increased hydrolysis of Leukotriene A4]
CTD
PMID:2827578
NCBI chr 7:27,969,796...28,001,600
Ensembl chr 7:27,969,789...28,001,600
G
Ltbp4
latent transforming growth factor beta binding protein 4
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of LTBP4 gene
CTD
PMID:23968726
NCBI chr 1:82,600,136...82,634,346
Ensembl chr 1:82,600,136...82,632,178
G
Macrod1
mono-ADP ribosylhydrolase 1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of MACROD1 gene
CTD
PMID:23968726
NCBI chr 1:204,246,238...204,387,027
Ensembl chr 1:204,246,166...204,389,716
G
Mad2l1
mitotic arrest deficient 2 like 1
increases expression
ISO
Piperonyl Butoxide results in increased expression of MAD2L1 mRNA
CTD
PMID:30572783
NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470
G
Maged2
MAGE family member D2
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of MAGED2 gene
CTD
PMID:23968726
NCBI chr X:19,733,593...19,741,769
Ensembl chr X:19,733,597...19,740,477
G
Map1s
microtubule-associated protein 1S
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of MAP1S gene
CTD
PMID:23968726
NCBI chr16:18,516,759...18,527,777
Ensembl chr16:18,517,574...18,527,988
G
Map2k6
mitogen-activated protein kinase kinase 6
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of MAP2K6 mRNA
CTD
PMID:22484513
NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
G
Marveld1
MARVEL domain containing 1
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of MARVELD1 mRNA
CTD
PMID:22484513
NCBI chr 1:240,954,050...240,958,101
Ensembl chr 1:240,954,452...240,958,384
G
Mat1a
methionine adenosyltransferase 1A
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of MAT1A mRNA
CTD
PMID:22484513
NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274
G
Mcm5
minichromosome maintenance complex component 5
increases expression
EXP
Piperonyl Butoxide results in increased expression of MCM5 mRNA
CTD
PMID:22484513
NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
G
Mcm6
minichromosome maintenance complex component 6
increases expression
EXP ISO
Piperonyl Butoxide results in increased expression of MCM6 mRNA
CTD
PMID:15890375 PMID:22484513 PMID:30572783
NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
G
Mdm2
MDM2 proto-oncogene
increases expression
EXP
Piperonyl Butoxide results in increased expression of MDM2 mRNA
CTD
PMID:15890375 PMID:22484513
NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
G
Me1
malic enzyme 1
multiple interactions increases expression
EXP
Triterpenes promotes the reaction [Piperonyl Butoxide results in increased expression of ME1 mRNA]
CTD
PMID:18544911 PMID:22484513
NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
G
Mgmt
O-6-methylguanine-DNA methyltransferase
increases expression
EXP
Piperonyl Butoxide results in increased expression of MGMT mRNA
CTD
PMID:15890375
NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
G
Mgst2
microsomal glutathione S-transferase 2
increases expression
EXP
Piperonyl Butoxide results in increased expression of MGST2 mRNA
CTD
PMID:22484513
NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828
G
Mlc1
modulator of VRAC current 1
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of MLC1 mRNA
CTD
PMID:22484513
NCBI chr 7:120,046,705...120,067,049
Ensembl chr 7:120,046,705...120,067,049
G
Mlec
malectin
increases expression
EXP
Piperonyl Butoxide results in increased expression of MLEC mRNA
CTD
PMID:22484513
NCBI chr12:41,458,234...41,468,710
Ensembl chr12:41,458,231...41,468,708
G
Mrpl55
mitochondrial ribosomal protein L55
increases expression
EXP
Piperonyl Butoxide results in increased expression of MRPL55 mRNA
CTD
PMID:22484513
NCBI chr10:43,988,676...43,991,841
Ensembl chr10:43,988,683...43,991,841
G
Mt1
metallothionein 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of MT1A mRNA
CTD
PMID:15890375
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049
G
Mt2A
metallothionein 2A
increases expression
EXP
Piperonyl Butoxide results in increased expression of MT2A mRNA
CTD
PMID:15890375
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
G
Mybpc3
myosin binding protein C3
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of MYBPC3 gene
CTD
PMID:23968726
NCBI chr 3:77,095,165...77,113,406
Ensembl chr 3:77,095,252...77,113,405
G
Myc
MYC proto-oncogene, bHLH transcription factor
multiple interactions increases expression
ISO EXP
[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of MYC mRNA; [Piperonyl Butoxide co-treated with Diethylnitrosamine] results in increased expression of MYC mRNA Piperonyl Butoxide results in increased expression of MYC mRNA
CTD
PMID:15890375 PMID:19690152 PMID:20101389
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
G
Naa11
N(alpha)-acetyltransferase 11, NatA catalytic subunit
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of NAA11 gene
CTD
PMID:23968726
NCBI chr14:12,183,651...12,193,687
Ensembl chr14:12,183,651...12,193,686
G
Nap1l1
nucleosome assembly protein 1-like 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of NAP1L1 mRNA
CTD
PMID:15890375 PMID:22484513
NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593
G
Ncapd3
non-SMC condensin II complex, subunit D3
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of NCAPD3 gene
CTD
PMID:23968726
NCBI chr 8:25,437,067...25,506,375
Ensembl chr 8:25,437,123...25,506,373
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Nfe2l2
NFE2 like bZIP transcription factor 2
increases expression multiple interactions increases activity
ISO
Piperonyl Butoxide results in increased expression of NFE2L2 mRNA [Piperonyl Butoxide co-treated with Diethylnitrosamine] results in increased expression of NFE2L2 mRNA Piperonyl Butoxide results in increased activity of NFE2L2 protein
CTD
PMID:19690152 PMID:30203046
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nfia
nuclear factor I/A
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of NFIA mRNA
CTD
PMID:22484513
NCBI chr 5:112,436,655...112,781,878
Ensembl chr 5:112,436,644...112,775,885
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Nherf1
NHERF family PDZ scaffold protein 1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of NHERF1 gene
CTD
PMID:23968726
NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598
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Nhlh2
nescient helix loop helix 2
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of NHLH2 gene
CTD
PMID:23968726
NCBI chr 2:189,444,287...189,449,625
Ensembl chr 2:189,442,711...189,449,625
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Nhp2
NHP2 ribonucleoprotein
increases expression
EXP
Piperonyl Butoxide results in increased expression of NOLA2 mRNA
CTD
PMID:22484513
NCBI chr10:35,877,057...35,880,399
Ensembl chr10:35,877,054...35,882,545
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Nisch
nischarin
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of NISCH gene
CTD
PMID:23968726
NCBI chr16:6,364,370...6,400,675
Ensembl chr16:6,364,374...6,400,668
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Nmnat2
nicotinamide nucleotide adenylyltransferase 2
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of NMNAT2 gene
CTD
PMID:23968726
NCBI chr13:65,105,950...65,277,350
Ensembl chr13:65,105,950...65,278,484
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Nod1
nucleotide-binding oligomerization domain containing 1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of NOD1 gene
CTD
PMID:23968726
NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404
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Npm1
nucleophosmin 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of NPM1 mRNA
CTD
PMID:15890375
NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
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Nqo1
NAD(P)H quinone dehydrogenase 1
multiple interactions increases expression affects expression
ISO EXP
[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of NQO1 mRNA; [Piperonyl Butoxide co-treated with Diethylnitrosamine] results in increased expression of NQO1 mRNA Triterpenes promotes the reaction [Piperonyl Butoxide results in increased expression of NQO1 mRNA] Piperonyl Butoxide affects the expression of NQO1 mRNA
CTD
PMID:15890375 PMID:17498859 PMID:18544911 PMID:19690152 PMID:20101389 PMID:22484513 PMID:22972318 PMID:24025784 More...
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Nr1h2
nuclear receptor subfamily 1, group H, member 2
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of NR1H2 gene
CTD
PMID:23968726
NCBI chr 1:95,041,967...95,047,358
Ensembl chr 1:95,041,967...95,047,377
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Nr1i2
nuclear receptor subfamily 1, group I, member 2
multiple interactions affects response to substance
ISO
[NR1I2 gene mutant form affects the susceptibility to Piperonyl Butoxide] which results in increased expression of ACOX1 mRNA
CTD
PMID:32320717
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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Nr1i3
nuclear receptor subfamily 1, group I, member 3
affects response to substance increases activity multiple interactions
ISO
NR1I3 gene mutant form affects the susceptibility to Piperonyl Butoxide; NR1I3 protein affects the susceptibility to Piperonyl Butoxide Piperonyl Butoxide results in increased activity of NR1I3 protein [NR1I3 gene mutant form affects the susceptibility to Piperonyl Butoxide] which results in increased expression of ACOX1 mRNA
CTD
PMID:26558459 PMID:30203046 PMID:32320717
NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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Nrbp2
nuclear receptor binding protein 2
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of NRBP2 mRNA
CTD
PMID:22484513
NCBI chr 7:107,798,642...107,805,225
Ensembl chr 7:107,799,497...107,805,230
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Nrep
neuronal regeneration related protein
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of NREP mRNA
CTD
PMID:22484513
NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591
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Nrg1
neuregulin 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of NRG1 mRNA
CTD
PMID:15890375
NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
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Nupr1
nuclear protein 1, transcriptional regulator
increases expression
EXP
Piperonyl Butoxide results in increased expression of NUPR1 mRNA
CTD
PMID:15890375
NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281
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Oaf
out at first homolog
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of OAF mRNA
CTD
PMID:22484513
NCBI chr 8:43,594,362...43,612,334
Ensembl chr 8:43,594,363...43,612,334
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Oat
ornithine aminotransferase
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of OAT mRNA
CTD
PMID:22484513
NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
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Obp3
alpha-2u globulin PGCL4
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of OBP3 mRNA
CTD
PMID:15890375
NCBI chr 5:74,842,316...74,845,858
Ensembl chr 5:74,842,316...74,845,757
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Odc1
ornithine decarboxylase 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of ODC1 mRNA
CTD
PMID:15890375
NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
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Ogg1
8-oxoguanine DNA glycosylase
multiple interactions
ISO
[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in decreased expression of OGG1 mRNA
CTD
PMID:20101389
NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
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Or5au1
olfactory receptor family 5 subfamily AU member 1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of OR5AU1 gene
CTD
PMID:23968726
NCBI chr15:24,736,872...24,742,314
Ensembl chr15:24,737,497...24,743,632
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Orc6
origin recognition complex, subunit 6
increases expression
EXP
Piperonyl Butoxide results in increased expression of ORC6 mRNA
CTD
PMID:22484513
NCBI chr19:21,757,867...21,765,638
Ensembl chr19:21,757,866...21,765,662
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Orm1
orosomucoid 1
increases expression
ISO
Piperonyl Butoxide results in increased expression of ORM1 protein
CTD
PMID:20025956
NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154
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Panx2
pannexin 2
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of PANX2 gene
CTD
PMID:23968726
NCBI chr 7:120,139,259...120,153,056
Ensembl chr 7:120,139,294...120,152,361
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Paqr6
progestin and adipoQ receptor family member 6
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of PAQR6 gene
CTD
PMID:23968726
NCBI chr 2:173,832,241...173,838,443
Ensembl chr 2:173,833,880...173,838,456
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Pask
PAS domain containing serine/threonine kinase
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of PASK gene
CTD
PMID:23968726
NCBI chr 9:93,844,275...93,886,036
Ensembl chr 9:93,844,278...93,885,111
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Pclaf
PCNA clamp associated factor
increases expression
EXP
Piperonyl Butoxide results in increased expression of PCLAF mRNA
CTD
PMID:22484513
NCBI chr 8:66,420,606...66,432,994
Ensembl chr 8:66,420,587...66,432,994 Ensembl chr 8:66,420,587...66,432,994
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Pcna
proliferating cell nuclear antigen
multiple interactions increases expression
ISO EXP
[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of PCNA protein Piperonyl Butoxide results in increased expression of PCNA mRNA
CTD
PMID:15890375 PMID:20101389 PMID:22484513
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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Pcnt
pericentrin
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of PCNT gene
CTD
PMID:23968726
NCBI chr20:12,190,597...12,278,723
Ensembl chr20:12,191,648...12,278,710
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Pdcd4
programmed cell death 4
decreases expression increases expression
ISO
Piperonyl Butoxide results in decreased expression of PDCD4 mRNA Piperonyl Butoxide results in increased expression of PDCD4 mRNA
CTD
PMID:21873647
NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275
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Pex11a
peroxisomal biogenesis factor 11 alpha
increases expression
EXP
Piperonyl Butoxide results in increased expression of PEX11A mRNA
CTD
PMID:22484513
NCBI chr 1:133,680,091...133,687,172
Ensembl chr 1:133,680,091...133,687,172
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Phgdh
phosphoglycerate dehydrogenase
increases expression
EXP
Piperonyl Butoxide results in increased expression of PHGDH mRNA
CTD
PMID:15890375
NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944
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Pklr
pyruvate kinase L/R
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of PKLR mRNA
CTD
PMID:22484513
NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
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Pla2g12a
phospholipase A2, group XIIA
increases expression
EXP
Piperonyl Butoxide results in increased expression of PLA2G12A mRNA
CTD
PMID:22484513
NCBI chr 2:218,436,497...218,452,742
Ensembl chr 2:218,436,513...218,452,740
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Pla2g5
phospholipase A2, group V
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of PLA2G5 gene
CTD
PMID:23968726
NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658
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Plaat3
phospholipase A and acyltransferase 3
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of PLAAT3 mRNA
CTD
PMID:22484513
NCBI chr 1:204,782,608...204,816,397
Ensembl chr 1:204,782,729...204,817,667
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Plec
plectin
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of PLEC gene
CTD
PMID:23968726
NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467
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Plekha5
pleckstrin homology domain containing A5
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of PLEKHA5 mRNA
CTD
PMID:22484513
NCBI chr 4:173,333,891...173,503,546
Ensembl chr 4:173,334,055...173,503,546
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Plekho1
pleckstrin homology domain containing O1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of PLEKHO1 gene
CTD
PMID:23968726
NCBI chr 2:183,544,487...183,552,928
Ensembl chr 2:183,544,499...183,552,785
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Plod3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of PLOD3 gene
CTD
PMID:23968726
NCBI chr12:19,676,384...19,686,945
Ensembl chr12:19,676,386...19,686,960
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Polrmt
RNA polymerase mitochondrial
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of POLRMT gene
CTD
PMID:23968726
NCBI chr 7:9,959,532...9,969,791
Ensembl chr 7:9,959,576...9,969,791
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Por
cytochrome p450 oxidoreductase
multiple interactions increases expression
ISO EXP
[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of POR mRNA; [Piperonyl Butoxide co-treated with Diethylnitrosamine] results in increased expression of POR mRNA Piperonyl Butoxide results in increased expression of POR mRNA
CTD
PMID:17014948 PMID:19690152 PMID:20101389 PMID:22484513
NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
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Pou2f2
POU class 2 homeobox 2
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of POU2F2 gene
CTD
PMID:23968726
NCBI chr 1:80,682,330...80,769,756
Ensembl chr 1:80,685,741...80,724,261
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Pou5f1
POU class 5 homeobox 1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of POU5F1 gene
CTD
PMID:23968726
NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
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Prodh
proline dehydrogenase
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of PRODH mRNA
CTD
PMID:22484513
NCBI chr11:82,910,043...82,927,305
Ensembl chr11:82,910,137...82,927,305
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Prpf8
pre-mRNA processing factor 8
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of PRPF8 gene
CTD
PMID:23968726
NCBI chr10:60,331,494...60,354,606
Ensembl chr10:60,331,494...60,354,606
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Prrc2b
proline-rich coiled-coil 2B
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of PRRC2B gene
CTD
PMID:23968726
NCBI chr 3:15,433,357...15,519,105
Ensembl chr 3:15,465,294...15,519,104
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Psma1
proteasome 20S subunit alpha 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of PSMA1 mRNA
CTD
PMID:15890375
NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472
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Psma2
proteasome 20S subunit alpha 2
increases expression
EXP
Piperonyl Butoxide results in increased expression of PSMA2 mRNA
CTD
PMID:15890375 PMID:22484513
NCBI chr17:50,554,536...50,564,923
Ensembl chr17:50,551,924...50,564,938
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Psma4
proteasome 20S subunit alpha 4
increases expression
EXP
Piperonyl Butoxide results in increased expression of PSMA4 mRNA
CTD
PMID:15890375 PMID:22484513
NCBI chr 8:55,340,431...55,347,893
Ensembl chr 8:55,340,386...55,347,890
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Psma5
proteasome 20S subunit alpha 5
increases expression
EXP
Piperonyl Butoxide results in increased expression of PSMA5 mRNA
CTD
PMID:15890375 PMID:22484513
NCBI chr 2:195,896,369...195,919,733
Ensembl chr 2:195,896,365...195,919,731
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Psma7
proteasome 20S subunit alpha 7
increases expression
EXP
Piperonyl Butoxide results in increased expression of PSMA7 mRNA
CTD
PMID:15890375 PMID:22484513
NCBI chr 3:167,137,279...167,143,626
Ensembl chr 3:167,137,263...167,143,672
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Psmb1
proteasome 20S subunit beta 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of PSMB1 mRNA
CTD
PMID:15890375 PMID:22484513
NCBI chr 1:56,442,432...56,463,544
Ensembl chr 1:56,420,618...56,463,560
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Psmb3
proteasome 20S subunit beta 3
increases expression
EXP
Piperonyl Butoxide results in increased expression of PSMB3 mRNA
CTD
PMID:15890375 PMID:22484513
NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521
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Psmb4
proteasome 20S subunit beta 4
increases expression
EXP
Piperonyl Butoxide results in increased expression of PSMB4 mRNA
CTD
PMID:15890375 PMID:22484513
NCBI chr 2:182,442,757...182,445,532
Ensembl chr 2:182,442,756...182,445,746
G
Psmb5
proteasome 20S subunit beta 5
increases expression
EXP
Piperonyl Butoxide results in increased expression of PSMB5 mRNA
CTD
PMID:15890375 PMID:22484513
NCBI chr15:28,072,772...28,077,367
Ensembl chr15:28,072,781...28,077,440
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Psmb6
proteasome 20S subunit beta 6
increases expression
EXP
Piperonyl Butoxide results in increased expression of PSMB6 mRNA
CTD
PMID:22484513
NCBI chr10:55,239,256...55,241,586
Ensembl chr10:55,239,241...55,241,586
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Psmb7
proteasome 20S subunit beta 7
increases expression
EXP
Piperonyl Butoxide results in increased expression of PSMB7 mRNA
CTD
PMID:22484513
NCBI chr 3:22,357,777...22,417,748
Ensembl chr 3:22,354,698...22,417,937
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Psmc1
proteasome 26S subunit, ATPase 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of PSMC1 mRNA
CTD
PMID:15890375
NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123
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Psmc2
proteasome 26S subunit, ATPase 2
increases expression
EXP
Piperonyl Butoxide results in increased expression of PSMC2 mRNA
CTD
PMID:15890375 PMID:22484513
NCBI chr 4:13,255,850...13,270,160
Ensembl chr 4:13,255,856...13,270,185
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Psmc3
proteasome 26S subunit, ATPase 3
increases expression
EXP
Piperonyl Butoxide results in increased expression of PSMC3 mRNA
CTD
PMID:22484513
NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358
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Psmc4
proteasome 26S subunit, ATPase 4
increases expression
EXP
Piperonyl Butoxide results in increased expression of PSMC4 mRNA
CTD
PMID:15890375 PMID:22484513
NCBI chr 1:83,349,127...83,357,497
Ensembl chr 1:83,348,592...83,357,494
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Psmc5
proteasome 26S subunit, ATPase 5
increases expression
EXP
Piperonyl Butoxide results in increased expression of PSMC5 mRNA
CTD
PMID:15890375 PMID:22484513
NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135
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Psmd1
proteasome 26S subunit, non-ATPase 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of PSMD1 mRNA
CTD
PMID:15890375 PMID:22484513
NCBI chr 9:86,709,714...86,785,213
Ensembl chr 9:86,709,947...86,785,211
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Psmd13
proteasome 26S subunit, non-ATPase 13
increases expression
EXP
Piperonyl Butoxide results in increased expression of PSMD13 mRNA
CTD
PMID:22484513
NCBI chr 1:195,964,617...195,976,895
Ensembl chr 1:195,964,138...195,976,905
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Psmd2
proteasome 26S subunit ubiquitin receptor, non-ATPase 2
increases expression
EXP
Piperonyl Butoxide results in increased expression of PSMD2 mRNA
CTD
PMID:22484513
NCBI chr11:80,248,364...80,258,991
Ensembl chr11:80,248,364...80,259,043
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Psmd4
proteasome 26S subunit ubiquitin receptor, non-ATPase 4
increases expression
EXP
Piperonyl Butoxide results in increased expression of PSMD4 mRNA
CTD
PMID:22484513
NCBI chr 2:182,598,934...182,608,250
Ensembl chr 2:182,598,934...182,608,194
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Psmd8
proteasome 26S subunit, non-ATPase 8
increases expression
EXP
Piperonyl Butoxide results in increased expression of PSMD8 mRNA
CTD
PMID:22484513
NCBI chr 1:84,474,377...84,481,209
Ensembl chr 1:84,474,378...84,481,209
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Ptch1
patched 1
multiple interactions
ISO
Piperonyl Butoxide affects the reaction [PTCH1 protein affects the expression of GLI1 protein]; SAG compound affects the reaction [Piperonyl Butoxide affects the reaction [PTCH1 protein affects the expression of GLI1 protein]]
CTD
PMID:31642701
NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333
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Ptp4a1
protein tyrosine phosphatase 4A1
increases expression
EXP
Piperonyl Butoxide results in increased expression of PTP4A1 mRNA
CTD
PMID:15890375
NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:33,214,208...33,221,964
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Ptpn21
protein tyrosine phosphatase, non-receptor type 21
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of PTPN21 gene
CTD
PMID:23968726
NCBI chr 6:117,933,066...117,998,095
Ensembl chr 6:117,933,066...117,998,095
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Ptprs
protein tyrosine phosphatase, receptor type, S
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of PTPRS mRNA
CTD
PMID:22484513
NCBI chr 9:1,245,408...1,307,015
Ensembl chr 9:1,245,410...1,306,947
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Pttg1
PTTG1 regulator of sister chromatid separation, securin
increases expression
EXP
Piperonyl Butoxide results in increased expression of PTTG1 mRNA
CTD
PMID:15890375
NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
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Racgap1
Rac GTPase-activating protein 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of RACGAP1 mRNA
CTD
PMID:22484513
NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
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Rad50
RAD50 double strand break repair protein
increases expression multiple interactions
EXP
Piperonyl Butoxide results in increased expression of RAD50 mRNA Triterpenes promotes the reaction [Piperonyl Butoxide results in increased expression of RAD50 mRNA]
CTD
PMID:18544911
NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396
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Ran
RAN, member RAS oncogene family
increases expression
EXP
Piperonyl Butoxide results in increased expression of RAN mRNA
CTD
PMID:22484513
NCBI chr12:27,674,049...27,678,598
Ensembl chr12:27,674,050...27,678,276
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Rangap1
RAN GTPase activating protein 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of RANGAP1 mRNA
CTD
PMID:22484513
NCBI chr 7:113,224,695...113,250,441
Ensembl chr 7:113,224,703...113,250,438
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Rasal3
RAS protein activator like 3
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of RASAL3 gene
CTD
PMID:23968726
NCBI chr 7:11,396,554...11,411,347
Ensembl chr 7:11,396,090...11,411,465
G
Rb1
RB transcriptional corepressor 1
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of RB1 mRNA
CTD
PMID:15890375
NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
G
Rbmxl1
Rbmx like 1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of RBMY1A1 gene
CTD
PMID:23968726
NCBI chr19:29,407,902...29,411,519
Ensembl chr19:29,407,912...29,412,859
G
Reep6
receptor accessory protein 6
increases expression
EXP
Piperonyl Butoxide results in increased expression of REEP6 mRNA
CTD
PMID:22484513
NCBI chr 7:9,373,927...9,380,845
Ensembl chr 7:9,373,927...9,380,597
G
Rfc2
replication factor C subunit 2
increases expression
EXP
Piperonyl Butoxide results in increased expression of RFC2 mRNA
CTD
PMID:22484513
NCBI chr12:22,120,449...22,133,576
Ensembl chr12:22,120,010...22,133,557
G
Rgn
regucalcin
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of RGN mRNA
CTD
PMID:22484513
NCBI chr X:1,619,030...1,634,456
Ensembl chr X:1,619,032...1,634,450
G
Rheb
Ras homolog, mTORC1 binding
increases expression
EXP
Piperonyl Butoxide results in increased expression of RHEB mRNA
CTD
PMID:15890375
NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160
G
Rhox9
reproductive homeobox 9
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of RHOX9 gene
CTD
PMID:23968726
NCBI chr X:116,641,863...116,644,714
Ensembl chr X:116,641,863...116,644,714
G
Rin3
Ras and Rab interactor 3
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of RIN3 gene
CTD
PMID:23968726
NCBI chr 6:121,431,776...121,540,956
Ensembl chr 6:121,431,339...121,540,957
G
Rnase4
ribonuclease A family member 4
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of RNASE4 mRNA
CTD
PMID:22484513
NCBI chr15:24,312,765...24,330,112
Ensembl chr15:24,312,464...24,330,117
G
Rnf123
ring finger protein 123
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of RNF123 gene
CTD
PMID:23968726
NCBI chr 8:108,740,176...108,768,177
Ensembl chr 8:108,739,620...108,767,675
G
Rora
RAR-related orphan receptor A
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of RORA mRNA
CTD
PMID:22484513
NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931
G
Rpl10
ribosomal protein L10
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of RPL10 mRNA
CTD
PMID:15890375
NCBI chr X:152,054,562...152,056,769
Ensembl chr X:152,054,452...152,056,761
G
Rpl10a
ribosomal protein L10A
increases expression
EXP
Piperonyl Butoxide results in increased expression of RPL10A mRNA
CTD
PMID:15890375
NCBI chr20:6,388,800...6,391,358
Ensembl chr20:6,385,823...6,391,357
G
Rpl13
ribosomal protein L13
increases expression
EXP
Piperonyl Butoxide results in increased expression of RPL13 mRNA
CTD
PMID:15890375
NCBI chr19:51,153,990...51,156,541
Ensembl chr19:51,153,924...51,163,014
G
Rpl15
ribosomal protein L15
increases expression
EXP
Piperonyl Butoxide results in increased expression of RPL15 mRNA
CTD
PMID:15890375
NCBI chr15:7,503,883...7,507,166
Ensembl chr15:7,503,883...7,507,165
G
Rpl17
ribosomal protein L17
increases expression
EXP
Piperonyl Butoxide results in increased expression of RPL17 mRNA
CTD
PMID:15890375
NCBI chr18:68,581,141...68,584,253
Ensembl chr18:68,581,098...68,584,253
G
Rpl23
ribosomal protein L23
increases expression
EXP
Piperonyl Butoxide results in increased expression of RPL23 mRNA
CTD
PMID:15890375
NCBI chr10:82,771,878...82,775,840
Ensembl chr10:82,771,538...82,775,870
G
Rpl6
ribosomal protein L6
increases expression
EXP
Piperonyl Butoxide results in increased expression of RPL6 mRNA
CTD
PMID:15890375
NCBI chr12:35,347,493...35,352,011
Ensembl chr12:35,347,497...35,351,921
G
Rpl7a
ribosomal protein L7A
increases expression
EXP
Piperonyl Butoxide results in increased expression of RPL7A mRNA
CTD
PMID:15890375
NCBI chr 3:10,239,026...10,241,703
Ensembl chr 3:10,239,001...10,241,716
G
Rpl8
ribosomal protein L8
increases expression
EXP
Piperonyl Butoxide results in increased expression of RPL8 mRNA
CTD
PMID:15890375
NCBI chr 7:108,626,194...108,628,485
Ensembl chr 7:108,622,324...108,628,482 Ensembl chr 3:108,622,324...108,628,482
G
Rps15a
ribosomal protein S15a
increases expression
EXP
Piperonyl Butoxide results in increased expression of RPS15A mRNA
CTD
PMID:15890375
NCBI chr 1:172,420,151...172,427,021
Ensembl chr 1:172,419,761...172,426,995
G
Rps19
ribosomal protein S19
increases expression
EXP
Piperonyl Butoxide results in increased expression of RPS19 mRNA
CTD
PMID:15890375
NCBI chr 1:80,480,718...80,486,511
Ensembl chr 1:80,480,951...80,486,508
G
Rps24
ribosomal protein S24
increases expression
EXP
Piperonyl Butoxide results in increased expression of RPS24 mRNA
CTD
PMID:15890375
NCBI chr16:89,538...94,267
Ensembl chr16:89,604...94,279
G
Rps27l
ribosomal protein S27-like
increases expression
EXP
Piperonyl Butoxide results in increased expression of RPS27L mRNA
CTD
PMID:15890375
NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418
G
Rps3
ribosomal protein S3
increases expression
EXP
Piperonyl Butoxide results in increased expression of RPS3 mRNA
CTD
PMID:15890375
NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680
G
Rps4x
ribosomal protein S4, X-linked
increases expression
EXP
Piperonyl Butoxide results in increased expression of RPS4X mRNA
CTD
PMID:15890375
NCBI chr X:67,298,522...67,302,965
Ensembl chr X:67,298,525...67,303,019 Ensembl chr 4:67,298,525...67,303,019
G
Rps7
ribosomal protein S7
increases expression
EXP
Piperonyl Butoxide results in increased expression of RPS7 mRNA
CTD
PMID:15890375
NCBI chr 6:45,266,200...45,271,064
Ensembl chr 6:45,223,980...45,271,145
G
Rpsa
ribosomal protein SA
increases expression
EXP
Piperonyl Butoxide results in increased expression of RPSA mRNA
CTD
PMID:15890375
NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247
G
Rrm2
ribonucleotide reductase regulatory subunit M2
increases expression
EXP
Piperonyl Butoxide results in increased expression of RRM2 mRNA
CTD
PMID:22484513
NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
G
Rtfdc1
replication termination factor 2 domain containing 1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of RTF2 gene
CTD
PMID:23968726
NCBI chr 3:161,208,005...161,237,687
Ensembl chr 3:161,208,049...161,237,687
G
S1pr1
sphingosine-1-phosphate receptor 1
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of S1PR1 mRNA
CTD
PMID:22484513
NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
G
Scamp4
secretory carrier membrane protein 4
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of SCAMP4 gene
CTD
PMID:23968726
NCBI chr 7:9,101,504...9,113,929
Ensembl chr 7:9,101,489...9,113,967
G
Scd
stearoyl-CoA desaturase
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of SCD1 mRNA
CTD
PMID:22484513
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
G
Scn4a
sodium voltage-gated channel alpha subunit 4
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of SCN4A gene
CTD
PMID:23968726
NCBI chr10:91,246,936...91,296,670
Ensembl chr10:91,246,936...91,296,545
G
Scpep1
serine carboxypeptidase 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of SCPEP1 mRNA
CTD
PMID:22484513
NCBI chr10:73,703,275...73,732,892
Ensembl chr10:73,703,278...73,732,850
G
Sds
serine dehydratase
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of SDS mRNA
CTD
PMID:22484513
NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
G
Selenow
selenoprotein W
increases expression
EXP
Piperonyl Butoxide results in increased expression of SELENOW mRNA
CTD
PMID:15890375
NCBI chr 1:76,599,441...76,604,514
Ensembl chr 1:76,598,779...76,604,724 Ensembl chr 1:76,598,779...76,604,724
G
Sema3b
semaphorin 3B
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of SEMA3B gene
CTD
PMID:23968726
NCBI chr 8:108,271,663...108,280,326
Ensembl chr 8:108,271,666...108,282,919
G
Serpina3n
serpin family A member 3N
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of SERPINA3N mRNA
CTD
PMID:22484513
NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433
G
Sesn1
sestrin 1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of SESN1 gene
CTD
PMID:23968726
NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697
G
Setd4
SET domain containing 4
increases expression
EXP
Piperonyl Butoxide results in increased expression of SETD4 mRNA
CTD
PMID:22484513
NCBI chr11:32,829,509...32,859,162
Ensembl chr11:32,838,063...32,858,243
G
Sh3d21
SH3 domain containing 21
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of SH3D21 gene
CTD
PMID:23968726
NCBI chr 5:138,429,180...138,444,540
Ensembl chr 5:138,429,180...138,444,407
G
Shh
sonic hedgehog signaling molecule
multiple interactions
ISO
Piperonyl Butoxide inhibits the reaction [SHH protein results in increased expression of GLI1 mRNA]
CTD
PMID:31642701
NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
G
Sik2
salt-inducible kinase 2
increases expression
EXP
Piperonyl Butoxide results in increased expression of SIK2 mRNA
CTD
PMID:22484513
NCBI chr 8:51,225,543...51,325,343
Ensembl chr 8:51,225,543...51,325,415
G
Slc13a2
solute carrier family 13 member 2
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of SLC13A2 gene
CTD
PMID:23968726
NCBI chr10:63,291,813...63,319,127
Ensembl chr10:63,291,815...63,319,127
G
Slc22a18
solute carrier family 22, member 18
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of SLC22A18 gene
CTD
PMID:23968726
NCBI chr 1:198,670,626...198,694,977
Ensembl chr 1:198,671,731...198,694,975
G
Slc22a8
solute carrier family 22 member 8
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of SLC22A8 mRNA
CTD
PMID:22484513
NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
G
Slc24a5
solute carrier family 24 member 5
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of SLC24A5 gene
CTD
PMID:23968726
NCBI chr 3:112,319,349...112,338,889
Ensembl chr 3:112,319,308...112,339,231
G
Slc26a9
solute carrier family 26 member 9
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of SLC26A9 gene
CTD
PMID:23968726
NCBI chr13:43,177,806...43,205,450
Ensembl chr13:43,177,867...43,204,330
G
Slc2a1
solute carrier family 2 member 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of SLC2A1 protein
CTD
PMID:28903497
NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
G
Slc37a4
solute carrier family 37 member 4
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of SLC37A4 mRNA
CTD
PMID:22484513
NCBI chr 8:44,723,216...44,729,301
Ensembl chr 8:44,723,339...44,729,301
G
Slc3a2
solute carrier family 3 member 2
increases expression
EXP
Piperonyl Butoxide results in increased expression of SLC3A2 mRNA
CTD
PMID:22484513
NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
G
Slc7a5
solute carrier family 7 member 5
increases expression
EXP
Piperonyl Butoxide results in increased expression of SLC7A5 mRNA
CTD
PMID:17498859
NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
G
Slco1a4
solute carrier organic anion transporter family, member 1a4
increases expression
EXP
Piperonyl Butoxide results in increased expression of SLCO1A4 mRNA
CTD
PMID:22484513
NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
G
Slk
STE20-like kinase
multiple interactions
EXP
[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in decreased expression of SLK protein
CTD
PMID:27914986
NCBI chr 1:246,473,712...246,529,643
Ensembl chr 1:246,473,712...246,526,530
G
Smo
smoothened, frizzled class receptor
multiple interactions
ISO
Piperonyl Butoxide inhibits the reaction [SMO protein results in increased expression of GLI1 protein]
CTD
PMID:31642701
NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829
G
Smoc1
SPARC related modular calcium binding 1
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of SMOC1 mRNA
CTD
PMID:22484513
NCBI chr 6:100,701,330...100,897,441
Ensembl chr 6:100,701,346...100,862,699
G
Spc24
SPC24 component of NDC80 kinetochore complex
increases expression
EXP
Piperonyl Butoxide results in increased expression of SPC24 mRNA
CTD
PMID:22484513
NCBI chr 8:20,300,315...20,305,354
Ensembl chr 8:20,300,319...20,305,310
G
Spc25
SPC25 component of NDC80 kinetochore complex
increases expression
EXP
Piperonyl Butoxide results in increased expression of SPC25 mRNA
CTD
PMID:22484513
NCBI chr 3:53,930,013...53,988,940
Ensembl chr 3:53,975,704...53,988,959
G
Spen
spen family transcriptional repressor
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of SPEN gene
CTD
PMID:23968726
NCBI chr 5:153,775,287...153,848,677
Ensembl chr 5:153,776,234...153,848,811
G
Srxn1
sulfiredoxin 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of SRXN1 mRNA
CTD
PMID:22484513
NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
G
Ssc5d
scavenger receptor cysteine rich family member with 5 domains
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of SSC5D gene
CTD
PMID:23968726
NCBI chr 1:68,891,942...68,910,462
Ensembl chr 1:68,891,949...68,909,743
G
Sstr4
somatostatin receptor 4
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of SSTR4 gene
CTD
PMID:23968726
NCBI chr 3:135,854,826...135,856,689
Ensembl chr 3:135,854,826...135,856,689
G
St6galnac6
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of ST6GALNAC6 gene
CTD
PMID:23968726
NCBI chr 3:15,894,275...15,907,502
Ensembl chr 3:15,885,968...15,907,496
G
Stbd1
starch binding domain 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of STBD1 mRNA
CTD
PMID:22484513
NCBI chr14:15,470,452...15,473,857
Ensembl chr14:15,469,582...15,477,443
G
Stip1
stress-induced phosphoprotein 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of STIP1 mRNA
CTD
PMID:22484513
NCBI chr 1:204,209,433...204,228,452
Ensembl chr 1:204,178,932...204,228,476
G
Stmn1
stathmin 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of STMN1 mRNA
CTD
PMID:15890375 PMID:22484513
NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
G
Tat
tyrosine aminotransferase
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of TAT mRNA
CTD
PMID:15890375
NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
G
Tenm2
teneurin transmembrane protein 2
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of TENM2 gene
CTD
PMID:23968726
NCBI chr10:20,480,662...21,706,415
Ensembl chr10:20,481,854...21,705,597
G
Th
tyrosine hydroxylase
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of TH gene
CTD
PMID:23968726
NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
G
Thada
THADA, armadillo repeat containing
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of THADA gene
CTD
PMID:23968726
NCBI chr 6:10,183,942...10,488,007
Ensembl chr 6:10,183,982...10,487,159
G
Thrsp
thyroid hormone responsive
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of THRSP mRNA
CTD
PMID:22484513
NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
G
Timm10b
translocase of inner mitochondrial membrane 10B
increases expression
EXP
Piperonyl Butoxide results in increased expression of TIMM10B mRNA
CTD
PMID:15890375
NCBI chr 1:159,980,525...159,983,371
Ensembl chr 1:159,980,484...159,981,642
G
Timp1
TIMP metallopeptidase inhibitor 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of TIMP1 mRNA
CTD
PMID:15890375
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
G
Tkfc
triokinase and FMN cyclase
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of TKFC mRNA
CTD
PMID:22484513
NCBI chr 1:207,238,230...207,253,035
Ensembl chr 1:207,236,557...207,252,737
G
Tmem70
transmembrane protein 70
multiple interactions
EXP
[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in decreased expression of TMEM70 protein
CTD
PMID:27914986 PMID:28903497
NCBI chr 5:2,637,102...2,654,729
Ensembl chr 5:2,637,102...2,654,729
G
Tmx1
thioredoxin-related transmembrane protein 1
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of TMX1 gene
CTD
PMID:23968726
NCBI chr 6:88,960,691...88,971,744
Ensembl chr 6:88,960,695...88,971,301
G
Tnfaip3
TNF alpha induced protein 3
increases expression
ISO
Piperonyl Butoxide results in increased expression of TNFAIP3 mRNA
CTD
PMID:21873647
NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
G
Tnni2
troponin I2, fast skeletal type
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of TNNI2 gene
CTD
PMID:23968726
NCBI chr 1:197,595,012...197,597,554
Ensembl chr 1:197,594,813...197,597,560
G
Top2a
DNA topoisomerase II alpha
increases expression
EXP
Piperonyl Butoxide results in increased expression of TOP2A mRNA
CTD
PMID:15890375
NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
G
Tpd52
tumor protein D52
decreases expression
ISO
Piperonyl Butoxide results in decreased expression of TPD52 mRNA
CTD
PMID:21873647
NCBI chr 2:92,735,365...92,816,079
Ensembl chr 2:92,735,620...92,816,622
G
Trappc10
trafficking protein particle complex subunit 10
increases expression
EXP
Piperonyl Butoxide results in increased expression of TRAPPC10 mRNA
CTD
PMID:22484513
NCBI chr20:10,438,737...10,499,074
Ensembl chr20:10,438,737...10,499,074
G
Trpm4
transient receptor potential cation channel, subfamily M, member 4
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of TRPM4 gene
CTD
PMID:23968726
NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532
G
Tsc22d1
TSC22 domain family, member 1
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of TSC22D1 mRNA
CTD
PMID:15890375
NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958
G
Tuba1c
tubulin, alpha 1C
increases expression
EXP
Piperonyl Butoxide results in increased expression of TUBA1C mRNA
CTD
PMID:15890375
NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647 Ensembl chr X:130,192,016...130,199,647
G
Tuba4a
tubulin, alpha 4A
increases expression
EXP
Piperonyl Butoxide results in increased expression of TUBA4A mRNA
CTD
PMID:22484513
NCBI chr 9:76,709,617...76,714,327
Ensembl chr 9:76,709,614...76,713,918
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Tubb4b
tubulin, beta 4B class IVb
increases expression
EXP
Piperonyl Butoxide results in increased expression of TUBB4B mRNA
CTD
PMID:22484513
NCBI chr 3:8,037,838...8,040,294
Ensembl chr 3:8,037,799...8,040,296
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Tubb5
tubulin, beta 5 class I
increases expression
EXP
Piperonyl Butoxide results in increased expression of TUBB5 mRNA
CTD
PMID:15890375 PMID:22484513
NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
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Tulp4
TUB like protein 4
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of TULP4 gene
CTD
PMID:23968726
NCBI chr 1:46,682,416...46,813,167
Ensembl chr 1:46,682,863...46,809,688
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Txnrd1
thioredoxin reductase 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of TXNRD1 mRNA
CTD
PMID:22484513
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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Tyms
thymidylate synthetase
increases expression
EXP
Piperonyl Butoxide results in increased expression of TYMS mRNA
CTD
PMID:15890375
NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
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Ube2e2
ubiquitin-conjugating enzyme E2E 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in decreased expression of UBE2E2 protein
CTD
PMID:27914986
NCBI chr15:6,980,241...7,257,912
Ensembl chr15:6,980,474...7,257,532
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Ugt2b1
UDP glucuronosyltransferase 2 family, polypeptide B1
multiple interactions increases expression
EXP
[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of UGT2B17 mRNA; Triterpenes promotes the reaction [Piperonyl Butoxide results in increased expression of UGT2B17 mRNA] Piperonyl Butoxide results in increased expression of UGT2B1 mRNA; Piperonyl Butoxide results in increased expression of UGT2B17 mRNA
CTD
PMID:17498859 PMID:18544911 PMID:18648771 PMID:22484513
NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
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Unc5a
unc-5 netrin receptor A
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of UNC5A gene
CTD
PMID:23968726
NCBI chr17:9,614,841...9,670,558
Ensembl chr17:9,614,838...9,670,526
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Usp5
ubiquitin specific peptidase 5
increases expression
EXP
Piperonyl Butoxide results in increased expression of USP5 mRNA
CTD
PMID:22484513
NCBI chr 4:157,619,663...157,634,681
Ensembl chr 4:157,619,643...157,634,711
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Vegfa
vascular endothelial growth factor A
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of VEGFA mRNA
CTD
PMID:15890375
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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Vnn1
vanin 1
increases expression
EXP
Piperonyl Butoxide results in increased expression of VNN1 mRNA
CTD
PMID:22484513
NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
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Vps50
VPS50 subunit of EARP/GARPII complex
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of VPS50 gene
CTD
PMID:23968726
NCBI chr 4:31,484,424...31,585,617
Ensembl chr 4:31,484,463...31,585,617
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Wdr6
WD repeat domain 6
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of WDR6 gene
CTD
PMID:23968726
NCBI chr 8:109,268,079...109,274,504
Ensembl chr 8:109,268,079...109,274,499
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Wdr90
WD repeat domain 90
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the expression of WDR90 protein; [Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of WDR90 gene
CTD
PMID:23968726
NCBI chr10:14,864,672...14,881,285
Ensembl chr10:14,864,670...14,881,292
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Wnt4
Wnt family member 4
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of WNT4 gene
CTD
PMID:23968726
NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859
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Xdh
xanthine dehydrogenase
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of XDH mRNA
CTD
PMID:15890375
NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
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Xrcc1
X-ray repair cross complementing 1
decreases expression
ISO
Piperonyl Butoxide results in decreased expression of XRCC1 mRNA
CTD
PMID:17014948
NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701
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Xrcc5
X-ray repair cross complementing 5
affects expression multiple interactions
ISO
Piperonyl Butoxide affects the expression of XRCC5 mRNA [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of XRCC5 mRNA
CTD
PMID:17014948 PMID:19690152
NCBI chr 9:73,955,216...74,044,020
Ensembl chr 9:73,955,216...74,044,018
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Zbtb2
zinc finger and BTB domain containing 2
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of ZBTB2 gene
CTD
PMID:23968726
NCBI chr 1:40,827,457...40,846,733
Ensembl chr 1:40,827,457...40,846,594
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Zbtb42
zinc finger and BTB domain containing 42
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of ZBTB42 gene
CTD
PMID:23968726
NCBI chr 6:131,734,257...131,742,459
Ensembl chr 6:131,738,356...131,742,685
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Zdhhc2
zinc finger DHHC-type palmitoyltransferase 2
increases expression
EXP
Piperonyl Butoxide results in increased expression of ZDHHC2 mRNA
CTD
PMID:22484513
NCBI chr16:51,808,465...51,878,060
Ensembl chr16:51,808,468...51,878,060
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Zfp385a
zinc finger protein 385A
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of ZFP385A gene
CTD
PMID:23968726
NCBI chr 7:134,448,914...134,475,548
Ensembl chr 7:134,448,921...134,475,548
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Zfp444
zinc finger protein 444
increases expression
EXP
Piperonyl Butoxide results in increased expression of ZFP444 mRNA
CTD
PMID:22484513
NCBI chr 1:67,709,052...67,729,283
Ensembl chr 1:67,711,152...67,728,367
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Zfp512
zinc finger protein 512
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of ZFP512 gene
CTD
PMID:23968726
NCBI chr 6:24,976,903...25,007,913
Ensembl chr 6:24,976,906...25,007,819
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Zfp526
zinc finger protein 526
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of ZFP526 gene
CTD
PMID:23968726
NCBI chr 1:80,807,791...80,817,852
Ensembl chr 1:80,806,972...80,818,180
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Zfp689
zinc finger protein 689
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of ZFP689 gene
CTD
PMID:23968726
NCBI chr 1:182,065,885...182,074,343
Ensembl chr 1:182,065,826...182,076,679
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Zfp787
zinc finger protein 787
multiple interactions
ISO
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of ZFP787 gene
CTD
PMID:23968726
NCBI chr 1:67,745,702...67,771,132
Ensembl chr 1:67,758,757...67,771,132
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Zic1
Zic family member 1
decreases expression
EXP
Piperonyl Butoxide results in decreased expression of ZIC1 mRNA
CTD
PMID:22484513
NCBI chr 8:91,908,548...91,918,020
Ensembl chr 8:91,908,576...91,912,731
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Zmat3
zinc finger, matrin type 3
increases expression
EXP
Piperonyl Butoxide results in increased expression of ZMAT3 mRNA
CTD
PMID:15890375
NCBI chr 2:115,106,046...115,136,888
Ensembl chr 2:115,106,966...115,136,863
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Zwint
ZW10 interacting kinetochore protein
increases expression
EXP
Piperonyl Butoxide results in increased expression of ZWINT mRNA
CTD
PMID:22484513
NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957
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